[{"type":"journal_article","status":"public","_id":"5770","department":[{"_id":"FlSc"}],"date_updated":"2023-09-19T09:57:45Z","scopus_import":"1","main_file_link":[{"open_access":"1","url":"https://www.ncbi.nlm.nih.gov/pubmed/30478053"}],"month":"12","intvolume":" 115","abstract":[{"text":"Retroviruses assemble and bud from infected cells in an immature form and require proteolytic maturation for infectivity. The CA (capsid) domains of the Gag polyproteins assemble a protein lattice as a truncated sphere in the immature virion. Proteolytic cleavage of Gag induces dramatic structural rearrangements; a subset of cleaved CA subsequently assembles into the mature core, whose architecture varies among retroviruses. Murine leukemia virus (MLV) is the prototypical γ-retrovirus and serves as the basis of retroviral vectors, but the structure of the MLV CA layer is unknown. Here we have combined X-ray crystallography with cryoelectron tomography to determine the structures of immature and mature MLV CA layers within authentic viral particles. This reveals the structural changes associated with maturation, and, by comparison with HIV-1, uncovers conserved and variable features. In contrast to HIV-1, most MLV CA is used for assembly of the mature core, which adopts variable, multilayered morphologies and does not form a closed structure. Unlike in HIV-1, there is similarity between protein–protein interfaces in the immature MLV CA layer and those in the mature CA layer, and structural maturation of MLV could be achieved through domain rotations that largely maintain hexameric interactions. Nevertheless, the dramatic architectural change on maturation indicates that extensive disassembly and reassembly are required for mature core growth. The core morphology suggests that wrapping of the genome in CA sheets may be sufficient to protect the MLV ribonucleoprotein during cell entry.","lang":"eng"}],"oa_version":"Submitted Version","pmid":1,"volume":115,"issue":"50","publication_identifier":{"issn":["00278424"]},"publication_status":"published","language":[{"iso":"eng"}],"author":[{"first_name":"Kun","full_name":"Qu, Kun","last_name":"Qu"},{"last_name":"Glass","full_name":"Glass, Bärbel","first_name":"Bärbel"},{"first_name":"Michal","full_name":"Doležal, Michal","last_name":"Doležal"},{"last_name":"Schur","orcid":"0000-0003-4790-8078","full_name":"Schur, Florian","first_name":"Florian","id":"48AD8942-F248-11E8-B48F-1D18A9856A87"},{"first_name":"Brice","full_name":"Murciano, Brice","last_name":"Murciano"},{"first_name":"Alan","full_name":"Rein, Alan","last_name":"Rein"},{"first_name":"Michaela","full_name":"Rumlová, Michaela","last_name":"Rumlová"},{"first_name":"Tomáš","full_name":"Ruml, Tomáš","last_name":"Ruml"},{"last_name":"Kräusslich","full_name":"Kräusslich, Hans-Georg","first_name":"Hans-Georg"},{"first_name":"John A. G.","full_name":"Briggs, John A. G.","last_name":"Briggs"}],"external_id":{"isi":["000452866000022"],"pmid":["30478053"]},"article_processing_charge":"No","title":"Structure and architecture of immature and mature murine leukemia virus capsids","citation":{"chicago":"Qu, Kun, Bärbel Glass, Michal Doležal, Florian KM Schur, Brice Murciano, Alan Rein, Michaela Rumlová, Tomáš Ruml, Hans-Georg Kräusslich, and John A. G. Briggs. “Structure and Architecture of Immature and Mature Murine Leukemia Virus Capsids.” Proceedings of the National Academy of Sciences. Proceedings of the National Academy of Sciences, 2018. https://doi.org/10.1073/pnas.1811580115.","ista":"Qu K, Glass B, Doležal M, Schur FK, Murciano B, Rein A, Rumlová M, Ruml T, Kräusslich H-G, Briggs JAG. 2018. Structure and architecture of immature and mature murine leukemia virus capsids. Proceedings of the National Academy of Sciences. 115(50), E11751–E11760.","mla":"Qu, Kun, et al. “Structure and Architecture of Immature and Mature Murine Leukemia Virus Capsids.” Proceedings of the National Academy of Sciences, vol. 115, no. 50, Proceedings of the National Academy of Sciences, 2018, pp. E11751–60, doi:10.1073/pnas.1811580115.","ama":"Qu K, Glass B, Doležal M, et al. Structure and architecture of immature and mature murine leukemia virus capsids. Proceedings of the National Academy of Sciences. 2018;115(50):E11751-E11760. doi:10.1073/pnas.1811580115","apa":"Qu, K., Glass, B., Doležal, M., Schur, F. K., Murciano, B., Rein, A., … Briggs, J. A. G. (2018). Structure and architecture of immature and mature murine leukemia virus capsids. Proceedings of the National Academy of Sciences. Proceedings of the National Academy of Sciences. https://doi.org/10.1073/pnas.1811580115","ieee":"K. Qu et al., “Structure and architecture of immature and mature murine leukemia virus capsids,” Proceedings of the National Academy of Sciences, vol. 115, no. 50. Proceedings of the National Academy of Sciences, pp. E11751–E11760, 2018.","short":"K. Qu, B. Glass, M. Doležal, F.K. Schur, B. Murciano, A. Rein, M. Rumlová, T. Ruml, H.-G. Kräusslich, J.A.G. Briggs, Proceedings of the National Academy of Sciences 115 (2018) E11751–E11760."},"user_id":"c635000d-4b10-11ee-a964-aac5a93f6ac1","quality_controlled":"1","publisher":"Proceedings of the National Academy of Sciences","oa":1,"page":"E11751-E11760","doi":"10.1073/pnas.1811580115","date_published":"2018-12-11T00:00:00Z","date_created":"2018-12-20T21:09:37Z","isi":1,"year":"2018","day":"11","publication":"Proceedings of the National Academy of Sciences"},{"oa_version":"Published Version","abstract":[{"text":"Synthesis is the automated construction of a system from its specification. In real life, hardware and software systems are rarely constructed from scratch. Rather, a system is typically constructed from a library of components. Lustig and Vardi formalized this intuition and studied LTL synthesis from component libraries. In real life, designers seek optimal systems. In this paper we add optimality considerations to the setting. We distinguish between quality considerations (for example, size - the smaller a system is, the better it is), and pricing (for example, the payment to the company who manufactured the component). We study the problem of designing systems with minimal quality-cost and price. A key point is that while the quality cost is individual - the choices of a designer are independent of choices made by other designers that use the same library, pricing gives rise to a resource-allocation game - designers that use the same component share its price, with the share being proportional to the number of uses (a component can be used several times in a design). We study both closed and open settings, and in both we solve the problem of finding an optimal design. In a setting with multiple designers, we also study the game-theoretic problems of the induced resource-allocation game.","lang":"eng"}],"intvolume":" 712","month":"02","main_file_link":[{"open_access":"1","url":"http://citeseerx.ist.psu.edu/viewdoc/summary?doi=10.1.1.636.4529"}],"scopus_import":"1","language":[{"iso":"eng"}],"publication_status":"published","ec_funded":1,"volume":712,"_id":"608","status":"public","type":"journal_article","article_type":"original","date_updated":"2023-09-19T10:00:21Z","department":[{"_id":"ToHe"}],"oa":1,"publisher":"Elsevier","quality_controlled":"1","publication":"Theoretical Computer Science","day":"15","year":"2018","isi":1,"date_created":"2018-12-11T11:47:28Z","date_published":"2018-02-15T00:00:00Z","doi":"10.1016/j.tcs.2017.11.001","page":"50 - 72","project":[{"call_identifier":"FP7","_id":"25EE3708-B435-11E9-9278-68D0E5697425","name":"Quantitative Reactive Modeling","grant_number":"267989"},{"_id":"25832EC2-B435-11E9-9278-68D0E5697425","call_identifier":"FWF","grant_number":"S 11407_N23","name":"Rigorous Systems Engineering"},{"call_identifier":"FWF","_id":"25F42A32-B435-11E9-9278-68D0E5697425","grant_number":"Z211","name":"The Wittgenstein Prize"}],"user_id":"c635000d-4b10-11ee-a964-aac5a93f6ac1","citation":{"mla":"Avni, Guy, and Orna Kupferman. “Synthesis from Component Libraries with Costs.” Theoretical Computer Science, vol. 712, Elsevier, 2018, pp. 50–72, doi:10.1016/j.tcs.2017.11.001.","apa":"Avni, G., & Kupferman, O. (2018). Synthesis from component libraries with costs. Theoretical Computer Science. Elsevier. https://doi.org/10.1016/j.tcs.2017.11.001","ama":"Avni G, Kupferman O. Synthesis from component libraries with costs. Theoretical Computer Science. 2018;712:50-72. doi:10.1016/j.tcs.2017.11.001","short":"G. Avni, O. Kupferman, Theoretical Computer Science 712 (2018) 50–72.","ieee":"G. Avni and O. Kupferman, “Synthesis from component libraries with costs,” Theoretical Computer Science, vol. 712. Elsevier, pp. 50–72, 2018.","chicago":"Avni, Guy, and Orna Kupferman. “Synthesis from Component Libraries with Costs.” Theoretical Computer Science. Elsevier, 2018. https://doi.org/10.1016/j.tcs.2017.11.001.","ista":"Avni G, Kupferman O. 2018. Synthesis from component libraries with costs. Theoretical Computer Science. 712, 50–72."},"title":"Synthesis from component libraries with costs","external_id":{"isi":["000424959200003"]},"article_processing_charge":"No","publist_id":"7197","author":[{"first_name":"Guy","id":"463C8BC2-F248-11E8-B48F-1D18A9856A87","last_name":"Avni","full_name":"Avni, Guy","orcid":"0000-0001-5588-8287"},{"full_name":"Kupferman, Orna","last_name":"Kupferman","first_name":"Orna"}]},{"publication_status":"published","language":[{"iso":"eng"}],"issue":"6","volume":55,"abstract":[{"lang":"eng","text":"Although dopamine receptors D1 and D2 play key roles in hippocampal function, their synaptic localization within the hippocampus has not been fully elucidated. In order to understand precise functions of pre- or postsynaptic dopamine receptors (DRs), the development of protocols to differentiate pre- and postsynaptic DRs is essential. So far, most studies on determination and quantification of DRs did not discriminate between subsynaptic localization. Therefore, the aim of the study was to generate a robust workflow for the localization of DRs. This work provides the basis for future work on hippocampal DRs, in light that DRs may have different functions at pre- or postsynaptic sites. Synaptosomes from rat hippocampi isolated by a sucrose gradient protocol were prepared for super-resolution direct stochastic optical reconstruction microscopy (dSTORM) using Bassoon as a presynaptic zone and Homer1 as postsynaptic density marker. Direct labeling of primary validated antibodies against dopamine receptors D1 (D1R) and D2 (D2R) with Alexa Fluor 594 enabled unequivocal assignment of D1R and D2R to both, pre- and postsynaptic sites. D1R immunoreactivity clusters were observed within the presynaptic active zone as well as at perisynaptic sites at the edge of the presynaptic active zone. The results may be useful for the interpretation of previous studies and the design of future work on DRs in the hippocampus. Moreover, the reduction of the complexity of brain tissue by the use of synaptosomal preparations and dSTORM technology may represent a useful tool for synaptic localization of brain proteins."}],"oa_version":"None","scopus_import":"1","intvolume":" 55","month":"06","date_updated":"2023-09-19T09:58:11Z","department":[{"_id":"RySh"}],"_id":"705","type":"journal_article","status":"public","year":"2018","isi":1,"publication":"Molecular Neurobiology","day":"01","page":"4857 – 4869","date_created":"2018-12-11T11:48:02Z","date_published":"2018-06-01T00:00:00Z","doi":"10.1007/s12035-017-0688-y","publisher":"Springer","quality_controlled":"1","citation":{"ista":"Miklosi A, Del Favero G, Bulat T, Höger H, Shigemoto R, Marko D, Lubec G. 2018. Super resolution microscopical localization of dopamine receptors 1 and 2 in rat hippocampal synaptosomes. Molecular Neurobiology. 