Please note that LibreCat no longer supports Internet Explorer versions 8 or 9 (or earlier).
We recommend upgrading to the latest Internet Explorer, Google Chrome, or Firefox.
27 Publications
2021 | Journal Article | IST-REx-ID: 8993
Naphthylphthalamic acid associates with and inhibits PIN auxin transporters
L. Abas, M. Kolb, J. Stadlmann, D.P. Janacek, K. Lukic, C. Schwechheimer, L.A. Sazanov, L. Mach, J. Friml, U.Z. Hammes, PNAS 118 (2021).
View
| DOI
| PubMed | Europe PMC
L. Abas, M. Kolb, J. Stadlmann, D.P. Janacek, K. Lukic, C. Schwechheimer, L.A. Sazanov, L. Mach, J. Friml, U.Z. Hammes, PNAS 118 (2021).
2020 | Journal Article | IST-REx-ID: 8284 | 
Structure and mechanism of the Mrp complex, an ancient cation/proton antiporter
J. Steiner, L.A. Sazanov, ELife 9 (2020).
View
| Files available
| DOI
| PubMed | Europe PMC
J. Steiner, L.A. Sazanov, ELife 9 (2020).
2020 | Journal Article | IST-REx-ID: 8318 |
Key role of quinone in the mechanism of respiratory complex I
J. Gutierrez-Fernandez, K. Kaszuba, G.S. Minhas, R. Baradaran, M. Tambalo, D.T. Gallagher, L.A. Sazanov, Nature Communications 11 (2020).
View
| Files available
| DOI
| PubMed | Europe PMC
J. Gutierrez-Fernandez, K. Kaszuba, G.S. Minhas, R. Baradaran, M. Tambalo, D.T. Gallagher, L.A. Sazanov, Nature Communications 11 (2020).
2020 | Thesis | IST-REx-ID: 8340
Molecular mechanisms of mitochondrial redox-coupled proton pumping enzymes
D. Kampjut, Molecular Mechanisms of Mitochondrial Redox-Coupled Proton Pumping Enzymes, IST Austria, 2020.
View
| Files available
| DOI
D. Kampjut, Molecular Mechanisms of Mitochondrial Redox-Coupled Proton Pumping Enzymes, IST Austria, 2020.
2020 | Thesis | IST-REx-ID: 8353
Biochemical and structural investigation of the Mrp antiporter, an ancestor of complex I
J. Steiner, Biochemical and Structural Investigation of the Mrp Antiporter, an Ancestor of Complex I, IST Austria, 2020.
View
| Files available
| DOI
J. Steiner, Biochemical and Structural Investigation of the Mrp Antiporter, an Ancestor of Complex I, IST Austria, 2020.
2020 | Journal Article | IST-REx-ID: 8579 |
Cu homeostasis in bacteria: The ins and outs
A. Andrei, Y. Öztürk, B. Khalfaoui-Hassani, J. Rauch, D. Marckmann, P.I. Trasnea, F. Daldal, H.-G. Koch, Membranes 10 (2020).
View
| Files available
| DOI
A. Andrei, Y. Öztürk, B. Khalfaoui-Hassani, J. Rauch, D. Marckmann, P.I. Trasnea, F. Daldal, H.-G. Koch, Membranes 10 (2020).
2020 | Journal Article | IST-REx-ID: 8581
Cryo-EM structure of the entire mammalian F-type ATP synthase
G. Pinke, L. Zhou, L.A. Sazanov, Nature Structural and Molecular Biology 27 (2020) 1077–1085.
View
| Files available
| DOI
| PubMed | Europe PMC
G. Pinke, L. Zhou, L.A. Sazanov, Nature Structural and Molecular Biology 27 (2020) 1077–1085.
2020 | Journal Article | IST-REx-ID: 8737 |
The coupling mechanism of mammalian respiratory complex I
D. Kampjut, L.A. Sazanov, Science 370 (2020).
View
| Files available
| DOI
| PubMed | Europe PMC
D. Kampjut, L.A. Sazanov, Science 370 (2020).
2020 | Journal Article | IST-REx-ID: 7788 |
NDUFS4 deletion triggers loss of NDUFA12 in Ndufs4−/− mice and Leigh syndrome patients: A stabilizing role for NDUFAF2
M.J.W. Adjobo-Hermans, R. De Haas, P.H.G.M. Willems, A. Wojtala, S.E. Van Emst-De Vries, J.A. Wagenaars, M. Van Den Brand, R.J. Rodenburg, J.A.M. Smeitink, L.G. Nijtmans, L.A. Sazanov, M.R. Wieckowski, W.J.H. Koopman, Biochimica et Biophysica Acta - Bioenergetics 1861 (2020).
View
| Files available
| DOI
| PubMed | Europe PMC
M.J.W. Adjobo-Hermans, R. De Haas, P.H.G.M. Willems, A. Wojtala, S.E. Van Emst-De Vries, J.A. Wagenaars, M. Van Den Brand, R.J. Rodenburg, J.A.M. Smeitink, L.G. Nijtmans, L.A. Sazanov, M.R. Wieckowski, W.J.H. Koopman, Biochimica et Biophysica Acta - Bioenergetics 1861 (2020).
