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29 Publications

2019 | Journal Article | IST-REx-ID: 6025   OA
D. Capek, M. Smutny, A. M. Tichy, M. Morri, H. L. Janovjak, and C.-P. J. Heisenberg, “Light-activated Frizzled7 reveals a permissive role of non-canonical wnt signaling in mesendoderm cell migration,” eLife, vol. 8, 2019.
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2019 | Journal Article | IST-REx-ID: 6564   OA
A.-M. Tichy, E. J. Gerrard, J. M. D. Legrand, R. M. Hobbs, and H. L. Janovjak, “Engineering strategy and vector library for the rapid generation of modular light-controlled protein–protein interactions,” Journal of Molecular Biology, 2019.
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2019 | Thesis | IST-REx-ID: 7132   OA
C. Mckenzie, Design and characterization of methods and biological components to realize synthetic neurotransmission. IST Austria, 2019.
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2018 | Journal Article | IST-REx-ID: 137   OA
W. Zhang et al., “Monitoring hippocampal glycine with the computationally designed optical sensor GlyFS,” Nature Chemical Biology, vol. 14, no. 9, pp. 861–869, 2018.
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2018 | Thesis | IST-REx-ID: 418   OA
E. Gschaider-Reichhart, Optical and optogenetic control of proliferation and survival . IST Austria, 2018.
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2018 | Journal Article | IST-REx-ID: 5984   OA
M. Morri et al., “Optical functionalization of human class A orphan G-protein-coupled receptors,” Nature Communications, vol. 9, no. 1, 2018.
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2018 | Thesis | IST-REx-ID: 6266
C. Mckenzie, Design and characterization of methods and biological components to realize synthetic neurotransmission . IST Austria, 2018.
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2017 | Book Chapter | IST-REx-ID: 958
J. Mitchell et al., “Method for developing optical sensors using a synthetic dye fluorescent protein FRET pair and computational modeling and assessment,” in Synthetic Protein Switches, vol. 1596, V. Stein, Ed. Springer, 2017, pp. 89–99.
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2017 | Journal Article | IST-REx-ID: 1028
S. Kainrath, M. Stadler, E. Gschaider-Reichhart, M. Distel, and H. L. Janovjak, “Green-light-induced inactivation of receptor signaling using cobalamin-binding domains,” Angewandte Chemie - International Edition, vol. 56, no. 16, pp. 4608–4611, 2017.
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2017 | Journal Article | IST-REx-ID: 538   OA
S. Kainrath, M. Stadler, E. Gschaider-Reichhart, M. Distel, and H. L. Janovjak, “Grünlicht-induzierte Rezeptorinaktivierung durch Cobalamin-bindende Domänen,” Angewandte Chemie, vol. 129, no. 16, pp. 4679–4682, 2017.
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2017 | Journal Article | IST-REx-ID: 1026
V. Agus and H. L. Janovjak, “Optogenetic methods in drug screening: Technologies and applications,” Current Opinion in Biotechnology, vol. 48, pp. 8–14, 2017.
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2017 | Book Chapter | IST-REx-ID: 957
B. Clifton et al., “Ancestral protein reconstruction and circular permutation for improving the stability and dynamic range of FRET sensors,” in Synthetic Protein Switches, vol. 1596, V. Stein, Ed. Springer, 2017, pp. 71–87.
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2016 | Journal Article | IST-REx-ID: 1440
H. L. Janovjak, “Light at the end of the protein: Crystal structure of a C-terminal light-sensing domain,” Structure, vol. 24, no. 2, pp. 213–215, 2016.
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2016 | Thesis | IST-REx-ID: 1124
M. Morri, Optical functionalization of human class A orphan G-protein coupled receptors. IST Austria, 2016.
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2016 | Journal Article | IST-REx-ID: 1441
E. Gschaider-Reichhart, Á. Inglés Prieto, A.-M. Tichy, C. Mckenzie, and H. L. Janovjak, “A phytochrome sensory domain permits receptor activation by red light,” Angewandte Chemie - International Edition, vol. 55, no. 21, pp. 6339–6342, 2016.