55(6), 4857 – 4869.","chicago":"Miklosi, Andras, Giorgia Del Favero, Tanja Bulat, Harald Höger, Ryuichi Shigemoto, Doris Marko, and Gert Lubec. “Super Resolution Microscopical Localization of Dopamine Receptors 1 and 2 in Rat Hippocampal Synaptosomes.” Molecular Neurobiology. Springer, 2018. https://doi.org/10.1007/s12035-017-0688-y.","ama":"Miklosi A, Del Favero G, Bulat T, et al. Super resolution microscopical localization of dopamine receptors 1 and 2 in rat hippocampal synaptosomes. Molecular Neurobiology. 2018;55(6):4857 – 4869. doi:10.1007/s12035-017-0688-y","apa":"Miklosi, A., Del Favero, G., Bulat, T., Höger, H., Shigemoto, R., Marko, D., & Lubec, G. (2018). Super resolution microscopical localization of dopamine receptors 1 and 2 in rat hippocampal synaptosomes. Molecular Neurobiology. Springer. https://doi.org/10.1007/s12035-017-0688-y","ieee":"A. Miklosi et al., “Super resolution microscopical localization of dopamine receptors 1 and 2 in rat hippocampal synaptosomes,” Molecular Neurobiology, vol. 55, no. 6. Springer, pp. 4857 – 4869, 2018.","short":"A. Miklosi, G. Del Favero, T. Bulat, H. Höger, R. Shigemoto, D. Marko, G. Lubec, Molecular Neurobiology 55 (2018) 4857 – 4869.","mla":"Miklosi, Andras, et al. “Super Resolution Microscopical Localization of Dopamine Receptors 1 and 2 in Rat Hippocampal Synaptosomes.” Molecular Neurobiology, vol. 55, no. 6, Springer, 2018, pp. 4857 – 4869, doi:10.1007/s12035-017-0688-y."},"user_id":"c635000d-4b10-11ee-a964-aac5a93f6ac1","external_id":{"isi":["000431991500025"]},"article_processing_charge":"No","publist_id":"6991","author":[{"last_name":"Miklosi","full_name":"Miklosi, Andras","first_name":"Andras"},{"first_name":"Giorgia","full_name":"Del Favero, Giorgia","last_name":"Del Favero"},{"last_name":"Bulat","full_name":"Bulat, Tanja","first_name":"Tanja"},{"first_name":"Harald","full_name":"Höger, Harald","last_name":"Höger"},{"id":"499F3ABC-F248-11E8-B48F-1D18A9856A87","first_name":"Ryuichi","last_name":"Shigemoto","orcid":"0000-0001-8761-9444","full_name":"Shigemoto, Ryuichi"},{"last_name":"Marko","full_name":"Marko, Doris","first_name":"Doris"},{"last_name":"Lubec","full_name":"Lubec, Gert","first_name":"Gert"}],"title":"Super resolution microscopical localization of dopamine receptors 1 and 2 in rat hippocampal synaptosomes"},{"article_processing_charge":"No","external_id":{"isi":["000438482800019"],"pmid":["30007417"]},"author":[{"last_name":"Nishiyama","full_name":"Nishiyama, Tomoaki","first_name":"Tomoaki"},{"last_name":"Sakayama","full_name":"Sakayama, Hidetoshi","first_name":"Hidetoshi"},{"last_name":"De Vries","full_name":"De Vries, Jan","first_name":"Jan"},{"first_name":"Henrik","last_name":"Buschmann","full_name":"Buschmann, Henrik"},{"first_name":"Denis","last_name":"Saint Marcoux","full_name":"Saint Marcoux, Denis"},{"first_name":"Kristian","last_name":"Ullrich","full_name":"Ullrich, Kristian"},{"full_name":"Haas, Fabian","last_name":"Haas","first_name":"Fabian"},{"full_name":"Vanderstraeten, Lisa","last_name":"Vanderstraeten","first_name":"Lisa"},{"full_name":"Becker, Dirk","last_name":"Becker","first_name":"Dirk"},{"first_name":"Daniel","last_name":"Lang","full_name":"Lang, Daniel"},{"full_name":"Vosolsobě, Stanislav","last_name":"Vosolsobě","first_name":"Stanislav"},{"full_name":"Rombauts, Stephane","last_name":"Rombauts","first_name":"Stephane"},{"first_name":"Per","full_name":"Wilhelmsson, Per","last_name":"Wilhelmsson"},{"full_name":"Janitza, Philipp","last_name":"Janitza","first_name":"Philipp"},{"last_name":"Kern","full_name":"Kern, Ramona","first_name":"Ramona"},{"last_name":"Heyl","full_name":"Heyl, Alexander","first_name":"Alexander"},{"first_name":"Florian","last_name":"Rümpler","full_name":"Rümpler, Florian"},{"last_name":"Calderón Villalobos","full_name":"Calderón Villalobos, Luz","first_name":"Luz"},{"full_name":"Clay, John","last_name":"Clay","first_name":"John"},{"full_name":"Skokan, Roman","last_name":"Skokan","first_name":"Roman"},{"first_name":"Atsushi","full_name":"Toyoda, Atsushi","last_name":"Toyoda"},{"last_name":"Suzuki","full_name":"Suzuki, Yutaka","first_name":"Yutaka"},{"full_name":"Kagoshima, Hiroshi","last_name":"Kagoshima","first_name":"Hiroshi"},{"first_name":"Elio","full_name":"Schijlen, Elio","last_name":"Schijlen"},{"first_name":"Navindra","full_name":"Tajeshwar, Navindra","last_name":"Tajeshwar"},{"first_name":"Bruno","last_name":"Catarino","full_name":"Catarino, Bruno"},{"first_name":"Alexander","full_name":"Hetherington, Alexander","last_name":"Hetherington"},{"last_name":"Saltykova","full_name":"Saltykova, Assia","first_name":"Assia"},{"last_name":"Bonnot","full_name":"Bonnot, Clemence","first_name":"Clemence"},{"first_name":"Holger","full_name":"Breuninger, Holger","last_name":"Breuninger"},{"full_name":"Symeonidi, Aikaterini","last_name":"Symeonidi","first_name":"Aikaterini"},{"first_name":"Guru","full_name":"Radhakrishnan, Guru","last_name":"Radhakrishnan"},{"first_name":"Filip","full_name":"Van Nieuwerburgh, Filip","last_name":"Van Nieuwerburgh"},{"full_name":"Deforce, Dieter","last_name":"Deforce","first_name":"Dieter"},{"full_name":"Chang, Caren","last_name":"Chang","first_name":"Caren"},{"full_name":"Karol, Kenneth","last_name":"Karol","first_name":"Kenneth"},{"last_name":"Hedrich","full_name":"Hedrich, Rainer","first_name":"Rainer"},{"first_name":"Peter","full_name":"Ulvskov, Peter","last_name":"Ulvskov"},{"first_name":"Gernot","last_name":"Glöckner","full_name":"Glöckner, Gernot"},{"first_name":"Charles","full_name":"Delwiche, Charles","last_name":"Delwiche"},{"last_name":"Petrášek","full_name":"Petrášek, Jan","first_name":"Jan"},{"last_name":"Van De Peer","full_name":"Van De Peer, Yves","first_name":"Yves"},{"full_name":"Friml, Jirí","orcid":"0000-0002-8302-7596","last_name":"Friml","first_name":"Jirí","id":"4159519E-F248-11E8-B48F-1D18A9856A87"},{"first_name":"Mary","last_name":"Beilby","full_name":"Beilby, Mary"},{"first_name":"Liam","last_name":"Dolan","full_name":"Dolan, Liam"},{"full_name":"Kohara, Yuji","last_name":"Kohara","first_name":"Yuji"},{"first_name":"Sumio","full_name":"Sugano, Sumio","last_name":"Sugano"},{"last_name":"Fujiyama","full_name":"Fujiyama, Asao","first_name":"Asao"},{"full_name":"Delaux, Pierre Marc","last_name":"Delaux","first_name":"Pierre Marc"},{"first_name":"Marcel","last_name":"Quint","full_name":"Quint, Marcel"},{"first_name":"Gunter","last_name":"Theissen","full_name":"Theissen, Gunter"},{"full_name":"Hagemann, Martin","last_name":"Hagemann","first_name":"Martin"},{"first_name":"Jesper","last_name":"Harholt","full_name":"Harholt, Jesper"},{"full_name":"Dunand, Christophe","last_name":"Dunand","first_name":"Christophe"},{"full_name":"Zachgo, Sabine","last_name":"Zachgo","first_name":"Sabine"},{"full_name":"Langdale, Jane","last_name":"Langdale","first_name":"Jane"},{"first_name":"Florian","full_name":"Maumus, Florian","last_name":"Maumus"},{"first_name":"Dominique","full_name":"Van Der Straeten, Dominique","last_name":"Van Der Straeten"},{"last_name":"Gould","full_name":"Gould, Sven B","first_name":"Sven B"},{"last_name":"Rensing","full_name":"Rensing, Stefan","first_name":"Stefan"}],"publist_id":"7774","title":"The Chara genome: Secondary complexity and implications for plant terrestrialization","citation":{"chicago":"Nishiyama, Tomoaki, Hidetoshi Sakayama, Jan De Vries, Henrik Buschmann, Denis Saint Marcoux, Kristian Ullrich, Fabian Haas, et al. “The Chara Genome: Secondary Complexity and Implications for Plant Terrestrialization.” Cell. Cell Press, 2018. https://doi.org/10.1016/j.cell.2018.06.033.","ista":"Nishiyama T, Sakayama H, De Vries J, Buschmann H, Saint Marcoux D, Ullrich K, Haas F, Vanderstraeten L, Becker D, Lang D, Vosolsobě S, Rombauts S, Wilhelmsson P, Janitza P, Kern R, Heyl A, Rümpler F, Calderón Villalobos L, Clay J, Skokan R, Toyoda A, Suzuki Y, Kagoshima H, Schijlen E, Tajeshwar N, Catarino B, Hetherington A, Saltykova A, Bonnot C, Breuninger H, Symeonidi A, Radhakrishnan G, Van Nieuwerburgh F, Deforce D, Chang C, Karol K, Hedrich R, Ulvskov P, Glöckner G, Delwiche C, Petrášek J, Van De Peer Y, Friml J, Beilby M, Dolan L, Kohara Y, Sugano S, Fujiyama A, Delaux PM, Quint M, Theissen G, Hagemann M, Harholt J, Dunand C, Zachgo S, Langdale J, Maumus F, Van Der Straeten D, Gould SB, Rensing S. 2018. The Chara genome: Secondary complexity and implications for plant terrestrialization. Cell. 174(2), 448–464.e24.","mla":"Nishiyama, Tomoaki, et al. “The Chara Genome: Secondary Complexity and Implications for Plant Terrestrialization.” Cell, vol. 174, no. 2, Cell Press, 2018, p. 448–464.e24, doi:10.1016/j.cell.2018.06.033.","ama":"Nishiyama T, Sakayama H, De Vries J, et al. The Chara genome: Secondary complexity and implications for plant terrestrialization. Cell. 2018;174(2):448-464.e24. doi:10.1016/j.cell.2018.06.033","apa":"Nishiyama, T., Sakayama, H., De Vries, J., Buschmann, H., Saint Marcoux, D., Ullrich, K., … Rensing, S. (2018). The Chara genome: Secondary complexity and implications for plant terrestrialization. Cell. Cell Press. https://doi.org/10.1016/j.cell.2018.06.033","short":"T. Nishiyama, H. Sakayama, J. De Vries, H. Buschmann, D. Saint Marcoux, K. Ullrich, F. Haas, L. Vanderstraeten, D. Becker, D. Lang, S. Vosolsobě, S. Rombauts, P. Wilhelmsson, P. Janitza, R. Kern, A. Heyl, F. Rümpler, L. Calderón Villalobos, J. Clay, R. Skokan, A. Toyoda, Y. Suzuki, H. Kagoshima, E. Schijlen, N. Tajeshwar, B. Catarino, A. Hetherington, A. Saltykova, C. Bonnot, H. Breuninger, A. Symeonidi, G. Radhakrishnan, F. Van Nieuwerburgh, D. Deforce, C. Chang, K. Karol, R. Hedrich, P. Ulvskov, G. Glöckner, C. Delwiche, J. Petrášek, Y. Van De Peer, J. Friml, M. Beilby, L. Dolan, Y. Kohara, S. Sugano, A. Fujiyama, P.M. Delaux, M. Quint, G. Theissen, M. Hagemann, J. Harholt, C. Dunand, S. Zachgo, J. Langdale, F. Maumus, D. Van Der Straeten, S.B. Gould, S. Rensing, Cell 174 (2018) 448–464.e24.","ieee":"T. Nishiyama et al., “The Chara genome: Secondary complexity and implications for plant terrestrialization,” Cell, vol. 174, no. 2. Cell Press, p. 448–464.e24, 2018."},"user_id":"c635000d-4b10-11ee-a964-aac5a93f6ac1","project":[{"grant_number":"742985","name":"Tracing Evolution of Auxin Transport and Polarity in Plants","_id":"261099A6-B435-11E9-9278-68D0E5697425","call_identifier":"H2020"}],"page":"448 - 464.e24","date_created":"2018-12-11T11:44:53Z","date_published":"2018-07-12T00:00:00Z","doi":"10.1016/j.cell.2018.06.033","year":"2018","isi":1,"publication":"Cell","day":"12","oa":1,"quality_controlled":"1","publisher":"Cell Press","acknowledgement":"In-Data-Review","department":[{"_id":"JiFr"}],"date_updated":"2023-09-19T10:02:47Z","type":"journal_article","status":"public","_id":"148","ec_funded":1,"volume":174,"issue":"2","publication_status":"published","language":[{"iso":"eng"}],"main_file_link":[{"url":"https://www.ncbi.nlm.nih.gov/pubmed/30007417","open_access":"1"}],"scopus_import":"1","intvolume":" 174","month":"07","abstract":[{"lang":"eng","text":"Land plants evolved from charophytic algae, among which Charophyceae possess the most complex body plans. We present the genome of Chara braunii; comparison of the genome to those of land plants identified evolutionary novelties for plant terrestrialization and land plant heritage genes. C. braunii employs unique xylan synthases for cell wall biosynthesis, a phragmoplast (cell separation) mechanism similar to that of land plants, and many phytohormones. C. braunii plastids are controlled via land-plant-like retrograde signaling, and transcriptional regulation is more elaborate than in other algae. The morphological complexity of this organism may result from expanded gene families, with three cases of particular note: genes effecting tolerance to reactive oxygen species (ROS), LysM receptor-like kinases, and transcription factors (TFs). Transcriptomic analysis of sexual reproductive structures reveals intricate control by TFs, activity of the ROS gene network, and the ancestral use of plant-like storage and stress protection proteins in the zygote."