--- _id: '10413' abstract: - lang: eng text: Motivated by the recent introduction of the intrinsic semilattice entropy, we study generalized quasi-metric semilattices and their categories. We investigate the relationship between these objects and generalized semivaluations, extending Nakamura and Schellekens' approach. Finally, we use this correspondence to compare the intrinsic semilattice entropy and the semigroup entropy induced in particular situations, like sets, torsion abelian groups and vector spaces. acknowledgement: Dedicated to the memory of Hans-Peter Künzi. article_number: '107916' article_processing_charge: No article_type: original author: - first_name: Dikran full_name: Dikranjan, Dikran last_name: Dikranjan - first_name: Anna full_name: Giordano Bruno, Anna last_name: Giordano Bruno - first_name: Hans Peter full_name: Künzi, Hans Peter last_name: Künzi - first_name: Nicolò full_name: Zava, Nicolò id: c8b3499c-7a77-11eb-b046-aa368cbbf2ad last_name: Zava orcid: 0000-0001-8686-1888 - first_name: Daniele full_name: Toller, Daniele last_name: Toller citation: ama: Dikranjan D, Giordano Bruno A, Künzi HP, Zava N, Toller D. Generalized quasi-metric semilattices. Topology and its Applications. 2022;309. doi:10.1016/j.topol.2021.107916 apa: Dikranjan, D., Giordano Bruno, A., Künzi, H. P., Zava, N., & Toller, D. (2022). Generalized quasi-metric semilattices. Topology and Its Applications. Elsevier. https://doi.org/10.1016/j.topol.2021.107916 chicago: Dikranjan, Dikran, Anna Giordano Bruno, Hans Peter Künzi, Nicolò Zava, and Daniele Toller. “Generalized Quasi-Metric Semilattices.” Topology and Its Applications. Elsevier, 2022. https://doi.org/10.1016/j.topol.2021.107916. ieee: D. Dikranjan, A. Giordano Bruno, H. P. Künzi, N. Zava, and D. Toller, “Generalized quasi-metric semilattices,” Topology and its Applications, vol. 309. Elsevier, 2022. ista: Dikranjan D, Giordano Bruno A, Künzi HP, Zava N, Toller D. 2022. Generalized quasi-metric semilattices. Topology and its Applications. 309, 107916. mla: Dikranjan, Dikran, et al. “Generalized Quasi-Metric Semilattices.” Topology and Its Applications, vol. 309, 107916, Elsevier, 2022, doi:10.1016/j.topol.2021.107916. short: D. Dikranjan, A. Giordano Bruno, H.P. Künzi, N. Zava, D. Toller, Topology and Its Applications 309 (2022). date_created: 2021-12-05T23:01:44Z date_published: 2022-03-15T00:00:00Z date_updated: 2023-08-02T13:33:24Z day: '15' department: - _id: HeEd doi: 10.1016/j.topol.2021.107916 external_id: isi: - '000791838800012' intvolume: ' 309' isi: 1 language: - iso: eng month: '03' oa_version: None publication: Topology and its Applications publication_identifier: issn: - 0166-8641 publication_status: published publisher: Elsevier quality_controlled: '1' scopus_import: '1' status: public title: Generalized quasi-metric semilattices type: journal_article user_id: 4359f0d1-fa6c-11eb-b949-802e58b17ae8 volume: 309 year: '2022' ... --- _id: '10773' abstract: - lang: eng text: The Voronoi tessellation in Rd is defined by locally minimizing the power distance to given weighted points. Symmetrically, the Delaunay mosaic can be defined by locally maximizing the negative power distance to other such points. We prove that the average of the two piecewise quadratic functions is piecewise linear, and that all three functions have the same critical points and values. Discretizing the two piecewise quadratic functions, we get the alpha shapes as sublevel sets of the discrete function on the Delaunay mosaic, and analogous shapes as superlevel sets of the discrete function on the Voronoi tessellation. For the same non-critical value, the corresponding shapes are disjoint, separated by a narrow channel that contains no critical points but the entire level set of the piecewise linear function. acknowledgement: Open access funding provided by the Institute of Science and Technology (IST Austria). article_processing_charge: Yes (via OA deal) article_type: original author: - first_name: Ranita full_name: Biswas, Ranita id: 3C2B033E-F248-11E8-B48F-1D18A9856A87 last_name: Biswas orcid: 0000-0002-5372-7890 - first_name: Sebastiano full_name: Cultrera Di Montesano, Sebastiano id: 34D2A09C-F248-11E8-B48F-1D18A9856A87 last_name: Cultrera Di Montesano orcid: 0000-0001-6249-0832 - first_name: Herbert full_name: Edelsbrunner, Herbert id: 3FB178DA-F248-11E8-B48F-1D18A9856A87 last_name: Edelsbrunner orcid: 0000-0002-9823-6833 - first_name: Morteza full_name: Saghafian, Morteza last_name: Saghafian citation: ama: Biswas R, Cultrera di Montesano S, Edelsbrunner H, Saghafian M. Continuous and discrete radius functions on Voronoi tessellations and Delaunay mosaics. Discrete and Computational Geometry. 