@article{8163,
abstract = {Fejes Tóth [3] studied approximations of smooth surfaces in three-space by piecewise flat triangular meshes with a given number of vertices on the surface that are optimal with respect to Hausdorff distance. He proves that this Hausdorff distance decreases inversely proportional with the number of vertices of the approximating mesh if the surface is convex. He also claims that this Hausdorff distance is inversely proportional to the square of the number of vertices for a specific non-convex surface, namely a one-sheeted hyperboloid of revolution bounded by two congruent circles. We refute this claim, and show that the asymptotic behavior of the Hausdorff distance is linear, that is the same as for convex surfaces.},
author = {Vegter, Gert and Wintraecken, Mathijs},
issn = {1588-2896},
journal = {Studia Scientiarum Mathematicarum Hungarica},
number = {2},
pages = {193--199},
publisher = {AKJournals},
title = {{Refutation of a claim made by Fejes Tóth on the accuracy of surface meshes}},
doi = {10.1556/012.2020.57.2.1454},
volume = {57},
year = {2020},
}
@article{8162,
author = {Laukoter, Susanne and Pauler, Florian and Beattie, Robert J and Amberg, Nicole and Hansen, Andi H and Streicher, Carmen and Penz, Thomas and Bock, Christoph and Hippenmeyer, Simon},
issn = {0896-6273},
journal = {Neuron},
number = {9},
pages = {1--20},
publisher = {Elsevier},
title = {{Cell-type specificity of genomic imprinting in cerebral cortex}},
doi = {10.1016/j.neuron.2020.06.031},
volume = {107},
year = {2020},
}
@article{7389,
abstract = {Recently Kloeckner described the structure of the isometry group of the quadratic Wasserstein space W_2(R^n). It turned out that the case of the real line is exceptional in the sense that there exists an exotic isometry flow. Following this line of investigation, we compute Isom(W_p(R)), the isometry group of the Wasserstein space
W_p(R) for all p \in [1,\infty) \setminus {2}. We show that W_2(R) is also exceptional regarding the
parameter p: W_p(R) is isometrically rigid if and only if p is not equal to 2. Regarding the underlying
space, we prove that the exceptionality of p = 2 disappears if we replace R by the compact
interval [0,1]. Surprisingly, in that case, W_p([0,1]) is isometrically rigid if and only if
p is not equal to 1. Moreover, W_1([0,1]) admits isometries that split mass, and Isom(W_1([0,1]))
cannot be embedded into Isom(W_1(R)).},
author = {Geher, Gyorgy Pal and Titkos, Tamas and Virosztek, Daniel},
issn = {10886850},
journal = {Transactions of the American Mathematical Society},
keywords = {Wasserstein space, isometric embeddings, isometric rigidity, exotic isometry flow},
number = {8},
pages = {5855--5883},
publisher = {American Mathematical Society},
title = {{Isometric study of Wasserstein spaces - the real line}},
doi = {10.1090/tran/8113},
volume = {373},
year = {2020},
}
@phdthesis{8156,
abstract = {We present solutions to several problems originating from geometry and discrete mathematics: existence of equipartitions, maps without Tverberg multiple points, and inscribing quadrilaterals. Equivariant obstruction theory is the natural topological approach to these type of questions. However, for the specific problems we consider it had yielded only partial or no results. We get our results by complementing equivariant obstruction theory with other techniques from topology and geometry.},
author = {Avvakumov, Sergey},
pages = {119},
publisher = {IST Austria},
title = {{Topological methods in geometry and discrete mathematics}},
doi = {10.15479/AT:ISTA:8156},
year = {2020},
}
@unpublished{7675,
abstract = {In prokaryotes, thermodynamic models of gene regulation provide a highly quantitative mapping from promoter sequences to gene expression levels that is compatible with in vivo and in vitro bio-physical measurements. Such concordance has not been achieved for models of enhancer function in eukaryotes. In equilibrium models, it is difficult to reconcile the reported short transcription factor (TF) residence times on the DNA with the high specificity of regulation. In non-equilibrium models, progress is difficult due to an explosion in the number of parameters. Here, we navigate this complexity by looking for minimal non-equilibrium enhancer models that yield desired regulatory phenotypes: low TF residence time, high specificity and tunable cooperativity. We find that a single extra parameter, interpretable as the “linking rate” by which bound TFs interact with Mediator components, enables our models to escape equilibrium bounds and access optimal regulatory phenotypes, while remaining consistent with the reported phenomenology and simple enough to be inferred from upcoming experiments. We further find that high specificity in non-equilibrium models is in a tradeoff with gene expression noise, predicting bursty dynamics — an experimentally-observed hallmark of eukaryotic transcription. By drastically reducing the vast parameter space to a much smaller subspace that optimally realizes biological function prior to inference from data, our normative approach holds promise for mathematical models in systems biology.},
author = {Grah, Rok and Zoller, Benjamin and Tkačik, Gašper},
booktitle = {bioRxiv},
pages = {11},
publisher = {Cold Spring Harbor Laboratory},
title = {{Normative models of enhancer function}},
year = {2020},
}