--- _id: '14887' abstract: - lang: eng text: 'Episodic memories are encoded by experience-activated neuronal ensembles that remain necessary and sufficient for recall. However, the temporal evolution of memory engrams after initial encoding is unclear. In this study, we employed computational and experimental approaches to examine how the neural composition and selectivity of engrams change with memory consolidation. Our spiking neural network model yielded testable predictions: memories transition from unselective to selective as neurons drop out of and drop into engrams; inhibitory activity during recall is essential for memory selectivity; and inhibitory synaptic plasticity during memory consolidation is critical for engrams to become selective. Using activity-dependent labeling, longitudinal calcium imaging and a combination of optogenetic and chemogenetic manipulations in mouse dentate gyrus, we conducted contextual fear conditioning experiments that supported our model’s predictions. Our results reveal that memory engrams are dynamic and that changes in engram composition mediated by inhibitory plasticity are crucial for the emergence of memory selectivity.' acknowledgement: We thank S. Erisken from Inscopix for helping us establish in vivo one-photon calcium imaging for this work. We thank K. Su at Tsinghua University for assistance with this work. This work was funded by the President’s PhD Scholarship from Imperial College London (D.F.T.), the Wellcome Trust (225412/Z/22/Z) (S.S.), the Biotechnology and Biological Sciences Research Council (BB/N013956/1 and BB/N019008/1) (C.C.), the Wellcome Trust (200790/Z/16/Z) (C.C.), the Simons Foundation (564408) (C.C.) and the Engineering and Physical Sciences Research Council (EP/R035806/1) (CC). The School of Life Sciences and the IDG/McGovern Institute for Brain Research supported Y.Z. The Warren Alpert Distinguished Scholar Award and National Institutes of Health 1K99NS125131-01 supported D.S.R. article_processing_charge: Yes (in subscription journal) article_type: original author: - first_name: Douglas full_name: Feitosa Tomé, Douglas id: 0eed2d40-3d48-11ec-8d38-f789cc2e40b2 last_name: Feitosa Tomé - first_name: Ying full_name: Zhang, Ying last_name: Zhang - first_name: Tomomi full_name: Aida, Tomomi last_name: Aida - first_name: Olivia full_name: Mosto, Olivia last_name: Mosto - first_name: Yifeng full_name: Lu, Yifeng last_name: Lu - first_name: Mandy full_name: Chen, Mandy last_name: Chen - first_name: Sadra full_name: Sadeh, Sadra last_name: Sadeh - first_name: Dheeraj S. full_name: Roy, Dheeraj S. last_name: Roy - first_name: Claudia full_name: Clopath, Claudia last_name: Clopath citation: ama: Feitosa Tomé D, Zhang Y, Aida T, et al. Dynamic and selective engrams emerge with memory consolidation. Nature Neuroscience. 2024. doi:10.1038/s41593-023-01551-w apa: Feitosa Tomé, D., Zhang, Y., Aida, T., Mosto, O., Lu, Y., Chen, M., … Clopath, C. (2024). Dynamic and selective engrams emerge with memory consolidation. Nature Neuroscience. Springer Nature. https://doi.org/10.1038/s41593-023-01551-w chicago: Feitosa Tomé, Douglas, Ying Zhang, Tomomi Aida, Olivia Mosto, Yifeng Lu, Mandy Chen, Sadra Sadeh, Dheeraj S. Roy, and Claudia Clopath. “Dynamic and Selective Engrams Emerge with Memory Consolidation.” Nature Neuroscience. Springer Nature, 2024. https://doi.org/10.1038/s41593-023-01551-w. ieee: D. Feitosa Tomé et al., “Dynamic and selective engrams emerge with memory consolidation,” Nature Neuroscience. Springer Nature, 2024. ista: Feitosa Tomé D, Zhang Y, Aida T, Mosto O, Lu Y, Chen M, Sadeh S, Roy DS, Clopath C. 2024. Dynamic and selective engrams emerge with memory consolidation. Nature Neuroscience. mla: Feitosa Tomé, Douglas, et al. “Dynamic and Selective Engrams Emerge with Memory Consolidation.” Nature Neuroscience, Springer Nature, 2024, doi:10.1038/s41593-023-01551-w. short: D. Feitosa Tomé, Y. Zhang, T. Aida, O. Mosto, Y. Lu, M. Chen, S. Sadeh, D.S. Roy, C. Clopath, Nature Neuroscience (2024). date_created: 2024-01-28T23:01:43Z date_published: 2024-01-19T00:00:00Z date_updated: 2024-01-29T09:22:00Z day: '19' department: - _id: TiVo doi: 10.1038/s41593-023-01551-w external_id: isi: - '001145442300001' isi: 1 language: - iso: eng main_file_link: - open_access: '1' url: https://doi.org/10.1038/s41593-023-01551-w month: '01' oa: 1 oa_version: Published Version publication: Nature Neuroscience publication_identifier: eissn: - 1546-1726 issn: - 1097-6256 publication_status: epub_ahead publisher: Springer Nature quality_controlled: '1' related_material: record: - id: '14892' relation: research_data status: public scopus_import: '1' status: public title: Dynamic and selective engrams emerge with memory consolidation type: journal_article user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87 year: '2024' ... --- _id: '14251' abstract: - lang: eng text: The phytohormone auxin and its directional transport through tissues play a fundamental role in development of higher plants. This polar auxin transport predominantly relies on PIN-FORMED (PIN) auxin exporters. Hence, PIN polarization is crucial for development, but its evolution during the rise of morphological complexity in land plants remains unclear. Here, we performed a cross-species investigation by observing the trafficking and localization of endogenous and exogenous PINs in two bryophytes, Physcomitrium patens and Marchantia polymorpha, and in the flowering plant Arabidopsis thaliana. We confirmed that the GFP fusion did not compromise the auxin export function of all examined PINs by using radioactive auxin export assay and by observing the phenotypic changes in transgenic bryophytes. Endogenous PINs polarize to filamentous apices, while exogenous Arabidopsis PINs distribute symmetrically on the membrane in both bryophytes. In Arabidopsis