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Kristina Lukic

Vladyslav Kravchuk

Gergely Pinke

Olga Petrova

Petru Trasnea

Leonid Sazanov

Alexej Charnagalov

Irene Vercellino

Julia Steiner

Domen Kampjut

Javier Gutierrez-Fernandez

Haidai Hu

Karol Kaszuba

Jame Letts

Arianna Cocco

Long Zhou



18 Publications

2020 | Journal Article | IST-REx-ID: 7788   OA
NDUFS4 deletion triggers loss of NDUFA12 in Ndufs4−/− mice and Leigh syndrome patients: A stabilizing role for NDUFAF2
M.J.W. Adjobo-Hermans, R. De Haas, P.H.G.M. Willems, A. Wojtala, S.E. Van Emst-De Vries, J.A. Wagenaars, M. Van Den Brand, R.J. Rodenburg, J.A.M. Smeitink, L.G. Nijtmans, L.A. Sazanov, M.R. Wieckowski, W.J.H. Koopman, Biochimica et Biophysica Acta - Bioenergetics 1861 (2020) 148213.
View | Files available | DOI | PubMed | Europe PMC
 
2019 | Journal Article | IST-REx-ID: 6919   OA
Structural basis of sterol recognition by human hedgehog receptor PTCH1
C. Qi, G.D. Minin, I. Vercellino, A. Wutz, V.M. Korkhov, Science Advances 5 (2019).
View | Files available | DOI
 
2019 | Journal Article | IST-REx-ID: 6352   OA
Protective properties of the cultured stem cell proteome studied in an animal model of acetaminophen-induced acute liver failure
A.A. Temnov, K.A. Rogov, A.N. Sklifas, E.V. Klychnikova, M. Hartl, K. Djinovic-Carugo, A. Charnagalov, Molecular Biology Reports (2019).
View | Files available | DOI
 
2019 | Journal Article | IST-REx-ID: 6859
Structure and conformational plasticity of the intact Thermus thermophilus V/A-type ATPase
L. Zhou, L.A. Sazanov, Science 365 (2019).
View | Files available | DOI | PubMed | Europe PMC
 
2019 | Journal Article | IST-REx-ID: 7395   OA
Structures of respiratory supercomplex I+III2 reveal functional and conformational crosstalk
J.A. Letts, K. Fiedorczuk, G. Degliesposti, M. Skehel, L.A. Sazanov, Molecular Cell 75 (2019) 1131–1146.e6.
View | Files available | DOI | PubMed | Europe PMC
 
2019 | Journal Article | IST-REx-ID: 6848
Structure and mechanism of mitochondrial proton-translocating transhydrogenase
D. Kampjut, L.A. Sazanov, Nature 573 (2019) 291–295.
View | Files available | DOI | PubMed | Europe PMC
 
2018 | Journal Article | IST-REx-ID: 152   OA
Mammalian mitochondrial complex I structure and disease causing mutations
K. Fiedorczuk, L.A. Sazanov, Trends in Cell Biology 28 (2018) 835–867.
View | Files available | DOI
 
2017 | Book Chapter | IST-REx-ID: 444
Structure of respiratory complex I: “Minimal” bacterial and “de luxe” mammalian versions
L.A. Sazanov, in:, M. Wikström (Ed.), Mechanisms of Primary Energy Transduction in Biology , Royal Society of Chemistry, 2017, pp. 25–59.
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2017 | Journal Article | IST-REx-ID: 515   OA
Clarifying the supercomplex: The higher-order organization of the mitochondrial electron transport chain
J.A. Letts, L.A. Sazanov, Nature Structural and Molecular Biology 24 (2017) 800–808.
View | Files available | DOI
 
2016 | Journal Article | IST-REx-ID: 1186   OA
Modular architecture and unique teichoic acid recognition features of choline-binding protein L CbpL contributing to pneumococcal pathogenesis
J. Gutierrez-Fernandez, M. Saleh, M. Alcorlo, A. Gómez Mejóa, D. Pantoja Uceda, M. Treviño, F. Vob, M. Abdullah, S. Galán Bartual, J. Seinen, P. Sánchez Murcia, F. Gago, M. Bruix, S. Hammerschmidt, J. Hermoso, Scientific Reports 6 (2016).
View | Files available | DOI
 
2016 | Journal Article | IST-REx-ID: 1232
The architecture of respiratory supercomplexes
J.A. Letts, K. Fiedorczuk, L.A. Sazanov, Nature 537 (2016) 644–648.
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2016 | Journal Article | IST-REx-ID: 1276   OA
Atomistic determinants of co-enzyme Q reduction at the Qi-site of the cytochrome bc1 complex
P. Postila, K. Kaszuba, P. Kuleta, I. Vattulainen, M. Sarewicz, A. Osyczka, T. Róg, Scientific Reports 6 (2016).
View | Files available | DOI
 
2016 | Journal Article | IST-REx-ID: 1288
Reversible FMN dissociation from Escherichia coli respiratory complex I
P. Holt, R. Efremov, E. Nakamaru Ogiso, L.A. Sazanov, Biochimica et Biophysica Acta - Bioenergetics 1857 (2016) 1777–1785.
View | DOI
 
2016 | Journal Article | IST-REx-ID: 1226   OA
Atomic structure of the entire mammalian mitochondrial complex i
K. Fiedorczuk, J.A. Letts, G. Degliesposti, K. Kaszuba, M. Skehel, L.A. Sazanov, Nature 538 (2016) 406–410.
View | DOI | Download (ext.) | PubMed | Europe PMC
 
2016 | Journal Article | IST-REx-ID: 1209   OA
Purification of ovine respiratory complex i results in a highly active and stable preparation
J.A. Letts, G. Degliesposti, K. Fiedorczuk, M. Skehel, L.A. Sazanov, Journal of Biological Chemistry 291 (2016) 24657–24675.
View | DOI | Download (ext.)
 
2016 | Journal Article | IST-REx-ID: 1521
Structure of bacterial respiratory complex I
J. Berrisford, R. Baradaran, L.A. Sazanov, Biochimica et Biophysica Acta - Bioenergetics 1857 (2016) 892–901.
View | DOI
 
2015 | Journal Article | IST-REx-ID: 1638
A giant molecular proton pump: structure and mechanism of respiratory complex I
L.A. Sazanov, Nature Reviews Molecular Cell Biology 16 (2015) 375–388.
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2015 | Journal Article | IST-REx-ID: 1683
Gaining mass: The structure of respiratory complex I-from bacterial towards mitochondrial versions
J.A. Letts, L.A. Sazanov, Current Opinion in Structural Biology 33 (2015) 135–145.
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