}],"pmid":1,"oa_version":"Published Version"},{"publist_id":"7426","author":[{"last_name":"Cavallari","full_name":"Cavallari, Nicola","first_name":"Nicola","id":"457160E6-F248-11E8-B48F-1D18A9856A87"},{"last_name":"Nibau","full_name":"Nibau, Candida","first_name":"Candida"},{"last_name":"Fuchs","full_name":"Fuchs, Armin","first_name":"Armin"},{"first_name":"Despoina","full_name":"Dadarou, Despoina","last_name":"Dadarou"},{"last_name":"Barta","full_name":"Barta, Andrea","first_name":"Andrea"},{"first_name":"John","last_name":"Doonan","full_name":"Doonan, John"}],"article_processing_charge":"No","external_id":{"isi":["000434365500008"]},"title":"The cyclin‐dependent kinase G group defines a thermo‐sensitive alternative splicing circuit modulating the expression of Arabidopsis ATU 2AF 65A","citation":{"ieee":"N. Cavallari, C. Nibau, A. Fuchs, D. Dadarou, A. Barta, and J. Doonan, “The cyclin‐dependent kinase G group defines a thermo‐sensitive alternative splicing circuit modulating the expression of Arabidopsis ATU 2AF 65A,” The Plant Journal, vol. 94, no. 6. Wiley, pp. 1010–1022, 2018.","short":"N. Cavallari, C. Nibau, A. Fuchs, D. Dadarou, A. Barta, J. Doonan, The Plant Journal 94 (2018) 1010–1022.","ama":"Cavallari N, Nibau C, Fuchs A, Dadarou D, Barta A, Doonan J. The cyclin‐dependent kinase G group defines a thermo‐sensitive alternative splicing circuit modulating the expression of Arabidopsis ATU 2AF 65A. The Plant Journal. 2018;94(6):1010-1022. doi:10.1111/tpj.13914","apa":"Cavallari, N., Nibau, C., Fuchs, A., Dadarou, D., Barta, A., & Doonan, J. (2018). The cyclin‐dependent kinase G group defines a thermo‐sensitive alternative splicing circuit modulating the expression of Arabidopsis ATU 2AF 65A. The Plant Journal. Wiley. https://doi.org/10.1111/tpj.13914","mla":"Cavallari, Nicola, et al. “The Cyclin‐dependent Kinase G Group Defines a Thermo‐sensitive Alternative Splicing Circuit Modulating the Expression of Arabidopsis ATU 2AF 65A.” The Plant Journal, vol. 94, no. 6, Wiley, 2018, pp. 1010–22, doi:10.1111/tpj.13914.","ista":"Cavallari N, Nibau C, Fuchs A, Dadarou D, Barta A, Doonan J. 2018. The cyclin‐dependent kinase G group defines a thermo‐sensitive alternative splicing circuit modulating the expression of Arabidopsis ATU 2AF 65A. The Plant Journal. 94(6), 1010–1022.","chicago":"Cavallari, Nicola, Candida Nibau, Armin Fuchs, Despoina Dadarou, Andrea Barta, and John Doonan. “The Cyclin‐dependent Kinase G Group Defines a Thermo‐sensitive Alternative Splicing Circuit Modulating the Expression of Arabidopsis ATU 2AF 65A.” The Plant Journal. Wiley, 2018. https://doi.org/10.1111/tpj.13914."},"user_id":"c635000d-4b10-11ee-a964-aac5a93f6ac1","page":"1010 - 1022","doi":"10.1111/tpj.13914","date_published":"2018-06-01T00:00:00Z","date_created":"2018-12-11T11:46:17Z","isi":1,"has_accepted_license":"1","year":"2018","day":"01","publication":"The Plant Journal","quality_controlled":"1","publisher":"Wiley","oa":1,"acknowledgement":"CN, DD and JHD were funded by the BBSRC (grant number BB/M009459/1). NC was funded by the VIPS Program of the Austrian Federal Ministry of Science and Research and the City of Vienna. AB and AF were supported by the Austrian Science Fund (FWF) [DK W1207; SFB RNAreg F43-P10]","department":[{"_id":"EvBe"}],"file_date_updated":"2020-07-14T12:46:22Z","date_updated":"2023-09-19T10:07:08Z","ddc":["580"],"type":"journal_article","tmp":{"legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode","image":"/images/cc_by.png","name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)","short":"CC BY (4.0)"},"status":"public","_id":"403","volume":94,"issue":"6","publication_status":"published","file":[{"relation":"main_file","access_level":"open_access","content_type":"application/pdf","file_id":"5934","checksum":"d9d3ad3215ac0e581731443fca312266","creator":"dernst","file_size":1543354,"date_updated":"2020-07-14T12:46:22Z","file_name":"2018_PlantJourn_Cavallari.pdf","date_created":"2019-02-06T11:40:54Z"}],"language":[{"iso":"eng"}],"scopus_import":"1","month":"06","intvolume":" 94","abstract":[{"text":"The ability to adapt growth and development to temperature variations is crucial to generate plant varieties resilient to predicted temperature changes. However, the mechanisms underlying plant response to progressive increases in temperature have just started to be elucidated. Here, we report that the Cyclin-dependent Kinase G1 (CDKG1) is a central element in a thermo-sensitive mRNA splicing cascade that transduces changes in ambient temperature into differential expression of the fundamental spliceosome component, ATU2AF65A. CDKG1 is alternatively spliced in a temperature-dependent manner. We found that this process is partly dependent on both the Cyclin-dependent Kinase G2 (CDKG2) and the interacting co-factor CYCLIN L1 resulting in two distinct messenger RNAs. Relative abundance of both CDKG1 transcripts correlates with ambient temperature and possibly with different expression levels of the associated protein isoforms. Both CDKG1 alternative transcripts are necessary to fully complement the expression of ATU2AF65A across the temperature range. Our data support a previously unidentified temperature-dependent mechanism based on the alternative splicing of CDKG1 and regulated by CDKG2 and CYCLIN L1. We propose that changes in ambient temperature affect the relative abundance of CDKG1 transcripts and this in turn translates into differential CDKG1 protein expression coordinating the alternative splicing of ATU2AF65A. This article is protected by copyright. All rights reserved.","lang":"eng"}],"oa_version":"Published Version"},{"day":"12","year":"2018","has_accepted_license":"1","isi":1,"date_created":"2018-12-11T11:44:55Z","date_published":"2018-07-12T00:00:00Z","doi":"10.1007/978-3-319-95582-7_9","page":"147 - 164","oa":1,"quality_controlled":"1","publisher":"Springer","user_id":"c635000d-4b10-11ee-a964-aac5a93f6ac1","citation":{"short":"T. Ferrere, in:, Springer, 2018, pp. 147–164.","ieee":"T. Ferrere, “The compound interest in relaxing punctuality,” presented at the FM: International Symposium on Formal Methods, Oxford, UK, 2018, vol. 10951, pp. 147–164.","ama":"Ferrere T. The compound interest in relaxing punctuality. In: Vol 10951. Springer; 2018:147-164. doi:10.1007/978-3-319-95582-7_9","apa":"Ferrere, T. (2018). The compound interest in relaxing punctuality (Vol. 10951, pp. 147–164). Presented at the FM: International Symposium on Formal Methods, Oxford, UK: Springer. https://doi.org/10.1007/978-3-319-95582-7_9","mla":"Ferrere, Thomas. The Compound Interest in Relaxing Punctuality. Vol. 10951, Springer, 2018, pp. 147–64, doi:10.1007/978-3-319-95582-7_9.","ista":"Ferrere T. 2018. The compound interest in relaxing punctuality. FM: International Symposium on Formal Methods, LNCS, vol. 10951, 147–164.","chicago":"Ferrere, Thomas. “The Compound Interest in Relaxing Punctuality,” 10951:147–64. Springer, 2018. https://doi.org/10.1007/978-3-319-95582-7_9."},"title":"The compound interest in relaxing punctuality","external_id":{"isi":["000489765800009"]},"article_processing_charge":"No","author":[{"id":"40960E6E-F248-11E8-B48F-1D18A9856A87","first_name":"Thomas","last_name":"Ferrere","full_name":"Ferrere, Thomas","orcid":"0000-0001-5199-3143"}],"publist_id":"7765","project":[{"grant_number":"Z211","name":"The Wittgenstein Prize","call_identifier":"FWF","_id":"25F42A32-B435-11E9-9278-68D0E5697425"},{"grant_number":"S 11407_N23","name":"Rigorous Systems Engineering","_id":"25832EC2-B435-11E9-9278-68D0E5697425","call_identifier":"FWF"}],"language":[{"iso":"eng"}],"file":[{"date_created":"2020-10-09T06:22:41Z","file_name":"2018_LNCS_Ferrere.pdf","date_updated":"2020-10-09T06:22:41Z","file_size":485576,"creator":"dernst","checksum":"a045c213c42c445f1889326f8db82a0a","file_id":"8637","success":1,"content_type":"application/pdf","access_level":"open_access","relation":"main_file"}],"publication_status":"published","volume":10951,"oa_version":"Submitted Version","abstract":[{"lang":"eng","text":"Imprecision in timing can sometimes be beneficial: Metric interval temporal logic (MITL), disabling the expression of punctuality constraints, was shown to translate to timed automata, yielding an elementary decision procedure. We show how this principle extends to other forms of dense-time specification using regular expressions. By providing a clean, automaton-based formal framework for non-punctual languages, we are able to recover and extend several results in timed systems. Metric interval regular expressions (MIRE) are introduced, providing regular expressions with non-singular duration constraints. We obtain that MIRE are expressively complete relative to a class of one-clock timed automata, which can be determinized using additional clocks. Metric interval dynamic logic (MIDL) is then defined using MIRE as temporal modalities. We show that MIDL generalizes known extensions of MITL, while translating to timed automata at comparable cost."}],"intvolume":" 10951","month":"07","scopus_import":"1","alternative_title":["LNCS"],"ddc":["000"],"date_updated":"2023-09-19T10:05:37Z","file_date_updated":"2020-10-09T06:22:41Z","department":[{"_id":"ToHe"}],"_id":"156","status":"public","conference":{"start_date":"2018-07-15","location":"Oxford, UK","end_date":"2018-07-17","name":"FM: International Symposium on Formal Methods"},"type":"conference"},{"year":"2018","has_accepted_license":"1","isi":1,"publication":"Molecular Plant Pathology","day":"01","page":"2277 - 2287","date_created":"2018-12-11T11:44:39Z","date_published":"2018-10-01T00:00:00Z","doi":"10.1111/mpp.12698","acknowledgement":"the Austrian Science Fund (FWF): [P27429‐B22, P27818‐B22, I 3033‐B22], and the Austrian Academy of Science (OEAW).","oa":1,"publisher":"Wiley","quality_controlled":"1","citation":{"chicago":"Seitner, Denise, Simon Uhse, Michelle C Gallei, and Armin Djamei. “The Core Effector Cce1 Is Required for Early Infection of Maize by Ustilago Maydis.” Molecular Plant Pathology. Wiley, 2018. https://doi.org/10.1111/mpp.12698.","ista":"Seitner D, Uhse S, Gallei MC, Djamei A. 2018. The core effector Cce1 is required for early infection of maize by Ustilago maydis. Molecular Plant Pathology. 19(10), 2277–2287.","mla":"Seitner, Denise, et al. “The Core Effector Cce1 Is Required for Early Infection of Maize by Ustilago Maydis.” Molecular Plant Pathology, vol. 19, no. 10, Wiley, 2018, pp. 2277–87, doi:10.1111/mpp.12698.","short":"D. Seitner, S. Uhse, M.C. Gallei, A. Djamei, Molecular Plant Pathology 19 (2018) 2277–2287.","ieee":"D. Seitner, S. Uhse, M. C. Gallei, and A. Djamei, “The core effector Cce1 is required for early infection of maize by Ustilago maydis,” Molecular Plant Pathology, vol. 19, no. 10. Wiley, pp. 2277–2287, 2018.","apa":"Seitner, D., Uhse, S., Gallei, M. C., & Djamei, A. (2018). The core effector Cce1 is required for early infection of maize by Ustilago maydis. Molecular Plant Pathology. Wiley. https://doi.org/10.1111/mpp.12698","ama":"Seitner D, Uhse S, Gallei MC, Djamei A. The core effector Cce1 is required for early infection of maize by Ustilago maydis. Molecular Plant Pathology. 