2022;67:811-842. doi:10.1007/s00454-022-00371-2 apa: Biswas, R., Cultrera di Montesano, S., Edelsbrunner, H., & Saghafian, M. (2022). Continuous and discrete radius functions on Voronoi tessellations and Delaunay mosaics. Discrete and Computational Geometry. Springer Nature. https://doi.org/10.1007/s00454-022-00371-2 chicago: Biswas, Ranita, Sebastiano Cultrera di Montesano, Herbert Edelsbrunner, and Morteza Saghafian. “Continuous and Discrete Radius Functions on Voronoi Tessellations and Delaunay Mosaics.” Discrete and Computational Geometry. Springer Nature, 2022. https://doi.org/10.1007/s00454-022-00371-2. ieee: R. Biswas, S. Cultrera di Montesano, H. Edelsbrunner, and M. Saghafian, “Continuous and discrete radius functions on Voronoi tessellations and Delaunay mosaics,” Discrete and Computational Geometry, vol. 67. Springer Nature, pp. 811–842, 2022. ista: Biswas R, Cultrera di Montesano S, Edelsbrunner H, Saghafian M. 2022. Continuous and discrete radius functions on Voronoi tessellations and Delaunay mosaics. Discrete and Computational Geometry. 67, 811–842. mla: Biswas, Ranita, et al. “Continuous and Discrete Radius Functions on Voronoi Tessellations and Delaunay Mosaics.” Discrete and Computational Geometry, vol. 67, Springer Nature, 2022, pp. 811–42, doi:10.1007/s00454-022-00371-2. short: R. Biswas, S. Cultrera di Montesano, H. Edelsbrunner, M. Saghafian, Discrete and Computational Geometry 67 (2022) 811–842. date_created: 2022-02-20T23:01:34Z date_published: 2022-04-01T00:00:00Z date_updated: 2023-08-02T14:31:25Z day: '01' ddc: - '510' department: - _id: HeEd doi: 10.1007/s00454-022-00371-2 external_id: isi: - '000752175300002' file: - access_level: open_access checksum: 9383d3b70561bacee905e335dc922680 content_type: application/pdf creator: dernst date_created: 2022-08-02T06:07:55Z date_updated: 2022-08-02T06:07:55Z file_id: '11718' file_name: 2022_DiscreteCompGeometry_Biswas.pdf file_size: 2518111 relation: main_file success: 1 file_date_updated: 2022-08-02T06:07:55Z has_accepted_license: '1' intvolume: ' 67' isi: 1 language: - iso: eng month: '04' oa: 1 oa_version: Published Version page: 811-842 publication: Discrete and Computational Geometry publication_identifier: eissn: - 1432-0444 issn: - 0179-5376 publication_status: published publisher: Springer Nature quality_controlled: '1' scopus_import: '1' status: public title: Continuous and discrete radius functions on Voronoi tessellations and Delaunay mosaics tmp: image: /images/cc_by.png legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0) short: CC BY (4.0) type: journal_article user_id: 4359f0d1-fa6c-11eb-b949-802e58b17ae8 volume: 67 year: '2022' ... --- _id: '10828' abstract: - lang: eng text: Digital images enable quantitative analysis of material properties at micro and macro length scales, but choosing an appropriate resolution when acquiring the image is challenging. A high resolution means longer image acquisition and larger data requirements for a given sample, but if the resolution is too low, significant information may be lost. This paper studies the impact of changes in resolution on persistent homology, a tool from topological data analysis that provides a signature of structure in an image across all length scales. Given prior information about a function, the geometry of an object, or its density distribution at a given resolution, we provide methods to select the coarsest resolution yielding results within an acceptable tolerance. We present numerical case studies for an illustrative synthetic example and samples from porous materials where the theoretical bounds are unknown. article_processing_charge: No author: - first_name: Teresa full_name: Heiss, Teresa id: 4879BB4E-F248-11E8-B48F-1D18A9856A87 last_name: Heiss orcid: 0000-0002-1780-2689 - first_name: Sarah full_name: Tymochko, Sarah last_name: Tymochko - first_name: Brittany full_name: Story, Brittany