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134 Publications

2020 | Preprint | IST-REx-ID: 7675 | OA
Normative models of enhancer function
R. Grah, B. Zoller, G. Tkačik, BioRxiv (2020).
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2020 | Journal Article | IST-REx-ID: 8084 | OA
Critical dynamics and coupling in bursts of cortical rhythms indicate non-homeostatic mechanism for sleep-stage transitions and dual role of VLPO neurons in both sleep and wake
F. Lombardi, M. Gómez-Extremera, P. Bernaola-Galván, R. Vetrivelan, C.B. Saper, T.E. Scammell, P.C. Ivanov, Journal of Neuroscience 40 (2020) 171–190.
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2020 | Research Data | IST-REx-ID: 8097 | OA
Analysis scripts and research data for the paper "Mechanisms of drug interactions between translation-inhibiting antibiotics"
B. Kavcic, Analysis Scripts and Research Data for the Paper “Mechanisms of Drug Interactions between Translation-Inhibiting Antibiotics,” IST Austria, 2020.
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2020 | Journal Article | IST-REx-ID: 8105 | OA View | Files available | DOI
 
2020 | Thesis | IST-REx-ID: 8155 | OA
Gene regulation across scales – how biophysical constraints shape evolution
R. Grah, Gene Regulation across Scales – How Biophysical Constraints Shape Evolution, IST Austria, 2020.
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2020 | Research Data | IST-REx-ID: 7383 | OA
Matlab scripts for the Paper: Gene Amplification as a Form of Population-Level Gene Expression regulation
R. Grah, Matlab Scripts for the Paper: Gene Amplification as a Form of Population-Level Gene Expression Regulation, IST Austria, 2020.
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2020 | Thesis | IST-REx-ID: 8657
Perturbations of protein synthesis: from antibiotics to genetics and physiology
B. Kavcic, Perturbations of Protein Synthesis: From Antibiotics to Genetics and Physiology, IST Austria, 2020.
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2020 | Journal Article | IST-REx-ID: 8250 | OA
Mechanisms of drug interactions between translation-inhibiting antibiotics
B. Kavcic, G. Tkačik, M.T. Bollenbach, Nature Communications 11 (2020).
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2020 | Preprint | IST-REx-ID: 7673 | OA
A minimal biophysical model of combined antibiotic action
B. Kavcic, G. Tkačik, T. Bollenbach, BioRxiv (2020).
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2020 | Journal Article | IST-REx-ID: 7652 | OA
Gene amplification as a form of population-level gene expression regulation
I. Tomanek, R. Grah, M. Lagator, A.M.C. Andersson, J.P. Bollback, G. Tkačik, C.C. Guet, Nature Ecology & Evolution 4 (2020) 612–625.
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2019 | Journal Article | IST-REx-ID: 7422 | OA
eGFRD in all dimensions
T.R. Sokolowski, J. Paijmans, L. Bossen, T. Miedema, M. Wehrens, N.B. Becker, K. Kaizu, K. Takahashi, M. Dogterom, P.R. ten Wolde, The Journal of Chemical Physics 150 (2019) 054108.
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2019 | Preprint | IST-REx-ID: 7552 | OA
Action at a distance in transcriptional regulation
W. Bialek, T. Gregor, G. Tkačik, ArXiv:1912.08579 (n.d.).
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2019 | Conference Paper | IST-REx-ID: 7606 | OA
A tight upper bound on mutual information
M. Hledik, T.R. Sokolowski, G. Tkačik, in:, IEEE Information Theory Workshop, ITW 2019, IEEE, 2019, p. 8989292.
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2019 | Journal Article | IST-REx-ID: 6046 | OA
Temporal order and precision of complex stress responses in individual bacteria
K. Mitosch, G. Rieckh, M.T. Bollenbach, Molecular Systems Biology 15 (2019).
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2019 | Journal Article | IST-REx-ID: 6049 | OA
Feedback-induced self-oscillations in large interacting systems subjected to phase transitions
D. De Martino, Journal of Physics A: Mathematical and Theoretical 52 (2019).
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2019 | Thesis | IST-REx-ID: 6071 | OA
Coevolution of transcription factors and their binding sites in sequence space
R. Prizak, Coevolution of Transcription Factors and Their Binding Sites in Sequence Space, IST Austria, 2019.
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2019 | Journal Article | IST-REx-ID: 6090 | OA
Receptor crosstalk improves concentration sensing of multiple ligands
M. Carballo-Pacheco, J. Desponds, T. Gavrilchenko, A. Mayer, R. Prizak, G. Reddy, I. Nemenman, T. Mora, Physical Review E 99 (2019).
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2019 | Thesis | IST-REx-ID: 6473 | OA
Estimating information flow in single cells
S.A. Cepeda Humerez, Estimating Information Flow in Single Cells, IST Austria, 2019.
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2019 | Journal Article | IST-REx-ID: 6784 | OA
Molecular noise of innate immunity shapes bacteria-phage ecologies
J. Ruess, M. Pleska, C.C. Guet, G. Tkačik, PLoS Computational Biology 15 (2019).
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2019 | Journal Article | IST-REx-ID: 6900 | OA
Estimating information in time-varying signals
S.A. Cepeda Humerez, J. Ruess, G. Tkačik, PLoS Computational Biology 15 (2019) e1007290.
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2019 | Preprint | IST-REx-ID: 7083 | OA
Mechanistic origin of drug interactions between translation-inhibiting antibiotics
B. Kavcic, G. Tkačik, T. Bollenbach, BioRxiv (n.d.).
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2019 | Journal Article | IST-REx-ID: 7103 | OA
Non-equilibrium critical dynamics of bursts in θ and δ rhythms as fundamental characteristic of sleep and wake micro-architecture
J.W.J.L. Wang, F. Lombardi, X. Zhang, C. Anaclet, P.C. Ivanov, PLOS Computational Biology 15 (2019).
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2019 | Journal Article | IST-REx-ID: 196 | OA
Harmonic dynamics of the Abelian sandpile
M. Lang, M. Shkolnikov, Proceedings of the National Academy of Sciences 116 (2019) 2821–2830.
View | Files available | DOI | Download Published Version (ext.) | PubMed | Europe PMC | arXiv
 
