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130 Publications
2016 | Journal Article | IST-REx-ID: 1290 |

Compounds that select against the tetracycline-resistance efflux pump
L. Stone, M. Baym, T. Lieberman, R.P. Chait, J. Clardy, R. Kishony, Nature Chemical Biology 12 (2016) 902–904.
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L. Stone, M. Baym, T. Lieberman, R.P. Chait, J. Clardy, R. Kishony, Nature Chemical Biology 12 (2016) 902–904.
2016 | Conference Paper | IST-REx-ID: 1320
Scale-invariant systems realize nonlinear differential operators
M. Lang, E. Sontag, in:, IEEE, 2016.
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M. Lang, E. Sontag, in:, IEEE, 2016.
2016 | Journal Article | IST-REx-ID: 1332 |

Pervasive selection for and against antibiotic resistance in inhomogeneous multistress environments
R.P. Chait, A. Palmer, I. Yelin, R. Kishony, Nature Communications 7 (2016).
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R.P. Chait, A. Palmer, I. Yelin, R. Kishony, Nature Communications 7 (2016).
2016 | Journal Article | IST-REx-ID: 1342 |

Spatiotemporal microbial evolution on antibiotic landscapes
M. Baym, T. Lieberman, E. Kelsic, R.P. Chait, R. Gross, I. Yelin, R. Kishony, Science 353 (2016) 1147–1151.
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M. Baym, T. Lieberman, E. Kelsic, R.P. Chait, R. Gross, I. Yelin, R. Kishony, Science 353 (2016) 1147–1151.
2016 | Journal Article | IST-REx-ID: 1394 |

Growth against entropy in bacterial metabolism: the phenotypic trade-off behind empirical growth rate distributions in E. coli
D. De Martino, F. Capuani, A. De Martino, Physical Biology 13 (2016).
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D. De Martino, F. Capuani, A. De Martino, Physical Biology 13 (2016).
2016 | Journal Article | IST-REx-ID: 1420 |

A general approximation for the dynamics of quantitative traits
K. Bod’ová, G. Tkačik, N.H. Barton, Genetics 202 (2016) 1523–1548.
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| arXiv
K. Bod’ová, G. Tkačik, N.H. Barton, Genetics 202 (2016) 1523–1548.
2016 | Journal Article | IST-REx-ID: 1485 |

Genome-scale estimate of the metabolic turnover of E. Coli from the energy balance analysis
D. De Martino, Physical Biology 13 (2016).
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D. De Martino, Physical Biology 13 (2016).
2016 | Journal Article | IST-REx-ID: 1148
Adaptive moment closure for parameter inference of biochemical reaction networks
C. Schilling, S. Bogomolov, T.A. Henzinger, A. Podelski, J. Ruess, Biosystems 149 (2016) 15–25.
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C. Schilling, S. Bogomolov, T.A. Henzinger, A. Podelski, J. Ruess, Biosystems 149 (2016) 15–25.
2016 | Journal Article | IST-REx-ID: 1358 |

Intrinsic limits to gene regulation by global crosstalk
T. Friedlander, R. Prizak, C.C. Guet, N.H. Barton, G. Tkačik, Nature Communications 7 (2016).
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T. Friedlander, R. Prizak, C.C. Guet, N.H. Barton, G. Tkačik, Nature Communications 7 (2016).
2016 | Conference Paper | IST-REx-ID: 8094 |

Self-organized control of an tendon driven arm by differential extrinsic plasticity
G.S. Martius, R. Hostettler, A. Knoll, R. Der, in:, Proceedings of the Artificial Life Conference 2016, MIT Press, 2016, pp. 142–143.
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G.S. Martius, R. Hostettler, A. Knoll, R. Der, in:, Proceedings of the Artificial Life Conference 2016, MIT Press, 2016, pp. 142–143.
2016 | Conference Paper | IST-REx-ID: 948
Neurons equipped with intrinsic plasticity learn stimulus intensity statistics
T. Monk, C. Savin, J. Lücke, in:, Neural Information Processing Systems, 2016, pp. 4285–4293.
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T. Monk, C. Savin, J. Lücke, in:, Neural Information Processing Systems, 2016, pp. 4285–4293.
2015 | Journal Article | IST-REx-ID: 1564 |