2018;19(10):2277-2287. doi:10.1111/mpp.12698"},"user_id":"c635000d-4b10-11ee-a964-aac5a93f6ac1","external_id":{"isi":["000445624100006"]},"article_processing_charge":"No","author":[{"first_name":"Denise","last_name":"Seitner","full_name":"Seitner, Denise"},{"first_name":"Simon","last_name":"Uhse","full_name":"Uhse, Simon"},{"id":"35A03822-F248-11E8-B48F-1D18A9856A87","first_name":"Michelle C","full_name":"Gallei, Michelle C","orcid":"0000-0003-1286-7368","last_name":"Gallei"},{"full_name":"Djamei, Armin","last_name":"Djamei","first_name":"Armin"}],"publist_id":"7950","title":"The core effector Cce1 is required for early infection of maize by Ustilago maydis","publication_status":"published","language":[{"iso":"eng"}],"file":[{"success":1,"file_id":"5740","relation":"main_file","access_level":"open_access","content_type":"application/pdf","file_name":"2018_MolecPlantPath_Seitner.pdf","date_created":"2018-12-18T09:46:00Z","creator":"dernst","file_size":682335,"date_updated":"2018-12-18T09:46:00Z"}],"issue":"10","volume":19,"abstract":[{"text":"The biotrophic pathogen Ustilago maydis, the causative agent of corn smut disease, infects one of the most important crops worldwide – Zea mays. To successfully colonize its host, U. maydis secretes proteins, known as effectors, that suppress plant defense responses and facilitate the establishment of biotrophy. In this work, we describe the U. maydis effector protein Cce1. Cce1 is essential for virulence and is upregulated during infection. Through microscopic analysis and in vitro assays, we show that Cce1 is secreted from hyphae during filamentous growth of the fungus. Strikingly, Δcce1 mutants are blocked at early stages of infection and induce callose deposition as a plant defense response. Cce1 is highly conserved among smut fungi and the Ustilago bromivora ortholog complemented the virulence defect of the SG200Δcce1 deletion strain. These data indicate that Cce1 is a core effector with apoplastic localization that is essential for U. maydis to infect its host.","lang":"eng"}],"oa_version":"Published Version","scopus_import":"1","intvolume":" 19","month":"10","date_updated":"2023-09-19T10:06:42Z","ddc":["580"],"file_date_updated":"2018-12-18T09:46:00Z","department":[{"_id":"GradSch"}],"_id":"104","tmp":{"legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode","image":"/images/cc_by.png","name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)","short":"CC BY (4.0)"},"type":"journal_article","status":"public"},{"issue":"24","volume":27,"related_material":{"record":[{"status":"public","id":"9805","relation":"research_data"}]},"language":[{"iso":"eng"}],"file":[{"creator":"apreinsp","date_updated":"2020-07-14T12:46:22Z","file_size":295452,"date_created":"2019-07-19T06:54:46Z","file_name":"2018_MolecularEcology_BartonNick.pdf","access_level":"open_access","relation":"main_file","content_type":"application/pdf","file_id":"6652"}],"publication_status":"published","publication_identifier":{"issn":["1365294X"]},"intvolume":" 27","month":"12","scopus_import":"1","oa_version":"Published Version","pmid":1,"abstract":[{"text":"Hanemaaijer et al. (Molecular Ecology, 27, 2018) describe the genetic consequences of the introgression of an insecticide resistance allele into a mosquito population. Linked alleles initially increased, but many of these later declined. It is hard to determine whether this decline was due to counter‐selection, rather than simply to chance.","lang":"eng"}],"department":[{"_id":"NiBa"}],"file_date_updated":"2020-07-14T12:46:22Z","ddc":["576"],"date_updated":"2023-09-19T10:06:08Z","status":"public","tmp":{"legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode","image":"/images/cc_by.png","name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)","short":"CC BY (4.0)"},"type":"journal_article","article_type":"letter_note","_id":"40","date_created":"2018-12-11T11:44:18Z","date_published":"2018-12-31T00:00:00Z","doi":"10.1111/mec.14950","page":"4973-4975","publication":"Molecular Ecology","day":"31","year":"2018","has_accepted_license":"1","isi":1,"oa":1,"quality_controlled":"1","publisher":"Wiley","title":"The consequences of an introgression event","article_processing_charge":"Yes (via OA deal)","external_id":{"pmid":["30599087"],"isi":["000454600500001"]},"publist_id":"8014","author":[{"id":"4880FE40-F248-11E8-B48F-1D18A9856A87","first_name":"Nicholas H","last_name":"Barton","full_name":"Barton, Nicholas H","orcid":"0000-0002-8548-5240"}],"user_id":"c635000d-4b10-11ee-a964-aac5a93f6ac1","citation":{"ista":"Barton NH. 2018. The consequences of an introgression event. Molecular Ecology. 27(24), 4973–4975.","chicago":"Barton, Nicholas H. “The Consequences of an Introgression Event.” Molecular Ecology. Wiley, 2018. https://doi.org/10.1111/mec.14950.","short":"N.H. Barton, Molecular Ecology 27 (2018) 4973–4975.","ieee":"N. H. Barton, “The consequences of an introgression event,” Molecular Ecology, vol. 27, no. 24. Wiley, pp. 4973–4975, 2018.","apa":"Barton, N. H. (2018). The consequences of an introgression event. Molecular Ecology. Wiley. https://doi.org/10.1111/mec.14950","ama":"Barton NH. The consequences of an introgression event. Molecular Ecology. 2018;27(24):4973-4975. doi:10.1111/mec.14950","mla":"Barton, Nicholas H. “The Consequences of an Introgression Event.” Molecular Ecology, vol. 27, no. 24, Wiley, 2018, pp. 4973–75, doi:10.1111/mec.14950."}},{"month":"06","intvolume":" 7","scopus_import":"1","oa_version":"Published Version","abstract":[{"text":"In zebrafish larvae, it is the cell type that determines how the cell responds to a chemokine signal.","lang":"eng"}],"volume":7,"file":[{"date_created":"2019-02-13T10:52:11Z","file_name":"2018_eLife_Alanko.pdf","date_updated":"2020-07-14T12:47:13Z","file_size":358141,"creator":"dernst","checksum":"f1c7ec2a809408d763c4b529a98f9a3b","file_id":"5973","content_type":"application/pdf","access_level":"open_access","relation":"main_file"}],"language":[{"iso":"eng"}],"publication_identifier":{"issn":["2050084X"]},"publication_status":"published","status":"public","article_type":"original","type":"journal_article","tmp":{"legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode","image":"/images/cc_by.png","name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)","short":"CC BY (4.0)"},"_id":"5861","department":[{"_id":"MiSi"}],"file_date_updated":"2020-07-14T12:47:13Z","ddc":["570"],"date_updated":"2023-09-19T10:01:39Z","publisher":"eLife Sciences Publications","quality_controlled":"1","oa":1,"date_published":"2018-06-06T00:00:00Z","doi":"10.7554/eLife.37888","date_created":"2019-01-20T22:59:19Z","day":"06","publication":"eLife","isi":1,"has_accepted_license":"1","year":"2018","article_number":"e37888","title":"The cell sets the tone","author":[{"full_name":"Alanko, Jonna H","orcid":"0000-0002-7698-3061","last_name":"Alanko","first_name":"Jonna H","id":"2CC12E8C-F248-11E8-B48F-1D18A9856A87"},{"last_name":"Sixt","full_name":"Sixt, Michael K","orcid":"0000-0002-6620-9179","first_name":"Michael K","id":"41E9FBEA-F248-11E8-B48F-1D18A9856A87"}],"external_id":{"isi":["000434375000001"]},"article_processing_charge":"No","user_id":"c635000d-4b10-11ee-a964-aac5a93f6ac1","citation":{"chicago":"Alanko, Jonna H, and Michael K Sixt. “The Cell Sets the Tone.” ELife. eLife Sciences Publications, 2018. https://doi.org/10.7554/eLife.37888.","ista":"Alanko JH, Sixt MK. 2018. The cell sets the tone. eLife. 7, e37888.","mla":"Alanko, Jonna H., and Michael K. Sixt. “The Cell Sets the Tone.” ELife, vol. 7, e37888, eLife Sciences Publications, 2018, doi:10.7554/eLife.37888.","ieee":"J. H. Alanko and M. K. Sixt, “The cell sets the tone,” eLife, vol. 7. eLife Sciences Publications, 2018.","short":"J.H. Alanko, M.K. Sixt, ELife 7 (2018).","apa":"Alanko, J. H., & Sixt, M. K. (2018). The cell sets the tone. ELife. eLife Sciences Publications. https://doi.org/10.7554/eLife.37888","ama":"Alanko JH, Sixt MK. The cell sets the tone. eLife. 2018;7. doi:10.7554/eLife.37888"}},{"_id":"147","status":"public","article_type":"original","type":"journal_article","date_updated":"2023-09-19T10:09:12Z","department":[{"_id":"JiFr"}],"oa_version":"Published Version","pmid":1,"abstract":[{"text":"The trafficking of subcellular cargos in eukaryotic cells crucially depends on vesicle budding, a process mediated by ARF-GEFs (ADP-ribosylation factor guanine nucleotide exchange factors). In plants, ARF-GEFs play essential roles in endocytosis, vacuolar trafficking, recycling, secretion, and polar trafficking. Moreover, they are important for plant development, mainly through controlling the polar subcellular localization of PIN-FORMED (PIN) transporters of the plant hormone auxin. Here, using a chemical genetics screen in Arabidopsis thaliana, we identified Endosidin 4 (ES4), an inhibitor of eukaryotic ARF-GEFs. ES4 acts similarly to and synergistically with the established ARF-GEF inhibitor Brefeldin A and has broad effects on intracellular trafficking, including endocytosis, exocytosis, and vacuolar targeting. Additionally, Arabidopsis and yeast (Sacharomyces cerevisiae) mutants defective in ARF-GEF show altered sensitivity to ES4. ES4 interferes with the activation-based membrane association of the ARF1 GTPases, but not of their mutant variants that are activated independently of ARF-GEF activity. Biochemical approaches and docking simulations confirmed that ES4 specifically targets the SEC7 domain-containing ARF-GEFs. These observations collectively identify ES4 as a chemical tool enabling the study of ARF-GEF-mediated processes, including ARF-GEF-mediated plant development.","lang":"eng"}],"intvolume":" 30","month":"11","main_file_link":[{"open_access":"1","url":"https://doi.org/10.1105/tpc.18.00127"}],"scopus_import":"1","language":[{"iso":"eng"}],"publication_status":"published","publication_identifier":{"issn":["1040-4651"]},"ec_funded":1,"volume":30,"issue":"10","project":[{"name":"Polarity and subcellular dynamics in plants","grant_number":"282300","call_identifier":"FP7","_id":"25716A02-B435-11E9-9278-68D0E5697425"},{"_id":"261099A6-B435-11E9-9278-68D0E5697425","call_identifier":"H2020","name":"Tracing Evolution of Auxin Transport and Polarity in Plants","grant_number":"742985"}],"user_id":"c635000d-4b10-11ee-a964-aac5a93f6ac1","citation":{"ista":"Kania U, Nodzyński T, Lu Q, Hicks GR, Nerinckx W, Mishev K, Peurois F, Cherfils J, De RRM, Grones P, Robert S, Russinova E, Friml J. 2018. The inhibitor Endosidin 4 targets SEC7 domain-type ARF GTPase exchange factors and interferes with sub cellular trafficking in eukaryotes. The Plant Cell. 30(10), 2553–2572.","chicago":"Kania, Urszula, Tomasz Nodzyński, Qing Lu, Glenn R Hicks, Wim Nerinckx, Kiril Mishev, Francois Peurois, et al. “The Inhibitor Endosidin 4 Targets SEC7 Domain-Type ARF GTPase Exchange Factors and Interferes with Sub Cellular Trafficking in Eukaryotes.” The Plant Cell. Oxford University Press, 2018. https://doi.org/10.1105/tpc.18.00127.","ieee":"U. Kania et al., “The inhibitor Endosidin 4 targets SEC7 domain-type ARF GTPase exchange factors and interferes with sub cellular trafficking in eukaryotes,” The Plant Cell, vol. 30, no. 10. Oxford University Press, pp. 2553–2572, 2018.","short":"U. Kania, T. Nodzyński, Q. Lu, G.R. Hicks, W. Nerinckx, K. Mishev, F. Peurois, J. Cherfils, R.R.M. De, P. Grones, S. Robert, E. Russinova, J. Friml, The Plant Cell 30 (2018) 2553–2572.","ama":"Kania U, Nodzyński T, Lu Q, et al. The inhibitor Endosidin 4 targets SEC7 domain-type ARF GTPase exchange factors and interferes with sub cellular trafficking in eukaryotes. The Plant Cell. 2018;30(10):2553-2572. doi:10.1105/tpc.18.00127","apa":"Kania, U., Nodzyński, T., Lu, Q., Hicks, G. R., Nerinckx, W., Mishev, K., … Friml, J. (2018). The inhibitor Endosidin 4 targets SEC7 domain-type ARF GTPase exchange factors and interferes with sub cellular trafficking in eukaryotes. The Plant Cell. Oxford University Press. https://doi.org/10.1105/tpc.18.00127","mla":"Kania, Urszula, et al. “The Inhibitor Endosidin 4 Targets SEC7 Domain-Type ARF GTPase Exchange Factors and Interferes with Sub Cellular Trafficking in Eukaryotes.” The Plant Cell, vol. 30, no. 10, Oxford University Press, 2018, pp. 2553–72, doi:10.1105/tpc.18.00127."