root epidermis, bryophytic PINs show no defined polarity. Pharmacological interference revealed a strong cytoskeleton dependence of bryophytic but not Arabidopsis PIN polarization. The divergence of PIN polarization and trafficking is also observed within the bryophyte clade and between tissues of individual species. These results collectively reveal a divergence of PIN trafficking and polarity mechanisms throughout land plant evolution and a co-evolution of PIN sequence-based and cell-based polarity mechanisms. acknowledgement: This work was supported by the ERC grant (PR1023ERC02) to H. T. and J. F., and by the ministry of science and technology (grant number 110-2636-B-005-001) to K. J. L. article_number: '100669' article_processing_charge: Yes article_type: original author: - first_name: Han full_name: Tang, Han id: 19BDF720-25A0-11EA-AC6E-928F3DDC885E last_name: Tang orcid: 0000-0001-6152-6637 - first_name: KJ full_name: Lu, KJ last_name: Lu - first_name: Y full_name: Zhang, Y last_name: Zhang - first_name: YL full_name: Cheng, YL last_name: Cheng - first_name: SL full_name: Tu, SL last_name: Tu - first_name: Jiří full_name: Friml, Jiří id: 4159519E-F248-11E8-B48F-1D18A9856A87 last_name: Friml orcid: 0000-0002-8302-7596 citation: ama: Tang H, Lu K, Zhang Y, Cheng Y, Tu S, Friml J. Divergence of trafficking and polarization mechanisms for PIN auxin transporters during land plant evolution. Plant Communications. 2024;5(1). doi:10.1016/j.xplc.2023.100669 apa: Tang, H., Lu, K., Zhang, Y., Cheng, Y., Tu, S., & Friml, J. (2024). Divergence of trafficking and polarization mechanisms for PIN auxin transporters during land plant evolution. Plant Communications. Elsevier. https://doi.org/10.1016/j.xplc.2023.100669 chicago: Tang, Han, KJ Lu, Y Zhang, YL Cheng, SL Tu, and Jiří Friml. “Divergence of Trafficking and Polarization Mechanisms for PIN Auxin Transporters during Land Plant Evolution.” Plant Communications. Elsevier, 2024. https://doi.org/10.1016/j.xplc.2023.100669. ieee: H. Tang, K. Lu, Y. Zhang, Y. Cheng, S. Tu, and J. Friml, “Divergence of trafficking and polarization mechanisms for PIN auxin transporters during land plant evolution,” Plant Communications, vol. 5, no. 1. Elsevier, 2024. ista: Tang H, Lu K, Zhang Y, Cheng Y, Tu S, Friml J. 2024. Divergence of trafficking and polarization mechanisms for PIN auxin transporters during land plant evolution. Plant Communications. 5(1), 100669. mla: Tang, Han, et al. “Divergence of Trafficking and Polarization Mechanisms for PIN Auxin Transporters during Land Plant Evolution.” Plant Communications, vol. 5, no. 1, 100669, Elsevier, 2024, doi:10.1016/j.xplc.2023.100669. short: H. Tang, K. Lu, Y. Zhang, Y. Cheng, S. Tu, J. Friml, Plant Communications 5 (2024). date_created: 2023-09-01T11:32:02Z date_published: 2024-01-08T00:00:00Z date_updated: 2024-01-30T13:00:47Z day: '08' ddc: - '580' department: - _id: JiFr doi: 10.1016/j.xplc.2023.100669 ec_funded: 1 external_id: pmid: - '37528584' file: - access_level: open_access checksum: edbc44c6d4a394d2bf70f92fdbb08f0a content_type: application/pdf creator: dernst date_created: 2024-01-30T12:59:57Z date_updated: 2024-01-30T12:59:57Z file_id: '14911' file_name: 2023_PlantCommunications_Tang.pdf file_size: 2825565 relation: main_file success: 1 file_date_updated: 2024-01-30T12:59:57Z has_accepted_license: '1' intvolume: ' 5' issue: '1' language: - iso: eng license: https://creativecommons.org/licenses/by/4.0/ month: '01' oa: 1 oa_version: Published Version pmid: 1 project: - _id: 261099A6-B435-11E9-9278-68D0E5697425 call_identifier: H2020 grant_number: '742985' name: Tracing Evolution of Auxin Transport and Polarity in Plants publication: Plant Communications publication_identifier: issn: - 2590-3462 publication_status: published publisher: Elsevier quality_controlled: '1' scopus_import: '1' status: public title: Divergence of trafficking and polarization mechanisms for PIN auxin transporters during land plant evolution tmp: image: /images/cc_by.png legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0) short: CC BY (4.0) type: journal_article user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87 volume: 5 year: '2024' ... --- _id: '14886' abstract: - lang: eng text: It is a basic principle that an effect cannot come before the cause. Dispersive relations that follow from this fundamental fact have proven to be an indispensable tool in physics and engineering. They are most powerful in the domain of linear response where they are known as Kramers-Kronig relations. However, when it comes to nonlinear phenomena the implications of causality are much less explored, apart from several notable exceptions. Here in this paper we demonstrate how to apply the dispersive formalism to analyze the ultrafast nonlinear response in the context of the paradigmatic nonlinear Kerr effect. We find that the requirement of causality introduces a noticeable effect even under assumption that Kerr effect is mediated by quasi-instantaneous off-resonant electronic hyperpolarizability. We confirm this by experimentally measuring the time-resolved Kerr dynamics in GaAs by means of a hybrid pump-probe Mach-Zehnder interferometer and demonstrate the presence of an intrinsic lagging between amplitude and phase responses as predicted by dispersive analysis. Our results describe a general property of the time-resolved nonlinear processes thereby highlighting the importance of accounting for dispersive effects in the nonlinear optical processes involving ultrashort pulses. acknowledgement: The work was supported by the Institute of Science and Technology Austria (ISTA). We thank Prof. John M. Dudley, Dr. Ugur Sezer, and Dr. Artem Volosniev for valuable discussions. article_number: '013042' article_processing_charge: Yes article_type: original author: - first_name: Dusan full_name: Lorenc, Dusan id: 40D8A3E6-F248-11E8-B48F-1D18A9856A87 last_name: Lorenc - first_name: Zhanybek full_name: Alpichshev, Zhanybek id: 45E67A2A-F248-11E8-B48F-1D18A9856A87 last_name: Alpichshev orcid: 0000-0002-7183-5203 citation: ama: 'Lorenc D, Alpichshev Z. Dispersive effects in ultrafast nonlinear phenomena: The case of optical Kerr effect. Physical Review Research. 