---
_id: '3247'
abstract:
- lang: eng
text: The Brazilian Merganser is a very rare and threatened species that nowadays
inhabits only a few protected areas and their surroundings in the Brazilian territory.
In order to estimate the remaining genetic diversity and population structure
in this species, two mitochondrial genes were sequenced in 39 individuals belonging
to two populations and in one individual collected in Argentina in 1950. We found
a highly significant divergence between two major remaining populations of Mergus
octosetaceus, which suggests a historical population structure in this species.
Furthermore, two deeply divergent lineages were found in a single location, which
could due to current or historical secondary contact. Based on the available genetic
data, we point out future directions which would contribute to design strategies
for conservation and management of this threatened species.
acknowledgement: "The present study received grants from FAPEMIG, CNPq, Petrobras
Ambiental and Fundação O Boticário de Conservação da Natureza, and followed all
ethical guidelines and legal requirements of Brazil for sampling and studying an
endangered species.\r\nWe thank the Specialist Work Group for the Conservation of
Brazilian Merganser for valuable discussions and opinions on this manuscript. We
also thank all the staff from Instituto Terra Brasilis and Funatura (Vivian S. Braz
and Gislaine Disconzi) for collecting the samples at Serra da Canastra and Chapada
dos Veadeiros, respectively; Dario A. Lijtmaerand and Pablo Tubaro for providing
the samples from Argentina, Bradley C. Livezey for sending copies of his papers,
and Geoff M. Hilton and Paulo de Tarso Z. Antas for useful suggestions that greatly
improved this manuscript."
author:
- first_name: Sibelle
full_name: Vilaça, Sibelle
last_name: Vilaça
- first_name: Rodrigo A
full_name: Fernandes Redondo, Rodrigo A
id: 409D5C96-F248-11E8-B48F-1D18A9856A87
last_name: Fernandes Redondo
orcid: 0000-0002-5837-2793
- first_name: Lívia
full_name: Lins, Lívia
last_name: Lins
- first_name: Fabrício
full_name: Santos, Fabrício
last_name: Santos
citation:
ama: Vilaça S, Fernandes Redondo RA, Lins L, Santos F. Remaining genetic diversity
in Brazilian Merganser (Mergus octosetaceus). Conservation Genetics. 2012;13(1):293-298.
doi:10.1007/s10592-011-0262-5
apa: Vilaça, S., Fernandes Redondo, R. A., Lins, L., & Santos, F. (2012). Remaining
genetic diversity in Brazilian Merganser (Mergus octosetaceus). Conservation
Genetics. Springer. https://doi.org/10.1007/s10592-011-0262-5
chicago: Vilaça, Sibelle, Rodrigo A Fernandes Redondo, Lívia Lins, and Fabrício
Santos. “Remaining Genetic Diversity in Brazilian Merganser (Mergus Octosetaceus).”
Conservation Genetics. Springer, 2012. https://doi.org/10.1007/s10592-011-0262-5.
ieee: S. Vilaça, R. A. Fernandes Redondo, L. Lins, and F. Santos, “Remaining genetic
diversity in Brazilian Merganser (Mergus octosetaceus),” Conservation Genetics,
vol. 13, no. 1. Springer, pp. 293–298, 2012.
ista: Vilaça S, Fernandes Redondo RA, Lins L, Santos F. 2012. Remaining genetic
diversity in Brazilian Merganser (Mergus octosetaceus). Conservation Genetics.
13(1), 293–298.
mla: Vilaça, Sibelle, et al. “Remaining Genetic Diversity in Brazilian Merganser
(Mergus Octosetaceus).” Conservation Genetics, vol. 13, no. 1, Springer,
2012, pp. 293–98, doi:10.1007/s10592-011-0262-5.
short: S. Vilaça, R.A. Fernandes Redondo, L. Lins, F. Santos, Conservation Genetics
13 (2012) 293–298.
date_created: 2018-12-11T12:02:15Z
date_published: 2012-02-01T00:00:00Z
date_updated: 2021-01-12T07:42:05Z
day: '01'
department:
- _id: JoBo
doi: 10.1007/s10592-011-0262-5
intvolume: ' 13'
issue: '1'
language:
- iso: eng
month: '02'
oa_version: None
page: 293 - 298
publication: Conservation Genetics
publication_status: published
publisher: Springer
publist_id: '3420'
quality_controlled: '1'
scopus_import: 1
status: public
title: Remaining genetic diversity in Brazilian Merganser (Mergus octosetaceus)
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 13
year: '2012'
...
