---
_id: '7400'
abstract:
- lang: eng
text: 'Suppressed recombination allows divergence between homologous sex chromosomes
and the functionality of their genes. Here, we reveal patterns of the earliest
stages of sex-chromosome evolution in the diploid dioecious herb Mercurialis annua
on the basis of cytological analysis, de novo genome assembly and annotation,
genetic mapping, exome resequencing of natural populations, and transcriptome
analysis. The genome assembly contained 34,105 expressed genes, of which 10,076
were assigned to linkage groups. Genetic mapping and exome resequencing of individuals
across the species range both identified the largest linkage group, LG1, as the
sex chromosome. Although the sex chromosomes of M. annua are karyotypically homomorphic,
we estimate that about one-third of the Y chromosome, containing 568 transcripts
and spanning 22.3 cM in the corresponding female map, has ceased recombining.
Nevertheless, we found limited evidence for Y-chromosome degeneration in terms
of gene loss and pseudogenization, and most X- and Y-linked genes appear to have
diverged in the period subsequent to speciation between M. annua and its sister
species M. huetii, which shares the same sex-determining region. Taken together,
our results suggest that the M. annua Y chromosome has at least two evolutionary
strata: a small old stratum shared with M. huetii, and a more recent larger stratum
that is probably unique to M. annua and that stopped recombining ∼1 MYA. Patterns
of gene expression within the nonrecombining region are consistent with the idea
that sexually antagonistic selection may have played a role in favoring suppressed
recombination.'
article_processing_charge: No
article_type: original
author:
- first_name: Paris
full_name: Veltsos, Paris
last_name: Veltsos
- first_name: Kate E.
full_name: Ridout, Kate E.
last_name: Ridout
- first_name: Melissa A
full_name: Toups, Melissa A
id: 4E099E4E-F248-11E8-B48F-1D18A9856A87
last_name: Toups
orcid: 0000-0002-9752-7380
- first_name: Santiago C.
full_name: González-Martínez, Santiago C.
last_name: González-Martínez
- first_name: Aline
full_name: Muyle, Aline
last_name: Muyle
- first_name: Olivier
full_name: Emery, Olivier
last_name: Emery
- first_name: Pasi
full_name: Rastas, Pasi
last_name: Rastas
- first_name: Vojtech
full_name: Hudzieczek, Vojtech
last_name: Hudzieczek
- first_name: Roman
full_name: Hobza, Roman
last_name: Hobza
- first_name: Boris
full_name: Vyskot, Boris
last_name: Vyskot
- first_name: Gabriel A. B.
full_name: Marais, Gabriel A. B.
last_name: Marais
- first_name: Dmitry A.
full_name: Filatov, Dmitry A.
last_name: Filatov
- first_name: John R.
full_name: Pannell, John R.
last_name: Pannell
citation:
ama: Veltsos P, Ridout KE, Toups MA, et al. Early sex-chromosome evolution in the
diploid dioecious plant Mercurialis annua. Genetics. 2019;212(3):815-835.
doi:10.1534/genetics.119.302045
apa: Veltsos, P., Ridout, K. E., Toups, M. A., González-Martínez, S. C., Muyle,
A., Emery, O., … Pannell, J. R. (2019). Early sex-chromosome evolution in the
diploid dioecious plant Mercurialis annua. Genetics. Genetics Society of
America. https://doi.org/10.1534/genetics.119.302045
chicago: Veltsos, Paris, Kate E. Ridout, Melissa A Toups, Santiago C. González-Martínez,
Aline Muyle, Olivier Emery, Pasi Rastas, et al. “Early Sex-Chromosome Evolution
in the Diploid Dioecious Plant Mercurialis Annua.” Genetics. Genetics Society
of America, 2019. https://doi.org/10.1534/genetics.119.302045.
ieee: P. Veltsos et al., “Early sex-chromosome evolution in the diploid dioecious
plant Mercurialis annua,” Genetics, vol. 212, no. 3. Genetics Society of
America, pp. 815–835, 2019.
ista: Veltsos P, Ridout KE, Toups MA, González-Martínez SC, Muyle A, Emery O, Rastas
P, Hudzieczek V, Hobza R, Vyskot B, Marais GAB, Filatov DA, Pannell JR. 2019.
