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142 Publications
2020 | Preprint | IST-REx-ID: 7553 | 
Statistical analysis and optimality of biological systems
W.F. Mlynarski, M. Hledik, T.R. Sokolowski, G. Tkačik, BioRxiv (n.d.).
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W.F. Mlynarski, M. Hledik, T.R. Sokolowski, G. Tkačik, BioRxiv (n.d.).
2020 | Journal Article | IST-REx-ID: 7569 |
The relation between crosstalk and gene regulation form revisited
R. Grah, T. Friedlander, PLOS Computational Biology 16 (2020).
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R. Grah, T. Friedlander, PLOS Computational Biology 16 (2020).
2020 | Journal Article | IST-REx-ID: 7652 |
Gene amplification as a form of population-level gene expression regulation
I. Tomanek, R. Grah, M. Lagator, A.M.C. Andersson, J.P. Bollback, G. Tkačik, C.C. Guet, Nature Ecology & Evolution 4 (2020) 612–625.
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I. Tomanek, R. Grah, M. Lagator, A.M.C. Andersson, J.P. Bollback, G. Tkačik, C.C. Guet, Nature Ecology & Evolution 4 (2020) 612–625.
2020 | Journal Article | IST-REx-ID: 7656 |
Clustering of neural activity: A design principle for population codes
M.J. Berry, G. Tkačik, Frontiers in Computational Neuroscience 14 (2020).
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| PubMed | Europe PMC
M.J. Berry, G. Tkačik, Frontiers in Computational Neuroscience 14 (2020).
2020 | Preprint | IST-REx-ID: 7673 |
A minimal biophysical model of combined antibiotic action
B. Kavcic, G. Tkačik, M.T. Bollenbach, BioRxiv (2020).
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B. Kavcic, G. Tkačik, M.T. Bollenbach, BioRxiv (2020).
2020 | Preprint | IST-REx-ID: 7675 |
Normative models of enhancer function
R. Grah, B. Zoller, G. Tkačik, BioRxiv (2020).
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R. Grah, B. Zoller, G. Tkačik, BioRxiv (2020).
2020 | Research Data | IST-REx-ID: 8930 |
Analysis scripts and research data for the paper "Minimal biophysical model of combined antibiotic action"
B. Kavcic, (2020).
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B. Kavcic, (2020).
2020 | Journal Article | IST-REx-ID: 8955 |
Network physiology of cortico–muscular interactions
R. Rizzo, X. Zhang, J.W.J.L. Wang, F. Lombardi, P.C. Ivanov, Frontiers in Physiology 11 (2020).
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R. Rizzo, X. Zhang, J.W.J.L. Wang, F. Lombardi, P.C. Ivanov, Frontiers in Physiology 11 (2020).
2020 | Journal Article | IST-REx-ID: 9000 |
Nonequilibrium models of optimal enhancer function
R. Grah, B. Zoller, G. Tkačik, PNAS 117 (2020) 31614–31622.
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R. Grah, B. Zoller, G. Tkačik, PNAS 117 (2020) 31614–31622.
2019 | Journal Article | IST-REx-ID: 196 |
Harmonic dynamics of the Abelian sandpile
M. Lang, M. Shkolnikov, Proceedings of the National Academy of Sciences 116 (2019) 2821–2830.
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| arXiv
M. Lang, M. Shkolnikov, Proceedings of the National Academy of Sciences 116 (2019) 2821–2830.
2019 | Journal Article | IST-REx-ID: 7422 |
eGFRD in all dimensions
T.R. Sokolowski, J. Paijmans, L. Bossen, T. Miedema, M. Wehrens, N.B. Becker, K. Kaizu, K. Takahashi, M. Dogterom, P.R. ten Wolde, The Journal of Chemical Physics 150 (2019).
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T.R. Sokolowski, J. Paijmans, L. Bossen, T. Miedema, M. Wehrens, N.B. Becker, K. Kaizu, K. Takahashi, M. Dogterom, P.R. ten Wolde, The Journal of Chemical Physics 150 (2019).
2019 | Preprint | IST-REx-ID: 7552 |
Action at a distance in transcriptional regulation
W. Bialek, T. Gregor, G. Tkačik, ArXiv:1912.08579 (n.d.).
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W. Bialek, T. Gregor, G. Tkačik, ArXiv:1912.08579 (n.d.).
2019 | Conference Paper | IST-REx-ID: 7606 |
A tight upper bound on mutual information
M. Hledik, T.R. Sokolowski, G. Tkačik, in:, IEEE Information Theory Workshop, ITW 2019, IEEE, 2019.
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M. Hledik, T.R. Sokolowski, G. Tkačik, in:, IEEE Information Theory Workshop, ITW 2019, IEEE, 2019.
