---
_id: '10413'
abstract:
- lang: eng
text: Motivated by the recent introduction of the intrinsic semilattice entropy,
we study generalized quasi-metric semilattices and their categories. We investigate
the relationship between these objects and generalized semivaluations, extending
Nakamura and Schellekens' approach. Finally, we use this correspondence to compare
the intrinsic semilattice entropy and the semigroup entropy induced in particular
situations, like sets, torsion abelian groups and vector spaces.
acknowledgement: Dedicated to the memory of Hans-Peter Künzi.
article_number: '107916'
article_processing_charge: No
article_type: original
author:
- first_name: Dikran
full_name: Dikranjan, Dikran
last_name: Dikranjan
- first_name: Anna
full_name: Giordano Bruno, Anna
last_name: Giordano Bruno
- first_name: Hans Peter
full_name: Künzi, Hans Peter
last_name: Künzi
- first_name: Nicolò
full_name: Zava, Nicolò
id: c8b3499c-7a77-11eb-b046-aa368cbbf2ad
last_name: Zava
orcid: 0000-0001-8686-1888
- first_name: Daniele
full_name: Toller, Daniele
last_name: Toller
citation:
ama: Dikranjan D, Giordano Bruno A, Künzi HP, Zava N, Toller D. Generalized quasi-metric
semilattices. Topology and its Applications. 2022;309. doi:10.1016/j.topol.2021.107916
apa: Dikranjan, D., Giordano Bruno, A., Künzi, H. P., Zava, N., & Toller, D.
(2022). Generalized quasi-metric semilattices. Topology and Its Applications.
Elsevier. https://doi.org/10.1016/j.topol.2021.107916
chicago: Dikranjan, Dikran, Anna Giordano Bruno, Hans Peter Künzi, Nicolò Zava,
and Daniele Toller. “Generalized Quasi-Metric Semilattices.” Topology and Its
Applications. Elsevier, 2022. https://doi.org/10.1016/j.topol.2021.107916.
ieee: D. Dikranjan, A. Giordano Bruno, H. P. Künzi, N. Zava, and D. Toller, “Generalized
quasi-metric semilattices,” Topology and its Applications, vol. 309. Elsevier,
2022.
ista: Dikranjan D, Giordano Bruno A, Künzi HP, Zava N, Toller D. 2022. Generalized
quasi-metric semilattices. Topology and its Applications. 309, 107916.
mla: Dikranjan, Dikran, et al. “Generalized Quasi-Metric Semilattices.” Topology
and Its Applications, vol. 309, 107916, Elsevier, 2022, doi:10.1016/j.topol.2021.107916.
short: D. Dikranjan, A. Giordano Bruno, H.P. Künzi, N. Zava, D. Toller, Topology
and Its Applications 309 (2022).
date_created: 2021-12-05T23:01:44Z
date_published: 2022-03-15T00:00:00Z
date_updated: 2023-08-02T13:33:24Z
day: '15'
department:
- _id: HeEd
doi: 10.1016/j.topol.2021.107916
external_id:
isi:
- '000791838800012'
intvolume: ' 309'
isi: 1
language:
- iso: eng
month: '03'
oa_version: None
publication: Topology and its Applications
publication_identifier:
issn:
- 0166-8641
publication_status: published
publisher: Elsevier
quality_controlled: '1'
scopus_import: '1'
status: public
title: Generalized quasi-metric semilattices
type: journal_article
user_id: 4359f0d1-fa6c-11eb-b949-802e58b17ae8
volume: 309
year: '2022'
...
