---
_id: '1417'
abstract:
- lang: eng
text: Plant development mediated by the phytohormone auxin depends on tightly controlled
cellular auxin levels at its target tissue that are largely established by intercellular
and intracellular auxin transport mediated by PIN auxin transporters. Among the
eight members of the Arabidopsis PIN family, PIN6 is the least characterized candidate.
In this study we generated functional, fluorescent protein-tagged PIN6 proteins
and performed comprehensive analysis of their subcellular localization and also
performed a detailed functional characterization of PIN6 and its developmental
roles. The localization study of PIN6 revealed a dual localization at the plasma
membrane (PM) and endoplasmic reticulum (ER). Transport and metabolic profiling
assays in cultured cells and Arabidopsis strongly suggest that PIN6 mediates both
auxin transport across the PM and intracellular auxin homeostasis, including the
regulation of free auxin and auxin conjugates levels. As evidenced by the loss-
and gain-of-function analysis, the complex function of PIN6 in auxin transport
and homeostasis is required for auxin distribution during lateral and adventitious
root organogenesis and for progression of these developmental processes. These
results illustrate a unique position of PIN6 within the family of PIN auxin transporters
and further add complexity to the developmentally crucial process of auxin transport.
acknowledgement: This work was supported by the European Research Council (project
ERC-2011-StG-20101109-PSDP, project CEITEC (CZ.1.05/1.1.00/02.0068) and the Czech
Science Foundation GACR (project no. 13-4063 7S to J.F.)
author:
- first_name: Sibu
full_name: Simon, Sibu
id: 4542EF9A-F248-11E8-B48F-1D18A9856A87
last_name: Simon
orcid: 0000-0002-1998-6741
- first_name: Petr
full_name: Skůpa, Petr
last_name: Skůpa
- first_name: Tom
full_name: Viaene, Tom
last_name: Viaene
- first_name: Marta
full_name: Zwiewka, Marta
last_name: Zwiewka
- first_name: Ricardo
full_name: Tejos, Ricardo
last_name: Tejos
- first_name: Petr
full_name: Klíma, Petr
last_name: Klíma
- first_name: Mária
full_name: Čarná, Mária
last_name: Čarná
- first_name: Jakub
full_name: Rolčík, Jakub
last_name: Rolčík
- first_name: Riet
full_name: De Rycke, Riet
last_name: De Rycke
- first_name: Ignacio
full_name: Moreno, Ignacio
last_name: Moreno
- first_name: Petre
full_name: Dobrev, Petre
last_name: Dobrev
- first_name: Ariel
full_name: Orellana, Ariel
last_name: Orellana
- first_name: Eva
full_name: Zažímalová, Eva
last_name: Zažímalová
- first_name: Jirí
full_name: Friml, Jirí
id: 4159519E-F248-11E8-B48F-1D18A9856A87
last_name: Friml
orcid: 0000-0002-8302-7596
citation:
ama: Simon S, Skůpa P, Viaene T, et al. PIN6 auxin transporter at endoplasmic reticulum
and plasma membrane mediates auxin homeostasis and organogenesis in Arabidopsis.
New Phytologist. 2016;211(1):65-74. doi:10.1111/nph.14019
apa: Simon, S., Skůpa, P., Viaene, T., Zwiewka, M., Tejos, R., Klíma, P., … Friml,
J. (2016). PIN6 auxin transporter at endoplasmic reticulum and plasma membrane
mediates auxin homeostasis and organogenesis in Arabidopsis. New Phytologist.
Wiley-Blackwell. https://doi.org/10.1111/nph.14019
chicago: Simon, Sibu, Petr Skůpa, Tom Viaene, Marta Zwiewka, Ricardo Tejos, Petr
Klíma, Mária Čarná, et al. “PIN6 Auxin Transporter at Endoplasmic Reticulum and
Plasma Membrane Mediates Auxin Homeostasis and Organogenesis in Arabidopsis.”
New Phytologist. Wiley-Blackwell, 2016. https://doi.org/10.1111/nph.14019.
ieee: S. Simon et al., “PIN6 auxin transporter at endoplasmic reticulum and
plasma membrane mediates auxin homeostasis and organogenesis in Arabidopsis,”
New Phytologist, vol. 211, no. 1. Wiley-Blackwell, pp. 65–74, 2016.
ista: Simon S, Skůpa P, Viaene T, Zwiewka M, Tejos R, Klíma P, Čarná M, Rolčík J,
De Rycke R, Moreno I, Dobrev P, Orellana A, Zažímalová E, Friml J. 2016. PIN6
auxin transporter at endoplasmic reticulum and plasma membrane mediates auxin
homeostasis and organogenesis in Arabidopsis. New Phytologist. 211(1), 65–74.
mla: Simon, Sibu, et al. “PIN6 Auxin Transporter at Endoplasmic Reticulum and Plasma
Membrane Mediates Auxin Homeostasis and Organogenesis in Arabidopsis.” New
Phytologist, vol. 211, no. 1, Wiley-Blackwell, 2016, pp. 65–74, doi:10.1111/nph.14019.
short: S. Simon, P. Skůpa, T. Viaene, M. Zwiewka, R. Tejos, P. Klíma, M. Čarná,
J. Rolčík, R. De Rycke, I. Moreno, P. Dobrev, A. Orellana, E. Zažímalová, J. Friml,
New Phytologist 211 (2016) 65–74.
date_created: 2018-12-11T11:51:54Z
date_published: 2016-07-01T00:00:00Z
date_updated: 2021-01-12T06:50:36Z
day: '01'
ddc:
- '581'
department:
- _id: JiFr
doi: 10.1111/nph.14019
file:
- access_level: open_access
checksum: 23522ced3508ffe7a4f247c4230e6493
content_type: application/pdf
creator: system
date_created: 2018-12-12T10:13:32Z
date_updated: 2020-07-14T12:44:53Z
file_id: '5016'
file_name: IST-2018-1004-v1+1_Simon_NewPhytol_2016_proof.pdf
file_size: 3828383
relation: main_file
file_date_updated: 2020-07-14T12:44:53Z
has_accepted_license: '1'
intvolume: ' 211'
issue: '1'
language:
- iso: eng
month: '07'
oa: 1
oa_version: Submitted Version
page: 65 - 74
publication: New Phytologist
publication_status: published
publisher: Wiley-Blackwell
publist_id: '5790'
pubrep_id: '1004'
quality_controlled: '1'
scopus_import: 1
status: public
title: PIN6 auxin transporter at endoplasmic reticulum and plasma membrane mediates
auxin homeostasis and organogenesis in Arabidopsis
type: journal_article
user_id: 3E5EF7F0-F248-11E8-B48F-1D18A9856A87
volume: 211
year: '2016'
...
---
_id: '1482'
abstract:
- lang: eng
text: Plants have the ability to continously generate new organs by maintaining
populations of stem cells throught their lives. The shoot apical meristem (SAM)
provides a stable environment for the maintenance of stem cells. All cells inside
the SAM divide, yet boundaries and patterns are maintained. Experimental evidence
indicates that patterning is independent of cell lineage, thus a dynamic self-regulatory
mechanism is required. A pivotal role in the organization of the SAM is played
by the WUSCHEL gene (WUS). An important question in this regard is that how WUS
expression is positioned in the SAM via a cell-lineage independent signaling mechanism.