},"title":"The inhibitor Endosidin 4 targets SEC7 domain-type ARF GTPase exchange factors and interferes with sub cellular trafficking in eukaryotes","external_id":{"isi":["000450000500023"],"pmid":["30018156"]},"article_processing_charge":"No","publist_id":"7776","author":[{"full_name":"Kania, Urszula","last_name":"Kania","first_name":"Urszula","id":"4AE5C486-F248-11E8-B48F-1D18A9856A87"},{"last_name":"Nodzyński","full_name":"Nodzyński, Tomasz","first_name":"Tomasz"},{"first_name":"Qing","last_name":"Lu","full_name":"Lu, Qing"},{"full_name":"Hicks, Glenn R","last_name":"Hicks","first_name":"Glenn R"},{"last_name":"Nerinckx","full_name":"Nerinckx, Wim","first_name":"Wim"},{"last_name":"Mishev","full_name":"Mishev, Kiril","first_name":"Kiril"},{"full_name":"Peurois, Francois","last_name":"Peurois","first_name":"Francois"},{"full_name":"Cherfils, Jacqueline","last_name":"Cherfils","first_name":"Jacqueline"},{"first_name":"Rycke Riet Maria","full_name":"De, Rycke Riet Maria","last_name":"De"},{"last_name":"Grones","full_name":"Grones, Peter","id":"399876EC-F248-11E8-B48F-1D18A9856A87","first_name":"Peter"},{"first_name":"Stéphanie","last_name":"Robert","full_name":"Robert, Stéphanie"},{"last_name":"Russinova","full_name":"Russinova, Eugenia","first_name":"Eugenia"},{"last_name":"Friml","orcid":"0000-0002-8302-7596","full_name":"Friml, Jirí","first_name":"Jirí","id":"4159519E-F248-11E8-B48F-1D18A9856A87"}],"acknowledgement":"We thank Gerd Jürgens, Sandra Richter, and Sheng Yang He for providing antibodies; Maciek Adamowski, Fernando Aniento, Sebastian Bednarek, Nico Callewaert, Matyás Fendrych, Elena Feraru, and Mugurel I. Feraru for helpful suggestions; Siamsa Doyle for critical reading of the manuscript and helpful comments and suggestions; and Stephanie Smith and Martine De Cock for help in editing and language corrections. We acknowledge the core facility Cellular Imaging of CEITEC supported by the Czech-BioImaging large RI project (LM2015062 funded by MEYS CR) for their support with obtaining scientific data presented in this article. Plant Sciences Core Facility of CEITEC Masaryk University is gratefully acknowledged for obtaining part of the scientific data presented in this article. We acknowledge support from the Fondation pour la Recherche Médicale and from the Institut National du Cancer (J.C.). The research leading to these results was funded by the European Research Council under the European Union's 7th Framework Program (FP7/2007-2013)/ERC grant agreement numbers 282300 and 742985 and the Czech Science Foundation GAČR (GA18-26981S; J.F.); Ministry of Education, Youth, and Sports/MEYS of the Czech Republic under the Project CEITEC 2020 (LQ1601; T.N.); the China Science Council for a predoctoral fellowship (Q.L.); a joint research project within the framework of cooperation between the Research Foundation-Flanders and the Bulgarian Academy of Sciences (VS.025.13N; K.M. and E.R.); Vetenskapsrådet and Vinnova (Verket för Innovationssystem; S.R.), Knut och Alice Wallenbergs Stiftelse via “Shapesystem” Grant 2012.0050 (S.R.), Kempe stiftelserna (P.G.), Tryggers CTS410 (P.G.).","oa":1,"quality_controlled":"1","publisher":"Oxford University Press","publication":"The Plant Cell","day":"12","year":"2018","isi":1,"date_created":"2018-12-11T11:44:52Z","date_published":"2018-11-12T00:00:00Z","doi":"10.1105/tpc.18.00127","page":"2553 - 2572"},{"title":"The dynamics of root cap sloughing in Arabidopsis is regulated by peptide signalling","external_id":{"isi":["000443861300016"],"pmid":["30061750"]},"article_processing_charge":"No","author":[{"last_name":"Shi","full_name":"Shi, Chun Lin","first_name":"Chun Lin"},{"last_name":"Von Wangenheim","full_name":"Von Wangenheim, Daniel","orcid":"0000-0002-6862-1247","first_name":"Daniel","id":"49E91952-F248-11E8-B48F-1D18A9856A87"},{"first_name":"Ullrich","last_name":"Herrmann","full_name":"Herrmann, Ullrich"},{"last_name":"Wildhagen","full_name":"Wildhagen, Mari","first_name":"Mari"},{"full_name":"Kulik, Ivan","last_name":"Kulik","first_name":"Ivan","id":"F0AB3FCE-02D1-11E9-BD0E-99399A5D3DEB"},{"last_name":"Kopf","full_name":"Kopf, Andreas","first_name":"Andreas"},{"first_name":"Takashi","last_name":"Ishida","full_name":"Ishida, Takashi"},{"first_name":"Vilde","last_name":"Olsson","full_name":"Olsson, Vilde"},{"full_name":"Anker, Mari Kristine","last_name":"Anker","first_name":"Mari Kristine"},{"full_name":"Albert, Markus","last_name":"Albert","first_name":"Markus"},{"first_name":"Melinka A","last_name":"Butenko","full_name":"Butenko, Melinka A"},{"last_name":"Felix","full_name":"Felix, Georg","first_name":"Georg"},{"first_name":"Shinichiro","last_name":"Sawa","full_name":"Sawa, Shinichiro"},{"first_name":"Manfred","last_name":"Claassen","full_name":"Claassen, Manfred"},{"first_name":"Jirí","id":"4159519E-F248-11E8-B48F-1D18A9856A87","orcid":"0000-0002-8302-7596","full_name":"Friml, Jirí","last_name":"Friml"},{"first_name":"Reidunn B","last_name":"Aalen","full_name":"Aalen, Reidunn B"}],"publist_id":"7777","user_id":"c635000d-4b10-11ee-a964-aac5a93f6ac1","citation":{"apa":"Shi, C. L., von Wangenheim, D., Herrmann, U., Wildhagen, M., Kulik, I., Kopf, A., … Aalen, R. B. (2018). The dynamics of root cap sloughing in Arabidopsis is regulated by peptide signalling. Nature Plants. Nature Publishing Group. https://doi.org/10.1038/s41477-018-0212-z","ama":"Shi CL, von Wangenheim D, Herrmann U, et al. The dynamics of root cap sloughing in Arabidopsis is regulated by peptide signalling. Nature Plants. 2018;4(8):596-604. doi:10.1038/s41477-018-0212-z","short":"C.L. Shi, D. von Wangenheim, U. Herrmann, M. Wildhagen, I. Kulik, A. Kopf, T. Ishida, V. Olsson, M.K. Anker, M. Albert, M.A. Butenko, G. Felix, S. Sawa, M. Claassen, J. Friml, R.B. Aalen, Nature Plants 4 (2018) 596–604.","ieee":"C. L. Shi et al., “The dynamics of root cap sloughing in Arabidopsis is regulated by peptide signalling,” Nature Plants, vol. 4, no. 8. Nature Publishing Group, pp. 596–604, 2018.","mla":"Shi, Chun Lin, et al. “The Dynamics of Root Cap Sloughing in Arabidopsis Is Regulated by Peptide Signalling.” Nature Plants, vol. 4, no. 8, Nature Publishing Group, 2018, pp. 596–604, doi:10.1038/s41477-018-0212-z.","ista":"Shi CL, von Wangenheim D, Herrmann U, Wildhagen M, Kulik I, Kopf A, Ishida T, Olsson V, Anker MK, Albert M, Butenko MA, Felix G, Sawa S, Claassen M, Friml J, Aalen RB. 2018. The dynamics of root cap sloughing in Arabidopsis is regulated by peptide signalling. Nature Plants. 4(8), 596–604.","chicago":"Shi, Chun Lin, Daniel von Wangenheim, Ullrich Herrmann, Mari Wildhagen, Ivan Kulik, Andreas Kopf, Takashi Ishida, et al. “The Dynamics of Root Cap Sloughing in Arabidopsis Is Regulated by Peptide Signalling.” Nature Plants. Nature Publishing Group, 2018. https://doi.org/10.1038/s41477-018-0212-z."},"date_created":"2018-12-11T11:44:52Z","date_published":"2018-07-30T00:00:00Z","doi":"10.1038/s41477-018-0212-z","page":"596 - 604","publication":"Nature Plants","day":"30","year":"2018","has_accepted_license":"1","isi":1,"oa":1,"quality_controlled":"1","publisher":"Nature Publishing Group","file_date_updated":"2020-07-14T12:44:56Z","department":[{"_id":"JiFr"}],"ddc":["580"],"date_updated":"2023-09-19T10:08:45Z","status":"public","type":"journal_article","article_type":"original","_id":"146","volume":4,"issue":"8","related_material":{"link":[{"url":"https://ist.ac.at/en/news/new-process-in-root-development-discovered/","relation":"press_release","description":"News on IST Homepage"}]},"language":[{"iso":"eng"}],"file":[{"file_name":"2018_NaturePlants_Shi.pdf","date_created":"2019-11-18T16:24:07Z","file_size":226829,"date_updated":"2020-07-14T12:44:56Z","creator":"dernst","checksum":"da33101c76ee1b2dc5ab28fd2ccba9d0","file_id":"7043","content_type":"application/pdf","relation":"main_file","access_level":"open_access"}],"publication_status":"published","intvolume":" 4","month":"07","scopus_import":"1","oa_version":"Submitted Version","pmid":1,"abstract":[{"text":"The root cap protects the stem cell niche of angiosperm roots from damage. In Arabidopsis, lateral root cap (LRC) cells covering the meristematic zone are regularly lost through programmed cell death, while the outermost layer of the root cap covering the tip is repeatedly sloughed. Efficient coordination with stem cells producing new layers is needed to maintain a constant size of the cap. We present a signalling pair, the peptide IDA-LIKE1 (IDL1) and its receptor HAESA-LIKE2 (HSL2), mediating such communication. Live imaging over several days characterized this process from initial fractures in LRC cell files to full separation of a layer. Enhanced expression of IDL1 in the separating root cap layers resulted in increased frequency of sloughing, balanced with generation of new layers in a HSL2-dependent manner. Transcriptome analyses linked IDL1-HSL2 signalling to the transcription factors BEARSKIN1/2 and genes associated with programmed cell death. Mutations in either IDL1 or HSL2 slowed down cell division, maturation and separation. Thus, IDL1-HSL2 signalling potentiates dynamic regulation of the homeostatic balance between stem cell division and sloughing activity.","lang":"eng"}]},{"date_updated":"2023-09-19T10:12:03Z","ddc":["000"],"department":[{"_id":"KrCh"}],"file_date_updated":"2020-07-14T12:45:54Z","_id":"293","type":"journal_article","article_type":"original","status":"public","publication_status":"published","language":[{"iso":"eng"}],"file":[{"file_name":"2018_NatureHumanBeh_Hoffman.pdf","date_created":"2019-11-19T08:17:23Z","creator":"dernst","file_size":194734,"date_updated":"2020-07-14T12:45:54Z","checksum":"32efaf06a597495c184df91b3fbb19c0","file_id":"7051","relation":"main_file","access_level":"open_access","content_type":"application/pdf"}],"ec_funded":1,"volume":2,"related_material":{"link":[{"relation":"press_release","url":"https://ist.ac.at/en/news/the-logic-of-modesty-why-it-pays-to-be-humble/","description":"News on IST Homepage"}]},"abstract":[{"lang":"eng","text":"People sometimes make their admirable deeds and accomplishments hard to spot, such as by giving anonymously or avoiding bragging. Such ‘buried’ signals are hard to reconcile with standard models of signalling or indirect reciprocity, which motivate costly pro-social behaviour by reputational gains. To explain these phenomena, we design a simple game theory model, which we call the signal-burying game. This game has the feature that senders can bury their signal by deliberately reducing the probability of the signal being observed. If the signal is observed, however, it is identified as having been buried. We show under which conditions buried signals can be maintained, using static equilibrium concepts and calculations of the evolutionary dynamics. We apply our analysis to shed light on a number of otherwise puzzling social phenomena, including modesty, anonymous donations, subtlety in art and fashion, and overeagerness."