---
_id: '14795'
abstract:
- lang: eng
text: Metazoan development relies on the formation and remodeling of cell-cell contacts.
Dynamic reorganization of adhesion receptors and the actomyosin cell cortex in
space and time plays a central role in cell-cell contact formation and maturation.
Nevertheless, how this process is mechanistically achieved when new contacts are
formed remains unclear. Here, by building a biomimetic assay composed of progenitor
cells adhering to supported lipid bilayers functionalized with E-cadherin ectodomains,
we show that cortical F-actin flows, driven by the depletion of myosin-2 at the
cell contact center, mediate the dynamic reorganization of adhesion receptors
and cell cortex at the contact. E-cadherin-dependent downregulation of the small
GTPase RhoA at the forming contact leads to both a depletion of myosin-2 and a
decrease of F-actin at the contact center. At the contact rim, in contrast, myosin-2
becomes enriched by the retraction of bleb-like protrusions, resulting in a cortical
tension gradient from the contact rim to its center. This tension gradient, in
turn, triggers centrifugal F-actin flows, leading to further accumulation of F-actin
at the contact rim and the progressive redistribution of E-cadherin from the contact
center to the rim. Eventually, this combination of actomyosin downregulation and
flows at the contact determines the characteristic molecular organization, with
E-cadherin and F-actin accumulating at the contact rim, where they are needed
to mechanically link the contractile cortices of the adhering cells.
acknowledged_ssus:
- _id: Bio
- _id: PreCl
acknowledgement: "We are grateful to Edwin Munro for their feedback and help with
the single particle analysis. We thank members of the Heisenberg and Loose labs
for their help and feedback on the manuscript, notably Xin Tong for making the PCS2-mCherry-AHPH
plasmid. Finally, we thank the Aquatics and Imaging & Optics facilities of ISTA
for their continuous support, especially Yann Cesbron for assistance with the laser
cutter. This work was supported by an ERC\r\nAdvanced Grant (MECSPEC) to C.-P.H."
article_processing_charge: Yes (via OA deal)
article_type: original
author:
- first_name: Feyza N
full_name: Arslan, Feyza N
id: 49DA7910-F248-11E8-B48F-1D18A9856A87
last_name: Arslan
orcid: 0000-0001-5809-9566
- first_name: Edouard B
full_name: Hannezo, Edouard B
id: 3A9DB764-F248-11E8-B48F-1D18A9856A87
last_name: Hannezo
orcid: 0000-0001-6005-1561
- first_name: Jack
full_name: Merrin, Jack
id: 4515C308-F248-11E8-B48F-1D18A9856A87
last_name: Merrin
orcid: 0000-0001-5145-4609
- first_name: Martin
full_name: Loose, Martin
id: 462D4284-F248-11E8-B48F-1D18A9856A87
last_name: Loose
orcid: 0000-0001-7309-9724
- first_name: Carl-Philipp J
full_name: Heisenberg, Carl-Philipp J
id: 39427864-F248-11E8-B48F-1D18A9856A87
last_name: Heisenberg
orcid: 0000-0002-0912-4566
citation:
ama: Arslan FN, Hannezo EB, Merrin J, Loose M, Heisenberg C-PJ. Adhesion-induced
cortical flows pattern E-cadherin-mediated cell contacts. Current Biology.
2024;34(1):171-182.e8. doi:10.1016/j.cub.2023.11.067
apa: Arslan, F. N., Hannezo, E. B., Merrin, J., Loose, M., & Heisenberg, C.-P.
J. (2024). Adhesion-induced cortical flows pattern E-cadherin-mediated cell contacts.
Current Biology. Elsevier. https://doi.org/10.1016/j.cub.2023.11.067
chicago: Arslan, Feyza N, Edouard B Hannezo, Jack Merrin, Martin Loose, and Carl-Philipp
J Heisenberg. “Adhesion-Induced Cortical Flows Pattern E-Cadherin-Mediated Cell
Contacts.” Current Biology. Elsevier, 2024. https://doi.org/10.1016/j.cub.2023.11.067.
ieee: F. N. Arslan, E. B. Hannezo, J. Merrin, M. Loose, and C.-P. J. Heisenberg,
“Adhesion-induced cortical flows pattern E-cadherin-mediated cell contacts,” Current
Biology, vol. 34, no. 1. Elsevier, p. 171–182.e8, 2024.
ista: Arslan FN, Hannezo EB, Merrin J, Loose M, Heisenberg C-PJ. 2024. Adhesion-induced
cortical flows pattern E-cadherin-mediated cell contacts. Current Biology. 34(1),
171–182.e8.
mla: Arslan, Feyza N., et al. “Adhesion-Induced Cortical Flows Pattern E-Cadherin-Mediated
Cell Contacts.” Current Biology, vol. 34, no. 1, Elsevier, 2024, p. 171–182.e8,
doi:10.1016/j.cub.2023.11.067.
short: F.N. Arslan, E.B. Hannezo, J. Merrin, M. Loose, C.-P.J. Heisenberg, Current
Biology 34 (2024) 171–182.e8.
date_created: 2024-01-14T23:00:56Z
date_published: 2024-01-08T00:00:00Z
date_updated: 2024-01-17T08:20:40Z
day: '08'
ddc:
- '570'
department:
- _id: CaHe
- _id: EdHa
- _id: MaLo
- _id: NanoFab
doi: 10.1016/j.cub.2023.11.067
ec_funded: 1
file:
- access_level: open_access
checksum: 51220b76d72a614208f84bdbfbaf9b72
content_type: application/pdf
creator: dernst
date_created: 2024-01-16T10:53:31Z
date_updated: 2024-01-16T10:53:31Z
file_id: '14813'
file_name: 2024_CurrentBiology_Arslan.pdf
file_size: 5183861
relation: main_file
success: 1
file_date_updated: 2024-01-16T10:53:31Z
has_accepted_license: '1'
intvolume: ' 34'
issue: '1'
language:
- iso: eng
month: '01'
oa: 1
oa_version: Published Version
page: 171-182.e8
project:
- _id: 260F1432-B435-11E9-9278-68D0E5697425
call_identifier: H2020
grant_number: '742573'
name: Interaction and feedback between cell mechanics and fate specification in
vertebrate gastrulation
publication: Current Biology
publication_identifier:
eissn:
- 1879-0445
issn:
- 0960-9822
publication_status: published
publisher: Elsevier
quality_controlled: '1'
scopus_import: '1'
status: public
title: Adhesion-induced cortical flows pattern E-cadherin-mediated cell contacts
tmp:
image: /images/cc_by.png
legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
short: CC BY (4.0)
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 34
year: '2024'
...
---
_id: '15048'
abstract:
- lang: eng
text: Embryogenesis results from the coordinated activities of different signaling
pathways controlling cell fate specification and morphogenesis. In vertebrate
gastrulation, both Nodal and BMP signaling play key roles in germ layer specification
and morphogenesis, yet their interplay to coordinate embryo patterning with morphogenesis
is still insufficiently understood. Here, we took a reductionist approach using
zebrafish embryonic explants to study the coordination of Nodal and BMP signaling
for embryo patterning and morphogenesis. We show that Nodal signaling triggers
explant elongation by inducing mesendodermal progenitors but also suppressing
BMP signaling activity at the site of mesendoderm induction. Consistent with this,
ectopic BMP signaling in the mesendoderm blocks cell alignment and oriented mesendoderm
intercalations, key processes during explant elongation. Translating these ex
vivo observations to the intact embryo showed that, similar to explants, Nodal
signaling suppresses the effect of BMP signaling on cell intercalations in the
dorsal domain, thus allowing robust embryonic axis elongation. These findings
suggest a dual function of Nodal signaling in embryonic axis elongation by both
inducing mesendoderm and suppressing BMP effects in the dorsal portion of the
mesendoderm.
acknowledged_ssus:
- _id: Bio
- _id: LifeSc
acknowledgement: "We thank Patrick Müller for sharing the chordintt250 mutant zebrafish
line as well as the plasmid for chrd-GFP, Katherine Rogers for sharing the bmp2b
plasmid and Andrea Pauli for sharing the draculin plasmid. Diana Pinheiro generated
the MZlefty1,2;Tg(sebox::EGFP) line. We are grateful to Patrick Müller, Diana Pinheiro
and Katherine Rogers and members of the Heisenberg lab for discussions, technical
advice and feedback on the manuscript. We also thank Anna Kicheva and Edouard Hannezo
for discussions. We thank the Imaging and Optics Facility as well as the Life Science
facility at IST Austria for support with microscopy and fish maintenance.\r\nThis
work was supported by a European Research Council Advanced Grant\r\n(MECSPEC 742573
to C.-P.H.). A.S. is a recipient of a DOC Fellowship of the Austrian\r\nAcademy
of Sciences at IST Austria. Open Access funding provided by Institute of\r\nScience
and Technology Austria. "
article_processing_charge: Yes (via OA deal)
article_type: original
author:
- first_name: Alexandra
full_name: Schauer, Alexandra
id: 30A536BA-F248-11E8-B48F-1D18A9856A87
last_name: Schauer
orcid: 0000-0001-7659-9142
- first_name: Kornelija
full_name: Pranjic-Ferscha, Kornelija
id: 4362B3C2-F248-11E8-B48F-1D18A9856A87
last_name: Pranjic-Ferscha
- first_name: Robert
full_name: Hauschild, Robert
id: 4E01D6B4-F248-11E8-B48F-1D18A9856A87
last_name: Hauschild
orcid: 0000-0001-9843-3522
- first_name: Carl-Philipp J
full_name: Heisenberg, Carl-Philipp J
id: 39427864-F248-11E8-B48F-1D18A9856A87
last_name: Heisenberg
orcid: 0000-0002-0912-4566
citation:
ama: Schauer A, Pranjic-Ferscha K, Hauschild R, Heisenberg C-PJ. Robust axis elongation
by Nodal-dependent restriction of BMP signaling. Development. 2024;151(4):1-18.
doi:10.1242/dev.202316
apa: Schauer, A., Pranjic-Ferscha, K., Hauschild, R., & Heisenberg, C.-P. J.
(2024). Robust axis elongation by Nodal-dependent restriction of BMP signaling.
Development. The Company of Biologists. https://doi.org/10.1242/dev.202316
chicago: Schauer, Alexandra, Kornelija Pranjic-Ferscha, Robert Hauschild, and Carl-Philipp
J Heisenberg. “Robust Axis Elongation by Nodal-Dependent Restriction of BMP Signaling.”
Development. The Company of Biologists, 2024. https://doi.org/10.1242/dev.202316.
ieee: A. Schauer, K. Pranjic-Ferscha, R. Hauschild, and C.-P. J. Heisenberg, “Robust
axis elongation by Nodal-dependent restriction of BMP signaling,” Development,
vol. 151, no. 4. The Company of Biologists, pp. 1–18, 2024.
ista: Schauer A, Pranjic-Ferscha K, Hauschild R, Heisenberg C-PJ. 2024. Robust axis
elongation by Nodal-dependent restriction of BMP signaling. Development. 151(4),
1–18.
mla: Schauer, Alexandra, et al. “Robust Axis Elongation by Nodal-Dependent Restriction
of BMP Signaling.” Development, vol. 151, no. 4, The Company of Biologists,
2024, pp. 1–18, doi:10.1242/dev.202316.
short: A. Schauer, K. Pranjic-Ferscha, R. Hauschild, C.-P.J. Heisenberg, Development
151 (2024) 1–18.
date_created: 2024-03-03T23:00:50Z
date_published: 2024-02-01T00:00:00Z
date_updated: 2024-03-04T07:28:25Z
day: '01'
ddc:
- '570'
department:
- _id: CaHe
- _id: Bio
doi: 10.1242/dev.202316
ec_funded: 1
file:
- access_level: open_access
checksum: 6961ea10012bf0d266681f9628bb8f13
content_type: application/pdf
creator: dernst
date_created: 2024-03-04T07:24:43Z
date_updated: 2024-03-04T07:24:43Z
file_id: '15050'
file_name: 2024_Development_Schauer.pdf
file_size: 14839986
relation: main_file
success: 1
file_date_updated: 2024-03-04T07:24:43Z
has_accepted_license: '1'
intvolume: ' 151'
issue: '4'
language:
- iso: eng
month: '02'
oa: 1
oa_version: Published Version
page: 1-18
project:
- _id: 260F1432-B435-11E9-9278-68D0E5697425
call_identifier: H2020
grant_number: '742573'
name: Interaction and feedback between cell mechanics and fate specification in
vertebrate gastrulation
- _id: 26B1E39C-B435-11E9-9278-68D0E5697425
grant_number: '25239'
name: 'Mesendoderm specification in zebrafish: The role of extraembryonic tissues'
publication: Development
publication_identifier:
eissn:
- 1477-9129
issn:
- 0950-1991
publication_status: published
publisher: The Company of Biologists
quality_controlled: '1'
related_material:
record:
- id: '14926'
relation: research_data
status: public
scopus_import: '1'
status: public
title: Robust axis elongation by Nodal-dependent restriction of BMP signaling
tmp:
image: /images/cc_by.png
legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
short: CC BY (4.0)
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 151
year: '2024'
...
---
_id: '14846'
abstract:
- lang: eng
text: Contraction and flow of the actin cell cortex have emerged as a common principle
by which cells reorganize their cytoplasm and take shape. However, how these cortical
flows interact with adjacent cytoplasmic components, changing their form and localization,
and how this affects cytoplasmic organization and cell shape remains unclear.
Here we show that in ascidian oocytes, the cooperative activities of cortical
actomyosin flows and deformation of the adjacent mitochondria-rich myoplasm drive
oocyte cytoplasmic reorganization and shape changes following fertilization. We
show that vegetal-directed cortical actomyosin flows, established upon oocyte
fertilization, lead to both the accumulation of cortical actin at the vegetal
pole of the zygote and compression and local buckling of the adjacent elastic
solid-like myoplasm layer due to friction forces generated at their interface.
Once cortical flows have ceased, the multiple myoplasm buckles resolve into one
larger buckle, which again drives the formation of the contraction pole—a protuberance
of the zygote’s vegetal pole where maternal mRNAs accumulate. Thus, our findings
reveal a mechanism where cortical actomyosin network flows determine cytoplasmic
reorganization and cell shape by deforming adjacent cytoplasmic components through
friction forces.
acknowledged_ssus:
- _id: EM-Fac
- _id: Bio
- _id: NanoFab
acknowledgement: We would like to thank A. McDougall, E. Hannezo and the Heisenberg
lab for fruitful discussions and reagents. We also thank E. Munro for the iMyo-YFP
and Bra>iMyo-mScarlet constructs. This research was supported by the Scientific
Service Units of the Institute of Science and Technology Austria through resources
provided by the Electron Microscopy Facility, Imaging and Optics Facility and the
Nanofabrication Facility. This work was supported by a Joint Project Grant from
the FWF (I 3601-B27).
article_processing_charge: Yes (in subscription journal)
article_type: original
author:
- first_name: Silvia
full_name: Caballero Mancebo, Silvia
id: 2F1E1758-F248-11E8-B48F-1D18A9856A87
last_name: Caballero Mancebo
orcid: 0000-0002-5223-3346
- first_name: Rushikesh
full_name: Shinde, Rushikesh
last_name: Shinde
- first_name: Madison
full_name: Bolger-Munro, Madison
id: 516F03FA-93A3-11EA-A7C5-D6BE3DDC885E
last_name: Bolger-Munro
orcid: 0000-0002-8176-4824
- first_name: Matilda
full_name: Peruzzo, Matilda
id: 3F920B30-F248-11E8-B48F-1D18A9856A87
last_name: Peruzzo
orcid: 0000-0002-3415-4628
- first_name: Gregory
full_name: Szep, Gregory
id: 4BFB7762-F248-11E8-B48F-1D18A9856A87
last_name: Szep
- first_name: Irene
full_name: Steccari, Irene
id: 2705C766-9FE2-11EA-B224-C6773DDC885E
last_name: Steccari
- first_name: David
full_name: Labrousse Arias, David
id: CD573DF4-9ED3-11E9-9D77-3223E6697425
last_name: Labrousse Arias
- first_name: Vanessa
full_name: Zheden, Vanessa
id: 39C5A68A-F248-11E8-B48F-1D18A9856A87
last_name: Zheden
orcid: 0000-0002-9438-4783
- first_name: Jack
full_name: Merrin, Jack
id: 4515C308-F248-11E8-B48F-1D18A9856A87
last_name: Merrin
orcid: 0000-0001-5145-4609
- first_name: Andrew
full_name: Callan-Jones, Andrew
last_name: Callan-Jones
- first_name: Raphaël
full_name: Voituriez, Raphaël
last_name: Voituriez
- first_name: Carl-Philipp J
full_name: Heisenberg, Carl-Philipp J
id: 39427864-F248-11E8-B48F-1D18A9856A87
last_name: Heisenberg
orcid: 0000-0002-0912-4566
citation:
ama: Caballero Mancebo S, Shinde R, Bolger-Munro M, et al. Friction forces determine
cytoplasmic reorganization and shape changes of ascidian oocytes upon fertilization.
Nature Physics. 2024. doi:10.1038/s41567-023-02302-1
apa: Caballero Mancebo, S., Shinde, R., Bolger-Munro, M., Peruzzo, M., Szep, G.,
Steccari, I., … Heisenberg, C.-P. J. (2024). Friction forces determine cytoplasmic
reorganization and shape changes of ascidian oocytes upon fertilization. Nature
Physics. Springer Nature. https://doi.org/10.1038/s41567-023-02302-1
chicago: Caballero Mancebo, Silvia, Rushikesh Shinde, Madison Bolger-Munro, Matilda
Peruzzo, Gregory Szep, Irene Steccari, David Labrousse Arias, et al. “Friction
Forces Determine Cytoplasmic Reorganization and Shape Changes of Ascidian Oocytes
upon Fertilization.” Nature Physics. Springer Nature, 2024. https://doi.org/10.1038/s41567-023-02302-1.
ieee: S. Caballero Mancebo et al., “Friction forces determine cytoplasmic
reorganization and shape changes of ascidian oocytes upon fertilization,” Nature
Physics. Springer Nature, 2024.
ista: Caballero Mancebo S, Shinde R, Bolger-Munro M, Peruzzo M, Szep G, Steccari
I, Labrousse Arias D, Zheden V, Merrin J, Callan-Jones A, Voituriez R, Heisenberg
C-PJ. 2024. Friction forces determine cytoplasmic reorganization and shape changes
of ascidian oocytes upon fertilization. Nature Physics.
mla: Caballero Mancebo, Silvia, et al. “Friction Forces Determine Cytoplasmic Reorganization
and Shape Changes of Ascidian Oocytes upon Fertilization.” Nature Physics,
Springer Nature, 2024, doi:10.1038/s41567-023-02302-1.
short: S. Caballero Mancebo, R. Shinde, M. Bolger-Munro, M. Peruzzo, G. Szep, I.
Steccari, D. Labrousse Arias, V. Zheden, J. Merrin, A. Callan-Jones, R. Voituriez,
C.-P.J. Heisenberg, Nature Physics (2024).
date_created: 2024-01-21T23:00:57Z
date_published: 2024-01-09T00:00:00Z
date_updated: 2024-03-05T09:33:38Z
day: '09'
department:
- _id: CaHe
- _id: JoFi
- _id: MiSi
- _id: EM-Fac
- _id: NanoFab
doi: 10.1038/s41567-023-02302-1
has_accepted_license: '1'
language:
- iso: eng
main_file_link:
- open_access: '1'
url: https://doi.org/10.1038/s41567-023-02302-1
month: '01'
oa: 1
oa_version: Published Version
project:
- _id: 2646861A-B435-11E9-9278-68D0E5697425
call_identifier: FWF
grant_number: I03601
name: Control of embryonic cleavage pattern
publication: Nature Physics
publication_identifier:
eissn:
- 1745-2481
issn:
- 1745-2473
publication_status: epub_ahead
publisher: Springer Nature
quality_controlled: '1'
related_material:
link:
- description: News on ISTA Website
relation: press_release
url: https://ista.ac.at/en/news/stranger-than-friction-a-force-initiating-life/
scopus_import: '1'
status: public
title: Friction forces determine cytoplasmic reorganization and shape changes of ascidian
oocytes upon fertilization
tmp:
image: /images/cc_by.png
legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
short: CC BY (4.0)
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
year: '2024'
...
---
_id: '12830'
abstract:
- lang: eng
text: Interstitial fluid (IF) accumulation between embryonic cells is thought to
be important for embryo patterning and morphogenesis. Here, we identify a positive
mechanical feedback loop between cell migration and IF relocalization and find
that it promotes embryonic axis formation during zebrafish gastrulation. We show
that anterior axial mesendoderm (prechordal plate [ppl]) cells, moving in between
the yolk cell and deep cell tissue to extend the embryonic axis, compress the
overlying deep cell layer, thereby causing IF to flow from the deep cell layer
to the boundary between the yolk cell and the deep cell layer, directly ahead
of the advancing ppl. This IF relocalization, in turn, facilitates ppl cell protrusion
formation and migration by opening up the space into which the ppl moves and,
thereby, the ability of the ppl to trigger IF relocalization by pushing against
the overlying deep cell layer. Thus, embryonic axis formation relies on a hydraulic
feedback loop between cell migration and IF relocalization.
acknowledged_ssus:
- _id: PreCl
- _id: Bio
acknowledgement: We thank Andrea Pauli (IMP) and Edouard Hannezo (ISTA) for fruitful
discussions and support with the SPIM experiments; the Heisenberg group, and especially
Feyza Nur Arslan and Alexandra Schauer, for discussions and feedback; Michaela Jović
(ISTA) for help with the quantitative real-time PCR protocol; the bioimaging and
zebrafish facilities of ISTA for continuous support; Stephan Preibisch (Janelia
Research Campus) for support with the SPIM data analysis; and Nobuhiro Nakamura
(Tokyo Institute of Technology) for sharing α1-Na+/K+-ATPase antibody. This work
was supported by funding from the European Union (European Research Council Advanced
grant 742573 to C.-P.H.), postdoctoral fellowships from EMBO (LTF-850-2017) and
HFSP (LT000429/2018-L2) to D.P., and a PhD fellowship from the Studienstiftung des
deutschen Volkes to F.P.
article_processing_charge: Yes (via OA deal)
article_type: original
author:
- first_name: Karla
full_name: Huljev, Karla
id: 44C6F6A6-F248-11E8-B48F-1D18A9856A87
last_name: Huljev
- first_name: Shayan
full_name: Shamipour, Shayan
id: 40B34FE2-F248-11E8-B48F-1D18A9856A87
last_name: Shamipour
- first_name: Diana C
full_name: Nunes Pinheiro, Diana C
id: 2E839F16-F248-11E8-B48F-1D18A9856A87
last_name: Nunes Pinheiro
orcid: 0000-0003-4333-7503
- first_name: Friedrich
full_name: Preusser, Friedrich
last_name: Preusser
- first_name: Irene
full_name: Steccari, Irene
id: 2705C766-9FE2-11EA-B224-C6773DDC885E
last_name: Steccari
- first_name: Christoph M
full_name: Sommer, Christoph M
id: 4DF26D8C-F248-11E8-B48F-1D18A9856A87
last_name: Sommer
orcid: 0000-0003-1216-9105
- first_name: Suyash
full_name: Naik, Suyash
id: 2C0B105C-F248-11E8-B48F-1D18A9856A87
last_name: Naik
orcid: 0000-0001-8421-5508
- first_name: Carl-Philipp J
full_name: Heisenberg, Carl-Philipp J
id: 39427864-F248-11E8-B48F-1D18A9856A87
last_name: Heisenberg
orcid: 0000-0002-0912-4566
citation:
ama: Huljev K, Shamipour S, Nunes Pinheiro DC, et al. A hydraulic feedback loop
between mesendoderm cell migration and interstitial fluid relocalization promotes
embryonic axis formation in zebrafish. Developmental Cell. 2023;58(7):582-596.e7.
doi:10.1016/j.devcel.2023.02.016
apa: Huljev, K., Shamipour, S., Nunes Pinheiro, D. C., Preusser, F., Steccari, I.,
Sommer, C. M., … Heisenberg, C.-P. J. (2023). A hydraulic feedback loop between
mesendoderm cell migration and interstitial fluid relocalization promotes embryonic
axis formation in zebrafish. Developmental Cell. Elsevier. https://doi.org/10.1016/j.devcel.2023.02.016
chicago: Huljev, Karla, Shayan Shamipour, Diana C Nunes Pinheiro, Friedrich Preusser,
Irene Steccari, Christoph M Sommer, Suyash Naik, and Carl-Philipp J Heisenberg.
“A Hydraulic Feedback Loop between Mesendoderm Cell Migration and Interstitial
Fluid Relocalization Promotes Embryonic Axis Formation in Zebrafish.” Developmental
Cell. Elsevier, 2023. https://doi.org/10.1016/j.devcel.2023.02.016.
ieee: K. Huljev et al., “A hydraulic feedback loop between mesendoderm cell
migration and interstitial fluid relocalization promotes embryonic axis formation
in zebrafish,” Developmental Cell, vol. 58, no. 7. Elsevier, p. 582–596.e7,
2023.
ista: Huljev K, Shamipour S, Nunes Pinheiro DC, Preusser F, Steccari I, Sommer CM,
Naik S, Heisenberg C-PJ. 2023. A hydraulic feedback loop between mesendoderm cell
migration and interstitial fluid relocalization promotes embryonic axis formation
in zebrafish. Developmental Cell. 58(7), 582–596.e7.
mla: Huljev, Karla, et al. “A Hydraulic Feedback Loop between Mesendoderm Cell Migration
and Interstitial Fluid Relocalization Promotes Embryonic Axis Formation in Zebrafish.”
Developmental Cell, vol. 58, no. 7, Elsevier, 2023, p. 582–596.e7, doi:10.1016/j.devcel.2023.02.016.
short: K. Huljev, S. Shamipour, D.C. Nunes Pinheiro, F. Preusser, I. Steccari, C.M.
Sommer, S. Naik, C.-P.J. Heisenberg, Developmental Cell 58 (2023) 582–596.e7.
date_created: 2023-04-16T22:01:07Z
date_published: 2023-04-10T00:00:00Z
date_updated: 2023-08-01T14:10:38Z
day: '10'
ddc:
- '570'
department:
- _id: CaHe
- _id: Bio
doi: 10.1016/j.devcel.2023.02.016
ec_funded: 1
external_id:
isi:
- '000982111800001'
file:
- access_level: open_access
checksum: c80ca2ebc241232aacdb5aa4b4c80957
content_type: application/pdf
creator: dernst
date_created: 2023-04-17T07:41:25Z
date_updated: 2023-04-17T07:41:25Z
file_id: '12842'
file_name: 2023_DevelopmentalCell_Huljev.pdf
file_size: 7925886
relation: main_file
success: 1
file_date_updated: 2023-04-17T07:41:25Z
has_accepted_license: '1'
intvolume: ' 58'
isi: 1
issue: '7'
language:
- iso: eng
month: '04'
oa: 1
oa_version: Published Version
page: 582-596.e7
project:
- _id: 260F1432-B435-11E9-9278-68D0E5697425
call_identifier: H2020
grant_number: '742573'
name: Interaction and feedback between cell mechanics and fate specification in
vertebrate gastrulation
- _id: 26520D1E-B435-11E9-9278-68D0E5697425
grant_number: ALTF 850-2017
name: Coordination of mesendoderm cell fate specification and internalization during
zebrafish gastrulation
- _id: 266BC5CE-B435-11E9-9278-68D0E5697425
grant_number: LT000429
name: Coordination of mesendoderm fate specification and internalization during
zebrafish gastrulation
publication: Developmental Cell
publication_identifier:
eissn:
- 1878-1551
issn:
- 1534-5807
publication_status: published
publisher: Elsevier
quality_controlled: '1'
scopus_import: '1'
status: public
title: A hydraulic feedback loop between mesendoderm cell migration and interstitial
fluid relocalization promotes embryonic axis formation in zebrafish
tmp:
image: /images/cc_by.png
legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
short: CC BY (4.0)
type: journal_article
user_id: 4359f0d1-fa6c-11eb-b949-802e58b17ae8
volume: 58
year: '2023'
...
---
_id: '13229'
abstract:
- lang: eng
text: Dynamic reorganization of the cytoplasm is key to many core cellular processes,
such as cell division, cell migration, and cell polarization. Cytoskeletal rearrangements
are thought to constitute the main drivers of cytoplasmic flows and reorganization.
In contrast, remarkably little is known about how dynamic changes in size and
shape of cell organelles affect cytoplasmic organization. Here, we show that within
the maturing zebrafish oocyte, the surface localization of exocytosis-competent
cortical granules (Cgs) upon germinal vesicle breakdown (GVBD) is achieved by
the combined activities of yolk granule (Yg) fusion and microtubule aster formation
and translocation. We find that Cgs are moved towards the oocyte surface through
radially outward cytoplasmic flows induced by Ygs fusing and compacting towards
the oocyte center in response to GVBD. We further show that vesicles decorated
with the small Rab GTPase Rab11, a master regulator of vesicular trafficking and
exocytosis, accumulate together with Cgs at the oocyte surface. This accumulation
is achieved by Rab11-positive vesicles being transported by acentrosomal microtubule
asters, the formation of which is induced by the release of CyclinB/Cdk1 upon
GVBD, and which display a net movement towards the oocyte surface by preferentially
binding to the oocyte actin cortex. We finally demonstrate that the decoration
of Cgs by Rab11 at the oocyte surface is needed for Cg exocytosis and subsequent
chorion elevation, a process central in egg activation. Collectively, these findings
unravel a yet unrecognized role of organelle fusion, functioning together with
cytoskeletal rearrangements, in orchestrating cytoplasmic organization during
oocyte maturation.
acknowledgement: This work was supported by funding from the European Union (European
Research Council Advanced grant 742573) to C.-P.H. The funders had no role in study
design, data collection and analysis, decision to publish, or preparation of the
manuscript.
article_processing_charge: No
article_type: original
author:
- first_name: Shayan
full_name: Shamipour, Shayan
id: 40B34FE2-F248-11E8-B48F-1D18A9856A87
last_name: Shamipour
- first_name: Laura
full_name: Hofmann, Laura
id: b88d43f2-dc74-11ea-a0a7-e41b7912e031
last_name: Hofmann
- first_name: Irene
full_name: Steccari, Irene
id: 2705C766-9FE2-11EA-B224-C6773DDC885E
last_name: Steccari
- first_name: Roland
full_name: Kardos, Roland
id: 4039350E-F248-11E8-B48F-1D18A9856A87
last_name: Kardos
- first_name: Carl-Philipp J
full_name: Heisenberg, Carl-Philipp J
id: 39427864-F248-11E8-B48F-1D18A9856A87
last_name: Heisenberg
orcid: 0000-0002-0912-4566
citation:
ama: Shamipour S, Hofmann L, Steccari I, Kardos R, Heisenberg C-PJ. Yolk granule
fusion and microtubule aster formation regulate cortical granule translocation
and exocytosis in zebrafish oocytes. PLoS Biology. 2023;21(6):e3002146.
doi:10.1371/journal.pbio.3002146
apa: Shamipour, S., Hofmann, L., Steccari, I., Kardos, R., & Heisenberg, C.-P.
J. (2023). Yolk granule fusion and microtubule aster formation regulate cortical
granule translocation and exocytosis in zebrafish oocytes. PLoS Biology.
Public Library of Science. https://doi.org/10.1371/journal.pbio.3002146
chicago: Shamipour, Shayan, Laura Hofmann, Irene Steccari, Roland Kardos, and Carl-Philipp
J Heisenberg. “Yolk Granule Fusion and Microtubule Aster Formation Regulate Cortical
Granule Translocation and Exocytosis in Zebrafish Oocytes.” PLoS Biology.
Public Library of Science, 2023. https://doi.org/10.1371/journal.pbio.3002146.
ieee: S. Shamipour, L. Hofmann, I. Steccari, R. Kardos, and C.-P. J. Heisenberg,
“Yolk granule fusion and microtubule aster formation regulate cortical granule
translocation and exocytosis in zebrafish oocytes,” PLoS Biology, vol.
21, no. 6. Public Library of Science, p. e3002146, 2023.
ista: Shamipour S, Hofmann L, Steccari I, Kardos R, Heisenberg C-PJ. 2023. Yolk
granule fusion and microtubule aster formation regulate cortical granule translocation
and exocytosis in zebrafish oocytes. PLoS Biology. 21(6), e3002146.
mla: Shamipour, Shayan, et al. “Yolk Granule Fusion and Microtubule Aster Formation
Regulate Cortical Granule Translocation and Exocytosis in Zebrafish Oocytes.”
PLoS Biology, vol. 21, no. 6, Public Library of Science, 2023, p. e3002146,
doi:10.1371/journal.pbio.3002146.
short: S. Shamipour, L. Hofmann, I. Steccari, R. Kardos, C.-P.J. Heisenberg, PLoS
Biology 21 (2023) e3002146.
date_created: 2023-07-16T22:01:09Z
date_published: 2023-06-08T00:00:00Z
date_updated: 2023-08-02T06:33:14Z
day: '08'
ddc:
- '570'
department:
- _id: CaHe
doi: 10.1371/journal.pbio.3002146
ec_funded: 1
external_id:
isi:
- '001003199100005'
pmid:
- '37289834'
file:
- access_level: open_access
checksum: 8e88cb0e5a6433a2f1939a9030bed384
content_type: application/pdf
creator: dernst
date_created: 2023-07-18T07:59:58Z
date_updated: 2023-07-18T07:59:58Z
file_id: '13246'
file_name: 2023_PloSBiology_Shamipour.pdf
file_size: 4431723
relation: main_file
success: 1
file_date_updated: 2023-07-18T07:59:58Z
has_accepted_license: '1'
intvolume: ' 21'
isi: 1
issue: '6'
language:
- iso: eng
month: '06'
oa: 1
oa_version: Published Version
page: e3002146
pmid: 1
project:
- _id: 260F1432-B435-11E9-9278-68D0E5697425
call_identifier: H2020
grant_number: '742573'
name: Interaction and feedback between cell mechanics and fate specification in
vertebrate gastrulation
publication: PLoS Biology
publication_identifier:
eissn:
- 1545-7885
publication_status: published
publisher: Public Library of Science
quality_controlled: '1'
scopus_import: '1'
status: public
title: Yolk granule fusion and microtubule aster formation regulate cortical granule
translocation and exocytosis in zebrafish oocytes
tmp:
image: /images/cc_by.png
legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
short: CC BY (4.0)
type: journal_article
user_id: 4359f0d1-fa6c-11eb-b949-802e58b17ae8
volume: 21
year: '2023'
...
---
_id: '12891'
abstract:
- lang: eng
text: "The tight spatiotemporal coordination of signaling activity determining embryo\r\npatterning
and the physical processes driving embryo morphogenesis renders\r\nembryonic development
robust, such that key developmental processes can unfold\r\nrelatively normally
even outside of the full embryonic context. For instance, embryonic\r\nstem cell
cultures can recapitulate the hallmarks of gastrulation, i.e. break symmetry\r\nleading
to germ layer formation and morphogenesis, in a very reduced environment.\r\nThis
leads to questions on specific contributions of embryo-specific features, such
as\r\nthe presence of extraembryonic tissues, which are inherently involved in
gastrulation\r\nin the full embryonic context. To address this, we established
zebrafish embryonic\r\nexplants without the extraembryonic yolk cell, an important
player as a signaling\r\nsource and for morphogenesis during gastrulation, as
a model of ex vivo development.\r\nWe found that dorsal-marginal determinants
are required and sufficient in these\r\nexplants to form and pattern all three
germ layers. However, formation of tissues,\r\nwhich require the highest Nodal-signaling
levels, is variable, demonstrating a\r\ncontribution of extraembryonic tissues
for reaching peak Nodal signaling levels.\r\nBlastoderm explants also undergo
gastrulation-like axis elongation. We found that this\r\nelongation movement shows
hallmarks of oriented mesendoderm cell intercalations\r\ntypically associated
with dorsal tissues in the intact embryo. These are disrupted by\r\nuniform upregulation
of BMP signaling activity and concomitant explant ventralization,\r\nsuggesting
that tight spatial control of BMP signaling is a prerequisite for explant\r\nmorphogenesis.
This control is achieved by Nodal signaling, which is critical for\r\neffectively
downregulating BMP signaling in the mesendoderm, highlighting that Nodal\r\nsignaling
is not only directly required for mesendoderm cell fate specification and\r\nmorphogenesis,
but also by maintaining low levels of BMP signaling at the dorsal side.\r\nCollectively,
we provide insights into the capacity and organization of signaling and\r\nmorphogenetic
domains to recapitulate features of zebrafish gastrulation outside of\r\nthe full
embryonic context."
acknowledged_ssus:
- _id: Bio
- _id: LifeSc
alternative_title:
- ISTA Thesis
article_processing_charge: No
author:
- first_name: Alexandra
full_name: Schauer, Alexandra
id: 30A536BA-F248-11E8-B48F-1D18A9856A87
last_name: Schauer
orcid: 0000-0001-7659-9142
citation:
ama: 'Schauer A. Mesendoderm formation in zebrafish gastrulation: The role of extraembryonic
tissues. 2023. doi:10.15479/at:ista:12891'
apa: 'Schauer, A. (2023). Mesendoderm formation in zebrafish gastrulation: The
role of extraembryonic tissues. Institute of Science and Technology Austria.
https://doi.org/10.15479/at:ista:12891'
chicago: 'Schauer, Alexandra. “Mesendoderm Formation in Zebrafish Gastrulation:
The Role of Extraembryonic Tissues.” Institute of Science and Technology Austria,
2023. https://doi.org/10.15479/at:ista:12891.'
ieee: 'A. Schauer, “Mesendoderm formation in zebrafish gastrulation: The role of
extraembryonic tissues,” Institute of Science and Technology Austria, 2023.'
ista: 'Schauer A. 2023. Mesendoderm formation in zebrafish gastrulation: The role
of extraembryonic tissues. Institute of Science and Technology Austria.'
mla: 'Schauer, Alexandra. Mesendoderm Formation in Zebrafish Gastrulation: The
Role of Extraembryonic Tissues. Institute of Science and Technology Austria,
2023, doi:10.15479/at:ista:12891.'
short: 'A. Schauer, Mesendoderm Formation in Zebrafish Gastrulation: The Role of
Extraembryonic Tissues, Institute of Science and Technology Austria, 2023.'
date_created: 2023-05-05T08:48:20Z
date_published: 2023-05-05T00:00:00Z
date_updated: 2023-08-21T06:25:48Z
day: '05'
ddc:
- '570'
degree_awarded: PhD
department:
- _id: GradSch
- _id: CaHe
doi: 10.15479/at:ista:12891
ec_funded: 1
file:
- access_level: closed
checksum: 59b0303dc483f40a96a610a90aab7ee9
content_type: application/pdf
creator: aschauer
date_created: 2023-05-05T13:01:14Z
date_updated: 2023-05-05T13:01:14Z
embargo: 2024-05-05
embargo_to: open_access
file_id: '12907'
file_name: Thesis_Schauer_final.pdf
file_size: 31434230
relation: main_file
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checksum: 25f54e12479b6adaabd129a20568e6c1
content_type: application/vnd.openxmlformats-officedocument.wordprocessingml.document
creator: aschauer
date_created: 2023-05-05T13:04:15Z
date_updated: 2023-05-05T13:04:15Z
file_id: '12908'
file_name: Thesis_Schauer_final.docx
file_size: 43809109
relation: source_file
file_date_updated: 2023-05-05T13:04:15Z
has_accepted_license: '1'
language:
- iso: eng
month: '05'
oa_version: Published Version
page: '190'
project:
- _id: 260F1432-B435-11E9-9278-68D0E5697425
call_identifier: H2020
grant_number: '742573'
name: Interaction and feedback between cell mechanics and fate specification in
vertebrate gastrulation
- _id: 26B1E39C-B435-11E9-9278-68D0E5697425
grant_number: '25239'
name: 'Mesendoderm specification in zebrafish: The role of extraembryonic tissues'
publication_identifier:
issn:
- 2663 - 337X
publication_status: published
publisher: Institute of Science and Technology Austria
related_material:
record:
- id: '8966'
relation: part_of_dissertation
status: public
- id: '7888'
relation: part_of_dissertation
status: public
status: public
supervisor:
- first_name: Carl-Philipp J
full_name: Heisenberg, Carl-Philipp J
id: 39427864-F248-11E8-B48F-1D18A9856A87
last_name: Heisenberg
orcid: 0000-0002-0912-4566
title: 'Mesendoderm formation in zebrafish gastrulation: The role of extraembryonic
tissues'
type: dissertation
user_id: 8b945eb4-e2f2-11eb-945a-df72226e66a9
year: '2023'
...
---
_id: '14041'
abstract:
- lang: eng
text: Tissue morphogenesis and patterning during development involve the segregation
of cell types. Segregation is driven by differential tissue surface tensions generated
by cell types through controlling cell-cell contact formation by regulating adhesion
and actomyosin contractility-based cellular cortical tensions. We use vertebrate
tissue cell types and zebrafish germ layer progenitors as in vitro models of 3-dimensional
heterotypic segregation and developed a quantitative analysis of their dynamics
based on 3D time-lapse microscopy. We show that general inhibition of actomyosin
contractility by the Rho kinase inhibitor Y27632 delays segregation. Cell type-specific
inhibition of non-muscle myosin2 activity by overexpression of myosin assembly
inhibitor S100A4 reduces tissue surface tension, manifested in decreased compaction
during aggregation and inverted geometry observed during segregation. The same
is observed when we express a constitutively active Rho kinase isoform to ubiquitously
keep actomyosin contractility high at cell-cell and cell-medium interfaces and
thus overriding the interface-specific regulation of cortical tensions. Tissue
surface tension regulation can become an effective tool in tissue engineering.
acknowledgement: "We thank Marton Gulyas (ELTE Eötvös University) for development
of videomicroscopy experiment manager and image analysis software. Authors are grateful
to Gabor Forgacs (University of Missouri) for critical reading of earlier versions
of this manuscript as well as to Zsuzsa Akos and Andras Czirok (ELTE Eötvös University)
for fruitful discussions. This work was supported by EU FP7, ERC COLLMOT Project
No 227878 to TV, the National Research Development and Innovation Fund of Hungary,
K119359 and also Project No 2018-1.2.1-NKP-2018-00005 to LN. This project has received
funding from the European Union’s Horizon 2020 research and innovation programme
under the Marie Sklodowska-Curie grant agreement No 955576. MV was supported by
the Ja´nos Bolyai Fellowship of the Hungarian Academy of Sciences.\r\nOpen access
funding provided by Eötvös Loránd University."
article_number: '817'
article_processing_charge: Yes
article_type: original
author:
- first_name: Elod
full_name: Méhes, Elod
last_name: Méhes
- first_name: Enys
full_name: Mones, Enys
last_name: Mones
- first_name: Máté
full_name: Varga, Máté
last_name: Varga
- first_name: Áron
full_name: Zsigmond, Áron
last_name: Zsigmond
- first_name: Beáta
full_name: Biri-Kovács, Beáta
last_name: Biri-Kovács
- first_name: László
full_name: Nyitray, László
last_name: Nyitray
- first_name: Vanessa
full_name: Barone, Vanessa
id: 419EECCC-F248-11E8-B48F-1D18A9856A87
last_name: Barone
orcid: 0000-0003-2676-3367
- first_name: Gabriel
full_name: Krens, Gabriel
id: 2B819732-F248-11E8-B48F-1D18A9856A87
last_name: Krens
orcid: 0000-0003-4761-5996
- first_name: Carl-Philipp J
full_name: Heisenberg, Carl-Philipp J
id: 39427864-F248-11E8-B48F-1D18A9856A87
last_name: Heisenberg
orcid: 0000-0002-0912-4566
- first_name: Tamás
full_name: Vicsek, Tamás
last_name: Vicsek
citation:
ama: Méhes E, Mones E, Varga M, et al. 3D cell segregation geometry and dynamics
are governed by tissue surface tension regulation. Communications Biology.
2023;6. doi:10.1038/s42003-023-05181-7
apa: Méhes, E., Mones, E., Varga, M., Zsigmond, Á., Biri-Kovács, B., Nyitray, L.,
… Vicsek, T. (2023). 3D cell segregation geometry and dynamics are governed by
tissue surface tension regulation. Communications Biology. Springer Nature.
https://doi.org/10.1038/s42003-023-05181-7
chicago: Méhes, Elod, Enys Mones, Máté Varga, Áron Zsigmond, Beáta Biri-Kovács,
László Nyitray, Vanessa Barone, Gabriel Krens, Carl-Philipp J Heisenberg, and
Tamás Vicsek. “3D Cell Segregation Geometry and Dynamics Are Governed by Tissue
Surface Tension Regulation.” Communications Biology. Springer Nature, 2023.
https://doi.org/10.1038/s42003-023-05181-7.
ieee: E. Méhes et al., “3D cell segregation geometry and dynamics are governed
by tissue surface tension regulation,” Communications Biology, vol. 6.
Springer Nature, 2023.
ista: Méhes E, Mones E, Varga M, Zsigmond Á, Biri-Kovács B, Nyitray L, Barone V,
Krens G, Heisenberg C-PJ, Vicsek T. 2023. 3D cell segregation geometry and dynamics
are governed by tissue surface tension regulation. Communications Biology. 6,
817.
mla: Méhes, Elod, et al. “3D Cell Segregation Geometry and Dynamics Are Governed
by Tissue Surface Tension Regulation.” Communications Biology, vol. 6,
817, Springer Nature, 2023, doi:10.1038/s42003-023-05181-7.
short: E. Méhes, E. Mones, M. Varga, Á. Zsigmond, B. Biri-Kovács, L. Nyitray, V.
Barone, G. Krens, C.-P.J. Heisenberg, T. Vicsek, Communications Biology 6 (2023).
date_created: 2023-08-13T22:01:13Z
date_published: 2023-08-04T00:00:00Z
date_updated: 2023-12-13T12:07:33Z
day: '04'
ddc:
- '570'
department:
- _id: CaHe
- _id: Bio
doi: 10.1038/s42003-023-05181-7
external_id:
isi:
- '001042544100001'
pmid:
- '37542157'
file:
- access_level: open_access
checksum: 1f9324f736bdbb76426b07736651c4cd
content_type: application/pdf
creator: dernst
date_created: 2023-08-14T07:17:36Z
date_updated: 2023-08-14T07:17:36Z
file_id: '14045'
file_name: 2023_CommBiology_Mehes.pdf
file_size: 10181997
relation: main_file
success: 1
file_date_updated: 2023-08-14T07:17:36Z
has_accepted_license: '1'
intvolume: ' 6'
isi: 1
language:
- iso: eng
month: '08'
oa: 1
oa_version: Published Version
pmid: 1
publication: Communications Biology
publication_identifier:
eissn:
- 2399-3642
publication_status: published
publisher: Springer Nature
quality_controlled: '1'
scopus_import: '1'
status: public
title: 3D cell segregation geometry and dynamics are governed by tissue surface tension
regulation
tmp:
image: /images/cc_by.png
legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
short: CC BY (4.0)
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 6
year: '2023'
...
---
_id: '14082'
abstract:
- lang: eng
text: Epithelial barrier function is commonly analyzed using transepithelial electrical
resistance, which measures ion flux across a monolayer, or by adding traceable
macromolecules and monitoring their passage across the monolayer. Although these
methods measure changes in global barrier function, they lack the sensitivity
needed to detect local or transient barrier breaches, and they do not reveal the
location of barrier leaks. Therefore, we previously developed a method that we
named the zinc-based ultrasensitive microscopic barrier assay (ZnUMBA), which
overcomes these limitations, allowing for detection of local tight junction leaks
with high spatiotemporal resolution. Here, we present expanded applications for
ZnUMBA. ZnUMBA can be used in Xenopus embryos to measure the dynamics of barrier
restoration and actin accumulation following laser injury. ZnUMBA can also be
effectively utilized in developing zebrafish embryos as well as cultured monolayers
of Madin–Darby canine kidney (MDCK) II epithelial cells. ZnUMBA is a powerful
and flexible method that, with minimal optimization, can be applied to multiple
systems to measure dynamic changes in barrier function with spatiotemporal precision.
acknowledged_ssus:
- _id: PreCl
- _id: Bio
acknowledgement: "The authors thank their respective lab members for feedback and
helpful discussions. We thank the bioimaging and zebrafish facilities of IST Austria
for their support.\r\nThis work was supported by the National Institutes of Health
[R01GM112794 to A.L.M.], by Grants-in-Aid for Scientific Research from the Japan
Society for the Promotion of Science [21K06156 to T.H.], by the Grant Program for
Biomedical Engineering Research from the Nakatani Foundation for Advancement of
Measuring Technologies in Biomedical Engineering [to T.H.] and by funding from the
European Research Council [advanced grant 742573 to C.-P.H.]. "
article_number: jcs260668
article_processing_charge: No
article_type: original
author:
- first_name: Tomohito
full_name: Higashi, Tomohito
last_name: Higashi
- first_name: Rachel E.
full_name: Stephenson, Rachel E.
last_name: Stephenson
- first_name: Cornelia
full_name: Schwayer, Cornelia
id: 3436488C-F248-11E8-B48F-1D18A9856A87
last_name: Schwayer
orcid: 0000-0001-5130-2226
- first_name: Karla
full_name: Huljev, Karla
id: 44C6F6A6-F248-11E8-B48F-1D18A9856A87
last_name: Huljev
- first_name: Atsuko Y.
full_name: Higashi, Atsuko Y.
last_name: Higashi
- first_name: Carl-Philipp J
full_name: Heisenberg, Carl-Philipp J
id: 39427864-F248-11E8-B48F-1D18A9856A87
last_name: Heisenberg
orcid: 0000-0002-0912-4566
- first_name: Hideki
full_name: Chiba, Hideki
last_name: Chiba
- first_name: Ann L.
full_name: Miller, Ann L.
last_name: Miller
citation:
ama: Higashi T, Stephenson RE, Schwayer C, et al. ZnUMBA - a live imaging method
to detect local barrier breaches. Journal of Cell Science. 2023;136(15).
doi:10.1242/jcs.260668
apa: Higashi, T., Stephenson, R. E., Schwayer, C., Huljev, K., Higashi, A. Y., Heisenberg,
C.-P. J., … Miller, A. L. (2023). ZnUMBA - a live imaging method to detect local
barrier breaches. Journal of Cell Science. The Company of Biologists. https://doi.org/10.1242/jcs.260668
chicago: Higashi, Tomohito, Rachel E. Stephenson, Cornelia Schwayer, Karla Huljev,
Atsuko Y. Higashi, Carl-Philipp J Heisenberg, Hideki Chiba, and Ann L. Miller.
“ZnUMBA - a Live Imaging Method to Detect Local Barrier Breaches.” Journal
of Cell Science. The Company of Biologists, 2023. https://doi.org/10.1242/jcs.260668.
ieee: T. Higashi et al., “ZnUMBA - a live imaging method to detect local
barrier breaches,” Journal of Cell Science, vol. 136, no. 15. The Company
of Biologists, 2023.
ista: Higashi T, Stephenson RE, Schwayer C, Huljev K, Higashi AY, Heisenberg C-PJ,
Chiba H, Miller AL. 2023. ZnUMBA - a live imaging method to detect local barrier
breaches. Journal of Cell Science. 136(15), jcs260668.
mla: Higashi, Tomohito, et al. “ZnUMBA - a Live Imaging Method to Detect Local Barrier
Breaches.” Journal of Cell Science, vol. 136, no. 15, jcs260668, The Company
of Biologists, 2023, doi:10.1242/jcs.260668.
short: T. Higashi, R.E. Stephenson, C. Schwayer, K. Huljev, A.Y. Higashi, C.-P.J.
Heisenberg, H. Chiba, A.L. Miller, Journal of Cell Science 136 (2023).
date_created: 2023-08-20T22:01:13Z
date_published: 2023-08-01T00:00:00Z
date_updated: 2023-12-13T12:11:18Z
day: '01'
ddc:
- '570'
department:
- _id: CaHe
- _id: EvBe
doi: 10.1242/jcs.260668
ec_funded: 1
external_id:
isi:
- '001070149000001'
file:
- access_level: closed
checksum: a399389b7e3d072f1788b63e612a10b3
content_type: application/pdf
creator: dernst
date_created: 2023-08-21T07:37:54Z
date_updated: 2023-08-21T07:37:54Z
embargo: 2024-08-10
embargo_to: open_access
file_id: '14092'
file_name: 2023_JourCellScience_Higashi.pdf
file_size: 18665315
relation: main_file
file_date_updated: 2023-08-21T07:37:54Z
has_accepted_license: '1'
intvolume: ' 136'
isi: 1
issue: '15'
language:
- iso: eng
month: '08'
oa_version: None
project:
- _id: 260F1432-B435-11E9-9278-68D0E5697425
call_identifier: H2020
grant_number: '742573'
name: Interaction and feedback between cell mechanics and fate specification in
vertebrate gastrulation
publication: Journal of Cell Science
publication_identifier:
eissn:
- 1477-9137
issn:
- 0021-9533
publication_status: published
publisher: The Company of Biologists
quality_controlled: '1'
scopus_import: '1'
status: public
title: ZnUMBA - a live imaging method to detect local barrier breaches
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 136
year: '2023'
...
---
_id: '14827'
abstract:
- lang: eng
text: Understanding complex living systems, which are fundamentally constrained
by physical phenomena, requires combining experimental data with theoretical physical
and mathematical models. To develop such models, collaborations between experimental
cell biologists and theoreticians are increasingly important but these two groups
often face challenges achieving mutual understanding. To help navigate these challenges,
this Perspective discusses different modelling approaches, including bottom-up
hypothesis-driven and top-down data-driven models, and highlights their strengths
and applications. Using cell mechanics as an example, we explore the integration
of specific physical models with experimental data from the molecular, cellular
and tissue level up to multiscale input. We also emphasize the importance of constraining
model complexity and outline strategies for crosstalk between experimental design
and model development. Furthermore, we highlight how physical models can provide
conceptual insights and produce unifying and generalizable frameworks for biological
phenomena. Overall, this Perspective aims to promote fruitful collaborations that
advance our understanding of complex biological systems.
acknowledgement: "We thank Prisca Liberali and Edouard Hannezo for many inspiring
discussions; Mehmet Can Uçar, Nicoletta I Petridou and Qiutan Yang for a critical
reading of the manuscript, and Claudia Flandoli for the artwork in Figs 2 and 3.
We would also like to thank The Company of Biologists for the opportunity to attend
the 2023 workshop on Collective Cell Migration, and all workshop participants for
discussions.\r\nC.S. was supported by a European Molecular Biology Organization
(EMBO) Postdoctoral Fellowship (ALTF 660-2020) and Human Frontier Science Program
(HFSP) Postdoctoral fellowship (LT000746/2021-L). D.B.B. was supported by the NOMIS
Foundation as a NOMIS Fellow and by an EMBO Postdoctoral Fellowship (ALTF 343-2022)."
article_number: jcs.261515
article_processing_charge: No
article_type: original
author:
- first_name: Cornelia
full_name: Schwayer, Cornelia
id: 3436488C-F248-11E8-B48F-1D18A9856A87
last_name: Schwayer
orcid: 0000-0001-5130-2226
- first_name: David
full_name: Brückner, David
id: e1e86031-6537-11eb-953a-f7ab92be508d
last_name: Brückner
orcid: 0000-0001-7205-2975
citation:
ama: Schwayer C, Brückner D. Connecting theory and experiment in cell and tissue
mechanics. Journal of Cell Science. 2023;136(24). doi:10.1242/jcs.261515
apa: Schwayer, C., & Brückner, D. (2023). Connecting theory and experiment in
cell and tissue mechanics. Journal of Cell Science. The Company of Biologists.
https://doi.org/10.1242/jcs.261515
chicago: Schwayer, Cornelia, and David Brückner. “Connecting Theory and Experiment
in Cell and Tissue Mechanics.” Journal of Cell Science. The Company of
Biologists, 2023. https://doi.org/10.1242/jcs.261515.
ieee: C. Schwayer and D. Brückner, “Connecting theory and experiment in cell and
tissue mechanics,” Journal of Cell Science, vol. 136, no. 24. The Company
of Biologists, 2023.
ista: Schwayer C, Brückner D. 2023. Connecting theory and experiment in cell and
tissue mechanics. Journal of Cell Science. 136(24), jcs. 261515.
mla: Schwayer, Cornelia, and David Brückner. “Connecting Theory and Experiment in
Cell and Tissue Mechanics.” Journal of Cell Science, vol. 136, no. 24,
jcs. 261515, The Company of Biologists, 2023, doi:10.1242/jcs.261515.
short: C. Schwayer, D. Brückner, Journal of Cell Science 136 (2023).
date_created: 2024-01-17T12:46:55Z
date_published: 2023-12-27T00:00:00Z
date_updated: 2024-01-22T13:35:48Z
day: '27'
department:
- _id: EdHa
- _id: CaHe
doi: 10.1242/jcs.261515
external_id:
pmid:
- '38149871'
intvolume: ' 136'
issue: '24'
keyword:
- Cell Biology
language:
- iso: eng
month: '12'
oa_version: None
pmid: 1
project:
- _id: 34e2a5b5-11ca-11ed-8bc3-b2265616ef0b
grant_number: 343-2022
name: A mechano-chemical theory for stem cell fate decisions in organoid development
publication: Journal of Cell Science
publication_identifier:
eissn:
- 1477-9137
issn:
- 0021-9533
publication_status: published
publisher: The Company of Biologists
quality_controlled: '1'
scopus_import: '1'
status: public
title: Connecting theory and experiment in cell and tissue mechanics
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 136
year: '2023'
...
---
_id: '14080'
abstract:
- lang: eng
text: Extracellular signal-regulated kinase (ERK) has been recognized as a critical
regulator in various physiological and pathological processes. Extensive research
has elucidated the signaling mechanisms governing ERK activation via biochemical
regulations with upstream molecules, particularly receptor tyrosine kinases (RTKs).
However, recent advances have highlighted the role of mechanical forces in activating
the RTK–ERK signaling pathways, thereby opening new avenues of research into mechanochemical
interplay in multicellular tissues. Here, we review the force-induced ERK activation
in cells and propose possible mechanosensing mechanisms underlying the mechanoresponsive
ERK activation. We conclude that mechanical forces are not merely passive factors
shaping cells and tissues but also active regulators of cellular signaling pathways
controlling collective cell behaviors.
acknowledgement: TH was supported by JSPS KAKENHI Grant (no. 21H05290) and the Ministry
of Education under the Research Centres of Excellence programme through the Mechanobiology
Institute at National University of Singapore and by Department of Physiology at
National University of Singapore. NH was supported by JSPS KAKENHI Grant (no. 20K22653).
KA was supported by JSPS KAKENHI Grants (no. 19H05798 and no. 22H02625). MM was
supported by JSPS KAKENHI Grants (no. 19H00993 and no. 20H05898) and JST Moonshot
R&D Grant JPMJPS2022. We appreciate Virgile Viasnoff and the lab members for their
valuable comments on the manuscript. We apologize to authors whose work could not
be highlighted due to space limitations.
article_number: '102217'
article_processing_charge: Yes (in subscription journal)
article_type: review
author:
- first_name: Tsuyoshi
full_name: Hirashima, Tsuyoshi
last_name: Hirashima
- first_name: Naoya
full_name: Hino, Naoya
id: 5299a9ce-7679-11eb-a7bc-d1e62b936307
last_name: Hino
- first_name: Kazuhiro
full_name: Aoki, Kazuhiro
last_name: Aoki
- first_name: Michiyuki
full_name: Matsuda, Michiyuki
last_name: Matsuda
citation:
ama: Hirashima T, Hino N, Aoki K, Matsuda M. Stretching the limits of extracellular
signal-related kinase (ERK) signaling — Cell mechanosensing to ERK activation.
Current Opinion in Cell Biology. 2023;84(10). doi:10.1016/j.ceb.2023.102217
apa: Hirashima, T., Hino, N., Aoki, K., & Matsuda, M. (2023). Stretching the
limits of extracellular signal-related kinase (ERK) signaling — Cell mechanosensing
to ERK activation. Current Opinion in Cell Biology. Elsevier. https://doi.org/10.1016/j.ceb.2023.102217
chicago: Hirashima, Tsuyoshi, Naoya Hino, Kazuhiro Aoki, and Michiyuki Matsuda.
“Stretching the Limits of Extracellular Signal-Related Kinase (ERK) Signaling
— Cell Mechanosensing to ERK Activation.” Current Opinion in Cell Biology.
Elsevier, 2023. https://doi.org/10.1016/j.ceb.2023.102217.
ieee: T. Hirashima, N. Hino, K. Aoki, and M. Matsuda, “Stretching the limits of
extracellular signal-related kinase (ERK) signaling — Cell mechanosensing to ERK
activation,” Current Opinion in Cell Biology, vol. 84, no. 10. Elsevier,
2023.
ista: Hirashima T, Hino N, Aoki K, Matsuda M. 2023. Stretching the limits of extracellular
signal-related kinase (ERK) signaling — Cell mechanosensing to ERK activation.
Current Opinion in Cell Biology. 84(10), 102217.
mla: Hirashima, Tsuyoshi, et al. “Stretching the Limits of Extracellular Signal-Related
Kinase (ERK) Signaling — Cell Mechanosensing to ERK Activation.” Current Opinion
in Cell Biology, vol. 84, no. 10, 102217, Elsevier, 2023, doi:10.1016/j.ceb.2023.102217.
short: T. Hirashima, N. Hino, K. Aoki, M. Matsuda, Current Opinion in Cell Biology
84 (2023).
date_created: 2023-08-20T22:01:12Z
date_published: 2023-10-01T00:00:00Z
date_updated: 2024-01-30T12:52:42Z
day: '01'
ddc:
- '570'
department:
- _id: CaHe
doi: 10.1016/j.ceb.2023.102217
external_id:
isi:
- '001054692200001'
pmid:
- '37574635'
file:
- access_level: open_access
checksum: 25923f8ae71344e8974530dd23c71bdc
content_type: application/pdf
creator: dernst
date_created: 2024-01-30T12:52:12Z
date_updated: 2024-01-30T12:52:12Z
file_id: '14909'
file_name: 2023_CurrentOpinionCellBio_Hirashima.pdf
file_size: 1173762
relation: main_file
success: 1
file_date_updated: 2024-01-30T12:52:12Z
has_accepted_license: '1'
intvolume: ' 84'
isi: 1
issue: '10'
language:
- iso: eng
month: '10'
oa: 1
oa_version: Published Version
pmid: 1
publication: Current Opinion in Cell Biology
publication_identifier:
eissn:
- 1879-0410
issn:
- 0955-0674
publication_status: published
publisher: Elsevier
quality_controlled: '1'
scopus_import: '1'
status: public
title: Stretching the limits of extracellular signal-related kinase (ERK) signaling
— Cell mechanosensing to ERK activation
tmp:
image: /images/cc_by.png
legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
short: CC BY (4.0)
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 84
year: '2023'
...
---
_id: '9794'
abstract:
- lang: eng
text: 'Lymph nodes (LNs) comprise two main structural elements: fibroblastic reticular
cells that form dedicated niches for immune cell interaction and capsular fibroblasts
that build a shell around the organ. Immunological challenge causes LNs to increase
more than tenfold in size within a few days. Here, we characterized the biomechanics
of LN swelling on the cellular and organ scale. We identified lymphocyte trapping
by influx and proliferation as drivers of an outward pressure force, causing fibroblastic
reticular cells of the T-zone (TRCs) and their associated conduits to stretch.
