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28 Publications

2019 | Journal Article | IST-REx-ID: 6025   OA
Capek, D., Smutny, M., Tichy, A. M., Morri, M., Janovjak, H. L., & Heisenberg, C.-P. J. (2019). Light-activated Frizzled7 reveals a permissive role of non-canonical wnt signaling in mesendoderm cell migration. ELife, 8. https://doi.org/10.7554/eLife.42093
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2019 | Journal Article | IST-REx-ID: 6564   OA
Tichy, A.-M., Gerrard, E. J., Legrand, J. M. D., Hobbs, R. M., & Janovjak, H. L. (2019). Engineering strategy and vector library for the rapid generation of modular light-controlled protein–protein interactions. Journal of Molecular Biology. https://doi.org/10.1016/j.jmb.2019.05.033
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2018 | Journal Article | IST-REx-ID: 137   OA
Zhang, W., Herde, M., Mitchell, J., Whitfield, J., Wulff, A., Vongsouthi, V., … Henneberger, C. (2018). Monitoring hippocampal glycine with the computationally designed optical sensor GlyFS. Nature Chemical Biology, 14(9), 861–869. https://doi.org/10.1038/s41589-018-0108-2
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2018 | Thesis | IST-REx-ID: 418
Gschaider-Reichhart, E. (2018). Optical and optogenetic control of proliferation and survival . IST Austria. https://doi.org/10.15479/AT:ISTA:th_913
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2018 | Journal Article | IST-REx-ID: 5984   OA
Morri, M., Sanchez-Romero, I., Tichy, A.-M., Kainrath, S., Gerrard, E. J., Hirschfeld, P., … Janovjak, H. L. (2018). Optical functionalization of human class A orphan G-protein-coupled receptors. Nature Communications, 9(1). https://doi.org/10.1038/s41467-018-04342-1
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2018 | Thesis | IST-REx-ID: 6266
Mckenzie, C. (2018). Design and characterization of methods and biological components to realize synthetic neurotransmission . IST Austria. https://doi.org/10.15479/at:ista:th_1055
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2017 | Book Chapter | IST-REx-ID: 958
Mitchell, J., Zhang, W., Herde, M., Henneberger, C., Janovjak, H. L., O’Mara, M., & Jackson, C. (2017). Method for developing optical sensors using a synthetic dye fluorescent protein FRET pair and computational modeling and assessment. In V. Stein (Ed.), Synthetic Protein Switches (Vol. 1596, pp. 89–99). Springer. https://doi.org/10.1007/978-1-4939-6940-1_6
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2017 | Journal Article | IST-REx-ID: 1028   OA
Kainrath, S., Stadler, M., Gschaider-Reichhart, E., Distel, M., & Janovjak, H. L. (2017). Green-light-induced inactivation of receptor signaling using cobalamin-binding domains. Angewandte Chemie - International Edition, 56(16), 4608–4611. https://doi.org/10.1002/anie.201611998
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2017 | Journal Article | IST-REx-ID: 538   OA
Kainrath, S., Stadler, M., Gschaider-Reichhart, E., Distel, M., & Janovjak, H. L. (2017). Grünlicht-induzierte Rezeptorinaktivierung durch Cobalamin-bindende Domänen. Angewandte Chemie, 129(16), 4679–4682. https://doi.org/10.1002/ange.201611998
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2017 | Journal Article | IST-REx-ID: 1026
Agus, V., & Janovjak, H. L. (2017). Optogenetic methods in drug screening: Technologies and applications. Current Opinion in Biotechnology, 48, 8–14. https://doi.org/10.1016/j.copbio.2017.02.006
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2017 | Book Chapter | IST-REx-ID: 957
Clifton, B., Whitfield, J., Sanchez Romero, I., Herde, M., Henneberger, C., Janovjak, H. L., & Jackson, C. (2017). Ancestral protein reconstruction and circular permutation for improving the stability and dynamic range of FRET sensors. In V. Stein (Ed.), Synthetic Protein Switches (Vol. 1596, pp. 71–87). Springer. https://doi.org/10.1007/978-1-4939-6940-1_5
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2016 | Journal Article | IST-REx-ID: 1440
Janovjak, H. L. (2016). Light at the end of the protein: Crystal structure of a C-terminal light-sensing domain. Structure, 24(2), 213–215. https://doi.org/10.1016/j.str.2016.01.002
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2016 | Journal Article | IST-REx-ID: 1441
Gschaider-Reichhart, E., Inglés Prieto, Á., Tichy, A.-M., Mckenzie, C., & Janovjak, H. L. (2016). A phytochrome sensory domain permits receptor activation by red light. Angewandte Chemie - International Edition, 55(21), 6339–6342. https://doi.org/10.1002/anie.201601736
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2016 | Thesis | IST-REx-ID: 1124
Morri, M. (2016). Optical functionalization of human class A orphan G-protein coupled receptors. IST Austria.
