Harald L Janovjak

Janovjak Group

54 Publications

Mark all

[54]
2021 | Journal Article | IST-REx-ID: 10144 | OA
Rauschendorfer, Theresa, Selina Gurri, Irina Heggli, Luigi Maddaluno, Michael Meyer, Álvaro Inglés Prieto, Harald L Janovjak, and Sabine Werner. “Acute and Chronic Effects of a Light-Activated FGF Receptor in Keratinocytes in Vitro and in Mice.” Life Science Alliance. Life Science Alliance, 2021. https://doi.org/10.26508/lsa.202101100.
[Published Version] View | Files available | DOI | PubMed | Europe PMC
 
[53]
2021 | Journal Article | IST-REx-ID: 9363 | OA
Inglés Prieto, Álvaro, Nikolas Furthmann, Samuel H. Crossman, Alexandra Madelaine Tichy, Nina Hoyer, Meike Petersen, Vanessa Zheden, et al. “Optogenetic Delivery of Trophic Signals in a Genetic Model of Parkinson’s Disease.” PLoS Genetics. Public Library of Science, 2021. https://doi.org/10.1371/journal.pgen.1009479.
[Published Version] View | Files available | DOI | WoS
 
[52]
2020 | Book Chapter | IST-REx-ID: 8173
Kainrath, Stephanie, and Harald L Janovjak. “Design and Application of Light-Regulated Receptor Tyrosine Kinases.” In Photoswitching Proteins, edited by Dominik Niopek, 2173:233–46. MIMB. Springer Nature, 2020. https://doi.org/10.1007/978-1-0716-0755-8_16.
View | DOI
 
[51]
2020 | Journal Article | IST-REx-ID: 8674 | OA
Henneberger C, Bard L, Panatier A, Reynolds JP, Kopach O, Medvedev NI, Minge D, Herde MK, Anders S, Kraev I, Heller JP, Rama S, Zheng K, Jensen TP, Sanchez-Romero I, Jackson CJ, Janovjak HL, Ottersen OP, Nagelhus EA, Oliet SHR, Stewart MG, Nägerl UVa, Rusakov DA. 2020. LTP induction boosts glutamate spillover by driving withdrawal of perisynaptic astroglia. Neuron. 108(5), P919–936.E11.
[Published Version] View | Files available | DOI | WoS | PubMed | Europe PMC
 
[50]
2019 | Journal Article | IST-REx-ID: 6025 | OA
Capek, Daniel, Michael Smutny, Alexandra Madelaine Tichy, Maurizio Morri, Harald L Janovjak, and Carl-Philipp J Heisenberg. “Light-Activated Frizzled7 Reveals a Permissive Role of Non-Canonical Wnt Signaling in Mesendoderm Cell Migration.” ELife. eLife Sciences Publications, 2019. https://doi.org/10.7554/eLife.42093.
[Published Version] View | Files available | DOI | WoS
 
[49]
2019 | Journal Article | IST-REx-ID: 6564 | OA
Tichy, Alexandra-Madelaine, Elliot J. Gerrard, Julien M.D. Legrand, Robin M. Hobbs, and Harald L Janovjak. “Engineering Strategy and Vector Library for the Rapid Generation of Modular Light-Controlled Protein–Protein Interactions.” Journal of Molecular Biology. Elsevier, 2019. https://doi.org/10.1016/j.jmb.2019.05.033.
[Preprint] View | DOI | Download Preprint (ext.) | WoS
 
[48]
2019 | Journal Article | IST-REx-ID: 7406
Mckenzie, Catherine, Miroslava Spanova, Alexander J Johnson, Stephanie Kainrath, Vanessa Zheden, Harald H. Sitte, and Harald L Janovjak. “Isolation of Synaptic Vesicles from Genetically Engineered Cultured Neurons.” Journal of Neuroscience Methods. Elsevier, 2019. https://doi.org/10.1016/j.jneumeth.2018.11.018.
View | DOI | WoS | PubMed | Europe PMC
 
[47]
2018 | Journal Article | IST-REx-ID: 137 | OA
Zhang, William, Michel Herde, Joshua Mitchell, Jason Whitfield, Andreas Wulff, Vanessa Vongsouthi, Inmaculada Sanchez-Romero, et al. “Monitoring Hippocampal Glycine with the Computationally Designed Optical Sensor GlyFS.” Nature Chemical Biology. Nature Publishing Group, 2018. https://doi.org/10.1038/s41589-018-0108-2.
[Submitted Version] View | DOI | Download Submitted Version (ext.) | WoS | PubMed | Europe PMC
 
[46]
2018 | Journal Article | IST-REx-ID: 5984 | OA
Morri, Maurizio, Inmaculada Sanchez-Romero, Alexandra-Madelaine Tichy, Stephanie Kainrath, Elliot J. Gerrard, Priscila Hirschfeld, Jan Schwarz, and Harald L Janovjak. “Optical Functionalization of Human Class A Orphan G-Protein-Coupled Receptors.” Nature Communications. Springer Nature, 2018. https://doi.org/10.1038/s41467-018-04342-1.
[Published Version] View | Files available | DOI | WoS
 
[45]
2017 | Journal Article | IST-REx-ID: 538 | OA
Kainrath, Stephanie, Manuela Stadler, Eva Gschaider-Reichhart, Martin Distel, and Harald L Janovjak. “Grünlicht-Induzierte Rezeptorinaktivierung Durch Cobalamin-Bindende Domänen.” Angewandte Chemie. Wiley, 2017. https://doi.org/10.1002/ange.201611998.
[Published Version] View | Files available | DOI
 
[44]
2017 | Book Chapter | IST-REx-ID: 957
Clifton, Ben, Jason Whitfield, Inmaculada Sanchez-Romero, Michel Herde, Christian Henneberger, Harald L Janovjak, and Colin Jackson. “Ancestral Protein Reconstruction and Circular Permutation for Improving the Stability and Dynamic Range of FRET Sensors.” In Synthetic Protein Switches, edited by Viktor Stein, 1596:71–87. Synthetic Protein Switches. Springer, 2017. https://doi.org/10.1007/978-1-4939-6940-1_5.
View | DOI
 