After an initial phase of relaxation, TRCs sensed the resulting strain through
cell matrix adhesions, which coordinated local growth and remodeling of the stromal
network. While the expanded TRC network readopted its typical configuration, a
massive fibrotic reaction of the organ capsule set in and countered further organ
expansion. Thus, different fibroblast populations mechanically control LN swelling
in a multitier fashion.'
acknowledged_ssus:
- _id: Bio
- _id: EM-Fac
- _id: PreCl
- _id: LifeSc
acknowledgement: This research was supported by the Scientific Service Units of IST
Austria through resources provided by the Imaging and Optics, Electron Microscopy,
Preclinical and Life Science Facilities. We thank C. Moussion for providing anti-PNAd
antibody and D. Critchley for Talin1-floxed mice, and E. Papusheva for providing
a custom 3D channel alignment script. This work was supported by a European Research
Council grant ERC-CoG-72437 to M.S. M.H. was supported by Czech Sciencundation GACR
20-24603Y and Charles University PRIMUS/20/MED/013.
article_processing_charge: No
article_type: original
author:
- first_name: Frank P
full_name: Assen, Frank P
id: 3A8E7F24-F248-11E8-B48F-1D18A9856A87
last_name: Assen
orcid: 0000-0003-3470-6119
- first_name: Jun
full_name: Abe, Jun
last_name: Abe
- first_name: Miroslav
full_name: Hons, Miroslav
id: 4167FE56-F248-11E8-B48F-1D18A9856A87
last_name: Hons
orcid: 0000-0002-6625-3348
- first_name: Robert
full_name: Hauschild, Robert
id: 4E01D6B4-F248-11E8-B48F-1D18A9856A87
last_name: Hauschild
orcid: 0000-0001-9843-3522
- first_name: Shayan
full_name: Shamipour, Shayan
id: 40B34FE2-F248-11E8-B48F-1D18A9856A87
last_name: Shamipour
- first_name: Walter
full_name: Kaufmann, Walter
id: 3F99E422-F248-11E8-B48F-1D18A9856A87
last_name: Kaufmann
orcid: 0000-0001-9735-5315
- first_name: Tommaso
full_name: Costanzo, Tommaso
id: D93824F4-D9BA-11E9-BB12-F207E6697425
last_name: Costanzo
orcid: 0000-0001-9732-3815
- first_name: Gabriel
full_name: Krens, Gabriel
id: 2B819732-F248-11E8-B48F-1D18A9856A87
last_name: Krens
orcid: 0000-0003-4761-5996
- first_name: Markus
full_name: Brown, Markus
id: 3DAB9AFC-F248-11E8-B48F-1D18A9856A87
last_name: Brown
- first_name: Burkhard
full_name: Ludewig, Burkhard
last_name: Ludewig
- first_name: Simon
full_name: Hippenmeyer, Simon
id: 37B36620-F248-11E8-B48F-1D18A9856A87
last_name: Hippenmeyer
orcid: 0000-0003-2279-1061
- first_name: Carl-Philipp J
full_name: Heisenberg, Carl-Philipp J
id: 39427864-F248-11E8-B48F-1D18A9856A87
last_name: Heisenberg
orcid: 0000-0002-0912-4566
- first_name: Wolfgang
full_name: Weninger, Wolfgang
last_name: Weninger
- first_name: Edouard B
full_name: Hannezo, Edouard B
id: 3A9DB764-F248-11E8-B48F-1D18A9856A87
last_name: Hannezo
orcid: 0000-0001-6005-1561
- first_name: Sanjiv A.
full_name: Luther, Sanjiv A.
last_name: Luther
- first_name: Jens V.
full_name: Stein, Jens V.
last_name: Stein
- first_name: Michael K
full_name: Sixt, Michael K
id: 41E9FBEA-F248-11E8-B48F-1D18A9856A87
last_name: Sixt
orcid: 0000-0002-4561-241X
citation:
ama: Assen FP, Abe J, Hons M, et al. Multitier mechanics control stromal adaptations
in swelling lymph nodes. Nature Immunology. 2022;23:1246-1255. doi:10.1038/s41590-022-01257-4
apa: Assen, F. P., Abe, J., Hons, M., Hauschild, R., Shamipour, S., Kaufmann, W.,
… Sixt, M. K. (2022). Multitier mechanics control stromal adaptations in swelling
lymph nodes. Nature Immunology. Springer Nature. https://doi.org/10.1038/s41590-022-01257-4
chicago: Assen, Frank P, Jun Abe, Miroslav Hons, Robert Hauschild, Shayan Shamipour,
Walter Kaufmann, Tommaso Costanzo, et al. “Multitier Mechanics Control Stromal
Adaptations in Swelling Lymph Nodes.” Nature Immunology. Springer Nature,
2022. https://doi.org/10.1038/s41590-022-01257-4.
ieee: F. P. Assen et al., “Multitier mechanics control stromal adaptations
in swelling lymph nodes,” Nature Immunology, vol. 23. Springer Nature,
pp. 1246–1255, 2022.
ista: Assen FP, Abe J, Hons M, Hauschild R, Shamipour S, Kaufmann W, Costanzo T,
Krens G, Brown M, Ludewig B, Hippenmeyer S, Heisenberg C-PJ, Weninger W, Hannezo
EB, Luther SA, Stein JV, Sixt MK. 2022. Multitier mechanics control stromal adaptations
in swelling lymph nodes. Nature Immunology. 23, 1246–1255.
mla: Assen, Frank P., et al. “Multitier Mechanics Control Stromal Adaptations in
Swelling Lymph Nodes.” Nature Immunology, vol. 23, Springer Nature, 2022,
pp. 1246–55, doi:10.1038/s41590-022-01257-4.
short: F.P. Assen, J. Abe, M. Hons, R. Hauschild, S. Shamipour, W. Kaufmann, T.
Costanzo, G. Krens, M. Brown, B. Ludewig, S. Hippenmeyer, C.-P.J. Heisenberg,
W. Weninger, E.B. Hannezo, S.A. Luther, J.V. Stein, M.K. Sixt, Nature Immunology
23 (2022) 1246–1255.
date_created: 2021-08-06T09:09:11Z
date_published: 2022-07-11T00:00:00Z
date_updated: 2023-08-02T06:53:07Z
day: '11'
ddc:
- '570'
department:
- _id: SiHi
- _id: CaHe
- _id: EdHa
- _id: EM-Fac
- _id: Bio
- _id: MiSi
doi: 10.1038/s41590-022-01257-4
ec_funded: 1
external_id:
isi:
- '000822975900002'
file:
- access_level: open_access
checksum: 628e7b49809f22c75b428842efe70c68
content_type: application/pdf
creator: dernst
date_created: 2022-07-25T07:11:32Z
date_updated: 2022-07-25T07:11:32Z
file_id: '11642'
file_name: 2022_NatureImmunology_Assen.pdf
file_size: 11475325
relation: main_file
success: 1
file_date_updated: 2022-07-25T07:11:32Z
has_accepted_license: '1'
intvolume: ' 23'
isi: 1
language:
- iso: eng
month: '07'
oa: 1
oa_version: Published Version
page: 1246-1255
project:
- _id: 25FE9508-B435-11E9-9278-68D0E5697425
call_identifier: H2020
grant_number: '724373'
name: Cellular navigation along spatial gradients
publication: Nature Immunology
publication_identifier:
eissn:
- 1529-2916
issn:
- 1529-2908
publication_status: published
publisher: Springer Nature
quality_controlled: '1'
scopus_import: '1'
status: public
title: Multitier mechanics control stromal adaptations in swelling lymph nodes
tmp:
image: /images/cc_by.png
legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
short: CC BY (4.0)
type: journal_article
user_id: 4359f0d1-fa6c-11eb-b949-802e58b17ae8
volume: 23
year: '2022'
...
---
_id: '10705'
abstract:
- lang: eng
text: Although rigidity and jamming transitions have been widely studied in physics
and material science, their importance in a number of biological processes, including
embryo development, tissue homeostasis, wound healing, and disease progression,
has only begun to be recognized in the past few years. The hypothesis that biological
systems can undergo rigidity/jamming transitions is attractive, as it would allow
these systems to change their material properties rapidly and strongly. However,
whether such transitions indeed occur in biological systems, how they are being
regulated, and what their physiological relevance might be, is still being debated.
Here, we review theoretical and experimental advances from the past few years,
focusing on the regulation and role of potential tissue rigidity transitions in
different biological processes.
acknowledgement: We thank present and former members of the Heisenberg and Hannezo
groups, in particular Bernat Corominas-Murtra and Nicoletta Petridou, for helpful
discussions, and Claudia Flandoli for the artwork. We apologize for not being able
to cite a number of highly relevant studies, to stay within the maximum allowed
number of citations.
article_processing_charge: No
article_type: original
author:
- first_name: Edouard B
full_name: Hannezo, Edouard B
id: 3A9DB764-F248-11E8-B48F-1D18A9856A87
last_name: Hannezo
orcid: 0000-0001-6005-1561
- first_name: Carl-Philipp J
full_name: Heisenberg, Carl-Philipp J
id: 39427864-F248-11E8-B48F-1D18A9856A87
last_name: Heisenberg
orcid: 0000-0002-0912-4566
citation:
ama: Hannezo EB, Heisenberg C-PJ. Rigidity transitions in development and disease.
Trends in Cell Biology. 2022;32(5):P433-444. doi:10.1016/j.tcb.2021.12.006
apa: Hannezo, E. B., & Heisenberg, C.-P. J. (2022). Rigidity transitions in
development and disease. Trends in Cell Biology. Cell Press. https://doi.org/10.1016/j.tcb.2021.12.006
chicago: Hannezo, Edouard B, and Carl-Philipp J Heisenberg. “Rigidity Transitions
in Development and Disease.” Trends in Cell Biology. Cell Press, 2022.
https://doi.org/10.1016/j.tcb.2021.12.006.
ieee: E. B. Hannezo and C.-P. J. Heisenberg, “Rigidity transitions in development
and disease,” Trends in Cell Biology, vol. 32, no. 5. Cell Press, pp. P433-444,
2022.
ista: Hannezo EB, Heisenberg C-PJ. 2022. Rigidity transitions in development and
disease. Trends in Cell Biology. 32(5), P433-444.
mla: Hannezo, Edouard B., and Carl-Philipp J. Heisenberg. “Rigidity Transitions
in Development and Disease.” Trends in Cell Biology, vol. 32, no. 5, Cell
Press, 2022, pp. P433-444, doi:10.1016/j.tcb.2021.12.006.
short: E.B. Hannezo, C.-P.J. Heisenberg, Trends in Cell Biology 32 (2022) P433-444.
date_created: 2022-01-30T23:01:34Z
date_published: 2022-05-01T00:00:00Z
date_updated: 2023-08-02T14:03:53Z
day: '01'
department:
- _id: EdHa
- _id: CaHe
doi: 10.1016/j.tcb.2021.12.006
external_id:
isi:
- '000795773900009'
pmid:
- '35058104'
intvolume: ' 32'
isi: 1
issue: '5'
language:
- iso: eng
month: '05'
oa_version: None
page: P433-444
pmid: 1
publication: Trends in Cell Biology
publication_identifier:
eissn:
- 1879-3088
issn:
- 0962-8924
publication_status: published
publisher: Cell Press
quality_controlled: '1'
scopus_import: '1'
status: public
title: Rigidity transitions in development and disease
type: journal_article
user_id: 4359f0d1-fa6c-11eb-b949-802e58b17ae8
volume: 32
year: '2022'
...
---
_id: '10766'
abstract:
- lang: eng
text: Tension of the actomyosin cell cortex plays a key role in determining cell–cell
contact growth and size. The level of cortical tension outside of the cell–cell
contact, when pulling at the contact edge, scales with the total size to which
a cell–cell contact can grow [J.-L. Maître et al., Science 338, 253–256 (2012)].
Here, we show in zebrafish primary germ-layer progenitor cells that this monotonic
relationship only applies to a narrow range of cortical tension increase and that
above a critical threshold, contact size inversely scales with cortical tension.
This switch from cortical tension increasing to decreasing progenitor cell–cell
contact size is caused by cortical tension promoting E-cadherin anchoring to the
actomyosin cytoskeleton, thereby increasing clustering and stability of E-cadherin
at the contact. After tension-mediated E-cadherin stabilization at the contact
exceeds a critical threshold level, the rate by which the contact expands in response
to pulling forces from the cortex sharply drops, leading to smaller contacts at
physiologically relevant timescales of contact formation. Thus, the activity of
cortical tension in expanding cell–cell contact size is limited by tension-stabilizing
E-cadherin–actin complexes at the contact.
acknowledged_ssus:
- _id: Bio
- _id: EM-Fac
- _id: PreCl
acknowledgement: 'We thank Guillaume Salbreaux, Silvia Grigolon, Edouard Hannezo,
and Vanessa Barone for discussions and comments on the manuscript and Shayan Shamipour
and Daniel Capek for help with data analysis. We also thank the Imaging & Optics,
Electron Microscopy, and Zebrafish Facility Scientific Service Units at the Institute
of Science and Technology Austria (ISTA)Nasser Darwish-Miranda for continuous support.
We acknowledge Hitoshi Morita for the gift of VinculinB-GFP plasmid. This research
was supported by an ISTA Fellow Marie-Curie Co-funding of regional, national, and
international programmes Grant P_IST_EU01 (to J.S.), European Molecular Biology
Organization Long-Term Fellowship Grant, ALTF reference number: 187-2013 (to M.S.),
Schroedinger Fellowship J4332-B28 (to M.S.), and European Research Council Advanced
Grant (MECSPEC; to C.-P.H.).'
article_number: e2122030119
article_processing_charge: No
article_type: original
author:
- first_name: Jana
full_name: Slovakova, Jana
id: 30F3F2F0-F248-11E8-B48F-1D18A9856A87
last_name: Slovakova
- first_name: Mateusz K
full_name: Sikora, Mateusz K
id: 2F74BCDE-F248-11E8-B48F-1D18A9856A87
last_name: Sikora
- first_name: Feyza N
full_name: Arslan, Feyza N
id: 49DA7910-F248-11E8-B48F-1D18A9856A87
last_name: Arslan
orcid: 0000-0001-5809-9566
- first_name: Silvia
full_name: Caballero Mancebo, Silvia
id: 2F1E1758-F248-11E8-B48F-1D18A9856A87
last_name: Caballero Mancebo
orcid: 0000-0002-5223-3346
- first_name: Gabriel
full_name: Krens, Gabriel
id: 2B819732-F248-11E8-B48F-1D18A9856A87
last_name: Krens
orcid: 0000-0003-4761-5996
- first_name: Walter
full_name: Kaufmann, Walter
id: 3F99E422-F248-11E8-B48F-1D18A9856A87
last_name: Kaufmann
orcid: 0000-0001-9735-5315
- first_name: Jack
full_name: Merrin, Jack
id: 4515C308-F248-11E8-B48F-1D18A9856A87
last_name: Merrin
orcid: 0000-0001-5145-4609
- first_name: Carl-Philipp J
full_name: Heisenberg, Carl-Philipp J
id: 39427864-F248-11E8-B48F-1D18A9856A87
last_name: Heisenberg
orcid: 0000-0002-0912-4566
citation:
ama: Slovakova J, Sikora MK, Arslan FN, et al. Tension-dependent stabilization of
E-cadherin limits cell-cell contact expansion in zebrafish germ-layer progenitor
cells. Proceedings of the National Academy of Sciences of the United States
of America. 2022;119(8). doi:10.1073/pnas.2122030119
apa: Slovakova, J., Sikora, M. K., Arslan, F. N., Caballero Mancebo, S., Krens,
G., Kaufmann, W., … Heisenberg, C.-P. J. (2022). Tension-dependent stabilization
of E-cadherin limits cell-cell contact expansion in zebrafish germ-layer progenitor
cells. Proceedings of the National Academy of Sciences of the United States
of America. Proceedings of the National Academy of Sciences. https://doi.org/10.1073/pnas.2122030119
chicago: Slovakova, Jana, Mateusz K Sikora, Feyza N Arslan, Silvia Caballero Mancebo,
Gabriel Krens, Walter Kaufmann, Jack Merrin, and Carl-Philipp J Heisenberg. “Tension-Dependent
Stabilization of E-Cadherin Limits Cell-Cell Contact Expansion in Zebrafish Germ-Layer
Progenitor Cells.” Proceedings of the National Academy of Sciences of the United
States of America. Proceedings of the National Academy of Sciences, 2022.
https://doi.org/10.1073/pnas.2122030119.
ieee: J. Slovakova et al., “Tension-dependent stabilization of E-cadherin
limits cell-cell contact expansion in zebrafish germ-layer progenitor cells,”
Proceedings of the National Academy of Sciences of the United States of America,
vol. 119, no. 8. Proceedings of the National Academy of Sciences, 2022.
ista: Slovakova J, Sikora MK, Arslan FN, Caballero Mancebo S, Krens G, Kaufmann
W, Merrin J, Heisenberg C-PJ. 2022. Tension-dependent stabilization of E-cadherin
limits cell-cell contact expansion in zebrafish germ-layer progenitor cells. Proceedings
of the National Academy of Sciences of the United States of America. 119(8), e2122030119.
mla: Slovakova, Jana, et al. “Tension-Dependent Stabilization of E-Cadherin Limits
Cell-Cell Contact Expansion in Zebrafish Germ-Layer Progenitor Cells.” Proceedings
of the National Academy of Sciences of the United States of America, vol.
119, no. 8, e2122030119, Proceedings of the National Academy of Sciences, 2022,
doi:10.1073/pnas.2122030119.
short: J. Slovakova, M.K. Sikora, F.N. Arslan, S. Caballero Mancebo, G. Krens, W.
Kaufmann, J. Merrin, C.-P.J. Heisenberg, Proceedings of the National Academy of
Sciences of the United States of America 119 (2022).
date_created: 2022-02-20T23:01:31Z
date_published: 2022-02-14T00:00:00Z
date_updated: 2023-08-02T14:26:51Z
day: '14'
ddc:
- '570'
department:
- _id: CaHe
- _id: EM-Fac
- _id: Bio
doi: 10.1073/pnas.2122030119
ec_funded: 1
external_id:
isi:
- '000766926900009'
file:
- access_level: open_access
checksum: d49f83c3580613966f71768ddb9a55a5
content_type: application/pdf
creator: dernst
date_created: 2022-02-21T08:45:11Z
date_updated: 2022-02-21T08:45:11Z
file_id: '10780'
file_name: 2022_PNAS_Slovakova.pdf
file_size: 1609678
relation: main_file
success: 1
file_date_updated: 2022-02-21T08:45:11Z
has_accepted_license: '1'
intvolume: ' 119'
isi: 1
issue: '8'
language:
- iso: eng
license: https://creativecommons.org/licenses/by-nc-nd/4.0/
month: '02'
oa: 1
oa_version: Published Version
project:
- _id: 25681D80-B435-11E9-9278-68D0E5697425
call_identifier: FP7
grant_number: '291734'
name: International IST Postdoc Fellowship Programme
- _id: 260F1432-B435-11E9-9278-68D0E5697425
call_identifier: H2020
grant_number: '742573'
name: Interaction and feedback between cell mechanics and fate specification in
vertebrate gastrulation
- _id: 2521E28E-B435-11E9-9278-68D0E5697425
grant_number: 187-2013
name: Modulation of adhesion function in cell-cell contact formation by cortical
tension
publication: Proceedings of the National Academy of Sciences of the United States
of America
publication_identifier:
eissn:
- '10916490'
publication_status: published
publisher: Proceedings of the National Academy of Sciences
quality_controlled: '1'
related_material:
record:
- id: '9750'
relation: earlier_version
status: public
scopus_import: '1'
status: public
title: Tension-dependent stabilization of E-cadherin limits cell-cell contact expansion
in zebrafish germ-layer progenitor cells
tmp:
image: /images/cc_by_nc_nd.png
legal_code_url: https://creativecommons.org/licenses/by-nc-nd/4.0/legalcode
name: Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International
(CC BY-NC-ND 4.0)
short: CC BY-NC-ND (4.0)
type: journal_article
user_id: 4359f0d1-fa6c-11eb-b949-802e58b17ae8
volume: 119
year: '2022'
...
---
_id: '12209'
abstract:
- lang: eng
text: Embryo development requires biochemical signalling to generate patterns of
cell fates and active mechanical forces to drive tissue shape changes. However,
how these processes are coordinated, and how tissue patterning is preserved despite
the cellular flows occurring during morphogenesis, remains poorly understood.
Gastrulation is a crucial embryonic stage that involves both patterning and internalization
of the mesendoderm germ layer tissue. Here we show that, in zebrafish embryos,
a gradient in Nodal signalling orchestrates pattern-preserving internalization
movements by triggering a motility-driven unjamming transition. In addition to
its role as a morphogen determining embryo patterning, graded Nodal signalling
mechanically subdivides the mesendoderm into a small fraction of highly protrusive
leader cells, able to autonomously internalize via local unjamming, and less protrusive
followers, which need to be pulled inwards by the leaders. The Nodal gradient
further enforces a code of preferential adhesion coupling leaders to their immediate
followers, resulting in a collective and ordered mode of internalization that
preserves mesendoderm patterning. Integrating this dual mechanical role of Nodal
signalling into minimal active particle simulations quantitatively predicts both
physiological and experimentally perturbed internalization movements. This provides
a quantitative framework for how a morphogen-encoded unjamming transition can
bidirectionally couple tissue mechanics with patterning during complex three-dimensional
morphogenesis.
acknowledged_ssus:
- _id: Bio
- _id: LifeSc
acknowledgement: "We thank K. Sampath, A. Pauli and Y. Bellaїche for feedback on the
manuscript. We also thank the members of the Heisenberg group, in particular A.
Schauer and F. Nur Arslan, for help, technical advice and discussions, and the Bioimaging
and Life Science facilities at IST\r\nAustria for continuous support. We thank C.
Flandoli for the artwork in the figures. This work was supported by postdoctoral
fellowships from EMBO (LTF-850-2017) and HFSP (LT000429/2018-L2) to D.P. and the
European Union (European Research Council starting grant 851288 to É.H. and European
Research Council advanced grant 742573 to C.-P.H.)."
article_processing_charge: No
article_type: original
author:
- first_name: Diana C
full_name: Nunes Pinheiro, Diana C
id: 2E839F16-F248-11E8-B48F-1D18A9856A87
last_name: Nunes Pinheiro
orcid: 0000-0003-4333-7503
- first_name: Roland
full_name: Kardos, Roland
id: 4039350E-F248-11E8-B48F-1D18A9856A87
last_name: Kardos
- first_name: Edouard B
full_name: Hannezo, Edouard B
id: 3A9DB764-F248-11E8-B48F-1D18A9856A87
last_name: Hannezo
orcid: 0000-0001-6005-1561
- first_name: Carl-Philipp J
full_name: Heisenberg, Carl-Philipp J
id: 39427864-F248-11E8-B48F-1D18A9856A87
last_name: Heisenberg
orcid: 0000-0002-0912-4566
citation:
ama: Nunes Pinheiro DC, Kardos R, Hannezo EB, Heisenberg C-PJ. Morphogen gradient
orchestrates pattern-preserving tissue morphogenesis via motility-driven unjamming.
Nature Physics. 2022;18(12):1482-1493. doi:10.1038/s41567-022-01787-6
apa: Nunes Pinheiro, D. C., Kardos, R., Hannezo, E. B., & Heisenberg, C.-P.
J. (2022). Morphogen gradient orchestrates pattern-preserving tissue morphogenesis
via motility-driven unjamming. Nature Physics. Springer Nature. https://doi.org/10.1038/s41567-022-01787-6
chicago: Nunes Pinheiro, Diana C, Roland Kardos, Edouard B Hannezo, and Carl-Philipp
J Heisenberg. “Morphogen Gradient Orchestrates Pattern-Preserving Tissue Morphogenesis
via Motility-Driven Unjamming.” Nature Physics. Springer Nature, 2022.
https://doi.org/10.1038/s41567-022-01787-6.
ieee: D. C. Nunes Pinheiro, R. Kardos, E. B. Hannezo, and C.-P. J. Heisenberg, “Morphogen
gradient orchestrates pattern-preserving tissue morphogenesis via motility-driven
unjamming,” Nature Physics, vol. 18, no. 12. Springer Nature, pp. 1482–1493,
2022.
ista: Nunes Pinheiro DC, Kardos R, Hannezo EB, Heisenberg C-PJ. 2022. Morphogen
gradient orchestrates pattern-preserving tissue morphogenesis via motility-driven
unjamming. Nature Physics. 18(12), 1482–1493.
mla: Nunes Pinheiro, Diana C., et al. “Morphogen Gradient Orchestrates Pattern-Preserving
Tissue Morphogenesis via Motility-Driven Unjamming.” Nature Physics, vol.
18, no. 12, Springer Nature, 2022, pp. 1482–93, doi:10.1038/s41567-022-01787-6.
short: D.C. Nunes Pinheiro, R. Kardos, E.B. Hannezo, C.-P.J. Heisenberg, Nature
Physics 18 (2022) 1482–1493.
date_created: 2023-01-16T09:45:19Z
date_published: 2022-12-01T00:00:00Z
date_updated: 2023-08-04T09:15:58Z
day: '01'
ddc:
- '570'
department:
- _id: CaHe
- _id: EdHa
doi: 10.1038/s41567-022-01787-6
ec_funded: 1
external_id:
isi:
- '000871319900002'
file:
- access_level: open_access
checksum: c86a8e8d80d1bfc46d56a01e88a2526a
content_type: application/pdf
creator: dernst
date_created: 2023-01-27T07:32:01Z
date_updated: 2023-01-27T07:32:01Z
file_id: '12412'
file_name: 2022_NaturePhysics_Pinheiro.pdf
file_size: 36703569
relation: main_file
success: 1
file_date_updated: 2023-01-27T07:32:01Z
has_accepted_license: '1'
intvolume: ' 18'
isi: 1
issue: '12'
keyword:
- General Physics and Astronomy
language:
- iso: eng
month: '12'
oa: 1
oa_version: Published Version
page: 1482-1493
project:
- _id: 26520D1E-B435-11E9-9278-68D0E5697425
grant_number: ALTF 850-2017
name: Coordination of mesendoderm cell fate specification and internalization during
zebrafish gastrulation
- _id: 26520D1E-B435-11E9-9278-68D0E5697425
grant_number: ALTF 850-2017
name: Coordination of mesendoderm cell fate specification and internalization during
zebrafish gastrulation
- _id: 05943252-7A3F-11EA-A408-12923DDC885E
call_identifier: H2020
grant_number: '851288'
name: Design Principles of Branching Morphogenesis
- _id: 260F1432-B435-11E9-9278-68D0E5697425
call_identifier: H2020
grant_number: '742573'
name: Interaction and feedback between cell mechanics and fate specification in
vertebrate gastrulation
publication: Nature Physics
publication_identifier:
eissn:
- 1745-2481
issn:
- 1745-2473
publication_status: published
publisher: Springer Nature
quality_controlled: '1'
scopus_import: '1'
status: public
title: Morphogen gradient orchestrates pattern-preserving tissue morphogenesis via
motility-driven unjamming
tmp:
image: /images/cc_by.png
legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
short: CC BY (4.0)
type: journal_article
user_id: 4359f0d1-fa6c-11eb-b949-802e58b17ae8
volume: 18
year: '2022'
...
---
_id: '12231'
abstract:
- lang: eng
text: Ventral tail bending, which is transient but pronounced, is found in many
chordate embryos and constitutes an interesting model of how tissue interactions
control embryo shape. Here, we identify one key upstream regulator of ventral
tail bending in embryos of the ascidian Ciona. We show that during the early tailbud
stages, ventral epidermal cells exhibit a boat-shaped morphology (boat cell) with
a narrow apical surface where phosphorylated myosin light chain (pMLC) accumulates.
We further show that interfering with the function of the BMP ligand Admp led
to pMLC localizing to the basal instead of the apical side of ventral epidermal
cells and a reduced number of boat cells. Finally, we show that cutting ventral
epidermal midline cells at their apex using an ultraviolet laser relaxed ventral
tail bending. Based on these results, we propose a previously unreported function
for Admp in localizing pMLC to the apical side of ventral epidermal cells, which
causes the tail to bend ventrally by resisting antero-posterior notochord extension
at the ventral side of the tail.
acknowledgement: "iona intestinalis adults were provided by Dr Yutaka Satou (Kyoto
University) and Dr Manabu Yoshida (the University of Tokyo) with support from the
National Bio-Resource Project of AMED, Japan. We thank Dr Hidehiko Hashimoto and
Dr Yuji Mizotani for technical information about 1P-myosin antibody staining. We
thank Dr Kaoru Imai and Dr Yutaka Satou for valuable discussion about Admp and for
the DNA construct of Bmp2/4 under the Dlx.b upstream sequence. We thank Ms Maki
Kogure for constructing the FUSION360 of the intercalating epidermal cell.\r\nThis
work was supported by funding from the Japan Society for the Promotion of Science
(JP16H01451, JP21H00440). Open Access funding provided by Keio University: Keio
Gijuku Daigaku."
article_number: dev200215
article_processing_charge: No
article_type: original
author:
- first_name: Yuki S.
full_name: Kogure, Yuki S.
last_name: Kogure
- first_name: Hiromochi
full_name: Muraoka, Hiromochi
last_name: Muraoka
- first_name: Wataru C.
full_name: Koizumi, Wataru C.
last_name: Koizumi
- first_name: Raphaël
full_name: Gelin-alessi, Raphaël
last_name: Gelin-alessi
- first_name: Benoit G
full_name: Godard, Benoit G
id: 3263621A-F248-11E8-B48F-1D18A9856A87
last_name: Godard
- first_name: Kotaro
full_name: Oka, Kotaro
last_name: Oka
- first_name: Carl-Philipp J
full_name: Heisenberg, Carl-Philipp J
id: 39427864-F248-11E8-B48F-1D18A9856A87
last_name: Heisenberg
orcid: 0000-0002-0912-4566
- first_name: Kohji
full_name: Hotta, Kohji
last_name: Hotta
citation:
ama: Kogure YS, Muraoka H, Koizumi WC, et al. Admp regulates tail bending by controlling
ventral epidermal cell polarity via phosphorylated myosin localization in Ciona.
Development. 2022;149(21). doi:10.1242/dev.200215
apa: Kogure, Y. S., Muraoka, H., Koizumi, W. C., Gelin-alessi, R., Godard, B. G.,
Oka, K., … Hotta, K. (2022). Admp regulates tail bending by controlling ventral
epidermal cell polarity via phosphorylated myosin localization in Ciona. Development.
The Company of Biologists. https://doi.org/10.1242/dev.200215
chicago: Kogure, Yuki S., Hiromochi Muraoka, Wataru C. Koizumi, Raphaël Gelin-alessi,
Benoit G Godard, Kotaro Oka, Carl-Philipp J Heisenberg, and Kohji Hotta. “Admp
Regulates Tail Bending by Controlling Ventral Epidermal Cell Polarity via Phosphorylated
Myosin Localization in Ciona.” Development. The Company of Biologists,
2022. https://doi.org/10.1242/dev.200215.
ieee: Y. S. Kogure et al., “Admp regulates tail bending by controlling ventral
epidermal cell polarity via phosphorylated myosin localization in Ciona,” Development,
vol. 149, no. 21. The Company of Biologists, 2022.
ista: Kogure YS, Muraoka H, Koizumi WC, Gelin-alessi R, Godard BG, Oka K, Heisenberg
C-PJ, Hotta K. 2022. Admp regulates tail bending by controlling ventral epidermal
cell polarity via phosphorylated myosin localization in Ciona. Development. 149(21),
dev200215.
mla: Kogure, Yuki S., et al. “Admp Regulates Tail Bending by Controlling Ventral
Epidermal Cell Polarity via Phosphorylated Myosin Localization in Ciona.” Development,
vol. 149, no. 21, dev200215, The Company of Biologists, 2022, doi:10.1242/dev.200215.
short: Y.S. Kogure, H. Muraoka, W.C. Koizumi, R. Gelin-alessi, B.G. Godard, K. Oka,
C.-P.J. Heisenberg, K. Hotta, Development 149 (2022).
date_created: 2023-01-16T09:50:12Z
date_published: 2022-11-01T00:00:00Z
date_updated: 2023-08-04T09:33:24Z
day: '01'
ddc:
- '570'
department:
- _id: CaHe
doi: 10.1242/dev.200215
external_id:
isi:
- '000903991700002'
pmid:
- '36227591'
file:
- access_level: open_access
checksum: 871b9c58eb79b9e60752de25a46938d6
content_type: application/pdf
creator: dernst
date_created: 2023-01-27T10:36:50Z
date_updated: 2023-01-27T10:36:50Z
file_id: '12423'
file_name: 2022_Development_Kogure.pdf
file_size: 9160451
relation: main_file
success: 1
file_date_updated: 2023-01-27T10:36:50Z
has_accepted_license: '1'
intvolume: ' 149'
isi: 1
issue: '21'
keyword:
- Developmental Biology
- Molecular Biology
language:
- iso: eng
month: '11'
oa: 1
oa_version: Published Version
pmid: 1
publication: Development
publication_identifier:
eissn:
- 1477-9129
issn:
- 0950-1991
publication_status: published
publisher: The Company of Biologists
quality_controlled: '1'
scopus_import: '1'
status: public
title: Admp regulates tail bending by controlling ventral epidermal cell polarity
via phosphorylated myosin localization in Ciona
tmp:
image: /images/cc_by.png
legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
short: CC BY (4.0)
type: journal_article
user_id: 4359f0d1-fa6c-11eb-b949-802e58b17ae8
volume: 149
year: '2022'
...
---
_id: '12238'
abstract:
- lang: eng
text: Upon the initiation of collective cell migration, the cells at the free edge
are specified as leader cells; however, the mechanism underlying the leader cell
specification remains elusive. Here, we show that lamellipodial extension after
the release from mechanical confinement causes sustained extracellular signal-regulated
kinase (ERK) activation and underlies the leader cell specification. Live-imaging
of Madin-Darby canine kidney (MDCK) cells and mouse epidermis through the use
of Förster resonance energy transfer (FRET)-based biosensors showed that leader
cells exhibit sustained ERK activation in a hepatocyte growth factor (HGF)-dependent
manner. Meanwhile, follower cells exhibit oscillatory ERK activation waves in
an epidermal growth factor (EGF) signaling-dependent manner. Lamellipodial extension
at the free edge increases the cellular sensitivity to HGF. The HGF-dependent
ERK activation, in turn, promotes lamellipodial extension, thereby forming a positive
feedback loop between cell extension and ERK activation and specifying the cells
at the free edge as the leader cells. Our findings show that the integration of
physical and biochemical cues underlies the leader cell specification during collective
cell migration.
acknowledgement: We thank the members of the Matsuda Laboratory for their helpful
discussion and encouragement, and we thank K. Hirano and K. Takakura for their technical
assistance. This work was supported by the Kyoto University Live Imaging Center.
Financial support was provided in the form of JSPS KAKENHI grants (nos. 17J02107
and 20K22653 to N.H., and 20H05898 and 19H00993 to M.M.), a JST CREST grant (no.
JPMJCR1654 to M.M.), a Moonshot R&D grant (no. JPMJPS2022-11 to M.M.), Generalitat
de Catalunya and the CERCA Programme (no. SGR-2017-01602 to X.T.), MICCINN/FEDER
(no. PGC2018-099645-B-I00 to X.T.), and European Research Council (no. Adv-883739
to X.T.). IBEC is a recipient of a Severo Ochoa Award of Excellence from the MINECO.
This work was partly supported by an Extramural Collaborative Research Grant of
Cancer Research Institute, Kanazawa University.
article_processing_charge: No
article_type: original
author:
- first_name: Naoya
full_name: Hino, Naoya
id: 5299a9ce-7679-11eb-a7bc-d1e62b936307
last_name: Hino
- first_name: Kimiya
full_name: Matsuda, Kimiya
last_name: Matsuda
- first_name: Yuya
full_name: Jikko, Yuya
last_name: Jikko
- first_name: Gembu
full_name: Maryu, Gembu
last_name: Maryu
- first_name: Katsuya
full_name: Sakai, Katsuya
last_name: Sakai
- first_name: Ryu
full_name: Imamura, Ryu
last_name: Imamura
- first_name: Shinya
full_name: Tsukiji, Shinya
last_name: Tsukiji
- first_name: Kazuhiro
full_name: Aoki, Kazuhiro
last_name: Aoki
- first_name: Kenta
full_name: Terai, Kenta
last_name: Terai
- first_name: Tsuyoshi
full_name: Hirashima, Tsuyoshi
last_name: Hirashima
- first_name: Xavier
full_name: Trepat, Xavier
last_name: Trepat
- first_name: Michiyuki
full_name: Matsuda, Michiyuki
last_name: Matsuda
citation:
ama: Hino N, Matsuda K, Jikko Y, et al. A feedback loop between lamellipodial extension
and HGF-ERK signaling specifies leader cells during collective cell migration.
Developmental Cell. 2022;57(19):2290-2304.e7. doi:10.1016/j.devcel.2022.09.003
apa: Hino, N., Matsuda, K., Jikko, Y., Maryu, G., Sakai, K., Imamura, R., … Matsuda,
M. (2022). A feedback loop between lamellipodial extension and HGF-ERK signaling
specifies leader cells during collective cell migration. Developmental Cell.
Elsevier. https://doi.org/10.1016/j.devcel.2022.09.003
chicago: Hino, Naoya, Kimiya Matsuda, Yuya Jikko, Gembu Maryu, Katsuya Sakai, Ryu
Imamura, Shinya Tsukiji, et al. “A Feedback Loop between Lamellipodial Extension
and HGF-ERK Signaling Specifies Leader Cells during Collective Cell Migration.”
Developmental Cell. Elsevier, 2022. https://doi.org/10.1016/j.devcel.2022.09.003.
ieee: N. Hino et al., “A feedback loop between lamellipodial extension and
HGF-ERK signaling specifies leader cells during collective cell migration,” Developmental
Cell, vol. 57, no. 19. Elsevier, p. 2290–2304.e7, 2022.
ista: Hino N, Matsuda K, Jikko Y, Maryu G, Sakai K, Imamura R, Tsukiji S, Aoki K,
Terai K, Hirashima T, Trepat X, Matsuda M. 2022. A feedback loop between lamellipodial
extension and HGF-ERK signaling specifies leader cells during collective cell
migration. Developmental Cell. 57(19), 2290–2304.e7.
mla: Hino, Naoya, et al. “A Feedback Loop between Lamellipodial Extension and HGF-ERK
Signaling Specifies Leader Cells during Collective Cell Migration.” Developmental
Cell, vol. 57, no. 19, Elsevier, 2022, p. 2290–2304.e7, doi:10.1016/j.devcel.2022.09.003.
short: N. Hino, K. Matsuda, Y. Jikko, G. Maryu, K. Sakai, R. Imamura, S. Tsukiji,
K. Aoki, K. Terai, T. Hirashima, X. Trepat, M. Matsuda, Developmental Cell 57
(2022) 2290–2304.e7.
date_created: 2023-01-16T09:51:39Z
date_published: 2022-10-01T00:00:00Z
date_updated: 2023-08-04T09:38:53Z
day: '01'
department:
- _id: CaHe
doi: 10.1016/j.devcel.2022.09.003
external_id:
isi:
- '000898428700006'
pmid:
- '36174555'
intvolume: ' 57'
isi: 1
issue: '19'
keyword:
- Developmental Biology
- Cell Biology
- General Biochemistry
- Genetics and Molecular Biology
- Molecular Biology
language:
- iso: eng
month: '10'
oa_version: None
page: 2290-2304.e7
pmid: 1
publication: Developmental Cell
publication_identifier:
issn:
- 1534-5807
publication_status: published
publisher: Elsevier
quality_controlled: '1'
scopus_import: '1'
status: public
title: A feedback loop between lamellipodial extension and HGF-ERK signaling specifies
leader cells during collective cell migration
type: journal_article
user_id: 4359f0d1-fa6c-11eb-b949-802e58b17ae8
volume: 57
year: '2022'
...
---
_id: '12368'
abstract:
- lang: eng
text: "Metazoan development relies on the formation and remodeling of cell-cell
contacts. The \r\nbinding of adhesion receptors and remodeling of the actomyosin
cell cortex at cell-cell \r\ninteraction sites have been implicated in cell-cell
contact formation. Yet, how these two \r\nprocesses functionally interact to drive
cell-cell contact expansion and strengthening \r\nremains unclear. Here, we study
how primary germ layer progenitor cells from zebrafish \r\nbind to supported lipid
bilayers (SLB) functionalized with E-cadherin ectodomains as an \r\nassay system
for monitoring cell-cell contact formation at high spatiotemporal resolution.
\r\nWe show that cell-cell contact formation represents a two-tiered process:
E-cadherin\x02mediated downregulation of the small GTPase RhoA at the forming
contact leads to both \r\ndepletion of Myosin-2 and decrease of F-actin. This
is followed by centrifugal actin \r\nnetwork flows at the contact triggered by
a sharp gradient of Myosin-2 at the rim of the \r\ncontact zone, with Myosin-2
displaying higher cortical localization outside than inside of \r\nthe contact.
These centrifugal cortical actin flows, in turn, not only further dilute the actin
\r\nnetwork at the contact disc, but also lead to an accumulation of both F-actin
and E\x02cadherin at the contact rim. Eventually, this combination of actomyosin
downregulation \r\nand flows at the contact contribute to the characteristic molecular
organization implicated \r\nin contact formation and maintenance: depletion of
cortical actomyosin at the contact disc, \r\ndriving contact expansion by lowering
interfacial tension at the contact, and accumulation \r\nof both E-cadherin and
F-actin at the contact rim, mechanically linking the contractile \r\ncortices
of the adhering cells. Thus, using a biomimetic assay, we exemplify how \r\nadhesion
signaling and cell mechanics function together to modulate the spatial \r\norganization
of cell-cell contacts."
acknowledged_ssus:
- _id: LifeSc
- _id: Bio
- _id: NanoFab
alternative_title:
- ISTA Thesis
article_processing_charge: No
author:
- first_name: Feyza N
full_name: Arslan, Feyza N
id: 49DA7910-F248-11E8-B48F-1D18A9856A87
last_name: Arslan
orcid: 0000-0001-5809-9566
citation:
ama: Arslan FN. Remodeling of E-cadherin-mediated contacts via cortical flows.
2022. doi:10.15479/at:ista:12153
apa: Arslan, F. N. (2022). Remodeling of E-cadherin-mediated contacts via cortical
flows. Institute of Science and Technology Austria. https://doi.org/10.15479/at:ista:12153
chicago: Arslan, Feyza N. “Remodeling of E-Cadherin-Mediated Contacts via Cortical
Flows.” Institute of Science and Technology Austria, 2022. https://doi.org/10.15479/at:ista:12153.
ieee: F. N. Arslan, “Remodeling of E-cadherin-mediated contacts via cortical flows,”
Institute of Science and Technology Austria, 2022.
ista: Arslan FN. 2022. Remodeling of E-cadherin-mediated contacts via cortical
flows. Institute of Science and Technology Austria.
mla: Arslan, Feyza N. Remodeling of E-Cadherin-Mediated Contacts via Cortical
Flows. Institute of Science and Technology Austria, 2022, doi:10.15479/at:ista:12153.
short: F.N. Arslan, Remodeling of E-Cadherin-Mediated Contacts via Cortical Flows,
Institute of Science and Technology Austria, 2022.
date_created: 2023-01-25T10:43:24Z
date_published: 2022-09-29T00:00:00Z
date_updated: 2023-08-08T13:14:10Z
day: '29'
ddc:
- '570'
degree_awarded: PhD
department:
- _id: GradSch
- _id: CaHe
doi: 10.15479/at:ista:12153
ec_funded: 1
file:
- access_level: open_access
checksum: e54a3e69b83ebf166544164afd25608e
content_type: application/pdf
creator: cchlebak
date_created: 2023-01-25T10:52:46Z
date_updated: 2023-01-25T10:52:46Z
file_id: '12369'
file_name: THESIS_FINAL_FArslan_pdfa.pdf
file_size: 14581024
relation: main_file
success: 1
file_date_updated: 2023-01-25T10:52:46Z
has_accepted_license: '1'
language:
- iso: eng
month: '09'
oa: 1
oa_version: Published Version
page: '113'
project:
- _id: 260F1432-B435-11E9-9278-68D0E5697425
call_identifier: H2020
grant_number: '742573'
name: Interaction and feedback between cell mechanics and fate specification in
vertebrate gastrulation
publication_identifier:
isbn:
- ' 978-3-99078-025-1 '
issn:
- 2663-337X
publication_status: published
publisher: Institute of Science and Technology Austria
related_material:
record:
- id: '9350'
relation: part_of_dissertation
status: public
status: public
supervisor:
- first_name: Carl-Philipp J
full_name: Heisenberg, Carl-Philipp J
id: 39427864-F248-11E8-B48F-1D18A9856A87
last_name: Heisenberg
orcid: 0000-0002-0912-4566
title: Remodeling of E-cadherin-mediated contacts via cortical flows
tmp:
image: /images/cc_by.png
legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
short: CC BY (4.0)
type: dissertation
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
year: '2022'
...
---
_id: '9245'
abstract:
- lang: eng
text: Tissue morphogenesis is driven by mechanical forces triggering cell movements
and shape changes. Quantitatively measuring tension within tissues is of great
importance for understanding the role of mechanical signals acting on the cell
and tissue level during morphogenesis. Here we introduce laser ablation as a useful
tool to probe tissue tension within the granulosa layer, an epithelial monolayer
of somatic cells that surround the zebrafish female gamete during folliculogenesis.
We describe in detail how to isolate follicles, mount samples, perform laser surgery,
and analyze the data.
acknowledged_ssus:
- _id: Bio
- _id: PreCl
acknowledgement: We thank Prof. Masazumi Tada and Roland Dosch for providing transgenic
zebrafish lines, the Heisenberg lab for technical assistance and feedback on the
manuscript, and the Bioimaging and Fish facilities of IST Austria for continuous
support. This work was funded by an ERC advanced grant (MECSPEC to C.-P.H.).
alternative_title:
- Methods in Molecular Biology
article_processing_charge: No
author:
- first_name: Peng
full_name: Xia, Peng
id: 4AB6C7D0-F248-11E8-B48F-1D18A9856A87
last_name: Xia
orcid: 0000-0002-5419-7756
- first_name: Carl-Philipp J
full_name: Heisenberg, Carl-Philipp J
id: 39427864-F248-11E8-B48F-1D18A9856A87
last_name: Heisenberg
orcid: 0000-0002-0912-4566
citation:
ama: 'Xia P, Heisenberg C-PJ. Quantifying tissue tension in the granulosa layer
after laser surgery. In: Dosch R, ed. Germline Development in the Zebrafish.
Vol 2218. Humana; 2021:117-128. doi:10.1007/978-1-0716-0970-5_10'
apa: Xia, P., & Heisenberg, C.-P. J. (2021). Quantifying tissue tension in the
granulosa layer after laser surgery. In R. Dosch (Ed.), Germline Development
in the Zebrafish (Vol. 2218, pp. 117–128). Humana. https://doi.org/10.1007/978-1-0716-0970-5_10
chicago: Xia, Peng, and Carl-Philipp J Heisenberg. “Quantifying Tissue Tension in
the Granulosa Layer after Laser Surgery.” In Germline Development in the Zebrafish,
edited by Roland Dosch, 2218:117–28. Humana, 2021. https://doi.org/10.1007/978-1-0716-0970-5_10.
ieee: P. Xia and C.-P. J. Heisenberg, “Quantifying tissue tension in the granulosa
layer after laser surgery,” in Germline Development in the Zebrafish, vol.
2218, R. Dosch, Ed. Humana, 2021, pp. 117–128.
ista: 'Xia P, Heisenberg C-PJ. 2021.Quantifying tissue tension in the granulosa
layer after laser surgery. In: Germline Development in the Zebrafish. Methods
in Molecular Biology, vol. 2218, 117–128.'
mla: Xia, Peng, and Carl-Philipp J. Heisenberg. “Quantifying Tissue Tension in the
Granulosa Layer after Laser Surgery.” Germline Development in the Zebrafish,
edited by Roland Dosch, vol. 2218, Humana, 2021, pp. 117–28, doi:10.1007/978-1-0716-0970-5_10.
short: P. Xia, C.-P.J. Heisenberg, in:, R. Dosch (Ed.), Germline Development in
the Zebrafish, Humana, 2021, pp. 117–128.
date_created: 2021-03-14T23:01:34Z
date_published: 2021-02-20T00:00:00Z
date_updated: 2022-06-03T10:57:55Z
day: '20'
department:
- _id: CaHe
doi: 10.1007/978-1-0716-0970-5_10
ec_funded: 1
editor:
- first_name: Roland
full_name: Dosch, Roland
last_name: Dosch
external_id:
pmid:
- '33606227'
intvolume: ' 2218'
keyword:
- Tissue tension
- Morphogenesis
- Laser ablation
- Zebrafish folliculogenesis
- Granulosa cells
language:
- iso: eng
month: '02'
oa_version: None
page: 117-128
pmid: 1
project:
- _id: 260F1432-B435-11E9-9278-68D0E5697425
call_identifier: H2020
grant_number: '742573'
name: Interaction and feedback between cell mechanics and fate specification in
vertebrate gastrulation
publication: Germline Development in the Zebrafish
publication_identifier:
eisbn:
- 978-1-0716-0970-5
eissn:
- 1940-6029
isbn:
- 978-1-0716-0969-9
issn:
- 1064-3745
publication_status: published
publisher: Humana
quality_controlled: '1'
scopus_import: '1'
status: public
title: Quantifying tissue tension in the granulosa layer after laser surgery
type: book_chapter
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 2218
year: '2021'
...
---
_id: '8966'
abstract:
- lang: eng
text: During development, a single cell is transformed into a highly complex organism
through progressive cell division, specification and rearrangement. An important
prerequisite for the emergence of patterns within the developing organism is to
establish asymmetries at various scales, ranging from individual cells to the
entire embryo, eventually giving rise to the different body structures. This becomes
especially apparent during gastrulation, when the earliest major lineage restriction
events lead to the formation of the different germ layers. Traditionally, the
unfolding of the developmental program from symmetry breaking to germ layer formation
has been studied by dissecting the contributions of different signaling pathways
and cellular rearrangements in the in vivo context of intact embryos. Recent efforts,
using the intrinsic capacity of embryonic stem cells to self-assemble and generate
embryo-like structures de novo, have opened new avenues for understanding the
many ways by which an embryo can be built and the influence of extrinsic factors
therein. Here, we discuss and compare divergent and conserved strategies leading
to germ layer formation in embryos as compared to in vitro systems, their upstream
molecular cascades and the role of extrinsic factors in this process.
acknowledgement: We thank Nicoletta Petridou, Diana Pinheiro, Cornelia Schwayer and
Stefania Tavano for feedback on the manuscript. Research in the Heisenberg lab is
supported by an ERC Advanced Grant (MECSPEC 742573) to C.-P.H. A.S. is a recipient
of a DOC Fellowship of the Austrian Academy of Science.
article_processing_charge: Yes (via OA deal)
article_type: original
author:
- first_name: Alexandra
full_name: Schauer, Alexandra
id: 30A536BA-F248-11E8-B48F-1D18A9856A87
last_name: Schauer
orcid: 0000-0001-7659-9142
- first_name: Carl-Philipp J
full_name: Heisenberg, Carl-Philipp J
id: 39427864-F248-11E8-B48F-1D18A9856A87
last_name: Heisenberg
orcid: 0000-0002-0912-4566
citation:
ama: Schauer A, Heisenberg C-PJ. Reassembling gastrulation. Developmental Biology.
2021;474:71-81. doi:10.1016/j.ydbio.2020.12.014
apa: Schauer, A., & Heisenberg, C.-P. J. (2021). Reassembling gastrulation.
Developmental Biology. Elsevier. https://doi.org/10.1016/j.ydbio.2020.12.014
chicago: Schauer, Alexandra, and Carl-Philipp J Heisenberg. “Reassembling Gastrulation.”
Developmental Biology. Elsevier, 2021. https://doi.org/10.1016/j.ydbio.2020.12.014.
ieee: A. Schauer and C.-P. J. Heisenberg, “Reassembling gastrulation,” Developmental
Biology, vol. 474. Elsevier, pp. 71–81, 2021.
ista: Schauer A, Heisenberg C-PJ. 2021. Reassembling gastrulation. Developmental
Biology. 474, 71–81.
mla: Schauer, Alexandra, and Carl-Philipp J. Heisenberg. “Reassembling Gastrulation.”
Developmental Biology, vol. 474, Elsevier, 2021, pp. 71–81, doi:10.1016/j.ydbio.2020.12.014.
short: A. Schauer, C.-P.J. Heisenberg, Developmental Biology 474 (2021) 71–81.
date_created: 2020-12-22T09:53:34Z
date_published: 2021-06-01T00:00:00Z
date_updated: 2023-08-07T13:30:01Z
day: '01'
ddc:
- '570'
department:
- _id: CaHe
doi: 10.1016/j.ydbio.2020.12.014
ec_funded: 1
external_id:
isi:
- '000639461800008'
file:
- access_level: open_access
checksum: fa2a5731fd16ab171b029f32f031c440
content_type: application/pdf
creator: kschuh
date_created: 2021-08-11T10:28:06Z
date_updated: 2021-08-11T10:28:06Z
file_id: '9880'
file_name: 2021_DevBiology_Schauer.pdf
file_size: 1440321
relation: main_file
success: 1
file_date_updated: 2021-08-11T10:28:06Z
has_accepted_license: '1'
intvolume: ' 474'
isi: 1
keyword:
- Developmental Biology
- Cell Biology
- Molecular Biology
language:
- iso: eng
month: '06'
oa: 1
oa_version: Published Version
page: 71-81
project:
- _id: 260F1432-B435-11E9-9278-68D0E5697425
call_identifier: H2020
grant_number: '742573'
name: Interaction and feedback between cell mechanics and fate specification in
vertebrate gastrulation
- _id: 26B1E39C-B435-11E9-9278-68D0E5697425
grant_number: '25239'
name: 'Mesendoderm specification in zebrafish: The role of extraembryonic tissues'
publication: Developmental Biology
publication_identifier:
issn:
- 0012-1606
publication_status: published
publisher: Elsevier
quality_controlled: '1'
related_material:
record:
- id: '12891'
relation: dissertation_contains
status: public
scopus_import: '1'
status: public
title: Reassembling gastrulation
tmp:
image: /images/cc_by_nc_nd.png
legal_code_url: https://creativecommons.org/licenses/by-nc-nd/4.0/legalcode
name: Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International
(CC BY-NC-ND 4.0)
short: CC BY-NC-ND (4.0)
type: journal_article
user_id: 4359f0d1-fa6c-11eb-b949-802e58b17ae8
volume: 474
year: '2021'
...
---
_id: '9316'
abstract:
- lang: eng
text: Embryo morphogenesis is impacted by dynamic changes in tissue material properties,
which have been proposed to occur via processes akin to phase transitions (PTs).
Here, we show that rigidity percolation provides a simple and robust theoretical
framework to predict material/structural PTs of embryonic tissues from local cell
connectivity. By using percolation theory, combined with directly monitoring dynamic
changes in tissue rheology and cell contact mechanics, we demonstrate that the
zebrafish blastoderm undergoes a genuine rigidity PT, brought about by a small
reduction in adhesion-dependent cell connectivity below a critical value. We quantitatively
predict and experimentally verify hallmarks of PTs, including power-law exponents
and associated discontinuities of macroscopic observables. Finally, we show that
this uniform PT depends on blastoderm cells undergoing meta-synchronous divisions
causing random and, consequently, uniform changes in cell connectivity. Collectively,
our theoretical and experimental findings reveal the structural basis of material
PTs in an organismal context.
acknowledged_ssus:
- _id: Bio
- _id: PreCl
acknowledgement: We thank Carl Goodrich and the members of the Heisenberg and Hannezo
groups, in particular Reka Korei, for help, technical advice, and discussions; and
the Bioimaging and zebrafish facilities of the IST Austria for continuous support.
This work was supported by the Elise Richter Program of Austrian Science Fund (FWF)
to N.I.P. ( V 736-B26 ) and the European Union (European Research Council Advanced
Grant 742573 to C.-P.H. and European Research Council Starting Grant 851288 to E.H.).
article_processing_charge: No
article_type: original
author:
- first_name: Nicoletta
full_name: Petridou, Nicoletta
id: 2A003F6C-F248-11E8-B48F-1D18A9856A87
last_name: Petridou
orcid: 0000-0002-8451-1195
- first_name: Bernat
full_name: Corominas-Murtra, Bernat
id: 43BE2298-F248-11E8-B48F-1D18A9856A87
last_name: Corominas-Murtra
orcid: 0000-0001-9806-5643
- first_name: Carl-Philipp J
full_name: Heisenberg, Carl-Philipp J
id: 39427864-F248-11E8-B48F-1D18A9856A87
last_name: Heisenberg
orcid: 0000-0002-0912-4566
- first_name: Edouard B
full_name: Hannezo, Edouard B
id: 3A9DB764-F248-11E8-B48F-1D18A9856A87
last_name: Hannezo
orcid: 0000-0001-6005-1561
citation:
ama: Petridou N, Corominas-Murtra B, Heisenberg C-PJ, Hannezo EB. Rigidity percolation
uncovers a structural basis for embryonic tissue phase transitions. Cell.
2021;184(7):1914-1928.e19. doi:10.1016/j.cell.2021.02.017
apa: Petridou, N., Corominas-Murtra, B., Heisenberg, C.-P. J., & Hannezo, E.
B. (2021). Rigidity percolation uncovers a structural basis for embryonic tissue
phase transitions. Cell. Elsevier. https://doi.org/10.1016/j.cell.2021.02.017
chicago: Petridou, Nicoletta, Bernat Corominas-Murtra, Carl-Philipp J Heisenberg,
and Edouard B Hannezo. “Rigidity Percolation Uncovers a Structural Basis for Embryonic
Tissue Phase Transitions.” Cell. Elsevier, 2021. https://doi.org/10.1016/j.cell.2021.02.017.
ieee: N. Petridou, B. Corominas-Murtra, C.-P. J. Heisenberg, and E. B. Hannezo,
“Rigidity percolation uncovers a structural basis for embryonic tissue phase transitions,”
Cell, vol. 184, no. 7. Elsevier, p. 1914–1928.e19, 2021.
ista: Petridou N, Corominas-Murtra B, Heisenberg C-PJ, Hannezo EB. 2021. Rigidity
percolation uncovers a structural basis for embryonic tissue phase transitions.
Cell. 184(7), 1914–1928.e19.
mla: Petridou, Nicoletta, et al. “Rigidity Percolation Uncovers a Structural Basis
for Embryonic Tissue Phase Transitions.” Cell, vol. 184, no. 7, Elsevier,
2021, p. 1914–1928.e19, doi:10.1016/j.cell.2021.02.017.
short: N. Petridou, B. Corominas-Murtra, C.-P.J. Heisenberg, E.B. Hannezo, Cell
184 (2021) 1914–1928.e19.
date_created: 2021-04-11T22:01:14Z
date_published: 2021-04-01T00:00:00Z
date_updated: 2023-08-07T14:33:59Z
day: '01'
ddc:
- '570'
department:
- _id: CaHe
- _id: EdHa
doi: 10.1016/j.cell.2021.02.017
ec_funded: 1
external_id:
isi:
- '000636734000022'
pmid:
- '33730596'
file:
- access_level: open_access
checksum: 1e5295fbd9c2a459173ec45a0e8a7c2e
content_type: application/pdf
creator: cziletti
date_created: 2021-06-08T10:04:10Z
date_updated: 2021-06-08T10:04:10Z
file_id: '9534'
file_name: 2021_Cell_Petridou.pdf
file_size: 11405875
relation: main_file
success: 1
file_date_updated: 2021-06-08T10:04:10Z
has_accepted_license: '1'
intvolume: ' 184'
isi: 1
issue: '7'
language:
- iso: eng
month: '04'
oa: 1
oa_version: Published Version
page: 1914-1928.e19
pmid: 1
project:
- _id: 260F1432-B435-11E9-9278-68D0E5697425
call_identifier: H2020
grant_number: '742573'
name: Interaction and feedback between cell mechanics and fate specification in
vertebrate gastrulation
- _id: 05943252-7A3F-11EA-A408-12923DDC885E
call_identifier: H2020
grant_number: '851288'
name: Design Principles of Branching Morphogenesis
- _id: 2693FD8C-B435-11E9-9278-68D0E5697425
call_identifier: FWF
grant_number: V00736
name: Tissue material properties in embryonic development
publication: Cell
publication_identifier:
eissn:
- '10974172'
issn:
- '00928674'
publication_status: published
publisher: Elsevier
quality_controlled: '1'
related_material:
link:
- description: News on IST Homepage
relation: press_release
url: https://ist.ac.at/en/news/embryonic-tissue-undergoes-phase-transition/
scopus_import: '1'
status: public
title: Rigidity percolation uncovers a structural basis for embryonic tissue phase
transitions
tmp:
image: /images/cc_by.png
legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
short: CC BY (4.0)
type: journal_article
user_id: 4359f0d1-fa6c-11eb-b949-802e58b17ae8
volume: 184
year: '2021'
...
---
_id: '9336'
abstract:
- lang: eng
text: Mentorship is experience and/or knowledge‐based guidance. Mentors support,
sponsor and advocate for mentees. Having one or more mentors when you seek advice
can significantly influence and improve your research endeavours, well‐being and
career development. Positive mentee–mentor relationships are vital for maintaining
work–life balance and success in careers. Early‐career researchers (ECRs), in
particular, can benefit from mentorship to navigate challenges in academic and
nonacademic life and careers. Yet, strategies for selecting mentors and maintaining
interactions with them are often underdiscussed within research environments.
In this Words of Advice, we provide recommendations for ECRs to seek and manage
mentorship interactions. Our article draws from our experiences as ECRs and published
work, to provide suggestions for mentees to proactively promote beneficial mentorship
interactions. The recommended practices highlight the importance of identifying
mentorship needs, planning and selecting multiple and diverse mentors, setting
goals, and maintaining constructive, and mutually beneficial working relationships
with mentors.
acknowledgement: The authors thank Nicholas Asby of the University of Chicago for
valuable comments on an earlier version of this work. A.P.S. was partially supported
by the NARSAD Young Investigator Grant 27705. S.J.H was supported by the National
Institutes of Health grant R35GM133732.
alternative_title:
- Words of Advice
article_processing_charge: No
article_type: original
author:
- first_name: Sarvenaz
full_name: Sarabipour, Sarvenaz
last_name: Sarabipour
- first_name: Sarah J.
full_name: Hainer, Sarah J.
last_name: Hainer
- first_name: Feyza N
full_name: Arslan, Feyza N
id: 49DA7910-F248-11E8-B48F-1D18A9856A87
last_name: Arslan
orcid: 0000-0001-5809-9566
- first_name: Charlotte M.
full_name: De Winde, Charlotte M.
last_name: De Winde
- first_name: Emily
full_name: Furlong, Emily
last_name: Furlong
- first_name: Natalia
full_name: Bielczyk, Natalia
last_name: Bielczyk
- first_name: Nafisa M.
full_name: Jadavji, Nafisa M.
last_name: Jadavji
- first_name: Aparna P.
full_name: Shah, Aparna P.
last_name: Shah
- first_name: Sejal
full_name: Davla, Sejal
last_name: Davla
citation:
ama: Sarabipour S, Hainer SJ, Arslan FN, et al. Building and sustaining mentor interactions
as a mentee. FEBS Journal. 2021. doi:10.1111/febs.15823
apa: Sarabipour, S., Hainer, S. J., Arslan, F. N., De Winde, C. M., Furlong, E.,
Bielczyk, N., … Davla, S. (2021). Building and sustaining mentor interactions
as a mentee. FEBS Journal. Wiley. https://doi.org/10.1111/febs.15823
chicago: Sarabipour, Sarvenaz, Sarah J. Hainer, Feyza N Arslan, Charlotte M. De
Winde, Emily Furlong, Natalia Bielczyk, Nafisa M. Jadavji, Aparna P. Shah, and
Sejal Davla. “Building and Sustaining Mentor Interactions as a Mentee.” FEBS
Journal. Wiley, 2021. https://doi.org/10.1111/febs.15823.
ieee: S. Sarabipour et al., “Building and sustaining mentor interactions
as a mentee,” FEBS Journal. Wiley, 2021.
ista: Sarabipour S, Hainer SJ, Arslan FN, De Winde CM, Furlong E, Bielczyk N, Jadavji
NM, Shah AP, Davla S. 2021. Building and sustaining mentor interactions as a mentee.
