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29 Publications

2019 | Journal Article | IST-REx-ID: 6025   OA
Capek D, Smutny M, Tichy AM, Morri M, Janovjak HL, Heisenberg C-PJ. 2019. Light-activated Frizzled7 reveals a permissive role of non-canonical wnt signaling in mesendoderm cell migration. eLife. 8.
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2019 | Journal Article | IST-REx-ID: 6564   OA
Tichy A-M, Gerrard EJ, Legrand JMD, Hobbs RM, Janovjak HL. 2019. Engineering strategy and vector library for the rapid generation of modular light-controlled protein–protein interactions. Journal of Molecular Biology.
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2019 | Thesis | IST-REx-ID: 7132   OA
Mckenzie C. 2019. Design and characterization of methods and biological components to realize synthetic neurotransmission, IST Austria, 95p.
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2018 | Journal Article | IST-REx-ID: 137   OA
Zhang W, Herde M, Mitchell J, Whitfield J, Wulff A, Vongsouthi V, Sanchez Romero I, Gulakova P, Minge D, Breithausen B, Schoch S, Janovjak HL, Jackson C, Henneberger C. 2018. Monitoring hippocampal glycine with the computationally designed optical sensor GlyFS. Nature Chemical Biology. 14(9), 861–869.
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2018 | Thesis | IST-REx-ID: 418   OA
Gschaider-Reichhart E. 2018. Optical and optogenetic control of proliferation and survival , IST Austria, 107p.
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2018 | Journal Article | IST-REx-ID: 5984   OA
Morri M, Sanchez-Romero I, Tichy A-M, Kainrath S, Gerrard EJ, Hirschfeld P, Schwarz J, Janovjak HL. 2018. Optical functionalization of human class A orphan G-protein-coupled receptors. Nature Communications. 9(1).
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2018 | Thesis | IST-REx-ID: 6266
Mckenzie C. 2018. Design and characterization of methods and biological components to realize synthetic neurotransmission , IST Austria, 95p.
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2017 | Book Chapter | IST-REx-ID: 958
Mitchell J, Zhang W, Herde M, Henneberger C, Janovjak HL, O’Mara M, Jackson C. 2017. Method for developing optical sensors using a synthetic dye fluorescent protein FRET pair and computational modeling and assessment. Synthetic Protein Switches. Synthetic Protein Switches, Methods in Molecular Biology, vol. 1596. 89–99.
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2017 | Journal Article | IST-REx-ID: 1028
Kainrath S, Stadler M, Gschaider-Reichhart E, Distel M, Janovjak HL. 2017. Green-light-induced inactivation of receptor signaling using cobalamin-binding domains. Angewandte Chemie - International Edition. 56(16), 4608–4611.
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2017 | Journal Article | IST-REx-ID: 538   OA
Kainrath S, Stadler M, Gschaider-Reichhart E, Distel M, Janovjak HL. 2017. Grünlicht-induzierte Rezeptorinaktivierung durch Cobalamin-bindende Domänen. Angewandte Chemie. 129(16), 4679–4682.
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2017 | Journal Article | IST-REx-ID: 1026
Agus V, Janovjak HL. 2017. Optogenetic methods in drug screening: Technologies and applications. Current Opinion in Biotechnology. 48, 8–14.
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2017 | Book Chapter | IST-REx-ID: 957
Clifton B, Whitfield J, Sanchez Romero I, Herde M, Henneberger C, Janovjak HL, Jackson C. 2017. Ancestral protein reconstruction and circular permutation for improving the stability and dynamic range of FRET sensors. Synthetic Protein Switches. Synthetic Protein Switches, Methods in Molecular Biology, vol. 1596. 71–87.
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2016 | Journal Article | IST-REx-ID: 1440
Janovjak HL. 2016. Light at the end of the protein: Crystal structure of a C-terminal light-sensing domain. Structure. 24(2), 213–215.
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2016 | Thesis | IST-REx-ID: 1124
Morri M. 2016. Optical functionalization of human class A orphan G-protein coupled receptors, IST Austria, 129p.
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2016 | Journal Article | IST-REx-ID: 1441
Gschaider-Reichhart E, Inglés Prieto Á, Tichy A-M, Mckenzie C, Janovjak HL. 2016. A phytochrome sensory domain permits receptor activation by red light. Angewandte Chemie - International Edition. 55(21), 6339–6342.