[43]
2017 | Book Chapter | IST-REx-ID: 958
Mitchell, Joshua, William Zhang, Michel Herde, Christian Henneberger, Harald L Janovjak, Megan O’Mara, and Colin Jackson. “Method for Developing Optical Sensors Using a Synthetic Dye Fluorescent Protein FRET Pair and Computational Modeling and Assessment.” In Synthetic Protein Switches, edited by Viktor Stein, 1596:89–99. Synthetic Protein Switches. Springer, 2017. https://doi.org/10.1007/978-1-4939-6940-1_6.
View | DOI
 
[42]
2017 | Journal Article | IST-REx-ID: 1026
Agus, Viviana, and Harald L Janovjak. “Optogenetic Methods in Drug Screening: Technologies and Applications.” Current Opinion in Biotechnology. Elsevier, 2017. https://doi.org/10.1016/j.copbio.2017.02.006.
View | DOI | WoS
 
[41]
2017 | Journal Article | IST-REx-ID: 1028 | OA
Kainrath, Stephanie, Manuela Stadler, Eva Gschaider-Reichhart, Martin Distel, and Harald L Janovjak. “Green-Light-Induced Inactivation of Receptor Signaling Using Cobalamin-Binding Domains.” Angewandte Chemie - International Edition. Wiley-Blackwell, 2017. https://doi.org/10.1002/anie.201611998.
[Published Version] View | Files available | DOI | WoS
 
[40]
2016 | Journal Article | IST-REx-ID: 1440
Janovjak, Harald L. “Light at the End of the Protein: Crystal Structure of a C-Terminal Light-Sensing Domain.” Structure. Cell Press, 2016. https://doi.org/10.1016/j.str.2016.01.002.
View | DOI
 
[39]
2016 | Journal Article | IST-REx-ID: 1101
Mitchell, Joshua, Jason Whitfield, William Zhang, Christian Henneberger, Harald L Janovjak, Megan O’Mara, and Colin Jackson. “Rangefinder: A Semisynthetic FRET Sensor Design Algorithm.” ACS SENSORS. American Chemical Society, 2016. https://doi.org/10.1021/acssensors.6b00576.
View | DOI
 
[38]
2016 | Journal Article | IST-REx-ID: 1441 | OA
Gschaider-Reichhart, Eva, Álvaro Inglés Prieto, Alexandra-Madelaine Tichy, Catherine Mckenzie, and Harald L Janovjak. “A Phytochrome Sensory Domain Permits Receptor Activation by Red Light.” Angewandte Chemie - International Edition. Wiley, 2016. https://doi.org/10.1002/anie.201601736.
[Submitted Version] View | Files available | DOI
 
[37]
2016 | Journal Article | IST-REx-ID: 1100 | OA
Sako, Keisuke, Saurabh Pradhan, Vanessa Barone, Álvaro Inglés Prieto, Patrick Mueller, Verena Ruprecht, Daniel Capek, Sanjeev Galande, Harald L Janovjak, and Carl-Philipp J Heisenberg. “Optogenetic Control of Nodal Signaling Reveals a Temporal Pattern of Nodal Signaling Regulating Cell Fate Specification during Gastrulation.” Cell Reports. Cell Press, 2016. https://doi.org/10.1016/j.celrep.2016.06.036.
[Published Version] View | Files available | DOI
 
[36]
2015 | Book Chapter | IST-REx-ID: 1549 | OA
Mckenzie, Catherine, Inmaculada Sanchez-Romero, and Harald L Janovjak. “Flipping the Photoswitch: Ion Channels under Light Control.” In Novel Chemical Tools to Study Ion Channel Biology, 869:101–17. Advances in Experimental Medicine and Biology. Springer, 2015. https://doi.org/10.1007/978-1-4939-2845-3_6.
[Submitted Version] View | Files available | DOI
 
[35]
2015 | Journal Article | IST-REx-ID: 1611 | OA
Whitfield, Jason, William Zhang, Michel Herde, Ben Clifton, Johanna Radziejewski, Harald L Janovjak, Christian Henneberger, and Colin Jackson. “Construction of a Robust and Sensitive Arginine Biosensor through Ancestral Protein Reconstruction.” Protein Science. Wiley, 2015. https://doi.org/10.1002/pro.2721.
[Submitted Version] View | DOI | Download Submitted Version (ext.) | PubMed | Europe PMC
 
[34]
2015 | Journal Article | IST-REx-ID: 1867
Hühner, Jens, Álvaro Inglés Prieto, Christian Neusüß, Michael Lämmerhofer, and Harald L Janovjak. “Quantification of Riboflavin, Flavin Mononucleotide, and Flavin Adenine Dinucleotide in Mammalian Model Cells by CE with LED-Induced Fluorescence Detection.” Electrophoresis. Wiley, 2015. https://doi.org/10.1002/elps.201400451.
View | DOI
 
[33]
2015 | Journal Article | IST-REx-ID: 1678 | OA
Inglés Prieto, Álvaro, Eva Gschaider-Reichhart, Markus Muellner, Matthias Nowak, Sebastian Nijman, Michael Grusch, and Harald L Janovjak. “Light-Assisted Small-Molecule Screening against Protein Kinases.” Nature Chemical Biology. Nature Publishing Group, 2015. https://doi.org/10.1038/nchembio.1933.
[Submitted Version] View | Files available | DOI
 
[32]
2014 | Journal Article | IST-REx-ID: 2032 | OA
Inglés Prieto, Álvaro, Eva Gschaider-Reichhart, Karin Schelch, Harald L Janovjak, and Michael Grusch. “The Optogenetic Promise for Oncology: Episode I.” Molecular and Cellular Oncology. Taylor & Francis, 2014. https://doi.org/10.4161/23723548.2014.964045.
[Published Version] View | Files available | DOI
 
[31]
2014 | Journal Article | IST-REx-ID: 2084 | OA
Grusch, Michael, Karin Schelch, Robert Riedler, Eva Gschaider-Reichhart, Christopher Differ, Walter Berger, Álvaro Inglés Prieto, and Harald L Janovjak. “Spatio-Temporally Precise Activation of Engineered Receptor Tyrosine Kinases by Light.” EMBO Journal. Wiley-Blackwell, 2014. https://doi.org/10.15252/embj.201387695.
[Submitted Version] View | Files available | DOI | Download Submitted Version (ext.)
 