---
_id: '3289'
abstract:
- lang: eng
text: "Viral manipulation of transduction pathways associated with key cellular
functions such as survival, response to microbial infection, and cytoskeleton
reorganization can provide the supportive milieu for a productive infection. Here,
we demonstrate that vaccinia virus (VACV) infection leads to activation of the
stress-activated protein kinase (SAPK)/extracellular signal-regulated kinase (ERK)
4/7 (MKK4/7)-c-Jun N-terminal protein kinase 1/2 (JNK1/2) pathway; further, the
stimulation of this pathway requires postpenetration, prereplicative events in
the viral replication cycle. Although the formation of intracellular mature virus
(IMV) was not affected in MKK4/7- or JNK1/2-knockout (KO) cells, we did note an
accentuated deregulation of microtubule and actin network organization in infected
JNK1/2-KO cells. This was followed by deregulated viral trafficking to the periphery
and enhanced enveloped particle release. Furthermore, VACV infection induced alterations
in the cell contractility and morphology, and cell migration was reduced in the
JNK-KO cells. In addition, phosphorylation of proteins implicated with early cell
contractility and cell migration, such as microtubule-associated protein 1B and
paxillin, respectively, was not detected in the VACV-infected KO cells. In sum,
our findings uncover a regulatory role played by the MKK4/7-JNK1/2 pathway in
cytoskeleton reorganization during VACV infection.\r\n"
acknowledgement: "This work was supported by grants from Fundação de Amparo a Pesquisa
do Estado de Minas Gerais (FAPEMIG), the Brazilian Federal Agency for Support and
Evaluation of Graduate Education (CAPES), and the National Council for Scientific
and Technological Development (CNPq). A.C.T.C.P., B.S.A.F.B., F.G.G.L., and J.A.P.S.-M.
were recipients of predoctoral fellowships from CNPq. C.A.B., E.G.K., T.S.-P., P.F.P.P.,
and P.C.P.F. are recipients of research fellowships from CNPq. \r\n\r\n\r\nWe are
grateful to Angela S. Lopes, Ilda M. V. Gama, João R. dos Santos, and Andreza A.
Carvalho for their secretarial/technical assistance and to Fernanda Gambogi for
help with immunofluorescence microscopy. We also thank M. C. Sogayar (Department
of Biochemistry, University of São Paulo, São Paulo, Brazil), who kindly provided
us with the A31 cell line, and R. Davis (Howard Hughes Medical Institute, University
of Massachusetts Medical School, Worcester, MA) for the WT and JNK1/2-, MKK4-, MKK7-,
and MKK4/7-KO cells. VACV WR was from C. Jungwirth (Universität Würzburg, Würzburg,
Germany). The recombinant VACV vF13L-GFP and the rabbit polyclonal antibodies against
viral proteins, B5R, D8L, L1R, and A36R, were from B. Moss (NIAID, Bethesda, MD).
The pcDNA3-Myc-JNK2-MKK7 WT plasmid was from Eugen Kerkhoff (Universität Würzburg,
Würzburg, Germany). We also thank Flávio G. da Fonseca (UFMG, Belo Horizonte, MG,
Brazil) and Kathleen A. Boyle (Medical College of Wisconsin, Milwaukee, WI) for
critically reading the manuscript."
