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53 Publications

2019 | Journal Article | IST-REx-ID: 6025   OA
Light-activated Frizzled7 reveals a permissive role of non-canonical wnt signaling in mesendoderm cell migration
D. Capek, M. Smutny, A.M. Tichy, M. Morri, H.L. Janovjak, C.-P.J. Heisenberg, ELife 8 (2019).
View | Files available | DOI
 
2018 | Journal Article | IST-REx-ID: 137
Monitoring hippocampal glycine with the computationally designed optical sensor GlyFS
W. Zhang, M. Herde, J. Mitchell, J. Whitfield, A. Wulff, V. Vongsouthi, I. Sanchez Romero, P. Gulakova, D. Minge, B. Breithausen, S. Schoch, H.L. Janovjak, C. Jackson, C. Henneberger, Nature Chemical Biology 14 (2018) 861–869.
View | DOI | PubMed | Europe PMC
 
2018 | Thesis | IST-REx-ID: 418   OA
Optical and optogenetic control of proliferation and survival
E. Gschaider-Reichhart, Optical and Optogenetic Control of Proliferation and Survival , IST Austria, 2018.
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2018 | Journal Article | IST-REx-ID: 5984   OA
Optical functionalization of human class A orphan G-protein-coupled receptors
M. Morri, I. Sanchez-Romero, A.-M. Tichy, S. Kainrath, E.J. Gerrard, P. Hirschfeld, J. Schwarz, H.L. Janovjak, Nature Communications 9 (2018).
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2017 | Book Chapter | IST-REx-ID: 958
Method for developing optical sensors using a synthetic dye fluorescent protein FRET pair and computational modeling and assessment
J. Mitchell, W. Zhang, M. Herde, C. Henneberger, H.L. Janovjak, M. O’Mara, C. Jackson, in:, V. Stein (Ed.), Synthetic Protein Switches, Springer, 2017, pp. 89–99.
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2017 | Journal Article | IST-REx-ID: 1028   OA
Green-light-induced inactivation of receptor signaling using cobalamin-binding domains
S. Kainrath, M. Stadler, E. Gschaider-Reichhart, M. Distel, H.L. Janovjak, Angewandte Chemie - International Edition 56 (2017) 4608–4611.
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2017 | Journal Article | IST-REx-ID: 538   OA
Grünlicht-induzierte Rezeptorinaktivierung durch Cobalamin-bindende Domänen
S. Kainrath, M. Stadler, E. Gschaider-Reichhart, M. Distel, H.L. Janovjak, Angewandte Chemie 129 (2017) 4679–4682.
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2017 | Journal Article | IST-REx-ID: 1026
Optogenetic methods in drug screening: Technologies and applications
V. Agus, H.L. Janovjak, Current Opinion in Biotechnology 48 (2017) 8–14.
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2017 | Book Chapter | IST-REx-ID: 957
Ancestral protein reconstruction and circular permutation for improving the stability and dynamic range of FRET sensors
B. Clifton, J. Whitfield, I. Sanchez Romero, M. Herde, C. Henneberger, H.L. Janovjak, C. Jackson, in:, V. Stein (Ed.), Synthetic Protein Switches, Springer, 2017, pp. 71–87.
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2016 | Journal Article | IST-REx-ID: 1440 View | DOI
 
2016 | Thesis | IST-REx-ID: 1124
Optical functionalization of human class A orphan G-protein coupled receptors
M. Morri, Optical Functionalization of Human Class A Orphan G-Protein Coupled Receptors, IST Austria, 2016.
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2016 | Journal Article | IST-REx-ID: 1100   OA
Optogenetic control of nodal signaling reveals a temporal pattern of nodal signaling regulating cell fate specification during gastrulation
K. Sako, S. Pradhan, V. Barone, Á. Inglés Prieto, P. Mueller, V. Ruprecht, D. Capek, S. Galande, H.L. Janovjak, C.-P.J. Heisenberg, Cell Reports 16 (2016) 866–877.
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2016 | Journal Article | IST-REx-ID: 1441   OA
A phytochrome sensory domain permits receptor activation by red light
E. Gschaider-Reichhart, Á. Inglés Prieto, A.-M. Tichy, C. Mckenzie, H.L. Janovjak, Angewandte Chemie - International Edition 55 (2016) 6339–6342.
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2016 | Journal Article | IST-REx-ID: 1101
Rangefinder: A semisynthetic FRET sensor design algorithm
J. Mitchell, J. Whitfield, W. Zhang, C. Henneberger, H.L. Janovjak, M. O’Mara, C. Jackson, ACS SENSORS 1 (2016) 1286–1290.
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2015 | Journal Article | IST-REx-ID: 1678   OA
Light-assisted small-molecule screening against protein kinases
Á. Inglés Prieto, E. Gschaider-Reichhart, M. Muellner, M. Nowak, S. Nijman, M. Grusch, H.L. Janovjak, Nature Chemical Biology 11 (2015) 952–954.
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2015 | Journal Article | IST-REx-ID: 1611   OA
Construction of a robust and sensitive arginine biosensor through ancestral protein reconstruction
J. Whitfield, W. Zhang, M. Herde, B. Clifton, J. Radziejewski, H.L. Janovjak, C. Henneberger, C. Jackson, Protein Science 24 (2015) 1412–1422.
View | DOI | Download (ext.) | PubMed | Europe PMC
 
2015 | Book Chapter | IST-REx-ID: 1549   OA
Flipping the photoswitch: Ion channels under light control
C. Mckenzie, I. Sanchez Romero, H.L. Janovjak, in:, Novel Chemical Tools to Study Ion Channel Biology, Springer, 2015, pp. 101–117.
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2015 | Journal Article | IST-REx-ID: 1867
Quantification of riboflavin, flavin mononucleotide, and flavin adenine dinucleotide in mammalian model cells by CE with LED-induced fluorescence detection
J. Hühner, Á. Inglés Prieto, C. Neusüß, M. Lämmerhofer, H.L. Janovjak, Electrophoresis 36 (2015) 518–525.
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2014 | Journal Article | IST-REx-ID: 1844   OA
Mutational studies on resurrected ancestral proteins reveal conservation of site-specific amino acid preferences throughout evolutionary history
V. Risso, F. Manssour Triedo, A. Delgado Delgado, R. Arco, A. Barroso Deljesús, Á. Inglés Prieto, R. Godoy Ruiz, J. Gavira, E. Gaucher, B. Ibarra Molero, J. Sánchez Ruiz, Molecular Biology and Evolution 32 (2014) 440–455.
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2014 | Book Review | IST-REx-ID: 2032   OA
The optogenetic promise for oncology: Episode I
Á. Inglés Prieto, E. Gschaider-Reichhart, K. Schelch, H.L. Janovjak, M. Grusch, Molecular and Cellular Oncology 1 (2014).
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