2024;6(1). doi:10.1103/PhysRevResearch.6.013042' apa: 'Lorenc, D., & Alpichshev, Z. (2024). Dispersive effects in ultrafast nonlinear phenomena: The case of optical Kerr effect. Physical Review Research. American Physical Society. https://doi.org/10.1103/PhysRevResearch.6.013042' chicago: 'Lorenc, Dusan, and Zhanybek Alpichshev. “Dispersive Effects in Ultrafast Nonlinear Phenomena: The Case of Optical Kerr Effect.” Physical Review Research. American Physical Society, 2024. https://doi.org/10.1103/PhysRevResearch.6.013042.' ieee: 'D. Lorenc and Z. Alpichshev, “Dispersive effects in ultrafast nonlinear phenomena: The case of optical Kerr effect,” Physical Review Research, vol. 6, no. 1. American Physical Society, 2024.' ista: 'Lorenc D, Alpichshev Z. 2024. Dispersive effects in ultrafast nonlinear phenomena: The case of optical Kerr effect. Physical Review Research. 6(1), 013042.' mla: 'Lorenc, Dusan, and Zhanybek Alpichshev. “Dispersive Effects in Ultrafast Nonlinear Phenomena: The Case of Optical Kerr Effect.” Physical Review Research, vol. 6, no. 1, 013042, American Physical Society, 2024, doi:10.1103/PhysRevResearch.6.013042.' short: D. Lorenc, Z. Alpichshev, Physical Review Research 6 (2024). date_created: 2024-01-28T23:01:42Z date_published: 2024-01-11T00:00:00Z date_updated: 2024-01-31T12:01:16Z day: '11' ddc: - '530' department: - _id: ZhAl doi: 10.1103/PhysRevResearch.6.013042 file: - access_level: open_access checksum: 42d58f93ae74e7f2c4de058ef75ff8b2 content_type: application/pdf creator: dernst date_created: 2024-01-31T11:59:30Z date_updated: 2024-01-31T11:59:30Z file_id: '14918' file_name: 2024_PhysicalReviewResearch_Lorenc.pdf file_size: 2863627 relation: main_file success: 1 file_date_updated: 2024-01-31T11:59:30Z has_accepted_license: '1' intvolume: ' 6' issue: '1' language: - iso: eng month: '01' oa: 1 oa_version: Published Version publication: Physical Review Research publication_identifier: eissn: - 2643-1564 publication_status: published publisher: American Physical Society quality_controlled: '1' scopus_import: '1' status: public title: 'Dispersive effects in ultrafast nonlinear phenomena: The case of optical Kerr effect' tmp: image: /images/cc_by.png legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0) short: CC BY (4.0) type: journal_article user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87 volume: 6 year: '2024' ... --- _id: '14821' alternative_title: - ISTA Thesis article_processing_charge: No author: - first_name: Heloisa full_name: Chiossi, Heloisa id: 2BBA502C-F248-11E8-B48F-1D18A9856A87 last_name: Chiossi citation: ama: Chiossi HSC. Adaptive hierarchical representations in the hippocampus. 2024. doi:10.15479/at:ista:14821 apa: Chiossi, H. S. C. (2024). Adaptive hierarchical representations in the hippocampus. Institute of Science and Technology Austria. https://doi.org/10.15479/at:ista:14821 chicago: Chiossi, Heloisa S. C. “Adaptive Hierarchical Representations in the Hippocampus.” Institute of Science and Technology Austria, 2024. https://doi.org/10.15479/at:ista:14821. ieee: H. S. C. Chiossi, “Adaptive hierarchical representations in the hippocampus,” Institute of Science and Technology Austria, 2024. ista: Chiossi HSC. 2024. Adaptive hierarchical representations in the hippocampus. Institute of Science and Technology Austria. mla: Chiossi, Heloisa S. C. Adaptive Hierarchical Representations in the Hippocampus. Institute of Science and Technology Austria, 2024, doi:10.15479/at:ista:14821. short: H.S.C. Chiossi, Adaptive Hierarchical Representations in the Hippocampus, Institute of Science and Technology Austria, 2024. date_created: 2024-01-16T14:25:21Z date_published: 2024-01-19T00:00:00Z date_updated: 2024-02-01T09:50:29Z day: '19' ddc: - '570' degree_awarded: PhD department: - _id: GradSch - _id: JoCs doi: 10.15479/at:ista:14821 ec_funded: 1 file: - access_level: closed checksum: d3fa3de1abd5af5204c13e9d55375615 content_type: application/vnd.openxmlformats-officedocument.wordprocessingml.document creator: hchiossi date_created: 2024-01-19T11:04:05Z date_updated: 2024-01-19T11:04:05Z file_id: '14838' file_name: PhD_Thesis_190124.docx file_size: 8656268 relation: source_file - access_level: closed checksum: 13adc8dcfb5b6b18107f89f0a98fa8bd content_type: application/pdf creator: hchiossi date_created: 2024-01-19T11:03:59Z date_updated: 2024-01-19T11:03:59Z embargo: 2025-01-19 embargo_to: open_access file_id: '14839' file_name: PhD_Thesis_190124.pdf file_size: 6567275 relation: main_file file_date_updated: 2024-01-19T11:04:05Z has_accepted_license: '1' language: - iso: eng month: '01' oa_version: Published Version page: '89' project: - _id: 2564DBCA-B435-11E9-9278-68D0E5697425 call_identifier: H2020 grant_number: '665385' name: International IST Doctoral Program publication_identifier: issn: - 2663 - 337X publication_status: published publisher: Institute of Science and Technology Austria status: public supervisor: - first_name: Jozsef L full_name: Csicsvari, Jozsef L id: 3FA14672-F248-11E8-B48F-1D18A9856A87 last_name: Csicsvari orcid: 0000-0002-5193-4036 title: Adaptive hierarchical representations in the hippocampus type: dissertation user_id: 8b945eb4-e2f2-11eb-945a-df72226e66a9 year: '2024' ... --- _id: '14901' abstract: - lang: eng text: Global services like navigation, communication, and Earth observation have increased dramatically in the 21st century due to advances in outer space industries. But as orbits become increasingly crowded with both