author:
- first_name: Anna
full_name: Pereira, Anna
last_name: Pereira
- first_name: Flávia
full_name: Leite, Flávia
id: 36705F98-F248-11E8-B48F-1D18A9856A87
last_name: Leite
- first_name: Bruno
full_name: Brasil, Bruno
last_name: Brasil
- first_name: Jamaria
full_name: Soares Martins, Jamaria
last_name: Soares Martins
- first_name: Alice
full_name: Torres, Alice
last_name: Torres
- first_name: Paulo
full_name: Pimenta, Paulo
last_name: Pimenta
- first_name: Thais
full_name: Souto Padrón, Thais
last_name: Souto Padrón
- first_name: Paula
full_name: Tranktman, Paula
last_name: Tranktman
- first_name: Paulo
full_name: Ferreira, Paulo
last_name: Ferreira
- first_name: Erna
full_name: Kroon, Erna
last_name: Kroon
- first_name: Cláudio
full_name: Bonjardim, Cláudio
last_name: Bonjardim
citation:
ama: Pereira A, Leite F, Brasil B, et al. A vaccinia virus-driven interplay between
the MKK4/7-JNK1/2 pathway and cytoskeleton reorganization. Journal of Virology.
2012;86(1):172-184. doi:10.1128/JVI.05638-11
apa: Pereira, A., Leite, F., Brasil, B., Soares Martins, J., Torres, A., Pimenta,
P., … Bonjardim, C. (2012). A vaccinia virus-driven interplay between the MKK4/7-JNK1/2
pathway and cytoskeleton reorganization. Journal of Virology. ASM. https://doi.org/10.1128/JVI.05638-11
chicago: Pereira, Anna, Flávia Leite, Bruno Brasil, Jamaria Soares Martins, Alice
Torres, Paulo Pimenta, Thais Souto Padrón, et al. “A Vaccinia Virus-Driven Interplay
between the MKK4/7-JNK1/2 Pathway and Cytoskeleton Reorganization.” Journal
of Virology. ASM, 2012. https://doi.org/10.1128/JVI.05638-11.
ieee: A. Pereira et al., “A vaccinia virus-driven interplay between the MKK4/7-JNK1/2
pathway and cytoskeleton reorganization,” Journal of Virology, vol. 86,
no. 1. ASM, pp. 172–184, 2012.
ista: Pereira A, Leite F, Brasil B, Soares Martins J, Torres A, Pimenta P, Souto
Padrón T, Tranktman P, Ferreira P, Kroon E, Bonjardim C. 2012. A vaccinia virus-driven
interplay between the MKK4/7-JNK1/2 pathway and cytoskeleton reorganization. Journal
of Virology. 86(1), 172–184.
mla: Pereira, Anna, et al. “A Vaccinia Virus-Driven Interplay between the MKK4/7-JNK1/2
Pathway and Cytoskeleton Reorganization.” Journal of Virology, vol. 86,
no. 1, ASM, 2012, pp. 172–84, doi:10.1128/JVI.05638-11.
short: A. Pereira, F. Leite, B. Brasil, J. Soares Martins, A. Torres, P. Pimenta,
T. Souto Padrón, P. Tranktman, P. Ferreira, E. Kroon, C. Bonjardim, Journal of
Virology 86 (2012) 172–184.
date_created: 2018-12-11T12:02:29Z
date_published: 2012-01-01T00:00:00Z
date_updated: 2021-01-12T07:42:25Z
day: '01'
department:
- _id: JoBo
doi: 10.1128/JVI.05638-11
external_id:
pmid:
- '22031940'
intvolume: ' 86'
issue: '1'
language:
- iso: eng
main_file_link:
- open_access: '1'
url: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3255887/
month: '01'
oa: 1
oa_version: Submitted Version
page: 172 - 184
pmid: 1
publication: Journal of Virology
publication_status: published
publisher: ASM
publist_id: '3356'
quality_controlled: '1'
scopus_import: 1
status: public
title: A vaccinia virus-driven interplay between the MKK4/7-JNK1/2 pathway and cytoskeleton
reorganization
type: journal_article
user_id: 3E5EF7F0-F248-11E8-B48F-1D18A9856A87
volume: 86
year: '2012'
...
---
_id: '3370'
abstract:
- lang: eng
text: Supertree methods are widely applied and give rise to new conclusions about
phylogenies (e.g., Bininda-Emonds et al. 2007). Although several desiderata for
supertree methods exist (Wilkinson, Thorley, et al. 2004), only few of them have
been studied in greater detail, examples include shape bias (Wilkinson et al.