[30]
2013 | Journal Article | IST-REx-ID: 2857 | OA
Szobota, Stephanie, Catherine Mckenzie, and Harald L Janovjak. “Optical Control of Ligand-Gated Ion Channels.” Methods in Molecular Biology. Springer, 2013. https://doi.org/10.1007/978-1-62703-351-0_32.
[Submitted Version] View | Files available | DOI
 
[29]
2013 | Journal Article | IST-REx-ID: 2856 | OA
Levitz, Joshua, Carlos Pantoja, Benjamin Gaub, Harald L Janovjak, Andreas Reiner, Adam Hoagland, David Schoppik, et al. “Optical Control of Metabotropic Glutamate Receptors.” Nature Neuroscience. Nature Publishing Group, 2013. https://doi.org/10.1038/nn.3346.
[Submitted Version] View | DOI | Download Submitted Version (ext.) | PubMed | Europe PMC
 
[28]
2011 | Journal Article | IST-REx-ID: 3405 | OA
Janovjak, Harald L, Guillaume Sandoz, and Ehud Isacoff. “Modern Ionotropic Glutamate Receptor with a K+ Selectivity Signature Sequence.” Nature Communications. Nature Publishing Group, 2011. https://doi.org/10.1038/ncomms1231.
[Submitted Version] View | Files available | DOI
 
[27]
2011 | Book Chapter | IST-REx-ID: 3724
Janovjak, Harald L, and Ehud Isacoff. “Structure-Based Design of Light-Controlled Proteins.” In Photosensitive Molecules for the Control of Biological Function, 55:233–66. Springer, 2011. https://doi.org/10.1007/978-1-61779-031-7_13.
View | DOI
 
[26]
2010 | Journal Article | IST-REx-ID: 3407
Janovjak, Harald L, Stephanie Szobota, Claire Wyart, Dirk Trauner, and Ehud Isacoff. “A Light-Gated, Potassium-Selective Glutamate Receptor for the Optical Inhibition of Neuronal Firing.” Nature Neuroscience. Nature Publishing Group, 2010. https://doi.org/10.1038/nn.2589.
View | DOI
 
[25]
2010 | Book Review | IST-REx-ID: 3406
Stawski, Philipp, Harald L Janovjak, and Dirk Trauner. “Pharmacology of Ionotropic Glutamate Receptors: A Structural Perspective.” Bioorganic and Medicinal Chemistry. Elsevier, 2010. https://doi.org/10.1016/j.bmc.2010.09.012.
View | DOI
 
[24]
2009 | Journal Article | IST-REx-ID: 3408
Szymczak, Piotr, and Harald L Janovjak. “Periodic Forces Trigger a Complex Mechanical Response in Ubiquitin.” Journal of Molecular Biology. Elsevier, 2009. https://doi.org/10.1016/j.jmb.2009.04.071.
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[23]
2008 | Book Review | IST-REx-ID: 3410
Janovjak, Harald L, Tanuj Sapra, Alexej Kedrov, and Daniel Mueller. “From Valleys to Ridges: Exploring the Energy Landscape of Single Membrane Proteins.” ChemPhysChem. Wiley-Blackwell, 2008. https://doi.org/10.1002/cphc.200700662.
View | DOI
 
[22]
2008 | Journal Article | IST-REx-ID: 3409
Struckmeier, Jens, Reiner Wahl, Mirko Leuschner, Joao Nunes, Harald L Janovjak, Ulrich Geisler, Gerd Hofmann, Torsten Jähnke, and Daniel Mueller. “Fully Automated Single-Molecule Force Spectroscopy for Screening Applications.” Nanotechnology. IOP Publishing Ltd., 2008. https://doi.org/10.1088/0957-4484/19/38/384020.
View | DOI
 
[21]
2008 | Book Chapter | IST-REx-ID: 3726
Engel, Andreas, Harald L Janovjak, Dimtrios Fotiadis, Alexej Kedrov, David Cisneros, and Daniel Mueller. “Single-Molecule Microscopy and Force Spectroscopy of Membrane Proteins.” In Single Molecules and Nanotechnology, 12:279–311. Springer, 2008. https://doi.org/10.1007/978-3-540-73924-1_11.
View | DOI
 
[20]
2007 | Journal Article | IST-REx-ID: 3411 | OA
Preiner, Johannes, Harald L Janovjak, Christian Rankl, Helene Knaus, David Cisneros, Alexej Kedrov, Ferry Kienberger, Daniel Mueller, and Peter Hinterdorfer. “Free Energy of Membrane Protein Unfolding Derived from Single-Molecule Force Measurements.” Biophysical Journal. Biophysical Society, 2007. https://doi.org/10.1529/biophysj.106.096982.
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[19]
2007 | Book Review | IST-REx-ID: 3412
Kedrov, Alexej, Harald L Janovjak, Tanuj Sapra, and Daniel Mueller. “Deciphering Molecular Interactions of Native Membrane Proteins by Single-Molecule Force Spectroscopy.” Annual Review of Biophysics. Annual Reviews, 2007. https://doi.org/10.1146/annurev.biophys.36.040306.132640.
View | DOI
 
[18]
2007 | Journal Article | IST-REx-ID: 3727
Bippes, Christian, Harald L Janovjak, Alexej Kedrov, and Daniel Mueller. “Digital Force-Feedback for Protein Unfolding Experiments Using Atomic Force Microscopy.” Nanotechnology. IOP Publishing Ltd., 2007. https://doi.org/10.1088/0957-4484/18/4/044022.
View | DOI
 
[17]
2007 | Journal Article | IST-REx-ID: 3723
Janovjak, Harald L, Helene Knaus, and Daniel Mueller. “Transmembrane Helices Have Rough Energy Surfaces.” Journal of the American Chemical Society. ACS, 2007. https://doi.org/10.1021/ja065684a.
View | DOI
 