Early sex-chromosome evolution in the diploid dioecious plant Mercurialis annua.
Genetics. 212(3), 815–835.
mla: Veltsos, Paris, et al. “Early Sex-Chromosome Evolution in the Diploid Dioecious
Plant Mercurialis Annua.” Genetics, vol. 212, no. 3, Genetics Society of
America, 2019, pp. 815–35, doi:10.1534/genetics.119.302045.
short: P. Veltsos, K.E. Ridout, M.A. Toups, S.C. González-Martínez, A. Muyle, O.
Emery, P. Rastas, V. Hudzieczek, R. Hobza, B. Vyskot, G.A.B. Marais, D.A. Filatov,
J.R. Pannell, Genetics 212 (2019) 815–835.
date_created: 2020-01-29T16:15:44Z
date_published: 2019-07-01T00:00:00Z
date_updated: 2023-09-07T14:49:29Z
day: '01'
department:
- _id: BeVi
doi: 10.1534/genetics.119.302045
ec_funded: 1
external_id:
isi:
- '000474809300015'
pmid:
- '31113811'
intvolume: ' 212'
isi: 1
issue: '3'
language:
- iso: eng
main_file_link:
- open_access: '1'
url: https://doi.org/10.1534/genetics.119.302045
month: '07'
oa: 1
oa_version: Published Version
page: 815-835
pmid: 1
project:
- _id: 250BDE62-B435-11E9-9278-68D0E5697425
call_identifier: H2020
grant_number: '715257'
name: Prevalence and Influence of Sexual Antagonism on Genome Evolution
publication: Genetics
publication_identifier:
eissn:
- 1943-2631
issn:
- 0016-6731
publication_status: published
publisher: Genetics Society of America
quality_controlled: '1'
scopus_import: '1'
status: public
title: Early sex-chromosome evolution in the diploid dioecious plant Mercurialis annua
type: journal_article
user_id: c635000d-4b10-11ee-a964-aac5a93f6ac1
volume: 212
year: '2019'
...
---
_id: '7404'
abstract:
- lang: eng
text: The formation of neuronal dendrite branches is fundamental for the wiring
and function of the nervous system. Indeed, dendrite branching enhances the coverage
of the neuron's receptive field and modulates the initial processing of incoming
stimuli. Complex dendrite patterns are achieved in vivo through a dynamic process
of de novo branch formation, branch extension and retraction. The first step towards
branch formation is the generation of a dynamic filopodium-like branchlet. The
mechanisms underlying the initiation of dendrite branchlets are therefore crucial
to the shaping of dendrites. Through in vivo time-lapse imaging of the subcellular
localization of actin during the process of branching of Drosophila larva sensory
neurons, combined with genetic analysis and electron tomography, we have identified
the Actin-related protein (Arp) 2/3 complex as the major actin nucleator involved
in the initiation of dendrite branchlet formation, under the control of the activator
WAVE and of the small GTPase Rac1. Transient recruitment of an Arp2/3 component
marks the site of branchlet initiation in vivo. These data position the activation
of Arp2/3 as an early hub for the initiation of branchlet formation.
article_number: dev171397
article_processing_charge: No
article_type: original
author:
- first_name: Tomke
full_name: Stürner, Tomke
last_name: Stürner
- first_name: Anastasia
full_name: Tatarnikova, Anastasia
last_name: Tatarnikova
- first_name: Jan
full_name: Müller, Jan
id: AD07FDB4-0F61-11EA-8158-C4CC64CEAA8D
last_name: Müller
- first_name: Barbara
full_name: Schaffran, Barbara
last_name: Schaffran
- first_name: Hermann
full_name: Cuntz, Hermann
last_name: Cuntz
- first_name: Yun
full_name: Zhang, Yun
last_name: Zhang
- first_name: Maria
full_name: Nemethova, Maria
id: 34E27F1C-F248-11E8-B48F-1D18A9856A87
last_name: Nemethova
- first_name: Sven
full_name: Bogdan, Sven
last_name: Bogdan
- first_name: Vic
full_name: Small, Vic
last_name: Small
- first_name: Gaia
full_name: Tavosanis, Gaia
last_name: Tavosanis
citation:
ama: Stürner T, Tatarnikova A, Müller J, et al. Transient localization of the Arp2/3
complex initiates neuronal dendrite branching in vivo. Development. 2019;146(7).