---
_id: '10773'
abstract:
- lang: eng
text: The Voronoi tessellation in Rd is defined by locally minimizing the power
distance to given weighted points. Symmetrically, the Delaunay mosaic can be defined
by locally maximizing the negative power distance to other such points. We prove
that the average of the two piecewise quadratic functions is piecewise linear,
and that all three functions have the same critical points and values. Discretizing
the two piecewise quadratic functions, we get the alpha shapes as sublevel sets
of the discrete function on the Delaunay mosaic, and analogous shapes as superlevel
sets of the discrete function on the Voronoi tessellation. For the same non-critical
value, the corresponding shapes are disjoint, separated by a narrow channel that
contains no critical points but the entire level set of the piecewise linear function.
acknowledgement: Open access funding provided by the Institute of Science and Technology
(IST Austria).
article_processing_charge: Yes (via OA deal)
article_type: original
author:
- first_name: Ranita
full_name: Biswas, Ranita
id: 3C2B033E-F248-11E8-B48F-1D18A9856A87
last_name: Biswas
orcid: 0000-0002-5372-7890
- first_name: Sebastiano
full_name: Cultrera Di Montesano, Sebastiano
id: 34D2A09C-F248-11E8-B48F-1D18A9856A87
last_name: Cultrera Di Montesano
orcid: 0000-0001-6249-0832
- first_name: Herbert
full_name: Edelsbrunner, Herbert
id: 3FB178DA-F248-11E8-B48F-1D18A9856A87
last_name: Edelsbrunner
orcid: 0000-0002-9823-6833
- first_name: Morteza
full_name: Saghafian, Morteza
last_name: Saghafian
citation:
ama: Biswas R, Cultrera di Montesano S, Edelsbrunner H, Saghafian M. Continuous
and discrete radius functions on Voronoi tessellations and Delaunay mosaics. Discrete
and Computational Geometry. 2022;67:811-842. doi:10.1007/s00454-022-00371-2
apa: Biswas, R., Cultrera di Montesano, S., Edelsbrunner, H., & Saghafian, M.
(2022). Continuous and discrete radius functions on Voronoi tessellations and
Delaunay mosaics. Discrete and Computational Geometry. Springer Nature.
https://doi.org/10.1007/s00454-022-00371-2
chicago: Biswas, Ranita, Sebastiano Cultrera di Montesano, Herbert Edelsbrunner,
and Morteza Saghafian. “Continuous and Discrete Radius Functions on Voronoi Tessellations
and Delaunay Mosaics.” Discrete and Computational Geometry. Springer Nature,
2022. https://doi.org/10.1007/s00454-022-00371-2.
ieee: R. Biswas, S. Cultrera di Montesano, H. Edelsbrunner, and M. Saghafian, “Continuous
and discrete radius functions on Voronoi tessellations and Delaunay mosaics,”
Discrete and Computational Geometry, vol. 67. Springer Nature, pp. 811–842,
2022.
ista: Biswas R, Cultrera di Montesano S, Edelsbrunner H, Saghafian M. 2022. Continuous
and discrete radius functions on Voronoi tessellations and Delaunay mosaics. Discrete
and Computational Geometry. 67, 811–842.
mla: Biswas, Ranita, et al. “Continuous and Discrete Radius Functions on Voronoi
Tessellations and Delaunay Mosaics.” Discrete and Computational Geometry,
vol. 67, Springer Nature, 2022, pp. 811–42, doi:10.1007/s00454-022-00371-2.
short: R. Biswas, S. Cultrera di Montesano, H. Edelsbrunner, M. Saghafian, Discrete
and Computational Geometry 67 (2022) 811–842.
date_created: 2022-02-20T23:01:34Z
date_published: 2022-04-01T00:00:00Z
date_updated: 2023-08-02T14:31:25Z
day: '01'
ddc:
- '510'
department:
- _id: HeEd
doi: 10.1007/s00454-022-00371-2
external_id:
isi:
- '000752175300002'
file:
- access_level: open_access
checksum: 9383d3b70561bacee905e335dc922680
content_type: application/pdf
creator: dernst
date_created: 2022-08-02T06:07:55Z
date_updated: 2022-08-02T06:07:55Z
file_id: '11718'
file_name: 2022_DiscreteCompGeometry_Biswas.pdf
file_size: 2518111
relation: main_file
success: 1
file_date_updated: 2022-08-02T06:07:55Z
has_accepted_license: '1'
intvolume: ' 67'
isi: 1
language:
- iso: eng
month: '04'
oa: 1
oa_version: Published Version
page: 811-842
publication: Discrete and Computational Geometry
publication_identifier:
eissn:
- 1432-0444
issn:
- 0179-5376
publication_status: published
publisher: Springer Nature
quality_controlled: '1'
scopus_import: '1'
status: public
title: Continuous and discrete radius functions on Voronoi tessellations and Delaunay
mosaics
tmp:
image: /images/cc_by.png
legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
short: CC BY (4.0)
type: journal_article
user_id: 4359f0d1-fa6c-11eb-b949-802e58b17ae8
volume: 67
year: '2022'
...