Editorial: Emergent neural computation from the interaction of different forms of plasticity
M. Gilson, C. Savin, F. Zenke, Frontiers in Computational Neuroscience 9 (2015).
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M. Gilson, C. Savin, F. Zenke, Frontiers in Computational Neuroscience 9 (2015).
2015 | Journal Article | IST-REx-ID: 1538 |

Iterative experiment design guides the characterization of a light-inducible gene expression circuit
J. Ruess, F. Parise, A. Milias Argeitis, M. Khammash, J. Lygeros, PNAS 112 (2015) 8148–8153.
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J. Ruess, F. Parise, A. Milias Argeitis, M. Khammash, J. Lygeros, PNAS 112 (2015) 8148–8153.
2015 | Journal Article | IST-REx-ID: 1539 |

Minimal moment equations for stochastic models of biochemical reaction networks with partially finite state space
J. Ruess, Journal of Chemical Physics 143 (2015).
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J. Ruess, Journal of Chemical Physics 143 (2015).
2015 | Journal Article | IST-REx-ID: 1570 |

Novel plasticity rule can explain the development of sensorimotor intelligence
R. Der, G.S. Martius, PNAS 112 (2015) E6224–E6232.
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R. Der, G.S. Martius, PNAS 112 (2015) E6224–E6232.
2015 | Journal Article | IST-REx-ID: 1655 |

Quantifying emergent behavior of autonomous robots
G.S. Martius, E. Olbrich, Entropy 17 (2015) 7266–7297.
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G.S. Martius, E. Olbrich, Entropy 17 (2015) 7266–7297.
2015 | Conference Paper | IST-REx-ID: 1658
Adaptive moment closure for parameter inference of biochemical reaction networks
S. Bogomolov, T.A. Henzinger, A. Podelski, J. Ruess, C. Schilling, 9308 (2015) 77–89.
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S. Bogomolov, T.A. Henzinger, A. Podelski, J. Ruess, C. Schilling, 9308 (2015) 77–89.
2015 | Journal Article | IST-REx-ID: 1666 |

Dynamics of transcription factor binding site evolution
M. Tugrul, T. Paixao, N.H. Barton, G. Tkačik, PLoS Genetics 11 (2015).
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M. Tugrul, T. Paixao, N.H. Barton, G. Tkačik, PLoS Genetics 11 (2015).
2015 | Journal Article | IST-REx-ID: 1697 |

High accuracy decoding of dynamical motion from a large retinal population
O. Marre, V. Botella Soler, K. Simmons, T. Mora, G. Tkačik, M. Berry, PLoS Computational Biology 11 (2015).
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O. Marre, V. Botella Soler, K. Simmons, T. Mora, G. Tkačik, M. Berry, PLoS Computational Biology 11 (2015).
2015 | Journal Article | IST-REx-ID: 1701 |

Thermodynamics and signatures of criticality in a network of neurons
G. Tkačik, T. Mora, O. Marre, D. Amodei, S. Palmer, M. Berry Ii, W. Bialek, PNAS 112 (2015) 11508–11513.
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G. Tkačik, T. Mora, O. Marre, D. Amodei, S. Palmer, M. Berry Ii, W. Bialek, PNAS 112 (2015) 11508–11513.
2015 | Journal Article | IST-REx-ID: 1827 |