In this study we demonstrate via mathematical modeling that a combination of an
inhibitor of the Cytokinin (CK) receptor, Arabidopsis histidine kinase 4 (AHK4)
and two morphogens originating from the top cell layer, can plausibly account
for the cell lineage-independent centering of WUS expression within SAM. Furthermore,
our laser ablation and microsurgical experiments support the hypothesis that patterning
in SAM occurs at the level of CK reception and signaling. The model suggests that
the interplay between CK signaling, WUS/CLV feedback loop and boundary signals
can account for positioning of the WUS expression, and provides directions for
further experimental investigation.
acknowledgement: We thank J. Traas, B. Müller and V. Reddy for providing seed materials
and Y. Deb for advice regarding the laser ablation experiments. We specially thank
Thomas Laux for stimulating discussions and support in the initial phase of this
project.
article_number: e0147830
author:
- first_name: Milad
full_name: Adibi, Milad
last_name: Adibi
- first_name: Saiko
full_name: Yoshida, Saiko
id: 2E46069C-F248-11E8-B48F-1D18A9856A87
last_name: Yoshida
- first_name: Dolf
full_name: Weijers, Dolf
last_name: Weijers
- first_name: Christian
full_name: Fleck, Christian
last_name: Fleck
citation:
ama: Adibi M, Yoshida S, Weijers D, Fleck C. Centering the organizing center in
the Arabidopsis thaliana shoot apical meristem by a combination of cytokinin signaling
and self-organization. PLoS One. 2016;11(2). doi:10.1371/journal.pone.0147830
apa: Adibi, M., Yoshida, S., Weijers, D., & Fleck, C. (2016). Centering the
organizing center in the Arabidopsis thaliana shoot apical meristem by a combination
of cytokinin signaling and self-organization. PLoS One. Public Library
of Science. https://doi.org/10.1371/journal.pone.0147830
chicago: Adibi, Milad, Saiko Yoshida, Dolf Weijers, and Christian Fleck. “Centering
the Organizing Center in the Arabidopsis Thaliana Shoot Apical Meristem by a Combination
of Cytokinin Signaling and Self-Organization.” PLoS One. Public Library
of Science, 2016. https://doi.org/10.1371/journal.pone.0147830.
ieee: M. Adibi, S. Yoshida, D. Weijers, and C. Fleck, “Centering the organizing
center in the Arabidopsis thaliana shoot apical meristem by a combination of cytokinin
signaling and self-organization,” PLoS One, vol. 11, no. 2. Public Library
of Science, 2016.
ista: Adibi M, Yoshida S, Weijers D, Fleck C. 2016. Centering the organizing center
in the Arabidopsis thaliana shoot apical meristem by a combination of cytokinin
signaling and self-organization. PLoS One. 11(2), e0147830.
mla: Adibi, Milad, et al. “Centering the Organizing Center in the Arabidopsis Thaliana
Shoot Apical Meristem by a Combination of Cytokinin Signaling and Self-Organization.”
PLoS One, vol. 11, no. 2, e0147830, Public Library of Science, 2016, doi:10.1371/journal.pone.0147830.
short: M. Adibi, S. Yoshida, D. Weijers, C. Fleck, PLoS One 11 (2016).
date_created: 2018-12-11T11:52:17Z
date_published: 2016-02-01T00:00:00Z
date_updated: 2021-01-12T06:51:03Z
day: '01'
ddc:
- '570'
department:
- _id: JiFr
doi: 10.1371/journal.pone.0147830
file:
- access_level: open_access
checksum: 6066146e527335030f83aa5924ab72a6
content_type: application/pdf
creator: system
date_created: 2018-12-12T10:14:16Z
date_updated: 2020-07-14T12:44:57Z
file_id: '5066'
file_name: IST-2016-521-v1+1_journal.pone.0147830.PDF
file_size: 4297148
relation: main_file
file_date_updated: 2020-07-14T12:44:57Z
has_accepted_license: '1'
intvolume: ' 11'
issue: '2'
language:
- iso: eng
month: '02'
oa: 1
oa_version: Published Version
publication: PLoS One
publication_status: published
publisher: Public Library of Science
publist_id: '5711'
pubrep_id: '521'
quality_controlled: '1'
scopus_import: 1
status: public
title: Centering the organizing center in the Arabidopsis thaliana shoot apical meristem
by a combination of cytokinin signaling and self-organization
tmp:
image: /images/cc_by.png
legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
short: CC BY (4.0)
type: journal_article
user_id: 3E5EF7F0-F248-11E8-B48F-1D18A9856A87
volume: 11
year: '2016'
...
---
_id: '1484'
acknowledgement: We thank Maciek Adamowski for helpful discussions and Qiang Zhu and
Israel Ausin for critical reading of the manuscript. We sincerely apologize to colleagues
whose work we could not include owing to space limitations.
article_type: review
author:
- first_name: Xu
full_name: Chen, Xu
id: 4E5ADCAA-F248-11E8-B48F-1D18A9856A87
last_name: Chen
- first_name: Shuang
full_name: Wu, Shuang
last_name: Wu
- first_name: Zengyu
full_name: Liu, Zengyu
last_name: Liu
- first_name: Jiřĺ
full_name: Friml, Jiřĺ
id: 4159519E-F248-11E8-B48F-1D18A9856A87
last_name: Friml
orcid: 0000-0002-8302-7596
citation:
ama: Chen X, Wu S, Liu Z, Friml J. Environmental and endogenous control of cortical
microtubule orientation. Trends in Cell Biology. 2016;26(6):409-419. doi:10.1016/j.tcb.2016.02.003
apa: Chen, X., Wu, S., Liu, Z., & Friml, J. (2016). Environmental and endogenous
control of cortical microtubule orientation. Trends in Cell Biology. Cell
Press. https://doi.org/10.1016/j.tcb.2016.02.003
chicago: Chen, Xu, Shuang Wu, Zengyu Liu, and Jiří Friml. “Environmental and Endogenous
Control of Cortical Microtubule Orientation.” Trends in Cell Biology. Cell
Press, 2016. https://doi.org/10.1016/j.tcb.2016.02.003.
ieee: X. Chen, S. Wu, Z. Liu, and J. Friml, “Environmental and endogenous control
of cortical microtubule orientation,” Trends in Cell Biology, vol. 26,
no. 6. Cell Press, pp. 409–419, 2016.
ista: Chen X, Wu S, Liu Z, Friml J. 2016. Environmental and endogenous control of
cortical microtubule orientation. Trends in Cell Biology. 26(6), 409–419.
mla: Chen, Xu, et al. “Environmental and Endogenous Control of Cortical Microtubule
Orientation.” Trends in Cell Biology, vol. 26, no. 6, Cell Press, 2016,
pp. 409–19, doi:10.1016/j.tcb.2016.02.003.
short: X. Chen, S. Wu, Z. Liu, J. Friml, Trends in Cell Biology 26 (2016) 409–419.
date_created: 2018-12-11T11:52:17Z
date_published: 2016-06-01T00:00:00Z
date_updated: 2021-01-12T06:51:04Z
day: '01'
ddc:
- '581'
department:
- _id: JiFr
doi: 10.1016/j.tcb.2016.02.003
file:
- access_level: open_access
checksum: b229e5bb4676ec3e27b7b9ea603b3a63
content_type: application/pdf
creator: system
date_created: 2018-12-12T10:15:34Z
date_updated: 2020-07-14T12:44:57Z
file_id: '5155'
file_name: IST-2018-1002-v1+1_Chen_TICB_2016_proofs.pdf
file_size: 2329117
relation: main_file
file_date_updated: 2020-07-14T12:44:57Z
has_accepted_license: '1'
intvolume: ' 26'
issue: '6'
language:
- iso: eng
month: '06'
oa: 1
oa_version: Submitted Version
page: 409 - 419
publication: Trends in Cell Biology
publication_status: published
publisher: Cell Press
publist_id: '5704'
pubrep_id: '1002'
quality_controlled: '1'
scopus_import: 1
status: public
title: Environmental and endogenous control of cortical microtubule orientation
type: journal_article
user_id: 3E5EF7F0-F248-11E8-B48F-1D18A9856A87
volume: 26
year: '2016'
...