FEBS Journal.
mla: Sarabipour, Sarvenaz, et al. “Building and Sustaining Mentor Interactions as
a Mentee.” FEBS Journal, Wiley, 2021, doi:10.1111/febs.15823.
short: S. Sarabipour, S.J. Hainer, F.N. Arslan, C.M. De Winde, E. Furlong, N. Bielczyk,
N.M. Jadavji, A.P. Shah, S. Davla, FEBS Journal (2021).
date_created: 2021-04-18T22:01:43Z
date_published: 2021-04-05T00:00:00Z
date_updated: 2023-08-08T13:12:55Z
day: '05'
department:
- _id: CaHe
doi: 10.1111/febs.15823
external_id:
isi:
- '000636678800001'
pmid:
- '33818917'
isi: 1
language:
- iso: eng
main_file_link:
- open_access: '1'
url: https://doi.org/10.1111/febs.15823
month: '04'
oa: 1
oa_version: Published Version
pmid: 1
publication: FEBS Journal
publication_identifier:
eissn:
- 1742-4658
issn:
- 1742-464X
publication_status: published
publisher: Wiley
quality_controlled: '1'
scopus_import: '1'
status: public
title: Building and sustaining mentor interactions as a mentee
type: journal_article
user_id: 4359f0d1-fa6c-11eb-b949-802e58b17ae8
year: '2021'
...
---
_id: '9350'
abstract:
- lang: eng
text: Intercellular adhesion is the key to multicellularity, and its malfunction
plays an important role in various developmental and disease-related processes.
Although it has been intensively studied by both biologists and physicists, a
commonly accepted definition of cell-cell adhesion is still being debated. Cell-cell
adhesion has been described at the molecular scale as a function of adhesion receptors
controlling binding affinity, at the cellular scale as resistance to detachment
forces or modulation of surface tension, and at the tissue scale as a regulator
of cellular rearrangements and morphogenesis. In this review, we aim to summarize
and discuss recent advances in the molecular, cellular, and theoretical description
of cell-cell adhesion, ranging from biomimetic models to the complexity of cells
and tissues in an organismal context. In particular, we will focus on cadherin-mediated
cell-cell adhesion and the role of adhesion signaling and mechanosensation therein,
two processes central for understanding the biological and physical basis of cell-cell
adhesion.
acknowledgement: T.S. acknowledges funding by the research program “The Active Matter
Physics of Collective Metastasis,” which is financed by the Dutch Research Council
(NWO).
article_processing_charge: No
article_type: original
author:
- first_name: Feyza N
full_name: Arslan, Feyza N
id: 49DA7910-F248-11E8-B48F-1D18A9856A87
last_name: Arslan
orcid: 0000-0001-5809-9566
- first_name: Julia
full_name: Eckert, Julia
last_name: Eckert
- first_name: Thomas
full_name: Schmidt, Thomas
last_name: Schmidt
- first_name: Carl-Philipp J
full_name: Heisenberg, Carl-Philipp J
id: 39427864-F248-11E8-B48F-1D18A9856A87
last_name: Heisenberg
orcid: 0000-0002-0912-4566
citation:
ama: 'Arslan FN, Eckert J, Schmidt T, Heisenberg C-PJ. Holding it together: when
cadherin meets cadherin. Biophysical Journal. 2021;120:4182-4192. doi:10.1016/j.bpj.2021.03.025'
apa: 'Arslan, F. N., Eckert, J., Schmidt, T., & Heisenberg, C.-P. J. (2021).
Holding it together: when cadherin meets cadherin. Biophysical Journal.
Biophysical Society. https://doi.org/10.1016/j.bpj.2021.03.025'
chicago: 'Arslan, Feyza N, Julia Eckert, Thomas Schmidt, and Carl-Philipp J Heisenberg.
“Holding It Together: When Cadherin Meets Cadherin.” Biophysical Journal.
Biophysical Society, 2021. https://doi.org/10.1016/j.bpj.2021.03.025.'
ieee: 'F. N. Arslan, J. Eckert, T. Schmidt, and C.-P. J. Heisenberg, “Holding it
together: when cadherin meets cadherin,” Biophysical Journal, vol. 120.
Biophysical Society, pp. 4182–4192, 2021.'
ista: 'Arslan FN, Eckert J, Schmidt T, Heisenberg C-PJ. 2021. Holding it together:
when cadherin meets cadherin. Biophysical Journal. 120, 4182–4192.'
mla: 'Arslan, Feyza N., et al. “Holding It Together: When Cadherin Meets Cadherin.”
Biophysical Journal, vol. 120, Biophysical Society, 2021, pp. 4182–92,
doi:10.1016/j.bpj.2021.03.025.'
short: F.N. Arslan, J. Eckert, T. Schmidt, C.-P.J. Heisenberg, Biophysical Journal
120 (2021) 4182–4192.
date_created: 2021-04-25T22:01:30Z
date_published: 2021-10-05T00:00:00Z
date_updated: 2023-08-08T13:14:10Z
day: '05'
department:
- _id: CaHe
doi: 10.1016/j.bpj.2021.03.025
external_id:
isi:
- '000704646900006'
pmid:
- '33794149'
intvolume: ' 120'
isi: 1
language:
- iso: eng
main_file_link:
- open_access: '1'
url: https://scholarlypublications.universiteitleiden.nl/access/item%3A3251048/view
month: '10'
oa: 1
oa_version: Published Version
page: 4182-4192
pmid: 1
publication: Biophysical Journal
publication_identifier:
eissn:
- 1542-0086
issn:
- 0006-3495
publication_status: published
publisher: Biophysical Society
quality_controlled: '1'
related_material:
record:
- id: '12368'
relation: dissertation_contains
status: public
scopus_import: '1'
status: public
title: 'Holding it together: when cadherin meets cadherin'
type: journal_article
user_id: 4359f0d1-fa6c-11eb-b949-802e58b17ae8
volume: 120
year: '2021'
...
---
_id: '9759'
acknowledgement: The authors thank Inez Lam of Johns Hopkins University for valuable
comments on an earlier version of the manuscript. We also thank the facilitators
of the 2019–2020 eLife Community Ambassador program.
article_number: e1009124
article_processing_charge: Yes
article_type: letter_note
author:
- first_name: Michael John
full_name: Bartlett, Michael John
last_name: Bartlett
- first_name: Feyza N
full_name: Arslan, Feyza N
id: 49DA7910-F248-11E8-B48F-1D18A9856A87
last_name: Arslan
orcid: 0000-0001-5809-9566
- first_name: Adriana
full_name: Bankston, Adriana
last_name: Bankston
- first_name: Sarvenaz
full_name: Sarabipour, Sarvenaz
last_name: Sarabipour
citation:
ama: Bartlett MJ, Arslan FN, Bankston A, Sarabipour S. Ten simple rules to improve
academic work- life balance. PLoS Computational Biology. 2021;17(7). doi:10.1371/journal.pcbi.1009124
apa: Bartlett, M. J., Arslan, F. N., Bankston, A., & Sarabipour, S. (2021).
Ten simple rules to improve academic work- life balance. PLoS Computational
Biology. Public Library of Science. https://doi.org/10.1371/journal.pcbi.1009124
chicago: Bartlett, Michael John, Feyza N Arslan, Adriana Bankston, and Sarvenaz
Sarabipour. “Ten Simple Rules to Improve Academic Work- Life Balance.” PLoS
Computational Biology. Public Library of Science, 2021. https://doi.org/10.1371/journal.pcbi.1009124.
ieee: M. J. Bartlett, F. N. Arslan, A. Bankston, and S. Sarabipour, “Ten simple
rules to improve academic work- life balance,” PLoS Computational Biology,
vol. 17, no. 7. Public Library of Science, 2021.
ista: Bartlett MJ, Arslan FN, Bankston A, Sarabipour S. 2021. Ten simple rules to
improve academic work- life balance. PLoS Computational Biology. 17(7), e1009124.
mla: Bartlett, Michael John, et al. “Ten Simple Rules to Improve Academic Work-
Life Balance.” PLoS Computational Biology, vol. 17, no. 7, e1009124, Public
Library of Science, 2021, doi:10.1371/journal.pcbi.1009124.
short: M.J. Bartlett, F.N. Arslan, A. Bankston, S. Sarabipour, PLoS Computational
Biology 17 (2021).
date_created: 2021-08-01T22:01:21Z
date_published: 2021-07-15T00:00:00Z
date_updated: 2023-08-10T14:16:46Z
day: '15'
ddc:
- '613'
department:
- _id: CaHe
doi: 10.1371/journal.pcbi.1009124
external_id:
isi:
- '000677713500008'
pmid:
- '34264932'
file:
- access_level: open_access
checksum: e56d91f0eeadb36f143a90e2c1b3ab63
content_type: application/pdf
creator: cchlebak
date_created: 2021-08-05T12:06:49Z
date_updated: 2021-08-05T12:06:49Z
file_id: '9771'
file_name: 2021_PlosCompBio_Bartlett.pdf
file_size: 693633
relation: main_file
file_date_updated: 2021-08-05T12:06:49Z
has_accepted_license: '1'
intvolume: ' 17'
isi: 1
issue: '7'
language:
- iso: eng
month: '07'
oa: 1
oa_version: Published Version
pmid: 1
publication: PLoS Computational Biology
publication_identifier:
eissn:
- '15537358'
issn:
- 1553734X
publication_status: published
publisher: Public Library of Science
scopus_import: '1'
status: public
title: Ten simple rules to improve academic work- life balance
tmp:
image: /images/cc_by.png
legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
short: CC BY (4.0)
type: journal_article
user_id: 4359f0d1-fa6c-11eb-b949-802e58b17ae8
volume: 17
year: '2021'
...
---
_id: '9999'
abstract:
- lang: eng
text: 'The developmental strategies used by progenitor cells to endure a safe journey
from their induction place towards the site of terminal differentiation are still
poorly understood. Here we uncovered a progenitor cell allocation mechanism that
stems from an incomplete process of epithelial delamination that allows progenitors
to coordinate their movement with adjacent extra-embryonic tissues. Progenitors
of the zebrafish laterality organ originate from the surface epithelial enveloping
layer by an apical constriction process of cell delamination. During this process,
progenitors retain long-term apical contacts that enable the epithelial layer
to pull a subset of progenitors along their way towards the vegetal pole. The
remaining delaminated progenitors follow apically-attached progenitors’ movement
by a co-attraction mechanism, avoiding sequestration by the adjacent endoderm,
ensuring their fate and collective allocation at the differentiation site. Thus,
we reveal that incomplete delamination serves as a cellular platform for coordinated
tissue movements during development. Impact Statement: Incomplete delamination
serves as a cellular platform for coordinated tissue movements during development,
guiding newly formed progenitor cell groups to the differentiation site.'
article_number: e66483
article_processing_charge: Yes
article_type: original
author:
- first_name: Eduardo
full_name: Pulgar, Eduardo
last_name: Pulgar
- first_name: Cornelia
full_name: Schwayer, Cornelia
id: 3436488C-F248-11E8-B48F-1D18A9856A87
last_name: Schwayer
orcid: 0000-0001-5130-2226
- first_name: Néstor
full_name: Guerrero, Néstor
last_name: Guerrero
- first_name: Loreto
full_name: López, Loreto
last_name: López
- first_name: Susana
full_name: Márquez, Susana
last_name: Márquez
- first_name: Steffen
full_name: Härtel, Steffen
last_name: Härtel
- first_name: Rodrigo
full_name: Soto, Rodrigo
last_name: Soto
- first_name: Carl Philipp
full_name: Heisenberg, Carl Philipp
last_name: Heisenberg
- first_name: Miguel L.
full_name: Concha, Miguel L.
last_name: Concha
citation:
ama: Pulgar E, Schwayer C, Guerrero N, et al. Apical contacts stemming from incomplete
delamination guide progenitor cell allocation through a dragging mechanism. eLife.
2021;10. doi:10.7554/eLife.66483
apa: Pulgar, E., Schwayer, C., Guerrero, N., López, L., Márquez, S., Härtel, S.,
… Concha, M. L. (2021). Apical contacts stemming from incomplete delamination
guide progenitor cell allocation through a dragging mechanism. ELife. eLife
Sciences Publications. https://doi.org/10.7554/eLife.66483
chicago: Pulgar, Eduardo, Cornelia Schwayer, Néstor Guerrero, Loreto López, Susana
Márquez, Steffen Härtel, Rodrigo Soto, Carl Philipp Heisenberg, and Miguel L.
Concha. “Apical Contacts Stemming from Incomplete Delamination Guide Progenitor
Cell Allocation through a Dragging Mechanism.” ELife. eLife Sciences Publications,
2021. https://doi.org/10.7554/eLife.66483.
ieee: E. Pulgar et al., “Apical contacts stemming from incomplete delamination
guide progenitor cell allocation through a dragging mechanism,” eLife,
vol. 10. eLife Sciences Publications, 2021.
ista: Pulgar E, Schwayer C, Guerrero N, López L, Márquez S, Härtel S, Soto R, Heisenberg
CP, Concha ML. 2021. Apical contacts stemming from incomplete delamination guide
progenitor cell allocation through a dragging mechanism. eLife. 10, e66483.
mla: Pulgar, Eduardo, et al. “Apical Contacts Stemming from Incomplete Delamination
Guide Progenitor Cell Allocation through a Dragging Mechanism.” ELife,
vol. 10, e66483, eLife Sciences Publications, 2021, doi:10.7554/eLife.66483.
short: E. Pulgar, C. Schwayer, N. Guerrero, L. López, S. Márquez, S. Härtel, R.
Soto, C.P. Heisenberg, M.L. Concha, ELife 10 (2021).
date_created: 2021-09-12T22:01:23Z
date_published: 2021-08-27T00:00:00Z
date_updated: 2023-08-14T06:53:33Z
day: '27'
ddc:
- '570'
department:
- _id: CaHe
doi: 10.7554/eLife.66483
ec_funded: 1
external_id:
isi:
- '000700428500001'
pmid:
- '34448451'
file:
- access_level: open_access
checksum: a3f82b0499cc822ac1eab48a01f3f57e
content_type: application/pdf
creator: dernst
date_created: 2022-05-13T08:03:37Z
date_updated: 2022-05-13T08:03:37Z
file_id: '11371'
file_name: 2021_eLife_Pulgar.pdf
file_size: 9010446
relation: main_file
success: 1
file_date_updated: 2022-05-13T08:03:37Z
has_accepted_license: '1'
intvolume: ' 10'
isi: 1
keyword:
- cell delamination
- apical constriction
- dragging
- mechanical forces
- collective 18 locomotion
- dorsal forerunner cells
- zebrafish
language:
- iso: eng
month: '08'
oa: 1
oa_version: Published Version
pmid: 1
project:
- _id: 260F1432-B435-11E9-9278-68D0E5697425
call_identifier: H2020
grant_number: '742573'
name: Interaction and feedback between cell mechanics and fate specification in
vertebrate gastrulation
publication: eLife
publication_identifier:
eissn:
- 2050-084X
publication_status: published
publisher: eLife Sciences Publications
quality_controlled: '1'
scopus_import: '1'
status: public
title: Apical contacts stemming from incomplete delamination guide progenitor cell
allocation through a dragging mechanism
tmp:
image: /images/cc_by.png
legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
short: CC BY (4.0)
type: journal_article
user_id: 4359f0d1-fa6c-11eb-b949-802e58b17ae8
volume: 10
year: '2021'
...
---
_id: '10202'
abstract:
- lang: eng
text: Zygotic genome activation (ZGA) initiates regionalized transcription underlying
distinct cellular identities. ZGA is dependent upon dynamic chromatin architecture
sculpted by conserved DNA-binding proteins. However, the direct mechanistic link
between the onset of ZGA and the tissue-specific transcription remains unclear.
Here, we have addressed the involvement of chromatin organizer Satb2 in orchestrating
both processes during zebrafish embryogenesis. Integrative analysis of transcriptome,
genome-wide occupancy and chromatin accessibility reveals contrasting molecular
activities of maternally deposited and zygotically synthesized Satb2. Maternal
Satb2 prevents premature transcription of zygotic genes by influencing the interplay
between the pluripotency factors. By contrast, zygotic Satb2 activates transcription
of the same group of genes during neural crest development and organogenesis.
Thus, our comparative analysis of maternal versus zygotic function of Satb2 underscores
how these antithetical activities are temporally coordinated and functionally
implemented highlighting the evolutionary implications of the biphasic and bimodal
regulation of landmark developmental transitions by a single determinant.
acknowledgement: 'We are grateful to the members of C.-P.H. and SG lab for discussions.
Authors thank Shubha Tole for providing embryonic mouse tissues. Authors are grateful
to Alessandro Mongera and Chetana Sachidanandan for generous help with Tg: Sox10:
GFP line. Authors would like to thank Satyajeet Khare, Vanessa Barone, Jyothish
S., Shalini Mishra, Yoshita Bhide, and Keshav Jha for assistance in experiments.
We would also like to thank Chaitanya Dingare for valuable suggestions. We thank
Diana Pinhiero and Alexandra Schauer for critical reading of early versions of the
manuscript. This work was supported by the Centre of Excellence in Epigenetics program
of the Department of Biotechnology, Government of India Phase I (BT/01/COE/09/07)
to S.G. and R.K.M., and Phase II (BT/COE/34/SP17426/2016) to S.G. and JC Bose Fellowship
(JCB/2019/000013) from Science and Engineering Research Board, Government of India
to S.G., DST-BMWF Indo-Austrian bilateral program grant to S.G. and C.-P.H. The
work using animal models was partly supported by the infrastructure support grants
from the Department of Biotechnology (National Facility for Laboratory Model Organisms:
BT/INF/22/SP17358/2016 and Establishment of a Pune Biotech Cluster, Model Organism
to Human Disease: B-2 Whole Animal Imaging & Tissue Processing FacilityBT/Pune-Biocluster/01/2015).
S.J.P. was supported by Fellowship from the Council of Scientific and Industrial
Research, India and travel fellowship from the Company of Biologists, UK. P.C.R.
was supported by the Early Career Fellowship of the Wellcome Trust-DBT India Alliance
(IA/E/16/1/503057). A.S. was supported by UGC and R.S. was supported by CSIR India.
M.S. was supported by core funding from the Tata Institute of Fundamental Research
(TIFR 12P-121).'
article_number: '6094'
article_processing_charge: Yes
article_type: original
author:
- first_name: Saurabh J.
full_name: Pradhan, Saurabh J.
last_name: Pradhan
- first_name: Puli Chandramouli
full_name: Reddy, Puli Chandramouli
last_name: Reddy
- first_name: Michael
full_name: Smutny, Michael
id: 3FE6E4E8-F248-11E8-B48F-1D18A9856A87
last_name: Smutny
orcid: 0000-0002-5920-9090
- first_name: Ankita
full_name: Sharma, Ankita
last_name: Sharma
- first_name: Keisuke
full_name: Sako, Keisuke
id: 3BED66BE-F248-11E8-B48F-1D18A9856A87
last_name: Sako
orcid: 0000-0002-6453-8075
- first_name: Meghana S.
full_name: Oak, Meghana S.
last_name: Oak
- first_name: Rini
full_name: Shah, Rini
last_name: Shah
- first_name: Mrinmoy
full_name: Pal, Mrinmoy
last_name: Pal
- first_name: Ojas
full_name: Deshpande, Ojas
last_name: Deshpande
- first_name: Greg
full_name: Dsilva, Greg
last_name: Dsilva
- first_name: Yin
full_name: Tang, Yin
last_name: Tang
- first_name: Rakesh
full_name: Mishra, Rakesh
last_name: Mishra
- first_name: Girish
full_name: Deshpande, Girish
last_name: Deshpande
- first_name: Antonio J.
full_name: Giraldez, Antonio J.
last_name: Giraldez
- first_name: Mahendra
full_name: Sonawane, Mahendra
last_name: Sonawane
- first_name: Carl-Philipp J
full_name: Heisenberg, Carl-Philipp J
id: 39427864-F248-11E8-B48F-1D18A9856A87
last_name: Heisenberg
orcid: 0000-0002-0912-4566
- first_name: Sanjeev
full_name: Galande, Sanjeev
last_name: Galande
citation:
ama: Pradhan SJ, Reddy PC, Smutny M, et al. Satb2 acts as a gatekeeper for major
developmental transitions during early vertebrate embryogenesis. Nature Communications.
2021;12(1). doi:10.1038/s41467-021-26234-7
apa: Pradhan, S. J., Reddy, P. C., Smutny, M., Sharma, A., Sako, K., Oak, M. S.,
… Galande, S. (2021). Satb2 acts as a gatekeeper for major developmental transitions
during early vertebrate embryogenesis. Nature Communications. Springer
Nature. https://doi.org/10.1038/s41467-021-26234-7
chicago: Pradhan, Saurabh J., Puli Chandramouli Reddy, Michael Smutny, Ankita Sharma,
Keisuke Sako, Meghana S. Oak, Rini Shah, et al. “Satb2 Acts as a Gatekeeper for
Major Developmental Transitions during Early Vertebrate Embryogenesis.” Nature
Communications. Springer Nature, 2021. https://doi.org/10.1038/s41467-021-26234-7.
ieee: S. J. Pradhan et al., “Satb2 acts as a gatekeeper for major developmental
transitions during early vertebrate embryogenesis,” Nature Communications,
vol. 12, no. 1. Springer Nature, 2021.
ista: Pradhan SJ, Reddy PC, Smutny M, Sharma A, Sako K, Oak MS, Shah R, Pal M, Deshpande
O, Dsilva G, Tang Y, Mishra R, Deshpande G, Giraldez AJ, Sonawane M, Heisenberg
C-PJ, Galande S. 2021. Satb2 acts as a gatekeeper for major developmental transitions
during early vertebrate embryogenesis. Nature Communications. 12(1), 6094.
mla: Pradhan, Saurabh J., et al. “Satb2 Acts as a Gatekeeper for Major Developmental
Transitions during Early Vertebrate Embryogenesis.” Nature Communications,
vol. 12, no. 1, 6094, Springer Nature, 2021, doi:10.1038/s41467-021-26234-7.
short: S.J. Pradhan, P.C. Reddy, M. Smutny, A. Sharma, K. Sako, M.S. Oak, R. Shah,
M. Pal, O. Deshpande, G. Dsilva, Y. Tang, R. Mishra, G. Deshpande, A.J. Giraldez,
M. Sonawane, C.-P.J. Heisenberg, S. Galande, Nature Communications 12 (2021).
date_created: 2021-10-31T23:01:29Z
date_published: 2021-10-19T00:00:00Z
date_updated: 2023-08-14T10:32:48Z
day: '19'
ddc:
- '570'
department:
- _id: CaHe
doi: 10.1038/s41467-021-26234-7
external_id:
isi:
- '000709050300016'
pmid:
- '34667153'
file:
- access_level: open_access
checksum: c40a69ae94435ecd3a30c9874a11ef2b
content_type: application/pdf
creator: cziletti
date_created: 2021-11-09T13:59:26Z
date_updated: 2021-11-09T13:59:26Z
file_id: '10262'
file_name: 2021_NatureComm_Pradhan.pdf
file_size: 7144437
relation: main_file
success: 1
file_date_updated: 2021-11-09T13:59:26Z
has_accepted_license: '1'
intvolume: ' 12'
isi: 1
issue: '1'
language:
- iso: eng
month: '10'
oa: 1
oa_version: Published Version
pmid: 1
publication: Nature Communications
publication_identifier:
eissn:
- '20411723'
publication_status: published
publisher: Springer Nature
quality_controlled: '1'
related_material:
link:
- description: Preprint
relation: earlier_version
url: 'https://doi.org/10.1101/2020.11.23.394171 '
scopus_import: '1'
status: public
title: Satb2 acts as a gatekeeper for major developmental transitions during early
vertebrate embryogenesis
tmp:
image: /images/cc_by.png
legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
short: CC BY (4.0)
type: journal_article
user_id: 4359f0d1-fa6c-11eb-b949-802e58b17ae8
volume: 12
year: '2021'
...
---
_id: '10366'
article_number: '203758'
article_processing_charge: No
article_type: letter_note
author:
- first_name: Carl-Philipp J
full_name: Heisenberg, Carl-Philipp J
id: 39427864-F248-11E8-B48F-1D18A9856A87
last_name: Heisenberg
orcid: 0000-0002-0912-4566
- first_name: Ana Maria
full_name: Lennon, Ana Maria
last_name: Lennon
- first_name: Roberto
full_name: Mayor, Roberto
last_name: Mayor
- first_name: Guillaume
full_name: Salbreux, Guillaume
last_name: Salbreux
citation:
ama: 'Heisenberg C-PJ, Lennon AM, Mayor R, Salbreux G. Special rebranding issue:
“Quantitative cell and developmental biology.” Cells and Development. 2021;168(12).
doi:10.1016/j.cdev.2021.203758'
apa: 'Heisenberg, C.-P. J., Lennon, A. M., Mayor, R., & Salbreux, G. (2021).
Special rebranding issue: “Quantitative cell and developmental biology.” Cells
and Development. Elsevier. https://doi.org/10.1016/j.cdev.2021.203758'
chicago: 'Heisenberg, Carl-Philipp J, Ana Maria Lennon, Roberto Mayor, and Guillaume
Salbreux. “Special Rebranding Issue: ‘Quantitative Cell and Developmental Biology.’”
Cells and Development. Elsevier, 2021. https://doi.org/10.1016/j.cdev.2021.203758.'
ieee: 'C.-P. J. Heisenberg, A. M. Lennon, R. Mayor, and G. Salbreux, “Special rebranding
issue: ‘Quantitative cell and developmental biology,’” Cells and Development,
vol. 168, no. 12. Elsevier, 2021.'
ista: 'Heisenberg C-PJ, Lennon AM, Mayor R, Salbreux G. 2021. Special rebranding
issue: “Quantitative cell and developmental biology”. Cells and Development. 168(12),
203758.'
mla: 'Heisenberg, Carl-Philipp J., et al. “Special Rebranding Issue: ‘Quantitative
Cell and Developmental Biology.’” Cells and Development, vol. 168, no.
12, 203758, Elsevier, 2021, doi:10.1016/j.cdev.2021.203758.'
short: C.-P.J. Heisenberg, A.M. Lennon, R. Mayor, G. Salbreux, Cells and Development
168 (2021).
date_created: 2021-11-28T23:01:30Z
date_published: 2021-11-17T00:00:00Z
date_updated: 2023-08-14T13:02:40Z
day: '17'
department:
- _id: CaHe
doi: 10.1016/j.cdev.2021.203758
external_id:
isi:
- '000974771600028'
pmid:
- '34800748'
intvolume: ' 168'
isi: 1
issue: '12'
language:
- iso: eng
main_file_link:
- open_access: '1'
url: https://doi.org/10.1016/j.cdev.2021.203758
month: '11'
oa: 1
oa_version: Published Version
pmid: 1
publication: Cells and Development
publication_identifier:
issn:
- 2667-2901
publication_status: published
publisher: Elsevier
quality_controlled: '1'
scopus_import: '1'
status: public
title: 'Special rebranding issue: “Quantitative cell and developmental biology”'
type: journal_article
user_id: 4359f0d1-fa6c-11eb-b949-802e58b17ae8
volume: 168
year: '2021'
...
---
_id: '10406'
abstract:
- lang: eng
text: Multicellular organisms develop complex shapes from much simpler, single-celled
zygotes through a process commonly called morphogenesis. Morphogenesis involves
an interplay between several factors, ranging from the gene regulatory networks
determining cell fate and differentiation to the mechanical processes underlying
cell and tissue shape changes. Thus, the study of morphogenesis has historically
been based on multidisciplinary approaches at the interface of biology with physics
and mathematics. Recent technological advances have further improved our ability
to study morphogenesis by bridging the gap between the genetic and biophysical
factors through the development of new tools for visualizing, analyzing, and perturbing
these factors and their biochemical intermediaries. Here, we review how a combination
of genetic, microscopic, biophysical, and biochemical approaches has aided our
attempts to understand morphogenesis and discuss potential approaches that may
be beneficial to such an inquiry in the future.
acknowledgement: The authors would like to thank Feyza Nur Arslan, Suyash Naik, Diana
Pinheiro, Alexandra Schauer, and Shayan Shamipour for their comments on the draft.
N.M. is supported by an ISTplus postdoctoral fellowship (H2020 Marie-Sklodowska-Curie
COFUND Action).
article_processing_charge: No
article_type: original
author:
- first_name: Nikhil
full_name: Mishra, Nikhil
id: C4D70E82-1081-11EA-B3ED-9A4C3DDC885E
last_name: Mishra
orcid: 0000-0002-6425-5788
- first_name: Carl-Philipp J
full_name: Heisenberg, Carl-Philipp J
id: 39427864-F248-11E8-B48F-1D18A9856A87
last_name: Heisenberg
orcid: 0000-0002-0912-4566
citation:
ama: Mishra N, Heisenberg C-PJ. Dissecting organismal morphogenesis by bridging
genetics and biophysics. Annual Review of Genetics. 2021;55:209-233. doi:10.1146/annurev-genet-071819-103748
apa: Mishra, N., & Heisenberg, C.-P. J. (2021). Dissecting organismal morphogenesis
by bridging genetics and biophysics. Annual Review of Genetics. Annual
Reviews. https://doi.org/10.1146/annurev-genet-071819-103748
chicago: Mishra, Nikhil, and Carl-Philipp J Heisenberg. “Dissecting Organismal Morphogenesis
by Bridging Genetics and Biophysics.” Annual Review of Genetics. Annual
Reviews, 2021. https://doi.org/10.1146/annurev-genet-071819-103748.
ieee: N. Mishra and C.-P. J. Heisenberg, “Dissecting organismal morphogenesis by
bridging genetics and biophysics,” Annual Review of Genetics, vol. 55.
Annual Reviews, pp. 209–233, 2021.
ista: Mishra N, Heisenberg C-PJ. 2021. Dissecting organismal morphogenesis by bridging
genetics and biophysics. Annual Review of Genetics. 55, 209–233.
mla: Mishra, Nikhil, and Carl-Philipp J. Heisenberg. “Dissecting Organismal Morphogenesis
by Bridging Genetics and Biophysics.” Annual Review of Genetics, vol. 55,
Annual Reviews, 2021, pp. 209–33, doi:10.1146/annurev-genet-071819-103748.
short: N. Mishra, C.-P.J. Heisenberg, Annual Review of Genetics 55 (2021) 209–233.
date_created: 2021-12-05T23:01:41Z
date_published: 2021-08-30T00:00:00Z
date_updated: 2023-08-14T13:05:13Z
day: '30'
department:
- _id: CaHe
doi: 10.1146/annurev-genet-071819-103748
ec_funded: 1
external_id:
isi:
- '000747220900010'
pmid:
- '34460295'
intvolume: ' 55'
isi: 1
keyword:
- morphogenesis
- forward genetics
- high-resolution microscopy
- biophysics
- biochemistry
- patterning
language:
- iso: eng
month: '08'
oa_version: None
page: 209-233
pmid: 1
project:
- _id: 260C2330-B435-11E9-9278-68D0E5697425
call_identifier: H2020
grant_number: '754411'
name: ISTplus - Postdoctoral Fellowships
publication: Annual Review of Genetics
publication_identifier:
eissn:
- 1545-2948
issn:
- 0066-4197
publication_status: published
publisher: Annual Reviews
quality_controlled: '1'
scopus_import: '1'
status: public
title: Dissecting organismal morphogenesis by bridging genetics and biophysics
type: journal_article
user_id: 4359f0d1-fa6c-11eb-b949-802e58b17ae8
volume: 55
year: '2021'
...
---
_id: '10606'
abstract:
- lang: eng
text: Cell division orientation is thought to result from a competition between
cell geometry and polarity domains controlling the position of the mitotic spindle
during mitosis. Depending on the level of cell shape anisotropy or the strength
of the polarity domain, one dominates the other and determines the orientation
of the spindle. Whether and how such competition is also at work to determine
unequal cell division (UCD), producing daughter cells of different size, remains
unclear. Here, we show that cell geometry and polarity domains cooperate, rather
than compete, in positioning the cleavage plane during UCDs in early ascidian
embryos. We found that the UCDs and their orientation at the ascidian third cleavage
rely on the spindle tilting in an anisotropic cell shape, and cortical polarity
domains exerting different effects on spindle astral microtubules. By systematically
varying mitotic cell shape, we could modulate the effect of attractive and repulsive
polarity domains and consequently generate predicted daughter cell size asymmetries
and position. We therefore propose that the spindle position during UCD is set
by the combined activities of cell geometry and polarity domains, where cell geometry
modulates the effect of cortical polarity domain(s).
acknowledged_ssus:
- _id: NanoFab
- _id: Bio
acknowledgement: 'We thank members of the Heisenberg and McDougall groups for technical
advice and discussion. We are grateful to the Bioimaging and Nanofabrication facilities
of IST Austria and the Imaging Platform (PIM) and animal facility (CRB) of Institut
de la Mer de Villefranche (IMEV), which is supported by EMBRC-France, whose French
state funds are managed by the ANR within the Investments of the Future program
under reference ANR-10-INBS-0, for continuous support. This work was supported by
a collaborative grant from the French Government funding agency Agence National
de la Recherche to McDougall (ANR ''MorCell'': ANR-17-CE 13-0028) and the Austrian
Science Fund to Heisenberg (FWF: I 3601-B27).'
article_number: e75639
article_processing_charge: No
article_type: original
author:
- first_name: Benoit G
full_name: Godard, Benoit G
id: 33280250-F248-11E8-B48F-1D18A9856A87
last_name: Godard
- first_name: Remi
full_name: Dumollard, Remi
last_name: Dumollard
- first_name: Carl-Philipp J
full_name: Heisenberg, Carl-Philipp J
id: 39427864-F248-11E8-B48F-1D18A9856A87
last_name: Heisenberg
orcid: 0000-0002-0912-4566
- first_name: Alex
full_name: Mcdougall, Alex
last_name: Mcdougall
citation:
ama: Godard BG, Dumollard R, Heisenberg C-PJ, Mcdougall A. Combined effect of cell
geometry and polarity domains determines the orientation of unequal division.
eLife. 2021;10. doi:10.7554/eLife.75639
apa: Godard, B. G., Dumollard, R., Heisenberg, C.-P. J., & Mcdougall, A. (2021).
Combined effect of cell geometry and polarity domains determines the orientation
of unequal division. ELife. eLife Sciences Publications. https://doi.org/10.7554/eLife.75639
chicago: Godard, Benoit G, Remi Dumollard, Carl-Philipp J Heisenberg, and Alex Mcdougall.
“Combined Effect of Cell Geometry and Polarity Domains Determines the Orientation
of Unequal Division.” ELife. eLife Sciences Publications, 2021. https://doi.org/10.7554/eLife.75639.
ieee: B. G. Godard, R. Dumollard, C.-P. J. Heisenberg, and A. Mcdougall, “Combined
effect of cell geometry and polarity domains determines the orientation of unequal
division,” eLife, vol. 10. eLife Sciences Publications, 2021.
ista: Godard BG, Dumollard R, Heisenberg C-PJ, Mcdougall A. 2021. Combined effect
of cell geometry and polarity domains determines the orientation of unequal division.
eLife. 10, e75639.
mla: Godard, Benoit G., et al. “Combined Effect of Cell Geometry and Polarity Domains
Determines the Orientation of Unequal Division.” ELife, vol. 10, e75639,
eLife Sciences Publications, 2021, doi:10.7554/eLife.75639.
short: B.G. Godard, R. Dumollard, C.-P.J. Heisenberg, A. Mcdougall, ELife 10 (2021).
date_created: 2022-01-09T23:01:26Z
date_published: 2021-12-21T00:00:00Z
date_updated: 2023-08-17T06:32:44Z
day: '21'
ddc:
- '570'
department:
- _id: CaHe
doi: 10.7554/eLife.75639
external_id:
isi:
- '000733610100001'
file:
- access_level: open_access
checksum: 759c7a873d554c48a6639e6350746ca6
content_type: application/pdf
creator: alisjak
date_created: 2022-01-10T09:40:37Z
date_updated: 2022-01-10T09:40:37Z
file_id: '10611'
file_name: 2021_eLife_Godard.pdf
file_size: 7769934
relation: main_file
success: 1
file_date_updated: 2022-01-10T09:40:37Z
has_accepted_license: '1'
intvolume: ' 10'
isi: 1
language:
- iso: eng
month: '12'
oa: 1
oa_version: Published Version
project:
- _id: 2646861A-B435-11E9-9278-68D0E5697425
call_identifier: FWF
grant_number: I03601
name: Control of embryonic cleavage pattern
publication: eLife
publication_identifier:
eissn:
- 2050-084X
publication_status: published
publisher: eLife Sciences Publications
quality_controlled: '1'
scopus_import: '1'
status: public
title: Combined effect of cell geometry and polarity domains determines the orientation
of unequal division
tmp:
image: /images/cc_by.png
legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
short: CC BY (4.0)
type: journal_article
user_id: 4359f0d1-fa6c-11eb-b949-802e58b17ae8
volume: 10
year: '2021'
...
---
_id: '9298'
abstract:
- lang: eng
text: 'In 2008, we published the first set of guidelines for standardizing research
in autophagy. Since then, this topic has received increasing attention, and many
scientists have entered the field. Our knowledge base and relevant new technologies
have also been expanding. Thus, it is important to formulate on a regular basis
updated guidelines for monitoring autophagy in different organisms. Despite numerous
reviews, there continues to be confusion regarding acceptable methods to evaluate
autophagy, especially in multicellular eukaryotes. Here, we present a set of guidelines
for investigators to select and interpret methods to examine autophagy and related
processes, and for reviewers to provide realistic and reasonable critiques of
reports that are focused on these processes. These guidelines are not meant to
be a dogmatic set of rules, because the appropriateness of any assay largely depends
on the question being asked and the system being used. Moreover, no individual
assay is perfect for every situation, calling for the use of multiple techniques
to properly monitor autophagy in each experimental setting. Finally, several core
components of the autophagy machinery have been implicated in distinct autophagic
processes (canonical and noncanonical autophagy), implying that genetic approaches
to block autophagy should rely on targeting two or more autophagy-related genes
that ideally participate in distinct steps of the pathway. Along similar lines,
because multiple proteins involved in autophagy also regulate other cellular pathways
including apoptosis, not all of them can be used as a specific marker for bona
fide autophagic responses. Here, we critically discuss current methods of assessing
autophagy and the information they can, or cannot, provide. Our ultimate goal
is to encourage intellectual and technical innovation in the field. '
acknowledgement: This work was supported by the National Institute of General Medical
Sciences [GM131919]. Due to space and other limitations, it is not possible to include
all other sources of financial support.
article_processing_charge: No
article_type: review
author:
- first_name: Daniel J.
full_name: Klionsky, Daniel J.
last_name: Klionsky
- first_name: Amal Kamal
full_name: Abdel-Aziz, Amal Kamal
last_name: Abdel-Aziz
- first_name: Sara
full_name: Abdelfatah, Sara
last_name: Abdelfatah
- first_name: Mahmoud
full_name: Abdellatif, Mahmoud
last_name: Abdellatif
- first_name: Asghar
full_name: Abdoli, Asghar
last_name: Abdoli
- first_name: Steffen
full_name: Abel, Steffen
last_name: Abel
- first_name: Hagai
full_name: Abeliovich, Hagai
last_name: Abeliovich
- first_name: Marie H.
full_name: Abildgaard, Marie H.
last_name: Abildgaard
- first_name: Yakubu Princely
full_name: Abudu, Yakubu Princely
last_name: Abudu
- first_name: Abraham
full_name: Acevedo-Arozena, Abraham
last_name: Acevedo-Arozena
- first_name: Iannis E.
full_name: Adamopoulos, Iannis E.
last_name: Adamopoulos
- first_name: Khosrow
full_name: Adeli, Khosrow
last_name: Adeli
- first_name: Timon E.
full_name: Adolph, Timon E.
last_name: Adolph
- first_name: Annagrazia
full_name: Adornetto, Annagrazia
last_name: Adornetto
- first_name: Elma
full_name: Aflaki, Elma
last_name: Aflaki
- first_name: Galila
full_name: Agam, Galila
last_name: Agam
- first_name: Anupam
full_name: Agarwal, Anupam
last_name: Agarwal
- first_name: Bharat B.
full_name: Aggarwal, Bharat B.
last_name: Aggarwal
- first_name: Maria
full_name: Agnello, Maria
last_name: Agnello
- first_name: Patrizia
full_name: Agostinis, Patrizia
last_name: Agostinis
- first_name: Javed N.
full_name: Agrewala, Javed N.
last_name: Agrewala
- first_name: Alexander
full_name: Agrotis, Alexander
last_name: Agrotis
- first_name: Patricia V.
full_name: Aguilar, Patricia V.
last_name: Aguilar
- first_name: S. Tariq
full_name: Ahmad, S. Tariq
last_name: Ahmad
- first_name: Zubair M.
full_name: Ahmed, Zubair M.
last_name: Ahmed
- first_name: Ulises
full_name: Ahumada-Castro, Ulises
last_name: Ahumada-Castro
- first_name: Sonja
full_name: Aits, Sonja
last_name: Aits
- first_name: Shu
full_name: Aizawa, Shu
last_name: Aizawa
- first_name: Yunus
full_name: Akkoc, Yunus
last_name: Akkoc
- first_name: Tonia
full_name: Akoumianaki, Tonia
last_name: Akoumianaki
- first_name: Hafize Aysin
full_name: Akpinar, Hafize Aysin
last_name: Akpinar
- first_name: Ahmed M.
full_name: Al-Abd, Ahmed M.
last_name: Al-Abd
- first_name: Lina
full_name: Al-Akra, Lina
last_name: Al-Akra
- first_name: Abeer
full_name: Al-Gharaibeh, Abeer
last_name: Al-Gharaibeh
- first_name: Moulay A.
full_name: Alaoui-Jamali, Moulay A.
last_name: Alaoui-Jamali
- first_name: Simon
full_name: Alberti, Simon
last_name: Alberti
- first_name: Elísabet
full_name: Alcocer-Gómez, Elísabet
last_name: Alcocer-Gómez
- first_name: Cristiano
full_name: Alessandri, Cristiano
last_name: Alessandri
- first_name: Muhammad
full_name: Ali, Muhammad
last_name: Ali
- first_name: M. Abdul
full_name: Alim Al-Bari, M. Abdul
last_name: Alim Al-Bari
- first_name: Saeb
full_name: Aliwaini, Saeb
last_name: Aliwaini
- first_name: Javad
full_name: Alizadeh, Javad
last_name: Alizadeh
- first_name: Eugènia
full_name: Almacellas, Eugènia
last_name: Almacellas
- first_name: Alexandru
full_name: Almasan, Alexandru
last_name: Almasan
- first_name: Alicia
full_name: Alonso, Alicia
last_name: Alonso
- first_name: Guillermo D.
full_name: Alonso, Guillermo D.
last_name: Alonso
- first_name: Nihal
full_name: Altan-Bonnet, Nihal
last_name: Altan-Bonnet
- first_name: Dario C.
full_name: Altieri, Dario C.
last_name: Altieri
- first_name: Élida M.C.
full_name: Álvarez, Élida M.C.
last_name: Álvarez
- first_name: Sara
full_name: Alves, Sara
last_name: Alves
- first_name: Cristine
full_name: Alves Da Costa, Cristine
last_name: Alves Da Costa
- first_name: Mazen M.
full_name: Alzaharna, Mazen M.
last_name: Alzaharna
- first_name: Marialaura
full_name: Amadio, Marialaura
last_name: Amadio
- first_name: Consuelo
full_name: Amantini, Consuelo
last_name: Amantini
- first_name: Cristina
full_name: Amaral, Cristina
last_name: Amaral
- first_name: Susanna
full_name: Ambrosio, Susanna
last_name: Ambrosio
- first_name: Amal O.
full_name: Amer, Amal O.
last_name: Amer
- first_name: Veena
full_name: Ammanathan, Veena
last_name: Ammanathan
- first_name: Zhenyi
full_name: An, Zhenyi
last_name: An
- first_name: Stig U.
full_name: Andersen, Stig U.
last_name: Andersen
- first_name: Shaida A.
full_name: Andrabi, Shaida A.
last_name: Andrabi
- first_name: Magaiver
full_name: Andrade-Silva, Magaiver
last_name: Andrade-Silva
- first_name: Allen M.
full_name: Andres, Allen M.
last_name: Andres
- first_name: Sabrina
full_name: Angelini, Sabrina
last_name: Angelini
- first_name: David
full_name: Ann, David
last_name: Ann
- first_name: Uche C.
full_name: Anozie, Uche C.
last_name: Anozie
- first_name: Mohammad Y.
full_name: Ansari, Mohammad Y.
last_name: Ansari
- first_name: Pedro
full_name: Antas, Pedro
last_name: Antas
- first_name: Adam
full_name: Antebi, Adam
last_name: Antebi
- first_name: Zuriñe
full_name: Antón, Zuriñe
last_name: Antón
- first_name: Tahira
full_name: Anwar, Tahira
last_name: Anwar
- first_name: Lionel
full_name: Apetoh, Lionel
last_name: Apetoh
- first_name: Nadezda
full_name: Apostolova, Nadezda
last_name: Apostolova
- first_name: Toshiyuki
full_name: Araki, Toshiyuki
last_name: Araki
- first_name: Yasuhiro
full_name: Araki, Yasuhiro
last_name: Araki
- first_name: Kohei
full_name: Arasaki, Kohei
last_name: Arasaki
- first_name: Wagner L.
full_name: Araújo, Wagner L.
last_name: Araújo
- first_name: Jun
full_name: Araya, Jun
last_name: Araya
- first_name: Catherine
full_name: Arden, Catherine
last_name: Arden
- first_name: Maria Angeles
full_name: Arévalo, Maria Angeles
last_name: Arévalo
- first_name: Sandro
full_name: Arguelles, Sandro
last_name: Arguelles
- first_name: Esperanza
full_name: Arias, Esperanza
last_name: Arias
- first_name: Jyothi
full_name: Arikkath, Jyothi
last_name: Arikkath
- first_name: Hirokazu
full_name: Arimoto, Hirokazu
last_name: Arimoto
- first_name: Aileen R.
full_name: Ariosa, Aileen R.
last_name: Ariosa
- first_name: Darius
full_name: Armstrong-James, Darius
last_name: Armstrong-James
- first_name: Laetitia
full_name: Arnauné-Pelloquin, Laetitia
last_name: Arnauné-Pelloquin
- first_name: Angeles
full_name: Aroca, Angeles
last_name: Aroca
- first_name: Daniela S.
full_name: Arroyo, Daniela S.
last_name: Arroyo
- first_name: Ivica
full_name: Arsov, Ivica
last_name: Arsov
- first_name: Rubén
full_name: Artero, Rubén
last_name: Artero
- first_name: Dalia Maria Lucia
full_name: Asaro, Dalia Maria Lucia
last_name: Asaro
- first_name: Michael
full_name: Aschner, Michael
last_name: Aschner
- first_name: Milad
full_name: Ashrafizadeh, Milad
last_name: Ashrafizadeh
- first_name: Osnat
full_name: Ashur-Fabian, Osnat
last_name: Ashur-Fabian
- first_name: Atanas G.
full_name: Atanasov, Atanas G.
last_name: Atanasov
- first_name: Alicia K.
full_name: Au, Alicia K.
last_name: Au
- first_name: Patrick
full_name: Auberger, Patrick
last_name: Auberger
- first_name: Holger W.
full_name: Auner, Holger W.
last_name: Auner
- first_name: Laure
full_name: Aurelian, Laure
last_name: Aurelian
- first_name: Riccardo
full_name: Autelli, Riccardo
last_name: Autelli
- first_name: Laura
full_name: Avagliano, Laura
last_name: Avagliano
- first_name: Yenniffer
full_name: Ávalos, Yenniffer
last_name: Ávalos
- first_name: Sanja
full_name: Aveic, Sanja
last_name: Aveic
- first_name: Célia Alexandra
full_name: Aveleira, Célia Alexandra
last_name: Aveleira
- first_name: Tamar
full_name: Avin-Wittenberg, Tamar
last_name: Avin-Wittenberg
- first_name: Yucel
full_name: Aydin, Yucel
last_name: Aydin
- first_name: Scott
full_name: Ayton, Scott
last_name: Ayton
- first_name: Srinivas
full_name: Ayyadevara, Srinivas
last_name: Ayyadevara
- first_name: Maria
full_name: Azzopardi, Maria
last_name: Azzopardi
- first_name: Misuzu
full_name: Baba, Misuzu
last_name: Baba
- first_name: Jonathan M.
full_name: Backer, Jonathan M.
last_name: Backer
- first_name: Steven K.
full_name: Backues, Steven K.
last_name: Backues
- first_name: Dong Hun
full_name: Bae, Dong Hun
last_name: Bae
- first_name: Ok Nam
full_name: Bae, Ok Nam
last_name: Bae
- first_name: Soo Han
full_name: Bae, Soo Han
last_name: Bae
- first_name: Eric H.
full_name: Baehrecke, Eric H.
last_name: Baehrecke
- first_name: Ahruem
full_name: Baek, Ahruem
last_name: Baek
- first_name: Seung Hoon
full_name: Baek, Seung Hoon
last_name: Baek
- first_name: Sung Hee
full_name: Baek, Sung Hee
last_name: Baek
- first_name: Giacinto
full_name: Bagetta, Giacinto
last_name: Bagetta
- first_name: Agnieszka
full_name: Bagniewska-Zadworna, Agnieszka
last_name: Bagniewska-Zadworna
- first_name: Hua
full_name: Bai, Hua
last_name: Bai
- first_name: Jie
full_name: Bai, Jie
last_name: Bai
- first_name: Xiyuan
full_name: Bai, Xiyuan
last_name: Bai
- first_name: Yidong
full_name: Bai, Yidong
last_name: Bai
- first_name: Nandadulal
full_name: Bairagi, Nandadulal
last_name: Bairagi
- first_name: Shounak
full_name: Baksi, Shounak
last_name: Baksi
- first_name: Teresa
full_name: Balbi, Teresa
last_name: Balbi
- first_name: Cosima T.
full_name: Baldari, Cosima T.
last_name: Baldari
- first_name: Walter
full_name: Balduini, Walter
last_name: Balduini
- first_name: Andrea
full_name: Ballabio, Andrea
last_name: Ballabio
- first_name: Maria
full_name: Ballester, Maria
last_name: Ballester
- first_name: Salma
full_name: Balazadeh, Salma
last_name: Balazadeh
- first_name: Rena
full_name: Balzan, Rena
last_name: Balzan
- first_name: Rina
full_name: Bandopadhyay, Rina
last_name: Bandopadhyay
- first_name: Sreeparna
full_name: Banerjee, Sreeparna
last_name: Banerjee
- first_name: Sulagna
full_name: Banerjee, Sulagna
last_name: Banerjee
- first_name: Ágnes
full_name: Bánréti, Ágnes
last_name: Bánréti
- first_name: Yan
full_name: Bao, Yan
last_name: Bao
- first_name: Mauricio S.
full_name: Baptista, Mauricio S.
last_name: Baptista
- first_name: Alessandra
full_name: Baracca, Alessandra
last_name: Baracca
- first_name: Cristiana
full_name: Barbati, Cristiana
last_name: Barbati
- first_name: Ariadna
full_name: Bargiela, Ariadna
last_name: Bargiela
- first_name: Daniela
full_name: Barilà, Daniela
last_name: Barilà
- first_name: Peter G.
full_name: Barlow, Peter G.
last_name: Barlow
- first_name: Sami J.
full_name: Barmada, Sami J.
last_name: Barmada
- first_name: Esther
full_name: Barreiro, Esther
last_name: Barreiro
- first_name: George E.
full_name: Barreto, George E.
last_name: Barreto
- first_name: Jiri
full_name: Bartek, Jiri
last_name: Bartek
- first_name: Bonnie
full_name: Bartel, Bonnie
last_name: Bartel
- first_name: Alberto
full_name: Bartolome, Alberto
last_name: Bartolome
- first_name: Gaurav R.
full_name: Barve, Gaurav R.
last_name: Barve
- first_name: Suresh H.
full_name: Basagoudanavar, Suresh H.
last_name: Basagoudanavar
- first_name: Diane C.
full_name: Bassham, Diane C.
last_name: Bassham
- first_name: Robert C.
full_name: Bast, Robert C.
last_name: Bast
- first_name: Alakananda
full_name: Basu, Alakananda
last_name: Basu
- first_name: Henri
full_name: Batoko, Henri
last_name: Batoko
- first_name: Isabella
full_name: Batten, Isabella
last_name: Batten
- first_name: Etienne E.
full_name: Baulieu, Etienne E.
last_name: Baulieu
- first_name: Bradley L.
full_name: Baumgarner, Bradley L.
last_name: Baumgarner
- first_name: Jagadeesh
full_name: Bayry, Jagadeesh
last_name: Bayry
- first_name: Rupert
full_name: Beale, Rupert
last_name: Beale
- first_name: Isabelle
full_name: Beau, Isabelle
last_name: Beau
- first_name: Florian
full_name: Beaumatin, Florian
last_name: Beaumatin
- first_name: Luiz R.G.
full_name: Bechara, Luiz R.G.
last_name: Bechara
- first_name: George R.
full_name: Beck, George R.
last_name: Beck
- first_name: Michael F.
full_name: Beers, Michael F.
last_name: Beers
- first_name: Jakob
full_name: Begun, Jakob
last_name: Begun
- first_name: Christian
full_name: Behrends, Christian
last_name: Behrends
- first_name: Georg M.N.
full_name: Behrens, Georg M.N.
last_name: Behrens
- first_name: Roberto
full_name: Bei, Roberto
last_name: Bei
- first_name: Eloy
full_name: Bejarano, Eloy
last_name: Bejarano
- first_name: Shai
full_name: Bel, Shai
last_name: Bel
- first_name: Christian
full_name: Behl, Christian
last_name: Behl
- first_name: Amine
full_name: Belaid, Amine
last_name: Belaid
- first_name: Naïma
full_name: Belgareh-Touzé, Naïma
last_name: Belgareh-Touzé
- first_name: Cristina
full_name: Bellarosa, Cristina
last_name: Bellarosa
- first_name: Francesca
full_name: Belleudi, Francesca
last_name: Belleudi
- first_name: Melissa
full_name: Belló Pérez, Melissa
last_name: Belló Pérez
- first_name: Raquel
full_name: Bello-Morales, Raquel
last_name: Bello-Morales
- first_name: Jackeline Soares De Oliveira
full_name: Beltran, Jackeline Soares De Oliveira
last_name: Beltran
- first_name: Sebastián
full_name: Beltran, Sebastián
last_name: Beltran
- first_name: Doris Mangiaracina
full_name: Benbrook, Doris Mangiaracina
last_name: Benbrook
- first_name: Mykolas
full_name: Bendorius, Mykolas
last_name: Bendorius
- first_name: Bruno A.
full_name: Benitez, Bruno A.
last_name: Benitez
- first_name: Irene
full_name: Benito-Cuesta, Irene
last_name: Benito-Cuesta
- first_name: Julien
full_name: Bensalem, Julien
last_name: Bensalem
- first_name: Martin W.
full_name: Berchtold, Martin W.
last_name: Berchtold
- first_name: Sabina
full_name: Berezowska, Sabina
last_name: Berezowska
- first_name: Daniele
full_name: Bergamaschi, Daniele
last_name: Bergamaschi
- first_name: Matteo
full_name: Bergami, Matteo
last_name: Bergami
- first_name: Andreas
full_name: Bergmann, Andreas
last_name: Bergmann
- first_name: Laura
full_name: Berliocchi, Laura
last_name: Berliocchi
- first_name: Clarisse
full_name: Berlioz-Torrent, Clarisse
last_name: Berlioz-Torrent
- first_name: Amélie
full_name: Bernard, Amélie
last_name: Bernard
- first_name: Lionel
full_name: Berthoux, Lionel
last_name: Berthoux
- first_name: Cagri G.
full_name: Besirli, Cagri G.
last_name: Besirli
- first_name: Sebastien
full_name: Besteiro, Sebastien
last_name: Besteiro
- first_name: Virginie M.
full_name: Betin, Virginie M.
last_name: Betin
- first_name: Rudi
full_name: Beyaert, Rudi
last_name: Beyaert
- first_name: Jelena S.
full_name: Bezbradica, Jelena S.
last_name: Bezbradica
- first_name: Kiran
full_name: Bhaskar, Kiran
last_name: Bhaskar
- first_name: Ingrid
full_name: Bhatia-Kissova, Ingrid
last_name: Bhatia-Kissova
- first_name: Resham
full_name: Bhattacharya, Resham
last_name: Bhattacharya
- first_name: Sujoy
full_name: Bhattacharya, Sujoy
last_name: Bhattacharya
- first_name: Shalmoli
full_name: Bhattacharyya, Shalmoli
last_name: Bhattacharyya
- first_name: Md Shenuarin
full_name: Bhuiyan, Md Shenuarin
last_name: Bhuiyan
- first_name: Sujit Kumar
full_name: Bhutia, Sujit Kumar
last_name: Bhutia
- first_name: Lanrong
full_name: Bi, Lanrong
last_name: Bi
- first_name: Xiaolin
full_name: Bi, Xiaolin
last_name: Bi
- first_name: Trevor J.
full_name: Biden, Trevor J.
last_name: Biden
- first_name: Krikor
full_name: Bijian, Krikor
last_name: Bijian
- first_name: Viktor A.
full_name: Billes, Viktor A.
last_name: Billes
- first_name: Nadine
full_name: Binart, Nadine
last_name: Binart
- first_name: Claudia
full_name: Bincoletto, Claudia
last_name: Bincoletto
- first_name: Asa B.
full_name: Birgisdottir, Asa B.
last_name: Birgisdottir
- first_name: Geir
full_name: Bjorkoy, Geir
last_name: Bjorkoy
- first_name: Gonzalo
full_name: Blanco, Gonzalo
last_name: Blanco
- first_name: Ana
full_name: Blas-Garcia, Ana
last_name: Blas-Garcia
- first_name: Janusz
full_name: Blasiak, Janusz
last_name: Blasiak
- first_name: Robert
full_name: Blomgran, Robert
last_name: Blomgran
- first_name: Klas
full_name: Blomgren, Klas
last_name: Blomgren
- first_name: Janice S.
full_name: Blum, Janice S.
last_name: Blum
- first_name: Emilio
full_name: Boada-Romero, Emilio
last_name: Boada-Romero
- first_name: Mirta
full_name: Boban, Mirta
last_name: Boban
- first_name: Kathleen
full_name: Boesze-Battaglia, Kathleen
last_name: Boesze-Battaglia
- first_name: Philippe
full_name: Boeuf, Philippe
last_name: Boeuf
- first_name: Barry
full_name: Boland, Barry
last_name: Boland
- first_name: Pascale
full_name: Bomont, Pascale
last_name: Bomont
- first_name: Paolo
full_name: Bonaldo, Paolo
last_name: Bonaldo
- first_name: Srinivasa Reddy
full_name: Bonam, Srinivasa Reddy
last_name: Bonam
- first_name: Laura
full_name: Bonfili, Laura
last_name: Bonfili
- first_name: Juan S.
full_name: Bonifacino, Juan S.
last_name: Bonifacino
- first_name: Brian A.
full_name: Boone, Brian A.
last_name: Boone
- first_name: Martin D.
full_name: Bootman, Martin D.
last_name: Bootman
- first_name: Matteo
full_name: Bordi, Matteo
last_name: Bordi
- first_name: Christoph
full_name: Borner, Christoph
last_name: Borner
- first_name: Beat C.
full_name: Bornhauser, Beat C.
last_name: Bornhauser
- first_name: Gautam
full_name: Borthakur, Gautam
last_name: Borthakur
- first_name: Jürgen
full_name: Bosch, Jürgen
last_name: Bosch
- first_name: Santanu
full_name: Bose, Santanu
last_name: Bose
- first_name: Luis M.
full_name: Botana, Luis M.
last_name: Botana
- first_name: Juan
full_name: Botas, Juan
last_name: Botas
- first_name: Chantal M.
full_name: Boulanger, Chantal M.
last_name: Boulanger
- first_name: Michael E.
full_name: Boulton, Michael E.
last_name: Boulton
- first_name: Mathieu
full_name: Bourdenx, Mathieu
last_name: Bourdenx
- first_name: Benjamin
full_name: Bourgeois, Benjamin
last_name: Bourgeois
- first_name: Nollaig M.
full_name: Bourke, Nollaig M.
last_name: Bourke
- first_name: Guilhem
full_name: Bousquet, Guilhem
last_name: Bousquet
- first_name: Patricia
full_name: Boya, Patricia
last_name: Boya
- first_name: Peter V.
full_name: Bozhkov, Peter V.
last_name: Bozhkov
- first_name: Luiz H.M.
full_name: Bozi, Luiz H.M.
last_name: Bozi
- first_name: Tolga O.
full_name: Bozkurt, Tolga O.
last_name: Bozkurt
- first_name: Doug E.
full_name: Brackney, Doug E.
last_name: Brackney
- first_name: Christian H.
full_name: Brandts, Christian H.
last_name: Brandts
- first_name: Ralf J.
full_name: Braun, Ralf J.
last_name: Braun
- first_name: Gerhard H.
full_name: Braus, Gerhard H.
last_name: Braus
- first_name: Roberto
full_name: Bravo-Sagua, Roberto
last_name: Bravo-Sagua
- first_name: José M.
full_name: Bravo-San Pedro, José M.
last_name: Bravo-San Pedro
- first_name: Patrick
full_name: Brest, Patrick
last_name: Brest
- first_name: Marie Agnès
full_name: Bringer, Marie Agnès
last_name: Bringer
- first_name: Alfredo
full_name: Briones-Herrera, Alfredo
last_name: Briones-Herrera
- first_name: V. Courtney
full_name: Broaddus, V. Courtney
last_name: Broaddus
- first_name: Peter
full_name: Brodersen, Peter
last_name: Brodersen
- first_name: Jeffrey L.
full_name: Brodsky, Jeffrey L.
last_name: Brodsky
- first_name: Steven L.
full_name: Brody, Steven L.
last_name: Brody
- first_name: Paola G.
full_name: Bronson, Paola G.
last_name: Bronson
- first_name: Jeff M.
full_name: Bronstein, Jeff M.
last_name: Bronstein
- first_name: Carolyn N.
full_name: Brown, Carolyn N.
last_name: Brown
- first_name: Rhoderick E.
full_name: Brown, Rhoderick E.
last_name: Brown
- first_name: Patricia C.
full_name: Brum, Patricia C.
last_name: Brum
- first_name: John H.
full_name: Brumell, John H.
last_name: Brumell
- first_name: Nicola
full_name: Brunetti-Pierri, Nicola
last_name: Brunetti-Pierri
- first_name: Daniele
full_name: Bruno, Daniele
last_name: Bruno
- first_name: Robert J.
full_name: Bryson-Richardson, Robert J.
last_name: Bryson-Richardson
- first_name: Cecilia
full_name: Bucci, Cecilia
last_name: Bucci
- first_name: Carmen
full_name: Buchrieser, Carmen
last_name: Buchrieser
- first_name: Marta
full_name: Bueno, Marta
last_name: Bueno
- first_name: Laura Elisa
full_name: Buitrago-Molina, Laura Elisa
last_name: Buitrago-Molina
- first_name: Simone
full_name: Buraschi, Simone
last_name: Buraschi
- first_name: Shilpa
full_name: Buch, Shilpa
last_name: Buch
- first_name: J. Ross
full_name: Buchan, J. Ross
last_name: Buchan
- first_name: Erin M.
full_name: Buckingham, Erin M.
last_name: Buckingham
- first_name: Hikmet
full_name: Budak, Hikmet
last_name: Budak
- first_name: Mauricio
full_name: Budini, Mauricio
last_name: Budini
- first_name: Geert
full_name: Bultynck, Geert
last_name: Bultynck
- first_name: Florin
full_name: Burada, Florin
last_name: Burada
- first_name: Joseph R.
full_name: Burgoyne, Joseph R.
last_name: Burgoyne
- first_name: M. Isabel
full_name: Burón, M. Isabel
last_name: Burón
- first_name: Victor
full_name: Bustos, Victor
last_name: Bustos
- first_name: Sabrina
full_name: Büttner, Sabrina
last_name: Büttner
- first_name: Elena
full_name: Butturini, Elena
last_name: Butturini
- first_name: Aaron
full_name: Byrd, Aaron
last_name: Byrd
- first_name: Isabel
full_name: Cabas, Isabel
last_name: Cabas
- first_name: Sandra
full_name: Cabrera-Benitez, Sandra
last_name: Cabrera-Benitez
- first_name: Ken
full_name: Cadwell, Ken
last_name: Cadwell
- first_name: Jingjing
full_name: Cai, Jingjing
last_name: Cai
- first_name: Lu
full_name: Cai, Lu
last_name: Cai
- first_name: Qian
full_name: Cai, Qian
last_name: Cai
- first_name: Montserrat
full_name: Cairó, Montserrat
last_name: Cairó
- first_name: Jose A.
full_name: Calbet, Jose A.
last_name: Calbet
- first_name: Guy A.
full_name: Caldwell, Guy A.
last_name: Caldwell
- first_name: Kim A.
full_name: Caldwell, Kim A.
last_name: Caldwell
- first_name: Jarrod A.
full_name: Call, Jarrod A.
last_name: Call
- first_name: Riccardo
full_name: Calvani, Riccardo
last_name: Calvani
- first_name: Ana C.
full_name: Calvo, Ana C.
last_name: Calvo
- first_name: Miguel
full_name: Calvo-Rubio Barrera, Miguel
last_name: Calvo-Rubio Barrera
- first_name: Niels O.S.
full_name: Camara, Niels O.S.
last_name: Camara
- first_name: Jacques H.
full_name: Camonis, Jacques H.
last_name: Camonis
- first_name: Nadine
full_name: Camougrand, Nadine
last_name: Camougrand
- first_name: Michelangelo
full_name: Campanella, Michelangelo
last_name: Campanella
- first_name: Edward M.
full_name: Campbell, Edward M.
last_name: Campbell
- first_name: François Xavier
full_name: Campbell-Valois, François Xavier
last_name: Campbell-Valois
- first_name: Silvia
full_name: Campello, Silvia
last_name: Campello
- first_name: Ilaria
full_name: Campesi, Ilaria
last_name: Campesi
- first_name: Juliane C.
full_name: Campos, Juliane C.
last_name: Campos
- first_name: Olivier
full_name: Camuzard, Olivier
last_name: Camuzard
- first_name: Jorge
full_name: Cancino, Jorge
last_name: Cancino
- first_name: Danilo
full_name: Candido De Almeida, Danilo
last_name: Candido De Almeida
- first_name: Laura
full_name: Canesi, Laura
last_name: Canesi
- first_name: Isabella
full_name: Caniggia, Isabella
last_name: Caniggia
- first_name: Barbara
full_name: Canonico, Barbara
last_name: Canonico
- first_name: Carles
full_name: Cantí, Carles
last_name: Cantí
- first_name: Bin
full_name: Cao, Bin
last_name: Cao
- first_name: Michele
full_name: Caraglia, Michele
last_name: Caraglia
- first_name: Beatriz
full_name: Caramés, Beatriz
last_name: Caramés
- first_name: Evie H.
full_name: Carchman, Evie H.
last_name: Carchman
- first_name: Elena
full_name: Cardenal-Muñoz, Elena
last_name: Cardenal-Muñoz
- first_name: Cesar
full_name: Cardenas, Cesar
last_name: Cardenas
- first_name: Luis
full_name: Cardenas, Luis
last_name: Cardenas
- first_name: Sandra M.
full_name: Cardoso, Sandra M.
last_name: Cardoso
- first_name: Jennifer S.
full_name: Carew, Jennifer S.
last_name: Carew
- first_name: Georges F.
full_name: Carle, Georges F.
last_name: Carle
- first_name: Gillian
full_name: Carleton, Gillian
last_name: Carleton
- first_name: Silvia
full_name: Carloni, Silvia
last_name: Carloni
- first_name: Didac
full_name: Carmona-Gutierrez, Didac
last_name: Carmona-Gutierrez
- first_name: Leticia A.
full_name: Carneiro, Leticia A.
last_name: Carneiro
- first_name: Oliana
full_name: Carnevali, Oliana
last_name: Carnevali
- first_name: Julian M.
full_name: Carosi, Julian M.
last_name: Carosi
- first_name: Serena
full_name: Carra, Serena
last_name: Carra
- first_name: Alice
full_name: Carrier, Alice
last_name: Carrier
- first_name: Lucie
full_name: Carrier, Lucie
last_name: Carrier
- first_name: Bernadette
full_name: Carroll, Bernadette
last_name: Carroll
- first_name: A. Brent
full_name: Carter, A. Brent
last_name: Carter
- first_name: Andreia Neves
full_name: Carvalho, Andreia Neves
last_name: Carvalho
- first_name: Magali
full_name: Casanova, Magali
last_name: Casanova
- first_name: Caty
full_name: Casas, Caty
last_name: Casas
- first_name: Josefina
full_name: Casas, Josefina
last_name: Casas
- first_name: Chiara
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- first_name: Eliseo F.
