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31 Publications

2020 | Journal Article | IST-REx-ID: 8674
Henneberger, Christian, Lucie Bard, Aude Panatier, James P. Reynolds, Olga Kopach, Nikolay I. Medvedev, Daniel Minge, et al. “LTP Induction Boosts Glutamate Spillover by Driving Withdrawal of Perisynaptic Astroglia.” Neuron, n.d. https://doi.org/10.1016/j.neuron.2020.08.030.
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2019 | Thesis | IST-REx-ID: 7132 | OA
Mckenzie, Catherine. Design and Characterization of Methods and Biological Components to Realize Synthetic Neurotransmission. IST Austria, 2019. https://doi.org/10.15479/at:ista:7132.
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2019 | Journal Article | IST-REx-ID: 7406
Mckenzie, Catherine, Miroslava Spanova, Alexander J Johnson, Stephanie Kainrath, Vanessa Zheden, Harald H. Sitte, and Harald L Janovjak. “Isolation of Synaptic Vesicles from Genetically Engineered Cultured Neurons.” Journal of Neuroscience Methods 312 (2019): 114–21. https://doi.org/10.1016/j.jneumeth.2018.11.018.
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2019 | Journal Article | IST-REx-ID: 6025 | OA
Capek, Daniel, Michael Smutny, Alexandra Madelaine Tichy, Maurizio Morri, Harald L Janovjak, and Carl-Philipp J Heisenberg. “Light-Activated Frizzled7 Reveals a Permissive Role of Non-Canonical Wnt Signaling in Mesendoderm Cell Migration.” ELife 8 (2019). https://doi.org/10.7554/eLife.42093.
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2019 | Journal Article | IST-REx-ID: 6564 | OA
Tichy, Alexandra-Madelaine, Elliot J. Gerrard, Julien M.D. Legrand, Robin M. Hobbs, and Harald L Janovjak. “Engineering Strategy and Vector Library for the Rapid Generation of Modular Light-Controlled Protein–Protein Interactions.” Journal of Molecular Biology 431, no. 17 (2019): 3046–55. https://doi.org/10.1016/j.jmb.2019.05.033.
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2018 | Thesis | IST-REx-ID: 418 | OA
Gschaider-Reichhart, Eva. Optical and Optogenetic Control of Proliferation and Survival . IST Austria, 2018. https://doi.org/10.15479/AT:ISTA:th_913.
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2018 | Journal Article | IST-REx-ID: 5984 | OA
Morri, Maurizio, Inmaculada Sanchez-Romero, Alexandra-Madelaine Tichy, Stephanie Kainrath, Elliot J. Gerrard, Priscila Hirschfeld, Jan Schwarz, and Harald L Janovjak. “Optical Functionalization of Human Class A Orphan G-Protein-Coupled Receptors.” Nature Communications 9, no. 1 (2018). https://doi.org/10.1038/s41467-018-04342-1.
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2018 | Thesis | IST-REx-ID: 6266 | OA
Mckenzie, Catherine. Design and Characterization of Methods and Biological Components to Realize Synthetic Neurotransmission . IST Austria, 2018. https://doi.org/10.15479/at:ista:th_1055.
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2018 | Journal Article | IST-REx-ID: 137 | OA
Zhang, William, Michel Herde, Joshua Mitchell, Jason Whitfield, Andreas Wulff, Vanessa Vongsouthi, Inmaculada Sanchez Romero, et al. “Monitoring Hippocampal Glycine with the Computationally Designed Optical Sensor GlyFS.” Nature Chemical Biology 14, no. 9 (2018): 861–69. https://doi.org/10.1038/s41589-018-0108-2.
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2017 | Journal Article | IST-REx-ID: 538 | OA
Kainrath, Stephanie, Manuela Stadler, Eva Gschaider-Reichhart, Martin Distel, and Harald L Janovjak. “Grünlicht-Induzierte Rezeptorinaktivierung Durch Cobalamin-Bindende Domänen.” Angewandte Chemie 129, no. 16 (2017): 4679–82. https://doi.org/10.1002/ange.201611998.
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2017 | Book Chapter | IST-REx-ID: 957
Clifton, Ben, Jason Whitfield, Inmaculada Sanchez Romero, Michel Herde, Christian Henneberger, Harald L Janovjak, and Colin Jackson. “Ancestral Protein Reconstruction and Circular Permutation for Improving the Stability and Dynamic Range of FRET Sensors.” In Synthetic Protein Switches, edited by Viktor Stein, 1596:71–87. Synthetic Protein Switches. Springer, 2017. https://doi.org/10.1007/978-1-4939-6940-1_5.