2019 | Journal Article | IST-REx-ID: 5817 |
Limiting shapes of confined lipid vesicles
B. Kavcic, A. Sakashita, H. Noguchi, P. Ziherl, Soft Matter 15 (2019) 602–614.
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B. Kavcic, A. Sakashita, H. Noguchi, P. Ziherl, Soft Matter 15 (2019) 602–614.
2019 | Journal Article | IST-REx-ID: 5945 |
Optimal decoding of cellular identities in a genetic network
M.D. Petkova, G. Tkačik, W. Bialek, E.F. Wieschaus, T. Gregor, Cell 176 (2019) 844–855.e15.
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M.D. Petkova, G. Tkačik, W. Bialek, E.F. Wieschaus, T. Gregor, Cell 176 (2019) 844–855.e15.
2019 | Journal Article | IST-REx-ID: 6046 |
Temporal order and precision of complex stress responses in individual bacteria
K. Mitosch, G. Rieckh, M.T. Bollenbach, Molecular Systems Biology 15 (2019).
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K. Mitosch, G. Rieckh, M.T. Bollenbach, Molecular Systems Biology 15 (2019).
2019 | Journal Article | IST-REx-ID: 6049 |
Feedback-induced self-oscillations in large interacting systems subjected to phase transitions
D. De Martino, Journal of Physics A: Mathematical and Theoretical 52 (2019).
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D. De Martino, Journal of Physics A: Mathematical and Theoretical 52 (2019).
2019 | Thesis | IST-REx-ID: 6071 |
Coevolution of transcription factors and their binding sites in sequence space
R. Prizak, Coevolution of Transcription Factors and Their Binding Sites in Sequence Space, IST Austria, 2019.
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R. Prizak, Coevolution of Transcription Factors and Their Binding Sites in Sequence Space, IST Austria, 2019.
2019 | Journal Article | IST-REx-ID: 6090 |
Receptor crosstalk improves concentration sensing of multiple ligands
M. Carballo-Pacheco, J. Desponds, T. Gavrilchenko, A. Mayer, R. Prizak, G. Reddy, I. Nemenman, T. Mora, Physical Review E 99 (2019).
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M. Carballo-Pacheco, J. Desponds, T. Gavrilchenko, A. Mayer, R. Prizak, G. Reddy, I. Nemenman, T. Mora, Physical Review E 99 (2019).
2019 | Thesis | IST-REx-ID: 6473 |
Estimating information flow in single cells
S.A. Cepeda Humerez, Estimating Information Flow in Single Cells, IST Austria, 2019.
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S.A. Cepeda Humerez, Estimating Information Flow in Single Cells, IST Austria, 2019.
2019 | Journal Article | IST-REx-ID: 6784 |
Molecular noise of innate immunity shapes bacteria-phage ecologies
J. Ruess, M. Pleska, C.C. Guet, G. Tkačik, PLoS Computational Biology 15 (2019).
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J. Ruess, M. Pleska, C.C. Guet, G. Tkačik, PLoS Computational Biology 15 (2019).
2019 | Journal Article | IST-REx-ID: 6900 |
Estimating information in time-varying signals
S.A. Cepeda Humerez, J. Ruess, G. Tkačik, PLoS Computational Biology 15 (2019) e1007290.
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S.A. Cepeda Humerez, J. Ruess, G. Tkačik, PLoS Computational Biology 15 (2019) e1007290.
2019 | Journal Article | IST-REx-ID: 7103 |
Non-equilibrium critical dynamics of bursts in θ and δ rhythms as fundamental characteristic of sleep and wake micro-architecture
J.W.J.L. Wang, F. Lombardi, X. Zhang, C. Anaclet, P.C. Ivanov, PLOS Computational Biology 15 (2019).
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J.W.J.L. Wang, F. Lombardi, X. Zhang, C. Anaclet, P.C. Ivanov, PLOS Computational Biology 15 (2019).
2018 | Journal Article | IST-REx-ID: 281 |
Distributed and dynamic intracellular organization of extracellular information
A. Granados, J. Pietsch, S.A. Cepeda Humerez, I. Farquhar, G. Tkačik, P. Swain, PNAS 115 (2018) 6088–6093.
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A. Granados, J. Pietsch, S.A. Cepeda Humerez, I. Farquhar, G. Tkačik, P. Swain, PNAS 115 (2018) 6088–6093.
2018 | Journal Article | IST-REx-ID: 292 |
Nonlinear decoding of a complex movie from the mammalian retina
V. Botella Soler, S. Deny, G.S. Martius, O. Marre, G. Tkačik, PLoS Computational Biology 14 (2018).
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V. Botella Soler, S. Deny, G.S. Martius, O. Marre, G. Tkačik, PLoS Computational Biology 14 (2018).