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- first_name: Karen
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- first_name: Sonia
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- first_name: Francesca
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- first_name: Marco
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- first_name: Ariel F.
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- first_name: Margarida
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- first_name: Javier
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- first_name: Susana
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- first_name: Sergio D.
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- first_name: Claudia
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- first_name: Federica
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- first_name: Gabriella
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- first_name: Maria
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- first_name: Maria L.
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- first_name: Paula
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- first_name: Valentina
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- first_name: Francesco
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- first_name: Marzanna
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- first_name: Simone
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- first_name: Victòria
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- first_name: João J.
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last_name: Cerqueira
- first_name: Janete M.
full_name: Cerutti, Janete M.
last_name: Cerutti
- first_name: Davide
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last_name: Cervia
- first_name: Vildan Bozok
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- first_name: Silvia
full_name: Cetrullo, Silvia
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- first_name: Han Jung
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- first_name: Andrei S.
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- first_name: Chee Yin
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- first_name: Gopal
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- first_name: Oishee
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- first_name: Tapas
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- first_name: Trinad
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- first_name: Mounia
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- first_name: Georgios
full_name: Chamilos, Georgios
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- first_name: David W.
full_name: Chan, David W.
last_name: Chan
- first_name: Edmond Y.W.
full_name: Chan, Edmond Y.W.
last_name: Chan
- first_name: Edward D.
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- first_name: H. Y.Edwin
full_name: Chan, H. Y.Edwin
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- first_name: Helen H.
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- first_name: Hung
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- first_name: Matthew T.V.
full_name: Chan, Matthew T.V.
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- first_name: Yau Sang
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last_name: Chan
- first_name: Partha K.
full_name: Chandra, Partha K.
last_name: Chandra
- first_name: Chih Peng
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- first_name: Chunmei
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- first_name: Hao Chun
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- first_name: Kai
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- first_name: Jie
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- first_name: Tracey
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- first_name: Nicolas
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- first_name: Samrat
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- first_name: Shail K.
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- first_name: Anu
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- first_name: Santosh
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- first_name: Edward
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- first_name: Frédéric
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- first_name: Michael E.
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- first_name: Chang Shi
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- first_name: Guang Chao
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- first_name: Jian Fu
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- first_name: Liam L.
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- first_name: Leilei
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- first_name: Lin
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- first_name: Mingliang
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- first_name: Mu Kuan
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- first_name: Ning
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- first_name: Quan
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- first_name: Ruey Hwa
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- first_name: Shi
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- first_name: Wei
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- first_name: Weiqiang
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- first_name: Xin Ming
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- first_name: Xiong Wen
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- first_name: Xu
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- first_name: Yan
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- first_name: Ye Guang
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- first_name: Yingyu
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- first_name: Yongqiang
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- first_name: Yu Jen
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- first_name: Yue Qin
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- first_name: Zhefan Stephen
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- first_name: Zhi
full_name: Chen, Zhi
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- first_name: Zhi Hua
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- first_name: Zhijian J.
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- first_name: Zhixiang
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- first_name: Hanhua
full_name: Cheng, Hanhua
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- first_name: Jun
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- first_name: Shi Yuan
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- first_name: Wei
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- first_name: Xiaodong
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- first_name: Xiu Tang
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- first_name: Yiyun
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- first_name: Zhiyong
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- first_name: Zhong
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- first_name: Heesun
full_name: Cheong, Heesun
last_name: Cheong
- first_name: Jit Kong
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last_name: Cheong
- first_name: Boris V.
full_name: Chernyak, Boris V.
last_name: Chernyak
- first_name: Sara
full_name: Cherry, Sara
last_name: Cherry
- first_name: Chi Fai Randy
full_name: Cheung, Chi Fai Randy
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- first_name: Chun Hei Antonio
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- first_name: King Ho
full_name: Cheung, King Ho
last_name: Cheung
- first_name: Eric
full_name: Chevet, Eric
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- first_name: Richard J.
full_name: Chi, Richard J.
last_name: Chi
- first_name: Alan Kwok Shing
full_name: Chiang, Alan Kwok Shing
last_name: Chiang
- first_name: Ferdinando
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- first_name: Roberto
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- first_name: Mario
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- first_name: Nathalia
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- first_name: Susanna
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- first_name: Mario
full_name: Chiong, Mario
last_name: Chiong
- first_name: Shih Hwa
full_name: Chiou, Shih Hwa
last_name: Chiou
- first_name: Abhilash I.
full_name: Chiramel, Abhilash I.
last_name: Chiramel
- first_name: Valerio
full_name: Chiurchiù, Valerio
last_name: Chiurchiù
- first_name: Dong Hyung
full_name: Cho, Dong Hyung
last_name: Cho
- first_name: Seong Kyu
full_name: Choe, Seong Kyu
last_name: Choe
- first_name: Augustine M.K.
full_name: Choi, Augustine M.K.
last_name: Choi
- first_name: Mary E.
full_name: Choi, Mary E.
last_name: Choi
- first_name: Kamalika Roy
full_name: Choudhury, Kamalika Roy
last_name: Choudhury
- first_name: Norman S.
full_name: Chow, Norman S.
last_name: Chow
- first_name: Charleen T.
full_name: Chu, Charleen T.
last_name: Chu
- first_name: Jason P.
full_name: Chua, Jason P.
last_name: Chua
- first_name: John Jia En
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last_name: Chua
- first_name: Hyewon
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- first_name: Kin Pan
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- first_name: Seockhoon
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- first_name: So Hyang
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- first_name: Yuen Li
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- first_name: Valentina
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- first_name: Iwona A.
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last_name: Ciechomska
- first_name: Mariana
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- first_name: Laura
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- first_name: Sebahattin
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- first_name: Mara
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- first_name: Michael J.
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- first_name: Robert
full_name: Clarke, Robert
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- first_name: Emilio
full_name: Clementi, Emilio
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- first_name: Eliana M.
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- first_name: Patrice
full_name: Codogno, Patrice
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- first_name: Ehud
full_name: Cohen, Ehud
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- first_name: Mickael M.
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- first_name: Tania
full_name: Colasanti, Tania
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- first_name: Fiorella
full_name: Colasuonno, Fiorella
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- first_name: Robert A.
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last_name: Colbert
- first_name: Anna
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- first_name: Miodrag
full_name: Čolić, Miodrag
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- first_name: Nuria S.
full_name: Coll, Nuria S.
last_name: Coll
- first_name: Mark O.
full_name: Collins, Mark O.
last_name: Collins
- first_name: María I.
full_name: Colombo, María I.
last_name: Colombo
- first_name: Daniel A.
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last_name: Colón-Ramos
- first_name: Lydie
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- first_name: Sergio
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- first_name: Márcia R.
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- first_name: Antonella
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- first_name: Andrea
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- first_name: Fabrizio
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- first_name: Viorica Raluca
full_name: Contu, Viorica Raluca
last_name: Contu
- first_name: Mark R.
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last_name: Cookson
- first_name: Kevin M.
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- first_name: Isabelle
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last_name: Coppens
- first_name: Maria Tiziana
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- first_name: Dale P.
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- first_name: Nils
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- first_name: Katia
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- first_name: Ana
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- first_name: Peter J.
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- first_name: Jose L.
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- first_name: Alfredo
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- first_name: Valeria
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- first_name: Yong
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- first_name: Emmanuel
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last_name: Culetto
- first_name: Andrea C.
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last_name: Cumino
- first_name: Andrey V.
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last_name: Cybulsky
- first_name: Mark J.
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last_name: Czaja
- first_name: Stanislaw J.
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- first_name: Stefania
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- first_name: Daniela
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- first_name: Andrew C.
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last_name: D’Lugos
- first_name: Gabriella
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last_name: D’Orazi
- first_name: James A.
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last_name: Da Silva
- first_name: Hormos Salimi
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last_name: Dafsari
- first_name: Ruben K.
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- first_name: Yasin
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- first_name: Maria
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- first_name: Xiaoxia
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- first_name: Jessica
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- first_name: Markus
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- first_name: Ilaria
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- first_name: Nico P.
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last_name: Dantuma
- first_name: April L.
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last_name: Darling
- first_name: Hiranmoy
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- first_name: Srinivasan
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- first_name: Santosh K.
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- first_name: Srikanta
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last_name: Dash
- first_name: Oliver
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last_name: Daumke
- first_name: Adrian N.
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- first_name: Jeffrey S.
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last_name: Davies
- first_name: Valeria A.
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last_name: Dávila
- first_name: Roger J.
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- first_name: Tanja
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- first_name: Sharadha
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- first_name: Chiara
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- first_name: Mayara G.
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- first_name: Guido R.Y.
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last_name: De Meyer
- first_name: Angelo
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- first_name: Cosimo
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- first_name: Clara
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- first_name: Mauro
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- first_name: Claudio
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- first_name: Daniela
full_name: De Zio, Daniela
last_name: De Zio
- first_name: Jayanta
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last_name: Debnath
- first_name: Brian J.
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last_name: Debosch
- first_name: Jean Paul
full_name: Decuypere, Jean Paul
last_name: Decuypere
- first_name: Mark A.
full_name: Deehan, Mark A.
last_name: Deehan
- first_name: Gianluca
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- first_name: James
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- first_name: Benjamin
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last_name: Dehay
- first_name: Gabriel
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last_name: Del Rio
- first_name: Joe R.
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last_name: Delaney
- first_name: Lea M.D.
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last_name: Delbridge
- first_name: Elizabeth
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- first_name: M. Victoria
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- first_name: Francesca
full_name: Demarchi, Francesca
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- first_name: Vilma
full_name: Dembitz, Vilma
last_name: Dembitz
- first_name: Nicholas D.
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last_name: Demers
- first_name: Hongbin
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last_name: Deng
- first_name: Zhiqiang
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- first_name: Paul
full_name: Dent, Paul
last_name: Dent
- first_name: Donna
full_name: Denton, Donna
last_name: Denton
- first_name: Melvin L.
full_name: Depamphilis, Melvin L.
last_name: Depamphilis
- first_name: Channing J.
full_name: Der, Channing J.
last_name: Der
- first_name: Vojo
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last_name: Deretic
- first_name: Albert
full_name: Descoteaux, Albert
last_name: Descoteaux
- first_name: Laura
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- first_name: Sushil
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- first_name: Olivier
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- first_name: Grant
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- first_name: Mahendiran
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- first_name: Rohan
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- first_name: Diego
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- first_name: Manlio
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- first_name: Fabio
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- first_name: Pietro
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- first_name: Alessio
full_name: Di Fonzo, Alessio
last_name: Di Fonzo
- first_name: Giovanni
full_name: Di Guardo, Giovanni
last_name: Di Guardo
- first_name: Gianni M.
full_name: Di Guglielmo, Gianni M.
last_name: Di Guglielmo
- first_name: Luca
full_name: Di Leo, Luca
last_name: Di Leo
- first_name: Chiara
full_name: Di Malta, Chiara
last_name: Di Malta
- first_name: Alessia
full_name: Di Nardo, Alessia
last_name: Di Nardo
- first_name: Martina
full_name: Di Rienzo, Martina
last_name: Di Rienzo
- first_name: Federica
full_name: Di Sano, Federica
last_name: Di Sano
- first_name: George
full_name: Diallinas, George
last_name: Diallinas
- first_name: Jiajie
full_name: Diao, Jiajie
last_name: Diao
- first_name: Guillermo
full_name: Diaz-Araya, Guillermo
last_name: Diaz-Araya
- first_name: Inés
full_name: Díaz-Laviada, Inés
last_name: Díaz-Laviada
- first_name: Jared M.
full_name: Dickinson, Jared M.
last_name: Dickinson
- first_name: Marc
full_name: Diederich, Marc
last_name: Diederich
- first_name: Mélanie
full_name: Dieudé, Mélanie
last_name: Dieudé
- first_name: Ivan
full_name: Dikic, Ivan
last_name: Dikic
- first_name: Shiping
full_name: Ding, Shiping
last_name: Ding
- first_name: Wen Xing
full_name: Ding, Wen Xing
last_name: Ding
- first_name: Luciana
full_name: Dini, Luciana
last_name: Dini
- first_name: Jelena
full_name: Dinić, Jelena
last_name: Dinić
- first_name: Miroslav
full_name: Dinic, Miroslav
last_name: Dinic
- first_name: Albena T.
full_name: Dinkova-Kostova, Albena T.
last_name: Dinkova-Kostova
- first_name: Marc S.
full_name: Dionne, Marc S.
last_name: Dionne
- first_name: Jörg H.W.
full_name: Distler, Jörg H.W.
last_name: Distler
- first_name: Abhinav
full_name: Diwan, Abhinav
last_name: Diwan
- first_name: Ian M.C.
full_name: Dixon, Ian M.C.
last_name: Dixon
- first_name: Mojgan
full_name: Djavaheri-Mergny, Mojgan
last_name: Djavaheri-Mergny
- first_name: Ina
full_name: Dobrinski, Ina
last_name: Dobrinski
- first_name: Oxana
full_name: Dobrovinskaya, Oxana
last_name: Dobrovinskaya
- first_name: Radek
full_name: Dobrowolski, Radek
last_name: Dobrowolski
- first_name: Renwick C.J.
full_name: Dobson, Renwick C.J.
last_name: Dobson
- first_name: Jelena
full_name: Đokić, Jelena
last_name: Đokić
- first_name: Serap
full_name: Dokmeci Emre, Serap
last_name: Dokmeci Emre
- first_name: Massimo
full_name: Donadelli, Massimo
last_name: Donadelli
- first_name: Bo
full_name: Dong, Bo
last_name: Dong
- first_name: Xiaonan
full_name: Dong, Xiaonan
last_name: Dong
- first_name: Zhiwu
full_name: Dong, Zhiwu
last_name: Dong
- first_name: Gerald W.
full_name: Dorn, Gerald W.
last_name: Dorn
- first_name: Volker
full_name: Dotsch, Volker
last_name: Dotsch
- first_name: Huan
full_name: Dou, Huan
last_name: Dou
- first_name: Juan
full_name: Dou, Juan
last_name: Dou
- first_name: Moataz
full_name: Dowaidar, Moataz
last_name: Dowaidar
- first_name: Sami
full_name: Dridi, Sami
last_name: Dridi
- first_name: Liat
full_name: Drucker, Liat
last_name: Drucker
- first_name: Ailian
full_name: Du, Ailian
last_name: Du
- first_name: Caigan
full_name: Du, Caigan
last_name: Du
- first_name: Guangwei
full_name: Du, Guangwei
last_name: Du
- first_name: Hai Ning
full_name: Du, Hai Ning
last_name: Du
- first_name: Li Lin
full_name: Du, Li Lin
last_name: Du
- first_name: André
full_name: Du Toit, André
last_name: Du Toit
- first_name: Shao Bin
full_name: Duan, Shao Bin
last_name: Duan
- first_name: Xiaoqiong
full_name: Duan, Xiaoqiong
last_name: Duan
- first_name: Sónia P.
full_name: Duarte, Sónia P.
last_name: Duarte
- first_name: Anna
full_name: Dubrovska, Anna
last_name: Dubrovska
- first_name: Elaine A.
full_name: Dunlop, Elaine A.
last_name: Dunlop
- first_name: Nicolas
full_name: Dupont, Nicolas
last_name: Dupont
- first_name: Raúl V.
full_name: Durán, Raúl V.
last_name: Durán
- first_name: Bilikere S.
full_name: Dwarakanath, Bilikere S.
last_name: Dwarakanath
- first_name: Sergey A.
full_name: Dyshlovoy, Sergey A.
last_name: Dyshlovoy
- first_name: Darius
full_name: Ebrahimi-Fakhari, Darius
last_name: Ebrahimi-Fakhari
- first_name: Leopold
full_name: Eckhart, Leopold
last_name: Eckhart
- first_name: Charles L.
full_name: Edelstein, Charles L.
last_name: Edelstein
- first_name: Thomas
full_name: Efferth, Thomas
last_name: Efferth
- first_name: Eftekhar
full_name: Eftekharpour, Eftekhar
last_name: Eftekharpour
- first_name: Ludwig
full_name: Eichinger, Ludwig
last_name: Eichinger
- first_name: Nabil
full_name: Eid, Nabil
last_name: Eid
- first_name: Tobias
full_name: Eisenberg, Tobias
last_name: Eisenberg
- first_name: N. Tony
full_name: Eissa, N. Tony
last_name: Eissa
- first_name: Sanaa
full_name: Eissa, Sanaa
last_name: Eissa
- first_name: Miriam
full_name: Ejarque, Miriam
last_name: Ejarque
- first_name: Abdeljabar
full_name: El Andaloussi, Abdeljabar
last_name: El Andaloussi
- first_name: Nazira
full_name: El-Hage, Nazira
last_name: El-Hage
- first_name: Shahenda
full_name: El-Naggar, Shahenda
last_name: El-Naggar
- first_name: Anna Maria
full_name: Eleuteri, Anna Maria
last_name: Eleuteri
- first_name: Eman S.
full_name: El-Shafey, Eman S.
last_name: El-Shafey
- first_name: Mohamed
full_name: Elgendy, Mohamed
last_name: Elgendy
- first_name: Aristides G.
full_name: Eliopoulos, Aristides G.
last_name: Eliopoulos
- first_name: María M.
full_name: Elizalde, María M.
last_name: Elizalde
- first_name: Philip M.
full_name: Elks, Philip M.
last_name: Elks
- first_name: Hans Peter
full_name: Elsasser, Hans Peter
last_name: Elsasser
- first_name: Eslam S.
full_name: Elsherbiny, Eslam S.
last_name: Elsherbiny
- first_name: Brooke M.
full_name: Emerling, Brooke M.
last_name: Emerling
- first_name: N. C.Tolga
full_name: Emre, N. C.Tolga
last_name: Emre
- first_name: Christina H.
full_name: Eng, Christina H.
last_name: Eng
- first_name: Nikolai
full_name: Engedal, Nikolai
last_name: Engedal
- first_name: Anna Mart
full_name: Engelbrecht, Anna Mart
last_name: Engelbrecht
- first_name: Agnete S.T.
full_name: Engelsen, Agnete S.T.
last_name: Engelsen
- first_name: Jorrit M.
full_name: Enserink, Jorrit M.
last_name: Enserink
- first_name: Ricardo
full_name: Escalante, Ricardo
last_name: Escalante
- first_name: Audrey
full_name: Esclatine, Audrey
last_name: Esclatine
- first_name: Mafalda
full_name: Escobar-Henriques, Mafalda
last_name: Escobar-Henriques
- first_name: Eeva Liisa
full_name: Eskelinen, Eeva Liisa
last_name: Eskelinen
- first_name: Lucile
full_name: Espert, Lucile
last_name: Espert
- first_name: Makandjou Ola
full_name: Eusebio, Makandjou Ola
last_name: Eusebio
- first_name: Gemma
full_name: Fabrias, Gemma
last_name: Fabrias
- first_name: Cinzia
full_name: Fabrizi, Cinzia
last_name: Fabrizi
- first_name: Antonio
full_name: Facchiano, Antonio
last_name: Facchiano
- first_name: Francesco
full_name: Facchiano, Francesco
last_name: Facchiano
- first_name: Bengt
full_name: Fadeel, Bengt
last_name: Fadeel
- first_name: Claudio
full_name: Fader, Claudio
last_name: Fader
- first_name: Alex C.
full_name: Faesen, Alex C.
last_name: Faesen
- first_name: W. Douglas
full_name: Fairlie, W. Douglas
last_name: Fairlie
- first_name: Alberto
full_name: Falcó, Alberto
last_name: Falcó
- first_name: Bjorn H.
full_name: Falkenburger, Bjorn H.
last_name: Falkenburger
- first_name: Daping
full_name: Fan, Daping
last_name: Fan
- first_name: Jie
full_name: Fan, Jie
last_name: Fan
- first_name: Yanbo
full_name: Fan, Yanbo
last_name: Fan
- first_name: Evandro F.
full_name: Fang, Evandro F.
last_name: Fang
- first_name: Yanshan
full_name: Fang, Yanshan
last_name: Fang
- first_name: Yognqi
full_name: Fang, Yognqi
last_name: Fang
- first_name: Manolis
full_name: Fanto, Manolis
last_name: Fanto
- first_name: Tamar
full_name: Farfel-Becker, Tamar
last_name: Farfel-Becker
- first_name: Mathias
full_name: Faure, Mathias
last_name: Faure
- first_name: Gholamreza
full_name: Fazeli, Gholamreza
last_name: Fazeli
- first_name: Anthony O.
full_name: Fedele, Anthony O.
last_name: Fedele
- first_name: Arthur M.
full_name: Feldman, Arthur M.
last_name: Feldman
- first_name: Du
full_name: Feng, Du
last_name: Feng
- first_name: Jiachun
full_name: Feng, Jiachun
last_name: Feng
- first_name: Lifeng
full_name: Feng, Lifeng
last_name: Feng
- first_name: Yibin
full_name: Feng, Yibin
last_name: Feng
- first_name: Yuchen
full_name: Feng, Yuchen
last_name: Feng
- first_name: Wei
full_name: Feng, Wei
last_name: Feng
- first_name: Thais
full_name: Fenz Araujo, Thais
last_name: Fenz Araujo
- first_name: Thomas A.
full_name: Ferguson, Thomas A.
last_name: Ferguson
- first_name: Álvaro F.
full_name: Fernández, Álvaro F.
last_name: Fernández
- first_name: Jose C.
full_name: Fernandez-Checa, Jose C.
last_name: Fernandez-Checa
- first_name: Sonia
full_name: Fernández-Veledo, Sonia
last_name: Fernández-Veledo
- first_name: Alisdair R.
full_name: Fernie, Alisdair R.
last_name: Fernie
- first_name: Anthony W.
full_name: Ferrante, Anthony W.
last_name: Ferrante
- first_name: Alessandra
full_name: Ferraresi, Alessandra
last_name: Ferraresi
- first_name: Merari F.
full_name: Ferrari, Merari F.
last_name: Ferrari
- first_name: Julio C.B.
full_name: Ferreira, Julio C.B.
last_name: Ferreira
- first_name: Susan
full_name: Ferro-Novick, Susan
last_name: Ferro-Novick
- first_name: Antonio
full_name: Figueras, Antonio
last_name: Figueras
- first_name: Riccardo
full_name: Filadi, Riccardo
last_name: Filadi
- first_name: Nicoletta
full_name: Filigheddu, Nicoletta
last_name: Filigheddu
- first_name: Eduardo
full_name: Filippi-Chiela, Eduardo
last_name: Filippi-Chiela
- first_name: Giuseppe
full_name: Filomeni, Giuseppe
last_name: Filomeni
- first_name: Gian Maria
full_name: Fimia, Gian Maria
last_name: Fimia
- first_name: Vittorio
full_name: Fineschi, Vittorio
last_name: Fineschi
- first_name: Francesca
full_name: Finetti, Francesca
last_name: Finetti
- first_name: Steven
full_name: Finkbeiner, Steven
last_name: Finkbeiner
- first_name: Edward A.
full_name: Fisher, Edward A.
last_name: Fisher
- first_name: Paul B.
full_name: Fisher, Paul B.
last_name: Fisher
- first_name: Flavio
full_name: Flamigni, Flavio
last_name: Flamigni
- first_name: Steven J.
full_name: Fliesler, Steven J.
last_name: Fliesler
- first_name: Trude H.
full_name: Flo, Trude H.
last_name: Flo
- first_name: Ida
full_name: Florance, Ida
last_name: Florance
- first_name: Oliver
full_name: Florey, Oliver
last_name: Florey
- first_name: Tullio
full_name: Florio, Tullio
last_name: Florio
- first_name: Erika
full_name: Fodor, Erika
last_name: Fodor
- first_name: Carlo
full_name: Follo, Carlo
last_name: Follo
- first_name: Edward A.
full_name: Fon, Edward A.
last_name: Fon
- first_name: Antonella
full_name: Forlino, Antonella
last_name: Forlino
- first_name: Francesco
full_name: Fornai, Francesco
last_name: Fornai
- first_name: Paola
full_name: Fortini, Paola
last_name: Fortini
- first_name: Anna
full_name: Fracassi, Anna
last_name: Fracassi
- first_name: Alessandro
full_name: Fraldi, Alessandro
last_name: Fraldi
- first_name: Brunella
full_name: Franco, Brunella
last_name: Franco
- first_name: Rodrigo
full_name: Franco, Rodrigo
last_name: Franco
- first_name: Flavia
full_name: Franconi, Flavia
last_name: Franconi
- first_name: Lisa B.
full_name: Frankel, Lisa B.
last_name: Frankel
- first_name: Scott L.
full_name: Friedman, Scott L.
last_name: Friedman
- first_name: Leopold F.
full_name: Fröhlich, Leopold F.
last_name: Fröhlich
- first_name: Gema
full_name: Frühbeck, Gema
last_name: Frühbeck
- first_name: Jose M.
full_name: Fuentes, Jose M.
last_name: Fuentes
- first_name: Yukio
full_name: Fujiki, Yukio
last_name: Fujiki
- first_name: Naonobu
full_name: Fujita, Naonobu
last_name: Fujita
- first_name: Yuuki
full_name: Fujiwara, Yuuki
last_name: Fujiwara
- first_name: Mitsunori
full_name: Fukuda, Mitsunori
last_name: Fukuda
- first_name: Simone
full_name: Fulda, Simone
last_name: Fulda
- first_name: Luc
full_name: Furic, Luc
last_name: Furic
- first_name: Norihiko
full_name: Furuya, Norihiko
last_name: Furuya
- first_name: Carmela
full_name: Fusco, Carmela
last_name: Fusco
- first_name: Michaela U.
full_name: Gack, Michaela U.
last_name: Gack
- first_name: Lidia
full_name: Gaffke, Lidia
last_name: Gaffke
- first_name: Sehamuddin
full_name: Galadari, Sehamuddin
last_name: Galadari
- first_name: Alessia
full_name: Galasso, Alessia
last_name: Galasso
- first_name: Maria F.
full_name: Galindo, Maria F.
last_name: Galindo
- first_name: Sachith
full_name: Gallolu Kankanamalage, Sachith
last_name: Gallolu Kankanamalage
- first_name: Lorenzo
full_name: Galluzzi, Lorenzo
last_name: Galluzzi
- first_name: Vincent
full_name: Galy, Vincent
last_name: Galy
- first_name: Noor
full_name: Gammoh, Noor
last_name: Gammoh
- first_name: Boyi
full_name: Gan, Boyi
last_name: Gan
- first_name: Ian G.
full_name: Ganley, Ian G.
last_name: Ganley
- first_name: Feng
full_name: Gao, Feng
last_name: Gao
- first_name: Hui
full_name: Gao, Hui
last_name: Gao
- first_name: Minghui
full_name: Gao, Minghui
last_name: Gao
- first_name: Ping
full_name: Gao, Ping
last_name: Gao
- first_name: Shou Jiang
full_name: Gao, Shou Jiang
last_name: Gao
- first_name: Wentao
full_name: Gao, Wentao
last_name: Gao
- first_name: Xiaobo
full_name: Gao, Xiaobo
last_name: Gao
- first_name: Ana
full_name: Garcera, Ana
last_name: Garcera
- first_name: Maria Noé
full_name: Garcia, Maria Noé
last_name: Garcia
- first_name: Verónica E.
full_name: Garcia, Verónica E.
last_name: Garcia
- first_name: Francisco
full_name: García-Del Portillo, Francisco
last_name: García-Del Portillo
- first_name: Vega
full_name: Garcia-Escudero, Vega
last_name: Garcia-Escudero
- first_name: Aracely
full_name: Garcia-Garcia, Aracely
last_name: Garcia-Garcia
- first_name: Marina
full_name: Garcia-Macia, Marina
last_name: Garcia-Macia
- first_name: Diana
full_name: García-Moreno, Diana
last_name: García-Moreno
- first_name: Carmen
full_name: Garcia-Ruiz, Carmen
last_name: Garcia-Ruiz
- first_name: Patricia
full_name: García-Sanz, Patricia
last_name: García-Sanz
- first_name: Abhishek D.
full_name: Garg, Abhishek D.
last_name: Garg
- first_name: Ricardo
full_name: Gargini, Ricardo
last_name: Gargini
- first_name: Tina
full_name: Garofalo, Tina
last_name: Garofalo
- first_name: Robert F.
full_name: Garry, Robert F.
last_name: Garry
- first_name: Nils C.
full_name: Gassen, Nils C.
last_name: Gassen
- first_name: Damian
full_name: Gatica, Damian
last_name: Gatica
- first_name: Liang
full_name: Ge, Liang
last_name: Ge
- first_name: Wanzhong
full_name: Ge, Wanzhong
last_name: Ge
- first_name: Ruth
full_name: Geiss-Friedlander, Ruth
last_name: Geiss-Friedlander
- first_name: Cecilia
full_name: Gelfi, Cecilia
last_name: Gelfi
- first_name: Pascal
full_name: Genschik, Pascal
last_name: Genschik
- first_name: Ian E.
full_name: Gentle, Ian E.
last_name: Gentle
- first_name: Valeria
full_name: Gerbino, Valeria
last_name: Gerbino
- first_name: Christoph
full_name: Gerhardt, Christoph
last_name: Gerhardt
- first_name: Kyla
full_name: Germain, Kyla
last_name: Germain
- first_name: Marc
full_name: Germain, Marc
last_name: Germain
- first_name: David A.
full_name: Gewirtz, David A.
last_name: Gewirtz
- first_name: Elham
full_name: Ghasemipour Afshar, Elham
last_name: Ghasemipour Afshar
- first_name: Saeid
full_name: Ghavami, Saeid
last_name: Ghavami
- first_name: Alessandra
full_name: Ghigo, Alessandra
last_name: Ghigo
- first_name: Manosij
full_name: Ghosh, Manosij
last_name: Ghosh
- first_name: Georgios
full_name: Giamas, Georgios
last_name: Giamas
- first_name: Claudia
full_name: Giampietri, Claudia
last_name: Giampietri
- first_name: Alexandra
full_name: Giatromanolaki, Alexandra
last_name: Giatromanolaki
- first_name: Gary E.
full_name: Gibson, Gary E.
last_name: Gibson
- first_name: Spencer B.
full_name: Gibson, Spencer B.
last_name: Gibson
- first_name: Vanessa
full_name: Ginet, Vanessa
last_name: Ginet
- first_name: Edward
full_name: Giniger, Edward
last_name: Giniger
- first_name: Carlotta
full_name: Giorgi, Carlotta
last_name: Giorgi
- first_name: Henrique
full_name: Girao, Henrique
last_name: Girao
- first_name: Stephen E.
full_name: Girardin, Stephen E.
last_name: Girardin
- first_name: Mridhula
full_name: Giridharan, Mridhula
last_name: Giridharan
- first_name: Sandy
full_name: Giuliano, Sandy
last_name: Giuliano
- first_name: Cecilia
full_name: Giulivi, Cecilia
last_name: Giulivi
- first_name: Sylvie
full_name: Giuriato, Sylvie
last_name: Giuriato
- first_name: Julien
full_name: Giustiniani, Julien
last_name: Giustiniani
- first_name: Alexander
full_name: Gluschko, Alexander
last_name: Gluschko
- first_name: Veit
full_name: Goder, Veit
last_name: Goder
- first_name: Alexander
full_name: Goginashvili, Alexander
last_name: Goginashvili
- first_name: Jakub
full_name: Golab, Jakub
last_name: Golab
- first_name: David C.
full_name: Goldstone, David C.
last_name: Goldstone
- first_name: Anna
full_name: Golebiewska, Anna
last_name: Golebiewska
- first_name: Luciana R.
full_name: Gomes, Luciana R.
last_name: Gomes
- first_name: Rodrigo
full_name: Gomez, Rodrigo
last_name: Gomez
- first_name: Rubén
full_name: Gómez-Sánchez, Rubén
last_name: Gómez-Sánchez
- first_name: Maria Catalina
full_name: Gomez-Puerto, Maria Catalina
last_name: Gomez-Puerto
- first_name: Raquel
full_name: Gomez-Sintes, Raquel
last_name: Gomez-Sintes
- first_name: Qingqiu
full_name: Gong, Qingqiu
last_name: Gong
- first_name: Felix M.
full_name: Goni, Felix M.
last_name: Goni
- first_name: Javier
full_name: González-Gallego, Javier
last_name: González-Gallego
- first_name: Tomas
full_name: Gonzalez-Hernandez, Tomas
last_name: Gonzalez-Hernandez
- first_name: Rosa A.
full_name: Gonzalez-Polo, Rosa A.
last_name: Gonzalez-Polo
- first_name: Jose A.
full_name: Gonzalez-Reyes, Jose A.
last_name: Gonzalez-Reyes
- first_name: Patricia
full_name: González-Rodríguez, Patricia
last_name: González-Rodríguez
- first_name: Ing Swie
full_name: Goping, Ing Swie
last_name: Goping
- first_name: Marina S.
full_name: Gorbatyuk, Marina S.
last_name: Gorbatyuk
- first_name: Nikolai V.
full_name: Gorbunov, Nikolai V.
last_name: Gorbunov
- first_name: Kıvanç
full_name: Görgülü, Kıvanç
last_name: Görgülü
- first_name: Roxana M.
full_name: Gorojod, Roxana M.
last_name: Gorojod
- first_name: Sharon M.
full_name: Gorski, Sharon M.
last_name: Gorski
- first_name: Sandro
full_name: Goruppi, Sandro
last_name: Goruppi
- first_name: Cecilia
full_name: Gotor, Cecilia
last_name: Gotor
- first_name: Roberta A.
full_name: Gottlieb, Roberta A.
last_name: Gottlieb
- first_name: Illana
full_name: Gozes, Illana
last_name: Gozes
- first_name: Devrim
full_name: Gozuacik, Devrim
last_name: Gozuacik
- first_name: Martin
full_name: Graef, Martin
last_name: Graef
- first_name: Markus H.
full_name: Gräler, Markus H.
last_name: Gräler
- first_name: Veronica
full_name: Granatiero, Veronica
last_name: Granatiero
- first_name: Daniel
full_name: Grasso, Daniel
last_name: Grasso
- first_name: Joshua P.
full_name: Gray, Joshua P.
last_name: Gray
- first_name: Douglas R.
full_name: Green, Douglas R.
last_name: Green
- first_name: Alexander
full_name: Greenhough, Alexander
last_name: Greenhough
- first_name: Stephen L.
full_name: Gregory, Stephen L.
last_name: Gregory
- first_name: Edward F.
full_name: Griffin, Edward F.
last_name: Griffin
- first_name: Mark W.
full_name: Grinstaff, Mark W.
last_name: Grinstaff
- first_name: Frederic
full_name: Gros, Frederic
last_name: Gros
- first_name: Charles
full_name: Grose, Charles
last_name: Grose
- first_name: Angelina S.
full_name: Gross, Angelina S.
last_name: Gross
- first_name: Florian
full_name: Gruber, Florian
last_name: Gruber
- first_name: Paolo
full_name: Grumati, Paolo
last_name: Grumati
- first_name: Tilman
full_name: Grune, Tilman
last_name: Grune
- first_name: Xueyan
full_name: Gu, Xueyan
last_name: Gu
- first_name: Jun Lin
full_name: Guan, Jun Lin
last_name: Guan
- first_name: Carlos M.
full_name: Guardia, Carlos M.
last_name: Guardia
- first_name: Kishore
full_name: Guda, Kishore
last_name: Guda
- first_name: Flora
full_name: Guerra, Flora
last_name: Guerra
- first_name: Consuelo
full_name: Guerri, Consuelo
last_name: Guerri
- first_name: Prasun
full_name: Guha, Prasun
last_name: Guha
- first_name: Carlos
full_name: Guillén, Carlos
last_name: Guillén
- first_name: Shashi
full_name: Gujar, Shashi
last_name: Gujar
- first_name: Anna
full_name: Gukovskaya, Anna
last_name: Gukovskaya
- first_name: Ilya
full_name: Gukovsky, Ilya
last_name: Gukovsky
- first_name: Jan
full_name: Gunst, Jan
last_name: Gunst
- first_name: Andreas
full_name: Günther, Andreas
last_name: Günther
- first_name: Anyonya R.
full_name: Guntur, Anyonya R.
last_name: Guntur
- first_name: Chuanyong
full_name: Guo, Chuanyong
last_name: Guo
- first_name: Chun
full_name: Guo, Chun
last_name: Guo
- first_name: Hongqing
full_name: Guo, Hongqing
last_name: Guo
- first_name: Lian Wang
full_name: Guo, Lian Wang
last_name: Guo
- first_name: Ming
full_name: Guo, Ming
last_name: Guo
- first_name: Pawan
full_name: Gupta, Pawan
last_name: Gupta
- first_name: Shashi Kumar
full_name: Gupta, Shashi Kumar
last_name: Gupta
- first_name: Swapnil
full_name: Gupta, Swapnil
last_name: Gupta
- first_name: Veer Bala
full_name: Gupta, Veer Bala
last_name: Gupta
- first_name: Vivek
full_name: Gupta, Vivek
last_name: Gupta
- first_name: Asa B.
full_name: Gustafsson, Asa B.
last_name: Gustafsson
- first_name: David D.
full_name: Gutterman, David D.
last_name: Gutterman
- first_name: Ranjitha
full_name: H.B, Ranjitha
last_name: H.B
- first_name: Annakaisa
full_name: Haapasalo, Annakaisa
last_name: Haapasalo
- first_name: James E.
full_name: Haber, James E.
last_name: Haber
- first_name: Aleksandra
full_name: Hać, Aleksandra
last_name: Hać
- first_name: Shinji
full_name: Hadano, Shinji
last_name: Hadano
- first_name: Anders J.
full_name: Hafrén, Anders J.
last_name: Hafrén
- first_name: Mansour
full_name: Haidar, Mansour
last_name: Haidar
- first_name: Belinda S.
full_name: Hall, Belinda S.
last_name: Hall
- first_name: Gunnel
full_name: Halldén, Gunnel
last_name: Halldén
- first_name: Anne
full_name: Hamacher-Brady, Anne
last_name: Hamacher-Brady
- first_name: Andrea
full_name: Hamann, Andrea
last_name: Hamann
- first_name: Maho
full_name: Hamasaki, Maho
last_name: Hamasaki
- first_name: Weidong
full_name: Han, Weidong
last_name: Han
- first_name: Malene
full_name: Hansen, Malene
last_name: Hansen
- first_name: Phyllis I. .
full_name: Hanson, Phyllis I. .
last_name: Hanson
- first_name: Zijian
full_name: Hao, Zijian
last_name: Hao
- first_name: Masaru
full_name: Harada, Masaru
last_name: Harada
- first_name: Ljubica
full_name: Harhaji-Trajkovic, Ljubica
last_name: Harhaji-Trajkovic
- first_name: Nirmala
full_name: Hariharan, Nirmala
last_name: Hariharan
- first_name: Nigil
full_name: Haroon, Nigil
last_name: Haroon
- first_name: James
full_name: Harris, James
last_name: Harris
- first_name: Takafumi
full_name: Hasegawa, Takafumi
last_name: Hasegawa
- first_name: Noor
full_name: Hasima Nagoor, Noor
last_name: Hasima Nagoor
- first_name: Jeffrey A.
full_name: Haspel, Jeffrey A.
last_name: Haspel
- first_name: Volker
full_name: Haucke, Volker
last_name: Haucke
- first_name: Wayne D.
full_name: Hawkins, Wayne D.
last_name: Hawkins
- first_name: Bruce A.
full_name: Hay, Bruce A.
last_name: Hay
- first_name: Cole M.
full_name: Haynes, Cole M.
last_name: Haynes
- first_name: Soren B.
full_name: Hayrabedyan, Soren B.
last_name: Hayrabedyan
- first_name: Thomas S.
full_name: Hays, Thomas S.
last_name: Hays
- first_name: Congcong
full_name: He, Congcong
last_name: He
- first_name: Qin
full_name: He, Qin
last_name: He
- first_name: Rong Rong
full_name: He, Rong Rong
last_name: He
- first_name: You Wen
full_name: He, You Wen
last_name: He
- first_name: Yu Ying
full_name: He, Yu Ying
last_name: He
- first_name: Yasser
full_name: Heakal, Yasser
last_name: Heakal
- first_name: Alexander M.
full_name: Heberle, Alexander M.
last_name: Heberle
- first_name: J. Fielding
full_name: Hejtmancik, J. Fielding
last_name: Hejtmancik
- first_name: Gudmundur Vignir
full_name: Helgason, Gudmundur Vignir
last_name: Helgason
- first_name: Vanessa
full_name: Henkel, Vanessa
last_name: Henkel
- first_name: Marc
full_name: Herb, Marc
last_name: Herb
- first_name: Alexander
full_name: Hergovich, Alexander
last_name: Hergovich
- first_name: Anna
full_name: Herman-Antosiewicz, Anna
last_name: Herman-Antosiewicz
- first_name: Agustín
full_name: Hernández, Agustín
last_name: Hernández
- first_name: Carlos
full_name: Hernandez, Carlos
last_name: Hernandez
- first_name: Sergio
full_name: Hernandez-Diaz, Sergio
last_name: Hernandez-Diaz
- first_name: Virginia
full_name: Hernandez-Gea, Virginia
last_name: Hernandez-Gea
- first_name: Amaury
full_name: Herpin, Amaury
last_name: Herpin
- first_name: Judit
full_name: Herreros, Judit
last_name: Herreros
- first_name: Javier H.
full_name: Hervás, Javier H.
last_name: Hervás
- first_name: Daniel
full_name: Hesselson, Daniel
last_name: Hesselson
- first_name: Claudio
full_name: Hetz, Claudio
last_name: Hetz
- first_name: Volker T.
full_name: Heussler, Volker T.
last_name: Heussler
- first_name: Yujiro
full_name: Higuchi, Yujiro
last_name: Higuchi
- first_name: Sabine
full_name: Hilfiker, Sabine
last_name: Hilfiker
- first_name: Joseph A.
full_name: Hill, Joseph A.
last_name: Hill
- first_name: William S.
full_name: Hlavacek, William S.
last_name: Hlavacek
- first_name: Emmanuel A.
full_name: Ho, Emmanuel A.
last_name: Ho
- first_name: Idy H.T.
full_name: Ho, Idy H.T.
last_name: Ho
- first_name: Philip Wing Lok
full_name: Ho, Philip Wing Lok
last_name: Ho
- first_name: Shu Leong
full_name: Ho, Shu Leong
last_name: Ho
- first_name: Wan Yun
full_name: Ho, Wan Yun
last_name: Ho
- first_name: G. Aaron
full_name: Hobbs, G. Aaron
last_name: Hobbs
- first_name: Mark
full_name: Hochstrasser, Mark
last_name: Hochstrasser
- first_name: Peter H.M.
full_name: Hoet, Peter H.M.
last_name: Hoet
- first_name: Daniel
full_name: Hofius, Daniel
last_name: Hofius
- first_name: Paul
full_name: Hofman, Paul
last_name: Hofman
- first_name: Annika
full_name: Höhn, Annika
last_name: Höhn
- first_name: Carina I.
full_name: Holmberg, Carina I.
last_name: Holmberg
- first_name: Jose R.
full_name: Hombrebueno, Jose R.
last_name: Hombrebueno
- first_name: Chang Won Hong
full_name: Yi-Ren Hong, Chang Won Hong
last_name: Yi-Ren Hong
- first_name: Lora V.
full_name: Hooper, Lora V.
last_name: Hooper
- first_name: Thorsten
full_name: Hoppe, Thorsten
last_name: Hoppe
- first_name: Rastislav
full_name: Horos, Rastislav
last_name: Horos
- first_name: Yujin
full_name: Hoshida, Yujin
last_name: Hoshida
- first_name: I. Lun
full_name: Hsin, I. Lun
last_name: Hsin
- first_name: Hsin Yun
full_name: Hsu, Hsin Yun
last_name: Hsu
- first_name: Bing
full_name: Hu, Bing
last_name: Hu
- first_name: Dong
full_name: Hu, Dong
last_name: Hu
- first_name: Li Fang
full_name: Hu, Li Fang
last_name: Hu
- first_name: Ming Chang
full_name: Hu, Ming Chang
last_name: Hu
- first_name: Ronggui
full_name: Hu, Ronggui
last_name: Hu
- first_name: Wei
full_name: Hu, Wei
last_name: Hu
- first_name: Yu Chen
full_name: Hu, Yu Chen
last_name: Hu
- first_name: Zhuo Wei
full_name: Hu, Zhuo Wei
last_name: Hu
- first_name: Fang
full_name: Hua, Fang
last_name: Hua
- first_name: Jinlian
full_name: Hua, Jinlian
last_name: Hua
- first_name: Yingqi
full_name: Hua, Yingqi
last_name: Hua
- first_name: Chongmin
full_name: Huan, Chongmin
last_name: Huan
- first_name: Canhua
full_name: Huang, Canhua
last_name: Huang
- first_name: Chuanshu
full_name: Huang, Chuanshu
last_name: Huang
- first_name: Chuanxin
full_name: Huang, Chuanxin
last_name: Huang
- first_name: Chunling
full_name: Huang, Chunling
last_name: Huang
- first_name: Haishan
full_name: Huang, Haishan
last_name: Huang
- first_name: Kun
full_name: Huang, Kun
last_name: Huang
- first_name: Michael L.H.
full_name: Huang, Michael L.H.
last_name: Huang
- first_name: Rui
full_name: Huang, Rui
last_name: Huang
- first_name: Shan
full_name: Huang, Shan
last_name: Huang
- first_name: Tianzhi
full_name: Huang, Tianzhi
last_name: Huang
- first_name: Xing
full_name: Huang, Xing
last_name: Huang
- first_name: Yuxiang Jack
full_name: Huang, Yuxiang Jack
last_name: Huang
- first_name: Tobias B.
full_name: Huber, Tobias B.
last_name: Huber
- first_name: Virginie
full_name: Hubert, Virginie
last_name: Hubert
- first_name: Christian A.
full_name: Hubner, Christian A.
last_name: Hubner
- first_name: Stephanie M.
full_name: Hughes, Stephanie M.
last_name: Hughes
- first_name: William E.
full_name: Hughes, William E.
last_name: Hughes
- first_name: Magali
full_name: Humbert, Magali
last_name: Humbert
- first_name: Gerhard
full_name: Hummer, Gerhard
last_name: Hummer
- first_name: James H.
full_name: Hurley, James H.
last_name: Hurley
- first_name: Sabah
full_name: Hussain, Sabah
last_name: Hussain
- first_name: Salik
full_name: Hussain, Salik
last_name: Hussain
- first_name: Patrick J.
full_name: Hussey, Patrick J.
last_name: Hussey
- first_name: Martina
full_name: Hutabarat, Martina
last_name: Hutabarat
- first_name: Hui Yun
full_name: Hwang, Hui Yun
last_name: Hwang
- first_name: Seungmin
full_name: Hwang, Seungmin
last_name: Hwang
- first_name: Antonio
full_name: Ieni, Antonio
last_name: Ieni
- first_name: Fumiyo
full_name: Ikeda, Fumiyo
last_name: Ikeda
- first_name: Yusuke
full_name: Imagawa, Yusuke
last_name: Imagawa
- first_name: Yuzuru
full_name: Imai, Yuzuru
last_name: Imai
- first_name: Carol
full_name: Imbriano, Carol
last_name: Imbriano
- first_name: Masaya
full_name: Imoto, Masaya
last_name: Imoto
- first_name: Denise M.
full_name: Inman, Denise M.
last_name: Inman
- first_name: Ken
full_name: Inoki, Ken
last_name: Inoki
- first_name: Juan
full_name: Iovanna, Juan
last_name: Iovanna
- first_name: Renato V.
full_name: Iozzo, Renato V.
last_name: Iozzo
- first_name: Giuseppe
full_name: Ippolito, Giuseppe
last_name: Ippolito
- first_name: Javier E.
full_name: Irazoqui, Javier E.
last_name: Irazoqui
- first_name: Pablo
full_name: Iribarren, Pablo
last_name: Iribarren
- first_name: Mohd
full_name: Ishaq, Mohd
last_name: Ishaq
- first_name: Makoto
full_name: Ishikawa, Makoto
last_name: Ishikawa
- first_name: Nestor
full_name: Ishimwe, Nestor
last_name: Ishimwe
- first_name: Ciro
full_name: Isidoro, Ciro
last_name: Isidoro
- first_name: Nahed
full_name: Ismail, Nahed
last_name: Ismail
- first_name: Shohreh
full_name: Issazadeh-Navikas, Shohreh
last_name: Issazadeh-Navikas
- first_name: Eisuke
full_name: Itakura, Eisuke
last_name: Itakura
- first_name: Daisuke
full_name: Ito, Daisuke
last_name: Ito
- first_name: Davor
full_name: Ivankovic, Davor
last_name: Ivankovic
- first_name: Saška
full_name: Ivanova, Saška
last_name: Ivanova
- first_name: Anand Krishnan V.
full_name: Iyer, Anand Krishnan V.
last_name: Iyer
- first_name: José M.
full_name: Izquierdo, José M.
last_name: Izquierdo
- first_name: Masanori
full_name: Izumi, Masanori
last_name: Izumi
- first_name: Marja
full_name: Jäättelä, Marja
last_name: Jäättelä
- first_name: Majid Sakhi
full_name: Jabir, Majid Sakhi
last_name: Jabir
- first_name: William T.
full_name: Jackson, William T.
last_name: Jackson
- first_name: Nadia
full_name: Jacobo-Herrera, Nadia
last_name: Jacobo-Herrera
- first_name: Anne Claire
full_name: Jacomin, Anne Claire
last_name: Jacomin
- first_name: Elise
full_name: Jacquin, Elise
last_name: Jacquin
- first_name: Pooja
full_name: Jadiya, Pooja
last_name: Jadiya
- first_name: Hartmut
full_name: Jaeschke, Hartmut
last_name: Jaeschke
- first_name: Chinnaswamy
full_name: Jagannath, Chinnaswamy
last_name: Jagannath
- first_name: Arjen J.
full_name: Jakobi, Arjen J.
last_name: Jakobi
- first_name: Johan
full_name: Jakobsson, Johan
last_name: Jakobsson
- first_name: Bassam
full_name: Janji, Bassam
last_name: Janji
- first_name: Pidder
full_name: Jansen-Dürr, Pidder
last_name: Jansen-Dürr
- first_name: Patric J.
full_name: Jansson, Patric J.
last_name: Jansson
- first_name: Jonathan
full_name: Jantsch, Jonathan
last_name: Jantsch
- first_name: Sławomir
full_name: Januszewski, Sławomir
last_name: Januszewski
- first_name: Alagie
full_name: Jassey, Alagie
last_name: Jassey
- first_name: Steve
full_name: Jean, Steve
last_name: Jean
- first_name: Hélène
full_name: Jeltsch-David, Hélène
last_name: Jeltsch-David
- first_name: Pavla
full_name: Jendelova, Pavla
last_name: Jendelova
- first_name: Andreas
full_name: Jenny, Andreas
last_name: Jenny
- first_name: Thomas E.
full_name: Jensen, Thomas E.
last_name: Jensen
- first_name: Niels
full_name: Jessen, Niels
last_name: Jessen
- first_name: Jenna L.
full_name: Jewell, Jenna L.
last_name: Jewell
- first_name: Jing
full_name: Ji, Jing
last_name: Ji
- first_name: Lijun
full_name: Jia, Lijun
last_name: Jia
- first_name: Rui
full_name: Jia, Rui
last_name: Jia
- first_name: Liwen
full_name: Jiang, Liwen
last_name: Jiang
- first_name: Qing
full_name: Jiang, Qing
last_name: Jiang
- first_name: Richeng
full_name: Jiang, Richeng
last_name: Jiang
- first_name: Teng
full_name: Jiang, Teng
last_name: Jiang
- first_name: Xuejun
full_name: Jiang, Xuejun
last_name: Jiang
- first_name: Yu
full_name: Jiang, Yu
last_name: Jiang
- first_name: Maria
full_name: Jimenez-Sanchez, Maria
last_name: Jimenez-Sanchez
- first_name: Eun Jung
full_name: Jin, Eun Jung
last_name: Jin
- first_name: Fengyan
full_name: Jin, Fengyan
last_name: Jin
- first_name: Hongchuan
full_name: Jin, Hongchuan
last_name: Jin
- first_name: Li
full_name: Jin, Li
last_name: Jin
- first_name: Luqi
full_name: Jin, Luqi
last_name: Jin
- first_name: Meiyan
full_name: Jin, Meiyan
last_name: Jin
- first_name: Si
full_name: Jin, Si
last_name: Jin
- first_name: Eun Kyeong
full_name: Jo, Eun Kyeong
last_name: Jo
- first_name: Carine
full_name: Joffre, Carine
last_name: Joffre
- first_name: Terje
full_name: Johansen, Terje
last_name: Johansen
- first_name: Gail V.W.
full_name: Johnson, Gail V.W.
last_name: Johnson
- first_name: Simon A.
full_name: Johnston, Simon A.
last_name: Johnston
- first_name: Eija
full_name: Jokitalo, Eija
last_name: Jokitalo
- first_name: Mohit Kumar
full_name: Jolly, Mohit Kumar
last_name: Jolly
- first_name: Leo A.B.
full_name: Joosten, Leo A.B.
last_name: Joosten
- first_name: Joaquin
full_name: Jordan, Joaquin
last_name: Jordan
- first_name: Bertrand
full_name: Joseph, Bertrand
last_name: Joseph
- first_name: Dianwen
full_name: Ju, Dianwen
last_name: Ju
- first_name: Jeong Sun
full_name: Ju, Jeong Sun
last_name: Ju
- first_name: Jingfang
full_name: Ju, Jingfang
last_name: Ju
- first_name: Esmeralda
full_name: Juárez, Esmeralda
last_name: Juárez
- first_name: Delphine
full_name: Judith, Delphine
last_name: Judith
- first_name: Gábor
full_name: Juhász, Gábor
last_name: Juhász
- first_name: Youngsoo
full_name: Jun, Youngsoo
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- first_name: Chang Hwa
full_name: Jung, Chang Hwa
last_name: Jung
- first_name: Sung Chul
full_name: Jung, Sung Chul
last_name: Jung
- first_name: Yong Keun
full_name: Jung, Yong Keun
last_name: Jung
- first_name: Heinz
full_name: Jungbluth, Heinz
last_name: Jungbluth
- first_name: Johannes
full_name: Jungverdorben, Johannes
last_name: Jungverdorben
- first_name: Steffen
full_name: Just, Steffen
last_name: Just
- first_name: Kai
full_name: Kaarniranta, Kai
last_name: Kaarniranta
- first_name: Allen
full_name: Kaasik, Allen
last_name: Kaasik
- first_name: Tomohiro
full_name: Kabuta, Tomohiro
last_name: Kabuta
- first_name: Daniel
full_name: Kaganovich, Daniel
last_name: Kaganovich
- first_name: Alon
full_name: Kahana, Alon
last_name: Kahana
- first_name: Renate
full_name: Kain, Renate
last_name: Kain
- first_name: Shinjo
full_name: Kajimura, Shinjo
last_name: Kajimura
- first_name: Maria
full_name: Kalamvoki, Maria
last_name: Kalamvoki
- first_name: Manjula
full_name: Kalia, Manjula
last_name: Kalia
- first_name: Danuta S.
full_name: Kalinowski, Danuta S.
last_name: Kalinowski
- first_name: Nina
full_name: Kaludercic, Nina
last_name: Kaludercic
- first_name: Ioanna
full_name: Kalvari, Ioanna
last_name: Kalvari
- first_name: Joanna
full_name: Kaminska, Joanna
last_name: Kaminska
- first_name: Vitaliy O.
full_name: Kaminskyy, Vitaliy O.
last_name: Kaminskyy
- first_name: Hiromitsu
full_name: Kanamori, Hiromitsu
last_name: Kanamori
- first_name: Keizo
full_name: Kanasaki, Keizo
last_name: Kanasaki
- first_name: Chanhee
full_name: Kang, Chanhee
last_name: Kang
- first_name: Rui
full_name: Kang, Rui
last_name: Kang
- first_name: Sang Sun
full_name: Kang, Sang Sun
last_name: Kang
- first_name: Senthilvelrajan
full_name: Kaniyappan, Senthilvelrajan
last_name: Kaniyappan
- first_name: Tomotake
full_name: Kanki, Tomotake
last_name: Kanki
- first_name: Thirumala Devi
full_name: Kanneganti, Thirumala Devi
last_name: Kanneganti
- first_name: Anumantha G.
full_name: Kanthasamy, Anumantha G.
last_name: Kanthasamy
- first_name: Arthi
full_name: Kanthasamy, Arthi
last_name: Kanthasamy
- first_name: Marc
full_name: Kantorow, Marc
last_name: Kantorow
- first_name: Orsolya
full_name: Kapuy, Orsolya
last_name: Kapuy
- first_name: Michalis V.
full_name: Karamouzis, Michalis V.
last_name: Karamouzis
- first_name: Md Razaul
full_name: Karim, Md Razaul
last_name: Karim
- first_name: Parimal
full_name: Karmakar, Parimal
last_name: Karmakar
- first_name: Rajesh G.
full_name: Katare, Rajesh G.
last_name: Katare
- first_name: Masaru
full_name: Kato, Masaru
last_name: Kato
- first_name: Stefan H.E.
full_name: Kaufmann, Stefan H.E.
last_name: Kaufmann
- first_name: Anu
full_name: Kauppinen, Anu
last_name: Kauppinen
- first_name: Gur P.
full_name: Kaushal, Gur P.
last_name: Kaushal
- first_name: Susmita
full_name: Kaushik, Susmita
last_name: Kaushik
- first_name: Kiyoshi
full_name: Kawasaki, Kiyoshi
last_name: Kawasaki
- first_name: Kemal
full_name: Kazan, Kemal
last_name: Kazan
- first_name: Po Yuan
full_name: Ke, Po Yuan
last_name: Ke
- first_name: Damien J.
full_name: Keating, Damien J.
last_name: Keating
- first_name: Ursula
full_name: Keber, Ursula
last_name: Keber
- first_name: John H.
full_name: Kehrl, John H.
last_name: Kehrl
- first_name: Kate E.
full_name: Keller, Kate E.
last_name: Keller
- first_name: Christian W.
full_name: Keller, Christian W.
last_name: Keller
- first_name: Jongsook Kim
full_name: Kemper, Jongsook Kim
last_name: Kemper
- first_name: Candia M.
full_name: Kenific, Candia M.
last_name: Kenific
- first_name: Oliver
full_name: Kepp, Oliver
last_name: Kepp
- first_name: Stephanie
full_name: Kermorgant, Stephanie
last_name: Kermorgant
- first_name: Andreas
full_name: Kern, Andreas
last_name: Kern
- first_name: Robin
full_name: Ketteler, Robin
last_name: Ketteler
- first_name: Tom G.
full_name: Keulers, Tom G.
last_name: Keulers
- first_name: Boris
full_name: Khalfin, Boris
last_name: Khalfin
- first_name: Hany
full_name: Khalil, Hany
last_name: Khalil
- first_name: Bilon
full_name: Khambu, Bilon
last_name: Khambu
- first_name: Shahid Y.
full_name: Khan, Shahid Y.
last_name: Khan
- first_name: Vinoth Kumar Megraj
full_name: Khandelwal, Vinoth Kumar Megraj
last_name: Khandelwal
- first_name: Rekha
full_name: Khandia, Rekha
last_name: Khandia
- first_name: Widuri
full_name: Kho, Widuri
last_name: Kho
- first_name: Noopur V.
full_name: Khobrekar, Noopur V.
last_name: Khobrekar
- first_name: Sataree
full_name: Khuansuwan, Sataree
last_name: Khuansuwan
- first_name: Mukhran
full_name: Khundadze, Mukhran
last_name: Khundadze
- first_name: Samuel A.
full_name: Killackey, Samuel A.