[16]
2006 | Book Chapter | IST-REx-ID: 3404
Janovjak, Harald L, Ravi Sawhney, Martin Stark, and Daniel Mueller. “Atomic Force Microscopy.” In Techniques in Microscopy for Biomedical Applications, 2:213–84. World Scientific Publishing, 2006.
View
 
[15]
2006 | Journal Article | IST-REx-ID: 3413
Kessler, Max, Kay Gottschalk, Harald L Janovjak, Daniel Mueller, and Hermann Gaub. “Bacteriorhodopsin Folds into the Membrane against an External Force.” Journal of Molecular Biology. Elsevier, 2006. https://doi.org/10.1016/j.jmb.2005.12.065.
View | DOI
 
[14]
2006 | Journal Article | IST-REx-ID: 3414
Kedrov, Alexej, Harald L Janovjak, Christine Ziegler, Werner Kühlbrandt, and Daniel Mueller. “Observing Folding Pathways and Kinetics of a Single Sodium-Proton Antiporter from Escherichia Coli.” Journal of Molecular Biology. Elsevier, 2006. https://doi.org/10.1016/j.jmb.2005.10.028.
View | DOI
 
[13]
2006 | Book Review | IST-REx-ID: 3415
Janovjak, Harald L, Alexej Kedrov, David Cisneros, Tanuj Sapra, Jens Struckmeier, and Daniel Mueller. “Imaging and Detecting Molecular Interactions of Single Membrane Proteins.” Neurobiology of Aging. Elsevier, 2006. https://doi.org/10.1016/j.neurobiolaging.2005.03.031.
View | DOI
 
[12]
2006 | Journal Article | IST-REx-ID: 3729
Bippes, Christian, Andrew Humphris, Martin Stark, Daniel Mueller, and Harald L Janovjak. “Direct Measurement of Single-Molecule Visco-Elasticity in Atomic Force Microscope Force-Extension Experiments.” European Biophysics Journal. Springer, 2006. https://doi.org/10.1007/s00249-005-0023-9.
View | DOI
 
[11]
2006 | Journal Article | IST-REx-ID: 3728
Cieplak, Marek, Sławomir Filipek, Harald L Janovjak, and Krystiana Krzysko. “Pulling Single Bacteriorhodopsin out of a Membrane: Comparison of Simulation and Experiment.” Biochimica et Biophysica Acta (BBA) - Biomembranes. Elsevier, 2006. https://doi.org/10.1016/j.bbamem.2006.03.028.
View | DOI
 
[10]
2006 | Book Chapter | IST-REx-ID: 3722
Janovjak, Harald L, and Daniel Mueller. “Rastersondenmikroskopie.” In Bioanalytik. Spektrum Akademischer Verlag, 2006.
View
 
[9]
2005 | Journal Article | IST-REx-ID: 3417
Kuhn, Michael, Harald L Janovjak, Maurice Hubain, and Daniel Mueller. “Automated Alignment and Pattern Recognition of Single-Molecule Force Spectroscopy Data.” Journal of Microscopy. Wiley-Blackwell, 2005. https://doi.org/10.1111/j.1365-2818.2005.01478.x.
View | DOI
 
[8]
2005 | Journal Article | IST-REx-ID: 3416 | OA
Janovjak, Harald L, Tanuj Sapra, and Daniel Mueller. “Complex Stability of Single Proteins Explored by Forced Unfolding Experiments.” Biophysical Journal. Biophysical Society, 2005. https://doi.org/10.1529/biophysj.105.059774.
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[7]
2005 | Journal Article | IST-REx-ID: 3418
Janovjak, Harald L, Jens Struckmeier, and Daniel Mueller. “Hydrodynamic Effects in Fast AFM Single Molecule Force Measurements.” European Biophysics Journal. Springer, 2005. https://doi.org/10.1007/s00249-004-0430-3.
View | DOI
 
[6]
2005 | Journal Article | IST-REx-ID: 3721 | OA
Janovjak, Harald L, Daniel Mueller, and Andrew Humphris. “Molecular Force Modulation Spectroscopy Revealing the Dynamic Response of Single Bacteriorhodopsins.” Biophysical Journal. Biophysical Society, 2005. https://doi.org/10.1529/biophysj.104.052746.
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[5]
2004 | Journal Article | IST-REx-ID: 3420
Kedrov, Alexej, Christine Ziegler, Harald L Janovjak, Werner Kühlbrandt, and Daniel Mueller. “Controlled Unfolding and Refolding of a Single Sodium/Proton Antiporter Using Atomic Force Microscopy.” Journal of Molecular Biology. Elsevier, 2004. https://doi.org/10.1016/j.jmb.2004.05.026.
View | DOI
 
[4]
2004 | Journal Article | IST-REx-ID: 3419
Janovjak, Harald L, Jens Struckmeier, Maurice Hubain, Max Kessler, Alexej Kedrov, and Daniel Mueller. “Probing the Energy Landscape of the Membrane Protein Bacteriorhodopsin.” Structure. Cell Press, 2004. https://doi.org/10.1016/j.str.2004.03.016.
View | DOI
 
[3]
2003 | Journal Article | IST-REx-ID: 3725 | OA
Janovjak, Harald L, Max Kessler, Dieter Oesterhelt, Hermann Gaub, and Daniel Mueller. “Unfolding Pathways of Native Bacteriorhodopsin Depend on Temperature.” EMBO Journal. Wiley-Blackwell, 2003. https://doi.org/10.1093/emboj/cdg509.
View | DOI | Download (ext.)
 