---
_id: '1641'
abstract:
- lang: eng
text: The plant hormone auxin (indole-3-acetic acid) is a major regulator of plant
growth and development including embryo and root patterning, lateral organ formation
and growth responses to environmental stimuli. Auxin is directionally transported
from cell to cell by the action of specific auxin influx [AUXIN-RESISTANT1 (AUX1)]
and efflux [PIN-FORMED (PIN)] transport regulators, whose polar, subcellular localizations
are aligned with the direction of the auxin flow. Auxin itself regulates its own
transport by modulation of the expression and subcellular localization of the
auxin transporters. Increased auxin levels promote the transcription of PIN2 and
AUX1 genes as well as stabilize PIN proteins at the plasma membrane, whereas prolonged
auxin exposure increases the turnover of PIN proteins and their degradation in
the vacuole. In this study, we applied a forward genetic approach, to identify
molecular components playing a role in the auxin-mediated degradation. We generated
EMS-mutagenized Arabidopsis PIN2::PIN2:GFP, AUX1::AUX1:YFP eir1aux1 populations
and designed a screen for mutants with persistently strong fluorescent signals
of the tagged PIN2 and AUX1 after prolonged treatment with the synthetic auxin
2,4-dichlorophenoxyacetic acid (2,4-D). This approach yielded novel auxin degradation
mutants defective in trafficking and degradation of PIN2 and AUX1 proteins and
established a role for auxin-mediated degradation in plant development.
acknowledgement: 'European Social Fund (CZ.1.07/2.3.00/20.0043) and the Czech Science
Foundation GAČR (GA13-40637S) to JF. '
author:
- first_name: Radka
full_name: Zemová, Radka
last_name: Zemová
- first_name: Marta
full_name: Zwiewka, Marta
last_name: Zwiewka
- first_name: Agnieszka
full_name: Bielach, Agnieszka
last_name: Bielach
- first_name: Hélène
full_name: Robert, Hélène
last_name: Robert
- first_name: Jirí
full_name: Friml, Jirí
id: 4159519E-F248-11E8-B48F-1D18A9856A87
last_name: Friml
orcid: 0000-0002-8302-7596
citation:
ama: Zemová R, Zwiewka M, Bielach A, Robert H, Friml J. A forward genetic screen
for new regulators of auxin mediated degradation of auxin transport proteins in
Arabidopsis thaliana. Journal of Plant Growth Regulation. 2016;35(2):465-476.
doi:10.1007/s00344-015-9553-2
apa: Zemová, R., Zwiewka, M., Bielach, A., Robert, H., & Friml, J. (2016). A
forward genetic screen for new regulators of auxin mediated degradation of auxin
transport proteins in Arabidopsis thaliana. Journal of Plant Growth Regulation.
Springer. https://doi.org/10.1007/s00344-015-9553-2
chicago: Zemová, Radka, Marta Zwiewka, Agnieszka Bielach, Hélène Robert, and Jiří
Friml. “A Forward Genetic Screen for New Regulators of Auxin Mediated Degradation
of Auxin Transport Proteins in Arabidopsis Thaliana.” Journal of Plant Growth
Regulation. Springer, 2016. https://doi.org/10.1007/s00344-015-9553-2.
ieee: R. Zemová, M. Zwiewka, A. Bielach, H. Robert, and J. Friml, “A forward genetic
screen for new regulators of auxin mediated degradation of auxin transport proteins
in Arabidopsis thaliana,” Journal of Plant Growth Regulation, vol. 35,
no. 2. Springer, pp. 465–476, 2016.
ista: Zemová R, Zwiewka M, Bielach A, Robert H, Friml J. 2016. A forward genetic
screen for new regulators of auxin mediated degradation of auxin transport proteins
in Arabidopsis thaliana. Journal of Plant Growth Regulation. 35(2), 465–476.
mla: Zemová, Radka, et al. “A Forward Genetic Screen for New Regulators of Auxin
Mediated Degradation of Auxin Transport Proteins in Arabidopsis Thaliana.” Journal
of Plant Growth Regulation, vol. 35, no. 2, Springer, 2016, pp. 465–76, doi:10.1007/s00344-015-9553-2.
short: R. Zemová, M. Zwiewka, A. Bielach, H. Robert, J. Friml, Journal of Plant
Growth Regulation 35 (2016) 465–476.
date_created: 2018-12-11T11:53:12Z
date_published: 2016-06-01T00:00:00Z
date_updated: 2021-01-12T06:52:11Z
day: '01'
ddc:
- '581'
department:
- _id: JiFr
doi: 10.1007/s00344-015-9553-2
file:
- access_level: open_access
checksum: 0dc6a300cde6536ceedd2bcdd2060efb
content_type: application/pdf
creator: system
date_created: 2018-12-12T10:08:34Z
date_updated: 2020-07-14T12:45:08Z
file_id: '4695'
file_name: IST-2018-1001-v1+1_Zemova_JPlantGrowthRegul_2016_proofs.pdf
file_size: 5637591
relation: main_file
file_date_updated: 2020-07-14T12:45:08Z
has_accepted_license: '1'
intvolume: ' 35'
issue: '2'
language:
- iso: eng
month: '06'
oa: 1
oa_version: Preprint
page: 465 - 476
publication: Journal of Plant Growth Regulation
publication_status: published
publisher: Springer
publist_id: '5512'
pubrep_id: '1001'
quality_controlled: '1'
scopus_import: 1
status: public
title: A forward genetic screen for new regulators of auxin mediated degradation of
auxin transport proteins in Arabidopsis thaliana
type: journal_article
user_id: 3E5EF7F0-F248-11E8-B48F-1D18A9856A87
volume: 35
year: '2016'
...
---
_id: '1346'
abstract:
- lang: eng
text: ATP production requires the establishment of an electrochemical proton gradient
across the inner mitochondrial membrane. Mitochondrial uncouplers dissipate this
proton gradient and disrupt numerous cellular processes, including vesicular trafficking,
mainly through energy depletion. Here we show that Endosidin9 (ES9), a novel mitochondrial
uncoupler, is a potent inhibitor of clathrin-mediated endocytosis (CME) in different
systems and that ES9 induces inhibition of CME not because of its effect on cellular
ATP, but rather due to its protonophore activity that leads to cytoplasm acidification.