last_name: Killackey
- first_name: Dasol
full_name: Kim, Dasol
last_name: Kim
- first_name: Deok Ryong
full_name: Kim, Deok Ryong
last_name: Kim
- first_name: Do Hyung
full_name: Kim, Do Hyung
last_name: Kim
- first_name: Dong Eun
full_name: Kim, Dong Eun
last_name: Kim
- first_name: Eun Young
full_name: Kim, Eun Young
last_name: Kim
- first_name: Eun Kyoung
full_name: Kim, Eun Kyoung
last_name: Kim
- first_name: Hak Rim
full_name: Kim, Hak Rim
last_name: Kim
- first_name: Hee Sik
full_name: Kim, Hee Sik
last_name: Kim
- first_name: Unknown
full_name: Hyung-Ryong Kim, Unknown
last_name: Hyung-Ryong Kim
- first_name: Jeong Hun
full_name: Kim, Jeong Hun
last_name: Kim
- first_name: Jin Kyung
full_name: Kim, Jin Kyung
last_name: Kim
- first_name: Jin Hoi
full_name: Kim, Jin Hoi
last_name: Kim
- first_name: Joungmok
full_name: Kim, Joungmok
last_name: Kim
- first_name: Ju Hwan
full_name: Kim, Ju Hwan
last_name: Kim
- first_name: Keun Il
full_name: Kim, Keun Il
last_name: Kim
- first_name: Peter K.
full_name: Kim, Peter K.
last_name: Kim
- first_name: Seong Jun
full_name: Kim, Seong Jun
last_name: Kim
- first_name: Scot R.
full_name: Kimball, Scot R.
last_name: Kimball
- first_name: Adi
full_name: Kimchi, Adi
last_name: Kimchi
- first_name: Alec C.
full_name: Kimmelman, Alec C.
last_name: Kimmelman
- first_name: Tomonori
full_name: Kimura, Tomonori
last_name: Kimura
- first_name: Matthew A.
full_name: King, Matthew A.
last_name: King
- first_name: Kerri J.
full_name: Kinghorn, Kerri J.
last_name: Kinghorn
- first_name: Conan G.
full_name: Kinsey, Conan G.
last_name: Kinsey
- first_name: Vladimir
full_name: Kirkin, Vladimir
last_name: Kirkin
- first_name: Lorrie A.
full_name: Kirshenbaum, Lorrie A.
last_name: Kirshenbaum
- first_name: Sergey L.
full_name: Kiselev, Sergey L.
last_name: Kiselev
- first_name: Shuji
full_name: Kishi, Shuji
last_name: Kishi
- first_name: Katsuhiko
full_name: Kitamoto, Katsuhiko
last_name: Kitamoto
- first_name: Yasushi
full_name: Kitaoka, Yasushi
last_name: Kitaoka
- first_name: Kaio
full_name: Kitazato, Kaio
last_name: Kitazato
- first_name: Richard N.
full_name: Kitsis, Richard N.
last_name: Kitsis
- first_name: Josef T.
full_name: Kittler, Josef T.
last_name: Kittler
- first_name: Ole
full_name: Kjaerulff, Ole
last_name: Kjaerulff
- first_name: Peter S.
full_name: Klein, Peter S.
last_name: Klein
- first_name: Thomas
full_name: Klopstock, Thomas
last_name: Klopstock
- first_name: Jochen
full_name: Klucken, Jochen
last_name: Klucken
- first_name: Helene
full_name: Knævelsrud, Helene
last_name: Knævelsrud
- first_name: Roland L.
full_name: Knorr, Roland L.
last_name: Knorr
- first_name: Ben C.B.
full_name: Ko, Ben C.B.
last_name: Ko
- first_name: Fred
full_name: Ko, Fred
last_name: Ko
- first_name: Jiunn Liang
full_name: Ko, Jiunn Liang
last_name: Ko
- first_name: Hotaka
full_name: Kobayashi, Hotaka
last_name: Kobayashi
- first_name: Satoru
full_name: Kobayashi, Satoru
last_name: Kobayashi
- first_name: Ina
full_name: Koch, Ina
last_name: Koch
- first_name: Jan C.
full_name: Koch, Jan C.
last_name: Koch
- first_name: Ulrich
full_name: Koenig, Ulrich
last_name: Koenig
- first_name: Donat
full_name: Kögel, Donat
last_name: Kögel
- first_name: Young Ho
full_name: Koh, Young Ho
last_name: Koh
- first_name: Masato
full_name: Koike, Masato
last_name: Koike
- first_name: Sepp D.
full_name: Kohlwein, Sepp D.
last_name: Kohlwein
- first_name: Nur M.
full_name: Kocaturk, Nur M.
last_name: Kocaturk
- first_name: Masaaki
full_name: Komatsu, Masaaki
last_name: Komatsu
- first_name: Jeannette
full_name: König, Jeannette
last_name: König
- first_name: Toru
full_name: Kono, Toru
last_name: Kono
- first_name: Benjamin T.
full_name: Kopp, Benjamin T.
last_name: Kopp
- first_name: Tamas
full_name: Korcsmaros, Tamas
last_name: Korcsmaros
- first_name: Gözde
full_name: Korkmaz, Gözde
last_name: Korkmaz
- first_name: Viktor I.
full_name: Korolchuk, Viktor I.
last_name: Korolchuk
- first_name: Mónica Suárez
full_name: Korsnes, Mónica Suárez
last_name: Korsnes
- first_name: Ali
full_name: Koskela, Ali
last_name: Koskela
- first_name: Janaiah
full_name: Kota, Janaiah
last_name: Kota
- first_name: Yaichiro
full_name: Kotake, Yaichiro
last_name: Kotake
- first_name: Monica L.
full_name: Kotler, Monica L.
last_name: Kotler
- first_name: Yanjun
full_name: Kou, Yanjun
last_name: Kou
- first_name: Michael I.
full_name: Koukourakis, Michael I.
last_name: Koukourakis
- first_name: Evangelos
full_name: Koustas, Evangelos
last_name: Koustas
- first_name: Attila L.
full_name: Kovacs, Attila L.
last_name: Kovacs
- first_name: Tibor
full_name: Kovács, Tibor
last_name: Kovács
- first_name: Daisuke
full_name: Koya, Daisuke
last_name: Koya
- first_name: Tomohiro
full_name: Kozako, Tomohiro
last_name: Kozako
- first_name: Claudine
full_name: Kraft, Claudine
last_name: Kraft
- first_name: Dimitri
full_name: Krainc, Dimitri
last_name: Krainc
- first_name: Helmut
full_name: Krämer, Helmut
last_name: Krämer
- first_name: Anna D.
full_name: Krasnodembskaya, Anna D.
last_name: Krasnodembskaya
- first_name: Carole
full_name: Kretz-Remy, Carole
last_name: Kretz-Remy
- first_name: Guido
full_name: Kroemer, Guido
last_name: Kroemer
- first_name: Nicholas T.
full_name: Ktistakis, Nicholas T.
last_name: Ktistakis
- first_name: Kazuyuki
full_name: Kuchitsu, Kazuyuki
last_name: Kuchitsu
- first_name: Sabine
full_name: Kuenen, Sabine
last_name: Kuenen
- first_name: Lars
full_name: Kuerschner, Lars
last_name: Kuerschner
- first_name: Thomas
full_name: Kukar, Thomas
last_name: Kukar
- first_name: Ajay
full_name: Kumar, Ajay
last_name: Kumar
- first_name: Ashok
full_name: Kumar, Ashok
last_name: Kumar
- first_name: Deepak
full_name: Kumar, Deepak
last_name: Kumar
- first_name: Dhiraj
full_name: Kumar, Dhiraj
last_name: Kumar
- first_name: Sharad
full_name: Kumar, Sharad
last_name: Kumar
- first_name: Shinji
full_name: Kume, Shinji
last_name: Kume
- first_name: Caroline
full_name: Kumsta, Caroline
last_name: Kumsta
- first_name: Chanakya N.
full_name: Kundu, Chanakya N.
last_name: Kundu
- first_name: Mondira
full_name: Kundu, Mondira
last_name: Kundu
- first_name: Ajaikumar B.
full_name: Kunnumakkara, Ajaikumar B.
last_name: Kunnumakkara
- first_name: Lukasz
full_name: Kurgan, Lukasz
last_name: Kurgan
- first_name: Tatiana G.
full_name: Kutateladze, Tatiana G.
last_name: Kutateladze
- first_name: Ozlem
full_name: Kutlu, Ozlem
last_name: Kutlu
- first_name: Seong Ae
full_name: Kwak, Seong Ae
last_name: Kwak
- first_name: Ho Jeong
full_name: Kwon, Ho Jeong
last_name: Kwon
- first_name: Taeg Kyu
full_name: Kwon, Taeg Kyu
last_name: Kwon
- first_name: Yong Tae
full_name: Kwon, Yong Tae
last_name: Kwon
- first_name: Irene
full_name: Kyrmizi, Irene
last_name: Kyrmizi
- first_name: Albert
full_name: La Spada, Albert
last_name: La Spada
- first_name: Patrick
full_name: Labonté, Patrick
last_name: Labonté
- first_name: Sylvain
full_name: Ladoire, Sylvain
last_name: Ladoire
- first_name: Ilaria
full_name: Laface, Ilaria
last_name: Laface
- first_name: Frank
full_name: Lafont, Frank
last_name: Lafont
- first_name: Diane C.
full_name: Lagace, Diane C.
last_name: Lagace
- first_name: Vikramjit
full_name: Lahiri, Vikramjit
last_name: Lahiri
- first_name: Zhibing
full_name: Lai, Zhibing
last_name: Lai
- first_name: Angela S.
full_name: Laird, Angela S.
last_name: Laird
- first_name: Aparna
full_name: Lakkaraju, Aparna
last_name: Lakkaraju
- first_name: Trond
full_name: Lamark, Trond
last_name: Lamark
- first_name: Sheng Hui
full_name: Lan, Sheng Hui
last_name: Lan
- first_name: Ane
full_name: Landajuela, Ane
last_name: Landajuela
- first_name: Darius J.R.
full_name: Lane, Darius J.R.
last_name: Lane
- first_name: Jon D.
full_name: Lane, Jon D.
last_name: Lane
- first_name: Charles H.
full_name: Lang, Charles H.
last_name: Lang
- first_name: Carsten
full_name: Lange, Carsten
last_name: Lange
- first_name: Ülo
full_name: Langel, Ülo
last_name: Langel
- first_name: Rupert
full_name: Langer, Rupert
last_name: Langer
- first_name: Pierre
full_name: Lapaquette, Pierre
last_name: Lapaquette
- first_name: Jocelyn
full_name: Laporte, Jocelyn
last_name: Laporte
- first_name: Nicholas F.
full_name: Larusso, Nicholas F.
last_name: Larusso
- first_name: Isabel
full_name: Lastres-Becker, Isabel
last_name: Lastres-Becker
- first_name: Wilson Chun Yu
full_name: Lau, Wilson Chun Yu
last_name: Lau
- first_name: Gordon W.
full_name: Laurie, Gordon W.
last_name: Laurie
- first_name: Sergio
full_name: Lavandero, Sergio
last_name: Lavandero
- first_name: Betty Yuen Kwan
full_name: Law, Betty Yuen Kwan
last_name: Law
- first_name: Helen Ka Wai
full_name: Law, Helen Ka Wai
last_name: Law
- first_name: Rob
full_name: Layfield, Rob
last_name: Layfield
- first_name: Weidong
full_name: Le, Weidong
last_name: Le
- first_name: Herve
full_name: Le Stunff, Herve
last_name: Le Stunff
- first_name: Alexandre Y.
full_name: Leary, Alexandre Y.
last_name: Leary
- first_name: Jean Jacques
full_name: Lebrun, Jean Jacques
last_name: Lebrun
- first_name: Lionel Y.W.
full_name: Leck, Lionel Y.W.
last_name: Leck
- first_name: Jean Philippe
full_name: Leduc-Gaudet, Jean Philippe
last_name: Leduc-Gaudet
- first_name: Changwook
full_name: Lee, Changwook
last_name: Lee
- first_name: Chung Pei
full_name: Lee, Chung Pei
last_name: Lee
- first_name: Da Hye
full_name: Lee, Da Hye
last_name: Lee
- first_name: Edward B.
full_name: Lee, Edward B.
last_name: Lee
- first_name: Erinna F.
full_name: Lee, Erinna F.
last_name: Lee
- first_name: Gyun Min
full_name: Lee, Gyun Min
last_name: Lee
- first_name: He Jin
full_name: Lee, He Jin
last_name: Lee
- first_name: Heung Kyu
full_name: Lee, Heung Kyu
last_name: Lee
- first_name: Jae Man
full_name: Lee, Jae Man
last_name: Lee
- first_name: Jason S.
full_name: Lee, Jason S.
last_name: Lee
- first_name: Jin A.
full_name: Lee, Jin A.
last_name: Lee
- first_name: Joo Yong
full_name: Lee, Joo Yong
last_name: Lee
- first_name: Jun Hee
full_name: Lee, Jun Hee
last_name: Lee
- first_name: Michael
full_name: Lee, Michael
last_name: Lee
- first_name: Min Goo
full_name: Lee, Min Goo
last_name: Lee
- first_name: Min Jae
full_name: Lee, Min Jae
last_name: Lee
- first_name: Myung Shik
full_name: Lee, Myung Shik
last_name: Lee
- first_name: Sang Yoon
full_name: Lee, Sang Yoon
last_name: Lee
- first_name: Seung Jae
full_name: Lee, Seung Jae
last_name: Lee
- first_name: Stella Y.
full_name: Lee, Stella Y.
last_name: Lee
- first_name: Sung Bae
full_name: Lee, Sung Bae
last_name: Lee
- first_name: Won Hee
full_name: Lee, Won Hee
last_name: Lee
- first_name: Ying Ray
full_name: Lee, Ying Ray
last_name: Lee
- first_name: Yong Ho
full_name: Lee, Yong Ho
last_name: Lee
- first_name: Youngil
full_name: Lee, Youngil
last_name: Lee
- first_name: Christophe
full_name: Lefebvre, Christophe
last_name: Lefebvre
- first_name: Renaud
full_name: Legouis, Renaud
last_name: Legouis
- first_name: Yu L.
full_name: Lei, Yu L.
last_name: Lei
- first_name: Yuchen
full_name: Lei, Yuchen
last_name: Lei
- first_name: Sergey
full_name: Leikin, Sergey
last_name: Leikin
- first_name: Gerd
full_name: Leitinger, Gerd
last_name: Leitinger
- first_name: Leticia
full_name: Lemus, Leticia
last_name: Lemus
- first_name: Shuilong
full_name: Leng, Shuilong
last_name: Leng
- first_name: Olivia
full_name: Lenoir, Olivia
last_name: Lenoir
- first_name: Guido
full_name: Lenz, Guido
last_name: Lenz
- first_name: Heinz Josef
full_name: Lenz, Heinz Josef
last_name: Lenz
- first_name: Paola
full_name: Lenzi, Paola
last_name: Lenzi
- first_name: Yolanda
full_name: León, Yolanda
last_name: León
- first_name: Andréia M.
full_name: Leopoldino, Andréia M.
last_name: Leopoldino
- first_name: Christoph
full_name: Leschczyk, Christoph
last_name: Leschczyk
- first_name: Stina
full_name: Leskelä, Stina
last_name: Leskelä
- first_name: Elisabeth
full_name: Letellier, Elisabeth
last_name: Letellier
- first_name: Chi Ting
full_name: Leung, Chi Ting
last_name: Leung
- first_name: Po Sing
full_name: Leung, Po Sing
last_name: Leung
- first_name: Jeremy S.
full_name: Leventhal, Jeremy S.
last_name: Leventhal
- first_name: Beth
full_name: Levine, Beth
last_name: Levine
- first_name: Patrick A.
full_name: Lewis, Patrick A.
last_name: Lewis
- first_name: Klaus
full_name: Ley, Klaus
last_name: Ley
- first_name: Bin
full_name: Li, Bin
last_name: Li
- first_name: Da Qiang
full_name: Li, Da Qiang
last_name: Li
- first_name: Jianming
full_name: Li, Jianming
last_name: Li
- first_name: Jing
full_name: Li, Jing
last_name: Li
- first_name: Jiong
full_name: Li, Jiong
last_name: Li
- first_name: Ke
full_name: Li, Ke
last_name: Li
- first_name: Liwu
full_name: Li, Liwu
last_name: Li
- first_name: Mei
full_name: Li, Mei
last_name: Li
- first_name: Min
full_name: Li, Min
last_name: Li
- first_name: Min
full_name: Li, Min
last_name: Li
- first_name: Ming
full_name: Li, Ming
last_name: Li
- first_name: Mingchuan
full_name: Li, Mingchuan
last_name: Li
- first_name: Pin Lan
full_name: Li, Pin Lan
last_name: Li
- first_name: Ming Qing
full_name: Li, Ming Qing
last_name: Li
- first_name: Qing
full_name: Li, Qing
last_name: Li
- first_name: Sheng
full_name: Li, Sheng
last_name: Li
- first_name: Tiangang
full_name: Li, Tiangang
last_name: Li
- first_name: Wei
full_name: Li, Wei
last_name: Li
- first_name: Wenming
full_name: Li, Wenming
last_name: Li
- first_name: Xue
full_name: Li, Xue
last_name: Li
- first_name: Yi Ping
full_name: Li, Yi Ping
last_name: Li
- first_name: Yuan
full_name: Li, Yuan
last_name: Li
- first_name: Zhiqiang
full_name: Li, Zhiqiang
last_name: Li
- first_name: Zhiyong
full_name: Li, Zhiyong
last_name: Li
- first_name: Zhiyuan
full_name: Li, Zhiyuan
last_name: Li
- first_name: Jiqin
full_name: Lian, Jiqin
last_name: Lian
- first_name: Chengyu
full_name: Liang, Chengyu
last_name: Liang
- first_name: Qiangrong
full_name: Liang, Qiangrong
last_name: Liang
- first_name: Weicheng
full_name: Liang, Weicheng
last_name: Liang
- first_name: Yongheng
full_name: Liang, Yongheng
last_name: Liang
- first_name: Yong Tian
full_name: Liang, Yong Tian
last_name: Liang
- first_name: Guanghong
full_name: Liao, Guanghong
last_name: Liao
- first_name: Lujian
full_name: Liao, Lujian
last_name: Liao
- first_name: Mingzhi
full_name: Liao, Mingzhi
last_name: Liao
- first_name: Yung Feng
full_name: Liao, Yung Feng
last_name: Liao
- first_name: Mariangela
full_name: Librizzi, Mariangela
last_name: Librizzi
- first_name: Pearl P.Y.
full_name: Lie, Pearl P.Y.
last_name: Lie
- first_name: Mary A.
full_name: Lilly, Mary A.
last_name: Lilly
- first_name: Hyunjung J.
full_name: Lim, Hyunjung J.
last_name: Lim
- first_name: Thania R.R.
full_name: Lima, Thania R.R.
last_name: Lima
- first_name: Federica
full_name: Limana, Federica
last_name: Limana
- first_name: Chao
full_name: Lin, Chao
last_name: Lin
- first_name: Chih Wen
full_name: Lin, Chih Wen
last_name: Lin
- first_name: Dar Shong
full_name: Lin, Dar Shong
last_name: Lin
- first_name: Fu Cheng
full_name: Lin, Fu Cheng
last_name: Lin
- first_name: Jiandie D.
full_name: Lin, Jiandie D.
last_name: Lin
- first_name: Kurt M.
full_name: Lin, Kurt M.
last_name: Lin
- first_name: Kwang Huei
full_name: Lin, Kwang Huei
last_name: Lin
- first_name: Liang Tzung
full_name: Lin, Liang Tzung
last_name: Lin
- first_name: Pei Hui
full_name: Lin, Pei Hui
last_name: Lin
- first_name: Qiong
full_name: Lin, Qiong
last_name: Lin
- first_name: Shaofeng
full_name: Lin, Shaofeng
last_name: Lin
- first_name: Su Ju
full_name: Lin, Su Ju
last_name: Lin
- first_name: Wenyu
full_name: Lin, Wenyu
last_name: Lin
- first_name: Xueying
full_name: Lin, Xueying
last_name: Lin
- first_name: Yao Xin
full_name: Lin, Yao Xin
last_name: Lin
- first_name: Yee Shin
full_name: Lin, Yee Shin
last_name: Lin
- first_name: Rafael
full_name: Linden, Rafael
last_name: Linden
- first_name: Paula
full_name: Lindner, Paula
last_name: Lindner
- first_name: Shuo Chien
full_name: Ling, Shuo Chien
last_name: Ling
- first_name: Paul
full_name: Lingor, Paul
last_name: Lingor
- first_name: Amelia K.
full_name: Linnemann, Amelia K.
last_name: Linnemann
- first_name: Yih Cherng
full_name: Liou, Yih Cherng
last_name: Liou
- first_name: Marta M.
full_name: Lipinski, Marta M.
last_name: Lipinski
- first_name: Saška
full_name: Lipovšek, Saška
last_name: Lipovšek
- first_name: Vitor A.
full_name: Lira, Vitor A.
last_name: Lira
- first_name: Natalia
full_name: Lisiak, Natalia
last_name: Lisiak
- first_name: Paloma B.
full_name: Liton, Paloma B.
last_name: Liton
- first_name: Chao
full_name: Liu, Chao
last_name: Liu
- first_name: Ching Hsuan
full_name: Liu, Ching Hsuan
last_name: Liu
- first_name: Chun Feng
full_name: Liu, Chun Feng
last_name: Liu
- first_name: Cui Hua
full_name: Liu, Cui Hua
last_name: Liu
- first_name: Fang
full_name: Liu, Fang
last_name: Liu
- first_name: Hao
full_name: Liu, Hao
last_name: Liu
- first_name: Hsiao Sheng
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last_name: Liu
- first_name: Hua Feng
full_name: Liu, Hua Feng
last_name: Liu
- first_name: Huifang
full_name: Liu, Huifang
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- first_name: Jia
full_name: Liu, Jia
last_name: Liu
- first_name: Jing
full_name: Liu, Jing
last_name: Liu
- first_name: Julia
full_name: Liu, Julia
last_name: Liu
- first_name: Leyuan
full_name: Liu, Leyuan
last_name: Liu
- first_name: Longhua
full_name: Liu, Longhua
last_name: Liu
- first_name: Meilian
full_name: Liu, Meilian
last_name: Liu
- first_name: Qin
full_name: Liu, Qin
last_name: Liu
- first_name: Wei
full_name: Liu, Wei
last_name: Liu
- first_name: Wende
full_name: Liu, Wende
last_name: Liu
- first_name: Xiao Hong
full_name: Liu, Xiao Hong
last_name: Liu
- first_name: Xiaodong
full_name: Liu, Xiaodong
last_name: Liu
- first_name: Xingguo
full_name: Liu, Xingguo
last_name: Liu
- first_name: Xu
full_name: Liu, Xu
last_name: Liu
- first_name: Xuedong
full_name: Liu, Xuedong
last_name: Liu
- first_name: Yanfen
full_name: Liu, Yanfen
last_name: Liu
- first_name: Yang
full_name: Liu, Yang
last_name: Liu
- first_name: Yang
full_name: Liu, Yang
last_name: Liu
- first_name: Yueyang
full_name: Liu, Yueyang
last_name: Liu
- first_name: Yule
full_name: Liu, Yule
last_name: Liu
- first_name: J. Andrew
full_name: Livingston, J. Andrew
last_name: Livingston
- first_name: Gerard
full_name: Lizard, Gerard
last_name: Lizard
- first_name: Jose M.
full_name: Lizcano, Jose M.
last_name: Lizcano
- first_name: Senka
full_name: Ljubojevic-Holzer, Senka
last_name: Ljubojevic-Holzer
- first_name: Matilde E.
full_name: Lleonart, Matilde E.
last_name: Lleonart
- first_name: David
full_name: Llobet-Navàs, David
last_name: Llobet-Navàs
- first_name: Alicia
full_name: Llorente, Alicia
last_name: Llorente
- first_name: Chih Hung
full_name: Lo, Chih Hung
last_name: Lo
- first_name: Damián
full_name: Lobato-Márquez, Damián
last_name: Lobato-Márquez
- first_name: Qi
full_name: Long, Qi
last_name: Long
- first_name: Yun Chau
full_name: Long, Yun Chau
last_name: Long
- first_name: Ben
full_name: Loos, Ben
last_name: Loos
- first_name: Julia A.
full_name: Loos, Julia A.
last_name: Loos
- first_name: Manuela G.
full_name: López, Manuela G.
last_name: López
- first_name: Guillermo
full_name: López-Doménech, Guillermo
last_name: López-Doménech
- first_name: José Antonio
full_name: López-Guerrero, José Antonio
last_name: López-Guerrero
- first_name: Ana T.
full_name: López-Jiménez, Ana T.
last_name: López-Jiménez
- first_name: Óscar
full_name: López-Pérez, Óscar
last_name: López-Pérez
- first_name: Israel
full_name: López-Valero, Israel
last_name: López-Valero
- first_name: Magdalena J.
full_name: Lorenowicz, Magdalena J.
last_name: Lorenowicz
- first_name: Mar
full_name: Lorente, Mar
last_name: Lorente
- first_name: Peter
full_name: Lorincz, Peter
last_name: Lorincz
- first_name: Laura
full_name: Lossi, Laura
last_name: Lossi
- first_name: Sophie
full_name: Lotersztajn, Sophie
last_name: Lotersztajn
- first_name: Penny E.
full_name: Lovat, Penny E.
last_name: Lovat
- first_name: Jonathan F.
full_name: Lovell, Jonathan F.
last_name: Lovell
- first_name: Alenka
full_name: Lovy, Alenka
last_name: Lovy
- first_name: Péter
full_name: Lőw, Péter
last_name: Lőw
- first_name: Guang
full_name: Lu, Guang
last_name: Lu
- first_name: Haocheng
full_name: Lu, Haocheng
last_name: Lu
- first_name: Jia Hong
full_name: Lu, Jia Hong
last_name: Lu
- first_name: Jin Jian
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last_name: Lu
- first_name: Mengji
full_name: Lu, Mengji
last_name: Lu
- first_name: Shuyan
full_name: Lu, Shuyan
last_name: Lu
- first_name: Alessandro
full_name: Luciani, Alessandro
last_name: Luciani
- first_name: John M.
full_name: Lucocq, John M.
last_name: Lucocq
- first_name: Paula
full_name: Ludovico, Paula
last_name: Ludovico
- first_name: Micah A.
full_name: Luftig, Micah A.
last_name: Luftig
- first_name: Morten
full_name: Luhr, Morten
last_name: Luhr
- first_name: Diego
full_name: Luis-Ravelo, Diego
last_name: Luis-Ravelo
- first_name: Julian J.
full_name: Lum, Julian J.
last_name: Lum
- first_name: Liany
full_name: Luna-Dulcey, Liany
last_name: Luna-Dulcey
- first_name: Anders H.
full_name: Lund, Anders H.
last_name: Lund
- first_name: Viktor K.
full_name: Lund, Viktor K.
last_name: Lund
- first_name: Jan D.
full_name: Lünemann, Jan D.
last_name: Lünemann
- first_name: Patrick
full_name: Lüningschrör, Patrick
last_name: Lüningschrör
- first_name: Honglin
full_name: Luo, Honglin
last_name: Luo
- first_name: Rongcan
full_name: Luo, Rongcan
last_name: Luo
- first_name: Shouqing
full_name: Luo, Shouqing
last_name: Luo
- first_name: Zhi
full_name: Luo, Zhi
last_name: Luo
- first_name: Claudio
full_name: Luparello, Claudio
last_name: Luparello
- first_name: Bernhard
full_name: Lüscher, Bernhard
last_name: Lüscher
- first_name: Luan
full_name: Luu, Luan
last_name: Luu
- first_name: Alex
full_name: Lyakhovich, Alex
last_name: Lyakhovich
- first_name: Konstantin G.
full_name: Lyamzaev, Konstantin G.
last_name: Lyamzaev
- first_name: Alf Håkon
full_name: Lystad, Alf Håkon
last_name: Lystad
- first_name: Lyubomyr
full_name: Lytvynchuk, Lyubomyr
last_name: Lytvynchuk
- first_name: Alvin C.
full_name: Ma, Alvin C.
last_name: Ma
- first_name: Changle
full_name: Ma, Changle
last_name: Ma
- first_name: Mengxiao
full_name: Ma, Mengxiao
last_name: Ma
- first_name: Ning Fang
full_name: Ma, Ning Fang
last_name: Ma
- first_name: Quan Hong
full_name: Ma, Quan Hong
last_name: Ma
- first_name: Xinliang
full_name: Ma, Xinliang
last_name: Ma
- first_name: Yueyun
full_name: Ma, Yueyun
last_name: Ma
- first_name: Zhenyi
full_name: Ma, Zhenyi
last_name: Ma
- first_name: Ormond A.
full_name: Macdougald, Ormond A.
last_name: Macdougald
- first_name: Fernando
full_name: Macian, Fernando
last_name: Macian
- first_name: Gustavo C.
full_name: Macintosh, Gustavo C.
last_name: Macintosh
- first_name: Jeffrey P.
full_name: Mackeigan, Jeffrey P.
last_name: Mackeigan
- first_name: Kay F.
full_name: Macleod, Kay F.
last_name: Macleod
- first_name: Sandra
full_name: Maday, Sandra
last_name: Maday
- first_name: Frank
full_name: Madeo, Frank
last_name: Madeo
- first_name: Muniswamy
full_name: Madesh, Muniswamy
last_name: Madesh
- first_name: Tobias
full_name: Madl, Tobias
last_name: Madl
- first_name: Julio
full_name: Madrigal-Matute, Julio
last_name: Madrigal-Matute
- first_name: Akiko
full_name: Maeda, Akiko
last_name: Maeda
- first_name: Yasuhiro
full_name: Maejima, Yasuhiro
last_name: Maejima
- first_name: Marta
full_name: Magarinos, Marta
last_name: Magarinos
- first_name: Poornima
full_name: Mahavadi, Poornima
last_name: Mahavadi
- first_name: Emiliano
full_name: Maiani, Emiliano
last_name: Maiani
- first_name: Kenneth
full_name: Maiese, Kenneth
last_name: Maiese
- first_name: Panchanan
full_name: Maiti, Panchanan
last_name: Maiti
- first_name: Maria Chiara
full_name: Maiuri, Maria Chiara
last_name: Maiuri
- first_name: Barbara
full_name: Majello, Barbara
last_name: Majello
- first_name: Michael B.
full_name: Major, Michael B.
last_name: Major
- first_name: Elena
full_name: Makareeva, Elena
last_name: Makareeva
- first_name: Fayaz
full_name: Malik, Fayaz
last_name: Malik
- first_name: Karthik
full_name: Mallilankaraman, Karthik
last_name: Mallilankaraman
- first_name: Walter
full_name: Malorni, Walter
last_name: Malorni
- first_name: Alina
full_name: Maloyan, Alina
last_name: Maloyan
- first_name: Najiba
full_name: Mammadova, Najiba
last_name: Mammadova
- first_name: Gene Chi Wai
full_name: Man, Gene Chi Wai
last_name: Man
- first_name: Federico
full_name: Manai, Federico
last_name: Manai
- first_name: Joseph D.
full_name: Mancias, Joseph D.
last_name: Mancias
- first_name: Eva Maria
full_name: Mandelkow, Eva Maria
last_name: Mandelkow
- first_name: Michael A.
full_name: Mandell, Michael A.
last_name: Mandell
- first_name: Angelo A.
full_name: Manfredi, Angelo A.
last_name: Manfredi
- first_name: Masoud H.
full_name: Manjili, Masoud H.
last_name: Manjili
- first_name: Ravi
full_name: Manjithaya, Ravi
last_name: Manjithaya
- first_name: Patricio
full_name: Manque, Patricio
last_name: Manque
- first_name: Bella B.
full_name: Manshian, Bella B.
last_name: Manshian
- first_name: Raquel
full_name: Manzano, Raquel
last_name: Manzano
- first_name: Claudia
full_name: Manzoni, Claudia
last_name: Manzoni
- first_name: Kai
full_name: Mao, Kai
last_name: Mao
- first_name: Cinzia
full_name: Marchese, Cinzia
last_name: Marchese
- first_name: Sandrine
full_name: Marchetti, Sandrine
last_name: Marchetti
- first_name: Anna Maria
full_name: Marconi, Anna Maria
last_name: Marconi
- first_name: Fabrizio
full_name: Marcucci, Fabrizio
last_name: Marcucci
- first_name: Stefania
full_name: Mardente, Stefania
last_name: Mardente
- first_name: Olga A.
full_name: Mareninova, Olga A.
last_name: Mareninova
- first_name: Marta
full_name: Margeta, Marta
last_name: Margeta
- first_name: Muriel
full_name: Mari, Muriel
last_name: Mari
- first_name: Sara
full_name: Marinelli, Sara
last_name: Marinelli
- first_name: Oliviero
full_name: Marinelli, Oliviero
last_name: Marinelli
- first_name: Guillermo
full_name: Mariño, Guillermo
last_name: Mariño
- first_name: Sofia
full_name: Mariotto, Sofia
last_name: Mariotto
- first_name: Richard S.
full_name: Marshall, Richard S.
last_name: Marshall
- first_name: Mark R.
full_name: Marten, Mark R.
last_name: Marten
- first_name: Sascha
full_name: Martens, Sascha
last_name: Martens
- first_name: Alexandre P.J.
full_name: Martin, Alexandre P.J.
last_name: Martin
- first_name: Katie R.
full_name: Martin, Katie R.
last_name: Martin
- first_name: Sara
full_name: Martin, Sara
last_name: Martin
- first_name: Shaun
full_name: Martin, Shaun
last_name: Martin
- first_name: Adrián
full_name: Martín-Segura, Adrián
last_name: Martín-Segura
- first_name: Miguel A.
full_name: Martín-Acebes, Miguel A.
last_name: Martín-Acebes
- first_name: Inmaculada
full_name: Martin-Burriel, Inmaculada
last_name: Martin-Burriel
- first_name: Marcos
full_name: Martin-Rincon, Marcos
last_name: Martin-Rincon
- first_name: Paloma
full_name: Martin-Sanz, Paloma
last_name: Martin-Sanz
- first_name: José A.
full_name: Martina, José A.
last_name: Martina
- first_name: Wim
full_name: Martinet, Wim
last_name: Martinet
- first_name: Aitor
full_name: Martinez, Aitor
last_name: Martinez
- first_name: Ana
full_name: Martinez, Ana
last_name: Martinez
- first_name: Jennifer
full_name: Martinez, Jennifer
last_name: Martinez
- first_name: Moises
full_name: Martinez Velazquez, Moises
last_name: Martinez Velazquez
- first_name: Nuria
full_name: Martinez-Lopez, Nuria
last_name: Martinez-Lopez
- first_name: Marta
full_name: Martinez-Vicente, Marta
last_name: Martinez-Vicente
- first_name: Daniel O.
full_name: Martins, Daniel O.
last_name: Martins
- first_name: Joilson O.
full_name: Martins, Joilson O.
last_name: Martins
- first_name: Waleska K.
full_name: Martins, Waleska K.
last_name: Martins
- first_name: Tania
full_name: Martins-Marques, Tania
last_name: Martins-Marques
- first_name: Emanuele
full_name: Marzetti, Emanuele
last_name: Marzetti
- first_name: Shashank
full_name: Masaldan, Shashank
last_name: Masaldan
- first_name: Celine
full_name: Masclaux-Daubresse, Celine
last_name: Masclaux-Daubresse
- first_name: Douglas G.
full_name: Mashek, Douglas G.
last_name: Mashek
- first_name: Valentina
full_name: Massa, Valentina
last_name: Massa
- first_name: Lourdes
full_name: Massieu, Lourdes
last_name: Massieu
- first_name: Glenn R.
full_name: Masson, Glenn R.
last_name: Masson
- first_name: Laura
full_name: Masuelli, Laura
last_name: Masuelli
- first_name: Anatoliy I.
full_name: Masyuk, Anatoliy I.
last_name: Masyuk
- first_name: Tetyana V.
full_name: Masyuk, Tetyana V.
last_name: Masyuk
- first_name: Paola
full_name: Matarrese, Paola
last_name: Matarrese
- first_name: Ander
full_name: Matheu, Ander
last_name: Matheu
- first_name: Satoaki
full_name: Matoba, Satoaki
last_name: Matoba
- first_name: Sachiko
full_name: Matsuzaki, Sachiko
last_name: Matsuzaki
- first_name: Pamela
full_name: Mattar, Pamela
last_name: Mattar
- first_name: Alessandro
full_name: Matte, Alessandro
last_name: Matte
- first_name: Domenico
full_name: Mattoscio, Domenico
last_name: Mattoscio
- first_name: José L.
full_name: Mauriz, José L.
last_name: Mauriz
- first_name: Mario
full_name: Mauthe, Mario
last_name: Mauthe
- first_name: Caroline
full_name: Mauvezin, Caroline
last_name: Mauvezin
- first_name: Emanual
full_name: Maverakis, Emanual
last_name: Maverakis
- first_name: Paola
full_name: Maycotte, Paola
last_name: Maycotte
- first_name: Johanna
full_name: Mayer, Johanna
last_name: Mayer
- first_name: Gianluigi
full_name: Mazzoccoli, Gianluigi
last_name: Mazzoccoli
- first_name: Cristina
full_name: Mazzoni, Cristina
last_name: Mazzoni
- first_name: Joseph R.
full_name: Mazzulli, Joseph R.
last_name: Mazzulli
- first_name: Nami
full_name: Mccarty, Nami
last_name: Mccarty
- first_name: Christine
full_name: Mcdonald, Christine
last_name: Mcdonald
- first_name: Mitchell R.
full_name: Mcgill, Mitchell R.
last_name: Mcgill
- first_name: Sharon L.
full_name: Mckenna, Sharon L.
last_name: Mckenna
- first_name: Beth Ann
full_name: Mclaughlin, Beth Ann
last_name: Mclaughlin
- first_name: Fionn
full_name: Mcloughlin, Fionn
last_name: Mcloughlin
- first_name: Mark A.
full_name: Mcniven, Mark A.
last_name: Mcniven
- first_name: Thomas G.
full_name: Mcwilliams, Thomas G.
last_name: Mcwilliams
- first_name: Fatima
full_name: Mechta-Grigoriou, Fatima
last_name: Mechta-Grigoriou
- first_name: Tania Catarina
full_name: Medeiros, Tania Catarina
last_name: Medeiros
- first_name: Diego L.
full_name: Medina, Diego L.
last_name: Medina
- first_name: Lynn A.
full_name: Megeney, Lynn A.
last_name: Megeney
- first_name: Klara
full_name: Megyeri, Klara
last_name: Megyeri
- first_name: Maryam
full_name: Mehrpour, Maryam
last_name: Mehrpour
- first_name: Jawahar L.
full_name: Mehta, Jawahar L.
last_name: Mehta
- first_name: Alfred J.
full_name: Meijer, Alfred J.
last_name: Meijer
- first_name: Annemarie H.
full_name: Meijer, Annemarie H.
last_name: Meijer
- first_name: Jakob
full_name: Mejlvang, Jakob
last_name: Mejlvang
- first_name: Alicia
full_name: Meléndez, Alicia
last_name: Meléndez
- first_name: Annette
full_name: Melk, Annette
last_name: Melk
- first_name: Gonen
full_name: Memisoglu, Gonen
last_name: Memisoglu
- first_name: Alexandrina F.
full_name: Mendes, Alexandrina F.
last_name: Mendes
- first_name: Delong
full_name: Meng, Delong
last_name: Meng
- first_name: Fei
full_name: Meng, Fei
last_name: Meng
- first_name: Tian
full_name: Meng, Tian
last_name: Meng
- first_name: Rubem
full_name: Menna-Barreto, Rubem
last_name: Menna-Barreto
- first_name: Manoj B.
full_name: Menon, Manoj B.
last_name: Menon
- first_name: Carol
full_name: Mercer, Carol
last_name: Mercer
- first_name: Anne E.
full_name: Mercier, Anne E.
last_name: Mercier
- first_name: Jean Louis
full_name: Mergny, Jean Louis
last_name: Mergny
- first_name: Adalberto
full_name: Merighi, Adalberto
last_name: Merighi
- first_name: Seth D.
full_name: Merkley, Seth D.
last_name: Merkley
- first_name: Giuseppe
full_name: Merla, Giuseppe
last_name: Merla
- first_name: Volker
full_name: Meske, Volker
last_name: Meske
- first_name: Ana Cecilia
full_name: Mestre, Ana Cecilia
last_name: Mestre
- first_name: Shree Padma
full_name: Metur, Shree Padma
last_name: Metur
- first_name: Christian
full_name: Meyer, Christian
last_name: Meyer
- first_name: Hemmo
full_name: Meyer, Hemmo
last_name: Meyer
- first_name: Wenyi
full_name: Mi, Wenyi
last_name: Mi
- first_name: Jeanne
full_name: Mialet-Perez, Jeanne
last_name: Mialet-Perez
- first_name: Junying
full_name: Miao, Junying
last_name: Miao
- first_name: Lucia
full_name: Micale, Lucia
last_name: Micale
- first_name: Yasuo
full_name: Miki, Yasuo
last_name: Miki
- first_name: Enrico
full_name: Milan, Enrico
last_name: Milan
- first_name: Małgorzata
full_name: Milczarek, Małgorzata
last_name: Milczarek
- first_name: Dana L.
full_name: Miller, Dana L.
last_name: Miller
- first_name: Samuel I.
full_name: Miller, Samuel I.
last_name: Miller
- first_name: Silke
full_name: Miller, Silke
last_name: Miller
- first_name: Steven W.
full_name: Millward, Steven W.
last_name: Millward
- first_name: Ira
full_name: Milosevic, Ira
last_name: Milosevic
- first_name: Elena A.
full_name: Minina, Elena A.
last_name: Minina
- first_name: Hamed
full_name: Mirzaei, Hamed
last_name: Mirzaei
- first_name: Hamid Reza
full_name: Mirzaei, Hamid Reza
last_name: Mirzaei
- first_name: Mehdi
full_name: Mirzaei, Mehdi
last_name: Mirzaei
- first_name: Amit
full_name: Mishra, Amit
last_name: Mishra
- first_name: Nandita
full_name: Mishra, Nandita
last_name: Mishra
- first_name: Paras Kumar
full_name: Mishra, Paras Kumar
last_name: Mishra
- first_name: Maja
full_name: Misirkic Marjanovic, Maja
last_name: Misirkic Marjanovic
- first_name: Roberta
full_name: Misasi, Roberta
last_name: Misasi
- first_name: Amit
full_name: Misra, Amit
last_name: Misra
- first_name: Gabriella
full_name: Misso, Gabriella
last_name: Misso
- first_name: Claire
full_name: Mitchell, Claire
last_name: Mitchell
- first_name: Geraldine
full_name: Mitou, Geraldine
last_name: Mitou
- first_name: Tetsuji
full_name: Miura, Tetsuji
last_name: Miura
- first_name: Shigeki
full_name: Miyamoto, Shigeki
last_name: Miyamoto
- first_name: Makoto
full_name: Miyazaki, Makoto
last_name: Miyazaki
- first_name: Mitsunori
full_name: Miyazaki, Mitsunori
last_name: Miyazaki
- first_name: Taiga
full_name: Miyazaki, Taiga
last_name: Miyazaki
- first_name: Keisuke
full_name: Miyazawa, Keisuke
last_name: Miyazawa
- first_name: Noboru
full_name: Mizushima, Noboru
last_name: Mizushima
- first_name: Trine H.
full_name: Mogensen, Trine H.
last_name: Mogensen
- first_name: Baharia
full_name: Mograbi, Baharia
last_name: Mograbi
- first_name: Reza
full_name: Mohammadinejad, Reza
last_name: Mohammadinejad
- first_name: Yasir
full_name: Mohamud, Yasir
last_name: Mohamud
- first_name: Abhishek
full_name: Mohanty, Abhishek
last_name: Mohanty
- first_name: Sipra
full_name: Mohapatra, Sipra
last_name: Mohapatra
- first_name: Torsten
full_name: Möhlmann, Torsten
last_name: Möhlmann
- first_name: Asif
full_name: Mohmmed, Asif
last_name: Mohmmed
- first_name: Anna
full_name: Moles, Anna
last_name: Moles
- first_name: Kelle H.
full_name: Moley, Kelle H.
last_name: Moley
- first_name: Maurizio
full_name: Molinari, Maurizio
last_name: Molinari
- first_name: Vincenzo
full_name: Mollace, Vincenzo
last_name: Mollace
- first_name: Andreas Buch
full_name: Møller, Andreas Buch
last_name: Møller
- first_name: Bertrand
full_name: Mollereau, Bertrand
last_name: Mollereau
- first_name: Faustino
full_name: Mollinedo, Faustino
last_name: Mollinedo
- first_name: Costanza
full_name: Montagna, Costanza
last_name: Montagna
- first_name: Mervyn J.
full_name: Monteiro, Mervyn J.
last_name: Monteiro
- first_name: Andrea
full_name: Montella, Andrea
last_name: Montella
- first_name: L. Ruth
full_name: Montes, L. Ruth
last_name: Montes
- first_name: Barbara
full_name: Montico, Barbara
last_name: Montico
- first_name: Vinod K.
full_name: Mony, Vinod K.
last_name: Mony
- first_name: Giacomo
full_name: Monzio Compagnoni, Giacomo
last_name: Monzio Compagnoni
- first_name: Michael N.
full_name: Moore, Michael N.
last_name: Moore
- first_name: Mohammad A.
full_name: Moosavi, Mohammad A.
last_name: Moosavi
- first_name: Ana L.
full_name: Mora, Ana L.
last_name: Mora
- first_name: Marina
full_name: Mora, Marina
last_name: Mora
- first_name: David
full_name: Morales-Alamo, David
last_name: Morales-Alamo
- first_name: Rosario
full_name: Moratalla, Rosario
last_name: Moratalla
- first_name: Paula I.
full_name: Moreira, Paula I.
last_name: Moreira
- first_name: Elena
full_name: Morelli, Elena
last_name: Morelli
- first_name: Sandra
full_name: Moreno, Sandra
last_name: Moreno
- first_name: Daniel
full_name: Moreno-Blas, Daniel
last_name: Moreno-Blas
- first_name: Viviana
full_name: Moresi, Viviana
last_name: Moresi
- first_name: Benjamin
full_name: Morga, Benjamin
last_name: Morga
- first_name: Alwena H.
full_name: Morgan, Alwena H.
last_name: Morgan
- first_name: Fabrice
full_name: Morin, Fabrice
last_name: Morin
- first_name: Hideaki
full_name: Morishita, Hideaki
last_name: Morishita
- first_name: Orson L.
full_name: Moritz, Orson L.
last_name: Moritz
- first_name: Mariko
full_name: Moriyama, Mariko
last_name: Moriyama
- first_name: Yuji
full_name: Moriyasu, Yuji
last_name: Moriyasu
- first_name: Manuela
full_name: Morleo, Manuela
last_name: Morleo
- first_name: Eugenia
full_name: Morselli, Eugenia
last_name: Morselli
- first_name: Jose F.
full_name: Moruno-Manchon, Jose F.
last_name: Moruno-Manchon
- first_name: Jorge
full_name: Moscat, Jorge
last_name: Moscat
- first_name: Serge
full_name: Mostowy, Serge
last_name: Mostowy
- first_name: Elisa
full_name: Motori, Elisa
last_name: Motori
- first_name: Andrea Felinto
full_name: Moura, Andrea Felinto
last_name: Moura
- first_name: Naima
full_name: Moustaid-Moussa, Naima
last_name: Moustaid-Moussa
- first_name: Maria
full_name: Mrakovcic, Maria
last_name: Mrakovcic
- first_name: Gabriel
full_name: Muciño-Hernández, Gabriel
last_name: Muciño-Hernández
- first_name: Anupam
full_name: Mukherjee, Anupam
last_name: Mukherjee
- first_name: Subhadip
full_name: Mukhopadhyay, Subhadip
last_name: Mukhopadhyay
- first_name: Jean M.
full_name: Mulcahy Levy, Jean M.
last_name: Mulcahy Levy
- first_name: Victoriano
full_name: Mulero, Victoriano
last_name: Mulero
- first_name: Sylviane
full_name: Muller, Sylviane
last_name: Muller
- first_name: Christian
full_name: Münch, Christian
last_name: Münch
- first_name: Ashok
full_name: Munjal, Ashok
last_name: Munjal
- first_name: Pura
full_name: Munoz-Canoves, Pura
last_name: Munoz-Canoves
- first_name: Teresa
full_name: Muñoz-Galdeano, Teresa
last_name: Muñoz-Galdeano
- first_name: Christian
full_name: Münz, Christian
last_name: Münz
- first_name: Tomokazu
full_name: Murakawa, Tomokazu
last_name: Murakawa
- first_name: Claudia
full_name: Muratori, Claudia
last_name: Muratori
- first_name: Brona M.
full_name: Murphy, Brona M.
last_name: Murphy
- first_name: J. Patrick
full_name: Murphy, J. Patrick
last_name: Murphy
- first_name: Aditya
full_name: Murthy, Aditya
last_name: Murthy
- first_name: Timo T.
full_name: Myöhänen, Timo T.
last_name: Myöhänen
- first_name: Indira U.
full_name: Mysorekar, Indira U.
last_name: Mysorekar
- first_name: Jennifer
full_name: Mytych, Jennifer
last_name: Mytych
- first_name: Seyed Mohammad
full_name: Nabavi, Seyed Mohammad
last_name: Nabavi
- first_name: Massimo
full_name: Nabissi, Massimo
last_name: Nabissi
- first_name: Péter
full_name: Nagy, Péter
last_name: Nagy
- first_name: Jihoon
full_name: Nah, Jihoon
last_name: Nah
- first_name: Aimable
full_name: Nahimana, Aimable
last_name: Nahimana
- first_name: Ichiro
full_name: Nakagawa, Ichiro
last_name: Nakagawa
- first_name: Ken
full_name: Nakamura, Ken
last_name: Nakamura
- first_name: Hitoshi
full_name: Nakatogawa, Hitoshi
last_name: Nakatogawa
- first_name: Shyam S.
full_name: Nandi, Shyam S.
last_name: Nandi
- first_name: Meera
full_name: Nanjundan, Meera
last_name: Nanjundan
- first_name: Monica
full_name: Nanni, Monica
last_name: Nanni
- first_name: Gennaro
full_name: Napolitano, Gennaro
last_name: Napolitano
- first_name: Roberta
full_name: Nardacci, Roberta
last_name: Nardacci
- first_name: Masashi
full_name: Narita, Masashi
last_name: Narita
- first_name: Melissa
full_name: Nassif, Melissa
last_name: Nassif
- first_name: Ilana
full_name: Nathan, Ilana
last_name: Nathan
- first_name: Manabu
full_name: Natsumeda, Manabu
last_name: Natsumeda
- first_name: Ryno J.
full_name: Naude, Ryno J.
last_name: Naude
- first_name: Christin
full_name: Naumann, Christin
last_name: Naumann
- first_name: Olaia
full_name: Naveiras, Olaia
last_name: Naveiras
- first_name: Fatemeh
full_name: Navid, Fatemeh
last_name: Navid
- first_name: Steffan T.
full_name: Nawrocki, Steffan T.
last_name: Nawrocki
- first_name: Taras Y.
full_name: Nazarko, Taras Y.
last_name: Nazarko
- first_name: Francesca
full_name: Nazio, Francesca
last_name: Nazio
- first_name: Florentina
full_name: Negoita, Florentina
last_name: Negoita
- first_name: Thomas
full_name: Neill, Thomas
last_name: Neill
- first_name: Amanda L.
full_name: Neisch, Amanda L.
last_name: Neisch
- first_name: Luca M.
full_name: Neri, Luca M.
last_name: Neri
- first_name: Mihai G.
full_name: Netea, Mihai G.
last_name: Netea
- first_name: Patrick
full_name: Neubert, Patrick
last_name: Neubert
- first_name: Thomas P.
full_name: Neufeld, Thomas P.
last_name: Neufeld
- first_name: Dietbert
full_name: Neumann, Dietbert
last_name: Neumann
- first_name: Albert
full_name: Neutzner, Albert
last_name: Neutzner
- first_name: Phillip T.
full_name: Newton, Phillip T.
last_name: Newton
- first_name: Paul A.
full_name: Ney, Paul A.
last_name: Ney
- first_name: Ioannis P.
full_name: Nezis, Ioannis P.
last_name: Nezis
- first_name: Charlene C.W.
full_name: Ng, Charlene C.W.
last_name: Ng
- first_name: Tzi Bun
full_name: Ng, Tzi Bun
last_name: Ng
- first_name: Hang T.T.
full_name: Nguyen, Hang T.T.
last_name: Nguyen
- first_name: Long T.
full_name: Nguyen, Long T.
last_name: Nguyen
- first_name: Hong Min
full_name: Ni, Hong Min
last_name: Ni
- first_name: Clíona
full_name: Ní Cheallaigh, Clíona
last_name: Ní Cheallaigh
- first_name: Zhenhong
full_name: Ni, Zhenhong
last_name: Ni
- first_name: M. Celeste
full_name: Nicolao, M. Celeste
last_name: Nicolao
- first_name: Francesco
full_name: Nicoli, Francesco
last_name: Nicoli
- first_name: Manuel
full_name: Nieto-Diaz, Manuel
last_name: Nieto-Diaz
- first_name: Per
full_name: Nilsson, Per
last_name: Nilsson
- first_name: Shunbin
full_name: Ning, Shunbin
last_name: Ning
- first_name: Rituraj
full_name: Niranjan, Rituraj
last_name: Niranjan
- first_name: Hiroshi
full_name: Nishimune, Hiroshi
last_name: Nishimune
- first_name: Mireia
full_name: Niso-Santano, Mireia
last_name: Niso-Santano
- first_name: Ralph A.
full_name: Nixon, Ralph A.
last_name: Nixon
- first_name: Annalisa
full_name: Nobili, Annalisa
last_name: Nobili
- first_name: Clevio
full_name: Nobrega, Clevio
last_name: Nobrega
- first_name: Takeshi
full_name: Noda, Takeshi
last_name: Noda
- first_name: Uxía
full_name: Nogueira-Recalde, Uxía
last_name: Nogueira-Recalde
- first_name: Trevor M.
full_name: Nolan, Trevor M.
last_name: Nolan
- first_name: Ivan
full_name: Nombela, Ivan
last_name: Nombela
- first_name: Ivana
full_name: Novak, Ivana
last_name: Novak
- first_name: Beatriz
full_name: Novoa, Beatriz
last_name: Novoa
- first_name: Takashi
full_name: Nozawa, Takashi
last_name: Nozawa
- first_name: Nobuyuki
full_name: Nukina, Nobuyuki
last_name: Nukina
- first_name: Carmen
full_name: Nussbaum-Krammer, Carmen
last_name: Nussbaum-Krammer
- first_name: Jesper
full_name: Nylandsted, Jesper
last_name: Nylandsted
- first_name: Tracey R.
full_name: O’Donovan, Tracey R.
last_name: O’Donovan
- first_name: Seónadh M.
full_name: O’Leary, Seónadh M.
last_name: O’Leary
- first_name: Eyleen J.
full_name: O’Rourke, Eyleen J.
last_name: O’Rourke
- first_name: Mary P.
full_name: O’Sullivan, Mary P.
last_name: O’Sullivan
- first_name: Timothy E.
full_name: O’Sullivan, Timothy E.
last_name: O’Sullivan
- first_name: Salvatore
full_name: Oddo, Salvatore
last_name: Oddo
- first_name: Ina
full_name: Oehme, Ina
last_name: Oehme
- first_name: Michinaga
full_name: Ogawa, Michinaga
last_name: Ogawa
- first_name: Eric
full_name: Ogier-Denis, Eric
last_name: Ogier-Denis
- first_name: Margret H.
full_name: Ogmundsdottir, Margret H.
last_name: Ogmundsdottir
- first_name: Besim
full_name: Ogretmen, Besim
last_name: Ogretmen
- first_name: Goo Taeg
full_name: Oh, Goo Taeg
last_name: Oh
- first_name: Seon Hee
full_name: Oh, Seon Hee
last_name: Oh
- first_name: Young J.
full_name: Oh, Young J.
last_name: Oh
- first_name: Takashi
full_name: Ohama, Takashi
last_name: Ohama
- first_name: Yohei
full_name: Ohashi, Yohei
last_name: Ohashi
- first_name: Masaki
full_name: Ohmuraya, Masaki
last_name: Ohmuraya
- first_name: Vasileios
full_name: Oikonomou, Vasileios
last_name: Oikonomou
- first_name: Rani
full_name: Ojha, Rani
last_name: Ojha
- first_name: Koji
full_name: Okamoto, Koji
last_name: Okamoto
- first_name: Hitoshi
full_name: Okazawa, Hitoshi
last_name: Okazawa
- first_name: Masahide
full_name: Oku, Masahide
last_name: Oku
- first_name: Sara
full_name: Oliván, Sara
last_name: Oliván
- first_name: Jorge M.A.
full_name: Oliveira, Jorge M.A.
last_name: Oliveira
- first_name: Michael
full_name: Ollmann, Michael
last_name: Ollmann
- first_name: James A.
full_name: Olzmann, James A.
last_name: Olzmann
- first_name: Shakib
full_name: Omari, Shakib
last_name: Omari
- first_name: M. Bishr
full_name: Omary, M. Bishr
last_name: Omary
- first_name: Gizem
full_name: Önal, Gizem
last_name: Önal
- first_name: Martin
full_name: Ondrej, Martin
last_name: Ondrej
- first_name: Sang Bing
full_name: Ong, Sang Bing
last_name: Ong
- first_name: Sang Ging
full_name: Ong, Sang Ging
last_name: Ong
- first_name: Anna
full_name: Onnis, Anna
last_name: Onnis
- first_name: Juan A.
full_name: Orellana, Juan A.
last_name: Orellana
- first_name: Sara
full_name: Orellana-Muñoz, Sara
last_name: Orellana-Muñoz
- first_name: Maria Del Mar
full_name: Ortega-Villaizan, Maria Del Mar
last_name: Ortega-Villaizan
- first_name: Xilma R.
full_name: Ortiz-Gonzalez, Xilma R.
last_name: Ortiz-Gonzalez
- first_name: Elena
full_name: Ortona, Elena
last_name: Ortona
- first_name: Heinz D.
full_name: Osiewacz, Heinz D.
last_name: Osiewacz
- first_name: Abdel Hamid K.
full_name: Osman, Abdel Hamid K.
last_name: Osman
- first_name: Rosario
full_name: Osta, Rosario
last_name: Osta
- first_name: Marisa S.
full_name: Otegui, Marisa S.
last_name: Otegui
- first_name: Kinya
full_name: Otsu, Kinya
last_name: Otsu
- first_name: Christiane
full_name: Ott, Christiane
last_name: Ott
- first_name: Luisa
full_name: Ottobrini, Luisa
last_name: Ottobrini
- first_name: Jing Hsiung James
full_name: Ou, Jing Hsiung James
last_name: Ou
- first_name: Tiago F.
full_name: Outeiro, Tiago F.
last_name: Outeiro
- first_name: Inger
full_name: Oynebraten, Inger
last_name: Oynebraten
- first_name: Melek
full_name: Ozturk, Melek
last_name: Ozturk
- first_name: Gilles
full_name: Pagès, Gilles
last_name: Pagès
- first_name: Susanta
full_name: Pahari, Susanta
last_name: Pahari
- first_name: Marta
full_name: Pajares, Marta
last_name: Pajares
- first_name: Utpal B.
full_name: Pajvani, Utpal B.
last_name: Pajvani
- first_name: Rituraj
full_name: Pal, Rituraj
last_name: Pal
- first_name: Simona
full_name: Paladino, Simona
last_name: Paladino
- first_name: Nicolas
full_name: Pallet, Nicolas
last_name: Pallet
- first_name: Michela
full_name: Palmieri, Michela
last_name: Palmieri
- first_name: Giuseppe
full_name: Palmisano, Giuseppe
last_name: Palmisano
- first_name: Camilla
full_name: Palumbo, Camilla
last_name: Palumbo
- first_name: Francesco
full_name: Pampaloni, Francesco
last_name: Pampaloni
- first_name: Lifeng
full_name: Pan, Lifeng
last_name: Pan
- first_name: Qingjun
full_name: Pan, Qingjun
last_name: Pan
- first_name: Wenliang
full_name: Pan, Wenliang
last_name: Pan
- first_name: Xin
full_name: Pan, Xin
last_name: Pan
- first_name: Ganna
full_name: Panasyuk, Ganna
last_name: Panasyuk
- first_name: Rahul
full_name: Pandey, Rahul
last_name: Pandey
- first_name: Udai B.
full_name: Pandey, Udai B.
last_name: Pandey
- first_name: Vrajesh
full_name: Pandya, Vrajesh
last_name: Pandya
- first_name: Francesco
full_name: Paneni, Francesco
last_name: Paneni
- first_name: Shirley Y.
full_name: Pang, Shirley Y.
last_name: Pang
- first_name: Elisa
full_name: Panzarini, Elisa
last_name: Panzarini
- first_name: Daniela L.
full_name: Papademetrio, Daniela L.
last_name: Papademetrio
- first_name: Elena
full_name: Papaleo, Elena
last_name: Papaleo
- first_name: Daniel
full_name: Papinski, Daniel
last_name: Papinski
- first_name: Diana
full_name: Papp, Diana
last_name: Papp
- first_name: Eun Chan
full_name: Park, Eun Chan
last_name: Park
- first_name: Hwan Tae
full_name: Park, Hwan Tae
last_name: Park
- first_name: Ji Man
full_name: Park, Ji Man
last_name: Park
- first_name: Jong In
full_name: Park, Jong In
last_name: Park
- first_name: Joon Tae
full_name: Park, Joon Tae
last_name: Park
- first_name: Junsoo
full_name: Park, Junsoo
last_name: Park
- first_name: Sang Chul
full_name: Park, Sang Chul
last_name: Park
- first_name: Sang Youel
full_name: Park, Sang Youel
last_name: Park
- first_name: Abraham H.
full_name: Parola, Abraham H.
last_name: Parola
- first_name: Jan B.
full_name: Parys, Jan B.
last_name: Parys
- first_name: Adrien
full_name: Pasquier, Adrien
last_name: Pasquier
- first_name: Benoit
full_name: Pasquier, Benoit
last_name: Pasquier
- first_name: João F.
full_name: Passos, João F.
last_name: Passos
- first_name: Nunzia
full_name: Pastore, Nunzia
last_name: Pastore
- first_name: Hemal H.
full_name: Patel, Hemal H.
last_name: Patel
- first_name: Daniel
full_name: Patschan, Daniel
last_name: Patschan
- first_name: Sophie
full_name: Pattingre, Sophie
last_name: Pattingre
- first_name: Gustavo
full_name: Pedraza-Alva, Gustavo
last_name: Pedraza-Alva
- first_name: Jose
full_name: Pedraza-Chaverri, Jose
last_name: Pedraza-Chaverri
- first_name: Zully
full_name: Pedrozo, Zully
last_name: Pedrozo
- first_name: Gang
full_name: Pei, Gang
last_name: Pei
- first_name: Jianming
full_name: Pei, Jianming
last_name: Pei
- first_name: Hadas
full_name: Peled-Zehavi, Hadas
last_name: Peled-Zehavi
- first_name: Joaquín M.
full_name: Pellegrini, Joaquín M.
last_name: Pellegrini
- first_name: Joffrey
full_name: Pelletier, Joffrey
last_name: Pelletier
- first_name: Miguel A.
full_name: Peñalva, Miguel A.
last_name: Peñalva
- first_name: Di
full_name: Peng, Di
last_name: Peng
- first_name: Ying
full_name: Peng, Ying
last_name: Peng
- first_name: Fabio
full_name: Penna, Fabio
last_name: Penna
- first_name: Maria
full_name: Pennuto, Maria
last_name: Pennuto
- first_name: Francesca
full_name: Pentimalli, Francesca
last_name: Pentimalli
- first_name: Cláudia M.F.
full_name: Pereira, Cláudia M.F.
last_name: Pereira
- first_name: Gustavo J.S.
full_name: Pereira, Gustavo J.S.
last_name: Pereira
- first_name: Lilian C.
full_name: Pereira, Lilian C.
last_name: Pereira
- first_name: Luis
full_name: Pereira De Almeida, Luis
last_name: Pereira De Almeida
- first_name: Nirma D.
full_name: Perera, Nirma D.