satellites and inevitable space debris pollution, continued operations become endangered by the heightened risks of debris collisions in orbit. Kessler Syndrome is the term for when a critical threshold of orbiting debris triggers a runaway positive feedback loop of debris collisions, creating debris congestion that can render orbits unusable. As this potential tipping point becomes more widely recognized, there have been renewed calls for debris mitigation and removal. Here, we combine complex systems and social-ecological systems approaches to study how these efforts may affect space debris accumulation and the likelihood of reaching Kessler Syndrome. Specifically, we model how debris levels are affected by future launch rates, cleanup activities, and collisions between extant debris. We contextualize and interpret our dynamic model within a discussion of existing space debris governance and other social, economic, and geopolitical factors that may influence effective collective management of the orbital commons. In line with previous studies, our model finds that debris congestion may be reached in less than 200 years, though a holistic management strategy combining removal and mitigation actions can avoid such outcomes while continuing space activities. Moreover, although active debris removal may be particularly effective, the current lack of market and governance support may impede its implementation. Research into these critical dynamics and the multi-faceted variables that influence debris outcomes can support policymakers in curating impactful governance strategies and realistic transition pathways to sustaining debris-free orbits. Overall, our study is useful for communicating about space debris sustainability in policy and education settings by providing an exploration of policy portfolio options supported by a simple and clear social-ecological modeling approach. acknowledgement: The authors would like to thank the special issue co-editors, Marco Janssen and Xiao-Shan Yap, and the anonymous reviewers for their comments that helped improve the manuscript. The paper also benefited from suggestions by other author participants in this special issue. We would also like to thank the 2022 Santa Fe Institute Complex Systems Summer School for providing space to initiate this study. article_processing_charge: Yes article_type: original author: - first_name: Keiko full_name: Nomura, Keiko last_name: Nomura - first_name: Simon full_name: Rella, Simon id: B4765ACA-AA38-11E9-AC9A-0930E6697425 last_name: Rella - first_name: Haily full_name: Merritt, Haily last_name: Merritt - first_name: Mathieu full_name: Baltussen, Mathieu last_name: Baltussen - first_name: Darcy full_name: Bird, Darcy last_name: Bird - first_name: Annika full_name: Tjuka, Annika last_name: Tjuka - first_name: Dan full_name: Falk, Dan last_name: Falk citation: ama: Nomura K, Rella S, Merritt H, et al. Tipping points of space debris in low earth orbit. International Journal of the Commons. 2024;18(1). doi:10.5334/ijc.1275 apa: Nomura, K., Rella, S., Merritt, H., Baltussen, M., Bird, D., Tjuka, A., & Falk, D. (2024). Tipping points of space debris in low earth orbit. International Journal of the Commons. Ubiquity Press. https://doi.org/10.5334/ijc.1275 chicago: Nomura, Keiko, Simon Rella, Haily Merritt, Mathieu Baltussen, Darcy Bird, Annika Tjuka, and Dan Falk. “Tipping Points of Space Debris in Low Earth Orbit.” International Journal of the Commons. Ubiquity Press, 2024. https://doi.org/10.5334/ijc.1275. ieee: K. Nomura et al., “Tipping points of space debris in low earth orbit,” International Journal of the Commons, vol. 18, no. 1. Ubiquity Press, 2024. ista: Nomura K, Rella S, Merritt H, Baltussen M, Bird D, Tjuka A, Falk D. 2024. Tipping points of space debris in low earth orbit. International Journal of the Commons. 18(1). mla: Nomura, Keiko, et al. “Tipping Points of Space Debris in Low Earth Orbit.” International Journal of the Commons, vol. 18, no. 1, Ubiquity Press, 2024, doi:10.5334/ijc.1275. short: K. Nomura, S. Rella, H. Merritt, M. Baltussen, D. Bird, A. Tjuka, D. Falk, International Journal of the Commons 18 (2024). date_created: 2024-01-30T11:58:02Z date_published: 2024-01-11T00:00:00Z date_updated: 2024-02-05T10:10:27Z day: '11' ddc: - '550' department: - _id: GradSch - _id: GaTk doi: 10.5334/ijc.1275 file: - access_level: open_access checksum: b80ebc889033c365d8f8c05a0c655382 content_type: application/pdf creator: dernst date_created: 2024-02-05T10:06:35Z date_updated: 2024-02-05T10:06:35Z file_id: '14939' file_name: 2023_IntJourCommons_Nomura.pdf file_size: 1305786 relation: main_file success: 1 file_date_updated: 2024-02-05T10:06:35Z has_accepted_license: '1' intvolume: ' 18' issue: '1' keyword: - Sociology and Political Science language: - iso: eng month: '01' oa: 1 oa_version: Published Version publication: International Journal of the Commons publication_identifier: issn: - 1875-0281 publication_status: published publisher: Ubiquity Press quality_controlled: '1' scopus_import: '1' status: public title: Tipping points of space debris in low earth orbit tmp: image: /images/cc_by.png legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0) short: CC BY (4.0) type: journal_article user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87 volume: 18 year: '2024' ... --- _id: '14884' abstract: - lang: eng text: We perform a stochastic homogenization analysis for composite materials exhibiting a random microstructure. Under the assumptions of stationarity and ergodicity, we characterize the Gamma-limit of a micromagnetic energy functional defined on magnetizations taking value in the unit sphere and including both symmetric and antisymmetric exchange contributions. This Gamma-limit corresponds to a micromagnetic energy functional with homogeneous coefficients. We provide