Evolution of bow-tie architectures in biology
T. Friedlander, A. Mayo, T. Tlusty, U. Alon, PLoS Computational Biology 11 (2015).
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T. Friedlander, A. Mayo, T. Tlusty, U. Alon, PLoS Computational Biology 11 (2015).
2015 | Journal Article | IST-REx-ID: 1861
Moment-based methods for parameter inference and experiment design for stochastic biochemical reaction networks
J. Ruess, J. Lygeros, ACM Transactions on Modeling and Computer Simulation 25 (2015).
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J. Ruess, J. Lygeros, ACM Transactions on Modeling and Computer Simulation 25 (2015).
2015 | Journal Article | IST-REx-ID: 1885 |

Positional information, positional error, and readout precision in morphogenesis: A mathematical framework
G. Tkačik, J. Dubuis, M. Petkova, T. Gregor, Genetics 199 (2015) 39–59.
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G. Tkačik, J. Dubuis, M. Petkova, T. Gregor, Genetics 199 (2015) 39–59.
2015 | Journal Article | IST-REx-ID: 1940 |

Optimizing information flow in small genetic networks. IV. Spatial coupling
T.R. Sokolowski, G. Tkačik, Physical Review E Statistical Nonlinear and Soft Matter Physics 91 (2015).
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T.R. Sokolowski, G. Tkačik, Physical Review E Statistical Nonlinear and Soft Matter Physics 91 (2015).
2015 | Journal Article | IST-REx-ID: 1576 |

Stochastic proofreading mechanism alleviates crosstalk in transcriptional regulation
S.A. Cepeda Humerez, G. Rieckh, G. Tkačik, Physical Review Letters 115 (2015).
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S.A. Cepeda Humerez, G. Rieckh, G. Tkačik, Physical Review Letters 115 (2015).
2014 | Conference Paper | IST-REx-ID: 1708
Spatio-temporal representations of uncertainty in spiking neural networks
C. Savin, S. Denève, in:, Neural Information Processing Systems, 2014, pp. 2024–2032.
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C. Savin, S. Denève, in:, Neural Information Processing Systems, 2014, pp. 2024–2032.
2014 | Journal Article | IST-REx-ID: 1886 |

Variance predicts salience in central sensory processing
A. Hermundstad, J. Briguglio, M. Conte, J. Victor, V. Balasubramanian, G. Tkačik, ELife (2014).
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A. Hermundstad, J. Briguglio, M. Conte, J. Victor, V. Balasubramanian, G. Tkačik, ELife (2014).
2014 | Journal Article | IST-REx-ID: 1896 |

Mathematical model of alternative mechanism of telomere length maintenance
R. Kollár, K. Bod’ová, J. Nosek, Ľ. Tomáška, Physical Review E Statistical Nonlinear and Soft Matter Physics 89 (2014).
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R. Kollár, K. Bod’ová, J. Nosek, Ľ. Tomáška, Physical Review E Statistical Nonlinear and Soft Matter Physics 89 (2014).
2014 | Journal Article | IST-REx-ID: 1928
Evolutionary dynamics of infectious diseases in finite populations
J. Humplik, A. Hill, M. Nowak, Journal of Theoretical Biology 360 (2014) 149–162.
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J. Humplik, A. Hill, M. Nowak, Journal of Theoretical Biology 360 (2014) 149–162.
2014 | Journal Article | IST-REx-ID: 1931 |

Emergence of task-dependent representations in working memory circuits
C. Savin, J. Triesch, Frontiers in Computational Neuroscience 8 (2014).
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C. Savin, J. Triesch, Frontiers in Computational Neuroscience 8 (2014).
2014 | Journal Article | IST-REx-ID: 1909 |

The fitness costs of adaptation via phenotypic plasticity and maternal effects
T. Ezard, R. Prizak, R. Hoyle, Functional Ecology 28 (2014) 693–701.
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T. Ezard, R. Prizak, R. Hoyle, Functional Ecology 28 (2014) 693–701.
2014 | Journal Article | IST-REx-ID: 2231 |