---
_id: '10828'
abstract:
- lang: eng
text: Digital images enable quantitative analysis of material properties at micro
and macro length scales, but choosing an appropriate resolution when acquiring
the image is challenging. A high resolution means longer image acquisition and
larger data requirements for a given sample, but if the resolution is too low,
significant information may be lost. This paper studies the impact of changes
in resolution on persistent homology, a tool from topological data analysis that
provides a signature of structure in an image across all length scales. Given
prior information about a function, the geometry of an object, or its density
distribution at a given resolution, we provide methods to select the coarsest
resolution yielding results within an acceptable tolerance. We present numerical
case studies for an illustrative synthetic example and samples from porous materials
where the theoretical bounds are unknown.
article_processing_charge: No
author:
- first_name: Teresa
full_name: Heiss, Teresa
id: 4879BB4E-F248-11E8-B48F-1D18A9856A87
last_name: Heiss
orcid: 0000-0002-1780-2689
- first_name: Sarah
full_name: Tymochko, Sarah
last_name: Tymochko
- first_name: Brittany
full_name: Story, Brittany
last_name: Story
- first_name: Adélie
full_name: Garin, Adélie
last_name: Garin
- first_name: Hoa
full_name: Bui, Hoa
last_name: Bui
- first_name: Bea
full_name: Bleile, Bea
last_name: Bleile
- first_name: Vanessa
full_name: Robins, Vanessa
last_name: Robins
citation:
ama: 'Heiss T, Tymochko S, Story B, et al. The impact of changes in resolution on
the persistent homology of images. In: 2021 IEEE International Conference on
Big Data. IEEE; 2022:3824-3834. doi:10.1109/BigData52589.2021.9671483'
apa: 'Heiss, T., Tymochko, S., Story, B., Garin, A., Bui, H., Bleile, B., &
Robins, V. (2022). The impact of changes in resolution on the persistent homology
of images. In 2021 IEEE International Conference on Big Data (pp. 3824–3834).
Orlando, FL, United States; Virtuell: IEEE. https://doi.org/10.1109/BigData52589.2021.9671483'
chicago: Heiss, Teresa, Sarah Tymochko, Brittany Story, Adélie Garin, Hoa Bui, Bea
Bleile, and Vanessa Robins. “The Impact of Changes in Resolution on the Persistent
Homology of Images.” In 2021 IEEE International Conference on Big Data,
3824–34. IEEE, 2022. https://doi.org/10.1109/BigData52589.2021.9671483.
ieee: T. Heiss et al., “The impact of changes in resolution on the persistent
homology of images,” in 2021 IEEE International Conference on Big Data,
Orlando, FL, United States; Virtuell, 2022, pp. 3824–3834.
ista: 'Heiss T, Tymochko S, Story B, Garin A, Bui H, Bleile B, Robins V. 2022. The
impact of changes in resolution on the persistent homology of images. 2021 IEEE
International Conference on Big Data. Big Data: International Conference on Big
Data, 3824–3834.'
mla: Heiss, Teresa, et al. “The Impact of Changes in Resolution on the Persistent
Homology of Images.” 2021 IEEE International Conference on Big Data, IEEE,
2022, pp. 3824–34, doi:10.1109/BigData52589.2021.9671483.
short: T. Heiss, S. Tymochko, B. Story, A. Garin, H. Bui, B. Bleile, V. Robins,
in:, 2021 IEEE International Conference on Big Data, IEEE, 2022, pp. 3824–3834.