We show that the known tyrosine kinase inhibitor tyrphostinA23, which is routinely
used to block CME, displays similar properties, thus questioning its use as a
specific inhibitor of cargo recognition by the AP-2 adaptor complex via tyrosine
motif-based endocytosis signals. Furthermore, we show that cytoplasm acidification
dramatically affects the dynamics and recruitment of clathrin and associated adaptors,
and leads to reduction of phosphatidylinositol 4,5-biphosphate from the plasma
membrane.
acknowledgement: "We thank Yvon Jaillais, Ikuko Hara-Nishimura, Akihiko Nakano, Takashi
Ueda and Jinxing Lin for providing materials, Natasha Raikhel, Glenn Hicks, Steffen
Vanneste, and Ricardo Tejos for useful suggestions, Patrick Callaerts for providing
S2 Drosophila cell cultures, Michael Sixt for providing HeLa cells, Annick Bleys
for literature searches, VIB Bio Imaging Core for help with imaging conditions and
Martine De Cock for help in preparing the article. This work was supported by the
Agency for Innovation by Science\r\nand Technology for a pre-doctoral fellowship
to W.D.; the Research fund KU Leuven\r\n(GOA), a Methusalem grant of the Flemish
government and VIB to S.K., J.K. and P.V.;\r\nby the Netherlands Organisation for
Scientific Research (NWO) for ALW grants\r\n846.11.002 (C.T.) and 867.15.020 (T.M.);
the European Research Council (project\r\nERC-2011-StG-20101109 PSDP) (to J.F.);
a European Research Council (ERC) Starting\r\nGrant (grant 260678) (to P.V.), the
Research Foundation-Flanders (grants G.0747.09,\r\nG094011 and G095511) (to P.V.),
the Hercules Foundation, an Interuniversity Attraction\r\nPoles Poles Program, initiated
by the Belgian State, Science Policy Office (to P.V.),\r\nthe Swedish VetenskapsRådet
grant to O.K., the Ghent University ‘Bijzonder\r\nOnderzoek Fonds’ (BOF) for a predoctoral
fellowship to F.A.O.-M., the Research\r\nFoundation-Flanders (FWO) to K.M. and E.R."
article_number: '11710'
author:
- first_name: Wim
full_name: Dejonghe, Wim
last_name: Dejonghe
- first_name: Sabine
full_name: Kuenen, Sabine
last_name: Kuenen
- first_name: Evelien
full_name: Mylle, Evelien
last_name: Mylle
- first_name: Mina K
full_name: Vasileva, Mina K
id: 3407EB18-F248-11E8-B48F-1D18A9856A87
last_name: Vasileva
- first_name: Olivier
full_name: Keech, Olivier
last_name: Keech
- first_name: Corrado
full_name: Viotti, Corrado
last_name: Viotti
- first_name: Jef
full_name: Swerts, Jef
last_name: Swerts
- first_name: Matyas
full_name: Fendrych, Matyas
id: 43905548-F248-11E8-B48F-1D18A9856A87
last_name: Fendrych
orcid: 0000-0002-9767-8699
- first_name: Fausto
full_name: Ortiz Morea, Fausto
last_name: Ortiz Morea
- first_name: Kiril
full_name: Mishev, Kiril
last_name: Mishev
- first_name: Simon
full_name: Delang, Simon
last_name: Delang
- first_name: Stefan
full_name: Scholl, Stefan
last_name: Scholl
- first_name: Xavier
full_name: Zarza, Xavier
last_name: Zarza
- first_name: Mareike
full_name: Heilmann, Mareike
last_name: Heilmann
- first_name: Jiorgos
full_name: Kourelis, Jiorgos
last_name: Kourelis
- first_name: Jaroslaw
full_name: Kasprowicz, Jaroslaw
last_name: Kasprowicz
- first_name: Le
full_name: Nguyen, Le
last_name: Nguyen
- first_name: Andrzej
full_name: Drozdzecki, Andrzej
last_name: Drozdzecki
- first_name: Isabelle
full_name: Van Houtte, Isabelle
last_name: Van Houtte
- first_name: Anna
full_name: Szatmári, Anna
last_name: Szatmári
- first_name: Mateusz
full_name: Majda, Mateusz
last_name: Majda
- first_name: Gary
full_name: Baisa, Gary
last_name: Baisa
- first_name: Sebastian
full_name: Bednarek, Sebastian
last_name: Bednarek
- first_name: Stéphanie
full_name: Robert, Stéphanie
last_name: Robert
- first_name: Dominique
full_name: Audenaert, Dominique
last_name: Audenaert
- first_name: Christa
full_name: Testerink, Christa
last_name: Testerink
- first_name: Teun
full_name: Munnik, Teun
last_name: Munnik
- first_name: Daniël
full_name: Van Damme, Daniël
last_name: Van Damme
- first_name: Ingo
full_name: Heilmann, Ingo
last_name: Heilmann
- first_name: Karin
full_name: Schumacher, Karin
last_name: Schumacher
- first_name: Johan
full_name: Winne, Johan
last_name: Winne
- first_name: Jirí
full_name: Friml, Jirí
id: 4159519E-F248-11E8-B48F-1D18A9856A87
last_name: Friml
orcid: 0000-0002-8302-7596
- first_name: Patrik
full_name: Verstreken, Patrik
last_name: Verstreken
- first_name: Eugenia
full_name: Russinova, Eugenia
last_name: Russinova
citation:
ama: Dejonghe W, Kuenen S, Mylle E, et al. Mitochondrial uncouplers inhibit clathrin-mediated
endocytosis largely through cytoplasmic acidification. Nature Communications.
2016;7. doi:10.1038/ncomms11710
apa: Dejonghe, W., Kuenen, S., Mylle, E., Vasileva, M. K., Keech, O., Viotti, C.,
… Russinova, E. (2016). Mitochondrial uncouplers inhibit clathrin-mediated endocytosis
largely through cytoplasmic acidification. Nature Communications. Nature
Publishing Group. https://doi.org/10.1038/ncomms11710
chicago: Dejonghe, Wim, Sabine Kuenen, Evelien Mylle, Mina K Vasileva, Olivier Keech,
Corrado Viotti, Jef Swerts, et al. “Mitochondrial Uncouplers Inhibit Clathrin-Mediated
Endocytosis Largely through Cytoplasmic Acidification.” Nature Communications.
Nature Publishing Group, 2016. https://doi.org/10.1038/ncomms11710.
ieee: W. Dejonghe et al., “Mitochondrial uncouplers inhibit clathrin-mediated
endocytosis largely through cytoplasmic acidification,” Nature Communications,
vol. 7. Nature Publishing Group, 2016.
ista: Dejonghe W, Kuenen S, Mylle E, Vasileva MK, Keech O, Viotti C, Swerts J, Fendrych
M, Ortiz Morea F, Mishev K, Delang S, Scholl S, Zarza X, Heilmann M, Kourelis
J, Kasprowicz J, Nguyen L, Drozdzecki A, Van Houtte I, Szatmári A, Majda M, Baisa
G, Bednarek S, Robert S, Audenaert D, Testerink C, Munnik T, Van Damme D, Heilmann
I, Schumacher K, Winne J, Friml J, Verstreken P, Russinova E. 2016. Mitochondrial
uncouplers inhibit clathrin-mediated endocytosis largely through cytoplasmic acidification.