doi:10.1242/dev.171397
apa: Stürner, T., Tatarnikova, A., Müller, J., Schaffran, B., Cuntz, H., Zhang,
Y., … Tavosanis, G. (2019). Transient localization of the Arp2/3 complex initiates
neuronal dendrite branching in vivo. Development. The Company of Biologists.
https://doi.org/10.1242/dev.171397
chicago: Stürner, Tomke, Anastasia Tatarnikova, Jan Müller, Barbara Schaffran, Hermann
Cuntz, Yun Zhang, Maria Nemethova, Sven Bogdan, Vic Small, and Gaia Tavosanis.
“Transient Localization of the Arp2/3 Complex Initiates Neuronal Dendrite Branching
in Vivo.” Development. The Company of Biologists, 2019. https://doi.org/10.1242/dev.171397.
ieee: T. Stürner et al., “Transient localization of the Arp2/3 complex initiates
neuronal dendrite branching in vivo,” Development, vol. 146, no. 7. The
Company of Biologists, 2019.
ista: Stürner T, Tatarnikova A, Müller J, Schaffran B, Cuntz H, Zhang Y, Nemethova
M, Bogdan S, Small V, Tavosanis G. 2019. Transient localization of the Arp2/3
complex initiates neuronal dendrite branching in vivo. Development. 146(7), dev171397.
mla: Stürner, Tomke, et al. “Transient Localization of the Arp2/3 Complex Initiates
Neuronal Dendrite Branching in Vivo.” Development, vol. 146, no. 7, dev171397,
The Company of Biologists, 2019, doi:10.1242/dev.171397.
short: T. Stürner, A. Tatarnikova, J. Müller, B. Schaffran, H. Cuntz, Y. Zhang,
M. Nemethova, S. Bogdan, V. Small, G. Tavosanis, Development 146 (2019).
date_created: 2020-01-29T16:27:10Z
date_published: 2019-04-04T00:00:00Z
date_updated: 2023-09-07T14:47:00Z
day: '04'
department:
- _id: MiSi
doi: 10.1242/dev.171397
external_id:
isi:
- '000464583200006'
pmid:
- '30910826'
intvolume: ' 146'
isi: 1
issue: '7'
language:
- iso: eng
main_file_link:
- open_access: '1'
url: https://doi.org/10.1242/dev.171397
month: '04'
oa: 1
oa_version: Published Version
pmid: 1
publication: Development
publication_identifier:
eissn:
- 1477-9129
issn:
- 0950-1991
publication_status: published
publisher: The Company of Biologists
quality_controlled: '1'
scopus_import: '1'
status: public
title: Transient localization of the Arp2/3 complex initiates neuronal dendrite branching
in vivo
type: journal_article
user_id: c635000d-4b10-11ee-a964-aac5a93f6ac1
volume: 146
year: '2019'
...
---
_id: '7402'
abstract:
- lang: eng
text: Graph planning gives rise to fundamental algorithmic questions such as shortest
path, traveling salesman problem, etc. A classical problem in discrete planning
is to consider a weighted graph and construct a path that maximizes the sum of
weights for a given time horizon T. However, in many scenarios, the time horizon
is not fixed, but the stopping time is chosen according to some distribution such
that the expected stopping time is T. If the stopping time distribution is not
known, then to ensure robustness, the distribution is chosen by an adversary,
to represent the worst-case scenario. A stationary plan for every vertex always
chooses the same outgoing edge. For fixed horizon or fixed stopping-time distribution,
stationary plans are not sufficient for optimality. Quite surprisingly we show
that when an adversary chooses the stopping-time distribution with expected stopping
time T, then stationary plans are sufficient. While computing optimal stationary
plans for fixed horizon is NP-complete, we show that computing optimal stationary
plans under adversarial stopping-time distribution can be achieved in polynomial
time. Consequently, our polynomial-time algorithm for adversarial stopping time
also computes an optimal plan among all possible plans.