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2016 | Journal Article | IST-REx-ID: 1100
Sako, K., Pradhan, S., Barone, V., Inglés Prieto, Á., Mueller, P., Ruprecht, V., … Heisenberg, C.-P. J. (2016). Optogenetic control of nodal signaling reveals a temporal pattern of nodal signaling regulating cell fate specification during gastrulation. Cell Reports, 16(3), 866–877. https://doi.org/10.1016/j.celrep.2016.06.036
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2016 | Journal Article | IST-REx-ID: 1101
Mitchell, J., Whitfield, J., Zhang, W., Henneberger, C., Janovjak, H. L., O’Mara, M., & Jackson, C. (2016). Rangefinder: A semisynthetic FRET sensor design algorithm. ACS SENSORS, 1(11), 1286–1290. https://doi.org/10.1021/acssensors.6b00576
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2015 | Journal Article | IST-REx-ID: 1611   OA
Whitfield, J., Zhang, W., Herde, M., Clifton, B., Radziejewski, J., Janovjak, H. L., … Jackson, C. (2015). Construction of a robust and sensitive arginine biosensor through ancestral protein reconstruction. Protein Science, 24(9), 1412–1422. https://doi.org/10.1002/pro.2721
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2015 | Journal Article | IST-REx-ID: 1678
Inglés Prieto, Á., Gschaider-Reichhart, E., Muellner, M., Nowak, M., Nijman, S., Grusch, M., & Janovjak, H. L. (2015). Light-assisted small-molecule screening against protein kinases. Nature Chemical Biology, 11(12), 952–954. https://doi.org/10.1038/nchembio.1933
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2015 | Book Chapter | IST-REx-ID: 1549   OA
Mckenzie, C., Sanchez Romero, I., & Janovjak, H. L. (2015). Flipping the photoswitch: Ion channels under light control. In Novel chemical tools to study ion channel biology (Vol. 869, pp. 101–117). Springer. https://doi.org/10.1007/978-1-4939-2845-3_6
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2015 | Journal Article | IST-REx-ID: 1867
Hühner, J., Inglés Prieto, Á., Neusüß, C., Lämmerhofer, M., & Janovjak, H. L. (2015). Quantification of riboflavin, flavin mononucleotide, and flavin adenine dinucleotide in mammalian model cells by CE with LED-induced fluorescence detection. Electrophoresis, 36(4), 518–525. https://doi.org/10.1002/elps.201400451
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2014 | Journal Article | IST-REx-ID: 1844   OA
Risso, V., Manssour Triedo, F., Delgado Delgado, A., Arco, R., Barroso Deljesús, A., Inglés Prieto, Á., … Sánchez Ruiz, J. (2014). Mutational studies on resurrected ancestral proteins reveal conservation of site-specific amino acid preferences throughout evolutionary history. Molecular Biology and Evolution, 32(2), 440–455. https://doi.org/10.1093/molbev/msu312
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2014 | Journal Article | IST-REx-ID: 2032   OA
Inglés Prieto, Á., Gschaider-Reichhart, E., Schelch, K., Janovjak, H. L., & Grusch, M. (2014). The optogenetic promise for oncology: Episode I. Molecular and Cellular Oncology, 1(4), e964045. https://doi.org/10.4161/23723548.2014.964045
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2014 | Journal Article | IST-REx-ID: 2084
Grusch, M., Schelch, K., Riedler, R., Gschaider-Reichhart, E., Differ, C., Berger, W., … Janovjak, H. L. (2014). Spatio-temporally precise activation of engineered receptor tyrosine kinases by light. EMBO Journal, 33(15), 1713–1726. https://doi.org/10.15252/embj.201387695
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2013 | Journal Article | IST-REx-ID: 505
Greimel, K., Perz, V., Koren, K., Feola, R., Temel, A., Sohar, C., … Guebitz, G. (2013). Banning toxic heavy-metal catalysts from paints: Enzymatic cross-linking of alkyd resins. Green Chemistry, 15(2), 381–388. https://doi.org/10.1039/c2gc36666e
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2013 | Journal Article | IST-REx-ID: 2471   OA
Sanchez Romero, I., Ariza, A., Wilson, K., Skjøt, M., Vind, J., De Maria, L., … Sánchez Ruiz, J. (2013). Mechanism of protein kinetic stabilization by engineered disulfide crosslinks. PLoS One, 8(7). https://doi.org/10.1371/journal.pone.0070013
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2013 | Journal Article | IST-REx-ID: 2856   OA
Levitz, J., Pantoja, C., Gaub, B., Janovjak, H. L., Reiner, A., Hoagland, A., … Isacoff, E. (2013). Optical control of metabotropic glutamate receptors. Nature Neuroscience, 16, 507–516. https://doi.org/10.1038/nn.3346
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2013 | Journal Article | IST-REx-ID: 2857   OA
Szobota, S., Mckenzie, C., & Janovjak, H. L. (2013). Optical control of ligand-gated ion channels. Methods in Molecular Biology, 998, 417–435. https://doi.org/10.1007/978-1-62703-351-0_32
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2011 | Journal Article | IST-REx-ID: 3405   OA
Janovjak, H. L., Sandoz, G., & Isacoff, E. (2011). Modern ionotropic glutamate receptor with a K+ selectivity signature sequence. Nature Communications, 2(232), 1–6. https://doi.org/10.1038/ncomms1231
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