}],"oa_version":"Submitted Version","scopus_import":"1","intvolume":" 2","month":"05","citation":{"mla":"Hoffman, Moshe, et al. “The Signal-Burying Game Can Explain Why We Obscure Positive Traits and Good Deeds.” Nature Human Behaviour, vol. 2, Nature Publishing Group, 2018, pp. 397–404, doi:10.1038/s41562-018-0354-z.","ama":"Hoffman M, Hilbe C, Nowak M. The signal-burying game can explain why we obscure positive traits and good deeds. Nature Human Behaviour. 2018;2:397-404. doi:10.1038/s41562-018-0354-z","apa":"Hoffman, M., Hilbe, C., & Nowak, M. (2018). The signal-burying game can explain why we obscure positive traits and good deeds. Nature Human Behaviour. Nature Publishing Group. https://doi.org/10.1038/s41562-018-0354-z","ieee":"M. Hoffman, C. Hilbe, and M. Nowak, “The signal-burying game can explain why we obscure positive traits and good deeds,” Nature Human Behaviour, vol. 2. Nature Publishing Group, pp. 397–404, 2018.","short":"M. Hoffman, C. Hilbe, M. Nowak, Nature Human Behaviour 2 (2018) 397–404.","chicago":"Hoffman, Moshe, Christian Hilbe, and Martin Nowak. “The Signal-Burying Game Can Explain Why We Obscure Positive Traits and Good Deeds.” Nature Human Behaviour. Nature Publishing Group, 2018. https://doi.org/10.1038/s41562-018-0354-z.","ista":"Hoffman M, Hilbe C, Nowak M. 2018. The signal-burying game can explain why we obscure positive traits and good deeds. 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C.H. acknowledges generous support from the ISTFELLOW programme and by the Schrödinger scholarship of the Austrian Science Fund (FWF) J3475.","oa":1,"publisher":"Nature Publishing Group","quality_controlled":"1"},{"oa":1,"quality_controlled":"1","publisher":"Birkhäuser","acknowledgement":"Open access funding provided by Institute of Science and Technology (IST Austria). The authors acknowledge support by ERC Advanced Grant 321029 and by VILLUM FONDEN via the QMATH Centre of Excellence (Grant No. 10059). The authors would like to thank Sébastien Breteaux, Enno Lenzmann, Mathieu Lewin and Jochen Schmid for comments and discussions about well-posedness of the Bogoliubov–de Gennes equations.","page":"1167 - 1214","date_created":"2018-12-11T11:46:34Z","doi":"10.1007/s00023-018-0644-z","date_published":"2018-04-01T00:00:00Z","year":"2018","isi":1,"has_accepted_license":"1","publication":"Annales Henri Poincare","day":"01","article_processing_charge":"No","external_id":{"isi":["000427578900006"]},"author":[{"full_name":"Benedikter, Niels P","orcid":"0000-0002-1071-6091","last_name":"Benedikter","id":"3DE6C32A-F248-11E8-B48F-1D18A9856A87","first_name":"Niels P"},{"first_name":"Jérémy","last_name":"Sok","full_name":"Sok, Jérémy"},{"last_name":"Solovej","full_name":"Solovej, Jan","first_name":"Jan"}],"publist_id":"7367","title":"The Dirac–Frenkel principle for reduced density matrices and the Bogoliubov–de Gennes equations","citation":{"ista":"Benedikter NP, Sok J, Solovej J. 2018. The Dirac–Frenkel principle for reduced density matrices and the Bogoliubov–de Gennes equations. Annales Henri Poincare. 19(4), 1167–1214.","chicago":"Benedikter, Niels P, Jérémy Sok, and Jan Solovej. “The Dirac–Frenkel Principle for Reduced Density Matrices and the Bogoliubov–de Gennes Equations.” Annales Henri Poincare. Birkhäuser, 2018. https://doi.org/10.1007/s00023-018-0644-z.","apa":"Benedikter, N. P., Sok, J., & Solovej, J. (2018). The Dirac–Frenkel principle for reduced density matrices and the Bogoliubov–de Gennes equations. Annales Henri Poincare. Birkhäuser. https://doi.org/10.1007/s00023-018-0644-z","ama":"Benedikter NP, Sok J, Solovej J. The Dirac–Frenkel principle for reduced density matrices and the Bogoliubov–de Gennes equations. Annales Henri Poincare. 2018;19(4):1167-1214. doi:10.1007/s00023-018-0644-z","ieee":"N. P. Benedikter, J. Sok, and J. Solovej, “The Dirac–Frenkel principle for reduced density matrices and the Bogoliubov–de Gennes equations,” Annales Henri Poincare, vol. 19, no. 4. Birkhäuser, pp. 1167–1214, 2018.","short":"N.P. Benedikter, J. Sok, J. Solovej, Annales Henri Poincare 19 (2018) 1167–1214.","mla":"Benedikter, Niels P., et al. “The Dirac–Frenkel Principle for Reduced Density Matrices and the Bogoliubov–de Gennes Equations.” Annales Henri Poincare, vol. 19, no. 4, Birkhäuser, 2018, pp. 1167–214, doi:10.1007/s00023-018-0644-z."},"user_id":"c635000d-4b10-11ee-a964-aac5a93f6ac1","alternative_title":["Annales Henri Poincare"],"scopus_import":"1","intvolume":" 19","month":"04","abstract":[{"lang":"eng","text":"The derivation of effective evolution equations is central to the study of non-stationary quantum many-body systems, and widely used in contexts such as superconductivity, nuclear physics, Bose–Einstein condensation and quantum chemistry. We reformulate the Dirac–Frenkel approximation principle in terms of reduced density matrices and apply it to fermionic and bosonic many-body systems. We obtain the Bogoliubov–de Gennes and Hartree–Fock–Bogoliubov equations, respectively. While we do not prove quantitative error estimates, our formulation does show that the approximation is optimal within the class of quasifree states. Furthermore, we prove well-posedness of the Bogoliubov–de Gennes equations in energy space and discuss conserved quantities"}],"oa_version":"Published Version","volume":19,"issue":"4","publication_status":"published","language":[{"iso":"eng"}],"file":[{"file_name":"IST-2018-993-v1+1_2018_Benedikter_Dirac.pdf","date_created":"2018-12-12T10:11:57Z","file_size":923252,"date_updated":"2020-07-14T12:46:31Z","creator":"system","file_id":"4914","checksum":"883eeccba8384ad7fcaa28761d99a0fa","content_type":"application/pdf","relation":"main_file","access_level":"open_access"}],"tmp":{"legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode","image":"/images/cc_by.png","name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)","short":"CC BY (4.0)"},"type":"journal_article","pubrep_id":"993","status":"public","_id":"455","department":[{"_id":"RoSe"}],"file_date_updated":"2020-07-14T12:46:31Z","date_updated":"2023-09-19T10:07:41Z","ddc":["510","539"]},{"article_processing_charge":"No","external_id":{"isi":["000432192100003"],"pmid":["29698645"]},"author":[{"first_name":"Guntram","full_name":"Bauer, Guntram","last_name":"Bauer"},{"first_name":"Nikta","last_name":"Fakhri","full_name":"Fakhri, Nikta"},{"first_name":"Anna","id":"3959A2A0-F248-11E8-B48F-1D18A9856A87","last_name":"Kicheva","full_name":"Kicheva, Anna","orcid":"0000-0003-4509-4998"},{"full_name":"Kondev, Jané","last_name":"Kondev","first_name":"Jané"},{"full_name":"Kruse, Karsten","last_name":"Kruse","first_name":"Karsten"},{"first_name":"Hiroyuki","full_name":"Noji, Hiroyuki","last_name":"Noji"},{"first_name":"Daniel","full_name":"Riveline, Daniel","last_name":"Riveline"},{"last_name":"Saunders","full_name":"Saunders, Timothy","first_name":"Timothy"},{"first_name":"Mukund","full_name":"Thatta, Mukund","last_name":"Thatta"},{"first_name":"Eric","full_name":"Wieschaus, Eric","last_name":"Wieschaus"}],"publist_id":"7551","title":"The science of living matter for tomorrow","citation":{"ista":"Bauer G, Fakhri N, Kicheva A, Kondev J, Kruse K, Noji H, Riveline D, Saunders T, Thatta M, Wieschaus E. 2018. The science of living matter for tomorrow. Cell Systems. 6(4), 400–402.","chicago":"Bauer, Guntram, Nikta Fakhri, Anna Kicheva, Jané Kondev, Karsten Kruse, Hiroyuki Noji, Daniel Riveline, Timothy Saunders, Mukund Thatta, and Eric Wieschaus. “The Science of Living Matter for Tomorrow.” Cell Systems. Cell Press, 2018. https://doi.org/10.1016/j.cels.2018.04.003.","ama":"Bauer G, Fakhri N, Kicheva A, et al. The science of living matter for tomorrow. Cell Systems. 2018;6(4):400-402. doi:10.1016/j.cels.2018.04.003","apa":"Bauer, G., Fakhri, N., Kicheva, A., Kondev, J., Kruse, K., Noji, H., … Wieschaus, E. (2018). The science of living matter for tomorrow. Cell Systems. Cell Press. https://doi.org/10.1016/j.cels.2018.04.003","short":"G. Bauer, N. Fakhri, A. Kicheva, J. Kondev, K. Kruse, H. Noji, D. Riveline, T. Saunders, M. Thatta, E. Wieschaus, Cell Systems 6 (2018) 400–402.","ieee":"G. Bauer et al., “The science of living matter for tomorrow,” Cell Systems, vol. 6, no. 4. Cell Press, pp. 400–402, 2018.","mla":"Bauer, Guntram, et al. “The Science of Living Matter for Tomorrow.” Cell Systems, vol. 6, no. 4, Cell Press, 2018, pp. 400–02, doi:10.1016/j.cels.2018.04.003."},"user_id":"c635000d-4b10-11ee-a964-aac5a93f6ac1","oa":1,"publisher":"Cell Press","quality_controlled":"1","page":"400 - 402","date_created":"2018-12-11T11:45:46Z","date_published":"2018-04-25T00:00:00Z","doi":"10.1016/j.cels.2018.04.003","year":"2018","isi":1,"publication":"Cell Systems","day":"25","type":"journal_article","article_type":"letter_note","status":"public","_id":"314","department":[{"_id":"AnKi"}],"date_updated":"2023-09-19T10:11:25Z","main_file_link":[{"url":"https://doi.org/10.1016/j.cels.2018.04.003","open_access":"1"}],"scopus_import":"1","intvolume":" 6","month":"04","abstract":[{"lang":"eng","text":"The interface of physics and biology pro-vides a fruitful environment for generatingnew concepts and exciting ways forwardto understanding living matter. Examplesof successful studies include the estab-lishment and readout of morphogen gra-dients during development, signal pro-cessing in protein and genetic networks,the role of fluctuations in determining thefates of cells and tissues, and collectiveeffects in proteins and in tissues. It is nothard to envision that significant further ad-vances will translate to societal benefitsby initiating the development of new de-vices and strategies for curing disease.However, research at the interface posesvarious challenges, in particular for youngscientists, and current institutions arerarely designed to facilitate such scientificprograms. In this Letter, we propose aninternational initiative that addressesthese challenges through the establish-ment of a worldwide network of platformsfor cross-disciplinary training and incuba-tors for starting new collaborations."}],"pmid":1,"oa_version":"Published Version","issue":"4","volume":6,"publication_status":"published","publication_identifier":{"eissn":["2405-4712"]},"language":[{"iso":"eng"}]},{"user_id":"c635000d-4b10-11ee-a964-aac5a93f6ac1","citation":{"ista":"Charlesworth B, Barton NH. 2018. The spread of an inversion with migration and selection. Genetics. 208(1), 377–382.","chicago":"Charlesworth, Brian, and Nicholas H Barton. “The Spread of an Inversion with Migration and Selection.” Genetics. Genetics , 2018. https://doi.org/10.1534/genetics.117.300426.","ieee":"B. Charlesworth and N. H. Barton, “The spread of an inversion with migration and selection,” Genetics, vol. 208, no. 1. Genetics , pp. 377–382, 2018.","short":"B. Charlesworth, N.H. Barton, Genetics 208 (2018) 377–382.","ama":"Charlesworth B, Barton NH. The spread of an inversion with migration and selection. Genetics. 