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2016 | Journal Article | IST-REx-ID: 1100
K. Sako et al., “Optogenetic control of nodal signaling reveals a temporal pattern of nodal signaling regulating cell fate specification during gastrulation,” Cell Reports, vol. 16, no. 3, pp. 866–877, 2016.
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2016 | Journal Article | IST-REx-ID: 1101
J. Mitchell et al., “Rangefinder: A semisynthetic FRET sensor design algorithm,” ACS SENSORS, vol. 1, no. 11, pp. 1286–1290, 2016.
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2015 | Journal Article | IST-REx-ID: 1611   OA
J. Whitfield et al., “Construction of a robust and sensitive arginine biosensor through ancestral protein reconstruction,” Protein Science, vol. 24, no. 9, pp. 1412–1422, 2015.
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2015 | Journal Article | IST-REx-ID: 1678
Á. Inglés Prieto et al., “Light-assisted small-molecule screening against protein kinases,” Nature Chemical Biology, vol. 11, no. 12, pp. 952–954, 2015.
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2015 | Book Chapter | IST-REx-ID: 1549   OA
C. Mckenzie, I. Sanchez Romero, and H. L. Janovjak, “Flipping the photoswitch: Ion channels under light control,” in Novel chemical tools to study ion channel biology, vol. 869, Springer, 2015, pp. 101–117.
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2015 | Journal Article | IST-REx-ID: 1867
J. Hühner, Á. Inglés Prieto, C. Neusüß, M. Lämmerhofer, and H. L. Janovjak, “Quantification of riboflavin, flavin mononucleotide, and flavin adenine dinucleotide in mammalian model cells by CE with LED-induced fluorescence detection,” Electrophoresis, vol. 36, no. 4, pp. 518–525, 2015.
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2014 | Journal Article | IST-REx-ID: 1844   OA
V. Risso et al., “Mutational studies on resurrected ancestral proteins reveal conservation of site-specific amino acid preferences throughout evolutionary history,” Molecular Biology and Evolution, vol. 32, no. 2, pp. 440–455, 2014.
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2014 | Journal Article | IST-REx-ID: 2032   OA
Á. Inglés Prieto, E. Gschaider-Reichhart, K. Schelch, H. L. Janovjak, and M. Grusch, “The optogenetic promise for oncology: Episode I,” Molecular and Cellular Oncology, vol. 1, no. 4, p. e964045, 2014.
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2014 | Journal Article | IST-REx-ID: 2084
M. Grusch et al., “Spatio-temporally precise activation of engineered receptor tyrosine kinases by light,” EMBO Journal, vol. 33, no. 15, pp. 1713–1726, 2014.
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2013 | Journal Article | IST-REx-ID: 505
K. Greimel et al., “Banning toxic heavy-metal catalysts from paints: Enzymatic cross-linking of alkyd resins,” Green Chemistry, vol. 15, no. 2, pp. 381–388, 2013.
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2013 | Journal Article | IST-REx-ID: 2471   OA
I. Sanchez Romero et al., “Mechanism of protein kinetic stabilization by engineered disulfide crosslinks,” PLoS One, vol. 8, no. 7, 2013.
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2013 | Journal Article | IST-REx-ID: 2856   OA
J. Levitz et al., “Optical control of metabotropic glutamate receptors,” Nature Neuroscience, vol. 16, pp. 507–516, 2013.
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2013 | Journal Article | IST-REx-ID: 2857   OA
S. Szobota, C. Mckenzie, and H. L. Janovjak, “Optical control of ligand-gated ion channels,” Methods in Molecular Biology, vol. 998, pp. 417–435, 2013.
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2011 | Journal Article | IST-REx-ID: 3405   OA
H. L. Janovjak, G. Sandoz, and E. Isacoff, “Modern ionotropic glutamate receptor with a K+ selectivity signature sequence,” Nature Communications, vol. 2, no. 232, pp. 1–6, 2011.
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