conference:
end_date: 2021-12-18
location: Orlando, FL, United States; Virtuell
name: 'Big Data: International Conference on Big Data'
start_date: 2021-12-15
date_created: 2022-03-06T23:01:53Z
date_published: 2022-01-13T00:00:00Z
date_updated: 2023-08-02T14:44:21Z
day: '13'
department:
- _id: HeEd
doi: 10.1109/BigData52589.2021.9671483
external_id:
arxiv:
- '2111.05663'
isi:
- '000800559503126'
isi: 1
language:
- iso: eng
main_file_link:
- open_access: '1'
url: https://arxiv.org/abs/2111.05663
month: '01'
oa: 1
oa_version: Preprint
page: 3824-3834
publication: 2021 IEEE International Conference on Big Data
publication_identifier:
isbn:
- '9781665439022'
publication_status: published
publisher: IEEE
quality_controlled: '1'
scopus_import: '1'
status: public
title: The impact of changes in resolution on the persistent homology of images
type: conference
user_id: 4359f0d1-fa6c-11eb-b949-802e58b17ae8
year: '2022'
...
---
_id: '11545'
abstract:
- lang: eng
text: "We classify contravariant pairings between standard Whittaker modules and
Verma modules over a complex semisimple Lie algebra. These contravariant pairings
are useful in extending several classical techniques for category O to the Miličić–Soergel
category N . We introduce a class of costandard modules which generalize dual
Verma modules, and describe canonical maps from standard to costandard modules
in terms of contravariant pairings.\r\nWe show that costandard modules have unique
irreducible submodules and share the same composition factors as the corresponding
standard Whittaker modules. We show that costandard modules give an algebraic
characterization of the global sections of costandard twisted Harish-Chandra sheaves
on the associated flag variety, which are defined using holonomic duality of D-modules.
We prove that with these costandard modules, blocks of category\r\nN have the
structure of highest weight categories and we establish a BGG reciprocity theorem
for N ."
acknowledgement: We thank Catharina Stroppel and Jens Niklas Eberhardt for interesting
discussions. The first author acknowledges the support of the European Union's Horizon
2020 research and innovation programme under the Marie Skłodowska-Curie Grant Agreement
No. 754411. The second author is supported by the National Science Foundation Award
No. 1803059 and the Australian Research Council grant DP170101579.
article_processing_charge: Yes (via OA deal)
article_type: original
author:
- first_name: Adam
full_name: Brown, Adam
id: 70B7FDF6-608D-11E9-9333-8535E6697425
last_name: Brown
- first_name: Anna
full_name: Romanov, Anna
last_name: Romanov
citation:
ama: Brown A, Romanov A. Contravariant pairings between standard Whittaker modules
and Verma modules. Journal of Algebra. 2022;609(11):145-179. doi:10.1016/j.jalgebra.2022.06.017
apa: Brown, A., & Romanov, A. (2022). Contravariant pairings between standard
Whittaker modules and Verma modules. Journal of Algebra. Elsevier. https://doi.org/10.1016/j.jalgebra.2022.06.017
chicago: Brown, Adam, and Anna Romanov. “Contravariant Pairings between Standard
Whittaker Modules and Verma Modules.” Journal of Algebra. Elsevier, 2022.
https://doi.org/10.1016/j.jalgebra.2022.06.017.
ieee: A. Brown and A. Romanov, “Contravariant pairings between standard Whittaker
modules and Verma modules,” Journal of Algebra, vol. 609, no. 11. Elsevier,
pp. 145–179, 2022.
ista: Brown A, Romanov A. 2022. Contravariant pairings between standard Whittaker
modules and Verma modules. Journal of Algebra. 609(11), 145–179.
mla: Brown, Adam, and Anna Romanov. “Contravariant Pairings between Standard Whittaker
Modules and Verma Modules.” Journal of Algebra, vol. 609, no. 11, Elsevier,
2022, pp. 145–79, doi:10.1016/j.jalgebra.2022.06.017.
short: A. Brown, A. Romanov, Journal of Algebra 609 (2022) 145–179.