2018 | Journal Article | IST-REx-ID: 19 |
Nonoptimal gene expression creates latent potential for antibiotic resistance
A. Palmer, R.P. Chait, R. Kishony, Molecular Biology and Evolution 35 (2018) 2669–2684.
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A. Palmer, R.P. Chait, R. Kishony, Molecular Biology and Evolution 35 (2018) 2669–2684.
2018 | Journal Article | IST-REx-ID: 543 |
Toward a unified theory of efficient, predictive, and sparse coding
M.J. Chalk, O. Marre, G. Tkačik, PNAS 115 (2018) 186–191.
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M.J. Chalk, O. Marre, G. Tkačik, PNAS 115 (2018) 186–191.
2018 | Research Data | IST-REx-ID: 5584 |
Nonlinear decoding of a complex movie from the mammalian retina
S. Deny, O. Marre, V. Botella-Soler, G.S. Martius, G. Tkačik, (2018).
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S. Deny, O. Marre, V. Botella-Soler, G.S. Martius, G. Tkačik, (2018).
2018 | Research Data | IST-REx-ID: 5587 |
Supporting materials "STATISTICAL MECHANICS FOR METABOLIC NETWORKS IN STEADY-STATE GROWTH"
D. De Martino, G. Tkačik, (2018).
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D. De Martino, G. Tkačik, (2018).
2018 | Journal Article | IST-REx-ID: 607 |
Well posedness and maximum entropy approximation for the dynamics of quantitative traits
K. Bod’ová, J. Haskovec, P. Markowich, Physica D: Nonlinear Phenomena 376–377 (2018) 108–120.
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| arXiv
K. Bod’ová, J. Haskovec, P. Markowich, Physica D: Nonlinear Phenomena 376–377 (2018) 108–120.
2018 | Journal Article | IST-REx-ID: 161 |
Statistical mechanics for metabolic networks during steady state growth
D. De Martino, A.A. Mc, T. Bergmiller, C.C. Guet, G. Tkačik, Nature Communications 9 (2018).
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D. De Martino, A.A. Mc, T. Bergmiller, C.C. Guet, G. Tkačik, Nature Communications 9 (2018).
2018 | Journal Article | IST-REx-ID: 406 |
Probabilistic models of individual and collective animal behavior
K. Bod’Ová, G. Mitchell, R. Harpaz, E. Schneidman, G. Tkačik, PLoS One 13 (2018).
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K. Bod’Ová, G. Mitchell, R. Harpaz, E. Schneidman, G. Tkačik, PLoS One 13 (2018).
2018 | Journal Article | IST-REx-ID: 457
Phage-host population dynamics promotes prophage acquisition in bacteria with innate immunity
M. Pleska, M. Lang, D. Refardt, B. Levin, C.C. Guet, Nature Ecology and Evolution 2 (2018) 359–366.
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M. Pleska, M. Lang, D. Refardt, B. Levin, C.C. Guet, Nature Ecology and Evolution 2 (2018) 359–366.
2018 | Journal Article | IST-REx-ID: 305
Fabrication and operation of microfluidic hanging drop networks
P. Misun, A. Birchler, M. Lang, A. Hierlemann, O. Frey, Methods in Molecular Biology 1771 (2018) 183–202.
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P. Misun, A. Birchler, M. Lang, A. Hierlemann, O. Frey, Methods in Molecular Biology 1771 (2018) 183–202.
2018 | Journal Article | IST-REx-ID: 306 |
An introduction to the maximum entropy approach and its application to inference problems in biology
A. De Martino, D. De Martino, Heliyon 4 (2018).
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A. De Martino, D. De Martino, Heliyon 4 (2018).
2018 | Journal Article | IST-REx-ID: 31 |
Separating intrinsic interactions from extrinsic correlations in a network of sensory neurons
U. Ferrari, S. Deny, M.J. Chalk, G. Tkačik, O. Marre, T. Mora, Physical Review E 98 (2018).
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U. Ferrari, S. Deny, M.J. Chalk, G. Tkačik, O. Marre, T. Mora, Physical Review E 98 (2018).
2018 | Journal Article | IST-REx-ID: 316 |
Evolutionary pathways for the generation of new self-incompatibility haplotypes in a non-self recognition system
K. Bod’ová, T. Priklopil, D. Field, N.H. Barton, M. Pickup, Genetics 209 (2018) 861–883.
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K. Bod’ová, T. Priklopil, D. Field, N.H. Barton, M. Pickup, Genetics 209 (2018) 861–883.
2018 | Journal Article | IST-REx-ID: 67 |
Evolutionary potential of transcription factors for gene regulatory rewiring
C. Igler, M. Lagator, G. Tkačik, J.P. Bollback, C.C. Guet, Nature Ecology and Evolution 2 (2018) 1633–1643.
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C. Igler, M. Lagator, G. Tkačik, J.P. Bollback, C.C. Guet, Nature Ecology and Evolution 2 (2018) 1633–1643.