explicit formulas for the effective magnetic properties of the composite material in terms of homogenization correctors. Additionally, the variational analysis of the two exchange energy terms is performed in the more general setting of functionals defined on manifold-valued maps with Sobolev regularity, in the case in which the target manifold is a bounded, orientable smooth surface with tubular neighborhood of uniform thickness. Eventually, we present an explicit characterization of minimizers of the effective exchange in the case of magnetic multilayers, providing quantitative evidence of Dzyaloshinskii’s predictions on the emergence of helical structures in composite ferromagnetic materials with stochastic microstructure. acknowledgement: All authors acknowledge support of the Austrian Science Fund (FWF) through the SFB project F65. The research of E. Davoli and L. D’Elia has additionally been supported by the FWF through grants V662, Y1292, and P35359, as well as from OeAD through the WTZ grant CZ09/2023. article_number: '30' article_processing_charge: No article_type: original author: - first_name: Elisa full_name: Davoli, Elisa last_name: Davoli - first_name: Lorenza full_name: D’Elia, Lorenza last_name: D’Elia - first_name: Jonas full_name: Ingmanns, Jonas id: 71523d30-15b2-11ec-abd3-f80aa909d6b0 last_name: Ingmanns citation: ama: Davoli E, D’Elia L, Ingmanns J. Stochastic homogenization of micromagnetic energies and emergence of magnetic skyrmions. Journal of Nonlinear Science. 2024;34(2). doi:10.1007/s00332-023-10005-3 apa: Davoli, E., D’Elia, L., & Ingmanns, J. (2024). Stochastic homogenization of micromagnetic energies and emergence of magnetic skyrmions. Journal of Nonlinear Science. Springer Nature. https://doi.org/10.1007/s00332-023-10005-3 chicago: Davoli, Elisa, Lorenza D’Elia, and Jonas Ingmanns. “Stochastic Homogenization of Micromagnetic Energies and Emergence of Magnetic Skyrmions.” Journal of Nonlinear Science. Springer Nature, 2024. https://doi.org/10.1007/s00332-023-10005-3. ieee: E. Davoli, L. D’Elia, and J. Ingmanns, “Stochastic homogenization of micromagnetic energies and emergence of magnetic skyrmions,” Journal of Nonlinear Science, vol. 34, no. 2. Springer Nature, 2024. ista: Davoli E, D’Elia L, Ingmanns J. 2024. Stochastic homogenization of micromagnetic energies and emergence of magnetic skyrmions. Journal of Nonlinear Science. 34(2), 30. mla: Davoli, Elisa, et al. “Stochastic Homogenization of Micromagnetic Energies and Emergence of Magnetic Skyrmions.” Journal of Nonlinear Science, vol. 34, no. 2, 30, Springer Nature, 2024, doi:10.1007/s00332-023-10005-3. short: E. Davoli, L. D’Elia, J. Ingmanns, Journal of Nonlinear Science 34 (2024). date_created: 2024-01-28T23:01:42Z date_published: 2024-01-23T00:00:00Z date_updated: 2024-02-05T08:54:44Z day: '23' department: - _id: JuFi doi: 10.1007/s00332-023-10005-3 external_id: arxiv: - '2306.05151' intvolume: ' 34' issue: '2' language: - iso: eng main_file_link: - open_access: '1' url: https://doi.org/10.48550/arXiv.2306.05151 month: '01' oa: 1 oa_version: Preprint project: - _id: fc31cba2-9c52-11eb-aca3-ff467d239cd2 grant_number: F6504 name: Taming Complexity in Partial Differential Systems publication: Journal of Nonlinear Science publication_identifier: eissn: - 1432-1467 issn: - 0938-8974 publication_status: epub_ahead publisher: Springer Nature quality_controlled: '1' scopus_import: '1' status: public title: Stochastic homogenization of micromagnetic energies and emergence of magnetic skyrmions type: journal_article user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87 volume: 34 year: '2024' ... --- _id: '14933' abstract: - lang: eng text: Centrioles are part of centrosomes and cilia, which are microtubule organising centres (MTOC) with diverse functions. Despite their stability, centrioles can disappear during differentiation, such as in oocytes, but little is known about the regulation of their structural integrity. Our previous research revealed that the pericentriolar material (PCM) that surrounds centrioles and its recruiter, Polo kinase, are downregulated in oogenesis and sufficient for maintaining both centrosome structural integrity and MTOC activity. We now show that the expression of specific components of the centriole cartwheel and wall, including ANA1/CEP295, is essential for maintaining centrosome integrity. We find that Polo kinase requires ANA1 to promote centriole stability in cultured cells and eggs. In addition, ANA1 expression prevents the loss of centrioles observed upon PCM-downregulation. However, the centrioles maintained by overexpressing and tethering ANA1 are inactive, unlike the MTOCs observed upon tethering Polo kinase. These findings demonstrate that several centriole components are needed to maintain centrosome structure. Our study also highlights that centrioles are more dynamic than previously believed, with their structural stability relying on the continuous expression of multiple components. acknowledgement: We thank all members of the Cell Cycle and Regulation Lab for the discussions and for the critical reading of the manuscript. We thank Tomer Avidor-Reiss (University of Toledo, Toledo, OH), Daniel St. Johnston (The Gurdon Institute, Cambridge, UK), David Glover (University of Cambridge, Cambridge, UK), Jingyan Fu (Agricultural University, Beijing, China) Jordan Raff (University of Oxford, Oxford, UK) and Timothy Megraw (Florida State University, Tallahassee, FL) for sharing tools. We acknowledge the technical support of Instituto Gulbenkian de Ciência (IGC)‘s Advanced Imaging Facility, in particular Gabriel Martins, Nuno Pimpão Martins and José Marques. We also thank Tiago Paixão from the IGC’s Quantitative & Digital Science Unit and Marco Louro from the CCR lab for the support provided on statistical analysis. IGC’s Advanced