2019 | Journal Article | IST-REx-ID: 5945 | OA
Optimal decoding of cellular identities in a genetic network
M.D. Petkova, G. Tkačik, W. Bialek, E.F. Wieschaus, T. Gregor, Cell 176 (2019) 844–855.e15.
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2019 | Journal Article | IST-REx-ID: 5817 | OA
Limiting shapes of confined lipid vesicles
B. Kavcic, A. Sakashita, H. Noguchi, P. Ziherl, Soft Matter 15 (2019) 602–614.
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2018 | Journal Article | IST-REx-ID: 406 | OA
Probabilistic models of individual and collective animal behavior
K. Bod’Ová, G. Mitchell, R. Harpaz, E. Schneidman, G. Tkačik, PLoS One 13 (2018).
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2018 | Journal Article | IST-REx-ID: 457
Phage-host population dynamics promotes prophage acquisition in bacteria with innate immunity
M. Pleska, M. Lang, D. Refardt, B. Levin, C.C. Guet, Nature Ecology and Evolution 2 (2018) 359–366.
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2018 | Journal Article | IST-REx-ID: 543 | OA
Toward a unified theory of efficient, predictive, and sparse coding
M.J. Chalk, O. Marre, G. Tkacik, PNAS 115 (2018) 186–191.
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2018 | Research Data | IST-REx-ID: 5584 | OA
Nonlinear decoding of a complex movie from the mammalian retina
S. Deny, O. Marre, V. Botella-Soler, G.S. Martius, G. Tkačik, Nonlinear Decoding of a Complex Movie from the Mammalian Retina, IST Austria, 2018.
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2018 | Research Data | IST-REx-ID: 5585 | OA
Data for the paper Evolutionary potential of transcription factors for gene regulatory rewiring
C. Igler, M. Lagator, G. Tkačik, J.P. Bollback, C.C. Guet, Data for the Paper Evolutionary Potential of Transcription Factors for Gene Regulatory Rewiring, IST Austria, 2018.
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2018 | Research Data | IST-REx-ID: 5587 | OA
Supporting materials "STATISTICAL MECHANICS FOR METABOLIC NETWORKS IN STEADY-STATE GROWTH"
D. De Martino, G. Tkačik, Supporting Materials “STATISTICAL MECHANICS FOR METABOLIC NETWORKS IN STEADY-STATE GROWTH,” IST Austria, 2018.
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2018 | Journal Article | IST-REx-ID: 607 | OA
Well posedness and maximum entropy approximation for the dynamics of quantitative traits
K. Bodova, J. Haskovec, P. Markowich, Physica D: Nonlinear Phenomena 376–377 (2018) 108–120.
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2018 | Journal Article | IST-REx-ID: 281 | OA
Distributed and dynamic intracellular organization of extracellular information
A. Granados, J. Pietsch, S.A. Cepeda Humerez, I. Farquhar, G. Tkacik, P. Swain, PNAS 115 (2018) 6088–6093.
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2018 | Journal Article | IST-REx-ID: 292 | OA
Nonlinear decoding of a complex movie from the mammalian retina
V. Botella Soler, S. Deny, G.S. Martius, O. Marre, G. Tkačik, PLoS Computational Biology 14 (2018).
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2018 | Journal Article | IST-REx-ID: 305
Fabrication and operation of microfluidic hanging drop networks
P. Misun, A. Birchler, M. Lang, A. Hierlemann, O. Frey, Methods in Molecular Biology 1771 (2018) 183–202.
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2018 | Journal Article | IST-REx-ID: 306 | OA View | Files available | DOI
 