article_processing_charge: No
author:
- first_name: Krishnendu
full_name: Chatterjee, Krishnendu
id: 2E5DCA20-F248-11E8-B48F-1D18A9856A87
last_name: Chatterjee
orcid: 0000-0002-4561-241X
- first_name: Laurent
full_name: Doyen, Laurent
last_name: Doyen
citation:
ama: 'Chatterjee K, Doyen L. Graph planning with expected finite horizon. In: 34th
Annual ACM/IEEE Symposium on Logic in Computer Science. IEEE; 2019:1-13. doi:10.1109/lics.2019.8785706'
apa: 'Chatterjee, K., & Doyen, L. (2019). Graph planning with expected finite
horizon. In 34th Annual ACM/IEEE Symposium on Logic in Computer Science
(pp. 1–13). Vancouver, BC, Canada: IEEE. https://doi.org/10.1109/lics.2019.8785706'
chicago: Chatterjee, Krishnendu, and Laurent Doyen. “Graph Planning with Expected
Finite Horizon.” In 34th Annual ACM/IEEE Symposium on Logic in Computer Science,
1–13. IEEE, 2019. https://doi.org/10.1109/lics.2019.8785706.
ieee: K. Chatterjee and L. Doyen, “Graph planning with expected finite horizon,”
in 34th Annual ACM/IEEE Symposium on Logic in Computer Science, Vancouver,
BC, Canada, 2019, pp. 1–13.
ista: 'Chatterjee K, Doyen L. 2019. Graph planning with expected finite horizon.
34th Annual ACM/IEEE Symposium on Logic in Computer Science. LICS: Symposium on
Logic in Computer Science, 1–13.'
mla: Chatterjee, Krishnendu, and Laurent Doyen. “Graph Planning with Expected Finite
Horizon.” 34th Annual ACM/IEEE Symposium on Logic in Computer Science,
IEEE, 2019, pp. 1–13, doi:10.1109/lics.2019.8785706.
short: K. Chatterjee, L. Doyen, in:, 34th Annual ACM/IEEE Symposium on Logic in
Computer Science, IEEE, 2019, pp. 1–13.
conference:
end_date: 2019-06-27
location: Vancouver, BC, Canada
name: 'LICS: Symposium on Logic in Computer Science'
start_date: 2019-06-24
date_created: 2020-01-29T16:18:33Z
date_published: 2019-06-01T00:00:00Z
date_updated: 2023-09-07T14:48:11Z
day: '01'
department:
- _id: KrCh
doi: 10.1109/lics.2019.8785706
external_id:
arxiv:
- '1802.03642'
isi:
- '000805002800001'
isi: 1
language:
- iso: eng
main_file_link:
- open_access: '1'
url: https://arxiv.org/abs/1802.03642
month: '06'
oa: 1
oa_version: Preprint
page: 1-13
publication: 34th Annual ACM/IEEE Symposium on Logic in Computer Science
publication_identifier:
isbn:
- '9781728136080'
publication_status: published
publisher: IEEE
quality_controlled: '1'
related_material:
record:
- id: '11402'
relation: later_version
status: public
scopus_import: '1'
status: public
title: Graph planning with expected finite horizon
type: conference
user_id: c635000d-4b10-11ee-a964-aac5a93f6ac1
year: '2019'
...
---
_id: '7451'
abstract:
- lang: eng
text: We prove that the observable telegraph signal accompanying the bistability
in the photon-blockade-breakdown regime of the driven and lossy Jaynes–Cummings
model is the finite-size precursor of what in the thermodynamic limit is a genuine
first-order phase transition. We construct a finite-size scaling of the system
parameters to a well-defined thermodynamic limit, in which the system remains
the same microscopic system, but the telegraph signal becomes macroscopic both
in its timescale and intensity. The existence of such a finite-size scaling completes
and justifies the classification of the photon-blockade-breakdown effect as a
first-order dissipative quantum phase transition.
article_number: '150'
article_processing_charge: No
article_type: original
author:
- first_name: A.
