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28 Publications
2019 | Journal Article | IST-REx-ID: 6025 
Light-activated Frizzled7 reveals a permissive role of non-canonical wnt signaling in mesendoderm cell migration
D. Capek, M. Smutny, A.M. Tichy, M. Morri, H.L. Janovjak, C.-P.J. Heisenberg, ELife 8 (2019).
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D. Capek, M. Smutny, A.M. Tichy, M. Morri, H.L. Janovjak, C.-P.J. Heisenberg, ELife 8 (2019).
2019 | Journal Article | IST-REx-ID: 6564
Engineering strategy and vector library for the rapid generation of modular light-controlled protein–protein interactions
A.-M. Tichy, E.J. Gerrard, J.M.D. Legrand, R.M. Hobbs, H.L. Janovjak, Journal of Molecular Biology (2019).
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A.-M. Tichy, E.J. Gerrard, J.M.D. Legrand, R.M. Hobbs, H.L. Janovjak, Journal of Molecular Biology (2019).
2018 | Journal Article | IST-REx-ID: 137
Monitoring hippocampal glycine with the computationally designed optical sensor GlyFS
W. Zhang, M. Herde, J. Mitchell, J. Whitfield, A. Wulff, V. Vongsouthi, I. Sanchez Romero, P. Gulakova, D. Minge, B. Breithausen, S. Schoch, H.L. Janovjak, C. Jackson, C. Henneberger, Nature Chemical Biology 14 (2018) 861–869.
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| PubMed | Europe PMC
W. Zhang, M. Herde, J. Mitchell, J. Whitfield, A. Wulff, V. Vongsouthi, I. Sanchez Romero, P. Gulakova, D. Minge, B. Breithausen, S. Schoch, H.L. Janovjak, C. Jackson, C. Henneberger, Nature Chemical Biology 14 (2018) 861–869.
2018 | Thesis | IST-REx-ID: 418
Optical and optogenetic control of proliferation and survival
E. Gschaider-Reichhart, Optical and Optogenetic Control of Proliferation and Survival , IST Austria, 2018.
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E. Gschaider-Reichhart, Optical and Optogenetic Control of Proliferation and Survival , IST Austria, 2018.
2018 | Journal Article | IST-REx-ID: 5984
Optical functionalization of human class A orphan G-protein-coupled receptors
M. Morri, I. Sanchez-Romero, A.-M. Tichy, S. Kainrath, E.J. Gerrard, P. Hirschfeld, J. Schwarz, H.L. Janovjak, Nature Communications 9 (2018).
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M. Morri, I. Sanchez-Romero, A.-M. Tichy, S. Kainrath, E.J. Gerrard, P. Hirschfeld, J. Schwarz, H.L. Janovjak, Nature Communications 9 (2018).
2018 | Thesis | IST-REx-ID: 6266
Design and characterization of methods and biological components to realize synthetic neurotransmission
C. Mckenzie, Design and Characterization of Methods and Biological Components to Realize Synthetic Neurotransmission , IST Austria, 2018.
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C. Mckenzie, Design and Characterization of Methods and Biological Components to Realize Synthetic Neurotransmission , IST Austria, 2018.
2017 | Book Chapter | IST-REx-ID: 958
Method for developing optical sensors using a synthetic dye fluorescent protein FRET pair and computational modeling and assessment
J. Mitchell, W. Zhang, M. Herde, C. Henneberger, H.L. Janovjak, M. O’Mara, C. Jackson, in:, V. Stein (Ed.), Synthetic Protein Switches, Springer, 2017, pp. 89–99.
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J. Mitchell, W. Zhang, M. Herde, C. Henneberger, H.L. Janovjak, M. O’Mara, C. Jackson, in:, V. Stein (Ed.), Synthetic Protein Switches, Springer, 2017, pp. 89–99.
2017 | Journal Article | IST-REx-ID: 1028
Green-light-induced inactivation of receptor signaling using cobalamin-binding domains
S. Kainrath, M. Stadler, E. Gschaider-Reichhart, M. Distel, H.L. Janovjak, Angewandte Chemie - International Edition 56 (2017) 4608–4611.
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S. Kainrath, M. Stadler, E. Gschaider-Reichhart, M. Distel, H.L. Janovjak, Angewandte Chemie - International Edition 56 (2017) 4608–4611.
2017 | Journal Article | IST-REx-ID: 538
Grünlicht-induzierte Rezeptorinaktivierung durch Cobalamin-bindende Domänen
S. Kainrath, M. Stadler, E. Gschaider-Reichhart, M. Distel, H.L. Janovjak, Angewandte Chemie 129 (2017) 4679–4682.
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S. Kainrath, M. Stadler, E. Gschaider-Reichhart, M. Distel, H.L. Janovjak, Angewandte Chemie 129 (2017) 4679–4682.