2018 | Journal Article | IST-REx-ID: 31 | OA
Separating intrinsic interactions from extrinsic correlations in a network of sensory neurons
U. Ferrari, S. Deny, M.J. Chalk, G. Tkacik, O. Marre, T. Mora, Physical Review E 98 (2018) 042410.
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2018 | Journal Article | IST-REx-ID: 67 | OA
Evolutionary potential of transcription factors for gene regulatory rewiring
C. Igler, M. Lagator, G. Tkačik, J.P. Bollback, C.C. Guet, Nature Ecology and Evolution 2 (2018) 1633–1643.
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2018 | Journal Article | IST-REx-ID: 161 | OA
Statistical mechanics for metabolic networks during steady state growth
D. De Martino, A.A. Mc, T. Bergmiller, C.C. Guet, G. Tkačik, Nature Communications 9 (2018).
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2018 | Journal Article | IST-REx-ID: 19 | OA
Nonoptimal gene expression creates latent potential for antibiotic resistance
A. Palmer, R.P. Chait, R. Kishony, Molecular Biology and Evolution 35 (2018) 2669–2684.
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2018 | Journal Article | IST-REx-ID: 316 | OA
Evolutionary pathways for the generation of new self-incompatibility haplotypes in a non-self recognition system
K. Bod’ová, T. Priklopil, D. Field, N.H. Barton, M. Pickup, Genetics 209 (2018) 861–883.
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2017 | Journal Article | IST-REx-ID: 2016 | OA
Exact goodness-of-fit testing for the Ising model
A. Martin Del Campo Sanchez, S.A. Cepeda Humerez, C. Uhler, Scandinavian Journal of Statistics 44 (2017) 285–306.
View | Files available | DOI | Download Preprint (ext.) | arXiv
 
2017 | Journal Article | IST-REx-ID: 720 | OA View | Files available | DOI
 
2017 | Journal Article | IST-REx-ID: 725 | OA
Discrete modes of social information processing predict individual behavior of fish in a group
R. Harpaz, G. Tkacik, E. Schneidman, PNAS 114 (2017) 10149–10154.
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2017 | Journal Article | IST-REx-ID: 730
Maximum entropy models as a tool for building precise neural controls
C. Savin, G. Tkacik, Current Opinion in Neurobiology 46 (2017) 120–126.
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2017 | Journal Article | IST-REx-ID: 735
An effective feedback loop between cell-cell contact duration and morphogen signaling determines cell fate
V. Barone, M. Lang, G. Krens, S. Pradhan, S. Shamipour, K. Sako, M.K. Sikora, C.C. Guet, C.-P.J. Heisenberg, Developmental Cell 43 (2017) 198–211.
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2017 | Research Data | IST-REx-ID: 5560 | OA
Biased partitioning of the multi-drug efflux pump AcrAB-TolC underlies long-lived phenotypic heterogeneity
T. Bergmiller, A.M. Andersson, K. Tomasek, E. Balleza, D. Kiviet, R. Hauschild, G. Tkačik, C.C. Guet, Biased Partitioning of the Multi-Drug Efflux Pump AcrAB-TolC Underlies Long-Lived Phenotypic Heterogeneity, IST Austria, 2017.
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2017 | Research Data | IST-REx-ID: 5562 | OA
Multi-electrode array recording from salamander retinal ganglion cells
O. Marre, G. Tkačik, D. Amodei, E. Schneidman, W. Bialek, M. Berry, Multi-Electrode Array Recording from Salamander Retinal Ganglion Cells, IST Austria, 2017.
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2017 | Journal Article | IST-REx-ID: 613 | OA
Shaping bacterial population behavior through computer interfaced control of individual cells
R.P. Chait, J. Ruess, T. Bergmiller, G. Tkačik, C.C. Guet, Nature Communications 8 (2017).
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