2018 | Research Data | IST-REx-ID: 5585 |
Data for the paper Evolutionary potential of transcription factors for gene regulatory rewiring
C. Igler, M. Lagator, G. Tkačik, J.P. Bollback, C.C. Guet, (2018).
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C. Igler, M. Lagator, G. Tkačik, J.P. Bollback, C.C. Guet, (2018).
2017 | Journal Article | IST-REx-ID: 823 |
Phase transitions in integer linear problems
S. Colabrese, D. De Martino, L. Leuzzi, E. Marinari, Journal of Statistical Mechanics: Theory and Experiment 2017 (2017).
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S. Colabrese, D. De Martino, L. Leuzzi, E. Marinari, Journal of Statistical Mechanics: Theory and Experiment 2017 (2017).
2017 | Journal Article | IST-REx-ID: 2016 |
Exact goodness-of-fit testing for the Ising model
A. Martin Del Campo Sanchez, S.A. Cepeda Humerez, C. Uhler, Scandinavian Journal of Statistics 44 (2017) 285–306.
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| arXiv
A. Martin Del Campo Sanchez, S.A. Cepeda Humerez, C. Uhler, Scandinavian Journal of Statistics 44 (2017) 285–306.
2017 | Journal Article | IST-REx-ID: 720 |
Probabilistic models for neural populations that naturally capture global coupling and criticality
J. Humplik, G. Tkačik, PLoS Computational Biology 13 (2017).
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J. Humplik, G. Tkačik, PLoS Computational Biology 13 (2017).
2017 | Journal Article | IST-REx-ID: 725 |
Discrete modes of social information processing predict individual behavior of fish in a group
R. Harpaz, G. Tkačik, E. Schneidman, PNAS 114 (2017) 10149–10154.
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R. Harpaz, G. Tkačik, E. Schneidman, PNAS 114 (2017) 10149–10154.
2017 | Journal Article | IST-REx-ID: 730
Maximum entropy models as a tool for building precise neural controls
C. Savin, G. Tkačik, Current Opinion in Neurobiology 46 (2017) 120–126.
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C. Savin, G. Tkačik, Current Opinion in Neurobiology 46 (2017) 120–126.
2017 | Journal Article | IST-REx-ID: 735
An effective feedback loop between cell-cell contact duration and morphogen signaling determines cell fate
V. Barone, M. Lang, G. Krens, S. Pradhan, S. Shamipour, K. Sako, M.K. Sikora, C.C. Guet, C.-P.J. Heisenberg, Developmental Cell 43 (2017) 198–211.
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V. Barone, M. Lang, G. Krens, S. Pradhan, S. Shamipour, K. Sako, M.K. Sikora, C.C. Guet, C.-P.J. Heisenberg, Developmental Cell 43 (2017) 198–211.
2017 | Journal Article | IST-REx-ID: 548 |
Maximum entropy modeling of metabolic networks by constraining growth-rate moments predicts coexistence of phenotypes
D. De Martino, Physical Review E 96 (2017).
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D. De Martino, Physical Review E 96 (2017).
2017 | Research Data | IST-REx-ID: 5560 |
Biased partitioning of the multi-drug efflux pump AcrAB-TolC underlies long-lived phenotypic heterogeneity
T. Bergmiller, A.M. Andersson, K. Tomasek, E. Balleza, D. Kiviet, R. Hauschild, G. Tkačik, C.C. Guet, (2017).
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T. Bergmiller, A.M. Andersson, K. Tomasek, E. Balleza, D. Kiviet, R. Hauschild, G. Tkačik, C.C. Guet, (2017).
2017 | Research Data | IST-REx-ID: 5562 |
Multi-electrode array recording from salamander retinal ganglion cells
O. Marre, G. Tkačik, D. Amodei, E. Schneidman, W. Bialek, M. Berry, (2017).
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O. Marre, G. Tkačik, D. Amodei, E. Schneidman, W. Bialek, M. Berry, (2017).
2017 | Journal Article | IST-REx-ID: 613 |
Shaping bacterial population behavior through computer interfaced control of individual cells
R.P. Chait, J. Ruess, T. Bergmiller, G. Tkačik, C.C. Guet, Nature Communications 8 (2017).
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R.P. Chait, J. Ruess, T. Bergmiller, G. Tkačik, C.C. Guet, Nature Communications 8 (2017).
2017 | Conference Paper | IST-REx-ID: 652
Dynamical self consistency leads to behavioral development and emergent social interactions in robots
R. Der, G.S. Martius, in:, IEEE, 2017.
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R. Der, G.S. Martius, in:, IEEE, 2017.