Imaging Facility (AIF-UIC) is supported by the national Portuguese funding ref# PPBI-POCI-01-0145-FEDER -022122. We thank the IGC’s Fly Facility, supported by CONGENTO (LISBOA-01-0145-FEDER-022170). This work was supported by an ERC grant (ERC-2015-CoG-683258) awarded to MBD and a grant from the Portuguese Research Council (FCT) awarded to APM (PTDC/BIA-BID/32225/2017). article_processing_charge: Yes (in subscription journal) article_type: original author: - first_name: Ana full_name: Pimenta-Marques, Ana last_name: Pimenta-Marques - first_name: Tania full_name: Perestrelo, Tania last_name: Perestrelo - first_name: Patricia full_name: Dos Reis Rodrigues, Patricia id: 26E95904-5160-11E9-9C0B-C5B0DC97E90F last_name: Dos Reis Rodrigues orcid: 0000-0003-1681-508X - first_name: Paulo full_name: Duarte, Paulo last_name: Duarte - first_name: Ana full_name: Ferreira-Silva, Ana last_name: Ferreira-Silva - first_name: Mariana full_name: Lince-Faria, Mariana last_name: Lince-Faria - first_name: Mónica full_name: Bettencourt-Dias, Mónica last_name: Bettencourt-Dias citation: ama: Pimenta-Marques A, Perestrelo T, Dos Reis Rodrigues P, et al. Ana1/CEP295 is an essential player in the centrosome maintenance program regulated by Polo kinase and the PCM. EMBO reports. 2024;25(1):102-127. doi:10.1038/s44319-023-00020-6 apa: Pimenta-Marques, A., Perestrelo, T., Dos Reis Rodrigues, P., Duarte, P., Ferreira-Silva, A., Lince-Faria, M., & Bettencourt-Dias, M. (2024). Ana1/CEP295 is an essential player in the centrosome maintenance program regulated by Polo kinase and the PCM. EMBO Reports. Embo Press. https://doi.org/10.1038/s44319-023-00020-6 chicago: Pimenta-Marques, Ana, Tania Perestrelo, Patricia Dos Reis Rodrigues, Paulo Duarte, Ana Ferreira-Silva, Mariana Lince-Faria, and Mónica Bettencourt-Dias. “Ana1/CEP295 Is an Essential Player in the Centrosome Maintenance Program Regulated by Polo Kinase and the PCM.” EMBO Reports. Embo Press, 2024. https://doi.org/10.1038/s44319-023-00020-6. ieee: A. Pimenta-Marques et al., “Ana1/CEP295 is an essential player in the centrosome maintenance program regulated by Polo kinase and the PCM,” EMBO reports, vol. 25, no. 1. Embo Press, pp. 102–127, 2024. ista: Pimenta-Marques A, Perestrelo T, Dos Reis Rodrigues P, Duarte P, Ferreira-Silva A, Lince-Faria M, Bettencourt-Dias M. 2024. Ana1/CEP295 is an essential player in the centrosome maintenance program regulated by Polo kinase and the PCM. EMBO reports. 25(1), 102–127. mla: Pimenta-Marques, Ana, et al. “Ana1/CEP295 Is an Essential Player in the Centrosome Maintenance Program Regulated by Polo Kinase and the PCM.” EMBO Reports, vol. 25, no. 1, Embo Press, 2024, pp. 102–27, doi:10.1038/s44319-023-00020-6. short: A. Pimenta-Marques, T. Perestrelo, P. Dos Reis Rodrigues, P. Duarte, A. Ferreira-Silva, M. Lince-Faria, M. Bettencourt-Dias, EMBO Reports 25 (2024) 102–127. date_created: 2024-02-04T23:00:53Z date_published: 2024-01-10T00:00:00Z date_updated: 2024-02-05T12:37:07Z day: '10' ddc: - '570' department: - _id: MiSi doi: 10.1038/s44319-023-00020-6 file: - access_level: open_access checksum: 53c3ef43d9bd6d7bff3ffcf57d763cac content_type: application/pdf creator: dernst date_created: 2024-02-05T12:35:03Z date_updated: 2024-02-05T12:35:03Z file_id: '14941' file_name: 2023_EmboReports_PimentaMarques.pdf file_size: 9645056 relation: main_file success: 1 file_date_updated: 2024-02-05T12:35:03Z has_accepted_license: '1' intvolume: ' 25' issue: '1' language: - iso: eng month: '01' oa: 1 oa_version: Published Version page: 102-127 publication: EMBO reports publication_identifier: eissn: - 1469-3178 publication_status: published publisher: Embo Press quality_controlled: '1' scopus_import: '1' status: public title: Ana1/CEP295 is an essential player in the centrosome maintenance program regulated by Polo kinase and the PCM tmp: image: /images/cc_by.png legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0) short: CC BY (4.0) type: journal_article user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87 volume: 25 year: '2024' ... --- _id: '14932' abstract: - lang: eng text: The huge antlers of the extinct Irish elk have invited evolutionary speculation since Darwin. In the 1970s, Stephen Jay Gould presented the first extensive data on antler size in the Irish elk and combined these with comparative data from other deer to test the hypothesis that the gigantic antlers were the outcome of a positive allometry that constrained large-bodied deer to have proportionally even larger antlers. He concluded that the Irish elk had antlers as predicted for its size and interpreted this within his emerging framework of developmental constraints as an explanatory factor in evolution. Here we reanalyze antler allometry based on new morphometric data for 57 taxa of the family Cervidae. We also present a new phylogeny for the Cervidae, which we use for comparative analyses. In contrast to Gould, we find that the antlers of Irish elk were larger than predicted from the allometry within the true deer, Cervini, as analyzed by Gould, but follow the allometry across Cervidae as a whole. After dissecting the discrepancy, we reject the allometric-constraint hypothesis because, contrary to Gould, we find no similarity between static and evolutionary allometries, and because we document extensive non-allometric evolution of antler size across the Cervidae. acknowledgement: "Open access funding provided by University of Oslo (incl Oslo University Hospital).