[2]
2002 | Journal Article | IST-REx-ID: 3421
Mueller, Daniel, Harald L Janovjak, Tiina Lehto, Lars Kuerschner, and Kurt Anderson. “Observing Structure, Function and Assembly of Single Proteins by AFM.” Progress in Biophysics and Molecular Biology. Elsevier, 2002. https://doi.org/10.1016/S0079-6107(02)00009-3.
View | DOI | PubMed | Europe PMC
 
[1]
2002 | Journal Article | IST-REx-ID: 3422
Müller, Patrick, Harald L Janovjak, Andre Miserez, and Zuzana Dobbie. “Processing of Gene Expression Data Generated by Quantitative Real-Time RT-PCR.” Biotechniques. Informa Healthcare, 2002.
View | PubMed | Europe PMC
 
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54 Publications

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[54]
2021 | Journal Article | IST-REx-ID: 10144 | OA
Rauschendorfer, Theresa, Selina Gurri, Irina Heggli, Luigi Maddaluno, Michael Meyer, Álvaro Inglés Prieto, Harald L Janovjak, and Sabine Werner. “Acute and Chronic Effects of a Light-Activated FGF Receptor in Keratinocytes in Vitro and in Mice.” Life Science Alliance. Life Science Alliance, 2021. https://doi.org/10.26508/lsa.202101100.
[Published Version] View | Files available | DOI | PubMed | Europe PMC
 
[53]
2021 | Journal Article | IST-REx-ID: 9363 | OA
Inglés Prieto, Álvaro, Nikolas Furthmann, Samuel H. Crossman, Alexandra Madelaine Tichy, Nina Hoyer, Meike Petersen, Vanessa Zheden, et al. “Optogenetic Delivery of Trophic Signals in a Genetic Model of Parkinson’s Disease.” PLoS Genetics. Public Library of Science, 2021. https://doi.org/10.1371/journal.pgen.1009479.
[Published Version] View | Files available | DOI | WoS
 
[52]
2020 | Book Chapter | IST-REx-ID: 8173
Kainrath, Stephanie, and Harald L Janovjak. “Design and Application of Light-Regulated Receptor Tyrosine Kinases.” In Photoswitching Proteins, edited by Dominik Niopek, 2173:233–46. MIMB. Springer Nature, 2020. https://doi.org/10.1007/978-1-0716-0755-8_16.
View | DOI
 
[51]
2020 | Journal Article | IST-REx-ID: 8674 | OA
Henneberger C, Bard L, Panatier A, Reynolds JP, Kopach O, Medvedev NI, Minge D, Herde MK, Anders S, Kraev I, Heller JP, Rama S, Zheng K, Jensen TP, Sanchez-Romero I, Jackson CJ, Janovjak HL, Ottersen OP, Nagelhus EA, Oliet SHR, Stewart MG, Nägerl UVa, Rusakov DA. 2020. LTP induction boosts glutamate spillover by driving withdrawal of perisynaptic astroglia. Neuron. 108(5), P919–936.E11.
[Published Version] View | Files available | DOI | WoS | PubMed | Europe PMC
 
[50]
2019 | Journal Article | IST-REx-ID: 6025 | OA
Capek, Daniel, Michael Smutny, Alexandra Madelaine Tichy, Maurizio Morri, Harald L Janovjak, and Carl-Philipp J Heisenberg. “Light-Activated Frizzled7 Reveals a Permissive Role of Non-Canonical Wnt Signaling in Mesendoderm Cell Migration.” ELife. eLife Sciences Publications, 2019. https://doi.org/10.7554/eLife.42093.
[Published Version] View | Files available | DOI | WoS
 
[49]
2019 | Journal Article | IST-REx-ID: 6564 | OA
Tichy, Alexandra-Madelaine, Elliot J. Gerrard, Julien M.D. Legrand, Robin M. Hobbs, and Harald L Janovjak. “Engineering Strategy and Vector Library for the Rapid Generation of Modular Light-Controlled Protein–Protein Interactions.” Journal of Molecular Biology. Elsevier, 2019. https://doi.org/10.1016/j.jmb.2019.05.033.
[Preprint] View | DOI | Download Preprint (ext.) | WoS
 
[48]
2019 | Journal Article | IST-REx-ID: 7406
Mckenzie, Catherine, Miroslava Spanova, Alexander J Johnson, Stephanie Kainrath, Vanessa Zheden, Harald H. Sitte, and Harald L Janovjak. “Isolation of Synaptic Vesicles from Genetically Engineered Cultured Neurons.” Journal of Neuroscience Methods. Elsevier, 2019. https://doi.org/10.1016/j.jneumeth.2018.11.018.
View | DOI | WoS | PubMed | Europe PMC
 
[47]
2018 | Journal Article | IST-REx-ID: 137 | OA
Zhang, William, Michel Herde, Joshua Mitchell, Jason Whitfield, Andreas Wulff, Vanessa Vongsouthi, Inmaculada Sanchez-Romero, et al. “Monitoring Hippocampal Glycine with the Computationally Designed Optical Sensor GlyFS.” Nature Chemical Biology. Nature Publishing Group, 2018. https://doi.org/10.1038/s41589-018-0108-2.
[Submitted Version] View | DOI | Download Submitted Version (ext.) | WoS | PubMed | Europe PMC
 
[46]
2018 | Journal Article | IST-REx-ID: 5984 | OA
Morri, Maurizio, Inmaculada Sanchez-Romero, Alexandra-Madelaine Tichy, Stephanie Kainrath, Elliot J. Gerrard, Priscila Hirschfeld, Jan Schwarz, and Harald L Janovjak. “Optical Functionalization of Human Class A Orphan G-Protein-Coupled Receptors.” Nature Communications. Springer Nature, 2018. https://doi.org/10.1038/s41467-018-04342-1.
[Published Version] View | Files available | DOI | WoS
 
[45]
2017 | Journal Article | IST-REx-ID: 538 | OA
Kainrath, Stephanie, Manuela Stadler, Eva Gschaider-Reichhart, Martin Distel, and Harald L Janovjak. “Grünlicht-Induzierte Rezeptorinaktivierung Durch Cobalamin-Bindende Domänen.” Angewandte Chemie. Wiley, 2017. https://doi.org/10.1002/ange.201611998.
[Published Version] View | Files available | DOI
 
[44]
2017 | Book Chapter | IST-REx-ID: 957
Clifton, Ben, Jason Whitfield, Inmaculada Sanchez-Romero, Michel Herde, Christian Henneberger, Harald L Janovjak, and Colin Jackson. “Ancestral Protein Reconstruction and Circular Permutation for Improving the Stability and Dynamic Range of FRET Sensors.” In Synthetic Protein Switches, edited by Viktor Stein, 1596:71–87. Synthetic Protein Switches. Springer, 2017. https://doi.org/10.1007/978-1-4939-6940-1_5.
View | DOI
 