2005) or pareto properties (Wilkinson et al. 2007). Here I look more closely at
two matrix representation methods, matrix representation with compatibility (MRC)
and matrix representation with parsimony (MRP). Different null models of random
data are studied and the resulting tree shapes are investigated. Thereby I consider
unrooted trees and a bias in tree shape is determined by a tree balance measure.
The measure for unrooted trees is a modification of a tree balance measure for
rooted trees. I observe that depending on the underlying null model of random
data, the methods may resolve conflict in favor of more balanced tree shapes.
The analyses refer only to trees with the same taxon set, also known as the consensus
setting (e.g., Wilkinson et al. 2007), but I will be able to draw conclusions
on how to deal with missing data.
author:
- first_name: Anne
full_name: Kupczok, Anne
id: 2BB22BC2-F248-11E8-B48F-1D18A9856A87
last_name: Kupczok
citation:
ama: Kupczok A. Consequences of different null models on the tree shape bias of
supertree methods. Systematic Biology. 2011;60(2):218-225. doi:10.1093/sysbio/syq086
apa: Kupczok, A. (2011). Consequences of different null models on the tree shape
bias of supertree methods. Systematic Biology. Oxford University Press.
https://doi.org/10.1093/sysbio/syq086
chicago: Kupczok, Anne. “Consequences of Different Null Models on the Tree Shape
Bias of Supertree Methods.” Systematic Biology. Oxford University Press,
2011. https://doi.org/10.1093/sysbio/syq086.
ieee: A. Kupczok, “Consequences of different null models on the tree shape bias
of supertree methods,” Systematic Biology, vol. 60, no. 2. Oxford University
Press, pp. 218–225, 2011.
ista: Kupczok A. 2011. Consequences of different null models on the tree shape bias
of supertree methods. Systematic Biology. 60(2), 218–225.
mla: Kupczok, Anne. “Consequences of Different Null Models on the Tree Shape Bias
of Supertree Methods.” Systematic Biology, vol. 60, no. 2, Oxford University
Press, 2011, pp. 218–25, doi:10.1093/sysbio/syq086.
short: A. Kupczok, Systematic Biology 60 (2011) 218–225.
date_created: 2018-12-11T12:02:57Z
date_published: 2011-03-01T00:00:00Z
date_updated: 2021-01-12T07:43:01Z
day: '01'
department:
- _id: JoBo
doi: 10.1093/sysbio/syq086
intvolume: ' 60'
issue: '2'
language:
- iso: eng
main_file_link:
- open_access: '1'
url: http://eprints.cs.univie.ac.at/3226/
month: '03'
oa: 1
oa_version: Submitted Version
page: 218 - 225
publication: Systematic Biology
publication_status: published
publisher: Oxford University Press
publist_id: '3241'
quality_controlled: '1'
status: public
title: Consequences of different null models on the tree shape bias of supertree methods
type: journal_article
user_id: 4435EBFC-F248-11E8-B48F-1D18A9856A87
volume: 60
year: '2011'
...
---
_id: '3387'
abstract:
- lang: eng
text: 'Background: Supertree methods combine overlapping input trees into a larger
supertree. Here, I consider split-based supertree methods that first extract the
split information of the input trees and subsequently combine this split information
into a phylogeny. Well known split-based supertree methods are matrix representation
with parsimony and matrix representation with compatibility. Combining input trees
on the same taxon set, as in the consensus setting, is a well-studied task and
it is thus desirable to generalize consensus methods to supertree methods. Results:
Here, three variants of majority-rule (MR) supertrees that generalize majority-rule
consensus trees are investigated. I provide simple formulas for computing the
respective score for bifurcating input- and supertrees. These score computations,
together with a heuristic tree search minmizing the scores, were implemented in
the python program PluMiST (Plus- and Minus SuperTrees) available from http://www.cibiv.at/software/
plumist. The different MR methods were tested by simulation and on real data sets.