last_name: Story - first_name: Adélie full_name: Garin, Adélie last_name: Garin - first_name: Hoa full_name: Bui, Hoa last_name: Bui - first_name: Bea full_name: Bleile, Bea last_name: Bleile - first_name: Vanessa full_name: Robins, Vanessa last_name: Robins citation: ama: 'Heiss T, Tymochko S, Story B, et al. The impact of changes in resolution on the persistent homology of images. In: 2021 IEEE International Conference on Big Data. IEEE; 2022:3824-3834. doi:10.1109/BigData52589.2021.9671483' apa: 'Heiss, T., Tymochko, S., Story, B., Garin, A., Bui, H., Bleile, B., & Robins, V. (2022). The impact of changes in resolution on the persistent homology of images. In 2021 IEEE International Conference on Big Data (pp. 3824–3834). Orlando, FL, United States; Virtuell: IEEE. https://doi.org/10.1109/BigData52589.2021.9671483' chicago: Heiss, Teresa, Sarah Tymochko, Brittany Story, Adélie Garin, Hoa Bui, Bea Bleile, and Vanessa Robins. “The Impact of Changes in Resolution on the Persistent Homology of Images.” In 2021 IEEE International Conference on Big Data, 3824–34. IEEE, 2022. https://doi.org/10.1109/BigData52589.2021.9671483. ieee: T. Heiss et al., “The impact of changes in resolution on the persistent homology of images,” in 2021 IEEE International Conference on Big Data, Orlando, FL, United States; Virtuell, 2022, pp. 3824–3834. ista: 'Heiss T, Tymochko S, Story B, Garin A, Bui H, Bleile B, Robins V. 2022. The impact of changes in resolution on the persistent homology of images. 2021 IEEE International Conference on Big Data. Big Data: International Conference on Big Data, 3824–3834.' mla: Heiss, Teresa, et al. “The Impact of Changes in Resolution on the Persistent Homology of Images.” 2021 IEEE International Conference on Big Data, IEEE, 2022, pp. 3824–34, doi:10.1109/BigData52589.2021.9671483. short: T. Heiss, S. Tymochko, B. Story, A. Garin, H. Bui, B. Bleile, V. Robins, in:, 2021 IEEE International Conference on Big Data, IEEE, 2022, pp. 3824–3834. conference: end_date: 2021-12-18 location: Orlando, FL, United States; Virtuell name: 'Big Data: International Conference on Big Data' start_date: 2021-12-15 date_created: 2022-03-06T23:01:53Z date_published: 2022-01-13T00:00:00Z date_updated: 2023-08-02T14:44:21Z day: '13' department: - _id: HeEd doi: 10.1109/BigData52589.2021.9671483 external_id: arxiv: - '2111.05663' isi: - '000800559503126' isi: 1 language: - iso: eng main_file_link: - open_access: '1' url: https://arxiv.org/abs/2111.05663 month: '01' oa: 1 oa_version: Preprint page: 3824-3834 publication: 2021 IEEE International Conference on Big Data publication_identifier: isbn: - '9781665439022' publication_status: published publisher: IEEE quality_controlled: '1' scopus_import: '1' status: public title: The impact of changes in resolution on the persistent homology of images type: conference user_id: 4359f0d1-fa6c-11eb-b949-802e58b17ae8 year: '2022' ... --- _id: '11545' abstract: - lang: eng text: "We classify contravariant pairings between standard Whittaker modules and Verma modules over a complex semisimple Lie algebra. These contravariant pairings are useful in extending several classical techniques for category O to the Miličić–Soergel category N . We introduce a class of costandard modules which generalize dual Verma modules, and describe canonical maps from standard to costandard modules in terms of contravariant pairings.\r\nWe show that costandard modules have unique irreducible submodules and share the same composition factors as the corresponding standard Whittaker modules. We show that costandard modules give an algebraic characterization of the global sections of costandard twisted Harish-Chandra sheaves on the associated flag variety, which are defined using holonomic duality of D-modules. We prove that with these costandard modules, blocks of category\r\nN have the structure of highest weight categories and we establish a BGG reciprocity theorem for N ." acknowledgement: We thank Catharina Stroppel and Jens Niklas Eberhardt for interesting discussions. The first author acknowledges the support of the European Union's Horizon 2020 research and innovation programme under the Marie Skłodowska-Curie Grant Agreement No. 754411. The second author is supported by the National Science Foundation Award No. 1803059 and the Australian Research Council grant DP170101579. article_processing_charge: Yes (via OA deal) article_type: original author: - first_name: Adam full_name: Brown, Adam id: 70B7FDF6-608D-11E9-9333-8535E6697425 last_name: Brown - first_name: Anna full_name: Romanov, Anna last_name: Romanov citation: ama: Brown A, Romanov A. Contravariant pairings between standard Whittaker modules and Verma modules. Journal of Algebra. 