full_name: Vukics, A.
last_name: Vukics
- first_name: A.
full_name: Dombi, A.
last_name: Dombi
- first_name: Johannes M
full_name: Fink, Johannes M
id: 4B591CBA-F248-11E8-B48F-1D18A9856A87
last_name: Fink
orcid: 0000-0001-8112-028X
- first_name: P.
full_name: Domokos, P.
last_name: Domokos
citation:
ama: Vukics A, Dombi A, Fink JM, Domokos P. Finite-size scaling of the photon-blockade
breakdown dissipative quantum phase transition. Quantum. 2019;3. doi:10.22331/q-2019-06-03-150
apa: Vukics, A., Dombi, A., Fink, J. M., & Domokos, P. (2019). Finite-size scaling
of the photon-blockade breakdown dissipative quantum phase transition. Quantum.
Verein zur Förderung des Open Access Publizierens in den Quantenwissenschaften.
https://doi.org/10.22331/q-2019-06-03-150
chicago: Vukics, A., A. Dombi, Johannes M Fink, and P. Domokos. “Finite-Size Scaling
of the Photon-Blockade Breakdown Dissipative Quantum Phase Transition.” Quantum.
Verein zur Förderung des Open Access Publizierens in den Quantenwissenschaften,
2019. https://doi.org/10.22331/q-2019-06-03-150.
ieee: A. Vukics, A. Dombi, J. M. Fink, and P. Domokos, “Finite-size scaling of the
photon-blockade breakdown dissipative quantum phase transition,” Quantum,
vol. 3. Verein zur Förderung des Open Access Publizierens in den Quantenwissenschaften,
2019.
ista: Vukics A, Dombi A, Fink JM, Domokos P. 2019. Finite-size scaling of the photon-blockade
breakdown dissipative quantum phase transition. Quantum. 3, 150.
mla: Vukics, A., et al. “Finite-Size Scaling of the Photon-Blockade Breakdown Dissipative
Quantum Phase Transition.” Quantum, vol. 3, 150, Verein zur Förderung des
Open Access Publizierens in den Quantenwissenschaften, 2019, doi:10.22331/q-2019-06-03-150.
short: A. Vukics, A. Dombi, J.M. Fink, P. Domokos, Quantum 3 (2019).
date_created: 2020-02-05T09:57:57Z
date_published: 2019-06-03T00:00:00Z
date_updated: 2023-09-07T14:57:39Z
day: '03'
ddc:
- '530'
department:
- _id: JoFi
doi: 10.22331/q-2019-06-03-150
external_id:
arxiv:
- '1809.09737'
isi:
- '000469987500004'
file:
- access_level: open_access
checksum: 26b9ba8f0155d183f1ee55295934a17f
content_type: application/pdf
creator: dernst
date_created: 2020-02-11T09:25:23Z
date_updated: 2020-07-14T12:47:58Z
file_id: '7483'
file_name: 2019_Quantum_Vukics.pdf
file_size: 5805248
relation: main_file
file_date_updated: 2020-07-14T12:47:58Z
has_accepted_license: '1'
intvolume: ' 3'
isi: 1
language:
- iso: eng
month: '06'
oa: 1
oa_version: Published Version
publication: Quantum
publication_identifier:
issn:
- 2521-327X
publication_status: published
publisher: Verein zur Förderung des Open Access Publizierens in den Quantenwissenschaften
quality_controlled: '1'
status: public
title: Finite-size scaling of the photon-blockade breakdown dissipative quantum phase
transition
tmp:
image: /images/cc_by.png
legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
short: CC BY (4.0)
type: journal_article
user_id: c635000d-4b10-11ee-a964-aac5a93f6ac1
volume: 3
year: '2019'
...