The search heuristic was successful in combining compatible input trees. When
combining incompatible input trees, especially one variant, MR(-) supertrees,
performed well. Conclusions: The presented framework allows for an efficient score
computation of three majority-rule supertree variants and input trees. I combined
the score computation with a heuristic search over the supertree space. The implementation
was tested by simulation and on real data sets and showed promising results. Especially
the MR(-) variant seems to be a reasonable score for supertree reconstruction.
Generalizing these computations to multifurcating trees is an open problem, which
may be tackled using this framework.'
article_number: '205'
author:
- first_name: Anne
full_name: Kupczok, Anne
id: 2BB22BC2-F248-11E8-B48F-1D18A9856A87
last_name: Kupczok
citation:
ama: Kupczok A. Split based computation of majority rule supertrees. BMC Evolutionary
Biology. 2011;11(205). doi:10.1186/1471-2148-11-205
apa: Kupczok, A. (2011). Split based computation of majority rule supertrees. BMC
Evolutionary Biology. BioMed Central. https://doi.org/10.1186/1471-2148-11-205
chicago: Kupczok, Anne. “Split Based Computation of Majority Rule Supertrees.” BMC
Evolutionary Biology. BioMed Central, 2011. https://doi.org/10.1186/1471-2148-11-205.
ieee: A. Kupczok, “Split based computation of majority rule supertrees,” BMC
Evolutionary Biology, vol. 11, no. 205. BioMed Central, 2011.
ista: Kupczok A. 2011. Split based computation of majority rule supertrees. BMC
Evolutionary Biology. 11(205), 205.
mla: Kupczok, Anne. “Split Based Computation of Majority Rule Supertrees.” BMC
Evolutionary Biology, vol. 11, no. 205, 205, BioMed Central, 2011, doi:10.1186/1471-2148-11-205.
short: A. Kupczok, BMC Evolutionary Biology 11 (2011).
date_created: 2018-12-11T12:03:03Z
date_published: 2011-07-13T00:00:00Z
date_updated: 2021-01-12T07:43:08Z
day: '13'
ddc:
- '576'
department:
- _id: JoBo
doi: 10.1186/1471-2148-11-205
file:
- access_level: open_access
checksum: 68da8d04af1b97b4cbe8606e2f92ddd8
content_type: application/pdf
creator: system
date_created: 2018-12-12T10:14:09Z
date_updated: 2020-07-14T12:46:11Z
file_id: '5058'
file_name: IST-2015-372-v1+1_1471-2148-11-205.pdf
file_size: 465042
relation: main_file
file_date_updated: 2020-07-14T12:46:11Z
has_accepted_license: '1'
intvolume: ' 11'
issue: '205'
language:
- iso: eng
month: '07'
oa: 1
oa_version: Published Version
publication: BMC Evolutionary Biology
publication_status: published
publisher: BioMed Central
publist_id: '3219'
pubrep_id: '372'
quality_controlled: '1'
scopus_import: 1
status: public
title: Split based computation of majority rule supertrees
tmp:
image: /images/cc_by.png
legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
short: CC BY (4.0)
type: journal_article
user_id: 4435EBFC-F248-11E8-B48F-1D18A9856A87
volume: 11
year: '2011'
...
---
_id: '2409'
abstract:
- lang: eng
text: "Background: The availability of many gene alignments with overlapping taxon
sets raises the question of which strategy is the best to infer species phylogenies
from multiple gene information. Methods and programs abound that use the gene
alignment in different ways to reconstruct the species tree. In particular, different
methods combine the original data at different points along the way from the underlying
sequences to the final tree. Accordingly, they are classified into superalignment,
supertree and medium-level approaches. Here, we present a simulation study to
compare different methods from each of these three approaches.\r\n\r\nResults:
We observe that superalignment methods usually outperform the other approaches
over a wide range of parameters including sparse data and gene-specific evolutionary
parameters. In the presence of high incongruency among gene trees, however, other
combination methods show better performance than the superalignment approach.