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2016 | Journal Article | IST-REx-ID: 1100
Sako K, Pradhan S, Barone V, Inglés Prieto Á, Mueller P, Ruprecht V, Capek D, Galande S, Janovjak HL, Heisenberg C-PJ. 2016. Optogenetic control of nodal signaling reveals a temporal pattern of nodal signaling regulating cell fate specification during gastrulation. Cell Reports. 16(3), 866–877.
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2016 | Journal Article | IST-REx-ID: 1101
Mitchell J, Whitfield J, Zhang W, Henneberger C, Janovjak HL, O’Mara M, Jackson C. 2016. Rangefinder: A semisynthetic FRET sensor design algorithm. ACS SENSORS. 1(11), 1286–1290.
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2015 | Journal Article | IST-REx-ID: 1611   OA
Whitfield J, Zhang W, Herde M, Clifton B, Radziejewski J, Janovjak HL, Henneberger C, Jackson C. 2015. Construction of a robust and sensitive arginine biosensor through ancestral protein reconstruction. Protein Science. 24(9), 1412–1422.
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2015 | Journal Article | IST-REx-ID: 1678
Inglés Prieto Á, Gschaider-Reichhart E, Muellner M, Nowak M, Nijman S, Grusch M, Janovjak HL. 2015. Light-assisted small-molecule screening against protein kinases. Nature Chemical Biology. 11(12), 952–954.
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2015 | Book Chapter | IST-REx-ID: 1549   OA
Mckenzie C, Sanchez Romero I, Janovjak HL. 2015. Flipping the photoswitch: Ion channels under light control. Novel chemical tools to study ion channel biology. Advances in Experimental Medicine and Biology vol. 869. 101–117.
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2015 | Journal Article | IST-REx-ID: 1867
Hühner J, Inglés Prieto Á, Neusüß C, Lämmerhofer M, Janovjak HL. 2015. Quantification of riboflavin, flavin mononucleotide, and flavin adenine dinucleotide in mammalian model cells by CE with LED-induced fluorescence detection. Electrophoresis. 36(4), 518–525.
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2014 | Journal Article | IST-REx-ID: 1844   OA
Risso V, Manssour Triedo F, Delgado Delgado A, Arco R, Barroso Deljesús A, Inglés Prieto Á, Godoy Ruiz R, Gavira J, Gaucher E, Ibarra Molero B, Sánchez Ruiz J. 2014. Mutational studies on resurrected ancestral proteins reveal conservation of site-specific amino acid preferences throughout evolutionary history. Molecular Biology and Evolution. 32(2), 440–455.
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2014 | Journal Article | IST-REx-ID: 2032   OA
Inglés Prieto Á, Gschaider-Reichhart E, Schelch K, Janovjak HL, Grusch M. 2014. The optogenetic promise for oncology: Episode I. Molecular and Cellular Oncology. 1(4), e964045.
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2014 | Journal Article | IST-REx-ID: 2084
Grusch M, Schelch K, Riedler R, Gschaider-Reichhart E, Differ C, Berger W, Inglés Prieto Á, Janovjak HL. 2014. Spatio-temporally precise activation of engineered receptor tyrosine kinases by light. EMBO Journal. 33(15), 1713–1726.
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2013 | Journal Article | IST-REx-ID: 505
Greimel K, Perz V, Koren K, Feola R, Temel A, Sohar C, Herrero Acero E, Klimant I, Guebitz G. 2013. Banning toxic heavy-metal catalysts from paints: Enzymatic cross-linking of alkyd resins. Green Chemistry. 15(2), 381–388.
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2013 | Journal Article | IST-REx-ID: 2471   OA
Sanchez Romero I, Ariza A, Wilson K, Skjøt M, Vind J, De Maria L, Skov L, Sánchez Ruiz J. 2013. Mechanism of protein kinetic stabilization by engineered disulfide crosslinks. PLoS One. 8(7).
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2013 | Journal Article | IST-REx-ID: 2856   OA
Levitz J, Pantoja C, Gaub B, Janovjak HL, Reiner A, Hoagland A, Schoppik D, Kane B, Stawski P, Schier A, Trauner D, Isacoff E. 2013. Optical control of metabotropic glutamate receptors. Nature Neuroscience. 16, 507–516.
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2013 | Journal Article | IST-REx-ID: 2857   OA
Szobota S, Mckenzie C, Janovjak HL. 2013. Optical control of ligand-gated ion channels. Methods in Molecular Biology. 998, 417–435.
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2011 | Journal Article | IST-REx-ID: 3405   OA
Janovjak HL, Sandoz G, Isacoff E. 2011. Modern ionotropic glutamate receptor with a K+ selectivity signature sequence. Nature Communications. 2(232), 1–6.
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