date_created: 2022-07-08T11:40:07Z
date_published: 2022-11-01T00:00:00Z
date_updated: 2023-08-03T11:56:30Z
day: '01'
ddc:
- '510'
department:
- _id: HeEd
doi: 10.1016/j.jalgebra.2022.06.017
ec_funded: 1
external_id:
isi:
- '000861841100004'
file:
- access_level: open_access
checksum: 82abaee3d7837f703e499a9ecbb25b7c
content_type: application/pdf
creator: dernst
date_created: 2023-02-02T07:32:48Z
date_updated: 2023-02-02T07:32:48Z
file_id: '12473'
file_name: 2022_JournalAlgebra_Brown.pdf
file_size: 582962
relation: main_file
success: 1
file_date_updated: 2023-02-02T07:32:48Z
has_accepted_license: '1'
intvolume: ' 609'
isi: 1
issue: '11'
keyword:
- Algebra and Number Theory
language:
- iso: eng
month: '11'
oa: 1
oa_version: Published Version
page: 145-179
project:
- _id: 260C2330-B435-11E9-9278-68D0E5697425
call_identifier: H2020
grant_number: '754411'
name: ISTplus - Postdoctoral Fellowships
publication: Journal of Algebra
publication_identifier:
issn:
- 0021-8693
publication_status: published
publisher: Elsevier
quality_controlled: '1'
scopus_import: '1'
status: public
title: Contravariant pairings between standard Whittaker modules and Verma modules
tmp:
image: /images/cc_by.png
legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
short: CC BY (4.0)
type: journal_article
user_id: 4359f0d1-fa6c-11eb-b949-802e58b17ae8
volume: 609
year: '2022'
...
---
_id: '10754'
abstract:
- lang: eng
text: Targeting dysregulated Ca2+ signaling in cancer cells is an emerging chemotherapy
approach. We previously reported that store-operated Ca2+ entry (SOCE) blockers,
such as RP4010, are promising antitumor drugs for esophageal cancer. As a tyrosine
kinase inhibitor (TKI), afatinib received FDA approval to be used in targeted
therapy for patients with EGFR mutation-positive cancers. While preclinical studies
and clinical trials have shown that afatinib has benefits for esophageal cancer
patients, it is not known whether a combination of afatinib and RP4010 could achieve
better anticancer effects. Since TKI can alter intracellular Ca2+ dynamics through
EGFR/phospholipase C-γ pathway, in this study, we evaluated the inhibitory effect
of afatinib and RP4010 on intracellular Ca2+ oscillations in KYSE-150, a human
esophageal squamous cell carcinoma cell line, using both experimental and mathematical
simulations. Our mathematical simulation of Ca2+ oscillations could fit well with
experimental data responding to afatinib or RP4010, both separately or in combination.
Guided by simulation, we were able to identify a proper ratio of afatinib and
RP4010 for combined treatment, and such a combination presented synergistic anticancer-effect
evidence by experimental measurement of intracellular Ca2+ and cell proliferation.
This intracellular Ca2+ dynamic-based mathematical simulation approach could be
useful for a rapid and cost-effective evaluation of combined targeting therapy
drugs.
acknowledgement: "This work was partially supported by grants from National Institutes
of Health (NIH) (R01 CA185055, S10OD0252300) and The University of Texas System
STARs Award (to Z.P.),\r\nThe University of Texas at Arlington Interdisciplinary
Research Program (to B.C., H.V.K. and Z.P.). "
article_number: '1763'
article_processing_charge: Yes
article_type: original
author:
- first_name: Yan
full_name: Chang, Yan
last_name: Chang
- first_name: Marah
full_name: Funk, Marah
last_name: Funk
- first_name: Souvik
full_name: Roy, Souvik
last_name: Roy
- first_name: Elizabeth R
full_name: Stephenson, Elizabeth R
id: 2D04F932-F248-11E8-B48F-1D18A9856A87
last_name: Stephenson
orcid: 0000-0002-6862-208X
- first_name: Sangyong
full_name: Choi, Sangyong
last_name: Choi
- first_name: Hristo V.
full_name: Kojouharov, Hristo V.