last_name: Perera
- first_name: Ángel
full_name: Pérez-Lara, Ángel
last_name: Pérez-Lara
- first_name: Ana B.
full_name: Perez-Oliva, Ana B.
last_name: Perez-Oliva
- first_name: María Esther
full_name: Pérez-Pérez, María Esther
last_name: Pérez-Pérez
- first_name: Palsamy
full_name: Periyasamy, Palsamy
last_name: Periyasamy
- first_name: Andras
full_name: Perl, Andras
last_name: Perl
- first_name: Cristiana
full_name: Perrotta, Cristiana
last_name: Perrotta
- first_name: Ida
full_name: Perrotta, Ida
last_name: Perrotta
- first_name: Richard G.
full_name: Pestell, Richard G.
last_name: Pestell
- first_name: Morten
full_name: Petersen, Morten
last_name: Petersen
- first_name: Irina
full_name: Petrache, Irina
last_name: Petrache
- first_name: Goran
full_name: Petrovski, Goran
last_name: Petrovski
- first_name: Thorsten
full_name: Pfirrmann, Thorsten
last_name: Pfirrmann
- first_name: Astrid S.
full_name: Pfister, Astrid S.
last_name: Pfister
- first_name: Jennifer A.
full_name: Philips, Jennifer A.
last_name: Philips
- first_name: Huifeng
full_name: Pi, Huifeng
last_name: Pi
- first_name: Anna
full_name: Picca, Anna
last_name: Picca
- first_name: Alicia M.
full_name: Pickrell, Alicia M.
last_name: Pickrell
- first_name: Sandy
full_name: Picot, Sandy
last_name: Picot
- first_name: Giovanna M.
full_name: Pierantoni, Giovanna M.
last_name: Pierantoni
- first_name: Marina
full_name: Pierdominici, Marina
last_name: Pierdominici
- first_name: Philippe
full_name: Pierre, Philippe
last_name: Pierre
- first_name: Valérie
full_name: Pierrefite-Carle, Valérie
last_name: Pierrefite-Carle
- first_name: Karolina
full_name: Pierzynowska, Karolina
last_name: Pierzynowska
- first_name: Federico
full_name: Pietrocola, Federico
last_name: Pietrocola
- first_name: Miroslawa
full_name: Pietruczuk, Miroslawa
last_name: Pietruczuk
- first_name: Claudio
full_name: Pignata, Claudio
last_name: Pignata
- first_name: Felipe X.
full_name: Pimentel-Muiños, Felipe X.
last_name: Pimentel-Muiños
- first_name: Mario
full_name: Pinar, Mario
last_name: Pinar
- first_name: Roberta O.
full_name: Pinheiro, Roberta O.
last_name: Pinheiro
- first_name: Ronit
full_name: Pinkas-Kramarski, Ronit
last_name: Pinkas-Kramarski
- first_name: Paolo
full_name: Pinton, Paolo
last_name: Pinton
- first_name: Karolina
full_name: Pircs, Karolina
last_name: Pircs
- first_name: Sujan
full_name: Piya, Sujan
last_name: Piya
- first_name: Paola
full_name: Pizzo, Paola
last_name: Pizzo
- first_name: Theo S.
full_name: Plantinga, Theo S.
last_name: Plantinga
- first_name: Harald W.
full_name: Platta, Harald W.
last_name: Platta
- first_name: Ainhoa
full_name: Plaza-Zabala, Ainhoa
last_name: Plaza-Zabala
- first_name: Markus
full_name: Plomann, Markus
last_name: Plomann
- first_name: Egor Y.
full_name: Plotnikov, Egor Y.
last_name: Plotnikov
- first_name: Helene
full_name: Plun-Favreau, Helene
last_name: Plun-Favreau
- first_name: Ryszard
full_name: Pluta, Ryszard
last_name: Pluta
- first_name: Roger
full_name: Pocock, Roger
last_name: Pocock
- first_name: Stefanie
full_name: Pöggeler, Stefanie
last_name: Pöggeler
- first_name: Christian
full_name: Pohl, Christian
last_name: Pohl
- first_name: Marc
full_name: Poirot, Marc
last_name: Poirot
- first_name: Angelo
full_name: Poletti, Angelo
last_name: Poletti
- first_name: Marisa
full_name: Ponpuak, Marisa
last_name: Ponpuak
- first_name: Hana
full_name: Popelka, Hana
last_name: Popelka
- first_name: Blagovesta
full_name: Popova, Blagovesta
last_name: Popova
- first_name: Helena
full_name: Porta, Helena
last_name: Porta
- first_name: Soledad
full_name: Porte Alcon, Soledad
last_name: Porte Alcon
- first_name: Eliana
full_name: Portilla-Fernandez, Eliana
last_name: Portilla-Fernandez
- first_name: Martin
full_name: Post, Martin
last_name: Post
- first_name: Malia B.
full_name: Potts, Malia B.
last_name: Potts
- first_name: Joanna
full_name: Poulton, Joanna
last_name: Poulton
- first_name: Ted
full_name: Powers, Ted
last_name: Powers
- first_name: Veena
full_name: Prahlad, Veena
last_name: Prahlad
- first_name: Tomasz K.
full_name: Prajsnar, Tomasz K.
last_name: Prajsnar
- first_name: Domenico
full_name: Praticò, Domenico
last_name: Praticò
- first_name: Rosaria
full_name: Prencipe, Rosaria
last_name: Prencipe
- first_name: Muriel
full_name: Priault, Muriel
last_name: Priault
- first_name: Tassula
full_name: Proikas-Cezanne, Tassula
last_name: Proikas-Cezanne
- first_name: Vasilis J.
full_name: Promponas, Vasilis J.
last_name: Promponas
- first_name: Christopher G.
full_name: Proud, Christopher G.
last_name: Proud
- first_name: Rosa
full_name: Puertollano, Rosa
last_name: Puertollano
- first_name: Luigi
full_name: Puglielli, Luigi
last_name: Puglielli
- first_name: Thomas
full_name: Pulinilkunnil, Thomas
last_name: Pulinilkunnil
- first_name: Deepika
full_name: Puri, Deepika
last_name: Puri
- first_name: Rajat
full_name: Puri, Rajat
last_name: Puri
- first_name: Julien
full_name: Puyal, Julien
last_name: Puyal
- first_name: Xiaopeng
full_name: Qi, Xiaopeng
last_name: Qi
- first_name: Yongmei
full_name: Qi, Yongmei
last_name: Qi
- first_name: Wenbin
full_name: Qian, Wenbin
last_name: Qian
- first_name: Lei
full_name: Qiang, Lei
last_name: Qiang
- first_name: Yu
full_name: Qiu, Yu
last_name: Qiu
- first_name: Joe
full_name: Quadrilatero, Joe
last_name: Quadrilatero
- first_name: Jorge
full_name: Quarleri, Jorge
last_name: Quarleri
- first_name: Nina
full_name: Raben, Nina
last_name: Raben
- first_name: Hannah
full_name: Rabinowich, Hannah
last_name: Rabinowich
- first_name: Debora
full_name: Ragona, Debora
last_name: Ragona
- first_name: Michael J.
full_name: Ragusa, Michael J.
last_name: Ragusa
- first_name: Nader
full_name: Rahimi, Nader
last_name: Rahimi
- first_name: Marveh
full_name: Rahmati, Marveh
last_name: Rahmati
- first_name: Valeria
full_name: Raia, Valeria
last_name: Raia
- first_name: Nuno
full_name: Raimundo, Nuno
last_name: Raimundo
- first_name: Namakkal Soorappan
full_name: Rajasekaran, Namakkal Soorappan
last_name: Rajasekaran
- first_name: Sriganesh
full_name: Ramachandra Rao, Sriganesh
last_name: Ramachandra Rao
- first_name: Abdelhaq
full_name: Rami, Abdelhaq
last_name: Rami
- first_name: Ignacio
full_name: Ramírez-Pardo, Ignacio
last_name: Ramírez-Pardo
- first_name: David B.
full_name: Ramsden, David B.
last_name: Ramsden
- first_name: Felix
full_name: Randow, Felix
last_name: Randow
- first_name: Pundi N.
full_name: Rangarajan, Pundi N.
last_name: Rangarajan
- first_name: Danilo
full_name: Ranieri, Danilo
last_name: Ranieri
- first_name: Hai
full_name: Rao, Hai
last_name: Rao
- first_name: Lang
full_name: Rao, Lang
last_name: Rao
- first_name: Rekha
full_name: Rao, Rekha
last_name: Rao
- first_name: Sumit
full_name: Rathore, Sumit
last_name: Rathore
- first_name: J. Arjuna
full_name: Ratnayaka, J. Arjuna
last_name: Ratnayaka
- first_name: Edward A.
full_name: Ratovitski, Edward A.
last_name: Ratovitski
- first_name: Palaniyandi
full_name: Ravanan, Palaniyandi
last_name: Ravanan
- first_name: Gloria
full_name: Ravegnini, Gloria
last_name: Ravegnini
- first_name: Swapan K.
full_name: Ray, Swapan K.
last_name: Ray
- first_name: Babak
full_name: Razani, Babak
last_name: Razani
- first_name: Vito
full_name: Rebecca, Vito
last_name: Rebecca
- first_name: Fulvio
full_name: Reggiori, Fulvio
last_name: Reggiori
- first_name: Anne
full_name: Régnier-Vigouroux, Anne
last_name: Régnier-Vigouroux
- first_name: Andreas S.
full_name: Reichert, Andreas S.
last_name: Reichert
- first_name: David
full_name: Reigada, David
last_name: Reigada
- first_name: Jan H.
full_name: Reiling, Jan H.
last_name: Reiling
- first_name: Theo
full_name: Rein, Theo
last_name: Rein
- first_name: Siegfried
full_name: Reipert, Siegfried
last_name: Reipert
- first_name: Rokeya Sultana
full_name: Rekha, Rokeya Sultana
last_name: Rekha
- first_name: Hongmei
full_name: Ren, Hongmei
last_name: Ren
- first_name: Jun
full_name: Ren, Jun
last_name: Ren
- first_name: Weichao
full_name: Ren, Weichao
last_name: Ren
- first_name: Tristan
full_name: Renault, Tristan
last_name: Renault
- first_name: Giorgia
full_name: Renga, Giorgia
last_name: Renga
- first_name: Karen
full_name: Reue, Karen
last_name: Reue
- first_name: Kim
full_name: Rewitz, Kim
last_name: Rewitz
- first_name: Bruna
full_name: Ribeiro De Andrade Ramos, Bruna
last_name: Ribeiro De Andrade Ramos
- first_name: S. Amer
full_name: Riazuddin, S. Amer
last_name: Riazuddin
- first_name: Teresa M.
full_name: Ribeiro-Rodrigues, Teresa M.
last_name: Ribeiro-Rodrigues
- first_name: Jean Ehrland
full_name: Ricci, Jean Ehrland
last_name: Ricci
- first_name: Romeo
full_name: Ricci, Romeo
last_name: Ricci
- first_name: Victoria
full_name: Riccio, Victoria
last_name: Riccio
- first_name: Des R.
full_name: Richardson, Des R.
last_name: Richardson
- first_name: Yasuko
full_name: Rikihisa, Yasuko
last_name: Rikihisa
- first_name: Makarand V.
full_name: Risbud, Makarand V.
last_name: Risbud
- first_name: Ruth M.
full_name: Risueño, Ruth M.
last_name: Risueño
- first_name: Konstantinos
full_name: Ritis, Konstantinos
last_name: Ritis
- first_name: Salvatore
full_name: Rizza, Salvatore
last_name: Rizza
- first_name: Rosario
full_name: Rizzuto, Rosario
last_name: Rizzuto
- first_name: Helen C.
full_name: Roberts, Helen C.
last_name: Roberts
- first_name: Luke D.
full_name: Roberts, Luke D.
last_name: Roberts
- first_name: Katherine J.
full_name: Robinson, Katherine J.
last_name: Robinson
- first_name: Maria Carmela
full_name: Roccheri, Maria Carmela
last_name: Roccheri
- first_name: Stephane
full_name: Rocchi, Stephane
last_name: Rocchi
- first_name: George G.
full_name: Rodney, George G.
last_name: Rodney
- first_name: Tiago
full_name: Rodrigues, Tiago
last_name: Rodrigues
- first_name: Vagner Ramon
full_name: Rodrigues Silva, Vagner Ramon
last_name: Rodrigues Silva
- first_name: Amaia
full_name: Rodriguez, Amaia
last_name: Rodriguez
- first_name: Ruth
full_name: Rodriguez-Barrueco, Ruth
last_name: Rodriguez-Barrueco
- first_name: Nieves
full_name: Rodriguez-Henche, Nieves
last_name: Rodriguez-Henche
- first_name: Humberto
full_name: Rodriguez-Rocha, Humberto
last_name: Rodriguez-Rocha
- first_name: Jeroen
full_name: Roelofs, Jeroen
last_name: Roelofs
- first_name: Robert S.
full_name: Rogers, Robert S.
last_name: Rogers
- first_name: Vladimir V.
full_name: Rogov, Vladimir V.
last_name: Rogov
- first_name: Ana I.
full_name: Rojo, Ana I.
last_name: Rojo
- first_name: Krzysztof
full_name: Rolka, Krzysztof
last_name: Rolka
- first_name: Vanina
full_name: Romanello, Vanina
last_name: Romanello
- first_name: Luigina
full_name: Romani, Luigina
last_name: Romani
- first_name: Alessandra
full_name: Romano, Alessandra
last_name: Romano
- first_name: Patricia S.
full_name: Romano, Patricia S.
last_name: Romano
- first_name: David
full_name: Romeo-Guitart, David
last_name: Romeo-Guitart
- first_name: Luis C.
full_name: Romero, Luis C.
last_name: Romero
- first_name: Montserrat
full_name: Romero, Montserrat
last_name: Romero
- first_name: Joseph C.
full_name: Roney, Joseph C.
last_name: Roney
- first_name: Christopher
full_name: Rongo, Christopher
last_name: Rongo
- first_name: Sante
full_name: Roperto, Sante
last_name: Roperto
- first_name: Mathias T.
full_name: Rosenfeldt, Mathias T.
last_name: Rosenfeldt
- first_name: Philip
full_name: Rosenstiel, Philip
last_name: Rosenstiel
- first_name: Anne G.
full_name: Rosenwald, Anne G.
last_name: Rosenwald
- first_name: Kevin A.
full_name: Roth, Kevin A.
last_name: Roth
- first_name: Lynn
full_name: Roth, Lynn
last_name: Roth
- first_name: Steven
full_name: Roth, Steven
last_name: Roth
- first_name: Kasper M.A.
full_name: Rouschop, Kasper M.A.
last_name: Rouschop
- first_name: Benoit D.
full_name: Roussel, Benoit D.
last_name: Roussel
- first_name: Sophie
full_name: Roux, Sophie
last_name: Roux
- first_name: Patrizia
full_name: Rovere-Querini, Patrizia
last_name: Rovere-Querini
- first_name: Ajit
full_name: Roy, Ajit
last_name: Roy
- first_name: Aurore
full_name: Rozieres, Aurore
last_name: Rozieres
- first_name: Diego
full_name: Ruano, Diego
last_name: Ruano
- first_name: David C.
full_name: Rubinsztein, David C.
last_name: Rubinsztein
- first_name: Maria P.
full_name: Rubtsova, Maria P.
last_name: Rubtsova
- first_name: Klaus
full_name: Ruckdeschel, Klaus
last_name: Ruckdeschel
- first_name: Christoph
full_name: Ruckenstuhl, Christoph
last_name: Ruckenstuhl
- first_name: Emil
full_name: Rudolf, Emil
last_name: Rudolf
- first_name: Rüdiger
full_name: Rudolf, Rüdiger
last_name: Rudolf
- first_name: Alessandra
full_name: Ruggieri, Alessandra
last_name: Ruggieri
- first_name: Avnika Ashok
full_name: Ruparelia, Avnika Ashok
last_name: Ruparelia
- first_name: Paola
full_name: Rusmini, Paola
last_name: Rusmini
- first_name: Ryan R.
full_name: Russell, Ryan R.
last_name: Russell
- first_name: Gian Luigi
full_name: Russo, Gian Luigi
last_name: Russo
- first_name: Maria
full_name: Russo, Maria
last_name: Russo
- first_name: Rossella
full_name: Russo, Rossella
last_name: Russo
- first_name: Oxana O.
full_name: Ryabaya, Oxana O.
last_name: Ryabaya
- first_name: Kevin M.
full_name: Ryan, Kevin M.
last_name: Ryan
- first_name: Kwon Yul
full_name: Ryu, Kwon Yul
last_name: Ryu
- first_name: Maria
full_name: Sabater-Arcis, Maria
last_name: Sabater-Arcis
- first_name: Ulka
full_name: Sachdev, Ulka
last_name: Sachdev
- first_name: Michael
full_name: Sacher, Michael
last_name: Sacher
- first_name: Carsten
full_name: Sachse, Carsten
last_name: Sachse
- first_name: Abhishek
full_name: Sadhu, Abhishek
last_name: Sadhu
- first_name: Junichi
full_name: Sadoshima, Junichi
last_name: Sadoshima
- first_name: Nathaniel
full_name: Safren, Nathaniel
last_name: Safren
- first_name: Paul
full_name: Saftig, Paul
last_name: Saftig
- first_name: Antonia P.
full_name: Sagona, Antonia P.
last_name: Sagona
- first_name: Gaurav
full_name: Sahay, Gaurav
last_name: Sahay
- first_name: Amirhossein
full_name: Sahebkar, Amirhossein
last_name: Sahebkar
- first_name: Mustafa
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last_name: Sahin
- first_name: Ozgur
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last_name: Sahin
- first_name: Sumit
full_name: Sahni, Sumit
last_name: Sahni
- first_name: Nayuta
full_name: Saito, Nayuta
last_name: Saito
- first_name: Shigeru
full_name: Saito, Shigeru
last_name: Saito
- first_name: Tsunenori
full_name: Saito, Tsunenori
last_name: Saito
- first_name: Ryohei
full_name: Sakai, Ryohei
last_name: Sakai
- first_name: Yasuyoshi
full_name: Sakai, Yasuyoshi
last_name: Sakai
- first_name: Jun Ichi
full_name: Sakamaki, Jun Ichi
last_name: Sakamaki
- first_name: Kalle
full_name: Saksela, Kalle
last_name: Saksela
- first_name: Gloria
full_name: Salazar, Gloria
last_name: Salazar
- first_name: Anna
full_name: Salazar-Degracia, Anna
last_name: Salazar-Degracia
- first_name: Ghasem H.
full_name: Salekdeh, Ghasem H.
last_name: Salekdeh
- first_name: Ashok K.
full_name: Saluja, Ashok K.
last_name: Saluja
- first_name: Belém
full_name: Sampaio-Marques, Belém
last_name: Sampaio-Marques
- first_name: Maria Cecilia
full_name: Sanchez, Maria Cecilia
last_name: Sanchez
- first_name: Jose A.
full_name: Sanchez-Alcazar, Jose A.
last_name: Sanchez-Alcazar
- first_name: Victoria
full_name: Sanchez-Vera, Victoria
last_name: Sanchez-Vera
- first_name: Vanessa
full_name: Sancho-Shimizu, Vanessa
last_name: Sancho-Shimizu
- first_name: J. Thomas
full_name: Sanderson, J. Thomas
last_name: Sanderson
- first_name: Marco
full_name: Sandri, Marco
last_name: Sandri
- first_name: Stefano
full_name: Santaguida, Stefano
last_name: Santaguida
- first_name: Laura
full_name: Santambrogio, Laura
last_name: Santambrogio
- first_name: Magda M.
full_name: Santana, Magda M.
last_name: Santana
- first_name: Giorgio
full_name: Santoni, Giorgio
last_name: Santoni
- first_name: Alberto
full_name: Sanz, Alberto
last_name: Sanz
- first_name: Pascual
full_name: Sanz, Pascual
last_name: Sanz
- first_name: Shweta
full_name: Saran, Shweta
last_name: Saran
- first_name: Marco
full_name: Sardiello, Marco
last_name: Sardiello
- first_name: Timothy J.
full_name: Sargeant, Timothy J.
last_name: Sargeant
- first_name: Apurva
full_name: Sarin, Apurva
last_name: Sarin
- first_name: Chinmoy
full_name: Sarkar, Chinmoy
last_name: Sarkar
- first_name: Sovan
full_name: Sarkar, Sovan
last_name: Sarkar
- first_name: Maria Rosa
full_name: Sarrias, Maria Rosa
last_name: Sarrias
- first_name: Surajit
full_name: Sarkar, Surajit
last_name: Sarkar
- first_name: Dipanka Tanu
full_name: Sarmah, Dipanka Tanu
last_name: Sarmah
- first_name: Jaakko
full_name: Sarparanta, Jaakko
last_name: Sarparanta
- first_name: Aishwarya
full_name: Sathyanarayan, Aishwarya
last_name: Sathyanarayan
- first_name: Ranganayaki
full_name: Sathyanarayanan, Ranganayaki
last_name: Sathyanarayanan
- first_name: K. Matthew
full_name: Scaglione, K. Matthew
last_name: Scaglione
- first_name: Francesca
full_name: Scatozza, Francesca
last_name: Scatozza
- first_name: Liliana
full_name: Schaefer, Liliana
last_name: Schaefer
- first_name: Zachary T.
full_name: Schafer, Zachary T.
last_name: Schafer
- first_name: Ulrich E.
full_name: Schaible, Ulrich E.
last_name: Schaible
- first_name: Anthony H.V.
full_name: Schapira, Anthony H.V.
last_name: Schapira
- first_name: Michael
full_name: Scharl, Michael
last_name: Scharl
- first_name: Hermann M.
full_name: Schatzl, Hermann M.
last_name: Schatzl
- first_name: Catherine H.
full_name: Schein, Catherine H.
last_name: Schein
- first_name: Wiep
full_name: Scheper, Wiep
last_name: Scheper
- first_name: David
full_name: Scheuring, David
last_name: Scheuring
- first_name: Maria Vittoria
full_name: Schiaffino, Maria Vittoria
last_name: Schiaffino
- first_name: Monica
full_name: Schiappacassi, Monica
last_name: Schiappacassi
- first_name: Rainer
full_name: Schindl, Rainer
last_name: Schindl
- first_name: Uwe
full_name: Schlattner, Uwe
last_name: Schlattner
- first_name: Oliver
full_name: Schmidt, Oliver
last_name: Schmidt
- first_name: Roland
full_name: Schmitt, Roland
last_name: Schmitt
- first_name: Stephen D.
full_name: Schmidt, Stephen D.
last_name: Schmidt
- first_name: Ingo
full_name: Schmitz, Ingo
last_name: Schmitz
- first_name: Eran
full_name: Schmukler, Eran
last_name: Schmukler
- first_name: Anja
full_name: Schneider, Anja
last_name: Schneider
- first_name: Bianca E.
full_name: Schneider, Bianca E.
last_name: Schneider
- first_name: Romana
full_name: Schober, Romana
last_name: Schober
- first_name: Alejandra C.
full_name: Schoijet, Alejandra C.
last_name: Schoijet
- first_name: Micah B.
full_name: Schott, Micah B.
last_name: Schott
- first_name: Michael
full_name: Schramm, Michael
last_name: Schramm
- first_name: Bernd
full_name: Schröder, Bernd
last_name: Schröder
- first_name: Kai
full_name: Schuh, Kai
last_name: Schuh
- first_name: Christoph
full_name: Schüller, Christoph
last_name: Schüller
- first_name: Ryan J.
full_name: Schulze, Ryan J.
last_name: Schulze
- first_name: Lea
full_name: Schürmanns, Lea
last_name: Schürmanns
- first_name: Jens C.
full_name: Schwamborn, Jens C.
last_name: Schwamborn
- first_name: Melanie
full_name: Schwarten, Melanie
last_name: Schwarten
- first_name: Filippo
full_name: Scialo, Filippo
last_name: Scialo
- first_name: Sebastiano
full_name: Sciarretta, Sebastiano
last_name: Sciarretta
- first_name: Melanie J.
full_name: Scott, Melanie J.
last_name: Scott
- first_name: Kathleen W.
full_name: Scotto, Kathleen W.
last_name: Scotto
- first_name: A. Ivana
full_name: Scovassi, A. Ivana
last_name: Scovassi
- first_name: Andrea
full_name: Scrima, Andrea
last_name: Scrima
- first_name: Aurora
full_name: Scrivo, Aurora
last_name: Scrivo
- first_name: David
full_name: Sebastian, David
last_name: Sebastian
- first_name: Salwa
full_name: Sebti, Salwa
last_name: Sebti
- first_name: Simon
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last_name: Sedej
- first_name: Laura
full_name: Segatori, Laura
last_name: Segatori
- first_name: Nava
full_name: Segev, Nava
last_name: Segev
- first_name: Per O.
full_name: Seglen, Per O.
last_name: Seglen
- first_name: Iban
full_name: Seiliez, Iban
last_name: Seiliez
- first_name: Ekihiro
full_name: Seki, Ekihiro
last_name: Seki
- first_name: Scott B.
full_name: Selleck, Scott B.
last_name: Selleck
- first_name: Frank W.
full_name: Sellke, Frank W.
last_name: Sellke
- first_name: Joshua T.
full_name: Selsby, Joshua T.
last_name: Selsby
- first_name: Michael
full_name: Sendtner, Michael
last_name: Sendtner
- first_name: Serif
full_name: Senturk, Serif
last_name: Senturk
- first_name: Elena
full_name: Seranova, Elena
last_name: Seranova
- first_name: Consolato
full_name: Sergi, Consolato
last_name: Sergi
- first_name: Ruth
full_name: Serra-Moreno, Ruth
last_name: Serra-Moreno
- first_name: Hiromi
full_name: Sesaki, Hiromi
last_name: Sesaki
- first_name: Carmine
full_name: Settembre, Carmine
last_name: Settembre
- first_name: Subba Rao Gangi
full_name: Setty, Subba Rao Gangi
last_name: Setty
- first_name: Gianluca
full_name: Sgarbi, Gianluca
last_name: Sgarbi
- first_name: Ou
full_name: Sha, Ou
last_name: Sha
- first_name: John J.
full_name: Shacka, John J.
last_name: Shacka
- first_name: Javeed A.
full_name: Shah, Javeed A.
last_name: Shah
- first_name: Dantong
full_name: Shang, Dantong
last_name: Shang
- first_name: Changshun
full_name: Shao, Changshun
last_name: Shao
- first_name: Feng
full_name: Shao, Feng
last_name: Shao
- first_name: Soroush
full_name: Sharbati, Soroush
last_name: Sharbati
- first_name: Lisa M.
full_name: Sharkey, Lisa M.
last_name: Sharkey
- first_name: Dipali
full_name: Sharma, Dipali
last_name: Sharma
- first_name: Gaurav
full_name: Sharma, Gaurav
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- first_name: Kulbhushan
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- first_name: Pawan
full_name: Sharma, Pawan
last_name: Sharma
- first_name: Surendra
full_name: Sharma, Surendra
last_name: Sharma
- first_name: Han Ming
full_name: Shen, Han Ming
last_name: Shen
- first_name: Hongtao
full_name: Shen, Hongtao
last_name: Shen
- first_name: Jiangang
full_name: Shen, Jiangang
last_name: Shen
- first_name: Ming
full_name: Shen, Ming
last_name: Shen
- first_name: Weili
full_name: Shen, Weili
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- first_name: Zheni
full_name: Shen, Zheni
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- first_name: Rui
full_name: Sheng, Rui
last_name: Sheng
- first_name: Zhi
full_name: Sheng, Zhi
last_name: Sheng
- first_name: Zu Hang
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last_name: Sheng
- first_name: Jianjian
full_name: Shi, Jianjian
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- first_name: Xiaobing
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last_name: Shi
- first_name: Ying Hong
full_name: Shi, Ying Hong
last_name: Shi
- first_name: Kahori
full_name: Shiba-Fukushima, Kahori
last_name: Shiba-Fukushima
- first_name: Jeng Jer
full_name: Shieh, Jeng Jer
last_name: Shieh
- first_name: Yohta
full_name: Shimada, Yohta
last_name: Shimada
- first_name: Shigeomi
full_name: Shimizu, Shigeomi
last_name: Shimizu
- first_name: Makoto
full_name: Shimozawa, Makoto
last_name: Shimozawa
- first_name: Takahiro
full_name: Shintani, Takahiro
last_name: Shintani
- first_name: Christopher J.
full_name: Shoemaker, Christopher J.
last_name: Shoemaker
- first_name: Shahla
full_name: Shojaei, Shahla
last_name: Shojaei
- first_name: Ikuo
full_name: Shoji, Ikuo
last_name: Shoji
- first_name: Bhupendra V.
full_name: Shravage, Bhupendra V.
last_name: Shravage
- first_name: Viji
full_name: Shridhar, Viji
last_name: Shridhar
- first_name: Chih Wen
full_name: Shu, Chih Wen
last_name: Shu
- first_name: Hong Bing
full_name: Shu, Hong Bing
last_name: Shu
- first_name: Ke
full_name: Shui, Ke
last_name: Shui
- first_name: Arvind K.
full_name: Shukla, Arvind K.
last_name: Shukla
- first_name: Timothy E.
full_name: Shutt, Timothy E.
last_name: Shutt
- first_name: Valentina
full_name: Sica, Valentina
last_name: Sica
- first_name: Aleem
full_name: Siddiqui, Aleem
last_name: Siddiqui
- first_name: Amanda
full_name: Sierra, Amanda
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- first_name: Virginia
full_name: Sierra-Torre, Virginia
last_name: Sierra-Torre
- first_name: Santiago
full_name: Signorelli, Santiago
last_name: Signorelli
- first_name: Payel
full_name: Sil, Payel
last_name: Sil
- first_name: Bruno J.De Andrade
full_name: Silva, Bruno J.De Andrade
last_name: Silva
- first_name: Johnatas D.
full_name: Silva, Johnatas D.
last_name: Silva
- first_name: Eduardo
full_name: Silva-Pavez, Eduardo
last_name: Silva-Pavez
- first_name: Sandrine
full_name: Silvente-Poirot, Sandrine
last_name: Silvente-Poirot
- first_name: Rachel E.
full_name: Simmonds, Rachel E.
last_name: Simmonds
- first_name: Anna Katharina
full_name: Simon, Anna Katharina
last_name: Simon
- first_name: Hans Uwe
full_name: Simon, Hans Uwe
last_name: Simon
- first_name: Matias
full_name: Simons, Matias
last_name: Simons
- first_name: Anurag
full_name: Singh, Anurag
last_name: Singh
- first_name: Lalit P.
full_name: Singh, Lalit P.
last_name: Singh
- first_name: Rajat
full_name: Singh, Rajat
last_name: Singh
- first_name: Shivendra V.
full_name: Singh, Shivendra V.
last_name: Singh
- first_name: Shrawan K.
full_name: Singh, Shrawan K.
last_name: Singh
- first_name: Sudha B.
full_name: Singh, Sudha B.
last_name: Singh
- first_name: Sunaina
full_name: Singh, Sunaina
last_name: Singh
- first_name: Surinder Pal
full_name: Singh, Surinder Pal
last_name: Singh
- first_name: Debasish
full_name: Sinha, Debasish
last_name: Sinha
- first_name: Rohit Anthony
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- first_name: Sangita
full_name: Sinha, Sangita
last_name: Sinha
- first_name: Agnieszka
full_name: Sirko, Agnieszka
last_name: Sirko
- first_name: Kapil
full_name: Sirohi, Kapil
last_name: Sirohi
- first_name: Efthimios L.
full_name: Sivridis, Efthimios L.
last_name: Sivridis
- first_name: Panagiotis
full_name: Skendros, Panagiotis
last_name: Skendros
- first_name: Aleksandra
full_name: Skirycz, Aleksandra
last_name: Skirycz
- first_name: Iva
full_name: Slaninová, Iva
last_name: Slaninová
- first_name: Soraya S.
full_name: Smaili, Soraya S.
last_name: Smaili
- first_name: Andrei
full_name: Smertenko, Andrei
last_name: Smertenko
- first_name: Matthew D.
full_name: Smith, Matthew D.
last_name: Smith
- first_name: Stefaan J.
full_name: Soenen, Stefaan J.
last_name: Soenen
- first_name: Eun Jung
full_name: Sohn, Eun Jung
last_name: Sohn
- first_name: Sophia P.M.
full_name: Sok, Sophia P.M.
last_name: Sok
- first_name: Giancarlo
full_name: Solaini, Giancarlo
last_name: Solaini
- first_name: Thierry
full_name: Soldati, Thierry
last_name: Soldati
- first_name: Scott A.
full_name: Soleimanpour, Scott A.
last_name: Soleimanpour
- first_name: Rosa M.
full_name: Soler, Rosa M.
last_name: Soler
- first_name: Alexei
full_name: Solovchenko, Alexei
last_name: Solovchenko
- first_name: Jason A.
full_name: Somarelli, Jason A.
last_name: Somarelli
- first_name: Avinash
full_name: Sonawane, Avinash
last_name: Sonawane
- first_name: Fuyong
full_name: Song, Fuyong
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- first_name: Hyun Kyu
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- first_name: Ju Xian
full_name: Song, Ju Xian
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- first_name: Kunhua
full_name: Song, Kunhua
last_name: Song
- first_name: Zhiyin
full_name: Song, Zhiyin
last_name: Song
- first_name: Leandro R.
full_name: Soria, Leandro R.
last_name: Soria
- first_name: Maurizio
full_name: Sorice, Maurizio
last_name: Sorice
- first_name: Alexander A.
full_name: Soukas, Alexander A.
last_name: Soukas
- first_name: Sandra Fausia
full_name: Soukup, Sandra Fausia
last_name: Soukup
- first_name: Diana
full_name: Sousa, Diana
last_name: Sousa
- first_name: Nadia
full_name: Sousa, Nadia
last_name: Sousa
- first_name: Paul A.
full_name: Spagnuolo, Paul A.
last_name: Spagnuolo
- first_name: Stephen A.
full_name: Spector, Stephen A.
last_name: Spector
- first_name: M. M.
full_name: Srinivas Bharath, M. M.
last_name: Srinivas Bharath
- first_name: Daret
full_name: St. Clair, Daret
last_name: St. Clair
- first_name: Venturina
full_name: Stagni, Venturina
last_name: Stagni
- first_name: Leopoldo
full_name: Staiano, Leopoldo
last_name: Staiano
- first_name: Clint A.
full_name: Stalnecker, Clint A.
last_name: Stalnecker
- first_name: Metodi V.
full_name: Stankov, Metodi V.
last_name: Stankov
- first_name: Peter B.
full_name: Stathopulos, Peter B.
last_name: Stathopulos
- first_name: Katja
full_name: Stefan, Katja
last_name: Stefan
- first_name: Sven Marcel
full_name: Stefan, Sven Marcel
last_name: Stefan
- first_name: Leonidas
full_name: Stefanis, Leonidas
last_name: Stefanis
- first_name: Joan S.
full_name: Steffan, Joan S.
last_name: Steffan
- first_name: Alexander
full_name: Steinkasserer, Alexander
last_name: Steinkasserer
- first_name: Harald
full_name: Stenmark, Harald
last_name: Stenmark
- first_name: Jared
full_name: Sterneckert, Jared
last_name: Sterneckert
- first_name: Craig
full_name: Stevens, Craig
last_name: Stevens
- first_name: Veronika
full_name: Stoka, Veronika
last_name: Stoka
- first_name: Stephan
full_name: Storch, Stephan
last_name: Storch
- first_name: Björn
full_name: Stork, Björn
last_name: Stork
- first_name: Flavie
full_name: Strappazzon, Flavie
last_name: Strappazzon
- first_name: Anne Marie
full_name: Strohecker, Anne Marie
last_name: Strohecker
- first_name: Dwayne G.
full_name: Stupack, Dwayne G.
last_name: Stupack
- first_name: Huanxing
full_name: Su, Huanxing
last_name: Su
- first_name: Ling Yan
full_name: Su, Ling Yan
last_name: Su
- first_name: Longxiang
full_name: Su, Longxiang
last_name: Su
- first_name: Ana M.
full_name: Suarez-Fontes, Ana M.
last_name: Suarez-Fontes
- first_name: Carlos S.
full_name: Subauste, Carlos S.
last_name: Subauste
- first_name: Selvakumar
full_name: Subbian, Selvakumar
last_name: Subbian
- first_name: Paula V.
full_name: Subirada, Paula V.
last_name: Subirada
- first_name: Ganapasam
full_name: Sudhandiran, Ganapasam
last_name: Sudhandiran
- first_name: Carolyn M.
full_name: Sue, Carolyn M.
last_name: Sue
- first_name: Xinbing
full_name: Sui, Xinbing
last_name: Sui
- first_name: Corey
full_name: Summers, Corey
last_name: Summers
- first_name: Guangchao
full_name: Sun, Guangchao
last_name: Sun
- first_name: Jun
full_name: Sun, Jun
last_name: Sun
- first_name: Kang
full_name: Sun, Kang
last_name: Sun
- first_name: Meng Xiang
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last_name: Sun
- first_name: Qiming
full_name: Sun, Qiming
last_name: Sun
- first_name: Yi
full_name: Sun, Yi
last_name: Sun
- first_name: Zhongjie
full_name: Sun, Zhongjie
last_name: Sun
- first_name: Karen K.S.
full_name: Sunahara, Karen K.S.
last_name: Sunahara
- first_name: Eva
full_name: Sundberg, Eva
last_name: Sundberg
- first_name: Katalin
full_name: Susztak, Katalin
last_name: Susztak
- first_name: Peter
full_name: Sutovsky, Peter
last_name: Sutovsky
- first_name: Hidekazu
full_name: Suzuki, Hidekazu
last_name: Suzuki
- first_name: Gary
full_name: Sweeney, Gary
last_name: Sweeney
- first_name: J. David
full_name: Symons, J. David
last_name: Symons
- first_name: Stephen Cho Wing
full_name: Sze, Stephen Cho Wing
last_name: Sze
- first_name: Nathaniel J.
full_name: Szewczyk, Nathaniel J.
last_name: Szewczyk
- first_name: Anna
full_name: Tabęcka-Łonczynska, Anna
last_name: Tabęcka-Łonczynska
- first_name: Claudio
full_name: Tabolacci, Claudio
last_name: Tabolacci
- first_name: Frank
full_name: Tacke, Frank
last_name: Tacke
- first_name: Heinrich
full_name: Taegtmeyer, Heinrich
last_name: Taegtmeyer
- first_name: Marco
full_name: Tafani, Marco
last_name: Tafani
- first_name: Mitsuo
full_name: Tagaya, Mitsuo
last_name: Tagaya
- first_name: Haoran
full_name: Tai, Haoran
last_name: Tai
- first_name: Stephen W.G.
full_name: Tait, Stephen W.G.
last_name: Tait
- first_name: Yoshinori
full_name: Takahashi, Yoshinori
last_name: Takahashi
- first_name: Szabolcs
full_name: Takats, Szabolcs
last_name: Takats
- first_name: Priti
full_name: Talwar, Priti
last_name: Talwar
- first_name: Chit
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last_name: Tam
- first_name: Shing Yau
full_name: Tam, Shing Yau
last_name: Tam
- first_name: Davide
full_name: Tampellini, Davide
last_name: Tampellini
- first_name: Atsushi
full_name: Tamura, Atsushi
last_name: Tamura
- first_name: Chong Teik
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last_name: Tan
- first_name: Eng King
full_name: Tan, Eng King
last_name: Tan
- first_name: Ya Qin
full_name: Tan, Ya Qin
last_name: Tan
- first_name: Masaki
full_name: Tanaka, Masaki
last_name: Tanaka
- first_name: Motomasa
full_name: Tanaka, Motomasa
last_name: Tanaka
- first_name: Daolin
full_name: Tang, Daolin
last_name: Tang
- first_name: Jingfeng
full_name: Tang, Jingfeng
last_name: Tang
- first_name: Tie Shan
full_name: Tang, Tie Shan
last_name: Tang
- first_name: Isei
full_name: Tanida, Isei
last_name: Tanida
- first_name: Zhipeng
full_name: Tao, Zhipeng
last_name: Tao
- first_name: Mohammed
full_name: Taouis, Mohammed
last_name: Taouis
- first_name: Lars
full_name: Tatenhorst, Lars
last_name: Tatenhorst
- first_name: Nektarios
full_name: Tavernarakis, Nektarios
last_name: Tavernarakis
- first_name: Allen
full_name: Taylor, Allen
last_name: Taylor
- first_name: Gregory A.
full_name: Taylor, Gregory A.
last_name: Taylor
- first_name: Joan M.
full_name: Taylor, Joan M.
last_name: Taylor
- first_name: Elena
full_name: Tchetina, Elena
last_name: Tchetina
- first_name: Andrew R.
full_name: Tee, Andrew R.
last_name: Tee
- first_name: Irmgard
full_name: Tegeder, Irmgard
last_name: Tegeder
- first_name: David
full_name: Teis, David
last_name: Teis
- first_name: Natercia
full_name: Teixeira, Natercia
last_name: Teixeira
- first_name: Fatima
full_name: Teixeira-Clerc, Fatima
last_name: Teixeira-Clerc
- first_name: Kumsal A.
full_name: Tekirdag, Kumsal A.
last_name: Tekirdag
- first_name: Tewin
full_name: Tencomnao, Tewin
last_name: Tencomnao
- first_name: Sandra
full_name: Tenreiro, Sandra
last_name: Tenreiro
- first_name: Alexei V.
full_name: Tepikin, Alexei V.
last_name: Tepikin
- first_name: Pilar S.
full_name: Testillano, Pilar S.
last_name: Testillano
- first_name: Gianluca
full_name: Tettamanti, Gianluca
last_name: Tettamanti
- first_name: Pierre Louis
full_name: Tharaux, Pierre Louis
last_name: Tharaux
- first_name: Kathrin
full_name: Thedieck, Kathrin
last_name: Thedieck
- first_name: Arvind A.
full_name: Thekkinghat, Arvind A.
last_name: Thekkinghat
- first_name: Stefano
full_name: Thellung, Stefano
last_name: Thellung
- first_name: Josephine W.
full_name: Thinwa, Josephine W.
last_name: Thinwa
- first_name: V. P.
full_name: Thirumalaikumar, V. P.
last_name: Thirumalaikumar
- first_name: Sufi Mary
full_name: Thomas, Sufi Mary
last_name: Thomas
- first_name: Paul G.
full_name: Thomes, Paul G.
last_name: Thomes
- first_name: Andrew
full_name: Thorburn, Andrew
last_name: Thorburn
- first_name: Lipi
full_name: Thukral, Lipi
last_name: Thukral
- first_name: Thomas
full_name: Thum, Thomas
last_name: Thum
- first_name: Michael
full_name: Thumm, Michael
last_name: Thumm
- first_name: Ling
full_name: Tian, Ling
last_name: Tian
- first_name: Ales
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last_name: Tichy
- first_name: Andreas
full_name: Till, Andreas
last_name: Till
- first_name: Vincent
full_name: Timmerman, Vincent
last_name: Timmerman
- first_name: Vladimir I.
full_name: Titorenko, Vladimir I.
last_name: Titorenko
- first_name: Sokol V.
full_name: Todi, Sokol V.
last_name: Todi
- first_name: Krassimira
full_name: Todorova, Krassimira
last_name: Todorova
- first_name: Janne M.
full_name: Toivonen, Janne M.
last_name: Toivonen
- first_name: Luana
full_name: Tomaipitinca, Luana
last_name: Tomaipitinca
- first_name: Dhanendra
full_name: Tomar, Dhanendra
last_name: Tomar
- first_name: Cristina
full_name: Tomas-Zapico, Cristina
last_name: Tomas-Zapico
- first_name: Sergej
full_name: Tomić, Sergej
last_name: Tomić
- first_name: Benjamin Chun Kit
full_name: Tong, Benjamin Chun Kit
last_name: Tong
- first_name: Chao
full_name: Tong, Chao
last_name: Tong
- first_name: Xin
full_name: Tong, Xin
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last_name: Tong
- first_name: Sharon A.
full_name: Tooze, Sharon A.
last_name: Tooze
- first_name: Maria L.
full_name: Torgersen, Maria L.
last_name: Torgersen
- first_name: Satoru
full_name: Torii, Satoru
last_name: Torii
- first_name: Liliana
full_name: Torres-López, Liliana
last_name: Torres-López
- first_name: Alicia
full_name: Torriglia, Alicia
last_name: Torriglia
- first_name: Christina G.
full_name: Towers, Christina G.
last_name: Towers
- first_name: Roberto
full_name: Towns, Roberto
last_name: Towns
- first_name: Shinya
full_name: Toyokuni, Shinya
last_name: Toyokuni
- first_name: Vladimir
full_name: Trajkovic, Vladimir
last_name: Trajkovic
- first_name: Donatella
full_name: Tramontano, Donatella
last_name: Tramontano
- first_name: Quynh Giao
full_name: Tran, Quynh Giao
last_name: Tran
- first_name: Leonardo H.
full_name: Travassos, Leonardo H.
last_name: Travassos
- first_name: Charles B.
full_name: Trelford, Charles B.
last_name: Trelford
- first_name: Shirley
full_name: Tremel, Shirley
last_name: Tremel
- first_name: Ioannis P.
full_name: Trougakos, Ioannis P.
last_name: Trougakos
- first_name: Betty P.
full_name: Tsao, Betty P.
last_name: Tsao
- first_name: Mario P.
full_name: Tschan, Mario P.
last_name: Tschan
- first_name: Hung Fat
full_name: Tse, Hung Fat
last_name: Tse
- first_name: Tak Fu
full_name: Tse, Tak Fu
last_name: Tse
- first_name: Hitoshi
full_name: Tsugawa, Hitoshi
last_name: Tsugawa
- first_name: Andrey S.
full_name: Tsvetkov, Andrey S.
last_name: Tsvetkov
- first_name: David A.
full_name: Tumbarello, David A.
last_name: Tumbarello
- first_name: Yasin
full_name: Tumtas, Yasin
last_name: Tumtas
- first_name: María J.
full_name: Tuñón, María J.
last_name: Tuñón
- first_name: Sandra
full_name: Turcotte, Sandra
last_name: Turcotte
- first_name: Boris
full_name: Turk, Boris
last_name: Turk
- first_name: Vito
full_name: Turk, Vito
last_name: Turk
- first_name: Bradley J.
full_name: Turner, Bradley J.
last_name: Turner
- first_name: Richard I.
full_name: Tuxworth, Richard I.
last_name: Tuxworth
- first_name: Jessica K.
full_name: Tyler, Jessica K.
last_name: Tyler
- first_name: Elena V.
full_name: Tyutereva, Elena V.
last_name: Tyutereva
- first_name: Yasuo
full_name: Uchiyama, Yasuo
last_name: Uchiyama
- first_name: Aslihan
full_name: Ugun-Klusek, Aslihan
last_name: Ugun-Klusek
- first_name: Holm H.
full_name: Uhlig, Holm H.
last_name: Uhlig
- first_name: Marzena
full_name: Ułamek-Kozioł, Marzena
last_name: Ułamek-Kozioł
- first_name: Ilya V.
full_name: Ulasov, Ilya V.
last_name: Ulasov
- first_name: Midori
full_name: Umekawa, Midori
last_name: Umekawa
- first_name: Christian
full_name: Ungermann, Christian
last_name: Ungermann
- first_name: Rei
full_name: Unno, Rei
last_name: Unno
- first_name: Sylvie
full_name: Urbe, Sylvie
last_name: Urbe
- first_name: Elisabet
full_name: Uribe-Carretero, Elisabet
last_name: Uribe-Carretero
- first_name: Suayib
full_name: Üstün, Suayib
last_name: Üstün
- first_name: Vladimir N.
full_name: Uversky, Vladimir N.
last_name: Uversky
- first_name: Thomas
full_name: Vaccari, Thomas
last_name: Vaccari
- first_name: Maria I.
full_name: Vaccaro, Maria I.
last_name: Vaccaro
- first_name: Björn F.
full_name: Vahsen, Björn F.
last_name: Vahsen
- first_name: Helin
full_name: Vakifahmetoglu-Norberg, Helin
last_name: Vakifahmetoglu-Norberg
- first_name: Rut
full_name: Valdor, Rut
last_name: Valdor
- first_name: Maria J.
full_name: Valente, Maria J.
last_name: Valente
- first_name: Ayelén
full_name: Valko, Ayelén
last_name: Valko
- first_name: Richard B.
full_name: Vallee, Richard B.
last_name: Vallee
- first_name: Angela M.
full_name: Valverde, Angela M.
last_name: Valverde
- first_name: Greet
full_name: Van Den Berghe, Greet
last_name: Van Den Berghe
- first_name: Stijn
full_name: Van Der Veen, Stijn
last_name: Van Der Veen
- first_name: Luc
full_name: Van Kaer, Luc
last_name: Van Kaer
- first_name: Jorg
full_name: Van Loosdregt, Jorg
last_name: Van Loosdregt
- first_name: Sjoerd J.L.
full_name: Van Wijk, Sjoerd J.L.
last_name: Van Wijk
- first_name: Wim
full_name: Vandenberghe, Wim
last_name: Vandenberghe
- first_name: Ilse
full_name: Vanhorebeek, Ilse
last_name: Vanhorebeek
- first_name: Marcos A.
full_name: Vannier-Santos, Marcos A.
last_name: Vannier-Santos
- first_name: Nicola
full_name: Vannini, Nicola
last_name: Vannini
- first_name: M. Cristina
full_name: Vanrell, M. Cristina
last_name: Vanrell
- first_name: Chiara
full_name: Vantaggiato, Chiara
last_name: Vantaggiato
- first_name: Gabriele
full_name: Varano, Gabriele
last_name: Varano
- first_name: Isabel
full_name: Varela-Nieto, Isabel
last_name: Varela-Nieto
- first_name: Máté
full_name: Varga, Máté
last_name: Varga
- first_name: M. Helena
full_name: Vasconcelos, M. Helena
last_name: Vasconcelos
- first_name: Somya
full_name: Vats, Somya
last_name: Vats
- first_name: Demetrios G.
full_name: Vavvas, Demetrios G.
last_name: Vavvas
- first_name: Ignacio
full_name: Vega-Naredo, Ignacio
last_name: Vega-Naredo
- first_name: Silvia
full_name: Vega-Rubin-De-Celis, Silvia
last_name: Vega-Rubin-De-Celis
- first_name: Guillermo
full_name: Velasco, Guillermo
last_name: Velasco
- first_name: Ariadna P.
full_name: Velázquez, Ariadna P.
last_name: Velázquez
- first_name: Tibor
full_name: Vellai, Tibor
last_name: Vellai
- first_name: Edo
full_name: Vellenga, Edo
last_name: Vellenga
- first_name: Francesca
full_name: Velotti, Francesca
last_name: Velotti
- first_name: Mireille
full_name: Verdier, Mireille
last_name: Verdier
- first_name: Panayotis
full_name: Verginis, Panayotis
last_name: Verginis
- first_name: Isabelle
full_name: Vergne, Isabelle
last_name: Vergne
- first_name: Paul
full_name: Verkade, Paul
last_name: Verkade
- first_name: Manish
full_name: Verma, Manish
last_name: Verma
- first_name: Patrik
full_name: Verstreken, Patrik
last_name: Verstreken
- first_name: Tim
full_name: Vervliet, Tim
last_name: Vervliet
- first_name: Jörg
full_name: Vervoorts, Jörg
last_name: Vervoorts
- first_name: Alexandre T.
full_name: Vessoni, Alexandre T.
last_name: Vessoni
- first_name: Victor M.
full_name: Victor, Victor M.
last_name: Victor
- first_name: Michel
full_name: Vidal, Michel
last_name: Vidal
- first_name: Chiara
full_name: Vidoni, Chiara
last_name: Vidoni
- first_name: Otilia V.
full_name: Vieira, Otilia V.
last_name: Vieira
- first_name: Richard D.
full_name: Vierstra, Richard D.
last_name: Vierstra
- first_name: Sonia
full_name: Viganó, Sonia
last_name: Viganó
- first_name: Helena
full_name: Vihinen, Helena
last_name: Vihinen
- first_name: Vinoy
full_name: Vijayan, Vinoy
last_name: Vijayan
- first_name: Miquel
full_name: Vila, Miquel
last_name: Vila
- first_name: Marçal
full_name: Vilar, Marçal
last_name: Vilar
- first_name: José M.
full_name: Villalba, José M.
last_name: Villalba
- first_name: Antonio
full_name: Villalobo, Antonio
last_name: Villalobo
- first_name: Beatriz
full_name: Villarejo-Zori, Beatriz
last_name: Villarejo-Zori
- first_name: Francesc
full_name: Villarroya, Francesc
last_name: Villarroya
- first_name: Joan
full_name: Villarroya, Joan
last_name: Villarroya
- first_name: Olivier
full_name: Vincent, Olivier
last_name: Vincent
- first_name: Cecile
full_name: Vindis, Cecile
last_name: Vindis
- first_name: Christophe
full_name: Viret, Christophe
last_name: Viret
- first_name: Maria Teresa
full_name: Viscomi, Maria Teresa
last_name: Viscomi
- first_name: Dora
full_name: Visnjic, Dora
last_name: Visnjic
- first_name: Ilio
full_name: Vitale, Ilio
last_name: Vitale
- first_name: David J.
full_name: Vocadlo, David J.
last_name: Vocadlo
- first_name: Olga V.
full_name: Voitsekhovskaja, Olga V.
last_name: Voitsekhovskaja
- first_name: Cinzia
full_name: Volonté, Cinzia
last_name: Volonté
- first_name: Mattia
full_name: Volta, Mattia
last_name: Volta
- first_name: Marta
full_name: Vomero, Marta
last_name: Vomero
- first_name: Clarissa
full_name: Von Haefen, Clarissa
last_name: Von Haefen
- first_name: Marc A.
full_name: Vooijs, Marc A.
last_name: Vooijs
- first_name: Wolfgang
full_name: Voos, Wolfgang
last_name: Voos
- first_name: Ljubica
full_name: Vucicevic, Ljubica
last_name: Vucicevic
- first_name: Richard
full_name: Wade-Martins, Richard
last_name: Wade-Martins
- first_name: Satoshi
full_name: Waguri, Satoshi
last_name: Waguri
- first_name: Kenrick A.
full_name: Waite, Kenrick A.
last_name: Waite
- first_name: Shuji
full_name: Wakatsuki, Shuji
last_name: Wakatsuki
- first_name: David W.
full_name: Walker, David W.
last_name: Walker
- first_name: Mark J.
full_name: Walker, Mark J.
last_name: Walker
- first_name: Simon A.
full_name: Walker, Simon A.
last_name: Walker
- first_name: Jochen
full_name: Walter, Jochen
last_name: Walter
- first_name: Francisco G.
full_name: Wandosell, Francisco G.
last_name: Wandosell
- first_name: Bo
full_name: Wang, Bo
last_name: Wang
- first_name: Chao Yung
full_name: Wang, Chao Yung
last_name: Wang
- first_name: Chen
full_name: Wang, Chen
last_name: Wang
- first_name: Chenran
full_name: Wang, Chenran
last_name: Wang
- first_name: Chenwei
full_name: Wang, Chenwei
last_name: Wang
- first_name: Cun Yu
full_name: Wang, Cun Yu
last_name: Wang
- first_name: Dong
full_name: Wang, Dong
last_name: Wang
- first_name: Fangyang
full_name: Wang, Fangyang
last_name: Wang
- first_name: Feng
full_name: Wang, Feng
last_name: Wang
- first_name: Fengming
full_name: Wang, Fengming
last_name: Wang
- first_name: Guansong
full_name: Wang, Guansong
last_name: Wang
- first_name: Han
full_name: Wang, Han
last_name: Wang
- first_name: Hao
full_name: Wang, Hao
last_name: Wang
- first_name: Hexiang
full_name: Wang, Hexiang
last_name: Wang
- first_name: Hong Gang
full_name: Wang, Hong Gang
last_name: Wang
- first_name: Jianrong
full_name: Wang, Jianrong
last_name: Wang
- first_name: Jigang
full_name: Wang, Jigang
last_name: Wang
- first_name: Jiou
full_name: Wang, Jiou
last_name: Wang
- first_name: Jundong
full_name: Wang, Jundong
last_name: Wang
- first_name: Kui
full_name: Wang, Kui
last_name: Wang
- first_name: Lianrong
full_name: Wang, Lianrong
last_name: Wang
- first_name: Liming
full_name: Wang, Liming
last_name: Wang
- first_name: Maggie Haitian
full_name: Wang, Maggie Haitian
last_name: Wang
- first_name: Meiqing
full_name: Wang, Meiqing
last_name: Wang
- first_name: Nanbu
full_name: Wang, Nanbu
last_name: Wang
- first_name: Pengwei
full_name: Wang, Pengwei
last_name: Wang
- first_name: Peipei
full_name: Wang, Peipei
last_name: Wang
- first_name: Ping
full_name: Wang, Ping
last_name: Wang
- first_name: Ping
full_name: Wang, Ping
last_name: Wang
- first_name: Qing Jun
full_name: Wang, Qing Jun
last_name: Wang
- first_name: Qing
full_name: Wang, Qing
last_name: Wang
- first_name: Qing Kenneth
full_name: Wang, Qing Kenneth
last_name: Wang
- first_name: Qiong A.
full_name: Wang, Qiong A.
last_name: Wang
- first_name: Wen Tao
full_name: Wang, Wen Tao
last_name: Wang
- first_name: Wuyang
full_name: Wang, Wuyang
last_name: Wang
- first_name: Xinnan
full_name: Wang, Xinnan
last_name: Wang
- first_name: Xuejun
full_name: Wang, Xuejun
last_name: Wang
- first_name: Yan
full_name: Wang, Yan
last_name: Wang
- first_name: Yanchang
full_name: Wang, Yanchang
last_name: Wang
- first_name: Yanzhuang
full_name: Wang, Yanzhuang
last_name: Wang
- first_name: Yen Yun
full_name: Wang, Yen Yun
last_name: Wang
- first_name: Yihua
full_name: Wang, Yihua
last_name: Wang
- first_name: Yipeng
full_name: Wang, Yipeng
last_name: Wang
- first_name: Yu
full_name: Wang, Yu
last_name: Wang
- first_name: Yuqi
full_name: Wang, Yuqi
last_name: Wang
- first_name: Zhe
full_name: Wang, Zhe
last_name: Wang
- first_name: Zhenyu
full_name: Wang, Zhenyu
last_name: Wang
- first_name: Zhouguang
full_name: Wang, Zhouguang
last_name: Wang
- first_name: Gary
full_name: Warnes, Gary
last_name: Warnes
- first_name: Verena
full_name: Warnsmann, Verena
last_name: Warnsmann
- first_name: Hirotaka
full_name: Watada, Hirotaka
last_name: Watada
- first_name: Eizo
full_name: Watanabe, Eizo
last_name: Watanabe
- first_name: Maxinne
full_name: Watchon, Maxinne
last_name: Watchon
- first_name: Anna
full_name: Wawrzyńska, Anna
last_name: Wawrzyńska
- first_name: Timothy E.
full_name: Weaver, Timothy E.
last_name: Weaver
- first_name: Grzegorz
full_name: Wegrzyn, Grzegorz
last_name: Wegrzyn
- first_name: Ann M.
full_name: Wehman, Ann M.
last_name: Wehman
- first_name: Huafeng
full_name: Wei, Huafeng
last_name: Wei
- first_name: Lei
full_name: Wei, Lei
last_name: Wei
- first_name: Taotao
full_name: Wei, Taotao
last_name: Wei
- first_name: Yongjie
full_name: Wei, Yongjie
last_name: Wei
- first_name: Oliver H.
full_name: Weiergräber, Oliver H.
last_name: Weiergräber
- first_name: Conrad C.
full_name: Weihl, Conrad C.
last_name: Weihl
- first_name: Günther
full_name: Weindl, Günther
last_name: Weindl
- first_name: Ralf
full_name: Weiskirchen, Ralf
last_name: Weiskirchen
- first_name: Alan
full_name: Wells, Alan
last_name: Wells
- first_name: Runxia H.
full_name: Wen, Runxia H.
last_name: Wen
- first_name: Xin
full_name: Wen, Xin
last_name: Wen
- first_name: Antonia
full_name: Werner, Antonia
last_name: Werner
- first_name: Beatrice
full_name: Weykopf, Beatrice
last_name: Weykopf
- first_name: Sally P.
full_name: Wheatley, Sally P.
last_name: Wheatley
- first_name: J. Lindsay
full_name: Whitton, J. Lindsay
last_name: Whitton
- first_name: Alexander J.
full_name: Whitworth, Alexander J.
last_name: Whitworth
- first_name: Katarzyna
full_name: Wiktorska, Katarzyna
last_name: Wiktorska
- first_name: Manon E.
full_name: Wildenberg, Manon E.
last_name: Wildenberg
- first_name: Tom
full_name: Wileman, Tom
last_name: Wileman
- first_name: Simon
full_name: Wilkinson, Simon
last_name: Wilkinson
- first_name: Dieter
full_name: Willbold, Dieter
last_name: Willbold
- first_name: Brett
full_name: Williams, Brett
last_name: Williams
- first_name: Robin S.B.
full_name: Williams, Robin S.B.
last_name: Williams
- first_name: Roger L.
full_name: Williams, Roger L.
last_name: Williams
- first_name: Peter R.
full_name: Williamson, Peter R.
last_name: Williamson
- first_name: Richard A.
full_name: Wilson, Richard A.
last_name: Wilson
- first_name: Beate
full_name: Winner, Beate
last_name: Winner
- first_name: Nathaniel J.
full_name: Winsor, Nathaniel J.
last_name: Winsor
- first_name: Steven S.
full_name: Witkin, Steven S.
last_name: Witkin
- first_name: Harald
full_name: Wodrich, Harald
last_name: Wodrich
- first_name: Ute
full_name: Woehlbier, Ute
last_name: Woehlbier
- first_name: Thomas
full_name: Wollert, Thomas
last_name: Wollert
- first_name: Esther
full_name: Wong, Esther
last_name: Wong
- first_name: Jack Ho
full_name: Wong, Jack Ho
last_name: Wong
- first_name: Richard W.
full_name: Wong, Richard W.
last_name: Wong
- first_name: Vincent Kam Wai
full_name: Wong, Vincent Kam Wai
last_name: Wong
- first_name: W. Wei Lynn
full_name: Wong, W. Wei Lynn
last_name: Wong
- first_name: An Guo
full_name: Wu, An Guo
last_name: Wu
- first_name: Chengbiao
full_name: Wu, Chengbiao
last_name: Wu
- first_name: Jian
full_name: Wu, Jian
last_name: Wu
- first_name: Junfang
full_name: Wu, Junfang
last_name: Wu
- first_name: Kenneth K.
full_name: Wu, Kenneth K.
last_name: Wu
- first_name: Min
full_name: Wu, Min
last_name: Wu
- first_name: Shan Ying
full_name: Wu, Shan Ying
last_name: Wu
- first_name: Shengzhou
full_name: Wu, Shengzhou
last_name: Wu
- first_name: Shu Yan
full_name: Wu, Shu Yan
last_name: Wu
- first_name: Shufang
full_name: Wu, Shufang
last_name: Wu
- first_name: William K.K.
full_name: Wu, William K.K.
last_name: Wu
- first_name: Xiaohong
full_name: Wu, Xiaohong
last_name: Wu
- first_name: Xiaoqing
full_name: Wu, Xiaoqing
last_name: Wu
- first_name: Yao Wen
full_name: Wu, Yao Wen
last_name: Wu
- first_name: Yihua
full_name: Wu, Yihua
last_name: Wu
- first_name: Ramnik J.
full_name: Xavier, Ramnik J.