Nature Communications. 7, 11710.
mla: Dejonghe, Wim, et al. “Mitochondrial Uncouplers Inhibit Clathrin-Mediated Endocytosis
Largely through Cytoplasmic Acidification.” Nature Communications, vol.
7, 11710, Nature Publishing Group, 2016, doi:10.1038/ncomms11710.
short: W. Dejonghe, S. Kuenen, E. Mylle, M.K. Vasileva, O. Keech, C. Viotti, J.
Swerts, M. Fendrych, F. Ortiz Morea, K. Mishev, S. Delang, S. Scholl, X. Zarza,
M. Heilmann, J. Kourelis, J. Kasprowicz, L. Nguyen, A. Drozdzecki, I. Van Houtte,
A. Szatmári, M. Majda, G. Baisa, S. Bednarek, S. Robert, D. Audenaert, C. Testerink,
T. Munnik, D. Van Damme, I. Heilmann, K. Schumacher, J. Winne, J. Friml, P. Verstreken,
E. Russinova, Nature Communications 7 (2016).
date_created: 2018-12-11T11:51:30Z
date_published: 2016-06-08T00:00:00Z
date_updated: 2023-09-07T12:54:35Z
day: '08'
ddc:
- '570'
department:
- _id: JiFr
doi: 10.1038/ncomms11710
ec_funded: 1
file:
- access_level: open_access
checksum: e8dc81b3e44db5a7718d7f1501ce1aa7
content_type: application/pdf
creator: system
date_created: 2018-12-12T10:18:47Z
date_updated: 2020-07-14T12:44:45Z
file_id: '5369'
file_name: IST-2016-653-v1+1_ncomms11710_1_.pdf
file_size: 3532505
relation: main_file
file_date_updated: 2020-07-14T12:44:45Z
has_accepted_license: '1'
intvolume: ' 7'
language:
- iso: eng
month: '06'
oa: 1
oa_version: Published Version
project:
- _id: 25716A02-B435-11E9-9278-68D0E5697425
call_identifier: FP7
grant_number: '282300'
name: Polarity and subcellular dynamics in plants
publication: Nature Communications
publication_status: published
publisher: Nature Publishing Group
publist_id: '5906'
pubrep_id: '653'
quality_controlled: '1'
related_material:
record:
- id: '7172'
relation: dissertation_contains
status: public
scopus_import: 1
status: public
title: Mitochondrial uncouplers inhibit clathrin-mediated endocytosis largely through
cytoplasmic acidification
tmp:
image: /images/cc_by.png
legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
short: CC BY (4.0)
type: journal_article
user_id: 3E5EF7F0-F248-11E8-B48F-1D18A9856A87
volume: 7
year: '2016'
...
---
_id: '510'
abstract:
- lang: eng
text: 'The CLE (CLAVATA3/Embryo Surrounding Region-related) peptides are small secreted
signaling peptides that are primarily involved in the regulation of stem cell
homeostasis in different plant meristems. Particularly, the characterization of
the CLE41-PXY/TDR signaling pathway has greatly advanced our understanding on
the potential roles of CLE peptides in vascular development and wood formation.
Nevertheless, our knowledge on this gene family in a tree species is limited.
In a recent study, we reported on a systematically investigation of the CLE gene
family in Populus trichocarpa . The potential roles of PtCLE genes were studied
by comparative analysis and transcriptional pro fi ling. Among fi fty PtCLE members,
many PtCLE proteins share identical CLE motifs or contain the same CLE motif as
that of AtCLEs, while PtCLE genes exhibited either comparable or distinct expression
patterns comparing to their Arabidopsis counterparts. These fi ndings indicate
the existence of both functional conservation and functional divergence between
PtCLEs and their AtCLE orthologues. Our results provide valuable resources for
future functional investigations of these critical signaling molecules in woody
plants. '
acknowledgement: 'We are grateful to Dr. Long (Laboratoire de Reproduction et Developpement
des Plantes,CNRS,INRA,ENSLyon,UCBL,Universite de Lyon,France)for critical reading
of the article. Work in our group is supported by the National Natural Science Foundation
of China (31271575; 31200902), the Fundamental Research Funds for the Central Univ
ersities (GK201103005), the Specialized Research Fund for the Doctoral Program of
Higher Education from the Ministry of Education of China (20120202120009), the Scientific
Research Foundation for the Returned Overseas Chinese Scholars, State Education
Ministry, and the Natural Science Basic Research Plan in Shaanxi Province of China
(2014JM3064). '
article_number: e1191734
article_processing_charge: No
author:
- first_name: Zhijun
full_name: Liu, Zhijun
last_name: Liu
- first_name: 'Nan'
full_name: Yang, Nan
last_name: Yang
- first_name: Yanting
full_name: Lv, Yanting
last_name: Lv
- first_name: Lixia
full_name: Pan, Lixia
last_name: Pan
- first_name: Shuo
full_name: Lv, Shuo
last_name: Lv
- first_name: Huibin
full_name: Han, Huibin
id: 31435098-F248-11E8-B48F-1D18A9856A87
last_name: Han
- first_name: Guodong
full_name: Wang, Guodong
last_name: Wang
citation:
ama: Liu Z, Yang N, Lv Y, et al. The CLE gene family in Populus trichocarpa. Plant
Signaling & Behavior. 2016;11(6). doi:10.1080/15592324.2016.1191734
apa: Liu, Z., Yang, N., Lv, Y., Pan, L., Lv, S., Han, H., & Wang, G. (2016).
The CLE gene family in Populus trichocarpa. Plant Signaling & Behavior.
Taylor & Francis. https://doi.org/10.1080/15592324.2016.1191734
chicago: Liu, Zhijun, Nan Yang, Yanting Lv, Lixia Pan, Shuo Lv, Huibin Han, and
Guodong Wang. “The CLE Gene Family in Populus Trichocarpa.” Plant Signaling
& Behavior. Taylor & Francis, 2016. https://doi.org/10.1080/15592324.2016.1191734.
ieee: Z. Liu et al., “The CLE gene family in Populus trichocarpa,” Plant
Signaling & Behavior, vol. 11, no. 6. Taylor & Francis, 2016.
ista: Liu Z, Yang N, Lv Y, Pan L, Lv S, Han H, Wang G. 2016. The CLE gene family
in Populus trichocarpa. Plant Signaling & Behavior. 11(6), e1191734.
mla: Liu, Zhijun, et al. “The CLE Gene Family in Populus Trichocarpa.” Plant
Signaling & Behavior, vol. 11, no. 6, e1191734, Taylor & Francis,
2016, doi:10.1080/15592324.2016.1191734.
short: Z. Liu, N. Yang, Y. Lv, L. Pan, S. Lv, H. Han, G. Wang, Plant Signaling &
Behavior 11 (2016).
date_created: 2018-12-11T11:46:53Z
date_published: 2016-06-02T00:00:00Z
date_updated: 2023-10-17T11:13:40Z
day: '02'
department:
- _id: JiFr
doi: 10.1080/15592324.2016.1191734
intvolume: ' 11'
issue: '6'
language:
- iso: eng
main_file_link:
- open_access: '1'
url: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4973754/
month: '06'
oa: 1
oa_version: Submitted Version
publication: Plant Signaling & Behavior
publication_status: published
publisher: Taylor & Francis
publist_id: '7308'
quality_controlled: '1'
scopus_import: '1'
status: public
title: The CLE gene family in Populus trichocarpa
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 11
year: '2016'
...