2022;609(11):145-179. doi:10.1016/j.jalgebra.2022.06.017 apa: Brown, A., & Romanov, A. (2022). Contravariant pairings between standard Whittaker modules and Verma modules. Journal of Algebra. Elsevier. https://doi.org/10.1016/j.jalgebra.2022.06.017 chicago: Brown, Adam, and Anna Romanov. “Contravariant Pairings between Standard Whittaker Modules and Verma Modules.” Journal of Algebra. Elsevier, 2022. https://doi.org/10.1016/j.jalgebra.2022.06.017. ieee: A. Brown and A. Romanov, “Contravariant pairings between standard Whittaker modules and Verma modules,” Journal of Algebra, vol. 609, no. 11. Elsevier, pp. 145–179, 2022. ista: Brown A, Romanov A. 2022. Contravariant pairings between standard Whittaker modules and Verma modules. Journal of Algebra. 609(11), 145–179. mla: Brown, Adam, and Anna Romanov. “Contravariant Pairings between Standard Whittaker Modules and Verma Modules.” Journal of Algebra, vol. 609, no. 11, Elsevier, 2022, pp. 145–79, doi:10.1016/j.jalgebra.2022.06.017. short: A. Brown, A. Romanov, Journal of Algebra 609 (2022) 145–179. date_created: 2022-07-08T11:40:07Z date_published: 2022-11-01T00:00:00Z date_updated: 2023-08-03T11:56:30Z day: '01' ddc: - '510' department: - _id: HeEd doi: 10.1016/j.jalgebra.2022.06.017 ec_funded: 1 external_id: isi: - '000861841100004' file: - access_level: open_access checksum: 82abaee3d7837f703e499a9ecbb25b7c content_type: application/pdf creator: dernst date_created: 2023-02-02T07:32:48Z date_updated: 2023-02-02T07:32:48Z file_id: '12473' file_name: 2022_JournalAlgebra_Brown.pdf file_size: 582962 relation: main_file success: 1 file_date_updated: 2023-02-02T07:32:48Z has_accepted_license: '1' intvolume: ' 609' isi: 1 issue: '11' keyword: - Algebra and Number Theory language: - iso: eng month: '11' oa: 1 oa_version: Published Version page: 145-179 project: - _id: 260C2330-B435-11E9-9278-68D0E5697425 call_identifier: H2020 grant_number: '754411' name: ISTplus - Postdoctoral Fellowships publication: Journal of Algebra publication_identifier: issn: - 0021-8693 publication_status: published publisher: Elsevier quality_controlled: '1' scopus_import: '1' status: public title: Contravariant pairings between standard Whittaker modules and Verma modules tmp: image: /images/cc_by.png legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0) short: CC BY (4.0) type: journal_article user_id: 4359f0d1-fa6c-11eb-b949-802e58b17ae8 volume: 609 year: '2022' ... --- _id: '10754' abstract: - lang: eng text: Targeting dysregulated Ca2+ signaling in cancer cells is an emerging chemotherapy approach. We previously reported that store-operated Ca2+ entry (SOCE) blockers, such as RP4010, are promising antitumor drugs for esophageal cancer. As a tyrosine kinase inhibitor (TKI), afatinib received FDA approval to be used in targeted therapy for patients with EGFR mutation-positive cancers. While preclinical studies and clinical trials have shown that afatinib has benefits for esophageal cancer patients, it is not known whether a combination of afatinib and RP4010 could achieve better anticancer effects. Since TKI can alter intracellular Ca2+ dynamics through EGFR/phospholipase C-γ pathway, in this study, we evaluated the inhibitory effect of afatinib and RP4010 on intracellular Ca2+ oscillations in KYSE-150, a human esophageal squamous cell carcinoma cell line, using both experimental and mathematical simulations. Our mathematical simulation of Ca2+ oscillations could fit well with experimental data responding to afatinib or RP4010, both separately or in combination. Guided by simulation, we were able to identify a proper ratio of afatinib and RP4010 for combined treatment, and such a combination presented synergistic anticancer-effect evidence by experimental measurement of intracellular Ca2+ and cell proliferation. This intracellular Ca2+ dynamic-based mathematical simulation approach could be useful