Noise and information transmission in promoters with multiple internal states
G. Rieckh, G. Tkačik, Biophysical Journal 106 (2014) 1194–1204.
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| PubMed | Europe PMC
G. Rieckh, G. Tkačik, Biophysical Journal 106 (2014) 1194–1204.
2014 | Journal Article | IST-REx-ID: 3263 |

Adaptation to changes in higher-order stimulus statistics in the salamander retina
G. Tkačik, A. Ghosh, E. Schneidman, R. Segev, PLoS One 9 (2014).
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G. Tkačik, A. Ghosh, E. Schneidman, R. Segev, PLoS One 9 (2014).
2014 | Journal Article | IST-REx-ID: 537 |

Fitness consequences of maternal and grandmaternal effects
R. Prizak, T. Ezard, R. Hoyle, Ecology and Evolution 4 (2014) 3139–3145.
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R. Prizak, T. Ezard, R. Hoyle, Ecology and Evolution 4 (2014) 3139–3145.
2014 | Journal Article | IST-REx-ID: 2257 |

Searching for collective behavior in a large network of sensory neurons
G. Tkačik, O. Marre, D. Amodei, E. Schneidman, W. Bialek, M. Berry, PLoS Computational Biology 10 (2014).
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G. Tkačik, O. Marre, D. Amodei, E. Schneidman, W. Bialek, M. Berry, PLoS Computational Biology 10 (2014).
2013 | Journal Article | IST-REx-ID: 2277 |

Transformation of stimulus correlations by the retina
K. Simmons, J. Prentice, G. Tkačik, J. Homann, H. Yee, S. Palmer, P. Nelson, V. Balasubramanian, PLoS Computational Biology 9 (2013).
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K. Simmons, J. Prentice, G. Tkačik, J. Homann, H. Yee, S. Palmer, P. Nelson, V. Balasubramanian, PLoS Computational Biology 9 (2013).
2013 | Book Chapter | IST-REx-ID: 2413
Neuronal oscillations scale up and scale down the brain dynamics
M. Valderrama, V. Botella Soler, M. Le Van Quyen, in:, M. Meyer, Z. Pesenson (Eds.), Multiscale Analysis and Nonlinear Dynamics: From Genes to the Brain, Wiley-VCH, 2013.
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M. Valderrama, V. Botella Soler, M. Le Van Quyen, in:, M. Meyer, Z. Pesenson (Eds.), Multiscale Analysis and Nonlinear Dynamics: From Genes to the Brain, Wiley-VCH, 2013.
2013 | Journal Article | IST-REx-ID: 2818 |

Learning quadratic receptive fields from neural responses to natural stimuli
K. Rajan, O. Marre, G. Tkačik, Neural Computation 25 (2013) 1661–1692.
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| arXiv
K. Rajan, O. Marre, G. Tkačik, Neural Computation 25 (2013) 1661–1692.
2013 | Journal Article | IST-REx-ID: 2861
Lyapunov exponent and topological entropy plateaus in piecewise linear maps
V. Botella Soler, J. Oteo, J. Ros, P. Glendinning, Journal of Physics A: Mathematical and Theoretical 46 (2013).
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V. Botella Soler, J. Oteo, J. Ros, P. Glendinning, Journal of Physics A: Mathematical and Theoretical 46 (2013).
2013 | Journal Article | IST-REx-ID: 2863 |

Stimulus-dependent maximum entropy models of neural population codes
E. Granot Atedgi, G. Tkačik, R. Segev, E. Schneidman, PLoS Computational Biology 9 (2013).
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E. Granot Atedgi, G. Tkačik, R. Segev, E. Schneidman, PLoS Computational Biology 9 (2013).
2013 | Journal Article | IST-REx-ID: 2913 |

Retinal metric: a stimulus distance measure derived from population neural responses
G. Tkačik, E. Granot Atedgi, R. Segev, E. Schneidman, Physical Review Letters 110 (2013).
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G. Tkačik, E. Granot Atedgi, R. Segev, E. Schneidman, Physical Review Letters 110 (2013).
2013 | Journal Article | IST-REx-ID: 2914 |