---
_id: '1274'
abstract:
- lang: eng
text: Synchronized tissue polarization during regeneration or de novo vascular tissue
formation is a plant-specific example of intercellular communication and coordinated
development. According to the canalization hypothesis, the plant hormone auxin
serves as polarizing signal that mediates directional channel formation underlying
the spatio-temporal vasculature patterning. A necessary part of canalization is
a positive feedback between auxin signaling and polarity of the intercellular
auxin flow. The cellular and molecular mechanisms of this process are still poorly
understood, not the least, because of a lack of a suitable model system. We show
that the main genetic model plant, Arabidopsis (Arabidopsis thaliana) can be used
to study the canalization during vascular cambium regeneration and new vasculature
formation. We monitored localized auxin responses, directional auxin-transport
channels formation, and establishment of new vascular cambium polarity during
regenerative processes after stem wounding. The increased auxin response above
and around the wound preceded the formation of PIN1 auxin transporter-marked channels
from the primarily homogenous tissue and the transient, gradual changes in PIN1
localization preceded the polarity of newly formed vascular tissue. Thus, Arabidopsis
is a useful model for studies of coordinated tissue polarization and vasculature
formation after wounding allowing for genetic and mechanistic dissection of the
canalization hypothesis.
acknowledgement: We wish to thank Prof. Ewa U. Kurczyńska for initiation of this work
and valuable advices. We thank Martine De Cock for help in preparing the manuscript.
This work was supported by the European Research Council (project ERC-2011-StG-20101109-PSDP),
the European Social Fund (CZ.1.07/2.3.00/20.0043), and the Czech Science Foundation
GAČR (GA13-40637 S) to J.F., (GA 13-39982S) to E.B. and E.M. and in part by the
European Regional Development Fund (project “CEITEC, Central European Institute
of Technology”, CZ.1.05/1.1.00/02.0068).
article_number: '33754'
article_processing_charge: No
author:
- first_name: Ewa
full_name: Mazur, Ewa
last_name: Mazur
- first_name: Eva
full_name: Benková, Eva
id: 38F4F166-F248-11E8-B48F-1D18A9856A87
last_name: Benková
orcid: 0000-0002-8510-9739
- first_name: Jirí
full_name: Friml, Jirí
id: 4159519E-F248-11E8-B48F-1D18A9856A87
last_name: Friml
orcid: 0000-0002-8302-7596
citation:
ama: Mazur E, Benková E, Friml J. Vascular cambium regeneration and vessel formation
in wounded inflorescence stems of Arabidopsis. Scientific Reports. 2016;6.
doi:10.1038/srep33754
apa: Mazur, E., Benková, E., & Friml, J. (2016). Vascular cambium regeneration
and vessel formation in wounded inflorescence stems of Arabidopsis. Scientific
Reports. Nature Publishing Group. https://doi.org/10.1038/srep33754
chicago: Mazur, Ewa, Eva Benková, and Jiří Friml. “Vascular Cambium Regeneration
and Vessel Formation in Wounded Inflorescence Stems of Arabidopsis.” Scientific
Reports. Nature Publishing Group, 2016. https://doi.org/10.1038/srep33754.
ieee: E. Mazur, E. Benková, and J. Friml, “Vascular cambium regeneration and vessel
formation in wounded inflorescence stems of Arabidopsis,” Scientific Reports,
vol. 6. Nature Publishing Group, 2016.
ista: Mazur E, Benková E, Friml J. 2016. Vascular cambium regeneration and vessel
formation in wounded inflorescence stems of Arabidopsis. Scientific Reports. 6,
33754.
mla: Mazur, Ewa, et al. “Vascular Cambium Regeneration and Vessel Formation in Wounded
Inflorescence Stems of Arabidopsis.” Scientific Reports, vol. 6, 33754,
Nature Publishing Group, 2016, doi:10.1038/srep33754.
short: E. Mazur, E. Benková, J. Friml, Scientific Reports 6 (2016).
date_created: 2018-12-11T11:51:05Z
date_published: 2016-09-21T00:00:00Z
date_updated: 2024-02-12T12:03:42Z
day: '21'
ddc:
- '581'
department:
- _id: EvBe
- _id: JiFr
doi: 10.1038/srep33754
external_id:
pmid:
- '27649687'
file:
- access_level: open_access
checksum: ee371fbc9124ad93157a95829264e4fe
content_type: application/pdf
creator: system
date_created: 2018-12-12T10:13:25Z
date_updated: 2020-07-14T12:44:42Z
file_id: '5008'
file_name: IST-2016-692-v1+1_srep33754.pdf
file_size: 2895147
relation: main_file
file_date_updated: 2020-07-14T12:44:42Z
has_accepted_license: '1'
intvolume: ' 6'
language:
- iso: eng
month: '09'
oa: 1
oa_version: Published Version
pmid: 1
publication: Scientific Reports
publication_status: published
publisher: Nature Publishing Group
publist_id: '6042'
pubrep_id: '692'
quality_controlled: '1'
related_material:
record:
- id: '545'
relation: later_version
status: public
scopus_import: '1'
status: public
title: Vascular cambium regeneration and vessel formation in wounded inflorescence
stems of Arabidopsis
tmp:
image: /images/cc_by.png
legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
short: CC BY (4.0)
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 6
year: '2016'
...
---
_id: '1383'
abstract:
- lang: eng
text: In plants, vacuolar H+-ATPase (V-ATPase) activity acidifies both the trans-Golgi
network/early endosome (TGN/EE) and the vacuole. This dual V-ATPase function has
impeded our understanding of how the pH homeostasis within the plant TGN/EE controls
exo- and endocytosis. Here, we show that the weak V-ATPase mutant deetiolated3
(det3) displayed a pH increase in the TGN/EE, but not in the vacuole, strongly
impairing secretion and recycling of the brassinosteroid receptor and the cellulose
synthase complexes to the plasma membrane, in contrast to mutants lacking tonoplast-localized
V-ATPase activity only. The brassinosteroid insensitivity and the cellulose deficiency
defects in det3 were tightly correlated with reduced Golgi and TGN/EE motility.
Thus, our results provide strong evidence that acidification of the TGN/EE, but
not of the vacuole, is indispensable for functional secretion and recycling in
plants.
article_number: '15094'
article_processing_charge: No
article_type: original
author:
- first_name: Luo
full_name: Yu, Luo
last_name: Yu
- first_name: Stefan
full_name: Scholl, Stefan
last_name: Scholl
- first_name: Anett
full_name: Doering, Anett
last_name: Doering
- first_name: Zhang
full_name: Yi, Zhang
last_name: Yi
- first_name: Niloufer
full_name: Irani, Niloufer
last_name: Irani
- first_name: Simone
full_name: Di Rubbo, Simone
last_name: Di Rubbo
- first_name: Lutz
full_name: Neumetzler, Lutz
last_name: Neumetzler
- first_name: Praveen
full_name: Krishnamoorthy, Praveen
last_name: Krishnamoorthy
- first_name: Isabelle
full_name: Van Houtte, Isabelle
last_name: Van Houtte
- first_name: Evelien
full_name: Mylle, Evelien
last_name: Mylle
- first_name: Volker
full_name: Bischoff, Volker
last_name: Bischoff
- first_name: Samantha
full_name: Vernhettes, Samantha
last_name: Vernhettes
- first_name: Johan
full_name: Winne, Johan
last_name: Winne
- first_name: Jirí
full_name: Friml, Jirí
id: 4159519E-F248-11E8-B48F-1D18A9856A87
last_name: Friml
orcid: 0000-0002-8302-7596
- first_name: York
full_name: Stierhof, York
last_name: Stierhof
- first_name: Karin
full_name: Schumacher, Karin
last_name: Schumacher
- first_name: Staffan
full_name: Persson, Staffan
last_name: Persson
- first_name: Eugenia
full_name: Russinova, Eugenia
last_name: Russinova
citation:
ama: Yu L, Scholl S, Doering A, et al. V-ATPase activity in the TGN/EE is required
for exocytosis and recycling in Arabidopsis. Nature Plants. 2015;1(7).