Surprisingly, some supertree and medium-level methods exhibit, on average, worse
results than a single gene phylogeny with complete taxon information.\r\n\r\nConclusions:
For some methods, using the reconstructed gene tree as an estimation of the species
tree is superior to the combination of incomplete information. Superalignment
usually performs best since it is less susceptible to stochastic error. Supertree
methods can outperform superalignment in the presence of gene-tree conflict."
acknowledgement: Financial support from the Wiener Wissenschafts-, Forschungs- and
Technologiefonds (WWTF) is greatly appreciated. A.v.H. acknowledges support from
the German Research Foundation (DFG, SPP-1174).
article_number: '37'
author:
- first_name: Anne
full_name: Kupczok, Anne
id: 2BB22BC2-F248-11E8-B48F-1D18A9856A87
last_name: Kupczok
- first_name: Heiko
full_name: Schmidt, Heiko
last_name: Schmidt
- first_name: Arndt
full_name: Von Haeseler, Arndt
last_name: Von Haeseler
citation:
ama: Kupczok A, Schmidt H, Von Haeseler A. Accuracy of phylogeny reconstruction
methods combining overlapping gene data sets . Algorithms for Molecular Biology.
2010;5(1). doi:10.1186/1748-7188-5-37
apa: Kupczok, A., Schmidt, H., & Von Haeseler, A. (2010). Accuracy of phylogeny
reconstruction methods combining overlapping gene data sets . Algorithms for
Molecular Biology. BioMed Central. https://doi.org/10.1186/1748-7188-5-37
chicago: Kupczok, Anne, Heiko Schmidt, and Arndt Von Haeseler. “Accuracy of Phylogeny
Reconstruction Methods Combining Overlapping Gene Data Sets .” Algorithms for
Molecular Biology. BioMed Central, 2010. https://doi.org/10.1186/1748-7188-5-37.
ieee: A. Kupczok, H. Schmidt, and A. Von Haeseler, “Accuracy of phylogeny reconstruction
methods combining overlapping gene data sets ,” Algorithms for Molecular Biology,
vol. 5, no. 1. BioMed Central, 2010.
ista: Kupczok A, Schmidt H, Von Haeseler A. 2010. Accuracy of phylogeny reconstruction
methods combining overlapping gene data sets . Algorithms for Molecular Biology.
5(1), 37.
mla: Kupczok, Anne, et al. “Accuracy of Phylogeny Reconstruction Methods Combining
Overlapping Gene Data Sets .” Algorithms for Molecular Biology, vol. 5,
no. 1, 37, BioMed Central, 2010, doi:10.1186/1748-7188-5-37.
short: A. Kupczok, H. Schmidt, A. Von Haeseler, Algorithms for Molecular Biology
5 (2010).
date_created: 2018-12-11T11:57:30Z
date_published: 2010-12-06T00:00:00Z
date_updated: 2021-01-12T06:57:18Z
day: '06'
ddc:
- '576'
department:
- _id: JoBo
doi: 10.1186/1748-7188-5-37
file:
- access_level: open_access
checksum: e2497285388bc4da629bafb46662eb43
content_type: application/pdf
creator: system
date_created: 2018-12-12T10:09:16Z
date_updated: 2020-07-14T12:45:40Z
file_id: '4739'
file_name: IST-2018-939-v1+1_2010_Kupczok_Accuracy_of.pdf
file_size: 723929
relation: main_file
file_date_updated: 2020-07-14T12:45:40Z
has_accepted_license: '1'
intvolume: ' 5'
issue: '1'
language:
- iso: eng
month: '12'
oa: 1
oa_version: Published Version
publication: Algorithms for Molecular Biology
publication_status: published
publisher: BioMed Central
publist_id: '4517'
pubrep_id: '939'
quality_controlled: '1'
scopus_import: 1
status: public
title: 'Accuracy of phylogeny reconstruction methods combining overlapping gene data
sets '
tmp:
image: /images/cc_by.png
legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
short: CC BY (4.0)
type: journal_article
user_id: 3E5EF7F0-F248-11E8-B48F-1D18A9856A87
volume: 5
year: '2010'
...