last_name: Xavier
- first_name: Hongguang
full_name: Xia, Hongguang
last_name: Xia
- first_name: Lixin
full_name: Xia, Lixin
last_name: Xia
- first_name: Zhengyuan
full_name: Xia, Zhengyuan
last_name: Xia
- first_name: Ge
full_name: Xiang, Ge
last_name: Xiang
- first_name: Jin
full_name: Xiang, Jin
last_name: Xiang
- first_name: Mingliang
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last_name: Xiang
- first_name: Wei
full_name: Xiang, Wei
last_name: Xiang
- first_name: Bin
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last_name: Xiao
- first_name: Guozhi
full_name: Xiao, Guozhi
last_name: Xiao
- first_name: Hengyi
full_name: Xiao, Hengyi
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- first_name: Hong Tao
full_name: Xiao, Hong Tao
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- first_name: Jian
full_name: Xiao, Jian
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- first_name: Lan
full_name: Xiao, Lan
last_name: Xiao
- first_name: Shi
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- first_name: Yin
full_name: Xiao, Yin
last_name: Xiao
- first_name: Baoming
full_name: Xie, Baoming
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- first_name: Chuan Ming
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last_name: Xie
- first_name: Min
full_name: Xie, Min
last_name: Xie
- first_name: Yuxiang
full_name: Xie, Yuxiang
last_name: Xie
- first_name: Zhiping
full_name: Xie, Zhiping
last_name: Xie
- first_name: Zhonglin
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last_name: Xie
- first_name: Maria
full_name: Xilouri, Maria
last_name: Xilouri
- first_name: Congfeng
full_name: Xu, Congfeng
last_name: Xu
- first_name: En
full_name: Xu, En
last_name: Xu
- first_name: Haoxing
full_name: Xu, Haoxing
last_name: Xu
- first_name: Jing
full_name: Xu, Jing
last_name: Xu
- first_name: Jin Rong
full_name: Xu, Jin Rong
last_name: Xu
- first_name: Liang
full_name: Xu, Liang
last_name: Xu
- first_name: Wen Wen
full_name: Xu, Wen Wen
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- first_name: Xiulong
full_name: Xu, Xiulong
last_name: Xu
- first_name: Yu
full_name: Xue, Yu
last_name: Xue
- first_name: Sokhna M.S.
full_name: Yakhine-Diop, Sokhna M.S.
last_name: Yakhine-Diop
- first_name: Masamitsu
full_name: Yamaguchi, Masamitsu
last_name: Yamaguchi
- first_name: Osamu
full_name: Yamaguchi, Osamu
last_name: Yamaguchi
- first_name: Ai
full_name: Yamamoto, Ai
last_name: Yamamoto
- first_name: Shunhei
full_name: Yamashina, Shunhei
last_name: Yamashina
- first_name: Shengmin
full_name: Yan, Shengmin
last_name: Yan
- first_name: Shian Jang
full_name: Yan, Shian Jang
last_name: Yan
- first_name: Zhen
full_name: Yan, Zhen
last_name: Yan
- first_name: Yasuo
full_name: Yanagi, Yasuo
last_name: Yanagi
- first_name: Chuanbin
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- first_name: Dun Sheng
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last_name: Yang
- first_name: Huan
full_name: Yang, Huan
last_name: Yang
- first_name: Huang Tian
full_name: Yang, Huang Tian
last_name: Yang
- first_name: Hui
full_name: Yang, Hui
last_name: Yang
- first_name: Jin Ming
full_name: Yang, Jin Ming
last_name: Yang
- first_name: Jing
full_name: Yang, Jing
last_name: Yang
- first_name: Jingyu
full_name: Yang, Jingyu
last_name: Yang
- first_name: Ling
full_name: Yang, Ling
last_name: Yang
- first_name: Liu
full_name: Yang, Liu
last_name: Yang
- first_name: Ming
full_name: Yang, Ming
last_name: Yang
- first_name: Pei Ming
full_name: Yang, Pei Ming
last_name: Yang
- first_name: Qian
full_name: Yang, Qian
last_name: Yang
- first_name: Seungwon
full_name: Yang, Seungwon
last_name: Yang
- first_name: Shu
full_name: Yang, Shu
last_name: Yang
- first_name: Shun Fa
full_name: Yang, Shun Fa
last_name: Yang
- first_name: Wannian
full_name: Yang, Wannian
last_name: Yang
- first_name: Wei Yuan
full_name: Yang, Wei Yuan
last_name: Yang
- first_name: Xiaoyong
full_name: Yang, Xiaoyong
last_name: Yang
- first_name: Xuesong
full_name: Yang, Xuesong
last_name: Yang
- first_name: Yi
full_name: Yang, Yi
last_name: Yang
- first_name: Ying
full_name: Yang, Ying
last_name: Yang
- first_name: Honghong
full_name: Yao, Honghong
last_name: Yao
- first_name: Shenggen
full_name: Yao, Shenggen
last_name: Yao
- first_name: Xiaoqiang
full_name: Yao, Xiaoqiang
last_name: Yao
- first_name: Yong Gang
full_name: Yao, Yong Gang
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- first_name: Yong Ming
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last_name: Yao
- first_name: Takahiro
full_name: Yasui, Takahiro
last_name: Yasui
- first_name: Meysam
full_name: Yazdankhah, Meysam
last_name: Yazdankhah
- first_name: Paul M.
full_name: Yen, Paul M.
last_name: Yen
- first_name: Cong
full_name: Yi, Cong
last_name: Yi
- first_name: Xiao Ming
full_name: Yin, Xiao Ming
last_name: Yin
- first_name: Yanhai
full_name: Yin, Yanhai
last_name: Yin
- first_name: Zhangyuan
full_name: Yin, Zhangyuan
last_name: Yin
- first_name: Ziyi
full_name: Yin, Ziyi
last_name: Yin
- first_name: Meidan
full_name: Ying, Meidan
last_name: Ying
- first_name: Zheng
full_name: Ying, Zheng
last_name: Ying
- first_name: Calvin K.
full_name: Yip, Calvin K.
last_name: Yip
- first_name: Stephanie Pei Tung
full_name: Yiu, Stephanie Pei Tung
last_name: Yiu
- first_name: Young H.
full_name: Yoo, Young H.
last_name: Yoo
- first_name: Kiyotsugu
full_name: Yoshida, Kiyotsugu
last_name: Yoshida
- first_name: Saori R.
full_name: Yoshii, Saori R.
last_name: Yoshii
- first_name: Tamotsu
full_name: Yoshimori, Tamotsu
last_name: Yoshimori
- first_name: Bahman
full_name: Yousefi, Bahman
last_name: Yousefi
- first_name: Boxuan
full_name: Yu, Boxuan
last_name: Yu
- first_name: Haiyang
full_name: Yu, Haiyang
last_name: Yu
- first_name: Jun
full_name: Yu, Jun
last_name: Yu
- first_name: Jun
full_name: Yu, Jun
last_name: Yu
- first_name: Li
full_name: Yu, Li
last_name: Yu
- first_name: Ming Lung
full_name: Yu, Ming Lung
last_name: Yu
- first_name: Seong Woon
full_name: Yu, Seong Woon
last_name: Yu
- first_name: Victor C.
full_name: Yu, Victor C.
last_name: Yu
- first_name: W. Haung
full_name: Yu, W. Haung
last_name: Yu
- first_name: Zhengping
full_name: Yu, Zhengping
last_name: Yu
- first_name: Zhou
full_name: Yu, Zhou
last_name: Yu
- first_name: Junying
full_name: Yuan, Junying
last_name: Yuan
- first_name: Ling Qing
full_name: Yuan, Ling Qing
last_name: Yuan
- first_name: Shilin
full_name: Yuan, Shilin
last_name: Yuan
- first_name: Shyng Shiou F.
full_name: Yuan, Shyng Shiou F.
last_name: Yuan
- first_name: Yanggang
full_name: Yuan, Yanggang
last_name: Yuan
- first_name: Zengqiang
full_name: Yuan, Zengqiang
last_name: Yuan
- first_name: Jianbo
full_name: Yue, Jianbo
last_name: Yue
- first_name: Zhenyu
full_name: Yue, Zhenyu
last_name: Yue
- first_name: Jeanho
full_name: Yun, Jeanho
last_name: Yun
- first_name: Raymond L.
full_name: Yung, Raymond L.
last_name: Yung
- first_name: David N.
full_name: Zacks, David N.
last_name: Zacks
- first_name: Gabriele
full_name: Zaffagnini, Gabriele
last_name: Zaffagnini
- first_name: Vanessa O.
full_name: Zambelli, Vanessa O.
last_name: Zambelli
- first_name: Isabella
full_name: Zanella, Isabella
last_name: Zanella
- first_name: Qun S.
full_name: Zang, Qun S.
last_name: Zang
- first_name: Sara
full_name: Zanivan, Sara
last_name: Zanivan
- first_name: Silvia
full_name: Zappavigna, Silvia
last_name: Zappavigna
- first_name: Pilar
full_name: Zaragoza, Pilar
last_name: Zaragoza
- first_name: Konstantinos S.
full_name: Zarbalis, Konstantinos S.
last_name: Zarbalis
- first_name: Amir
full_name: Zarebkohan, Amir
last_name: Zarebkohan
- first_name: Amira
full_name: Zarrouk, Amira
last_name: Zarrouk
- first_name: Scott O.
full_name: Zeitlin, Scott O.
last_name: Zeitlin
- first_name: Jialiu
full_name: Zeng, Jialiu
last_name: Zeng
- first_name: Ju Deng
full_name: Zeng, Ju Deng
last_name: Zeng
- first_name: Eva
full_name: Žerovnik, Eva
last_name: Žerovnik
- first_name: Lixuan
full_name: Zhan, Lixuan
last_name: Zhan
- first_name: Bin
full_name: Zhang, Bin
last_name: Zhang
- first_name: Donna D.
full_name: Zhang, Donna D.
last_name: Zhang
- first_name: Hanlin
full_name: Zhang, Hanlin
last_name: Zhang
- first_name: Hong
full_name: Zhang, Hong
last_name: Zhang
- first_name: Hong
full_name: Zhang, Hong
last_name: Zhang
- first_name: Honghe
full_name: Zhang, Honghe
last_name: Zhang
- first_name: Huafeng
full_name: Zhang, Huafeng
last_name: Zhang
- first_name: Huaye
full_name: Zhang, Huaye
last_name: Zhang
- first_name: Hui
full_name: Zhang, Hui
last_name: Zhang
- first_name: Hui Ling
full_name: Zhang, Hui Ling
last_name: Zhang
- first_name: Jianbin
full_name: Zhang, Jianbin
last_name: Zhang
- first_name: Jianhua
full_name: Zhang, Jianhua
last_name: Zhang
- first_name: Jing Pu
full_name: Zhang, Jing Pu
last_name: Zhang
- first_name: Kalin Y.B.
full_name: Zhang, Kalin Y.B.
last_name: Zhang
- first_name: Leshuai W.
full_name: Zhang, Leshuai W.
last_name: Zhang
- first_name: Lin
full_name: Zhang, Lin
last_name: Zhang
- first_name: Lisheng
full_name: Zhang, Lisheng
last_name: Zhang
- first_name: Lu
full_name: Zhang, Lu
last_name: Zhang
- first_name: Luoying
full_name: Zhang, Luoying
last_name: Zhang
- first_name: Menghuan
full_name: Zhang, Menghuan
last_name: Zhang
- first_name: Peng
full_name: Zhang, Peng
last_name: Zhang
- first_name: Sheng
full_name: Zhang, Sheng
last_name: Zhang
- first_name: Wei
full_name: Zhang, Wei
last_name: Zhang
- first_name: Xiangnan
full_name: Zhang, Xiangnan
last_name: Zhang
- first_name: Xiao Wei
full_name: Zhang, Xiao Wei
last_name: Zhang
- first_name: Xiaolei
full_name: Zhang, Xiaolei
last_name: Zhang
- first_name: Xiaoyan
full_name: Zhang, Xiaoyan
last_name: Zhang
- first_name: Xin
full_name: Zhang, Xin
last_name: Zhang
- first_name: Xinxin
full_name: Zhang, Xinxin
last_name: Zhang
- first_name: Xu Dong
full_name: Zhang, Xu Dong
last_name: Zhang
- first_name: Yang
full_name: Zhang, Yang
last_name: Zhang
- first_name: Yanjin
full_name: Zhang, Yanjin
last_name: Zhang
- first_name: Yi
full_name: Zhang, Yi
last_name: Zhang
- first_name: Ying Dong
full_name: Zhang, Ying Dong
last_name: Zhang
- first_name: Yingmei
full_name: Zhang, Yingmei
last_name: Zhang
- first_name: Yuan Yuan
full_name: Zhang, Yuan Yuan
last_name: Zhang
- first_name: Yuchen
full_name: Zhang, Yuchen
last_name: Zhang
- first_name: Zhe
full_name: Zhang, Zhe
last_name: Zhang
- first_name: Zhengguang
full_name: Zhang, Zhengguang
last_name: Zhang
- first_name: Zhibing
full_name: Zhang, Zhibing
last_name: Zhang
- first_name: Zhihai
full_name: Zhang, Zhihai
last_name: Zhang
- first_name: Zhiyong
full_name: Zhang, Zhiyong
last_name: Zhang
- first_name: Zili
full_name: Zhang, Zili
last_name: Zhang
- first_name: Haobin
full_name: Zhao, Haobin
last_name: Zhao
- first_name: Lei
full_name: Zhao, Lei
last_name: Zhao
- first_name: Shuang
full_name: Zhao, Shuang
last_name: Zhao
- first_name: Tongbiao
full_name: Zhao, Tongbiao
last_name: Zhao
- first_name: Xiao Fan
full_name: Zhao, Xiao Fan
last_name: Zhao
- first_name: Ying
full_name: Zhao, Ying
last_name: Zhao
- first_name: Yongchao
full_name: Zhao, Yongchao
last_name: Zhao
- first_name: Yongliang
full_name: Zhao, Yongliang
last_name: Zhao
- first_name: Yuting
full_name: Zhao, Yuting
last_name: Zhao
- first_name: Guoping
full_name: Zheng, Guoping
last_name: Zheng
- first_name: Kai
full_name: Zheng, Kai
last_name: Zheng
- first_name: Ling
full_name: Zheng, Ling
last_name: Zheng
- first_name: Shizhong
full_name: Zheng, Shizhong
last_name: Zheng
- first_name: Xi Long
full_name: Zheng, Xi Long
last_name: Zheng
- first_name: Yi
full_name: Zheng, Yi
last_name: Zheng
- first_name: Zu Guo
full_name: Zheng, Zu Guo
last_name: Zheng
- first_name: Boris
full_name: Zhivotovsky, Boris
last_name: Zhivotovsky
- first_name: Qing
full_name: Zhong, Qing
last_name: Zhong
- first_name: Ao
full_name: Zhou, Ao
last_name: Zhou
- first_name: Ben
full_name: Zhou, Ben
last_name: Zhou
- first_name: Cefan
full_name: Zhou, Cefan
last_name: Zhou
- first_name: Gang
full_name: Zhou, Gang
last_name: Zhou
- first_name: Hao
full_name: Zhou, Hao
last_name: Zhou
- first_name: Hong
full_name: Zhou, Hong
last_name: Zhou
- first_name: Hongbo
full_name: Zhou, Hongbo
last_name: Zhou
- first_name: Jie
full_name: Zhou, Jie
last_name: Zhou
- first_name: Jing
full_name: Zhou, Jing
last_name: Zhou
- first_name: Jing
full_name: Zhou, Jing
last_name: Zhou
- first_name: Jiyong
full_name: Zhou, Jiyong
last_name: Zhou
- first_name: Kailiang
full_name: Zhou, Kailiang
last_name: Zhou
- first_name: Rongjia
full_name: Zhou, Rongjia
last_name: Zhou
- first_name: Xu Jie
full_name: Zhou, Xu Jie
last_name: Zhou
- first_name: Yanshuang
full_name: Zhou, Yanshuang
last_name: Zhou
- first_name: Yinghong
full_name: Zhou, Yinghong
last_name: Zhou
- first_name: Yubin
full_name: Zhou, Yubin
last_name: Zhou
- first_name: Zheng Yu
full_name: Zhou, Zheng Yu
last_name: Zhou
- first_name: Zhou
full_name: Zhou, Zhou
last_name: Zhou
- first_name: Binglin
full_name: Zhu, Binglin
last_name: Zhu
- first_name: Changlian
full_name: Zhu, Changlian
last_name: Zhu
- first_name: Guo Qing
full_name: Zhu, Guo Qing
last_name: Zhu
- first_name: Haining
full_name: Zhu, Haining
last_name: Zhu
- first_name: Hongxin
full_name: Zhu, Hongxin
last_name: Zhu
- first_name: Hua
full_name: Zhu, Hua
last_name: Zhu
- first_name: Wei Guo
full_name: Zhu, Wei Guo
last_name: Zhu
- first_name: Yanping
full_name: Zhu, Yanping
last_name: Zhu
- first_name: Yushan
full_name: Zhu, Yushan
last_name: Zhu
- first_name: Haixia
full_name: Zhuang, Haixia
last_name: Zhuang
- first_name: Xiaohong
full_name: Zhuang, Xiaohong
last_name: Zhuang
- first_name: Katarzyna
full_name: Zientara-Rytter, Katarzyna
last_name: Zientara-Rytter
- first_name: Christine M.
full_name: Zimmermann, Christine M.
last_name: Zimmermann
- first_name: Elena
full_name: Ziviani, Elena
last_name: Ziviani
- first_name: Teresa
full_name: Zoladek, Teresa
last_name: Zoladek
- first_name: Wei Xing
full_name: Zong, Wei Xing
last_name: Zong
- first_name: Dmitry B.
full_name: Zorov, Dmitry B.
last_name: Zorov
- first_name: Antonio
full_name: Zorzano, Antonio
last_name: Zorzano
- first_name: Weiping
full_name: Zou, Weiping
last_name: Zou
- first_name: Zhen
full_name: Zou, Zhen
last_name: Zou
- first_name: Zhengzhi
full_name: Zou, Zhengzhi
last_name: Zou
- first_name: Steven
full_name: Zuryn, Steven
last_name: Zuryn
- first_name: Werner
full_name: Zwerschke, Werner
last_name: Zwerschke
- first_name: Beate
full_name: Brand-Saberi, Beate
last_name: Brand-Saberi
- first_name: X. Charlie
full_name: Dong, X. Charlie
last_name: Dong
- first_name: Chandra Shekar
full_name: Kenchappa, Chandra Shekar
last_name: Kenchappa
- first_name: Zuguo
full_name: Li, Zuguo
last_name: Li
- first_name: Yong
full_name: Lin, Yong
last_name: Lin
- first_name: Shigeru
full_name: Oshima, Shigeru
last_name: Oshima
- first_name: Yueguang
full_name: Rong, Yueguang
last_name: Rong
- first_name: Judith C.
full_name: Sluimer, Judith C.
last_name: Sluimer
- first_name: Christina L.
full_name: Stallings, Christina L.
last_name: Stallings
- first_name: Chun Kit
full_name: Tong, Chun Kit
last_name: Tong
citation:
ama: Klionsky DJ, Abdel-Aziz AK, Abdelfatah S, et al. Guidelines for the use and
interpretation of assays for monitoring autophagy (4th edition). Autophagy.
2021;17(1):1-382. doi:10.1080/15548627.2020.1797280
apa: Klionsky, D. J., Abdel-Aziz, A. K., Abdelfatah, S., Abdellatif, M., Abdoli,
A., Abel, S., … Tong, C. K. (2021). Guidelines for the use and interpretation
of assays for monitoring autophagy (4th edition). Autophagy. Taylor &
Francis. https://doi.org/10.1080/15548627.2020.1797280
chicago: Klionsky, Daniel J., Amal Kamal Abdel-Aziz, Sara Abdelfatah, Mahmoud Abdellatif,
Asghar Abdoli, Steffen Abel, Hagai Abeliovich, et al. “Guidelines for the Use
and Interpretation of Assays for Monitoring Autophagy (4th Edition).” Autophagy.
Taylor & Francis, 2021. https://doi.org/10.1080/15548627.2020.1797280.
ieee: D. J. Klionsky et al., “Guidelines for the use and interpretation of
assays for monitoring autophagy (4th edition),” Autophagy, vol. 17, no.
1. Taylor & Francis, pp. 1–382, 2021.
ista: Klionsky DJ et al. 2021. Guidelines for the use and interpretation of assays
for monitoring autophagy (4th edition). Autophagy. 17(1), 1–382.
mla: Klionsky, Daniel J., et al. “Guidelines for the Use and Interpretation of Assays
for Monitoring Autophagy (4th Edition).” Autophagy, vol. 17, no. 1, Taylor
& Francis, 2021, pp. 1–382, doi:10.1080/15548627.2020.1797280.
short: D.J. Klionsky, A.K. Abdel-Aziz, S. Abdelfatah, M. Abdellatif, A. Abdoli,
S. Abel, H. Abeliovich, M.H. Abildgaard, Y.P. Abudu, A. Acevedo-Arozena, I.E.
Adamopoulos, K. Adeli, T.E. Adolph, A. Adornetto, E. Aflaki, G. Agam, A. Agarwal,
B.B. Aggarwal, M. Agnello, P. Agostinis, J.N. Agrewala, A. Agrotis, P.V. Aguilar,
S.T. Ahmad, Z.M. Ahmed, U. Ahumada-Castro, S. Aits, S. Aizawa, Y. Akkoc, T. Akoumianaki,
H.A. Akpinar, A.M. Al-Abd, L. Al-Akra, A. Al-Gharaibeh, M.A. Alaoui-Jamali, S.
Alberti, E. Alcocer-Gómez, C. Alessandri, M. Ali, M.A. Alim Al-Bari, S. Aliwaini,
J. Alizadeh, E. Almacellas, A. Almasan, A. Alonso, G.D. Alonso, N. Altan-Bonnet,
D.C. Altieri, É.M.C. Álvarez, S. Alves, C. Alves Da Costa, M.M. Alzaharna, M.
Amadio, C. Amantini, C. Amaral, S. Ambrosio, A.O. Amer, V. Ammanathan, Z. An,
S.U. Andersen, S.A. Andrabi, M. Andrade-Silva, A.M. Andres, S. Angelini, D. Ann,
U.C. Anozie, M.Y. Ansari, P. Antas, A. Antebi, Z. Antón, T. Anwar, L. Apetoh,
N. Apostolova, T. Araki, Y. Araki, K. Arasaki, W.L. Araújo, J. Araya, C. Arden,
M.A. Arévalo, S. Arguelles, E. Arias, J. Arikkath, H. Arimoto, A.R. Ariosa, D.
Armstrong-James, L. Arnauné-Pelloquin, A. Aroca, D.S. Arroyo, I. Arsov, R. Artero,
D.M.L. Asaro, M. Aschner, M. Ashrafizadeh, O. Ashur-Fabian, A.G. Atanasov, A.K.
Au, P. Auberger, H.W. Auner, L. Aurelian, R. Autelli, L. Avagliano, Y. Ávalos,
S. Aveic, C.A. Aveleira, T. Avin-Wittenberg, Y. Aydin, S. Ayton, S. Ayyadevara,
M. Azzopardi, M. Baba, J.M. Backer, S.K. Backues, D.H. Bae, O.N. Bae, S.H. Bae,
E.H. Baehrecke, A. Baek, S.H. Baek, S.H. Baek, G. Bagetta, A. Bagniewska-Zadworna,
H. Bai, J. Bai, X. Bai, Y. Bai, N. Bairagi, S. Baksi, T. Balbi, C.T. Baldari,
W. Balduini, A. Ballabio, M. Ballester, S. Balazadeh, R. Balzan, R. Bandopadhyay,
S. Banerjee, S. Banerjee, Á. Bánréti, Y. Bao, M.S. Baptista, A. Baracca, C. Barbati,
A. Bargiela, D. Barilà, P.G. Barlow, S.J. Barmada, E. Barreiro, G.E. Barreto,
J. Bartek, B. Bartel, A. Bartolome, G.R. Barve, S.H. Basagoudanavar, D.C. Bassham,
R.C. Bast, A. Basu, H. Batoko, I. Batten, E.E. Baulieu, B.L. Baumgarner, J. Bayry,
R. Beale, I. Beau, F. Beaumatin, L.R.G. Bechara, G.R. Beck, M.F. Beers, J. Begun,
C. Behrends, G.M.N. Behrens, R. Bei, E. Bejarano, S. Bel, C. Behl, A. Belaid,
N. Belgareh-Touzé, C. Bellarosa, F. Belleudi, M. Belló Pérez, R. Bello-Morales,
J.S.D.O. Beltran, S. Beltran, D.M. Benbrook, M. Bendorius, B.A. Benitez, I. Benito-Cuesta,
J. Bensalem, M.W. Berchtold, S. Berezowska, D. Bergamaschi, M. Bergami, A. Bergmann,
L. Berliocchi, C. Berlioz-Torrent, A. Bernard, L. Berthoux, C.G. Besirli, S. Besteiro,
V.M. Betin, R. Beyaert, J.S. Bezbradica, K. Bhaskar, I. Bhatia-Kissova, R. Bhattacharya,
S. Bhattacharya, S. Bhattacharyya, M.S. Bhuiyan, S.K. Bhutia, L. Bi, X. Bi, T.J.
Biden, K. Bijian, V.A. Billes, N. Binart, C. Bincoletto, A.B. Birgisdottir, G.
Bjorkoy, G. Blanco, A. Blas-Garcia, J. Blasiak, R. Blomgran, K. Blomgren, J.S.
Blum, E. Boada-Romero, M. Boban, K. Boesze-Battaglia, P. Boeuf, B. Boland, P.
Bomont, P. Bonaldo, S.R. Bonam, L. Bonfili, J.S. Bonifacino, B.A. Boone, M.D.
Bootman, M. Bordi, C. Borner, B.C. Bornhauser, G. Borthakur, J. Bosch, S. Bose,
L.M. Botana, J. Botas, C.M. Boulanger, M.E. Boulton, M. Bourdenx, B. Bourgeois,
N.M. Bourke, G. Bousquet, P. Boya, P.V. Bozhkov, L.H.M. Bozi, T.O. Bozkurt, D.E.
Brackney, C.H. Brandts, R.J. Braun, G.H. Braus, R. Bravo-Sagua, J.M. Bravo-San
Pedro, P. Brest, M.A. Bringer, A. Briones-Herrera, V.C. Broaddus, P. Brodersen,
J.L. Brodsky, S.L. Brody, P.G. Bronson, J.M. Bronstein, C.N. Brown, R.E. Brown,
P.C. Brum, J.H. Brumell, N. Brunetti-Pierri, D. Bruno, R.J. Bryson-Richardson,
C. Bucci, C. Buchrieser, M. Bueno, L.E. Buitrago-Molina, S. Buraschi, S. Buch,
J.R. Buchan, E.M. Buckingham, H. Budak, M. Budini, G. Bultynck, F. Burada, J.R.
Burgoyne, M.I. Burón, V. Bustos, S. Büttner, E. Butturini, A. Byrd, I. Cabas,
S. Cabrera-Benitez, K. Cadwell, J. Cai, L. Cai, Q. Cai, M. Cairó, J.A. Calbet,
G.A. Caldwell, K.A. Caldwell, J.A. Call, R. Calvani, A.C. Calvo, M. Calvo-Rubio
Barrera, N.O.S. Camara, J.H. Camonis, N. Camougrand, M. Campanella, E.M. Campbell,
F.X. Campbell-Valois, S. Campello, I. Campesi, J.C. Campos, O. Camuzard, J. Cancino,
D. Candido De Almeida, L. Canesi, I. Caniggia, B. Canonico, C. Cantí, B. Cao,
M. Caraglia, B. Caramés, E.H. Carchman, E. Cardenal-Muñoz, C. Cardenas, L. Cardenas,
S.M. Cardoso, J.S. Carew, G.F. Carle, G. Carleton, S. Carloni, D. Carmona-Gutierrez,
L.A. Carneiro, O. Carnevali, J.M. Carosi, S. Carra, A. Carrier, L. Carrier, B.
Carroll, A.B. Carter, A.N. Carvalho, M. Casanova, C. Casas, J. Casas, C. Cassioli,
E.F. Castillo, K. Castillo, S. Castillo-Lluva, F. Castoldi, M. Castori, A.F. Castro,
M. Castro-Caldas, J. Castro-Hernandez, S. Castro-Obregon, S.D. Catz, C. Cavadas,
F. Cavaliere, G. Cavallini, M. Cavinato, M.L. Cayuela, P. Cebollada Rica, V. Cecarini,
F. Cecconi, M. Cechowska-Pasko, S. Cenci, V. Ceperuelo-Mallafré, J.J. Cerqueira,
J.M. Cerutti, D. Cervia, V.B. Cetintas, S. Cetrullo, H.J. Chae, A.S. Chagin, C.Y.
Chai, G. Chakrabarti, O. Chakrabarti, T. Chakraborty, T. Chakraborty, M. Chami,
G. Chamilos, D.W. Chan, E.Y.W. Chan, E.D. Chan, H.Y.E. Chan, H.H. Chan, H. Chan,
M.T.V. Chan, Y.S. Chan, P.K. Chandra, C.P. Chang, C. Chang, H.C. Chang, K. Chang,
J. Chao, T. Chapman, N. Charlet-Berguerand, S. Chatterjee, S.K. Chaube, A. Chaudhary,
S. Chauhan, E. Chaum, F. Checler, M.E. Cheetham, C.S. Chen, G.C. Chen, J.F. Chen,
L.L. Chen, L. Chen, L. Chen, M. Chen, M.K. Chen, N. Chen, Q. Chen, R.H. Chen,
S. Chen, W. Chen, W. Chen, X.M. Chen, X.W. Chen, X. Chen, Y. Chen, Y.G. Chen,
Y. Chen, Y. Chen, Y.J. Chen, Y.Q. Chen, Z.S. Chen, Z. Chen, Z.H. Chen, Z.J. Chen,
Z. Chen, H. Cheng, J. Cheng, S.Y. Cheng, W. Cheng, X. Cheng, X.T. Cheng, Y. Cheng,
Z. Cheng, Z. Chen, H. Cheong, J.K. Cheong, B.V. Chernyak, S. Cherry, C.F.R. Cheung,
C.H.A. Cheung, K.H. Cheung, E. Chevet, R.J. Chi, A.K.S. Chiang, F. Chiaradonna,
R. Chiarelli, M. Chiariello, N. Chica, S. Chiocca, M. Chiong, S.H. Chiou, A.I.
Chiramel, V. Chiurchiù, D.H. Cho, S.K. Choe, A.M.K. Choi, M.E. Choi, K.R. Choudhury,
N.S. Chow, C.T. Chu, J.P. Chua, J.J.E. Chua, H. Chung, K.P. Chung, S. Chung, S.H.
Chung, Y.L. Chung, V. Cianfanelli, I.A. Ciechomska, M. Cifuentes, L. Cinque, S.
Cirak, M. Cirone, M.J. Clague, R. Clarke, E. Clementi, E.M. Coccia, P. Codogno,
E. Cohen, M.M. Cohen, T. Colasanti, F. Colasuonno, R.A. Colbert, A. Colell, M.
Čolić, N.S. Coll, M.O. Collins, M.I. Colombo, D.A. Colón-Ramos, L. Combaret, S.
Comincini, M.R. Cominetti, A. Consiglio, A. Conte, F. Conti, V.R. Contu, M.R.
Cookson, K.M. Coombs, I. Coppens, M.T. Corasaniti, D.P. Corkery, N. Cordes, K.
Cortese, M.D.C. Costa, S. Costantino, P. Costelli, A. Coto-Montes, P.J. Crack,
J.L. Crespo, A. Criollo, V. Crippa, R. Cristofani, T. Csizmadia, A. Cuadrado,
B. Cui, J. Cui, Y. Cui, Y. Cui, E. Culetto, A.C. Cumino, A.V. Cybulsky, M.J. Czaja,
S.J. Czuczwar, S. D’Adamo, M. D’Amelio, D. D’Arcangelo, A.C. D’Lugos, G. D’Orazi,
J.A. Da Silva, H.S. Dafsari, R.K. Dagda, Y. Dagdas, M. Daglia, X. Dai, Y. Dai,
Y. Dai, J. Dal Col, P. Dalhaimer, L. Dalla Valle, T. Dallenga, G. Dalmasso, M.
Damme, I. Dando, N.P. Dantuma, A.L. Darling, H. Das, S. Dasarathy, S.K. Dasari,
S. Dash, O. Daumke, A.N. Dauphinee, J.S. Davies, V.A. Dávila, R.J. Davis, T. Davis,
S. Dayalan Naidu, F. De Amicis, K. De Bosscher, F. De Felice, L. De Franceschi,
C. De Leonibus, M.G. De Mattos Barbosa, G.R.Y. De Meyer, A. De Milito, C. De Nunzio,
C. De Palma, M. De Santi, C. De Virgilio, D. De Zio, J. Debnath, B.J. Debosch,
J.P. Decuypere, M.A. Deehan, G. Deflorian, J. Degregori, B. Dehay, G. Del Rio,
J.R. Delaney, L.M.D. Delbridge, E. Delorme-Axford, M.V. Delpino, F. Demarchi,
V. Dembitz, N.D. Demers, H. Deng, Z. Deng, J. Dengjel, P. Dent, D. Denton, M.L.
Depamphilis, C.J. Der, V. Deretic, A. Descoteaux, L. Devis, S. Devkota, O. Devuyst,
G. Dewson, M. Dharmasivam, R. Dhiman, D. Di Bernardo, M. Di Cristina, F. Di Domenico,
P. Di Fazio, A. Di Fonzo, G. Di Guardo, G.M. Di Guglielmo, L. Di Leo, C. Di Malta,
A. Di Nardo, M. Di Rienzo, F. Di Sano, G. Diallinas, J. Diao, G. Diaz-Araya, I.
Díaz-Laviada, J.M. Dickinson, M. Diederich, M. Dieudé, I. Dikic, S. Ding, W.X.
Ding, L. Dini, J. Dinić, M. Dinic, A.T. Dinkova-Kostova, M.S. Dionne, J.H.W. Distler,
A. Diwan, I.M.C. Dixon, M. Djavaheri-Mergny, I. Dobrinski, O. Dobrovinskaya, R.
Dobrowolski, R.C.J. Dobson, J. Đokić, S. Dokmeci Emre, M. Donadelli, B. Dong,
X. Dong, Z. Dong, G.W. Dorn, V. Dotsch, H. Dou, J. Dou, M. Dowaidar, S. Dridi,
L. Drucker, A. Du, C. Du, G. Du, H.N. Du, L.L. Du, A. Du Toit, S.B. Duan, X. Duan,
S.P. Duarte, A. Dubrovska, E.A. Dunlop, N. Dupont, R.V. Durán, B.S. Dwarakanath,
S.A. Dyshlovoy, D. Ebrahimi-Fakhari, L. Eckhart, C.L. Edelstein, T. Efferth, E.
Eftekharpour, L. Eichinger, N. Eid, T. Eisenberg, N.T. Eissa, S. Eissa, M. Ejarque,
A. El Andaloussi, N. El-Hage, S. El-Naggar, A.M. Eleuteri, E.S. El-Shafey, M.
Elgendy, A.G. Eliopoulos, M.M. Elizalde, P.M. Elks, H.P. Elsasser, E.S. Elsherbiny,
B.M. Emerling, N.C.T. Emre, C.H. Eng, N. Engedal, A.M. Engelbrecht, A.S.T. Engelsen,
J.M. Enserink, R. Escalante, A. Esclatine, M. Escobar-Henriques, E.L. Eskelinen,
L. Espert, M.O. Eusebio, G. Fabrias, C. Fabrizi, A. Facchiano, F. Facchiano, B.
Fadeel, C. Fader, A.C. Faesen, W.D. Fairlie, A. Falcó, B.H. Falkenburger, D. Fan,
J. Fan, Y. Fan, E.F. Fang, Y. Fang, Y. Fang, M. Fanto, T. Farfel-Becker, M. Faure,
G. Fazeli, A.O. Fedele, A.M. Feldman, D. Feng, J. Feng, L. Feng, Y. Feng, Y. Feng,
W. Feng, T. Fenz Araujo, T.A. Ferguson, Á.F. Fernández, J.C. Fernandez-Checa,
S. Fernández-Veledo, A.R. Fernie, A.W. Ferrante, A. Ferraresi, M.F. Ferrari, J.C.B.
Ferreira, S. Ferro-Novick, A. Figueras, R. Filadi, N. Filigheddu, E. Filippi-Chiela,
G. Filomeni, G.M. Fimia, V. Fineschi, F. Finetti, S. Finkbeiner, E.A. Fisher,
P.B. Fisher, F. Flamigni, S.J. Fliesler, T.H. Flo, I. Florance, O. Florey, T.
Florio, E. Fodor, C. Follo, E.A. Fon, A. Forlino, F. Fornai, P. Fortini, A. Fracassi,
A. Fraldi, B. Franco, R. Franco, F. Franconi, L.B. Frankel, S.L. Friedman, L.F.
Fröhlich, G. Frühbeck, J.M. Fuentes, Y. Fujiki, N. Fujita, Y. Fujiwara, M. Fukuda,
S. Fulda, L. Furic, N. Furuya, C. Fusco, M.U. Gack, L. Gaffke, S. Galadari, A.
Galasso, M.F. Galindo, S. Gallolu Kankanamalage, L. Galluzzi, V. Galy, N. Gammoh,
B. Gan, I.G. Ganley, F. Gao, H. Gao, M. Gao, P. Gao, S.J. Gao, W. Gao, X. Gao,
A. Garcera, M.N. Garcia, V.E. Garcia, F. García-Del Portillo, V. Garcia-Escudero,
A. Garcia-Garcia, M. Garcia-Macia, D. García-Moreno, C. Garcia-Ruiz, P. García-Sanz,
A.D. Garg, R. Gargini, T. Garofalo, R.F. Garry, N.C. Gassen, D. Gatica, L. Ge,
W. Ge, R. Geiss-Friedlander, C. Gelfi, P. Genschik, I.E. Gentle, V. Gerbino, C.
Gerhardt, K. Germain, M. Germain, D.A. Gewirtz, E. Ghasemipour Afshar, S. Ghavami,
A. Ghigo, M. Ghosh, G. Giamas, C. Giampietri, A. Giatromanolaki, G.E. Gibson,
S.B. Gibson, V. Ginet, E. Giniger, C. Giorgi, H. Girao, S.E. Girardin, M. Giridharan,
S. Giuliano, C. Giulivi, S. Giuriato, J. Giustiniani, A. Gluschko, V. Goder, A.
Goginashvili, J. Golab, D.C. Goldstone, A. Golebiewska, L.R. Gomes, R. Gomez,
R. Gómez-Sánchez, M.C. Gomez-Puerto, R. Gomez-Sintes, Q. Gong, F.M. Goni, J. González-Gallego,
T. Gonzalez-Hernandez, R.A. Gonzalez-Polo, J.A. Gonzalez-Reyes, P. González-Rodríguez,
I.S. Goping, M.S. Gorbatyuk, N.V. Gorbunov, K. Görgülü, R.M. Gorojod, S.M. Gorski,
S. Goruppi, C. Gotor, R.A. Gottlieb, I. Gozes, D. Gozuacik, M. Graef, M.H. Gräler,
V. Granatiero, D. Grasso, J.P. Gray, D.R. Green, A. Greenhough, S.L. Gregory,
E.F. Griffin, M.W. Grinstaff, F. Gros, C. Grose, A.S. Gross, F. Gruber, P. Grumati,
T. Grune, X. Gu, J.L. Guan, C.M. Guardia, K. Guda, F. Guerra, C. Guerri, P. Guha,
C. Guillén, S. Gujar, A. Gukovskaya, I. Gukovsky, J. Gunst, A. Günther, A.R. Guntur,
C. Guo, C. Guo, H. Guo, L.W. Guo, M. Guo, P. Gupta, S.K. Gupta, S. Gupta, V.B.
Gupta, V. Gupta, A.B. Gustafsson, D.D. Gutterman, R. H.B, A. Haapasalo, J.E. Haber,
A. Hać, S. Hadano, A.J. Hafrén, M. Haidar, B.S. Hall, G. Halldén, A. Hamacher-Brady,
A. Hamann, M. Hamasaki, W. Han, M. Hansen, P.I.. Hanson, Z. Hao, M. Harada, L.
Harhaji-Trajkovic, N. Hariharan, N. Haroon, J. Harris, T. Hasegawa, N. Hasima
Nagoor, J.A. Haspel, V. Haucke, W.D. Hawkins, B.A. Hay, C.M. Haynes, S.B. Hayrabedyan,
T.S. Hays, C. He, Q. He, R.R. He, Y.W. He, Y.Y. He, Y. Heakal, A.M. Heberle, J.F.
Hejtmancik, G.V. Helgason, V. Henkel, M. Herb, A. Hergovich, A. Herman-Antosiewicz,
A. Hernández, C. Hernandez, S. Hernandez-Diaz, V. Hernandez-Gea, A. Herpin, J.
Herreros, J.H. Hervás, D. Hesselson, C. Hetz, V.T. Heussler, Y. Higuchi, S. Hilfiker,
J.A. Hill, W.S. Hlavacek, E.A. Ho, I.H.T. Ho, P.W.L. Ho, S.L. Ho, W.Y. Ho, G.A.
Hobbs, M. Hochstrasser, P.H.M. Hoet, D. Hofius, P. Hofman, A. Höhn, C.I. Holmberg,
J.R. Hombrebueno, C.W.H. Yi-Ren Hong, L.V. Hooper, T. Hoppe, R. Horos, Y. Hoshida,
I.L. Hsin, H.Y. Hsu, B. Hu, D. Hu, L.F. Hu, M.C. Hu, R. Hu, W. Hu, Y.C. Hu, Z.W.
Hu, F. Hua, J. Hua, Y. Hua, C. Huan, C. Huang, C. Huang, C. Huang, C. Huang, H.
Huang, K. Huang, M.L.H. Huang, R. Huang, S. Huang, T. Huang, X. Huang, Y.J. Huang,
T.B. Huber, V. Hubert, C.A. Hubner, S.M. Hughes, W.E. Hughes, M. Humbert, G. Hummer,
J.H. Hurley, S. Hussain, S. Hussain, P.J. Hussey, M. Hutabarat, H.Y. Hwang, S.
Hwang, A. Ieni, F. Ikeda, Y. Imagawa, Y. Imai, C. Imbriano, M. Imoto, D.M. Inman,
K. Inoki, J. Iovanna, R.V. Iozzo, G. Ippolito, J.E. Irazoqui, P. Iribarren, M.
Ishaq, M. Ishikawa, N. Ishimwe, C. Isidoro, N. Ismail, S. Issazadeh-Navikas, E.
Itakura, D. Ito, D. Ivankovic, S. Ivanova, A.K.V. Iyer, J.M. Izquierdo, M. Izumi,
M. Jäättelä, M.S. Jabir, W.T. Jackson, N. Jacobo-Herrera, A.C. Jacomin, E. Jacquin,
P. Jadiya, H. Jaeschke, C. Jagannath, A.J. Jakobi, J. Jakobsson, B. Janji, P.
Jansen-Dürr, P.J. Jansson, J. Jantsch, S. Januszewski, A. Jassey, S. Jean, H.
Jeltsch-David, P. Jendelova, A. Jenny, T.E. Jensen, N. Jessen, J.L. Jewell, J.
Ji, L. Jia, R. Jia, L. Jiang, Q. Jiang, R. Jiang, T. Jiang, X. Jiang, Y. Jiang,
M. Jimenez-Sanchez, E.J. Jin, F. Jin, H. Jin, L. Jin, L. Jin, M. Jin, S. Jin,
E.K. Jo, C. Joffre, T. Johansen, G.V.W. Johnson, S.A. Johnston, E. Jokitalo, M.K.
Jolly, L.A.B. Joosten, J. Jordan, B. Joseph, D. Ju, J.S. Ju, J. Ju, E. Juárez,
D. Judith, G. Juhász, Y. Jun, C.H. Jung, S.C. Jung, Y.K. Jung, H. Jungbluth, J.
Jungverdorben, S. Just, K. Kaarniranta, A. Kaasik, T. Kabuta, D. Kaganovich, A.
Kahana, R. Kain, S. Kajimura, M. Kalamvoki, M. Kalia, D.S. Kalinowski, N. Kaludercic,
I. Kalvari, J. Kaminska, V.O. Kaminskyy, H. Kanamori, K. Kanasaki, C. Kang, R.
Kang, S.S. Kang, S. Kaniyappan, T. Kanki, T.D. Kanneganti, A.G. Kanthasamy, A.
Kanthasamy, M. Kantorow, O. Kapuy, M.V. Karamouzis, M.R. Karim, P. Karmakar, R.G.
Katare, M. Kato, S.H.E. Kaufmann, A. Kauppinen, G.P. Kaushal, S. Kaushik, K. Kawasaki,
K. Kazan, P.Y. Ke, D.J. Keating, U. Keber, J.H. Kehrl, K.E. Keller, C.W. Keller,
J.K. Kemper, C.M. Kenific, O. Kepp, S. Kermorgant, A. Kern, R. Ketteler, T.G.
Keulers, B. Khalfin, H. Khalil, B. Khambu, S.Y. Khan, V.K.M. Khandelwal, R. Khandia,
W. Kho, N.V. Khobrekar, S. Khuansuwan, M. Khundadze, S.A. Killackey, D. Kim, D.R.
Kim, D.H. Kim, D.E. Kim, E.Y. Kim, E.K. Kim, H.R. Kim, H.S. Kim, U. Hyung-Ryong
Kim, J.H. Kim, J.K. Kim, J.H. Kim, J. Kim, J.H. Kim, K.I. Kim, P.K. Kim, S.J.
Kim, S.R. Kimball, A. Kimchi, A.C. Kimmelman, T. Kimura, M.A. King, K.J. Kinghorn,
C.G. Kinsey, V. Kirkin, L.A. Kirshenbaum, S.L. Kiselev, S. Kishi, K. Kitamoto,
Y. Kitaoka, K. Kitazato, R.N. Kitsis, J.T. Kittler, O. Kjaerulff, P.S. Klein,
T. Klopstock, J. Klucken, H. Knævelsrud, R.L. Knorr, B.C.B. Ko, F. Ko, J.L. Ko,
H. Kobayashi, S. Kobayashi, I. Koch, J.C. Koch, U. Koenig, D. Kögel, Y.H. Koh,
M. Koike, S.D. Kohlwein, N.M. Kocaturk, M. Komatsu, J. König, T. Kono, B.T. Kopp,
T. Korcsmaros, G. Korkmaz, V.I. Korolchuk, M.S. Korsnes, A. Koskela, J. Kota,
Y. Kotake, M.L. Kotler, Y. Kou, M.I. Koukourakis, E. Koustas, A.L. Kovacs, T.
Kovács, D. Koya, T. Kozako, C. Kraft, D. Krainc, H. Krämer, A.D. Krasnodembskaya,
C. Kretz-Remy, G. Kroemer, N.T. Ktistakis, K. Kuchitsu, S. Kuenen, L. Kuerschner,
T. Kukar, A. Kumar, A. Kumar, D. Kumar, D. Kumar, S. Kumar, S. Kume, C. Kumsta,
C.N. Kundu, M. Kundu, A.B. Kunnumakkara, L. Kurgan, T.G. Kutateladze, O. Kutlu,
S.A. Kwak, H.J. Kwon, T.K. Kwon, Y.T. Kwon, I. Kyrmizi, A. La Spada, P. Labonté,
S. Ladoire, I. Laface, F. Lafont, D.C. Lagace, V. Lahiri, Z. Lai, A.S. Laird,
A. Lakkaraju, T. Lamark, S.H. Lan, A. Landajuela, D.J.R. Lane, J.D. Lane, C.H.
Lang, C. Lange, Ü. Langel, R. Langer, P. Lapaquette, J. Laporte, N.F. Larusso,
I. Lastres-Becker, W.C.Y. Lau, G.W. Laurie, S. Lavandero, B.Y.K. Law, H.K.W. Law,
R. Layfield, W. Le, H. Le Stunff, A.Y. Leary, J.J. Lebrun, L.Y.W. Leck, J.P. Leduc-Gaudet,
C. Lee, C.P. Lee, D.H. Lee, E.B. Lee, E.F. Lee, G.M. Lee, H.J. Lee, H.K. Lee,
J.M. Lee, J.S. Lee, J.A. Lee, J.Y. Lee, J.H. Lee, M. Lee, M.G. Lee, M.J. Lee,
M.S. Lee, S.Y. Lee, S.J. Lee, S.Y. Lee, S.B. Lee, W.H. Lee, Y.R. Lee, Y.H. Lee,
Y. Lee, C. Lefebvre, R. Legouis, Y.L. Lei, Y. Lei, S. Leikin, G. Leitinger, L.
Lemus, S. Leng, O. Lenoir, G. Lenz, H.J. Lenz, P. Lenzi, Y. León, A.M. Leopoldino,
C. Leschczyk, S. Leskelä, E. Letellier, C.T. Leung, P.S. Leung, J.S. Leventhal,
B. Levine, P.A. Lewis, K. Ley, B. Li, D.Q. Li, J. Li, J. Li, J. Li, K. Li, L.
Li, M. Li, M. Li, M. Li, M. Li, M. Li, P.L. Li, M.Q. Li, Q. Li, S. Li, T. Li,
W. Li, W. Li, X. Li, Y.P. Li, Y. Li, Z. Li, Z. Li, Z. Li, J. Lian, C. Liang, Q.
Liang, W. Liang, Y. Liang, Y.T. Liang, G. Liao, L. Liao, M. Liao, Y.F. Liao, M.
Librizzi, P.P.Y. Lie, M.A. Lilly, H.J. Lim, T.R.R. Lima, F. Limana, C. Lin, C.W.
Lin, D.S. Lin, F.C. Lin, J.D. Lin, K.M. Lin, K.H. Lin, L.T. Lin, P.H. Lin, Q.
Lin, S. Lin, S.J. Lin, W. Lin, X. Lin, Y.X. Lin, Y.S. Lin, R. Linden, P. Lindner,
S.C. Ling, P. Lingor, A.K. Linnemann, Y.C. Liou, M.M. Lipinski, S. Lipovšek, V.A.
Lira, N. Lisiak, P.B. Liton, C. Liu, C.H. Liu, C.F. Liu, C.H. Liu, F. Liu, H.
Liu, H.S. Liu, H.F. Liu, H. Liu, J. Liu, J. Liu, J. Liu, L. Liu, L. Liu, M. Liu,
Q. Liu, W. Liu, W. Liu, X.H. Liu, X. Liu, X. Liu, X. Liu, X. Liu, Y. Liu, Y. Liu,
Y. Liu, Y. Liu, Y. Liu, J.A. Livingston, G. Lizard, J.M. Lizcano, S. Ljubojevic-Holzer,
M.E. Lleonart, D. Llobet-Navàs, A. Llorente, C.H. Lo, D. Lobato-Márquez, Q. Long,
Y.C. Long, B. Loos, J.A. Loos, M.G. López, G. López-Doménech, J.A. López-Guerrero,
A.T. López-Jiménez, Ó. López-Pérez, I. López-Valero, M.J. Lorenowicz, M. Lorente,
P. Lorincz, L. Lossi, S. Lotersztajn, P.E. Lovat, J.F. Lovell, A. Lovy, P. Lőw,
G. Lu, H. Lu, J.H. Lu, J.J. Lu, M. Lu, S. Lu, A. Luciani, J.M. Lucocq, P. Ludovico,
M.A. Luftig, M. Luhr, D. Luis-Ravelo, J.J. Lum, L. Luna-Dulcey, A.H. Lund, V.K.
Lund, J.D. Lünemann, P. Lüningschrör, H. Luo, R. Luo, S. Luo, Z. Luo, C. Luparello,
B. Lüscher, L. Luu, A. Lyakhovich, K.G. Lyamzaev, A.H. Lystad, L. Lytvynchuk,
A.C. Ma, C. Ma, M. Ma, N.F. Ma, Q.H. Ma, X. Ma, Y. Ma, Z. Ma, O.A. Macdougald,
F. Macian, G.C. Macintosh, J.P. Mackeigan, K.F. Macleod, S. Maday, F. Madeo, M.
Madesh, T. Madl, J. Madrigal-Matute, A. Maeda, Y. Maejima, M. Magarinos, P. Mahavadi,
E. Maiani, K. Maiese, P. Maiti, M.C. Maiuri, B. Majello, M.B. Major, E. Makareeva,
F. Malik, K. Mallilankaraman, W. Malorni, A. Maloyan, N. Mammadova, G.C.W. Man,
F. Manai, J.D. Mancias, E.M. Mandelkow, M.A. Mandell, A.A. Manfredi, M.H. Manjili,
R. Manjithaya, P. Manque, B.B. Manshian, R. Manzano, C. Manzoni, K. Mao, C. Marchese,
S. Marchetti, A.M. Marconi, F. Marcucci, S. Mardente, O.A. Mareninova, M. Margeta,
M. Mari, S. Marinelli, O. Marinelli, G. Mariño, S. Mariotto, R.S. Marshall, M.R.
Marten, S. Martens, A.P.J. Martin, K.R. Martin, S. Martin, S. Martin, A. Martín-Segura,
M.A. Martín-Acebes, I. Martin-Burriel, M. Martin-Rincon, P. Martin-Sanz, J.A.
Martina, W. Martinet, A. Martinez, A. Martinez, J. Martinez, M. Martinez Velazquez,
N. Martinez-Lopez, M. Martinez-Vicente, D.O. Martins, J.O. Martins, W.K. Martins,
T. Martins-Marques, E. Marzetti, S. Masaldan, C. Masclaux-Daubresse, D.G. Mashek,
V. Massa, L. Massieu, G.R. Masson, L. Masuelli, A.I. Masyuk, T.V. Masyuk, P. Matarrese,
A. Matheu, S. Matoba, S. Matsuzaki, P. Mattar, A. Matte, D. Mattoscio, J.L. Mauriz,
M. Mauthe, C. Mauvezin, E. Maverakis, P. Maycotte, J. Mayer, G. Mazzoccoli, C.
Mazzoni, J.R. Mazzulli, N. Mccarty, C. Mcdonald, M.R. Mcgill, S.L. Mckenna, B.A.
Mclaughlin, F. Mcloughlin, M.A. Mcniven, T.G. Mcwilliams, F. Mechta-Grigoriou,
T.C. Medeiros, D.L. Medina, L.A. Megeney, K. Megyeri, M. Mehrpour, J.L. Mehta,
A.J. Meijer, A.H. Meijer, J. Mejlvang, A. Meléndez, A. Melk, G. Memisoglu, A.F.
Mendes, D. Meng, F. Meng, T. Meng, R. Menna-Barreto, M.B. Menon, C. Mercer, A.E.
Mercier, J.L. Mergny, A. Merighi, S.D. Merkley, G. Merla, V. Meske, A.C. Mestre,
S.P. Metur, C. Meyer, H. Meyer, W. Mi, J. Mialet-Perez, J. Miao, L. Micale, Y.
Miki, E. Milan, M. Milczarek, D.L. Miller, S.I. Miller, S. Miller, S.W. Millward,
I. Milosevic, E.A. Minina, H. Mirzaei, H.R. Mirzaei, M. Mirzaei, A. Mishra, N.
Mishra, P.K. Mishra, M. Misirkic Marjanovic, R. Misasi, A. Misra, G. Misso, C.
Mitchell, G. Mitou, T. Miura, S. Miyamoto, M. Miyazaki, M. Miyazaki, T. Miyazaki,
K. Miyazawa, N. Mizushima, T.H. Mogensen, B. Mograbi, R. Mohammadinejad, Y. Mohamud,
A. Mohanty, S. Mohapatra, T. Möhlmann, A. Mohmmed, A. Moles, K.H. Moley, M. Molinari,
V. Mollace, A.B. Møller, B. Mollereau, F. Mollinedo, C. Montagna, M.J. Monteiro,
A. Montella, L.R. Montes, B. Montico, V.K. Mony, G. Monzio Compagnoni, M.N. Moore,
M.A. Moosavi, A.L. Mora, M. Mora, D. Morales-Alamo, R. Moratalla, P.I. Moreira,
E. Morelli, S. Moreno, D. Moreno-Blas, V. Moresi, B. Morga, A.H. Morgan, F. Morin,
H. Morishita, O.L. Moritz, M. Moriyama, Y. Moriyasu, M. Morleo, E. Morselli, J.F.
Moruno-Manchon, J. Moscat, S. Mostowy, E. Motori, A.F. Moura, N. Moustaid-Moussa,
M. Mrakovcic, G. Muciño-Hernández, A. Mukherjee, S. Mukhopadhyay, J.M. Mulcahy
Levy, V. Mulero, S. Muller, C. Münch, A. Munjal, P. Munoz-Canoves, T. Muñoz-Galdeano,
C. Münz, T. Murakawa, C. Muratori, B.M. Murphy, J.P. Murphy, A. Murthy, T.T. Myöhänen,
I.U. Mysorekar, J. Mytych, S.M. Nabavi, M. Nabissi, P. Nagy, J. Nah, A. Nahimana,
I. Nakagawa, K. Nakamura, H. Nakatogawa, S.S. Nandi, M. Nanjundan, M. Nanni, G.
Napolitano, R. Nardacci, M. Narita, M. Nassif, I. Nathan, M. Natsumeda, R.J. Naude,
C. Naumann, O. Naveiras, F. Navid, S.T. Nawrocki, T.Y. Nazarko, F. Nazio, F. Negoita,
T. Neill, A.L. Neisch, L.M. Neri, M.G. Netea, P. Neubert, T.P. Neufeld, D. Neumann,
A. Neutzner, P.T. Newton, P.A. Ney, I.P. Nezis, C.C.W. Ng, T.B. Ng, H.T.T. Nguyen,
L.T. Nguyen, H.M. Ni, C. Ní Cheallaigh, Z. Ni, M.C. Nicolao, F. Nicoli, M. Nieto-Diaz,
P. Nilsson, S. Ning, R. Niranjan, H. Nishimune, M. Niso-Santano, R.A. Nixon, A.
Nobili, C. Nobrega, T. Noda, U. Nogueira-Recalde, T.M. Nolan, I. Nombela, I. Novak,
B. Novoa, T. Nozawa, N. Nukina, C. Nussbaum-Krammer, J. Nylandsted, T.R. O’Donovan,
S.M. O’Leary, E.J. O’Rourke, M.P. O’Sullivan, T.E. O’Sullivan, S. Oddo, I. Oehme,
M. Ogawa, E. Ogier-Denis, M.H. Ogmundsdottir, B. Ogretmen, G.T. Oh, S.H. Oh, Y.J.
Oh, T. Ohama, Y. Ohashi, M. Ohmuraya, V. Oikonomou, R. Ojha, K. Okamoto, H. Okazawa,
M. Oku, S. Oliván, J.M.A. Oliveira, M. Ollmann, J.A. Olzmann, S. Omari, M.B. Omary,
G. Önal, M. Ondrej, S.B. Ong, S.G. Ong, A. Onnis, J.A. Orellana, S. Orellana-Muñoz,
M.D.M. Ortega-Villaizan, X.R. Ortiz-Gonzalez, E. Ortona, H.D. Osiewacz, A.H.K.
Osman, R. Osta, M.S. Otegui, K. Otsu, C. Ott, L. Ottobrini, J.H.J. Ou, T.F. Outeiro,
I. Oynebraten, M. Ozturk, G. Pagès, S. Pahari, M. Pajares, U.B. Pajvani, R. Pal,
S. Paladino, N. Pallet, M. Palmieri, G. Palmisano, C. Palumbo, F. Pampaloni, L.
Pan, Q. Pan, W. Pan, X. Pan, G. Panasyuk, R. Pandey, U.B. Pandey, V. Pandya, F.
Paneni, S.Y. Pang, E. Panzarini, D.L. Papademetrio, E. Papaleo, D. Papinski, D.
Papp, E.C. Park, H.T. Park, J.M. Park, J.I. Park, J.T. Park, J. Park, S.C. Park,
S.Y. Park, A.H. Parola, J.B. Parys, A. Pasquier, B. Pasquier, J.F. Passos, N.
Pastore, H.H. Patel, D. Patschan, S. Pattingre, G. Pedraza-Alva, J. Pedraza-Chaverri,
Z. Pedrozo, G. Pei, J. Pei, H. Peled-Zehavi, J.M. Pellegrini, J. Pelletier, M.A.
Peñalva, D. Peng, Y. Peng, F. Penna, M. Pennuto, F. Pentimalli, C.M.F. Pereira,
G.J.S. Pereira, L.C. Pereira, L. Pereira De Almeida, N.D. Perera, Á. Pérez-Lara,
A.B. Perez-Oliva, M.E. Pérez-Pérez, P. Periyasamy, A. Perl, C. Perrotta, I. Perrotta,
R.G. Pestell, M. Petersen, I. Petrache, G. Petrovski, T. Pfirrmann, A.S. Pfister,
J.A. Philips, H. Pi, A. Picca, A.M. Pickrell, S. Picot, G.M. Pierantoni, M. Pierdominici,
P. Pierre, V. Pierrefite-Carle, K. Pierzynowska, F. Pietrocola, M. Pietruczuk,
C. Pignata, F.X. Pimentel-Muiños, M. Pinar, R.O. Pinheiro, R. Pinkas-Kramarski,
P. Pinton, K. Pircs, S. Piya, P. Pizzo, T.S. Plantinga, H.W. Platta, A. Plaza-Zabala,
M. Plomann, E.Y. Plotnikov, H. Plun-Favreau, R. Pluta, R. Pocock, S. Pöggeler,
C. Pohl, M. Poirot, A. Poletti, M. Ponpuak, H. Popelka, B. Popova, H. Porta, S.
Porte Alcon, E. Portilla-Fernandez, M. Post, M.B. Potts, J. Poulton, T. Powers,
V. Prahlad, T.K. Prajsnar, D. Praticò, R. Prencipe, M. Priault, T. Proikas-Cezanne,
V.J. Promponas, C.G. Proud, R. Puertollano, L. Puglielli, T. Pulinilkunnil, D.
Puri, R. Puri, J. Puyal, X. Qi, Y. Qi, W. Qian, L. Qiang, Y. Qiu, J. Quadrilatero,
J. Quarleri, N. Raben, H. Rabinowich, D. Ragona, M.J. Ragusa, N. Rahimi, M. Rahmati,
V. Raia, N. Raimundo, N.S. Rajasekaran, S. Ramachandra Rao, A. Rami, I. Ramírez-Pardo,
D.B. Ramsden, F. Randow, P.N. Rangarajan, D. Ranieri, H. Rao, L. Rao, R. Rao,
S. Rathore, J.A. Ratnayaka, E.A. Ratovitski, P. Ravanan, G. Ravegnini, S.K. Ray,
B. Razani, V. Rebecca, F. Reggiori, A. Régnier-Vigouroux, A.S. Reichert, D. Reigada,
J.H. Reiling, T. Rein, S. Reipert, R.S. Rekha, H. Ren, J. Ren, W. Ren, T. Renault,
G. Renga, K. Reue, K. Rewitz, B. Ribeiro De Andrade Ramos, S.A. Riazuddin, T.M.
Ribeiro-Rodrigues, J.E. Ricci, R. Ricci, V. Riccio, D.R. Richardson, Y. Rikihisa,
M.V. Risbud, R.M. Risueño, K. Ritis, S. Rizza, R. Rizzuto, H.C. Roberts, L.D.
Roberts, K.J. Robinson, M.C. Roccheri, S. Rocchi, G.G. Rodney, T. Rodrigues, V.R.
Rodrigues Silva, A. Rodriguez, R. Rodriguez-Barrueco, N. Rodriguez-Henche, H.
Rodriguez-Rocha, J. Roelofs, R.S. Rogers, V.V. Rogov, A.I. Rojo, K. Rolka, V.
Romanello, L. Romani, A. Romano, P.S. Romano, D. Romeo-Guitart, L.C. Romero, M.
Romero, J.C. Roney, C. Rongo, S. Roperto, M.T. Rosenfeldt, P. Rosenstiel, A.G.