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2017 | Book Chapter | IST-REx-ID: 958
Mitchell, Joshua, William Zhang, Michel Herde, Christian Henneberger, Harald L Janovjak, Megan O’Mara, and Colin Jackson. “Method for Developing Optical Sensors Using a Synthetic Dye Fluorescent Protein FRET Pair and Computational Modeling and Assessment.” In Synthetic Protein Switches, edited by Viktor Stein, 1596:89–99. Synthetic Protein Switches. Springer, 2017. https://doi.org/10.1007/978-1-4939-6940-1_6.
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2017 | Journal Article | IST-REx-ID: 1026
Agus, Viviana, and Harald L Janovjak. “Optogenetic Methods in Drug Screening: Technologies and Applications.” Current Opinion in Biotechnology 48 (2017): 8–14. https://doi.org/10.1016/j.copbio.2017.02.006.
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2017 | Journal Article | IST-REx-ID: 1028 | OA
Kainrath, Stephanie, Manuela Stadler, Eva Gschaider-Reichhart, Martin Distel, and Harald L Janovjak. “Green-Light-Induced Inactivation of Receptor Signaling Using Cobalamin-Binding Domains.” Angewandte Chemie - International Edition 56, no. 16 (2017): 4608–11. https://doi.org/10.1002/anie.201611998.
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2016 | Journal Article | IST-REx-ID: 1440
Janovjak, Harald L. “Light at the End of the Protein: Crystal Structure of a C-Terminal Light-Sensing Domain.” Structure 24, no. 2 (2016): 213–15. https://doi.org/10.1016/j.str.2016.01.002.
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2016 | Journal Article | IST-REx-ID: 1441 | OA
Gschaider-Reichhart, Eva, Álvaro Inglés Prieto, Alexandra-Madelaine Tichy, Catherine Mckenzie, and Harald L Janovjak. “A Phytochrome Sensory Domain Permits Receptor Activation by Red Light.” Angewandte Chemie - International Edition 55, no. 21 (2016): 6339–42. https://doi.org/10.1002/anie.201601736.
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2016 | Journal Article | IST-REx-ID: 1100 | OA
Sako, Keisuke, Saurabh Pradhan, Vanessa Barone, Álvaro Inglés Prieto, Patrick Mueller, Verena Ruprecht, Daniel Capek, Sanjeev Galande, Harald L Janovjak, and Carl-Philipp J Heisenberg. “Optogenetic Control of Nodal Signaling Reveals a Temporal Pattern of Nodal Signaling Regulating Cell Fate Specification during Gastrulation.” Cell Reports 16, no. 3 (2016): 866–77. https://doi.org/10.1016/j.celrep.2016.06.036.
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2016 | Journal Article | IST-REx-ID: 1101
Mitchell, Joshua, Jason Whitfield, William Zhang, Christian Henneberger, Harald L Janovjak, Megan O’Mara, and Colin Jackson. “Rangefinder: A Semisynthetic FRET Sensor Design Algorithm.” ACS SENSORS 1, no. 11 (2016): 1286–90. https://doi.org/10.1021/acssensors.6b00576.
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2016 | Thesis | IST-REx-ID: 1124
Morri, Maurizio. Optical Functionalization of Human Class A Orphan G-Protein Coupled Receptors. IST Austria, 2016.
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2015 | Book Chapter | IST-REx-ID: 1549 | OA
Mckenzie, Catherine, Inmaculada Sanchez-Romero, and Harald L Janovjak. “Flipping the Photoswitch: Ion Channels under Light Control.” In Novel Chemical Tools to Study Ion Channel Biology, 869:101–17. Advances in Experimental Medicine and Biology. Springer, 2015. https://doi.org/10.1007/978-1-4939-2845-3_6.
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2015 | Journal Article | IST-REx-ID: 1611 | OA
Whitfield, Jason, William Zhang, Michel Herde, Ben Clifton, Johanna Radziejewski, Harald L Janovjak, Christian Henneberger, and Colin Jackson. “Construction of a Robust and Sensitive Arginine Biosensor through Ancestral Protein Reconstruction.” Protein Science 24, no. 9 (2015): 1412–22. https://doi.org/10.1002/pro.2721.