\r\nWe thank Adrian Lister, Louis Tomsett, Roberto Portela Miguez and Roula Pappa (NHMUK), Brian O'Toole and Eileen Westwig (AMNH), Daniela Kalthoff (NHRM), Alexander Bibl and Zachos Frank (NHMW), Darrin Lunde and John Ososky (NMNH), Matthew Parkes and Nigel Monaghan (NMI), Elizabetta Cioppi and Luca Bellucci (IGF), and Yoshihiro Tanaka and Hiroyuki Taruno (OMNH), who helped us in obtaining the museum data, and a special thanks to Jørgen Sikkeland (NTNU NHM) for assistance in obtaining the ontogenetic data for the red deer. We thank Olja Toljagic and Kjetil L. Voje for discussions, Ayumu Tsuboi for assistance with data collection, and Jean-Michel Gaillard and the anonymous reviewers for comments on the manuscript. We thank the Centre of Advanced Study (CAS) at the Norwegian Academy of Sciences and Letters for hosting us during the academic year of 2019/2020 when much of the analysis and writing were done. MT was funded by JSPS Research Fellowship for Young Scientists (201603238)." article_processing_charge: Yes (via OA deal) article_type: original author: - first_name: Masahito full_name: Tsuboi, Masahito last_name: Tsuboi - first_name: Bjørn Tore full_name: Kopperud, Bjørn Tore last_name: Kopperud - first_name: Michael full_name: Matschiner, Michael last_name: Matschiner - first_name: Mark full_name: Grabowski, Mark last_name: Grabowski - first_name: Chrsitine full_name: Syrowatka, Chrsitine id: 205ffb76-7fe7-11eb-aa17-958bd11b99ad last_name: Syrowatka - first_name: Christophe full_name: Pélabon, Christophe last_name: Pélabon - first_name: Thomas F. full_name: Hansen, Thomas F. last_name: Hansen citation: ama: Tsuboi M, Kopperud BT, Matschiner M, et al. Antler allometry, the Irish elk and Gould revisited. Evolutionary Biology. 2024. doi:10.1007/s11692-023-09624-1 apa: Tsuboi, M., Kopperud, B. T., Matschiner, M., Grabowski, M., Syrowatka, C., Pélabon, C., & Hansen, T. F. (2024). Antler allometry, the Irish elk and Gould revisited. Evolutionary Biology. Springer Nature. https://doi.org/10.1007/s11692-023-09624-1 chicago: Tsuboi, Masahito, Bjørn Tore Kopperud, Michael Matschiner, Mark Grabowski, Chrsitine Syrowatka, Christophe Pélabon, and Thomas F. Hansen. “Antler Allometry, the Irish Elk and Gould Revisited.” Evolutionary Biology. Springer Nature, 2024. https://doi.org/10.1007/s11692-023-09624-1. ieee: M. Tsuboi et al., “Antler allometry, the Irish elk and Gould revisited,” Evolutionary Biology. Springer Nature, 2024. ista: Tsuboi M, Kopperud BT, Matschiner M, Grabowski M, Syrowatka C, Pélabon C, Hansen TF. 2024. Antler allometry, the Irish elk and Gould revisited. Evolutionary Biology. mla: Tsuboi, Masahito, et al. “Antler Allometry, the Irish Elk and Gould Revisited.” Evolutionary Biology, Springer Nature, 2024, doi:10.1007/s11692-023-09624-1. short: M. Tsuboi, B.T. Kopperud, M. Matschiner, M. Grabowski, C. Syrowatka, C. Pélabon, T.F. Hansen, Evolutionary Biology (2024). date_created: 2024-02-04T23:00:53Z date_published: 2024-01-29T00:00:00Z date_updated: 2024-02-05T12:43:58Z day: '29' department: - _id: MaRo doi: 10.1007/s11692-023-09624-1 language: - iso: eng main_file_link: - open_access: '1' url: https://doi.org/10.1007/s11692-023-09624-1 month: '01' oa: 1 oa_version: Published Version publication: Evolutionary Biology publication_identifier: eissn: - 1934-2845 issn: - 0071-3260 publication_status: epub_ahead publisher: Springer Nature quality_controlled: '1' scopus_import: '1' status: public title: Antler allometry, the Irish elk and Gould revisited type: journal_article user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87 year: '2024' ... --- _id: '14934' abstract: - lang: eng text: "We study random perturbations of a Riemannian manifold (M, g) by means of so-called\r\nFractional Gaussian Fields, which are defined intrinsically by the given manifold. The fields\r\nh• : ω \x02→ hω will act on the manifold via the conformal transformation g \x02→ gω := e2hω g.\r\nOur focus will be on the regular case with Hurst parameter H > 0, the critical case H = 0\r\nbeing the celebrated Liouville geometry in two dimensions. We want to understand how basic\r\ngeometric and functional-analytic quantities like diameter, volume, heat kernel, Brownian\r\nmotion, spectral bound, or spectral gap change under the influence of the noise. And if so, is\r\nit possible to quantify these dependencies in terms of key parameters of the noise? Another\r\ngoal is to define and analyze in detail the Fractional Gaussian Fields on a general Riemannian\r\nmanifold, a fascinating object of independent interest." acknowledgement: "The authors would like to thank Matthias Erbar and Ronan Herry for valuable discussions on this project. They are also grateful to Nathanaël Berestycki, and Fabrice Baudoin for respectively pointing out the references [7], and [6, 24], and to Julien Fageot and Thomas Letendre for pointing out a mistake in a previous version of the proof of Proposition 3.10. The authors feel very much indebted to an anonymous reviewer for his/her careful reading and the many valuable suggestions that have significantly contributed to the improvement of the paper. L.D.S. gratefully acknowledges financial support by the Deutsche Forschungsgemeinschaft through CRC 1060 as well as through SPP 2265, and by the Austrian Science Fund (FWF) grant F65 at Institute of Science and Technology Austria. This research was funded in whole or in part by the Austrian Science Fund (FWF) ESPRIT 208. For the purpose of open access, the authors have applied a CC BY public copyright licence to any Author Accepted Manuscript version arising from this submission. E.K. and K.-T.S. gratefully acknowledge funding by the Deutsche Forschungsgemeinschaft through the Hausdorff Center for Mathematics and through CRC 1060 as well as through SPP 2265.\r\nOpen Access funding enabled and organized by Projekt DEAL." article_processing_charge: Yes (via OA deal) article_type: original author: - first_name: Lorenzo full_name: Dello Schiavo, Lorenzo id: ECEBF480-9E4F-11EA-B557-B0823DDC885E last_name: Dello Schiavo orcid: 0000-0002-9881-6870 - first_name: Eva full_name: Kopfer, Eva last_name: Kopfer - first_name: Karl Theodor full_name: Sturm, Karl Theodor last_name: Sturm citation: ama: Dello Schiavo L, Kopfer E, Sturm KT. A discovery tour in random Riemannian geometry. Potential Analysis. 