doi:10.1038/nplants.2015.94
apa: Yu, L., Scholl, S., Doering, A., Yi, Z., Irani, N., Di Rubbo, S., … Russinova,
E. (2015). V-ATPase activity in the TGN/EE is required for exocytosis and recycling
in Arabidopsis. Nature Plants. Nature Publishing Group. https://doi.org/10.1038/nplants.2015.94
chicago: Yu, Luo, Stefan Scholl, Anett Doering, Zhang Yi, Niloufer Irani, Simone
Di Rubbo, Lutz Neumetzler, et al. “V-ATPase Activity in the TGN/EE Is Required
for Exocytosis and Recycling in Arabidopsis.” Nature Plants. Nature Publishing
Group, 2015. https://doi.org/10.1038/nplants.2015.94.
ieee: L. Yu et al., “V-ATPase activity in the TGN/EE is required for exocytosis
and recycling in Arabidopsis,” Nature Plants, vol. 1, no. 7. Nature Publishing
Group, 2015.
ista: Yu L, Scholl S, Doering A, Yi Z, Irani N, Di Rubbo S, Neumetzler L, Krishnamoorthy
P, Van Houtte I, Mylle E, Bischoff V, Vernhettes S, Winne J, Friml J, Stierhof
Y, Schumacher K, Persson S, Russinova E. 2015. V-ATPase activity in the TGN/EE
is required for exocytosis and recycling in Arabidopsis. Nature Plants. 1(7),
15094.
mla: Yu, Luo, et al. “V-ATPase Activity in the TGN/EE Is Required for Exocytosis
and Recycling in Arabidopsis.” Nature Plants, vol. 1, no. 7, 15094, Nature
Publishing Group, 2015, doi:10.1038/nplants.2015.94.
short: L. Yu, S. Scholl, A. Doering, Z. Yi, N. Irani, S. Di Rubbo, L. Neumetzler,
P. Krishnamoorthy, I. Van Houtte, E. Mylle, V. Bischoff, S. Vernhettes, J. Winne,
J. Friml, Y. Stierhof, K. Schumacher, S. Persson, E. Russinova, Nature Plants
1 (2015).
date_created: 2018-12-11T11:51:42Z
date_published: 2015-07-06T00:00:00Z
date_updated: 2021-01-12T06:50:18Z
day: '06'
department:
- _id: JiFr
doi: 10.1038/nplants.2015.94
external_id:
pmid:
- '27250258'
intvolume: ' 1'
issue: '7'
language:
- iso: eng
main_file_link:
- open_access: '1'
url: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4905525/
month: '07'
oa: 1
oa_version: Submitted Version
pmid: 1
publication: Nature Plants
publication_status: published
publisher: Nature Publishing Group
publist_id: '5827'
quality_controlled: '1'
scopus_import: 1
status: public
title: V-ATPase activity in the TGN/EE is required for exocytosis and recycling in
Arabidopsis
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 1
year: '2015'
...
---
_id: '1532'
abstract:
- lang: eng
text: Ammonium is the major nitrogen source in some plant ecosystems but is toxic
at high concentrations, especially when available as the exclusive nitrogen source.
Ammonium stress rapidly leads to various metabolic and hormonal imbalances that
ultimately inhibit root and shoot growth in many plant species, including Arabidopsis
thaliana (L.) Heynh. To identify molecular and genetic factors involved in seedling
survival with prolonged exclusive NH4+ nutrition, a transcriptomic analysis with
microarrays was used. Substantial transcriptional differences were most pronounced
in (NH4)2SO4-grown seedlings, compared with plants grown on KNO3 or NH4NO3. Consistent
with previous physiological analyses, major differences in the expression modules
of photosynthesis-related genes, an altered mitochondrial metabolism, differential
expression of the primary NH4+ assimilation, alteration of transporter gene expression
and crucial changes in cell wall biosynthesis were found. A major difference in
plant hormone responses, particularly of auxin but not cytokinin, was striking.
The activity of the DR5::GUS reporter revealed a dramatically decreased auxin
response in (NH4)2SO4-grown primary roots. The impaired root growth on (NH4)2SO4
was partially rescued by exogenous auxin or in specific mutants in the auxin pathway.
The data suggest that NH4+-induced nutritional and metabolic imbalances can be
partially overcome by elevated auxin levels.
article_processing_charge: No
article_type: original
author:
- first_name: Huaiyu
full_name: Yang, Huaiyu
last_name: Yang
- first_name: Jenny
full_name: Von Der Fecht Bartenbach, Jenny
last_name: Von Der Fecht Bartenbach
- first_name: Jirí
full_name: Friml, Jirí
id: 4159519E-F248-11E8-B48F-1D18A9856A87
last_name: Friml
orcid: 0000-0002-8302-7596
- first_name: Jan
full_name: Lohmann, Jan
last_name: Lohmann
- first_name: Benjamin
full_name: Neuhäuser, Benjamin
last_name: Neuhäuser
- first_name: Uwe
full_name: Ludewig, Uwe
last_name: Ludewig
citation:
ama: Yang H, Von Der Fecht Bartenbach J, Friml J, Lohmann J, Neuhäuser B, Ludewig
U. Auxin-modulated root growth inhibition in Arabidopsis thaliana seedlings with
ammonium as the sole nitrogen source. Functional Plant Biology. 2015;42(3):239-251.
doi:10.1071/FP14171
apa: Yang, H., Von Der Fecht Bartenbach, J., Friml, J., Lohmann, J., Neuhäuser,
B., & Ludewig, U. (2015). Auxin-modulated root growth inhibition in Arabidopsis
thaliana seedlings with ammonium as the sole nitrogen source. Functional Plant
Biology. CSIRO. https://doi.org/10.1071/FP14171
chicago: Yang, Huaiyu, Jenny Von Der Fecht Bartenbach, Jiří Friml, Jan Lohmann,
Benjamin Neuhäuser, and Uwe Ludewig. “Auxin-Modulated Root Growth Inhibition in
Arabidopsis Thaliana Seedlings with Ammonium as the Sole Nitrogen Source.” Functional
Plant Biology. CSIRO, 2015. https://doi.org/10.1071/FP14171.
ieee: H. Yang, J. Von Der Fecht Bartenbach, J. Friml, J. Lohmann, B. Neuhäuser,
and U. Ludewig, “Auxin-modulated root growth inhibition in Arabidopsis thaliana
seedlings with ammonium as the sole nitrogen source,” Functional Plant Biology,
vol. 42, no. 3. CSIRO, pp. 239–251, 2015.