2017 | Journal Article | IST-REx-ID: 1026
Optogenetic methods in drug screening: Technologies and applications
V. Agus, H.L. Janovjak, Current Opinion in Biotechnology 48 (2017) 8–14.
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V. Agus, H.L. Janovjak, Current Opinion in Biotechnology 48 (2017) 8–14.
2017 | Book Chapter | IST-REx-ID: 957
Ancestral protein reconstruction and circular permutation for improving the stability and dynamic range of FRET sensors
B. Clifton, J. Whitfield, I. Sanchez Romero, M. Herde, C. Henneberger, H.L. Janovjak, C. Jackson, in:, V. Stein (Ed.), Synthetic Protein Switches, Springer, 2017, pp. 71–87.
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B. Clifton, J. Whitfield, I. Sanchez Romero, M. Herde, C. Henneberger, H.L. Janovjak, C. Jackson, in:, V. Stein (Ed.), Synthetic Protein Switches, Springer, 2017, pp. 71–87.
2016 | Journal Article | IST-REx-ID: 1440
Light at the end of the protein: Crystal structure of a C-terminal light-sensing domain
H.L. Janovjak, Structure 24 (2016) 213–215.
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H.L. Janovjak, Structure 24 (2016) 213–215.
2016 | Journal Article | IST-REx-ID: 1441
A phytochrome sensory domain permits receptor activation by red light
E. Gschaider-Reichhart, Á. Inglés Prieto, A.-M. Tichy, C. Mckenzie, H.L. Janovjak, Angewandte Chemie - International Edition 55 (2016) 6339–6342.
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E. Gschaider-Reichhart, Á. Inglés Prieto, A.-M. Tichy, C. Mckenzie, H.L. Janovjak, Angewandte Chemie - International Edition 55 (2016) 6339–6342.
2016 | Thesis | IST-REx-ID: 1124
Optical functionalization of human class A orphan G-protein coupled receptors
M. Morri, Optical Functionalization of Human Class A Orphan G-Protein Coupled Receptors, IST Austria, 2016.
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M. Morri, Optical Functionalization of Human Class A Orphan G-Protein Coupled Receptors, IST Austria, 2016.
2016 | Journal Article | IST-REx-ID: 1100
Optogenetic control of nodal signaling reveals a temporal pattern of nodal signaling regulating cell fate specification during gastrulation
K. Sako, S. Pradhan, V. Barone, Á. Inglés Prieto, P. Mueller, V. Ruprecht, D. Capek, S. Galande, H.L. Janovjak, C.-P.J. Heisenberg, Cell Reports 16 (2016) 866–877.
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K. Sako, S. Pradhan, V. Barone, Á. Inglés Prieto, P. Mueller, V. Ruprecht, D. Capek, S. Galande, H.L. Janovjak, C.-P.J. Heisenberg, Cell Reports 16 (2016) 866–877.
2016 | Journal Article | IST-REx-ID: 1101
Rangefinder: A semisynthetic FRET sensor design algorithm
J. Mitchell, J. Whitfield, W. Zhang, C. Henneberger, H.L. Janovjak, M. O’Mara, C. Jackson, ACS SENSORS 1 (2016) 1286–1290.
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J. Mitchell, J. Whitfield, W. Zhang, C. Henneberger, H.L. Janovjak, M. O’Mara, C. Jackson, ACS SENSORS 1 (2016) 1286–1290.
2015 | Journal Article | IST-REx-ID: 1611
Construction of a robust and sensitive arginine biosensor through ancestral protein reconstruction
J. Whitfield, W. Zhang, M. Herde, B. Clifton, J. Radziejewski, H.L. Janovjak, C. Henneberger, C. Jackson, Protein Science 24 (2015) 1412–1422.
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J. Whitfield, W. Zhang, M. Herde, B. Clifton, J. Radziejewski, H.L. Janovjak, C. Henneberger, C. Jackson, Protein Science 24 (2015) 1412–1422.
2015 | Journal Article | IST-REx-ID: 1678
Light-assisted small-molecule screening against protein kinases
Á. Inglés Prieto, E. Gschaider-Reichhart, M. Muellner, M. Nowak, S. Nijman, M. Grusch, H.L. Janovjak, Nature Chemical Biology 11 (2015) 952–954.
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Á. Inglés Prieto, E. Gschaider-Reichhart, M. Muellner, M. Nowak, S. Nijman, M. Grusch, H.L. Janovjak, Nature Chemical Biology 11 (2015) 952–954.
2015 | Book Chapter | IST-REx-ID: 1549
Flipping the photoswitch: Ion channels under light control
C. Mckenzie, I. Sanchez Romero, H.L. Janovjak, in:, Novel Chemical Tools to Study Ion Channel Biology, Springer, 2015, pp. 101–117.
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C. Mckenzie, I. Sanchez Romero, H.L. Janovjak, in:, Novel Chemical Tools to Study Ion Channel Biology, Springer, 2015, pp. 101–117.