2024. doi:10.1007/s11118-023-10118-0 apa: Dello Schiavo, L., Kopfer, E., & Sturm, K. T. (2024). A discovery tour in random Riemannian geometry. Potential Analysis. Springer Nature. https://doi.org/10.1007/s11118-023-10118-0 chicago: Dello Schiavo, Lorenzo, Eva Kopfer, and Karl Theodor Sturm. “A Discovery Tour in Random Riemannian Geometry.” Potential Analysis. Springer Nature, 2024. https://doi.org/10.1007/s11118-023-10118-0. ieee: L. Dello Schiavo, E. Kopfer, and K. T. Sturm, “A discovery tour in random Riemannian geometry,” Potential Analysis. Springer Nature, 2024. ista: Dello Schiavo L, Kopfer E, Sturm KT. 2024. A discovery tour in random Riemannian geometry. Potential Analysis. mla: Dello Schiavo, Lorenzo, et al. “A Discovery Tour in Random Riemannian Geometry.” Potential Analysis, Springer Nature, 2024, doi:10.1007/s11118-023-10118-0. short: L. Dello Schiavo, E. Kopfer, K.T. Sturm, Potential Analysis (2024). date_created: 2024-02-04T23:00:54Z date_published: 2024-01-26T00:00:00Z date_updated: 2024-02-05T13:04:23Z day: '26' department: - _id: JaMa doi: 10.1007/s11118-023-10118-0 language: - iso: eng main_file_link: - open_access: '1' url: https://doi.org/10.1007/s11118-023-10118-0 month: '01' oa: 1 oa_version: Published Version project: - _id: fc31cba2-9c52-11eb-aca3-ff467d239cd2 grant_number: F6504 name: Taming Complexity in Partial Differential Systems publication: Potential Analysis publication_identifier: eissn: - 1572-929X issn: - 0926-2601 publication_status: epub_ahead publisher: Springer Nature quality_controlled: '1' scopus_import: '1' status: public title: A discovery tour in random Riemannian geometry type: journal_article user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87 year: '2024' ... --- _id: '12312' abstract: - lang: eng text: "Let $\\ell$ be a prime number. We classify the subgroups $G$ of $\\operatorname{Sp}_4(\\mathbb{F}_\\ell)$ and $\\operatorname{GSp}_4(\\mathbb{F}_\\ell)$ that act irreducibly on $\\mathbb{F}_\\ell^4$, but such that every element of $G$ fixes an $\\mathbb{F}_\\ell$-vector subspace of dimension 1. We use this classification to prove that the local-global principle for isogenies of degree $\\ell$ between abelian surfaces over number fields holds in many cases -- in particular, whenever the abelian surface has non-trivial endomorphisms and $\\ell$ is large enough with respect to the field of definition. Finally, we prove that there exist arbitrarily large primes $\\ell$ for which some abelian surface\r\n$A/\\mathbb{Q}$ fails the local-global principle for isogenies of degree $\\ell$." acknowledgement: "It is a pleasure to thank Samuele Anni for his interest in this project and for several discussions on the topic of this paper, which led in particular to Remark 6.30 and to a better understanding of the difficulties with [6]. We also thank John Cullinan for correspondence about [6] and Barinder Banwait for his many insightful comments on the first version of this paper. Finally, we thank the referee for their thorough reading of the manuscript.\r\nOpen access funding provided by Università di Pisa within the CRUI-CARE Agreement. The authors have been partially supported by MIUR (Italy) through PRIN 2017 “Geometric, algebraic and analytic methods in arithmetic\" and PRIN 2022 “Semiabelian varieties, Galois representations and related Diophantine problems\", and by the University of Pisa through PRA 2018-19 and 2022 “Spazi di moduli, rappresentazioni e strutture combinatorie\". The first author is a member of the INdAM group GNSAGA." article_number: '18' article_processing_charge: Yes (via OA deal) article_type: original author: - first_name: Davide full_name: Lombardo, Davide last_name: Lombardo - first_name: Matteo full_name: Verzobio, Matteo id: 7aa8f170-131e-11ed-88e1-a9efd01027cb last_name: Verzobio orcid: 0000-0002-0854-0306 citation: ama: Lombardo D, Verzobio M. On the local-global principle for isogenies of abelian surfaces. Selecta Mathematica. 2024;30(2). doi:10.1007/s00029-023-00908-0 apa: Lombardo, D., & Verzobio, M. (2024). On the local-global principle for isogenies of abelian surfaces. Selecta Mathematica. Springer Nature. https://doi.org/10.1007/s00029-023-00908-0 chicago: Lombardo, Davide, and Matteo Verzobio. “On the Local-Global Principle for Isogenies of Abelian Surfaces.” Selecta Mathematica. Springer Nature, 2024. https://doi.org/10.1007/s00029-023-00908-0. ieee: D. Lombardo and M. Verzobio, “On the local-global principle for isogenies of abelian surfaces,” Selecta Mathematica, vol. 30, no. 2. Springer Nature, 2024. ista: Lombardo D, Verzobio M. 2024. On the local-global principle for isogenies of abelian surfaces. Selecta Mathematica. 30(2), 18. mla: Lombardo, Davide, and Matteo Verzobio. “On the Local-Global Principle for Isogenies of Abelian Surfaces.” Selecta Mathematica, vol. 30, no. 2, 18, Springer Nature, 2024, doi:10.1007/s00029-023-00908-0. short: D. Lombardo, M. Verzobio, Selecta Mathematica 30 (2024). date_created: 2023-01-16T11:45:53Z date_published: 2024-01-26T00:00:00Z date_updated: 2024-02-05T12:25:00Z day: '26' department: - _id: TiBr doi: 10.1007/s00029-023-00908-0 external_id: arxiv: - '2206.15240' intvolume: ' 30' issue: '2' language: - iso: eng main_file_link: - open_access: '1' url: https://arxiv.org/abs/2206.15240 month: '01' oa: 1 oa_version: Preprint publication: Selecta Mathematica publication_identifier: eissn: - 1420-9020 issn: - 1022-1824 publication_status: epub_ahead publisher: Springer Nature quality_controlled: '1' scopus_import: '1' status: public title: On the local-global principle for isogenies of abelian surfaces type: journal_article user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87 volume: 30 year: '2024' ...