2018;208(1):377-382. doi:10.1534/genetics.117.300426","apa":"Charlesworth, B., & Barton, N. H. (2018). The spread of an inversion with migration and selection. Genetics. Genetics . https://doi.org/10.1534/genetics.117.300426","mla":"Charlesworth, Brian, and Nicholas H. Barton. “The Spread of an Inversion with Migration and Selection.” Genetics, vol. 208, no. 1, Genetics , 2018, pp. 377–82, doi:10.1534/genetics.117.300426."},"title":"The spread of an inversion with migration and selection","publist_id":"7249","author":[{"first_name":"Brian","full_name":"Charlesworth, Brian","last_name":"Charlesworth"},{"id":"4880FE40-F248-11E8-B48F-1D18A9856A87","first_name":"Nicholas H","orcid":"0000-0002-8548-5240","full_name":"Barton, Nicholas H","last_name":"Barton"}],"article_processing_charge":"No","external_id":{"isi":["000419356300025"],"pmid":["29158424"]},"day":"01","publication":"Genetics","isi":1,"year":"2018","doi":"10.1534/genetics.117.300426","date_published":"2018-01-01T00:00:00Z","date_created":"2018-12-11T11:47:12Z","page":"377 - 382","publisher":"Genetics ","quality_controlled":"1","oa":1,"date_updated":"2023-09-19T10:12:31Z","department":[{"_id":"NiBa"}],"_id":"565","status":"public","article_type":"original","type":"journal_article","language":[{"iso":"eng"}],"publication_status":"published","issue":"1","volume":208,"oa_version":"Published Version","pmid":1,"abstract":[{"text":"We re-examine the model of Kirkpatrick and Barton for the spread of an inversion into a local population. This model assumes that local selection maintains alleles at two or more loci, despite immigration of alternative alleles at these loci from another population. We show that an inversion is favored because it prevents the breakdown of linkage disequilibrium generated by migration; the selective advantage of an inversion is proportional to the amount of recombination between the loci involved, as in other cases where inversions are selected for. We derive expressions for the rate of spread of an inversion; when the loci covered by the inversion are tightly linked, these conditions deviate substantially from those proposed previously, and imply that an inversion can then have only a small advantage. ","lang":"eng"}],"month":"01","intvolume":" 208","scopus_import":"1","main_file_link":[{"url":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5753870/","open_access":"1"}]},{"intvolume":" 71","month":"03","main_file_link":[{"open_access":"1","url":"https://arxiv.org/abs/1606.07355"}],"oa_version":"Preprint","abstract":[{"text":"We prove that in Thomas–Fermi–Dirac–von Weizsäcker theory, a nucleus of charge Z > 0 can bind at most Z + C electrons, where C is a universal constant. This result is obtained through a comparison with Thomas-Fermi theory which, as a by-product, gives bounds on the screened nuclear potential and the radius of the minimizer. A key ingredient of the proof is a novel technique to control the particles in the exterior region, which also applies to the liquid drop model with a nuclear background potential.","lang":"eng"}],"issue":"3","volume":71,"language":[{"iso":"eng"}],"publication_status":"published","status":"public","type":"journal_article","article_type":"original","_id":"446","department":[{"_id":"RoSe"}],"date_updated":"2023-09-19T10:09:40Z","oa":1,"publisher":"Wiley-Blackwell","quality_controlled":"1","acknowledgement":"We thank the referee for helpful suggestions that improved the presentation of the paper. We also acknowledge partial support by National Science Foundation Grant DMS-1363432 (R.L.F.), Austrian Science Fund (FWF) Project Nr. P 27533-N27 (P.T.N.), CONICYT (Chile) through CONICYT–PCHA/ Doctorado Nacional/2014, and Iniciativa Científica Milenio (Chile) through Millenium Nucleus RC–120002 “Física Matemática” (H.V.D.B.).\r\n","date_created":"2018-12-11T11:46:31Z","date_published":"2018-03-01T00:00:00Z","doi":"10.1002/cpa.21717","page":"577 - 614","publication":"Communications on Pure and Applied Mathematics","day":"01","year":"2018","isi":1,"title":"The ionization conjecture in Thomas–Fermi–Dirac–von Weizsäcker theory","article_processing_charge":"No","external_id":{"arxiv":["1606.07355"],"isi":["000422675800004"]},"author":[{"first_name":"Rupert","last_name":"Frank","full_name":"Frank, Rupert"},{"last_name":"Phan Thanh","full_name":"Phan Thanh, Nam","first_name":"Nam","id":"404092F4-F248-11E8-B48F-1D18A9856A87"},{"first_name":"Hanne","last_name":"Van Den Bosch","full_name":"Van Den Bosch, Hanne"}],"publist_id":"7377","user_id":"c635000d-4b10-11ee-a964-aac5a93f6ac1","citation":{"short":"R. Frank, P. Nam, H. Van Den Bosch, Communications on Pure and Applied Mathematics 71 (2018) 577–614.","ieee":"R. Frank, P. Nam, and H. Van Den Bosch, “The ionization conjecture in Thomas–Fermi–Dirac–von Weizsäcker theory,” Communications on Pure and Applied Mathematics, vol. 71, no. 3. Wiley-Blackwell, pp. 577–614, 2018.","ama":"Frank R, Nam P, Van Den Bosch H. The ionization conjecture in Thomas–Fermi–Dirac–von Weizsäcker theory. Communications on Pure and Applied Mathematics. 2018;71(3):577-614. doi:10.1002/cpa.21717","apa":"Frank, R., Nam, P., & Van Den Bosch, H. (2018). The ionization conjecture in Thomas–Fermi–Dirac–von Weizsäcker theory. Communications on Pure and Applied Mathematics. Wiley-Blackwell. https://doi.org/10.1002/cpa.21717","mla":"Frank, Rupert, et al. “The Ionization Conjecture in Thomas–Fermi–Dirac–von Weizsäcker Theory.” Communications on Pure and Applied Mathematics, vol. 71, no. 3, Wiley-Blackwell, 2018, pp. 577–614, doi:10.1002/cpa.21717.","ista":"Frank R, Nam P, Van Den Bosch H. 2018. The ionization conjecture in Thomas–Fermi–Dirac–von Weizsäcker theory. Communications on Pure and Applied Mathematics. 71(3), 577–614.","chicago":"Frank, Rupert, Phan Nam, and Hanne Van Den Bosch. “The Ionization Conjecture in Thomas–Fermi–Dirac–von Weizsäcker Theory.” Communications on Pure and Applied Mathematics. Wiley-Blackwell, 2018. https://doi.org/10.1002/cpa.21717."}},{"title":"Tread lightly interpreting polygenic tests of selection","author":[{"last_name":"Novembre","full_name":"Novembre, John","first_name":"John"},{"id":"4880FE40-F248-11E8-B48F-1D18A9856A87","first_name":"Nicholas H","orcid":"0000-0002-8548-5240","full_name":"Barton, Nicholas H","last_name":"Barton"}],"publist_id":"7393","external_id":{"isi":["000429094400005"]},"article_processing_charge":"No","user_id":"c635000d-4b10-11ee-a964-aac5a93f6ac1","citation":{"mla":"Novembre, John, and Nicholas H. Barton. “Tread Lightly Interpreting Polygenic Tests of Selection.” Genetics, vol. 208, no. 4, Genetics Society of America, 2018, pp. 1351–55, doi:10.1534/genetics.118.300786.","ama":"Novembre J, Barton NH. Tread lightly interpreting polygenic tests of selection. Genetics. 2018;208(4):1351-1355. doi:10.1534/genetics.118.300786","apa":"Novembre, J., & Barton, N. H. (2018). Tread lightly interpreting polygenic tests of selection. Genetics. Genetics Society of America. https://doi.org/10.1534/genetics.118.300786","short":"J. Novembre, N.H. Barton, Genetics 208 (2018) 1351–1355.","ieee":"J. Novembre and N. H. Barton, “Tread lightly interpreting polygenic tests of selection,” Genetics, vol. 208, no. 4. Genetics Society of America, pp. 1351–1355, 2018.","chicago":"Novembre, John, and Nicholas H Barton. “Tread Lightly Interpreting Polygenic Tests of Selection.” Genetics. Genetics Society of America, 2018. https://doi.org/10.1534/genetics.118.300786.","ista":"Novembre J, Barton NH. 2018. Tread lightly interpreting polygenic tests of selection. Genetics. 208(4), 1351–1355."},"doi":"10.1534/genetics.118.300786","date_published":"2018-04-01T00:00:00Z","date_created":"2018-12-11T11:46:26Z","page":"1351 - 1355","day":"01","publication":"Genetics","has_accepted_license":"1","isi":1,"year":"2018","quality_controlled":"1","publisher":"Genetics Society of America","oa":1,"file_date_updated":"2020-07-14T12:46:26Z","department":[{"_id":"NiBa"}],"ddc":["576"],"date_updated":"2023-09-19T10:17:30Z","status":"public","pubrep_id":"1012","type":"journal_article","tmp":{"legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode","image":"/images/cc_by.png","name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)","short":"CC BY (4.0)"},"_id":"430","issue":"4","volume":208,"file":[{"file_name":"IST-2018-1012-v1+1_2018_Barton_Tread.pdf","date_created":"2018-12-12T10:12:40Z","file_size":500129,"date_updated":"2020-07-14T12:46:26Z","creator":"system","file_id":"4958","checksum":"3d838dc285df394376555b794b6a5ad1","content_type":"application/pdf","relation":"main_file","access_level":"open_access"}],"language":[{"iso":"eng"}],"publication_status":"published","month":"04","intvolume":" 208","scopus_import":"1","oa_version":"Published Version","abstract":[{"text":"In this issue of GENETICS, a new method for detecting natural selection on polygenic traits is developed and applied to sev- eral human examples ( Racimo et al. 2018 ). By de fi nition, many loci contribute to variation in polygenic traits, and a challenge for evolutionary ge neticists has been that these traits can evolve by small, nearly undetectable shifts in allele frequencies across each of many, typically unknown, loci. Recently, a helpful remedy has arisen. Genome-wide associ- ation studies (GWAS) have been illuminating sets of loci that can be interrogated jointly for c hanges in allele frequencies. By aggregating small signal s of change across many such loci, directional natural selection is now in principle detect- able using genetic data, even for highly polygenic traits. This is an exciting arena of progress – with these methods, tests can be made for selection associated with traits, and we can now study selection in what may be its most prevalent mode. The continuing fast pace of GWAS publications suggest there will be many more polygenic tests of selection in the near future, as every new GWAS is an opportunity for an accom- panying test of polygenic selection. However, it is important to be aware of complications th at arise in interpretation, especially given that these studies may easily be misinter- preted both in and outside the evolutionary genetics commu- nity. Here, we provide context for understanding polygenic tests and urge caution regarding how these results are inter- preted and reported upon more broadly.","lang":"eng"}]},{"department":[{"_id":"BeVi"}],"file_date_updated":"2020-07-14T12:45:22Z","date_updated":"2023-09-19T10:15:31Z","ddc":["570"],"tmp":{"legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode","image":"/images/cc_by.png","name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)","short":"CC BY (4.0)"},"type":"journal_article","status":"public","_id":"199","issue":"6","volume":9,"publication_status":"published","language":[{"iso":"eng"}],"file":[{"file_size":3985796,"date_updated":"2020-07-14T12:45:22Z","creator":"dernst","file_name":"2018_Genes_Ma.pdf","date_created":"2019-02-01T07:52:28Z","content_type":"application/pdf","relation":"main_file","access_level":"open_access","file_id":"5905","checksum":"423069beb1cd3cdd25bf3f464b38f1d7"}],"scopus_import":"1","intvolume":" 9","month":"06","abstract":[{"lang":"eng","text":"Sex-biased genes are central to the study of sexual selection, sexual antagonism, and sex chromosome evolution. We describe a comprehensive de novo assembled transcriptome in the common frog Rana temporaria based on five developmental stages and three adult tissues from both sexes, obtained from a population with karyotypically homomorphic but genetically differentiated sex chromosomes. This allows the study of sex-biased gene expression throughout development, and its effect on the rate of gene evolution while accounting for pleiotropic expression, which is known to negatively correlate with the evolutionary rate. Overall, sex-biased genes had little overlap among developmental stages and adult tissues. Late developmental stages and gonad tissues had the highest numbers of stage-or tissue-specific genes. We find that pleiotropic gene expression is a better predictor than sex bias for the evolutionary rate of genes, though it often interacts with sex bias. Although genetically differentiated, the sex chromosomes were not enriched in sex-biased genes, possibly due to a very recent arrest of XY recombination. These results extend our understanding of the developmental dynamics, tissue specificity, and genomic localization of sex-biased genes."