2015 | Journal Article | IST-REx-ID: 1867
Quantification of riboflavin, flavin mononucleotide, and flavin adenine dinucleotide in mammalian model cells by CE with LED-induced fluorescence detection
J. Hühner, Á. Inglés Prieto, C. Neusüß, M. Lämmerhofer, H.L. Janovjak, Electrophoresis 36 (2015) 518–525.
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J. Hühner, Á. Inglés Prieto, C. Neusüß, M. Lämmerhofer, H.L. Janovjak, Electrophoresis 36 (2015) 518–525.
2014 | Journal Article | IST-REx-ID: 1844
Mutational studies on resurrected ancestral proteins reveal conservation of site-specific amino acid preferences throughout evolutionary history
V. Risso, F. Manssour Triedo, A. Delgado Delgado, R. Arco, A. Barroso Deljesús, Á. Inglés Prieto, R. Godoy Ruiz, J. Gavira, E. Gaucher, B. Ibarra Molero, J. Sánchez Ruiz, Molecular Biology and Evolution 32 (2014) 440–455.
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V. Risso, F. Manssour Triedo, A. Delgado Delgado, R. Arco, A. Barroso Deljesús, Á. Inglés Prieto, R. Godoy Ruiz, J. Gavira, E. Gaucher, B. Ibarra Molero, J. Sánchez Ruiz, Molecular Biology and Evolution 32 (2014) 440–455.
2014 | Journal Article | IST-REx-ID: 2032
The optogenetic promise for oncology: Episode I
Á. Inglés Prieto, E. Gschaider-Reichhart, K. Schelch, H.L. Janovjak, M. Grusch, Molecular and Cellular Oncology 1 (2014) e964045.
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Á. Inglés Prieto, E. Gschaider-Reichhart, K. Schelch, H.L. Janovjak, M. Grusch, Molecular and Cellular Oncology 1 (2014) e964045.
2014 | Journal Article | IST-REx-ID: 2084
Spatio-temporally precise activation of engineered receptor tyrosine kinases by light
M. Grusch, K. Schelch, R. Riedler, E. Gschaider-Reichhart, C. Differ, W. Berger, Á. Inglés Prieto, H.L. Janovjak, EMBO Journal 33 (2014) 1713–1726.
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M. Grusch, K. Schelch, R. Riedler, E. Gschaider-Reichhart, C. Differ, W. Berger, Á. Inglés Prieto, H.L. Janovjak, EMBO Journal 33 (2014) 1713–1726.
2013 | Journal Article | IST-REx-ID: 505
Banning toxic heavy-metal catalysts from paints: Enzymatic cross-linking of alkyd resins
K. Greimel, V. Perz, K. Koren, R. Feola, A. Temel, C. Sohar, E. Herrero Acero, I. Klimant, G. Guebitz, Green Chemistry 15 (2013) 381–388.
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K. Greimel, V. Perz, K. Koren, R. Feola, A. Temel, C. Sohar, E. Herrero Acero, I. Klimant, G. Guebitz, Green Chemistry 15 (2013) 381–388.
2013 | Journal Article | IST-REx-ID: 2471
Mechanism of protein kinetic stabilization by engineered disulfide crosslinks
I. Sanchez Romero, A. Ariza, K. Wilson, M. Skjøt, J. Vind, L. De Maria, L. Skov, J. Sánchez Ruiz, PLoS One 8 (2013).
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I. Sanchez Romero, A. Ariza, K. Wilson, M. Skjøt, J. Vind, L. De Maria, L. Skov, J. Sánchez Ruiz, PLoS One 8 (2013).
2013 | Journal Article | IST-REx-ID: 2856
Optical control of metabotropic glutamate receptors
J. Levitz, C. Pantoja, B. Gaub, H.L. Janovjak, A. Reiner, A. Hoagland, D. Schoppik, B. Kane, P. Stawski, A. Schier, D. Trauner, E. Isacoff, Nature Neuroscience 16 (2013) 507–516.
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J. Levitz, C. Pantoja, B. Gaub, H.L. Janovjak, A. Reiner, A. Hoagland, D. Schoppik, B. Kane, P. Stawski, A. Schier, D. Trauner, E. Isacoff, Nature Neuroscience 16 (2013) 507–516.
2013 | Journal Article | IST-REx-ID: 2857
Optical control of ligand-gated ion channels
S. Szobota, C. Mckenzie, H.L. Janovjak, Methods in Molecular Biology 998 (2013) 417–435.
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S. Szobota, C. Mckenzie, H.L. Janovjak, Methods in Molecular Biology 998 (2013) 417–435.
2011 | Journal Article | IST-REx-ID: 3405
Modern ionotropic glutamate receptor with a K+ selectivity signature sequence
H.L. Janovjak, G. Sandoz, E. Isacoff, Nature Communications 2 (2011) 1–6.
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H.L. Janovjak, G. Sandoz, E. Isacoff, Nature Communications 2 (2011) 1–6.