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2015 | Journal Article | IST-REx-ID: 1678 | OA
Inglés Prieto, Álvaro, Eva Gschaider-Reichhart, Markus Muellner, Matthias Nowak, Sebastian Nijman, Michael Grusch, and Harald L Janovjak. “Light-Assisted Small-Molecule Screening against Protein Kinases.” Nature Chemical Biology 11, no. 12 (2015): 952–54. https://doi.org/10.1038/nchembio.1933.
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2015 | Journal Article | IST-REx-ID: 1867
Hühner, Jens, Álvaro Inglés Prieto, Christian Neusüß, Michael Lämmerhofer, and Harald L Janovjak. “Quantification of Riboflavin, Flavin Mononucleotide, and Flavin Adenine Dinucleotide in Mammalian Model Cells by CE with LED-Induced Fluorescence Detection.” Electrophoresis 36, no. 4 (2015): 518–25. https://doi.org/10.1002/elps.201400451.
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2014 | Journal Article | IST-REx-ID: 2032 | OA
Inglés Prieto, Álvaro, Eva Gschaider-Reichhart, Karin Schelch, Harald L Janovjak, and Michael Grusch. “The Optogenetic Promise for Oncology: Episode I.” Molecular and Cellular Oncology 1, no. 4 (2014). https://doi.org/10.4161/23723548.2014.964045.
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2014 | Journal Article | IST-REx-ID: 2084 | OA
Grusch, Michael, Karin Schelch, Robert Riedler, Eva Gschaider-Reichhart, Christopher Differ, Walter Berger, Álvaro Inglés Prieto, and Harald L Janovjak. “Spatio-Temporally Precise Activation of Engineered Receptor Tyrosine Kinases by Light.” EMBO Journal 33, no. 15 (2014): 1713–26. https://doi.org/10.15252/embj.201387695.
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2014 | Journal Article | IST-REx-ID: 1844 | OA
Risso, Valeria, Fadia Manssour Triedo, Asuncion Delgado Delgado, Rocio Arco, Alicia Barroso Deljesús, Álvaro Inglés Prieto, Raquel Godoy Ruiz, et al. “Mutational Studies on Resurrected Ancestral Proteins Reveal Conservation of Site-Specific Amino Acid Preferences throughout Evolutionary History.” Molecular Biology and Evolution 32, no. 2 (2014): 440–55. https://doi.org/10.1093/molbev/msu312.
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2013 | Journal Article | IST-REx-ID: 2471 | OA
Sanchez-Romero, Inmaculada, Antonio Ariza, Keith Wilson, Michael Skjøt, Jesper Vind, Leonardo De Maria, Lars Skov, and Jose Sánchez Ruiz. “Mechanism of Protein Kinetic Stabilization by Engineered Disulfide Crosslinks.” PLoS One 8, no. 7 (2013). https://doi.org/10.1371/journal.pone.0070013.
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2013 | Journal Article | IST-REx-ID: 505
Greimel, Katrin, Veronika Perz, Klaus Koren, Roland Feola, Armin Temel, Christian Sohar, Enrique Herrero Acero, Ingo Klimant, and Georg Guebitz. “Banning Toxic Heavy-Metal Catalysts from Paints: Enzymatic Cross-Linking of Alkyd Resins.” Green Chemistry 15, no. 2 (2013): 381–88. https://doi.org/10.1039/c2gc36666e.
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2013 | Journal Article | IST-REx-ID: 2856 | OA
Levitz, Joshua, Carlos Pantoja, Benjamin Gaub, Harald L Janovjak, Andreas Reiner, Adam Hoagland, David Schoppik, et al. “Optical Control of Metabotropic Glutamate Receptors.” Nature Neuroscience 16 (2013): 507–16. https://doi.org/10.1038/nn.3346.
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2013 | Journal Article | IST-REx-ID: 2857 | OA
Szobota, Stephanie, Catherine Mckenzie, and Harald L Janovjak. “Optical Control of Ligand-Gated Ion Channels.” Methods in Molecular Biology 998 (2013): 417–35. https://doi.org/10.1007/978-1-62703-351-0_32.
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2011 | Journal Article | IST-REx-ID: 3405 | OA
Janovjak, Harald L, Guillaume Sandoz, and Ehud Isacoff. “Modern Ionotropic Glutamate Receptor with a K+ Selectivity Signature Sequence.” Nature Communications 2, no. 232 (2011): 1–6. https://doi.org/10.1038/ncomms1231.
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