for a rapid and cost-effective evaluation of combined targeting therapy drugs. acknowledgement: "This work was partially supported by grants from National Institutes of Health (NIH) (R01 CA185055, S10OD0252300) and The University of Texas System STARs Award (to Z.P.),\r\nThe University of Texas at Arlington Interdisciplinary Research Program (to B.C., H.V.K. and Z.P.). " article_number: '1763' article_processing_charge: Yes article_type: original author: - first_name: Yan full_name: Chang, Yan last_name: Chang - first_name: Marah full_name: Funk, Marah last_name: Funk - first_name: Souvik full_name: Roy, Souvik last_name: Roy - first_name: Elizabeth R full_name: Stephenson, Elizabeth R id: 2D04F932-F248-11E8-B48F-1D18A9856A87 last_name: Stephenson orcid: 0000-0002-6862-208X - first_name: Sangyong full_name: Choi, Sangyong last_name: Choi - first_name: Hristo V. full_name: Kojouharov, Hristo V. last_name: Kojouharov - first_name: Benito full_name: Chen, Benito last_name: Chen - first_name: Zui full_name: Pan, Zui last_name: Pan citation: ama: Chang Y, Funk M, Roy S, et al. Developing a mathematical model of intracellular Calcium dynamics for evaluating combined anticancer effects of afatinib and RP4010 in esophageal cancer. International Journal of Molecular Sciences. 2022;23(3). doi:10.3390/ijms23031763 apa: Chang, Y., Funk, M., Roy, S., Stephenson, E. R., Choi, S., Kojouharov, H. V., … Pan, Z. (2022). Developing a mathematical model of intracellular Calcium dynamics for evaluating combined anticancer effects of afatinib and RP4010 in esophageal cancer. International Journal of Molecular Sciences. MDPI. https://doi.org/10.3390/ijms23031763 chicago: Chang, Yan, Marah Funk, Souvik Roy, Elizabeth R Stephenson, Sangyong Choi, Hristo V. Kojouharov, Benito Chen, and Zui Pan. “Developing a Mathematical Model of Intracellular Calcium Dynamics for Evaluating Combined Anticancer Effects of Afatinib and RP4010 in Esophageal Cancer.” International Journal of Molecular Sciences. MDPI, 2022. https://doi.org/10.3390/ijms23031763. ieee: Y. Chang et al., “Developing a mathematical model of intracellular Calcium dynamics for evaluating combined anticancer effects of afatinib and RP4010 in esophageal cancer,” International Journal of Molecular Sciences, vol. 23, no. 3. MDPI, 2022. ista: Chang Y, Funk M, Roy S, Stephenson ER, Choi S, Kojouharov HV, Chen B, Pan Z. 2022. Developing a mathematical model of intracellular Calcium dynamics for evaluating combined anticancer effects of afatinib and RP4010 in esophageal cancer. International Journal of Molecular Sciences. 23(3), 1763. mla: Chang, Yan, et al. “Developing a Mathematical Model of Intracellular Calcium Dynamics for Evaluating Combined Anticancer Effects of Afatinib and RP4010 in Esophageal Cancer.” International Journal of Molecular Sciences, vol. 23, no. 3, 1763, MDPI, 2022, doi:10.3390/ijms23031763. short: Y. Chang, M. Funk, S. Roy, E.R. Stephenson, S. Choi, H.V. Kojouharov, B. Chen, Z. Pan, International Journal of Molecular Sciences 23 (2022). date_created: 2022-02-13T23:01:35Z date_published: 2022-02-01T00:00:00Z date_updated: 2023-08-09T10:17:07Z day: '01' ddc: - '510' - '576' department: - _id: HeEd doi: 10.3390/ijms23031763 external_id: isi: - '000754773500001' file: - access_level: open_access checksum: 8890ad20c54e90dc58ad5ea97c902998 content_type: application/pdf creator: dernst date_created: 2022-02-14T07:46:30Z date_updated: 2022-02-14T07:46:30Z file_id: '10756' file_name: 2022_IJMS_Chang.pdf file_size: 24416183 relation: main_file success: 1 file_date_updated: 2022-02-14T07:46:30Z has_accepted_license: '1' intvolume: ' 23' isi: 1 issue: '3' language: - iso: eng month: '02' oa: 1 oa_version: Published Version publication: International Journal of Molecular Sciences publication_identifier: eissn: - '14220067' issn: - '16616596' publication_status: published publisher: MDPI quality_controlled: '1' scopus_import: '1' status: public title: Developing a mathematical model of intracellular Calcium dynamics for evaluating combined anticancer effects of afatinib and RP4010 in esophageal cancer tmp: image: /images/cc_by.png legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0) short: CC BY (4.0) type: journal_article user_id: 3E5EF7F0-F248-11E8-B48F-1D18A9856A87 volume: 23 year: '2022' ...