}],"oa_version":"Published Version","article_processing_charge":"No","external_id":{"isi":["000436494200026"]},"author":[{"last_name":"Ma","full_name":"Ma, Wen","first_name":"Wen"},{"first_name":"Paris","last_name":"Veltsos","full_name":"Veltsos, Paris"},{"id":"4E099E4E-F248-11E8-B48F-1D18A9856A87","first_name":"Melissa A","orcid":"0000-0002-9752-7380","full_name":"Toups, Melissa A","last_name":"Toups"},{"first_name":"Nicolas","last_name":"Rodrigues","full_name":"Rodrigues, Nicolas"},{"first_name":"Roberto","full_name":"Sermier, Roberto","last_name":"Sermier"},{"first_name":"Daniel","full_name":"Jeffries, Daniel","last_name":"Jeffries"},{"full_name":"Perrin, Nicolas","last_name":"Perrin","first_name":"Nicolas"}],"publist_id":"7714","title":"Tissue specificity and dynamics of sex biased gene expression in a common frog population with differentiated, yet homomorphic, sex chromosomes","citation":{"chicago":"Ma, Wen, Paris Veltsos, Melissa A Toups, Nicolas Rodrigues, Roberto Sermier, Daniel Jeffries, and Nicolas Perrin. “Tissue Specificity and Dynamics of Sex Biased Gene Expression in a Common Frog Population with Differentiated, yet Homomorphic, Sex Chromosomes.” Genes. MDPI AG, 2018. https://doi.org/10.3390/genes9060294.","ista":"Ma W, Veltsos P, Toups MA, Rodrigues N, Sermier R, Jeffries D, Perrin N. 2018. Tissue specificity and dynamics of sex biased gene expression in a common frog population with differentiated, yet homomorphic, sex chromosomes. Genes. 9(6), 294.","mla":"Ma, Wen, et al. “Tissue Specificity and Dynamics of Sex Biased Gene Expression in a Common Frog Population with Differentiated, yet Homomorphic, Sex Chromosomes.” Genes, vol. 9, no. 6, 294, MDPI AG, 2018, doi:10.3390/genes9060294.","ama":"Ma W, Veltsos P, Toups MA, et al. Tissue specificity and dynamics of sex biased gene expression in a common frog population with differentiated, yet homomorphic, sex chromosomes. Genes. 2018;9(6). doi:10.3390/genes9060294","apa":"Ma, W., Veltsos, P., Toups, M. A., Rodrigues, N., Sermier, R., Jeffries, D., & Perrin, N. (2018). Tissue specificity and dynamics of sex biased gene expression in a common frog population with differentiated, yet homomorphic, sex chromosomes. Genes. MDPI AG. https://doi.org/10.3390/genes9060294","short":"W. Ma, P. Veltsos, M.A. Toups, N. Rodrigues, R. Sermier, D. Jeffries, N. Perrin, Genes 9 (2018).","ieee":"W. Ma et al., “Tissue specificity and dynamics of sex biased gene expression in a common frog population with differentiated, yet homomorphic, sex chromosomes,” Genes, vol. 9, no. 6. MDPI AG, 2018."},"user_id":"c635000d-4b10-11ee-a964-aac5a93f6ac1","article_number":"294","date_created":"2018-12-11T11:45:09Z","doi":"10.3390/genes9060294","date_published":"2018-06-12T00:00:00Z","year":"2018","has_accepted_license":"1","isi":1,"publication":"Genes","day":"12","oa":1,"quality_controlled":"1","publisher":"MDPI AG"},{"publist_id":"7273","author":[{"orcid":"0000-0001-7782-4436","full_name":"Chalk, Matthew J","last_name":"Chalk","first_name":"Matthew J","id":"2BAAC544-F248-11E8-B48F-1D18A9856A87"},{"first_name":"Olivier","last_name":"Marre","full_name":"Marre, Olivier"},{"id":"3D494DCA-F248-11E8-B48F-1D18A9856A87","first_name":"Gasper","last_name":"Tkacik","full_name":"Tkacik, Gasper","orcid":"0000-0002-6699-1455"}],"article_processing_charge":"No","external_id":{"isi":["000419128700049"]},"title":"Toward a unified theory of efficient, predictive, and sparse coding","citation":{"short":"M.J. Chalk, O. Marre, G. Tkačik, PNAS 115 (2018) 186–191.","ieee":"M. J. Chalk, O. Marre, and G. Tkačik, “Toward a unified theory of efficient, predictive, and sparse coding,” PNAS, vol. 115, no. 1. National Academy of Sciences, pp. 186–191, 2018.","apa":"Chalk, M. J., Marre, O., & Tkačik, G. (2018). Toward a unified theory of efficient, predictive, and sparse coding. PNAS. National Academy of Sciences. https://doi.org/10.1073/pnas.1711114115","ama":"Chalk MJ, Marre O, Tkačik G. Toward a unified theory of efficient, predictive, and sparse coding. PNAS. 2018;115(1):186-191. doi:10.1073/pnas.1711114115","mla":"Chalk, Matthew J., et al. “Toward a Unified Theory of Efficient, Predictive, and Sparse Coding.” PNAS, vol. 115, no. 1, National Academy of Sciences, 2018, pp. 186–91, doi:10.1073/pnas.1711114115.","ista":"Chalk MJ, Marre O, Tkačik G. 2018. Toward a unified theory of efficient, predictive, and sparse coding. PNAS. 115(1), 186–191.","chicago":"Chalk, Matthew J, Olivier Marre, and Gašper Tkačik. “Toward a Unified Theory of Efficient, Predictive, and Sparse Coding.” PNAS. National Academy of Sciences, 2018. https://doi.org/10.1073/pnas.1711114115."},"user_id":"c635000d-4b10-11ee-a964-aac5a93f6ac1","project":[{"_id":"254D1A94-B435-11E9-9278-68D0E5697425","call_identifier":"FWF","name":"Sensitivity to higher-order statistics in natural scenes","grant_number":"P 25651-N26"}],"page":"186 - 191","date_published":"2018-01-02T00:00:00Z","doi":"10.1073/pnas.1711114115","date_created":"2018-12-11T11:47:04Z","isi":1,"year":"2018","day":"02","publication":"PNAS","publisher":"National Academy of Sciences","quality_controlled":"1","oa":1,"department":[{"_id":"GaTk"}],"date_updated":"2023-09-19T10:16:35Z","type":"journal_article","status":"public","_id":"543","volume":115,"issue":"1","publication_status":"published","language":[{"iso":"eng"}],"scopus_import":"1","main_file_link":[{"url":"https://doi.org/10.1101/152660 ","open_access":"1"}],"month":"01","intvolume":" 115","abstract":[{"lang":"eng","text":"A central goal in theoretical neuroscience is to predict the response properties of sensory neurons from first principles. To this end, “efficient coding” posits that sensory neurons encode maximal information about their inputs given internal constraints. There exist, however, many variants of efficient coding (e.g., redundancy reduction, different formulations of predictive coding, robust coding, sparse coding, etc.), differing in their regimes of applicability, in the relevance of signals to be encoded, and in the choice of constraints. It is unclear how these types of efficient coding relate or what is expected when different coding objectives are combined. Here we present a unified framework that encompasses previously proposed efficient coding models and extends to unique regimes. We show that optimizing neural responses to encode predictive information can lead them to either correlate or decorrelate their inputs, depending on the stimulus statistics; in contrast, at low noise, efficiently encoding the past always predicts decorrelation. Later, we investigate coding of naturalistic movies and show that qualitatively different types of visual motion tuning and levels of response sparsity are predicted, depending on whether the objective is to recover the past or predict the future. Our approach promises a way to explain the observed diversity of sensory neural responses, as due to multiple functional goals and constraints fulfilled by different cell types and/or circuits."}],"oa_version":"Submitted Version"},{"date_updated":"2023-09-19T10:13:55Z","department":[{"_id":"EdHa"}],"_id":"421","status":"public","type":"journal_article","language":[{"iso":"eng"}],"publication_status":"published","issue":"4","volume":114,"oa_version":"Submitted Version","abstract":[{"text":"Cell shape is determined by a balance of intrinsic properties of the cell as well as its mechanochemical environment. Inhomogeneous shape changes underlie many morphogenetic events and involve spatial gradients in active cellular forces induced by complex chemical signaling. Here, we introduce a mechanochemical model based on the notion that cell shape changes may be induced by external diffusible biomolecules that influence cellular contractility (or equivalently, adhesions) in a concentration-dependent manner—and whose spatial profile in turn is affected by cell shape. We map out theoretically the possible interplay between chemical concentration and cellular structure. Besides providing a direct route to spatial gradients in cell shape profiles in tissues, we show that the dependence on cell shape helps create robust mechanochemical gradients.","lang":"eng"}],"intvolume":" 114","month":"02","main_file_link":[{"open_access":"1","url":"https://arxiv.org/abs/1709.01486"}],"scopus_import":"1","user_id":"c635000d-4b10-11ee-a964-aac5a93f6ac1","citation":{"mla":"Dasbiswas, Kinjal, et al. “Theory of Eppithelial Cell Shape Transitions Induced by Mechanoactive Chemical Gradients.” Biophysical Journal, vol. 114, no. 4, Biophysical Society, 2018, pp. 968–77, doi:10.1016/j.bpj.2017.12.022.","short":"K. Dasbiswas, E.B. Hannezo, N. Gov, Biophysical Journal 114 (2018) 968–977.","ieee":"K. Dasbiswas, E. B. Hannezo, and N. Gov, “Theory of eppithelial cell shape transitions induced by mechanoactive chemical gradients,” Biophysical Journal, vol. 114, no. 4. Biophysical Society, pp. 968–977, 2018.","ama":"Dasbiswas K, Hannezo EB, Gov N. Theory of eppithelial cell shape transitions induced by mechanoactive chemical gradients. Biophysical Journal. 2018;114(4):968-977. doi:10.1016/j.bpj.2017.12.022","apa":"Dasbiswas, K., Hannezo, E. B., & Gov, N. (2018). Theory of eppithelial cell shape transitions induced by mechanoactive chemical gradients. Biophysical Journal. Biophysical Society. https://doi.org/10.1016/j.bpj.2017.12.022","chicago":"Dasbiswas, Kinjal, Edouard B Hannezo, and Nir Gov. “Theory of Eppithelial Cell Shape Transitions Induced by Mechanoactive Chemical Gradients.” Biophysical Journal. Biophysical Society, 2018. https://doi.org/10.1016/j.bpj.2017.12.022.","ista":"Dasbiswas K, Hannezo EB, Gov N. 2018. Theory of eppithelial cell shape transitions induced by mechanoactive chemical gradients. Biophysical Journal. 114(4), 968–977."},"title":"Theory of eppithelial cell shape transitions induced by mechanoactive chemical gradients","external_id":{"arxiv":["1709.01486"],"isi":["000428016700021"]},"article_processing_charge":"No","author":[{"last_name":"Dasbiswas","full_name":"Dasbiswas, Kinjal","first_name":"Kinjal"},{"last_name":"Hannezo","orcid":"0000-0001-6005-1561","full_name":"Hannezo, Claude-Edouard B","id":"3A9DB764-F248-11E8-B48F-1D18A9856A87","first_name":"Claude-Edouard B"},{"first_name":"Nir","full_name":"Gov, Nir","last_name":"Gov"}],"publist_id":"7403","publication":"Biophysical Journal","day":"27","year":"2018","isi":1,"date_created":"2018-12-11T11:46:23Z","doi":"10.1016/j.bpj.2017.12.022","date_published":"2018-02-27T00:00:00Z","page":"968 - 977","oa":1,"publisher":"Biophysical Society","quality_controlled":"1"}]