[43]
2017 | Book Chapter | IST-REx-ID: 958
Mitchell, Joshua, William Zhang, Michel Herde, Christian Henneberger, Harald L Janovjak, Megan O’Mara, and Colin Jackson. “Method for Developing Optical Sensors Using a Synthetic Dye Fluorescent Protein FRET Pair and Computational Modeling and Assessment.” In Synthetic Protein Switches, edited by Viktor Stein, 1596:89–99. Synthetic Protein Switches. Springer, 2017. https://doi.org/10.1007/978-1-4939-6940-1_6.
View | DOI
 
[42]
2017 | Journal Article | IST-REx-ID: 1026
Agus, Viviana, and Harald L Janovjak. “Optogenetic Methods in Drug Screening: Technologies and Applications.” Current Opinion in Biotechnology. Elsevier, 2017. https://doi.org/10.1016/j.copbio.2017.02.006.
View | DOI | WoS
 
[41]
2017 | Journal Article | IST-REx-ID: 1028 | OA
Kainrath, Stephanie, Manuela Stadler, Eva Gschaider-Reichhart, Martin Distel, and Harald L Janovjak. “Green-Light-Induced Inactivation of Receptor Signaling Using Cobalamin-Binding Domains.” Angewandte Chemie - International Edition. Wiley-Blackwell, 2017. https://doi.org/10.1002/anie.201611998.
[Published Version] View | Files available | DOI | WoS
 
[40]
2016 | Journal Article | IST-REx-ID: 1440
Janovjak, Harald L. “Light at the End of the Protein: Crystal Structure of a C-Terminal Light-Sensing Domain.” Structure. Cell Press, 2016. https://doi.org/10.1016/j.str.2016.01.002.
View | DOI
 
[39]
2016 | Journal Article | IST-REx-ID: 1101
Mitchell, Joshua, Jason Whitfield, William Zhang, Christian Henneberger, Harald L Janovjak, Megan O’Mara, and Colin Jackson. “Rangefinder: A Semisynthetic FRET Sensor Design Algorithm.” ACS SENSORS. American Chemical Society, 2016. https://doi.org/10.1021/acssensors.6b00576.
View | DOI
 
[38]
2016 | Journal Article | IST-REx-ID: 1441 | OA
Gschaider-Reichhart, Eva, Álvaro Inglés Prieto, Alexandra-Madelaine Tichy, Catherine Mckenzie, and Harald L Janovjak. “A Phytochrome Sensory Domain Permits Receptor Activation by Red Light.” Angewandte Chemie - International Edition. Wiley, 2016. https://doi.org/10.1002/anie.201601736.
[Submitted Version] View | Files available | DOI
 
[37]
2016 | Journal Article | IST-REx-ID: 1100 | OA
Sako, Keisuke, Saurabh Pradhan, Vanessa Barone, Álvaro Inglés Prieto, Patrick Mueller, Verena Ruprecht, Daniel Capek, Sanjeev Galande, Harald L Janovjak, and Carl-Philipp J Heisenberg. “Optogenetic Control of Nodal Signaling Reveals a Temporal Pattern of Nodal Signaling Regulating Cell Fate Specification during Gastrulation.” Cell Reports. Cell Press, 2016. https://doi.org/10.1016/j.celrep.2016.06.036.
[Published Version] View | Files available | DOI
 
[36]
2015 | Book Chapter | IST-REx-ID: 1549 | OA
Mckenzie, Catherine, Inmaculada Sanchez-Romero, and Harald L Janovjak. “Flipping the Photoswitch: Ion Channels under Light Control.” In Novel Chemical Tools to Study Ion Channel Biology, 869:101–17. Advances in Experimental Medicine and Biology. Springer, 2015. https://doi.org/10.1007/978-1-4939-2845-3_6.
[Submitted Version] View | Files available | DOI
 
[35]
2015 | Journal Article | IST-REx-ID: 1611 | OA
Whitfield, Jason, William Zhang, Michel Herde, Ben Clifton, Johanna Radziejewski, Harald L Janovjak, Christian Henneberger, and Colin Jackson. “Construction of a Robust and Sensitive Arginine Biosensor through Ancestral Protein Reconstruction.” Protein Science. Wiley, 2015. https://doi.org/10.1002/pro.2721.
[Submitted Version] View | DOI | Download Submitted Version (ext.) | PubMed | Europe PMC
 
[34]
2015 | Journal Article | IST-REx-ID: 1867
Hühner, Jens, Álvaro Inglés Prieto, Christian Neusüß, Michael Lämmerhofer, and Harald L Janovjak. “Quantification of Riboflavin, Flavin Mononucleotide, and Flavin Adenine Dinucleotide in Mammalian Model Cells by CE with LED-Induced Fluorescence Detection.” Electrophoresis. Wiley, 2015. https://doi.org/10.1002/elps.201400451.
View | DOI
 
[33]
2015 | Journal Article | IST-REx-ID: 1678 | OA
Inglés Prieto, Álvaro, Eva Gschaider-Reichhart, Markus Muellner, Matthias Nowak, Sebastian Nijman, Michael Grusch, and Harald L Janovjak. “Light-Assisted Small-Molecule Screening against Protein Kinases.” Nature Chemical Biology. Nature Publishing Group, 2015. https://doi.org/10.1038/nchembio.1933.
[Submitted Version] View | Files available | DOI
 
[32]
2014 | Journal Article | IST-REx-ID: 2032 | OA
Inglés Prieto, Álvaro, Eva Gschaider-Reichhart, Karin Schelch, Harald L Janovjak, and Michael Grusch. “The Optogenetic Promise for Oncology: Episode I.” Molecular and Cellular Oncology. Taylor & Francis, 2014. https://doi.org/10.4161/23723548.2014.964045.
[Published Version] View | Files available | DOI
 
[31]
2014 | Journal Article | IST-REx-ID: 2084 | OA
Grusch, Michael, Karin Schelch, Robert Riedler, Eva Gschaider-Reichhart, Christopher Differ, Walter Berger, Álvaro Inglés Prieto, and Harald L Janovjak. “Spatio-Temporally Precise Activation of Engineered Receptor Tyrosine Kinases by Light.” EMBO Journal. Wiley-Blackwell, 2014. https://doi.org/10.15252/embj.201387695.
[Submitted Version] View | Files available | DOI | Download Submitted Version (ext.)
 