last_name: Kojouharov
- first_name: Benito
full_name: Chen, Benito
last_name: Chen
- first_name: Zui
full_name: Pan, Zui
last_name: Pan
citation:
ama: Chang Y, Funk M, Roy S, et al. Developing a mathematical model of intracellular
Calcium dynamics for evaluating combined anticancer effects of afatinib and RP4010
in esophageal cancer. International Journal of Molecular Sciences. 2022;23(3).
doi:10.3390/ijms23031763
apa: Chang, Y., Funk, M., Roy, S., Stephenson, E. R., Choi, S., Kojouharov, H. V.,
… Pan, Z. (2022). Developing a mathematical model of intracellular Calcium dynamics
for evaluating combined anticancer effects of afatinib and RP4010 in esophageal
cancer. International Journal of Molecular Sciences. MDPI. https://doi.org/10.3390/ijms23031763
chicago: Chang, Yan, Marah Funk, Souvik Roy, Elizabeth R Stephenson, Sangyong Choi,
Hristo V. Kojouharov, Benito Chen, and Zui Pan. “Developing a Mathematical Model
of Intracellular Calcium Dynamics for Evaluating Combined Anticancer Effects of
Afatinib and RP4010 in Esophageal Cancer.” International Journal of Molecular
Sciences. MDPI, 2022. https://doi.org/10.3390/ijms23031763.
ieee: Y. Chang et al., “Developing a mathematical model of intracellular
Calcium dynamics for evaluating combined anticancer effects of afatinib and RP4010
in esophageal cancer,” International Journal of Molecular Sciences, vol.
23, no. 3. MDPI, 2022.
ista: Chang Y, Funk M, Roy S, Stephenson ER, Choi S, Kojouharov HV, Chen B, Pan
Z. 2022. Developing a mathematical model of intracellular Calcium dynamics for
evaluating combined anticancer effects of afatinib and RP4010 in esophageal cancer.
International Journal of Molecular Sciences. 23(3), 1763.
mla: Chang, Yan, et al. “Developing a Mathematical Model of Intracellular Calcium
Dynamics for Evaluating Combined Anticancer Effects of Afatinib and RP4010 in
Esophageal Cancer.” International Journal of Molecular Sciences, vol. 23,
no. 3, 1763, MDPI, 2022, doi:10.3390/ijms23031763.
short: Y. Chang, M. Funk, S. Roy, E.R. Stephenson, S. Choi, H.V. Kojouharov, B.
Chen, Z. Pan, International Journal of Molecular Sciences 23 (2022).
date_created: 2022-02-13T23:01:35Z
date_published: 2022-02-01T00:00:00Z
date_updated: 2023-08-09T10:17:07Z
day: '01'
ddc:
- '510'
- '576'
department:
- _id: HeEd
doi: 10.3390/ijms23031763
external_id:
isi:
- '000754773500001'
file:
- access_level: open_access
checksum: 8890ad20c54e90dc58ad5ea97c902998
content_type: application/pdf
creator: dernst
date_created: 2022-02-14T07:46:30Z
date_updated: 2022-02-14T07:46:30Z
file_id: '10756'
file_name: 2022_IJMS_Chang.pdf
file_size: 24416183
relation: main_file
success: 1
file_date_updated: 2022-02-14T07:46:30Z
has_accepted_license: '1'
intvolume: ' 23'
isi: 1
issue: '3'
language:
- iso: eng
month: '02'
oa: 1
oa_version: Published Version
publication: International Journal of Molecular Sciences
publication_identifier:
eissn:
- '14220067'
issn:
- '16616596'
publication_status: published
publisher: MDPI
quality_controlled: '1'
scopus_import: '1'
status: public
title: Developing a mathematical model of intracellular Calcium dynamics for evaluating
combined anticancer effects of afatinib and RP4010 in esophageal cancer
tmp:
image: /images/cc_by.png
legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
short: CC BY (4.0)
type: journal_article
user_id: 3E5EF7F0-F248-11E8-B48F-1D18A9856A87
volume: 23
year: '2022'
...