ista: Yang H, Von Der Fecht Bartenbach J, Friml J, Lohmann J, Neuhäuser B, Ludewig
U. 2015. Auxin-modulated root growth inhibition in Arabidopsis thaliana seedlings
with ammonium as the sole nitrogen source. Functional Plant Biology. 42(3), 239–251.
mla: Yang, Huaiyu, et al. “Auxin-Modulated Root Growth Inhibition in Arabidopsis
Thaliana Seedlings with Ammonium as the Sole Nitrogen Source.” Functional Plant
Biology, vol. 42, no. 3, CSIRO, 2015, pp. 239–51, doi:10.1071/FP14171.
short: H. Yang, J. Von Der Fecht Bartenbach, J. Friml, J. Lohmann, B. Neuhäuser,
U. Ludewig, Functional Plant Biology 42 (2015) 239–251.
date_created: 2018-12-11T11:52:34Z
date_published: 2015-03-01T00:00:00Z
date_updated: 2022-05-24T09:02:24Z
day: '01'
department:
- _id: JiFr
doi: 10.1071/FP14171
external_id:
pmid:
- '32480670'
intvolume: ' 42'
issue: '3'
language:
- iso: eng
month: '03'
oa_version: None
page: 239 - 251
pmid: 1
publication: Functional Plant Biology
publication_identifier:
issn:
- 1445-4408
publication_status: published
publisher: CSIRO
publist_id: '5639'
quality_controlled: '1'
scopus_import: '1'
status: public
title: Auxin-modulated root growth inhibition in Arabidopsis thaliana seedlings with
ammonium as the sole nitrogen source
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 42
year: '2015'
...
---
_id: '1534'
abstract:
- lang: eng
text: PIN proteins are auxin export carriers that direct intercellular auxin flow
and in turn regulate many aspects of plant growth and development including responses
to environmental changes. The Arabidopsis R2R3-MYB transcription factor FOUR LIPS
(FLP) and its paralogue MYB88 regulate terminal divisions during stomatal development,
as well as female reproductive development and stress responses. Here we show
that FLP and MYB88 act redundantly but differentially in regulating the transcription
of PIN3 and PIN7 in gravity-sensing cells of primary and lateral roots. On the
one hand, FLP is involved in responses to gravity stimulation in primary roots,
whereas on the other, FLP and MYB88 function complementarily in establishing the
gravitropic set-point angles of lateral roots. Our results support a model in
which FLP and MYB88 expression specifically determines the temporal-spatial patterns
of PIN3 and PIN7 transcription that are closely associated with their preferential
functions during root responses to gravity.
article_number: '8822'
author:
- first_name: Hongzhe
full_name: Wang, Hongzhe
last_name: Wang
- first_name: Kezhen
full_name: Yang, Kezhen
last_name: Yang
- first_name: Junjie
full_name: Zou, Junjie
last_name: Zou
- first_name: Lingling
full_name: Zhu, Lingling
last_name: Zhu
- first_name: Zidian
full_name: Xie, Zidian
last_name: Xie
- first_name: Miyoterao
full_name: Morita, Miyoterao
last_name: Morita
- first_name: Masao
full_name: Tasaka, Masao
last_name: Tasaka
- first_name: Jirí
full_name: Friml, Jirí
id: 4159519E-F248-11E8-B48F-1D18A9856A87
last_name: Friml
orcid: 0000-0002-8302-7596
- first_name: Erich
full_name: Grotewold, Erich
last_name: Grotewold
- first_name: Tom
full_name: Beeckman, Tom
last_name: Beeckman
- first_name: Steffen
full_name: Vanneste, Steffen
last_name: Vanneste
- first_name: Fred
full_name: Sack, Fred
last_name: Sack
- first_name: Jie
full_name: Le, Jie
last_name: Le
citation:
ama: Wang H, Yang K, Zou J, et al. Transcriptional regulation of PIN genes by FOUR
LIPS and MYB88 during Arabidopsis root gravitropism. Nature Communications.
2015;6. doi:10.1038/ncomms9822
apa: Wang, H., Yang, K., Zou, J., Zhu, L., Xie, Z., Morita, M., … Le, J. (2015).
Transcriptional regulation of PIN genes by FOUR LIPS and MYB88 during Arabidopsis
root gravitropism. Nature Communications. Nature Publishing Group. https://doi.org/10.1038/ncomms9822
chicago: Wang, Hongzhe, Kezhen Yang, Junjie Zou, Lingling Zhu, Zidian Xie, Miyoterao
Morita, Masao Tasaka, et al. “Transcriptional Regulation of PIN Genes by FOUR
LIPS and MYB88 during Arabidopsis Root Gravitropism.” Nature Communications.
Nature Publishing Group, 2015. https://doi.org/10.1038/ncomms9822.
ieee: H. Wang et al., “Transcriptional regulation of PIN genes by FOUR LIPS
and MYB88 during Arabidopsis root gravitropism,” Nature Communications,
vol. 6. Nature Publishing Group, 2015.
ista: Wang H, Yang K, Zou J, Zhu L, Xie Z, Morita M, Tasaka M, Friml J, Grotewold
E, Beeckman T, Vanneste S, Sack F, Le J. 2015. Transcriptional regulation of PIN
genes by FOUR LIPS and MYB88 during Arabidopsis root gravitropism. Nature Communications.
6, 8822.
mla: Wang, Hongzhe, et al. “Transcriptional Regulation of PIN Genes by FOUR LIPS
and MYB88 during Arabidopsis Root Gravitropism.” Nature Communications,
vol. 6, 8822, Nature Publishing Group, 2015, doi:10.1038/ncomms9822.
short: H. Wang, K. Yang, J. Zou, L. Zhu, Z. Xie, M. Morita, M. Tasaka, J. Friml,
E. Grotewold, T. Beeckman, S. Vanneste, F. Sack, J. Le, Nature Communications
6 (2015).
date_created: 2018-12-11T11:52:34Z
date_published: 2015-11-18T00:00:00Z
date_updated: 2021-01-12T06:51:26Z
day: '18'
ddc:
- '570'
department:
- _id: JiFr
doi: 10.1038/ncomms9822
ec_funded: 1
file:
- access_level: open_access
checksum: 3c06735fc7cd7e482ca830cbd26001bf
content_type: application/pdf
creator: system
date_created: 2018-12-12T10:17:07Z
date_updated: 2020-07-14T12:45:01Z
file_id: '5259'
file_name: IST-2016-485-v1+1_ncomms9822.pdf
file_size: 1852268
relation: main_file
file_date_updated: 2020-07-14T12:45:01Z
has_accepted_license: '1'
intvolume: ' 6'
language:
- iso: eng
month: '11'
oa: 1
oa_version: Published Version
project:
- _id: 25716A02-B435-11E9-9278-68D0E5697425
call_identifier: FP7
grant_number: '282300'
name: Polarity and subcellular dynamics in plants
publication: Nature Communications
publication_status: published
publisher: Nature Publishing Group
publist_id: '5637'
pubrep_id: '485'
quality_controlled: '1'
scopus_import: 1
status: public
title: Transcriptional regulation of PIN genes by FOUR LIPS and MYB88 during Arabidopsis
root gravitropism
tmp:
image: /images/cc_by.png
legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
short: CC BY (4.0)
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 6
year: '2015'
...