2020 | Journal Article | IST-REx-ID: 8040
Charge transfer and chemo-mechanical coupling in respiratory complex I
C. Gupta, U. Khaniya, C.K. Chan, F. Dehez, M. Shekhar, M.R. Gunner, L.A. Sazanov, C. Chipot, A. Singharoy, Journal of the American Chemical Society 142 (2020) 9220–9230.
View
| DOI
| PubMed | Europe PMC
C. Gupta, U. Khaniya, C.K. Chan, F. Dehez, M. Shekhar, M.R. Gunner, L.A. Sazanov, C. Chipot, A. Singharoy, Journal of the American Chemical Society 142 (2020) 9220–9230.
2019 | Journal Article | IST-REx-ID: 7395 |
Structures of respiratory supercomplex I+III2 reveal functional and conformational crosstalk
J.A. Letts, K. Fiedorczuk, G. Degliesposti, M. Skehel, L.A. Sazanov, Molecular Cell 75 (2019) 1131–1146.e6.
View
| Files available
| DOI
| PubMed | Europe PMC
J.A. Letts, K. Fiedorczuk, G. Degliesposti, M. Skehel, L.A. Sazanov, Molecular Cell 75 (2019) 1131–1146.e6.
2019 | Journal Article | IST-REx-ID: 6352 |
Protective properties of the cultured stem cell proteome studied in an animal model of acetaminophen-induced acute liver failure
A.A. Temnov, K.A. Rogov, A.N. Sklifas, E.V. Klychnikova, M. Hartl, K. Djinovic-Carugo, A. Charnagalov, Molecular Biology Reports (2019).
View
| Files available
| DOI
A.A. Temnov, K.A. Rogov, A.N. Sklifas, E.V. Klychnikova, M. Hartl, K. Djinovic-Carugo, A. Charnagalov, Molecular Biology Reports (2019).
2019 | Journal Article | IST-REx-ID: 6848 |
Structure and mechanism of mitochondrial proton-translocating transhydrogenase
D. Kampjut, L.A. Sazanov, Nature 573 (2019) 291–295.
View
| Files available
| DOI
| PubMed | Europe PMC
D. Kampjut, L.A. Sazanov, Nature 573 (2019) 291–295.
2019 | Journal Article | IST-REx-ID: 6859
Structure and conformational plasticity of the intact Thermus thermophilus V/A-type ATPase
L. Zhou, L.A. Sazanov, Science 365 (2019).
View
| Files available
| DOI
| PubMed | Europe PMC
L. Zhou, L.A. Sazanov, Science 365 (2019).
2019 | Journal Article | IST-REx-ID: 6919 |
Structural basis of sterol recognition by human hedgehog receptor PTCH1
C. Qi, G.D. Minin, I. Vercellino, A. Wutz, V.M. Korkhov, Science Advances 5 (2019).
View
| Files available
| DOI
C. Qi, G.D. Minin, I. Vercellino, A. Wutz, V.M. Korkhov, Science Advances 5 (2019).
2018 | Journal Article | IST-REx-ID: 152 |
Mammalian mitochondrial complex I structure and disease causing mutations
K. Fiedorczuk, L.A. Sazanov, Trends in Cell Biology 28 (2018) 835–867.
View
| Files available
| DOI
K. Fiedorczuk, L.A. Sazanov, Trends in Cell Biology 28 (2018) 835–867.
2017 | Journal Article | IST-REx-ID: 515 |
Clarifying the supercomplex: The higher-order organization of the mitochondrial electron transport chain
J.A. Letts, L.A. Sazanov, Nature Structural and Molecular Biology 24 (2017) 800–808.
View
| Files available
| DOI
J.A. Letts, L.A. Sazanov, Nature Structural and Molecular Biology 24 (2017) 800–808.
2017 | Book Chapter | IST-REx-ID: 444
Structure of respiratory complex I: “Minimal” bacterial and “de luxe” mammalian versions
L.A. Sazanov, in:, M. Wikström (Ed.), Mechanisms of Primary Energy Transduction in Biology , Royal Society of Chemistry, 2017, pp. 25–59.
View
| DOI
L.A. Sazanov, in:, M. Wikström (Ed.), Mechanisms of Primary Energy Transduction in Biology , Royal Society of Chemistry, 2017, pp. 25–59.
2016 | Journal Article | IST-REx-ID: 1276 |
Atomistic determinants of co-enzyme Q reduction at the Qi-site of the cytochrome bc1 complex
P. Postila, K. Kaszuba, P. Kuleta, I. Vattulainen, M. Sarewicz, A. Osyczka, T. Róg, Scientific Reports 6 (2016).
View
| Files available
| DOI
P. Postila, K. Kaszuba, P. Kuleta, I. Vattulainen, M. Sarewicz, A. Osyczka, T. Róg, Scientific Reports 6 (2016).
2016 | Journal Article | IST-REx-ID: 1288
Reversible FMN dissociation from Escherichia coli respiratory complex I
P. Holt, R. Efremov, E. Nakamaru Ogiso, L.A. Sazanov, Biochimica et Biophysica Acta - Bioenergetics 1857 (2016) 1777–1785.
View
| DOI
P. Holt, R. Efremov, E. Nakamaru Ogiso, L.A. Sazanov, Biochimica et Biophysica Acta - Bioenergetics 1857 (2016) 1777–1785.