[30]
2013 | Journal Article | IST-REx-ID: 2857 | OA
Szobota, Stephanie, Catherine Mckenzie, and Harald L Janovjak. “Optical Control of Ligand-Gated Ion Channels.” Methods in Molecular Biology. Springer, 2013. https://doi.org/10.1007/978-1-62703-351-0_32.
[Submitted Version] View | Files available | DOI
 
[29]
2013 | Journal Article | IST-REx-ID: 2856 | OA
Levitz, Joshua, Carlos Pantoja, Benjamin Gaub, Harald L Janovjak, Andreas Reiner, Adam Hoagland, David Schoppik, et al. “Optical Control of Metabotropic Glutamate Receptors.” Nature Neuroscience. Nature Publishing Group, 2013. https://doi.org/10.1038/nn.3346.
[Submitted Version] View | DOI | Download Submitted Version (ext.) | PubMed | Europe PMC
 
[28]
2011 | Journal Article | IST-REx-ID: 3405 | OA
Janovjak, Harald L, Guillaume Sandoz, and Ehud Isacoff. “Modern Ionotropic Glutamate Receptor with a K+ Selectivity Signature Sequence.” Nature Communications. Nature Publishing Group, 2011. https://doi.org/10.1038/ncomms1231.
[Submitted Version] View | Files available | DOI
 
[27]
2011 | Book Chapter | IST-REx-ID: 3724
Janovjak, Harald L, and Ehud Isacoff. “Structure-Based Design of Light-Controlled Proteins.” In Photosensitive Molecules for the Control of Biological Function, 55:233–66. Springer, 2011. https://doi.org/10.1007/978-1-61779-031-7_13.
View | DOI
 
[26]
2010 | Journal Article | IST-REx-ID: 3407
Janovjak, Harald L, Stephanie Szobota, Claire Wyart, Dirk Trauner, and Ehud Isacoff. “A Light-Gated, Potassium-Selective Glutamate Receptor for the Optical Inhibition of Neuronal Firing.” Nature Neuroscience. Nature Publishing Group, 2010. https://doi.org/10.1038/nn.2589.
View | DOI
 
[25]
2010 | Book Review | IST-REx-ID: 3406
Stawski, Philipp, Harald L Janovjak, and Dirk Trauner. “Pharmacology of Ionotropic Glutamate Receptors: A Structural Perspective.” Bioorganic and Medicinal Chemistry. Elsevier, 2010. https://doi.org/10.1016/j.bmc.2010.09.012.
View | DOI
 
[24]
2009 | Journal Article | IST-REx-ID: 3408
Szymczak, Piotr, and Harald L Janovjak. “Periodic Forces Trigger a Complex Mechanical Response in Ubiquitin.” Journal of Molecular Biology. Elsevier, 2009. https://doi.org/10.1016/j.jmb.2009.04.071.
View | DOI
 
[23]
2008 | Book Review | IST-REx-ID: 3410
Janovjak, Harald L, Tanuj Sapra, Alexej Kedrov, and Daniel Mueller. “From Valleys to Ridges: Exploring the Energy Landscape of Single Membrane Proteins.” ChemPhysChem. Wiley-Blackwell, 2008. https://doi.org/10.1002/cphc.200700662.
View | DOI
 
[22]
2008 | Journal Article | IST-REx-ID: 3409
Struckmeier, Jens, Reiner Wahl, Mirko Leuschner, Joao Nunes, Harald L Janovjak, Ulrich Geisler, Gerd Hofmann, Torsten Jähnke, and Daniel Mueller. “Fully Automated Single-Molecule Force Spectroscopy for Screening Applications.” Nanotechnology. IOP Publishing Ltd., 2008. https://doi.org/10.1088/0957-4484/19/38/384020.
View | DOI
 
[21]
2008 | Book Chapter | IST-REx-ID: 3726
Engel, Andreas, Harald L Janovjak, Dimtrios Fotiadis, Alexej Kedrov, David Cisneros, and Daniel Mueller. “Single-Molecule Microscopy and Force Spectroscopy of Membrane Proteins.” In Single Molecules and Nanotechnology, 12:279–311. Springer, 2008. https://doi.org/10.1007/978-3-540-73924-1_11.
View | DOI
 
[20]
2007 | Journal Article | IST-REx-ID: 3411 | OA
Preiner, Johannes, Harald L Janovjak, Christian Rankl, Helene Knaus, David Cisneros, Alexej Kedrov, Ferry Kienberger, Daniel Mueller, and Peter Hinterdorfer. “Free Energy of Membrane Protein Unfolding Derived from Single-Molecule Force Measurements.” Biophysical Journal. Biophysical Society, 2007. https://doi.org/10.1529/biophysj.106.096982.
View | DOI | Download (ext.)
 
[19]
2007 | Book Review | IST-REx-ID: 3412
Kedrov, Alexej, Harald L Janovjak, Tanuj Sapra, and Daniel Mueller. “Deciphering Molecular Interactions of Native Membrane Proteins by Single-Molecule Force Spectroscopy.” Annual Review of Biophysics. Annual Reviews, 2007. https://doi.org/10.1146/annurev.biophys.36.040306.132640.
View | DOI
 
[18]
2007 | Journal Article | IST-REx-ID: 3727
Bippes, Christian, Harald L Janovjak, Alexej Kedrov, and Daniel Mueller. “Digital Force-Feedback for Protein Unfolding Experiments Using Atomic Force Microscopy.” Nanotechnology. IOP Publishing Ltd., 2007. https://doi.org/10.1088/0957-4484/18/4/044022.
View | DOI
 
[17]
2007 | Journal Article | IST-REx-ID: 3723
Janovjak, Harald L, Helene Knaus, and Daniel Mueller. “Transmembrane Helices Have Rough Energy Surfaces.” Journal of the American Chemical Society. ACS, 2007. https://doi.org/10.1021/ja065684a.
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[16]
2006 | Book Chapter | IST-REx-ID: 3404
Janovjak, Harald L, Ravi Sawhney, Martin Stark, and Daniel Mueller. “Atomic Force Microscopy.” In Techniques in Microscopy for Biomedical Applications, 2:213–84. World Scientific Publishing, 2006.
View
 