---
_id: '7468'
abstract:
- lang: eng
text: We present a new proximal bundle method for Maximum-A-Posteriori (MAP) inference
in structured energy minimization problems. The method optimizes a Lagrangean
relaxation of the original energy minimization problem using a multi plane block-coordinate
Frank-Wolfe method that takes advantage of the specific structure of the Lagrangean
decomposition. We show empirically that our method outperforms state-of-the-art
Lagrangean decomposition based algorithms on some challenging Markov Random Field,
multi-label discrete tomography and graph matching problems.
article_number: 11138-11147
article_processing_charge: No
author:
- first_name: Paul
full_name: Swoboda, Paul
id: 446560C6-F248-11E8-B48F-1D18A9856A87
last_name: Swoboda
- first_name: Vladimir
full_name: Kolmogorov, Vladimir
id: 3D50B0BA-F248-11E8-B48F-1D18A9856A87
last_name: Kolmogorov
citation:
ama: 'Swoboda P, Kolmogorov V. Map inference via block-coordinate Frank-Wolfe algorithm.
In: Proceedings of the IEEE Computer Society Conference on Computer Vision
and Pattern Recognition. Vol 2019-June. IEEE; 2019. doi:10.1109/CVPR.2019.01140'
apa: 'Swoboda, P., & Kolmogorov, V. (2019). Map inference via block-coordinate
Frank-Wolfe algorithm. In Proceedings of the IEEE Computer Society Conference
on Computer Vision and Pattern Recognition (Vol. 2019–June). Long Beach, CA,
United States: IEEE. https://doi.org/10.1109/CVPR.2019.01140'
chicago: Swoboda, Paul, and Vladimir Kolmogorov. “Map Inference via Block-Coordinate
Frank-Wolfe Algorithm.” In Proceedings of the IEEE Computer Society Conference
on Computer Vision and Pattern Recognition, Vol. 2019–June. IEEE, 2019. https://doi.org/10.1109/CVPR.2019.01140.
ieee: P. Swoboda and V. Kolmogorov, “Map inference via block-coordinate Frank-Wolfe
algorithm,” in Proceedings of the IEEE Computer Society Conference on Computer
Vision and Pattern Recognition, Long Beach, CA, United States, 2019, vol.
2019–June.
ista: 'Swoboda P, Kolmogorov V. 2019. Map inference via block-coordinate Frank-Wolfe
algorithm. Proceedings of the IEEE Computer Society Conference on Computer Vision
and Pattern Recognition. CVPR: Conference on Computer Vision and Pattern Recognition
vol. 2019–June, 11138–11147.'
mla: Swoboda, Paul, and Vladimir Kolmogorov. “Map Inference via Block-Coordinate
Frank-Wolfe Algorithm.” Proceedings of the IEEE Computer Society Conference
on Computer Vision and Pattern Recognition, vol. 2019–June, 11138–11147, IEEE,
2019, doi:10.1109/CVPR.2019.01140.
short: P. Swoboda, V. Kolmogorov, in:, Proceedings of the IEEE Computer Society
Conference on Computer Vision and Pattern Recognition, IEEE, 2019.
conference:
end_date: 2019-06-20
location: Long Beach, CA, United States
name: 'CVPR: Conference on Computer Vision and Pattern Recognition'
start_date: 2019-06-15
date_created: 2020-02-09T23:00:52Z
date_published: 2019-06-01T00:00:00Z
date_updated: 2023-09-07T14:54:24Z
day: '01'
department:
- _id: VlKo
doi: 10.1109/CVPR.2019.01140
ec_funded: 1
external_id:
arxiv:
- '1806.05049'
isi:
- '000542649304076'
isi: 1
language:
- iso: eng
main_file_link:
- open_access: '1'
url: https://arxiv.org/abs/1806.05049
month: '06'
oa: 1
oa_version: Preprint
project:
- _id: 25FBA906-B435-11E9-9278-68D0E5697425
call_identifier: FP7
grant_number: '616160'
name: 'Discrete Optimization in Computer Vision: Theory and Practice'
publication: Proceedings of the IEEE Computer Society Conference on Computer Vision
and Pattern Recognition
publication_identifier:
isbn:
- '9781728132938'
issn:
- '10636919'
publication_status: published
publisher: IEEE
quality_controlled: '1'
scopus_import: '1'
status: public
title: Map inference via block-coordinate Frank-Wolfe algorithm
type: conference
user_id: c635000d-4b10-11ee-a964-aac5a93f6ac1
volume: 2019-June
year: '2019'
...