Statistical thermodynamics of natural images
G. Stephens, T. Mora, G. Tkačik, W. Bialek, Physical Review Letters 110 (2013).
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| arXiv
G. Stephens, T. Mora, G. Tkačik, W. Bialek, Physical Review Letters 110 (2013).
2013 | Journal Article | IST-REx-ID: 2850 |

The simplest maximum entropy model for collective behavior in a neural network
G. Tkačik, O. Marre, T. Mora, D. Amodei, M. Berry, W. Bialek, Journal of Statistical Mechanics Theory and Experiment 2013 (2013).
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| arXiv
G. Tkačik, O. Marre, T. Mora, D. Amodei, M. Berry, W. Bialek, Journal of Statistical Mechanics Theory and Experiment 2013 (2013).
2013 | Journal Article | IST-REx-ID: 2851
A simple method for estimating the entropy of neural activity
M. Berry, G. Tkačik, J. Dubuis, O. Marre, R. Da Silveira, Journal of Statistical Mechanics Theory and Experiment 2013 (2013).
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| DOI
M. Berry, G. Tkačik, J. Dubuis, O. Marre, R. Da Silveira, Journal of Statistical Mechanics Theory and Experiment 2013 (2013).
2013 | Journal Article | IST-REx-ID: 3261 |

Positional information, in bits
J. Dubuis, G. Tkačik, E. Wieschaus, T. Gregor, W. Bialek, PNAS 110 (2013) 16301–16308.
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J. Dubuis, G. Tkačik, E. Wieschaus, T. Gregor, W. Bialek, PNAS 110 (2013) 16301–16308.
2013 | Journal Article | IST-REx-ID: 499
Dynamic persistence of antibiotic-stressed mycobacteria
Y. Wakamoto, N. Dhar, R.P. Chait, K. Schneider, F. Signorino Gelo, S. Leibler, J. Mckinney, Science 339 (2013) 91–95.
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Y. Wakamoto, N. Dhar, R.P. Chait, K. Schneider, F. Signorino Gelo, S. Leibler, J. Mckinney, Science 339 (2013) 91–95.
2012 | Journal Article | IST-REx-ID: 3262 |

Optimizing information flow in small genetic networks. III. A self-interacting gene
G. Tkačik, A. Walczak, W. Bialek, Physical Review E Statistical Nonlinear and Soft Matter Physics 85 (2012).
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G. Tkačik, A. Walczak, W. Bialek, Physical Review E Statistical Nonlinear and Soft Matter Physics 85 (2012).
2012 | Journal Article | IST-REx-ID: 3274
A 2.5D-Fourier-BEM model for vibrations in a tunnel running through layered anisotropic soil
G. Rieckh, W. Kreuzer, H. Waubke, P. Balazs, Engineering Analysis with Boundary Elements 36 (2012) 960–967.
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G. Rieckh, W. Kreuzer, H. Waubke, P. Balazs, Engineering Analysis with Boundary Elements 36 (2012) 960–967.
2011 | Journal Article | IST-REx-ID: 3384 |

Natural images from the birthplace of the human eye
G. Tkačik, P. Garrigan, C. Ratliff, G. Milcinski, J. Klein, L. Seyfarth, P. Sterling, D. Brainard, V. Balasubramanian, PLoS One 6 (2011).
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G. Tkačik, P. Garrigan, C. Ratliff, G. Milcinski, J. Klein, L. Seyfarth, P. Sterling, D. Brainard, V. Balasubramanian, PLoS One 6 (2011).
2011 | Journal Article | IST-REx-ID: 3374 |

Information transmission in genetic regulatory networks a review
G. Tkačik, A. Walczak, Journal of Physics: Condensed Matter 23 (2011).
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G. Tkačik, A. Walczak, Journal of Physics: Condensed Matter 23 (2011).