[15]
2006 | Journal Article | IST-REx-ID: 3413
Kessler, Max, Kay Gottschalk, Harald L Janovjak, Daniel Mueller, and Hermann Gaub. “Bacteriorhodopsin Folds into the Membrane against an External Force.” Journal of Molecular Biology. Elsevier, 2006. https://doi.org/10.1016/j.jmb.2005.12.065.
View | DOI
 
[14]
2006 | Journal Article | IST-REx-ID: 3414
Kedrov, Alexej, Harald L Janovjak, Christine Ziegler, Werner Kühlbrandt, and Daniel Mueller. “Observing Folding Pathways and Kinetics of a Single Sodium-Proton Antiporter from Escherichia Coli.” Journal of Molecular Biology. Elsevier, 2006. https://doi.org/10.1016/j.jmb.2005.10.028.
View | DOI
 
[13]
2006 | Book Review | IST-REx-ID: 3415
Janovjak, Harald L, Alexej Kedrov, David Cisneros, Tanuj Sapra, Jens Struckmeier, and Daniel Mueller. “Imaging and Detecting Molecular Interactions of Single Membrane Proteins.” Neurobiology of Aging. Elsevier, 2006. https://doi.org/10.1016/j.neurobiolaging.2005.03.031.
View | DOI
 
[12]
2006 | Journal Article | IST-REx-ID: 3729
Bippes, Christian, Andrew Humphris, Martin Stark, Daniel Mueller, and Harald L Janovjak. “Direct Measurement of Single-Molecule Visco-Elasticity in Atomic Force Microscope Force-Extension Experiments.” European Biophysics Journal. Springer, 2006. https://doi.org/10.1007/s00249-005-0023-9.
View | DOI
 
[11]
2006 | Journal Article | IST-REx-ID: 3728
Cieplak, Marek, Sławomir Filipek, Harald L Janovjak, and Krystiana Krzysko. “Pulling Single Bacteriorhodopsin out of a Membrane: Comparison of Simulation and Experiment.” Biochimica et Biophysica Acta (BBA) - Biomembranes. Elsevier, 2006. https://doi.org/10.1016/j.bbamem.2006.03.028.
View | DOI
 
[10]
2006 | Book Chapter | IST-REx-ID: 3722
Janovjak, Harald L, and Daniel Mueller. “Rastersondenmikroskopie.” In Bioanalytik. Spektrum Akademischer Verlag, 2006.
View
 
[9]
2005 | Journal Article | IST-REx-ID: 3417
Kuhn, Michael, Harald L Janovjak, Maurice Hubain, and Daniel Mueller. “Automated Alignment and Pattern Recognition of Single-Molecule Force Spectroscopy Data.” Journal of Microscopy. Wiley-Blackwell, 2005. https://doi.org/10.1111/j.1365-2818.2005.01478.x.
View | DOI
 
[8]
2005 | Journal Article | IST-REx-ID: 3416 | OA
Janovjak, Harald L, Tanuj Sapra, and Daniel Mueller. “Complex Stability of Single Proteins Explored by Forced Unfolding Experiments.” Biophysical Journal. Biophysical Society, 2005. https://doi.org/10.1529/biophysj.105.059774.
View | DOI | Download (ext.)
 
[7]
2005 | Journal Article | IST-REx-ID: 3418
Janovjak, Harald L, Jens Struckmeier, and Daniel Mueller. “Hydrodynamic Effects in Fast AFM Single Molecule Force Measurements.” European Biophysics Journal. Springer, 2005. https://doi.org/10.1007/s00249-004-0430-3.
View | DOI
 
[6]
2005 | Journal Article | IST-REx-ID: 3721 | OA
Janovjak, Harald L, Daniel Mueller, and Andrew Humphris. “Molecular Force Modulation Spectroscopy Revealing the Dynamic Response of Single Bacteriorhodopsins.” Biophysical Journal. Biophysical Society, 2005. https://doi.org/10.1529/biophysj.104.052746.
View | DOI | Download (ext.)
 
[5]
2004 | Journal Article | IST-REx-ID: 3420
Kedrov, Alexej, Christine Ziegler, Harald L Janovjak, Werner Kühlbrandt, and Daniel Mueller. “Controlled Unfolding and Refolding of a Single Sodium/Proton Antiporter Using Atomic Force Microscopy.” Journal of Molecular Biology. Elsevier, 2004. https://doi.org/10.1016/j.jmb.2004.05.026.
View | DOI
 
[4]
2004 | Journal Article | IST-REx-ID: 3419
Janovjak, Harald L, Jens Struckmeier, Maurice Hubain, Max Kessler, Alexej Kedrov, and Daniel Mueller. “Probing the Energy Landscape of the Membrane Protein Bacteriorhodopsin.” Structure. Cell Press, 2004. https://doi.org/10.1016/j.str.2004.03.016.
View | DOI
 
[3]
2003 | Journal Article | IST-REx-ID: 3725 | OA
Janovjak, Harald L, Max Kessler, Dieter Oesterhelt, Hermann Gaub, and Daniel Mueller. “Unfolding Pathways of Native Bacteriorhodopsin Depend on Temperature.” EMBO Journal. Wiley-Blackwell, 2003. https://doi.org/10.1093/emboj/cdg509.
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[2]
2002 | Journal Article | IST-REx-ID: 3421
Mueller, Daniel, Harald L Janovjak, Tiina Lehto, Lars Kuerschner, and Kurt Anderson. “Observing Structure, Function and Assembly of Single Proteins by AFM.” Progress in Biophysics and Molecular Biology. Elsevier, 2002. https://doi.org/10.1016/S0079-6107(02)00009-3.
View | DOI | PubMed | Europe PMC
 
[1]
2002 | Journal Article | IST-REx-ID: 3422
Müller, Patrick, Harald L Janovjak, Andre Miserez, and Zuzana Dobbie. “Processing of Gene Expression Data Generated by Quantitative Real-Time RT-PCR.” Biotechniques. Informa Healthcare, 2002.
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