Rosenwald, K.A. Roth, L. Roth, S. Roth, K.M.A. Rouschop, B.D. Roussel, S. Roux,
P. Rovere-Querini, A. Roy, A. Rozieres, D. Ruano, D.C. Rubinsztein, M.P. Rubtsova,
K. Ruckdeschel, C. Ruckenstuhl, E. Rudolf, R. Rudolf, A. Ruggieri, A.A. Ruparelia,
P. Rusmini, R.R. Russell, G.L. Russo, M. Russo, R. Russo, O.O. Ryabaya, K.M. Ryan,
K.Y. Ryu, M. Sabater-Arcis, U. Sachdev, M. Sacher, C. Sachse, A. Sadhu, J. Sadoshima,
N. Safren, P. Saftig, A.P. Sagona, G. Sahay, A. Sahebkar, M. Sahin, O. Sahin,
S. Sahni, N. Saito, S. Saito, T. Saito, R. Sakai, Y. Sakai, J.I. Sakamaki, K.
Saksela, G. Salazar, A. Salazar-Degracia, G.H. Salekdeh, A.K. Saluja, B. Sampaio-Marques,
M.C. Sanchez, J.A. Sanchez-Alcazar, V. Sanchez-Vera, V. Sancho-Shimizu, J.T. Sanderson,
M. Sandri, S. Santaguida, L. Santambrogio, M.M. Santana, G. Santoni, A. Sanz,
P. Sanz, S. Saran, M. Sardiello, T.J. Sargeant, A. Sarin, C. Sarkar, S. Sarkar,
M.R. Sarrias, S. Sarkar, D.T. Sarmah, J. Sarparanta, A. Sathyanarayan, R. Sathyanarayanan,
K.M. Scaglione, F. Scatozza, L. Schaefer, Z.T. Schafer, U.E. Schaible, A.H.V.
Schapira, M. Scharl, H.M. Schatzl, C.H. Schein, W. Scheper, D. Scheuring, M.V.
Schiaffino, M. Schiappacassi, R. Schindl, U. Schlattner, O. Schmidt, R. Schmitt,
S.D. Schmidt, I. Schmitz, E. Schmukler, A. Schneider, B.E. Schneider, R. Schober,
A.C. Schoijet, M.B. Schott, M. Schramm, B. Schröder, K. Schuh, C. Schüller, R.J.
Schulze, L. Schürmanns, J.C. Schwamborn, M. Schwarten, F. Scialo, S. Sciarretta,
M.J. Scott, K.W. Scotto, A.I. Scovassi, A. Scrima, A. Scrivo, D. Sebastian, S.
Sebti, S. Sedej, L. Segatori, N. Segev, P.O. Seglen, I. Seiliez, E. Seki, S.B.
Selleck, F.W. Sellke, J.T. Selsby, M. Sendtner, S. Senturk, E. Seranova, C. Sergi,
R. Serra-Moreno, H. Sesaki, C. Settembre, S.R.G. Setty, G. Sgarbi, O. Sha, J.J.
Shacka, J.A. Shah, D. Shang, C. Shao, F. Shao, S. Sharbati, L.M. Sharkey, D. Sharma,
G. Sharma, K. Sharma, P. Sharma, S. Sharma, H.M. Shen, H. Shen, J. Shen, M. Shen,
W. Shen, Z. Shen, R. Sheng, Z. Sheng, Z.H. Sheng, J. Shi, X. Shi, Y.H. Shi, K.
Shiba-Fukushima, J.J. Shieh, Y. Shimada, S. Shimizu, M. Shimozawa, T. Shintani,
C.J. Shoemaker, S. Shojaei, I. Shoji, B.V. Shravage, V. Shridhar, C.W. Shu, H.B.
Shu, K. Shui, A.K. Shukla, T.E. Shutt, V. Sica, A. Siddiqui, A. Sierra, V. Sierra-Torre,
S. Signorelli, P. Sil, B.J.D.A. Silva, J.D. Silva, E. Silva-Pavez, S. Silvente-Poirot,
R.E. Simmonds, A.K. Simon, H.U. Simon, M. Simons, A. Singh, L.P. Singh, R. Singh,
S.V. Singh, S.K. Singh, S.B. Singh, S. Singh, S.P. Singh, D. Sinha, R.A. Sinha,
S. Sinha, A. Sirko, K. Sirohi, E.L. Sivridis, P. Skendros, A. Skirycz, I. Slaninová,
S.S. Smaili, A. Smertenko, M.D. Smith, S.J. Soenen, E.J. Sohn, S.P.M. Sok, G.
Solaini, T. Soldati, S.A. Soleimanpour, R.M. Soler, A. Solovchenko, J.A. Somarelli,
A. Sonawane, F. Song, H.K. Song, J.X. Song, K. Song, Z. Song, L.R. Soria, M. Sorice,
A.A. Soukas, S.F. Soukup, D. Sousa, N. Sousa, P.A. Spagnuolo, S.A. Spector, M.M.
Srinivas Bharath, D. St. Clair, V. Stagni, L. Staiano, C.A. Stalnecker, M.V. Stankov,
P.B. Stathopulos, K. Stefan, S.M. Stefan, L. Stefanis, J.S. Steffan, A. Steinkasserer,
H. Stenmark, J. Sterneckert, C. Stevens, V. Stoka, S. Storch, B. Stork, F. Strappazzon,
A.M. Strohecker, D.G. Stupack, H. Su, L.Y. Su, L. Su, A.M. Suarez-Fontes, C.S.
Subauste, S. Subbian, P.V. Subirada, G. Sudhandiran, C.M. Sue, X. Sui, C. Summers,
G. Sun, J. Sun, K. Sun, M.X. Sun, Q. Sun, Y. Sun, Z. Sun, K.K.S. Sunahara, E.
Sundberg, K. Susztak, P. Sutovsky, H. Suzuki, G. Sweeney, J.D. Symons, S.C.W.
Sze, N.J. Szewczyk, A. Tabęcka-Łonczynska, C. Tabolacci, F. Tacke, H. Taegtmeyer,
M. Tafani, M. Tagaya, H. Tai, S.W.G. Tait, Y. Takahashi, S. Takats, P. Talwar,
C. Tam, S.Y. Tam, D. Tampellini, A. Tamura, C.T. Tan, E.K. Tan, Y.Q. Tan, M. Tanaka,
M. Tanaka, D. Tang, J. Tang, T.S. Tang, I. Tanida, Z. Tao, M. Taouis, L. Tatenhorst,
N. Tavernarakis, A. Taylor, G.A. Taylor, J.M. Taylor, E. Tchetina, A.R. Tee, I.
Tegeder, D. Teis, N. Teixeira, F. Teixeira-Clerc, K.A. Tekirdag, T. Tencomnao,
S. Tenreiro, A.V. Tepikin, P.S. Testillano, G. Tettamanti, P.L. Tharaux, K. Thedieck,
A.A. Thekkinghat, S. Thellung, J.W. Thinwa, V.P. Thirumalaikumar, S.M. Thomas,
P.G. Thomes, A. Thorburn, L. Thukral, T. Thum, M. Thumm, L. Tian, A. Tichy, A.
Till, V. Timmerman, V.I. Titorenko, S.V. Todi, K. Todorova, J.M. Toivonen, L.
Tomaipitinca, D. Tomar, C. Tomas-Zapico, S. Tomić, B.C.K. Tong, C. Tong, X. Tong,
S.A. Tooze, M.L. Torgersen, S. Torii, L. Torres-López, A. Torriglia, C.G. Towers,
R. Towns, S. Toyokuni, V. Trajkovic, D. Tramontano, Q.G. Tran, L.H. Travassos,
C.B. Trelford, S. Tremel, I.P. Trougakos, B.P. Tsao, M.P. Tschan, H.F. Tse, T.F.
Tse, H. Tsugawa, A.S. Tsvetkov, D.A. Tumbarello, Y. Tumtas, M.J. Tuñón, S. Turcotte,
B. Turk, V. Turk, B.J. Turner, R.I. Tuxworth, J.K. Tyler, E.V. Tyutereva, Y. Uchiyama,
A. Ugun-Klusek, H.H. Uhlig, M. Ułamek-Kozioł, I.V. Ulasov, M. Umekawa, C. Ungermann,
R. Unno, S. Urbe, E. Uribe-Carretero, S. Üstün, V.N. Uversky, T. Vaccari, M.I.
Vaccaro, B.F. Vahsen, H. Vakifahmetoglu-Norberg, R. Valdor, M.J. Valente, A. Valko,
R.B. Vallee, A.M. Valverde, G. Van Den Berghe, S. Van Der Veen, L. Van Kaer, J.
Van Loosdregt, S.J.L. Van Wijk, W. Vandenberghe, I. Vanhorebeek, M.A. Vannier-Santos,
N. Vannini, M.C. Vanrell, C. Vantaggiato, G. Varano, I. Varela-Nieto, M. Varga,
M.H. Vasconcelos, S. Vats, D.G. Vavvas, I. Vega-Naredo, S. Vega-Rubin-De-Celis,
G. Velasco, A.P. Velázquez, T. Vellai, E. Vellenga, F. Velotti, M. Verdier, P.
Verginis, I. Vergne, P. Verkade, M. Verma, P. Verstreken, T. Vervliet, J. Vervoorts,
A.T. Vessoni, V.M. Victor, M. Vidal, C. Vidoni, O.V. Vieira, R.D. Vierstra, S.
Viganó, H. Vihinen, V. Vijayan, M. Vila, M. Vilar, J.M. Villalba, A. Villalobo,
B. Villarejo-Zori, F. Villarroya, J. Villarroya, O. Vincent, C. Vindis, C. Viret,
M.T. Viscomi, D. Visnjic, I. Vitale, D.J. Vocadlo, O.V. Voitsekhovskaja, C. Volonté,
M. Volta, M. Vomero, C. Von Haefen, M.A. Vooijs, W. Voos, L. Vucicevic, R. Wade-Martins,
S. Waguri, K.A. Waite, S. Wakatsuki, D.W. Walker, M.J. Walker, S.A. Walker, J.
Walter, F.G. Wandosell, B. Wang, C.Y. Wang, C. Wang, C. Wang, C. Wang, C.Y. Wang,
D. Wang, F. Wang, F. Wang, F. Wang, G. Wang, H. Wang, H. Wang, H. Wang, H.G. Wang,
J. Wang, J. Wang, J. Wang, J. Wang, K. Wang, L. Wang, L. Wang, M.H. Wang, M. Wang,
N. Wang, P. Wang, P. Wang, P. Wang, P. Wang, Q.J. Wang, Q. Wang, Q.K. Wang, Q.A.
Wang, W.T. Wang, W. Wang, X. Wang, X. Wang, Y. Wang, Y. Wang, Y. Wang, Y.Y. Wang,
Y. Wang, Y. Wang, Y. Wang, Y. Wang, Z. Wang, Z. Wang, Z. Wang, G. Warnes, V. Warnsmann,
H. Watada, E. Watanabe, M. Watchon, A. Wawrzyńska, T.E. Weaver, G. Wegrzyn, A.M.
Wehman, H. Wei, L. Wei, T. Wei, Y. Wei, O.H. Weiergräber, C.C. Weihl, G. Weindl,
R. Weiskirchen, A. Wells, R.H. Wen, X. Wen, A. Werner, B. Weykopf, S.P. Wheatley,
J.L. Whitton, A.J. Whitworth, K. Wiktorska, M.E. Wildenberg, T. Wileman, S. Wilkinson,
D. Willbold, B. Williams, R.S.B. Williams, R.L. Williams, P.R. Williamson, R.A.
Wilson, B. Winner, N.J. Winsor, S.S. Witkin, H. Wodrich, U. Woehlbier, T. Wollert,
E. Wong, J.H. Wong, R.W. Wong, V.K.W. Wong, W.W.L. Wong, A.G. Wu, C. Wu, J. Wu,
J. Wu, K.K. Wu, M. Wu, S.Y. Wu, S. Wu, S.Y. Wu, S. Wu, W.K.K. Wu, X. Wu, X. Wu,
Y.W. Wu, Y. Wu, R.J. Xavier, H. Xia, L. Xia, Z. Xia, G. Xiang, J. Xiang, M. Xiang,
W. Xiang, B. Xiao, G. Xiao, H. Xiao, H.T. Xiao, J. Xiao, L. Xiao, S. Xiao, Y.
Xiao, B. Xie, C.M. Xie, M. Xie, Y. Xie, Z. Xie, Z. Xie, M. Xilouri, C. Xu, E.
Xu, H. Xu, J. Xu, J.R. Xu, L. Xu, W.W. Xu, X. Xu, Y. Xue, S.M.S. Yakhine-Diop,
M. Yamaguchi, O. Yamaguchi, A. Yamamoto, S. Yamashina, S. Yan, S.J. Yan, Z. Yan,
Y. Yanagi, C. Yang, D.S. Yang, H. Yang, H.T. Yang, H. Yang, J.M. Yang, J. Yang,
J. Yang, L. Yang, L. Yang, M. Yang, P.M. Yang, Q. Yang, S. Yang, S. Yang, S.F.
Yang, W. Yang, W.Y. Yang, X. Yang, X. Yang, Y. Yang, Y. Yang, H. Yao, S. Yao,
X. Yao, Y.G. Yao, Y.M. Yao, T. Yasui, M. Yazdankhah, P.M. Yen, C. Yi, X.M. Yin,
Y. Yin, Z. Yin, Z. Yin, M. Ying, Z. Ying, C.K. Yip, S.P.T. Yiu, Y.H. Yoo, K. Yoshida,
S.R. Yoshii, T. Yoshimori, B. Yousefi, B. Yu, H. Yu, J. Yu, J. Yu, L. Yu, M.L.
Yu, S.W. Yu, V.C. Yu, W.H. Yu, Z. Yu, Z. Yu, J. Yuan, L.Q. Yuan, S. Yuan, S.S.F.
Yuan, Y. Yuan, Z. Yuan, J. Yue, Z. Yue, J. Yun, R.L. Yung, D.N. Zacks, G. Zaffagnini,
V.O. Zambelli, I. Zanella, Q.S. Zang, S. Zanivan, S. Zappavigna, P. Zaragoza,
K.S. Zarbalis, A. Zarebkohan, A. Zarrouk, S.O. Zeitlin, J. Zeng, J.D. Zeng, E.
Žerovnik, L. Zhan, B. Zhang, D.D. Zhang, H. Zhang, H. Zhang, H. Zhang, H. Zhang,
H. Zhang, H. Zhang, H. Zhang, H.L. Zhang, J. Zhang, J. Zhang, J.P. Zhang, K.Y.B.
Zhang, L.W. Zhang, L. Zhang, L. Zhang, L. Zhang, L. Zhang, M. Zhang, P. Zhang,
S. Zhang, W. Zhang, X. Zhang, X.W. Zhang, X. Zhang, X. Zhang, X. Zhang, X. Zhang,
X.D. Zhang, Y. Zhang, Y. Zhang, Y. Zhang, Y.D. Zhang, Y. Zhang, Y.Y. Zhang, Y.
Zhang, Z. Zhang, Z. Zhang, Z. Zhang, Z. Zhang, Z. Zhang, Z. Zhang, H. Zhao, L.
Zhao, S. Zhao, T. Zhao, X.F. Zhao, Y. Zhao, Y. Zhao, Y. Zhao, Y. Zhao, G. Zheng,
K. Zheng, L. Zheng, S. Zheng, X.L. Zheng, Y. Zheng, Z.G. Zheng, B. Zhivotovsky,
Q. Zhong, A. Zhou, B. Zhou, C. Zhou, G. Zhou, H. Zhou, H. Zhou, H. Zhou, J. Zhou,
J. Zhou, J. Zhou, J. Zhou, K. Zhou, R. Zhou, X.J. Zhou, Y. Zhou, Y. Zhou, Y. Zhou,
Z.Y. Zhou, Z. Zhou, B. Zhu, C. Zhu, G.Q. Zhu, H. Zhu, H. Zhu, H. Zhu, W.G. Zhu,
Y. Zhu, Y. Zhu, H. Zhuang, X. Zhuang, K. Zientara-Rytter, C.M. Zimmermann, E.
Ziviani, T. Zoladek, W.X. Zong, D.B. Zorov, A. Zorzano, W. Zou, Z. Zou, Z. Zou,
S. Zuryn, W. Zwerschke, B. Brand-Saberi, X.C. Dong, C.S. Kenchappa, Z. Li, Y.
Lin, S. Oshima, Y. Rong, J.C. Sluimer, C.L. Stallings, C.K. Tong, Autophagy 17
(2021) 1–382.
date_created: 2021-03-28T22:01:44Z
date_published: 2021-02-08T00:00:00Z
date_updated: 2023-10-16T09:43:56Z
day: '08'
department:
- _id: JiFr
- _id: CaHe
doi: 10.1080/15548627.2020.1797280
external_id:
isi:
- '000636121800001'
pmid:
- '33634751'
intvolume: ' 17'
isi: 1
issue: '1'
language:
- iso: eng
main_file_link:
- open_access: '1'
url: https://doi.org/10.1080/15548627.2020.1797280
month: '02'
oa: 1
oa_version: Published Version
page: 1-382
pmid: 1
publication: Autophagy
publication_identifier:
eissn:
- 1554-8635
issn:
- 1554-8627
publication_status: published
publisher: Taylor & Francis
quality_controlled: '1'
scopus_import: '1'
status: public
title: Guidelines for the use and interpretation of assays for monitoring autophagy
(4th edition)
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 17
year: '2021'
...
---
_id: '9379'
abstract:
- lang: eng
text: When B cells encounter membrane-bound antigens, the formation and coalescence
of B cell antigen receptor (BCR) microclusters amplifies BCR signaling. The ability
of B cells to probe the surface of antigen-presenting cells (APCs) and respond
to APC-bound antigens requires remodeling of the actin cytoskeleton. Initial BCR
signaling stimulates actin-related protein (Arp) 2/3 complex-dependent actin polymerization,
which drives B cell spreading as well as the centripetal movement and coalescence
of BCR microclusters at the B cell-APC synapse. Sustained actin polymerization
depends on concomitant actin filament depolymerization, which enables the recycling
of actin monomers and Arp2/3 complexes. Cofilin-mediated severing of actin filaments
is a rate-limiting step in the morphological changes that occur during immune
synapse formation. Hence, regulators of cofilin activity such as WD repeat-containing
protein 1 (Wdr1), LIM domain kinase (LIMK), and coactosin-like 1 (Cotl1) may also
be essential for actin-dependent processes in B cells. Wdr1 enhances cofilin-mediated
actin disassembly. Conversely, Cotl1 competes with cofilin for binding to actin
and LIMK phosphorylates cofilin and prevents it from binding to actin filaments.
We now show that Wdr1 and LIMK have distinct roles in BCR-induced assembly of
the peripheral actin structures that drive B cell spreading, and that cofilin,
Wdr1, and LIMK all contribute to the actin-dependent amplification of BCR signaling
at the immune synapse. Depleting Cotl1 had no effect on these processes. Thus,
the Wdr1-LIMK-cofilin axis is critical for BCR-induced actin remodeling and for
B cell responses to APC-bound antigens.
acknowledgement: We thank the UBC Life Sciences Institute Imaging Facility andthe
UBC Flow Cytometry Facility.
article_number: '649433'
article_processing_charge: No
article_type: original
author:
- first_name: Madison
full_name: Bolger-Munro, Madison
id: 516F03FA-93A3-11EA-A7C5-D6BE3DDC885E
last_name: Bolger-Munro
orcid: 0000-0002-8176-4824
- first_name: Kate
full_name: Choi, Kate
last_name: Choi
- first_name: Faith
full_name: Cheung, Faith
last_name: Cheung
- first_name: Yi Tian
full_name: Liu, Yi Tian
last_name: Liu
- first_name: May
full_name: Dang-Lawson, May
last_name: Dang-Lawson
- first_name: Nikola
full_name: Deretic, Nikola
last_name: Deretic
- first_name: Connor
full_name: Keane, Connor
last_name: Keane
- first_name: Michael R.
full_name: Gold, Michael R.
last_name: Gold
citation:
ama: Bolger-Munro M, Choi K, Cheung F, et al. The Wdr1-LIMK-Cofilin axis controls
B cell antigen receptor-induced actin remodeling and signaling at the immune synapse.
Frontiers in Cell and Developmental Biology. 2021;9. doi:10.3389/fcell.2021.649433
apa: Bolger-Munro, M., Choi, K., Cheung, F., Liu, Y. T., Dang-Lawson, M., Deretic,
N., … Gold, M. R. (2021). The Wdr1-LIMK-Cofilin axis controls B cell antigen receptor-induced
actin remodeling and signaling at the immune synapse. Frontiers in Cell and
Developmental Biology. Frontiers Media. https://doi.org/10.3389/fcell.2021.649433
chicago: Bolger-Munro, Madison, Kate Choi, Faith Cheung, Yi Tian Liu, May Dang-Lawson,
Nikola Deretic, Connor Keane, and Michael R. Gold. “The Wdr1-LIMK-Cofilin Axis
Controls B Cell Antigen Receptor-Induced Actin Remodeling and Signaling at the
Immune Synapse.” Frontiers in Cell and Developmental Biology. Frontiers
Media, 2021. https://doi.org/10.3389/fcell.2021.649433.
ieee: M. Bolger-Munro et al., “The Wdr1-LIMK-Cofilin axis controls B cell
antigen receptor-induced actin remodeling and signaling at the immune synapse,”
Frontiers in Cell and Developmental Biology, vol. 9. Frontiers Media, 2021.
ista: Bolger-Munro M, Choi K, Cheung F, Liu YT, Dang-Lawson M, Deretic N, Keane
C, Gold MR. 2021. The Wdr1-LIMK-Cofilin axis controls B cell antigen receptor-induced
actin remodeling and signaling at the immune synapse. Frontiers in Cell and Developmental
Biology. 9, 649433.
mla: Bolger-Munro, Madison, et al. “The Wdr1-LIMK-Cofilin Axis Controls B Cell Antigen
Receptor-Induced Actin Remodeling and Signaling at the Immune Synapse.” Frontiers
in Cell and Developmental Biology, vol. 9, 649433, Frontiers Media, 2021,
doi:10.3389/fcell.2021.649433.
short: M. Bolger-Munro, K. Choi, F. Cheung, Y.T. Liu, M. Dang-Lawson, N. Deretic,
C. Keane, M.R. Gold, Frontiers in Cell and Developmental Biology 9 (2021).
date_created: 2021-05-09T22:01:37Z
date_published: 2021-04-13T00:00:00Z
date_updated: 2023-10-18T08:19:49Z
day: '13'
ddc:
- '570'
department:
- _id: CaHe
doi: 10.3389/fcell.2021.649433
external_id:
isi:
- '000644419500001'
pmid:
- '33928084'
file:
- access_level: open_access
checksum: 8c8a03575d2f7583f88dc3b658b0976b
content_type: application/pdf
creator: kschuh
date_created: 2021-05-11T15:09:23Z
date_updated: 2021-05-11T15:09:23Z
file_id: '9386'
file_name: 2021_Frontiers_Cell_Bolger-Munro.pdf
file_size: 4076024
relation: main_file
success: 1
file_date_updated: 2021-05-11T15:09:23Z
has_accepted_license: '1'
intvolume: ' 9'
isi: 1
keyword:
- B cell
- actin
- immune synapse
- cell spreading
- cofilin
- WDR1 (AIP1)
- LIM domain kinase
- B cell receptor (BCR)
language:
- iso: eng
month: '04'
oa: 1
oa_version: Published Version
pmid: 1
publication: Frontiers in Cell and Developmental Biology
publication_identifier:
eissn:
- 2296-634X
publication_status: published
publisher: Frontiers Media
quality_controlled: '1'
scopus_import: '1'
status: public
title: The Wdr1-LIMK-Cofilin axis controls B cell antigen receptor-induced actin remodeling
and signaling at the immune synapse
tmp:
image: /images/cc_by.png
legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
short: CC BY (4.0)
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 9
year: '2021'
...
---
_id: '9623'
abstract:
- lang: eng
text: "Cytoplasmic reorganizations are essential for morphogenesis. In large cells
like oocytes, these reorganizations become crucial in patterning the oocyte for
later stages of embryonic development. Ascidians oocytes reorganize their cytoplasm
(ooplasm) in a spectacular manner. Ooplasmic reorganization is initiated at fertilization
with the contraction of the actomyosin cortex along the animal-vegetal axis of
the oocyte, driving the accumulation of cortical endoplasmic reticulum (cER),
maternal mRNAs associated to it and a mitochondria-rich subcortical layer – the
myoplasm – in a region of the vegetal pole termed contraction pole (CP). Here
we have used the species Phallusia mammillata to investigate the changes in cell
shape that accompany these reorganizations and the mechanochemical mechanisms
underlining CP formation.\r\nWe report that the length of the animal-vegetal (AV)
axis oscillates upon fertilization: it first undergoes a cycle of fast elongation-lengthening
followed by a slow expansion of mainly the vegetal pole (VP) of the cell. We show
that the fast oscillation corresponds to a dynamic polarization of the actin cortex
as a result of a fertilization-induced increase in cortical tension in the oocyte
that triggers a rupture of the cortex at the animal pole and the establishment
of vegetal-directed cortical flows. These flows are responsible for the vegetal
accumulation of actin causing the VP to flatten. \r\nWe find that the slow expansion
of the VP, leading to CP formation, correlates with a relaxation of the vegetal
cortex and that the myoplasm plays a role in the expansion. We show that the myoplasm
is a solid-like layer that buckles under compression forces arising from the contracting
actin cortex at the VP. Straightening of the myoplasm when actin flows stops,
facilitates the expansion of the VP and the CP. Altogether, our results present
a previously unrecognized role for the myoplasm in ascidian ooplasmic segregation.
\r\n"
acknowledged_ssus:
- _id: Bio
- _id: EM-Fac
- _id: NanoFab
- _id: M-Shop
alternative_title:
- ISTA Thesis
article_processing_charge: No
author:
- first_name: Silvia
full_name: Caballero Mancebo, Silvia
id: 2F1E1758-F248-11E8-B48F-1D18A9856A87
last_name: Caballero Mancebo
orcid: 0000-0002-5223-3346
citation:
ama: Caballero Mancebo S. Fertilization-induced deformations are controlled by the
actin cortex and a mitochondria-rich subcortical layer in ascidian oocytes. 2021.
doi:10.15479/at:ista:9623
apa: Caballero Mancebo, S. (2021). Fertilization-induced deformations are controlled
by the actin cortex and a mitochondria-rich subcortical layer in ascidian oocytes.
Institute of Science and Technology Austria. https://doi.org/10.15479/at:ista:9623
chicago: Caballero Mancebo, Silvia. “Fertilization-Induced Deformations Are Controlled
by the Actin Cortex and a Mitochondria-Rich Subcortical Layer in Ascidian Oocytes.”
Institute of Science and Technology Austria, 2021. https://doi.org/10.15479/at:ista:9623.
ieee: S. Caballero Mancebo, “Fertilization-induced deformations are controlled by
the actin cortex and a mitochondria-rich subcortical layer in ascidian oocytes,”
Institute of Science and Technology Austria, 2021.
ista: Caballero Mancebo S. 2021. Fertilization-induced deformations are controlled
by the actin cortex and a mitochondria-rich subcortical layer in ascidian oocytes.
Institute of Science and Technology Austria.
mla: Caballero Mancebo, Silvia. Fertilization-Induced Deformations Are Controlled
by the Actin Cortex and a Mitochondria-Rich Subcortical Layer in Ascidian Oocytes.
Institute of Science and Technology Austria, 2021, doi:10.15479/at:ista:9623.
short: S. Caballero Mancebo, Fertilization-Induced Deformations Are Controlled by
the Actin Cortex and a Mitochondria-Rich Subcortical Layer in Ascidian Oocytes,
Institute of Science and Technology Austria, 2021.
date_created: 2021-07-01T14:50:17Z
date_published: 2021-07-01T00:00:00Z
date_updated: 2023-09-07T13:33:27Z
ddc:
- '570'
degree_awarded: PhD
department:
- _id: GradSch
- _id: CaHe
doi: 10.15479/at:ista:9623
file:
- access_level: closed
checksum: e039225a47ef32666d59bf35ddd30ecf
content_type: application/vnd.openxmlformats-officedocument.wordprocessingml.document
creator: scaballe
date_created: 2021-07-01T14:48:54Z
date_updated: 2022-07-02T22:30:06Z
embargo_to: open_access
file_id: '9624'
file_name: PhDThesis_SCM.docx
file_size: 131946790
relation: source_file
- access_level: open_access
checksum: dd4d78962ea94ad95e97ca7d9af08f4b
content_type: application/pdf
creator: scaballe
date_created: 2021-07-01T14:46:25Z
date_updated: 2022-07-02T22:30:06Z
embargo: 2022-07-01
file_id: '9625'
file_name: PhDThesis_SCM.pdf
file_size: 17094958
relation: main_file
file_date_updated: 2022-07-02T22:30:06Z
has_accepted_license: '1'
language:
- iso: eng
month: '07'
oa: 1
oa_version: Published Version
page: '111'
publication_identifier:
isbn:
- 978-3-99078-012-1
issn:
- 2663-337X
publication_status: published
publisher: Institute of Science and Technology Austria
related_material:
record:
- id: '9750'
relation: part_of_dissertation
status: public
- id: '9006'
relation: part_of_dissertation
status: public
status: public
supervisor:
- first_name: Carl-Philipp J
full_name: Heisenberg, Carl-Philipp J
id: 39427864-F248-11E8-B48F-1D18A9856A87
last_name: Heisenberg
orcid: 0000-0002-0912-4566
title: Fertilization-induced deformations are controlled by the actin cortex and a
mitochondria-rich subcortical layer in ascidian oocytes
tmp:
image: /images/cc_by_nc_nd.png
legal_code_url: https://creativecommons.org/licenses/by-nc-nd/4.0/legalcode
name: Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International
(CC BY-NC-ND 4.0)
short: CC BY-NC-ND (4.0)
type: dissertation
user_id: c635000d-4b10-11ee-a964-aac5a93f6ac1
year: '2021'
...
---
_id: '9006'
abstract:
- lang: eng
text: Cytoplasm is a gel-like crowded environment composed of various macromolecules,
organelles, cytoskeletal networks, and cytosol. The structure of the cytoplasm
is highly organized and heterogeneous due to the crowding of its constituents
and their effective compartmentalization. In such an environment, the diffusive
dynamics of the molecules are restricted, an effect that is further amplified
by clustering and anchoring of molecules. Despite the crowded nature of the cytoplasm
at the microscopic scale, large-scale reorganization of the cytoplasm is essential
for important cellular functions, such as cell division and polarization. How
such mesoscale reorganization of the cytoplasm is achieved, especially for large
cells such as oocytes or syncytial tissues that can span hundreds of micrometers
in size, is only beginning to be understood. In this review, we will discuss recent
advances in elucidating the molecular, cellular, and biophysical mechanisms by
which the cytoskeleton drives cytoplasmic reorganization across different scales,
structures, and species.
acknowledgement: We would like to thank Justine Renno for illustrations and Edouard
Hannezo and members of the Heisenberg group for their comments on previous versions
of the manuscript.
article_processing_charge: No
article_type: original
author:
- first_name: Shayan
full_name: Shamipour, Shayan
id: 40B34FE2-F248-11E8-B48F-1D18A9856A87
last_name: Shamipour
- first_name: Silvia
full_name: Caballero Mancebo, Silvia
id: 2F1E1758-F248-11E8-B48F-1D18A9856A87
last_name: Caballero Mancebo
orcid: 0000-0002-5223-3346
- first_name: Carl-Philipp J
full_name: Heisenberg, Carl-Philipp J
id: 39427864-F248-11E8-B48F-1D18A9856A87
last_name: Heisenberg
orcid: 0000-0002-0912-4566
citation:
ama: Shamipour S, Caballero Mancebo S, Heisenberg C-PJ. Cytoplasm’s got moves. Developmental
Cell. 2021;56(2):P213-226. doi:10.1016/j.devcel.2020.12.002
apa: Shamipour, S., Caballero Mancebo, S., & Heisenberg, C.-P. J. (2021). Cytoplasm’s
got moves. Developmental Cell. Elsevier. https://doi.org/10.1016/j.devcel.2020.12.002
chicago: Shamipour, Shayan, Silvia Caballero Mancebo, and Carl-Philipp J Heisenberg.
“Cytoplasm’s Got Moves.” Developmental Cell. Elsevier, 2021. https://doi.org/10.1016/j.devcel.2020.12.002.
ieee: S. Shamipour, S. Caballero Mancebo, and C.-P. J. Heisenberg, “Cytoplasm’s
got moves,” Developmental Cell, vol. 56, no. 2. Elsevier, pp. P213-226,
2021.
ista: Shamipour S, Caballero Mancebo S, Heisenberg C-PJ. 2021. Cytoplasm’s got moves.
Developmental Cell. 56(2), P213-226.
mla: Shamipour, Shayan, et al. “Cytoplasm’s Got Moves.” Developmental Cell,
vol. 56, no. 2, Elsevier, 2021, pp. P213-226, doi:10.1016/j.devcel.2020.12.002.
short: S. Shamipour, S. Caballero Mancebo, C.-P.J. Heisenberg, Developmental Cell
56 (2021) P213-226.
date_created: 2021-01-17T23:01:10Z
date_published: 2021-01-25T00:00:00Z
date_updated: 2024-03-27T23:30:18Z
day: '25'
department:
- _id: CaHe
doi: 10.1016/j.devcel.2020.12.002
external_id:
isi:
- '000613273900009'
pmid:
- '33321104'
intvolume: ' 56'
isi: 1
issue: '2'
language:
- iso: eng
main_file_link:
- open_access: '1'
url: https://doi.org/10.1016/j.devcel.2020.12.002
month: '01'
oa: 1
oa_version: Published Version
page: P213-226
pmid: 1
publication: Developmental Cell
publication_identifier:
eissn:
- '18781551'
issn:
- '15345807'
publication_status: published
publisher: Elsevier
quality_controlled: '1'
related_material:
record:
- id: '9623'
relation: dissertation_contains
status: public
scopus_import: '1'
status: public
title: Cytoplasm's got moves
type: journal_article
user_id: 4359f0d1-fa6c-11eb-b949-802e58b17ae8
volume: 56
year: '2021'
...
---
_id: '9397'
abstract:
- lang: eng
text: Accumulation of interstitial fluid (IF) between embryonic cells is a common
phenomenon in vertebrate embryogenesis. Unlike other model systems, where these
accumulations coalesce into a large central cavity – the blastocoel, in zebrafish,
IF is more uniformly distributed between the deep cells (DC) before the onset
of gastrulation. This is likely due to the presence of a large extraembryonic
structure – the yolk cell (YC) at the position where the blastocoel typically
forms in other model organisms. IF has long been speculated to play a role in
tissue morphogenesis during embryogenesis, but direct evidence supporting such
function is still sparse. Here we show that the relocalization of IF to the interface
between the YC and DC/epiblast is critical for axial mesendoderm (ME) cell protrusion
formation and migration along this interface, a key process in embryonic axis
formation. We further demonstrate that axial ME cell migration and IF relocalization
engage in a positive feedback loop, where axial ME migration triggers IF accumulation
ahead of the advancing axial ME tissue by mechanically compressing the overlying
epiblast cell layer. Upon compression, locally induced flow relocalizes the IF
through the porous epiblast tissue resulting in an IF accumulation ahead of the
leading axial ME. This IF accumulation, in turn, promotes cell protrusion formation
and migration of the leading axial ME cells, thereby facilitating axial ME extension.
Our findings reveal a central role of dynamic IF relocalization in orchestrating
germ layer morphogenesis during gastrulation.
alternative_title:
- ISTA Thesis
article_processing_charge: No
author:
- first_name: Karla
full_name: Huljev, Karla
id: 44C6F6A6-F248-11E8-B48F-1D18A9856A87
last_name: Huljev
citation:
ama: Huljev K. Coordinated spatiotemporal reorganization of interstitial fluid is
required for axial mesendoderm migration in zebrafish gastrulation. 2021. doi:10.15479/at:ista:9397
apa: Huljev, K. (2021). Coordinated spatiotemporal reorganization of interstitial
fluid is required for axial mesendoderm migration in zebrafish gastrulation.
Institute of Science and Technology Austria. https://doi.org/10.15479/at:ista:9397
chicago: Huljev, Karla. “Coordinated Spatiotemporal Reorganization of Interstitial
Fluid Is Required for Axial Mesendoderm Migration in Zebrafish Gastrulation.”
Institute of Science and Technology Austria, 2021. https://doi.org/10.15479/at:ista:9397.
ieee: K. Huljev, “Coordinated spatiotemporal reorganization of interstitial fluid
is required for axial mesendoderm migration in zebrafish gastrulation,” Institute
of Science and Technology Austria, 2021.
ista: Huljev K. 2021. Coordinated spatiotemporal reorganization of interstitial
fluid is required for axial mesendoderm migration in zebrafish gastrulation. Institute
of Science and Technology Austria.
mla: Huljev, Karla. Coordinated Spatiotemporal Reorganization of Interstitial
Fluid Is Required for Axial Mesendoderm Migration in Zebrafish Gastrulation.
Institute of Science and Technology Austria, 2021, doi:10.15479/at:ista:9397.
short: K. Huljev, Coordinated Spatiotemporal Reorganization of Interstitial Fluid
Is Required for Axial Mesendoderm Migration in Zebrafish Gastrulation, Institute
of Science and Technology Austria, 2021.
date_created: 2021-05-17T12:31:30Z
date_published: 2021-05-18T00:00:00Z
date_updated: 2023-09-07T13:32:32Z
day: '18'
ddc:
- '571'
degree_awarded: PhD
department:
- _id: CaHe
- _id: GradSch
doi: 10.15479/at:ista:9397
file:
- access_level: closed
checksum: 7f98532f5324a0b2f3fa8de2967baa19
content_type: application/vnd.openxmlformats-officedocument.wordprocessingml.document
creator: khuljev
date_created: 2021-05-17T12:29:12Z
date_updated: 2022-05-21T22:30:04Z
embargo_to: open_access
file_id: '9398'
file_name: KHuljev_Thesis_corrections.docx
file_size: 47799741
relation: source_file
- access_level: open_access
checksum: bf512f8a1e572a543778fc4b227c01ba
content_type: application/pdf
creator: khuljev
date_created: 2021-05-18T14:50:28Z
date_updated: 2022-05-21T22:30:04Z
embargo: 2022-05-20
file_id: '9401'
file_name: new_KHuljev_Thesis_corrections.pdf
file_size: 16542131
relation: main_file
file_date_updated: 2022-05-21T22:30:04Z
has_accepted_license: '1'
language:
- iso: eng
month: '05'
oa: 1
oa_version: Published Version
page: '101'
publication_identifier:
issn:
- 2663-337X
publication_status: published
publisher: Institute of Science and Technology Austria
status: public
supervisor:
- first_name: Carl-Philipp J
full_name: Heisenberg, Carl-Philipp J
id: 39427864-F248-11E8-B48F-1D18A9856A87
last_name: Heisenberg
orcid: 0000-0002-0912-4566
title: Coordinated spatiotemporal reorganization of interstitial fluid is required
for axial mesendoderm migration in zebrafish gastrulation
type: dissertation
user_id: c635000d-4b10-11ee-a964-aac5a93f6ac1
year: '2021'
...
---
_id: '7888'
abstract:
- lang: eng
text: Embryonic stem cell cultures are thought to self-organize into embryoid bodies,
able to undergo symmetry-breaking, germ layer specification and even morphogenesis.
Yet, it is unclear how to reconcile this remarkable self-organization capacity
with classical experiments demonstrating key roles for extrinsic biases by maternal
factors and/or extraembryonic tissues in embryogenesis. Here, we show that zebrafish
embryonic tissue explants, prepared prior to germ layer induction and lacking
extraembryonic tissues, can specify all germ layers and form a seemingly complete
mesendoderm anlage. Importantly, explant organization requires polarized inheritance
of maternal factors from dorsal-marginal regions of the blastoderm. Moreover,
induction of endoderm and head-mesoderm, which require peak Nodal-signaling levels,
is highly variable in explants, reminiscent of embryos with reduced Nodal signals
from the extraembryonic tissues. Together, these data suggest that zebrafish explants
do not undergo bona fide self-organization, but rather display features of genetically
encoded self-assembly, where intrinsic genetic programs control the emergence
of order.
article_number: e55190
article_processing_charge: No
article_type: original
author:
- first_name: Alexandra
full_name: Schauer, Alexandra
id: 30A536BA-F248-11E8-B48F-1D18A9856A87
last_name: Schauer
orcid: 0000-0001-7659-9142
- first_name: Diana C
full_name: Nunes Pinheiro, Diana C
id: 2E839F16-F248-11E8-B48F-1D18A9856A87
last_name: Nunes Pinheiro
orcid: 0000-0003-4333-7503
- first_name: Robert
full_name: Hauschild, Robert
id: 4E01D6B4-F248-11E8-B48F-1D18A9856A87
last_name: Hauschild
orcid: 0000-0001-9843-3522
- first_name: Carl-Philipp J
full_name: Heisenberg, Carl-Philipp J
id: 39427864-F248-11E8-B48F-1D18A9856A87
last_name: Heisenberg
orcid: 0000-0002-0912-4566
citation:
ama: Schauer A, Nunes Pinheiro DC, Hauschild R, Heisenberg C-PJ. Zebrafish embryonic
explants undergo genetically encoded self-assembly. eLife. 2020;9. doi:10.7554/elife.55190
apa: Schauer, A., Nunes Pinheiro, D. C., Hauschild, R., & Heisenberg, C.-P.
J. (2020). Zebrafish embryonic explants undergo genetically encoded self-assembly.
ELife. eLife Sciences Publications. https://doi.org/10.7554/elife.55190
chicago: Schauer, Alexandra, Diana C Nunes Pinheiro, Robert Hauschild, and Carl-Philipp
J Heisenberg. “Zebrafish Embryonic Explants Undergo Genetically Encoded Self-Assembly.”
ELife. eLife Sciences Publications, 2020. https://doi.org/10.7554/elife.55190.
ieee: A. Schauer, D. C. Nunes Pinheiro, R. Hauschild, and C.-P. J. Heisenberg, “Zebrafish
embryonic explants undergo genetically encoded self-assembly,” eLife, vol.
9. eLife Sciences Publications, 2020.
ista: Schauer A, Nunes Pinheiro DC, Hauschild R, Heisenberg C-PJ. 2020. Zebrafish
embryonic explants undergo genetically encoded self-assembly. eLife. 9, e55190.
mla: Schauer, Alexandra, et al. “Zebrafish Embryonic Explants Undergo Genetically
Encoded Self-Assembly.” ELife, vol. 9, e55190, eLife Sciences Publications,
2020, doi:10.7554/elife.55190.
short: A. Schauer, D.C. Nunes Pinheiro, R. Hauschild, C.-P.J. Heisenberg, ELife
9 (2020).
date_created: 2020-05-25T15:01:40Z
date_published: 2020-04-06T00:00:00Z
date_updated: 2023-08-21T06:25:49Z
day: '06'
ddc:
- '570'
department:
- _id: CaHe
- _id: Bio
doi: 10.7554/elife.55190
ec_funded: 1
external_id:
isi:
- '000531544400001'
pmid:
- '32250246'
file:
- access_level: open_access
checksum: f6aad884cf706846ae9357fcd728f8b5
content_type: application/pdf
creator: dernst
date_created: 2020-05-25T15:15:43Z
date_updated: 2020-07-14T12:48:04Z
file_id: '7890'
file_name: 2020_eLife_Schauer.pdf
file_size: 7744848
relation: main_file
file_date_updated: 2020-07-14T12:48:04Z
has_accepted_license: '1'
intvolume: ' 9'
isi: 1
language:
- iso: eng
month: '04'
oa: 1
oa_version: Published Version
pmid: 1
project:
- _id: 260F1432-B435-11E9-9278-68D0E5697425
call_identifier: H2020
grant_number: '742573'
name: Interaction and feedback between cell mechanics and fate specification in
vertebrate gastrulation
- _id: 26B1E39C-B435-11E9-9278-68D0E5697425
grant_number: '25239'
name: 'Mesendoderm specification in zebrafish: The role of extraembryonic tissues'
- _id: 26520D1E-B435-11E9-9278-68D0E5697425
grant_number: ALTF 850-2017
name: Coordination of mesendoderm cell fate specification and internalization during
zebrafish gastrulation
- _id: 266BC5CE-B435-11E9-9278-68D0E5697425
grant_number: LT000429
name: Coordination of mesendoderm fate specification and internalization during
zebrafish gastrulation
publication: eLife
publication_identifier:
issn:
- 2050-084X
publication_status: published
publisher: eLife Sciences Publications
quality_controlled: '1'
related_material:
record:
- id: '12891'
relation: dissertation_contains
status: public
scopus_import: '1'
status: public
title: Zebrafish embryonic explants undergo genetically encoded self-assembly
tmp:
image: /images/cc_by.png
legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
short: CC BY (4.0)
type: journal_article
user_id: 4359f0d1-fa6c-11eb-b949-802e58b17ae8
volume: 9
year: '2020'
...
---
_id: '8680'
abstract:
- lang: eng
text: Animal development entails the organization of specific cell types in space
and time, and spatial patterns must form in a robust manner. In the zebrafish
spinal cord, neural progenitors form stereotypic patterns despite noisy morphogen
signaling and large-scale cellular rearrangements during morphogenesis and growth.
By directly measuring adhesion forces and preferences for three types of endogenous
neural progenitors, we provide evidence for the differential adhesion model in
which differences in intercellular adhesion mediate cell sorting. Cell type–specific
combinatorial expression of different classes of cadherins (N-cadherin, cadherin
11, and protocadherin 19) results in homotypic preference ex vivo and patterning
robustness in vivo. Furthermore, the differential adhesion code is regulated by
the sonic hedgehog morphogen gradient. We propose that robust patterning during
tissue morphogenesis results from interplay between adhesion-based self-organization
and morphogen-directed patterning.
acknowledgement: "We thank the members of the Megason and Heisenberg labs for critical
discussions of and technical assistance during the work and B. Appel, S. Holley,
J. Jontes, and D. Gilmour for transgenic fish. This work is supported by the Damon
Runyon Cancer Foundation, a NICHD K99 fellowship (1K99HD092623), a Travelling Fellowship
of the Company of Biologists, a Collaborative Research grant from the Burroughs
Wellcome Foundation (T.Y.-C.T.), NIH grant 01GM107733 (T.Y.-C.T. and S.G.M.), NIH
grant R01NS102322 (T.C.-C. and H.K.), and an ERC advanced grant\r\n(MECSPEC) (C.-P.H.)."
article_processing_charge: No
article_type: original
author:
- first_name: Tony Y.-C.
full_name: Tsai, Tony Y.-C.
last_name: Tsai
- first_name: Mateusz K
full_name: Sikora, Mateusz K
id: 2F74BCDE-F248-11E8-B48F-1D18A9856A87
last_name: Sikora
- first_name: Peng
full_name: Xia, Peng
id: 4AB6C7D0-F248-11E8-B48F-1D18A9856A87
last_name: Xia
orcid: 0000-0002-5419-7756
- first_name: Tugba
full_name: Colak-Champollion, Tugba
last_name: Colak-Champollion
- first_name: Holger
full_name: Knaut, Holger
last_name: Knaut
- first_name: Carl-Philipp J
full_name: Heisenberg, Carl-Philipp J
id: 39427864-F248-11E8-B48F-1D18A9856A87
last_name: Heisenberg
orcid: 0000-0002-0912-4566
- first_name: Sean G.
full_name: Megason, Sean G.
last_name: Megason
citation:
ama: Tsai TY-C, Sikora MK, Xia P, et al. An adhesion code ensures robust pattern
formation during tissue morphogenesis. Science. 2020;370(6512):113-116.
doi:10.1126/science.aba6637
apa: Tsai, T. Y.-C., Sikora, M. K., Xia, P., Colak-Champollion, T., Knaut, H., Heisenberg,
C.-P. J., & Megason, S. G. (2020). An adhesion code ensures robust pattern
formation during tissue morphogenesis. Science. American Association for
the Advancement of Science. https://doi.org/10.1126/science.aba6637
chicago: Tsai, Tony Y.-C., Mateusz K Sikora, Peng Xia, Tugba Colak-Champollion,
Holger Knaut, Carl-Philipp J Heisenberg, and Sean G. Megason. “An Adhesion Code
Ensures Robust Pattern Formation during Tissue Morphogenesis.” Science.
American Association for the Advancement of Science, 2020. https://doi.org/10.1126/science.aba6637.
ieee: T. Y.-C. Tsai et al., “An adhesion code ensures robust pattern formation
during tissue morphogenesis,” Science, vol. 370, no. 6512. American Association
for the Advancement of Science, pp. 113–116, 2020.
ista: Tsai TY-C, Sikora MK, Xia P, Colak-Champollion T, Knaut H, Heisenberg C-PJ,
Megason SG. 2020. An adhesion code ensures robust pattern formation during tissue
morphogenesis. Science. 370(6512), 113–116.
mla: Tsai, Tony Y. C., et al. “An Adhesion Code Ensures Robust Pattern Formation
during Tissue Morphogenesis.” Science, vol. 370, no. 6512, American Association
for the Advancement of Science, 2020, pp. 113–16, doi:10.1126/science.aba6637.
short: T.Y.-C. Tsai, M.K. Sikora, P. Xia, T. Colak-Champollion, H. Knaut, C.-P.J.
Heisenberg, S.G. Megason, Science 370 (2020) 113–116.
date_created: 2020-10-19T14:09:38Z
date_published: 2020-10-02T00:00:00Z
date_updated: 2023-08-22T10:36:35Z
day: '02'
department:
- _id: CaHe
doi: 10.1126/science.aba6637
ec_funded: 1
external_id:
isi:
- '000579169000053'
intvolume: ' 370'
isi: 1
issue: '6512'
keyword:
- Multidisciplinary
language:
- iso: eng
main_file_link:
- open_access: '1'
url: https://www.biorxiv.org/content/10.1101/803635v1
month: '10'
oa: 1
oa_version: Preprint
page: 113-116
project:
- _id: 260F1432-B435-11E9-9278-68D0E5697425
call_identifier: H2020
grant_number: '742573'
name: Interaction and feedback between cell mechanics and fate specification in
vertebrate gastrulation
publication: Science
publication_identifier:
eissn:
- 1095-9203
issn:
- 0036-8075
publication_status: published
publisher: American Association for the Advancement of Science
quality_controlled: '1'
related_material:
link:
- description: News on IST Homepage
relation: press_release
url: https://ist.ac.at/en/news/sticking-together/
scopus_import: '1'
status: public
title: An adhesion code ensures robust pattern formation during tissue morphogenesis
type: journal_article
user_id: 4359f0d1-fa6c-11eb-b949-802e58b17ae8
volume: 370
year: '2020'
...
---
_id: '8957'
abstract:
- lang: eng
text: Global tissue tension anisotropy has been shown to trigger stereotypical cell
division orientation by elongating mitotic cells along the main tension axis.
Yet, how tissue tension elongates mitotic cells despite those cells undergoing
mitotic rounding (MR) by globally upregulating cortical actomyosin tension remains
unclear. We addressed this question by taking advantage of ascidian embryos, consisting
of a small number of interphasic and mitotic blastomeres and displaying an invariant
division pattern. We found that blastomeres undergo MR by locally relaxing cortical
tension at their apex, thereby allowing extrinsic pulling forces from neighboring
interphasic blastomeres to polarize their shape and thus division orientation.
Consistently, interfering with extrinsic forces by reducing the contractility
of interphasic blastomeres or disrupting the establishment of asynchronous mitotic
domains leads to aberrant mitotic cell division orientations. Thus, apical relaxation
during MR constitutes a key mechanism by which tissue tension anisotropy controls
stereotypical cell division orientation.
acknowledged_ssus:
- _id: Bio
- _id: NanoFab
acknowledgement: 'We thank members of the Heisenberg and McDougall groups for technical
advice and discussion, Hitoyoshi Yasuo for sharing lab equipment, Lucas Leclère
and Hitoyoshi Yasuo for their comments on a preliminary version of the manuscript,
and Philippe Dru for the Rose plots. We are grateful to the Bioimaging and Nanofabrication
facilities of IST Austria and the Imaging Platform (PIM) and animal facility (CRB)
of Institut de la Mer de Villefranche (IMEV), which is supported by EMBRC-France,
whose French state funds are managed by the ANR within the Investments of the Future
program under reference ANR-10-INBS-0, for continuous support. This work was supported
by a grant from the French Government funding agency Agence National de la Recherche
(ANR “MorCell”: ANR-17-CE 13-002 8).'
article_processing_charge: No
article_type: original
author:
- first_name: Benoit G
full_name: Godard, Benoit G
id: 33280250-F248-11E8-B48F-1D18A9856A87
last_name: Godard
- first_name: Rémi
full_name: Dumollard, Rémi
last_name: Dumollard
- first_name: Edwin
full_name: Munro, Edwin
last_name: Munro
- first_name: Janet
full_name: Chenevert, Janet
last_name: Chenevert
- first_name: Céline
full_name: Hebras, Céline
last_name: Hebras
- first_name: Alex
full_name: Mcdougall, Alex
last_name: Mcdougall
- first_name: Carl-Philipp J
full_name: Heisenberg, Carl-Philipp J
id: 39427864-F248-11E8-B48F-1D18A9856A87
last_name: Heisenberg
orcid: 0000-0002-0912-4566
citation:
ama: Godard BG, Dumollard R, Munro E, et al. Apical relaxation during mitotic rounding
promotes tension-oriented cell division. Developmental Cell. 2020;55(6):695-706.
doi:10.1016/j.devcel.2020.10.016
apa: Godard, B. G., Dumollard, R., Munro, E., Chenevert, J., Hebras, C., Mcdougall,
A., & Heisenberg, C.-P. J. (2020). Apical relaxation during mitotic rounding
promotes tension-oriented cell division. Developmental Cell. Elsevier.
https://doi.org/10.1016/j.devcel.2020.10.016
chicago: Godard, Benoit G, Rémi Dumollard, Edwin Munro, Janet Chenevert, Céline
Hebras, Alex Mcdougall, and Carl-Philipp J Heisenberg. “Apical Relaxation during
Mitotic Rounding Promotes Tension-Oriented Cell Division.” Developmental Cell.
Elsevier, 2020. https://doi.org/10.1016/j.devcel.2020.10.016.
ieee: B. G. Godard et al., “Apical relaxation during mitotic rounding promotes
tension-oriented cell division,” Developmental Cell, vol. 55, no. 6. Elsevier,
pp. 695–706, 2020.
ista: Godard BG, Dumollard R, Munro E, Chenevert J, Hebras C, Mcdougall A, Heisenberg
C-PJ. 2020. Apical relaxation during mitotic rounding promotes tension-oriented
cell division. Developmental Cell. 55(6), 695–706.
mla: Godard, Benoit G., et al. “Apical Relaxation during Mitotic Rounding Promotes
Tension-Oriented Cell Division.” Developmental Cell, vol. 55, no. 6, Elsevier,
2020, pp. 695–706, doi:10.1016/j.devcel.2020.10.016.
short: B.G. Godard, R. Dumollard, E. Munro, J. Chenevert, C. Hebras, A. Mcdougall,
C.-P.J. Heisenberg, Developmental Cell 55 (2020) 695–706.
date_created: 2020-12-20T23:01:19Z
date_published: 2020-12-21T00:00:00Z
date_updated: 2023-08-24T11:01:22Z
day: '21'
department:
- _id: CaHe
doi: 10.1016/j.devcel.2020.10.016
external_id:
isi:
- '000600665700008'
pmid:
- '33207225'
intvolume: ' 55'
isi: 1
issue: '6'
language:
- iso: eng
month: '12'
oa_version: None
page: 695-706
pmid: 1
publication: Developmental Cell
publication_identifier:
eissn:
- '18781551'
issn:
- '15345807'
publication_status: published
publisher: Elsevier
quality_controlled: '1'
related_material:
link:
- description: News on IST Homepage
relation: press_release
url: https://ist.ac.at/en/news/relaxing-cell-divisions/
scopus_import: '1'
status: public
title: Apical relaxation during mitotic rounding promotes tension-oriented cell division
type: journal_article
user_id: 4359f0d1-fa6c-11eb-b949-802e58b17ae8
volume: 55
year: '2020'
...
---
_id: '7227'
abstract:
- lang: eng
text: Gastrulation entails specification and formation of three embryonic germ layers—ectoderm,
mesoderm and endoderm—thereby establishing the basis for the future body plan.
In zebrafish embryos, germ layer specification occurs during blastula and early
gastrula stages (Ho & Kimmel, 1993), a period when the main morphogenetic movements
underlying gastrulation are initiated. Hence, the signals driving progenitor cell
fate specification, such as Nodal ligands from the TGF-β family, also play key
roles in regulating germ layer progenitor cell segregation (Carmany-Rampey & Schier,
2001; David & Rosa, 2001; Feldman et al., 2000; Gritsman et al., 1999; Keller
et al., 2008). In this review, we summarize and discuss the main signaling pathways
involved in germ layer progenitor cell fate specification and segregation, specifically
focusing on recent advances in understanding the interplay between mesoderm and
endoderm specification and the internalization movements at the onset of zebrafish
gastrulation.
acknowledgement: We thank Alexandra Schauer, Nicoletta Petridou and Feyza Nur Arslan
for comments on the manuscript. Research in the Heisenberg laboratory is supported
by an ERC Advanced Grant (MECSPEC 742573), ANR/FWF (I03601) and FWF/DFG (I03196)
International Cooperation Grants. D. Pinheiro acknowledges a fellowship from EMBO
ALTF (850-2017) and is currently supported by HFSP LTF (LT000429/2018-L2).
alternative_title:
- Current Topics in Developmental Biology
article_processing_charge: No
author:
- first_name: Diana C
full_name: Nunes Pinheiro, Diana C
id: 2E839F16-F248-11E8-B48F-1D18A9856A87
last_name: Nunes Pinheiro
orcid: 0000-0003-4333-7503
- first_name: Carl-Philipp J
full_name: Heisenberg, Carl-Philipp J
id: 39427864-F248-11E8-B48F-1D18A9856A87
last_name: Heisenberg
orcid: 0000-0002-0912-4566
citation:
ama: 'Nunes Pinheiro DC, Heisenberg C-PJ. Zebrafish gastrulation: Putting fate in
motion. In: Gastrulation: From Embryonic Pattern to Form. Vol 136. Elsevier;
2020:343-375. doi:10.1016/bs.ctdb.2019.10.009'
apa: 'Nunes Pinheiro, D. C., & Heisenberg, C.-P. J. (2020). Zebrafish gastrulation:
Putting fate in motion. In Gastrulation: From Embryonic Pattern to Form
(Vol. 136, pp. 343–375). Elsevier. https://doi.org/10.1016/bs.ctdb.2019.10.009'
chicago: 'Nunes Pinheiro, Diana C, and Carl-Philipp J Heisenberg. “Zebrafish Gastrulation:
Putting Fate in Motion.” In Gastrulation: From Embryonic Pattern to Form,
136:343–75. Elsevier, 2020. https://doi.org/10.1016/bs.ctdb.2019.10.009.'
ieee: 'D. C. Nunes Pinheiro and C.-P. J. Heisenberg, “Zebrafish gastrulation: Putting
fate in motion,” in Gastrulation: From Embryonic Pattern to Form, vol.
136, Elsevier, 2020, pp. 343–375.'
ista: 'Nunes Pinheiro DC, Heisenberg C-PJ. 2020.Zebrafish gastrulation: Putting
fate in motion. In: Gastrulation: From Embryonic Pattern to Form. Current Topics
in Developmental Biology, vol. 136, 343–375.'
mla: 'Nunes Pinheiro, Diana C., and Carl-Philipp J. Heisenberg. “Zebrafish Gastrulation:
Putting Fate in Motion.” Gastrulation: From Embryonic Pattern to Form,
vol. 136, Elsevier, 2020, pp. 343–75, doi:10.1016/bs.ctdb.2019.10.009.'
short: 'D.C. Nunes Pinheiro, C.-P.J. Heisenberg, in:, Gastrulation: From Embryonic
Pattern to Form, Elsevier, 2020, pp. 343–375.'
date_created: 2020-01-05T23:00:46Z
date_published: 2020-06-01T00:00:00Z
date_updated: 2023-09-06T14:54:36Z
day: '01'
department:
- _id: CaHe
doi: 10.1016/bs.ctdb.2019.10.009
ec_funded: 1
external_id:
isi:
- '000611830600013'
pmid:
- '31959295'
intvolume: ' 136'
isi: 1
language:
- iso: eng
month: '06'
oa_version: None
page: 343-375
pmid: 1
project:
- _id: 260F1432-B435-11E9-9278-68D0E5697425
call_identifier: H2020
grant_number: '742573'
name: Interaction and feedback between cell mechanics and fate specification in
vertebrate gastrulation
- _id: 2646861A-B435-11E9-9278-68D0E5697425
call_identifier: FWF
grant_number: I03601
name: Control of embryonic cleavage pattern
- _id: 2608FC64-B435-11E9-9278-68D0E5697425
call_identifier: FWF
grant_number: I03196
name: Control of epithelial cell layer spreading in zebrafish
- _id: 266BC5CE-B435-11E9-9278-68D0E5697425
grant_number: LT000429
name: Coordination of mesendoderm fate specification and internalization during
zebrafish gastrulation
- _id: 26520D1E-B435-11E9-9278-68D0E5697425
grant_number: ALTF 850-2017
name: Coordination of mesendoderm cell fate specification and internalization during
zebrafish gastrulation
publication: 'Gastrulation: From Embryonic Pattern to Form'
publication_identifier:
issn:
- '00702153'
publication_status: published
publisher: Elsevier
quality_controlled: '1'
scopus_import: '1'
status: public
title: 'Zebrafish gastrulation: Putting fate in motion'
type: book_chapter
user_id: c635000d-4b10-11ee-a964-aac5a93f6ac1
volume: 136
year: '2020'
...
---
_id: '7410'
abstract:
- lang: eng
text: 'Epiboly is a conserved gastrulation movement describing the thinning and
spreading of a sheet or multi-layer of cells. The zebrafish embryo has emerged
as a vital model system to address the cellular and molecular mechanisms that
drive epiboly. In the zebrafish embryo, the blastoderm, consisting of a simple
squamous epithelium (the enveloping layer) and an underlying mass of deep cells,
as well as a yolk nuclear syncytium (the yolk syncytial layer) undergo epiboly
to internalize the yolk cell during gastrulation. The major events during zebrafish
epiboly are: expansion of the enveloping layer and the internal yolk syncytial
layer, reduction and removal of the yolk membrane ahead of the advancing blastoderm
margin and deep cell rearrangements between the enveloping layer and yolk syncytial
layer to thin the blastoderm. Here, work addressing the cellular and molecular
mechanisms as well as the sources of the mechanical forces that underlie these
events is reviewed. The contribution of recent findings to the current model of
epiboly as well as open questions and future prospects are also discussed.'
article_processing_charge: No
author:
- first_name: Ashley E.E.
full_name: Bruce, Ashley E.E.
last_name: Bruce
- first_name: Carl-Philipp J
full_name: Heisenberg, Carl-Philipp J
id: 39427864-F248-11E8-B48F-1D18A9856A87
last_name: Heisenberg
orcid: 0000-0002-0912-4566
citation:
ama: 'Bruce AEE, Heisenberg C-PJ. Mechanisms of zebrafish epiboly: A current view.
In: Solnica-Krezel L, ed. Gastrulation: From Embryonic Pattern to Form.
Vol 136. Current Topics in Developmental Biology. Elsevier; 2020:319-341. doi:10.1016/bs.ctdb.2019.07.001'
apa: 'Bruce, A. E. E., & Heisenberg, C.-P. J. (2020). Mechanisms of zebrafish
epiboly: A current view. In L. Solnica-Krezel (Ed.), Gastrulation: From Embryonic
Pattern to Form (Vol. 136, pp. 319–341). Elsevier. https://doi.org/10.1016/bs.ctdb.2019.07.001'
chicago: 'Bruce, Ashley E.E., and Carl-Philipp J Heisenberg. “Mechanisms of Zebrafish
Epiboly: A Current View.” In Gastrulation: From Embryonic Pattern to Form,
edited by Lilianna Solnica-Krezel, 136:319–41. Current Topics in Developmental
Biology. Elsevier, 2020. https://doi.org/10.1016/bs.ctdb.2019.07.001.'
ieee: 'A. E. E. Bruce and C.-P. J. Heisenberg, “Mechanisms of zebrafish epiboly:
A current view,” in Gastrulation: From Embryonic Pattern to Form, vol.
136, L. Solnica-Krezel, Ed. Elsevier, 2020, pp. 319–341.'
ista: 'Bruce AEE, Heisenberg C-PJ. 2020.Mechanisms of zebrafish epiboly: A current
view. In: Gastrulation: From Embryonic Pattern to Form. vol. 136, 319–341.'
mla: 'Bruce, Ashley E. E., and Carl-Philipp J. Heisenberg. “Mechanisms of Zebrafish
Epiboly: A Current View.” Gastrulation: From Embryonic Pattern to Form,
edited by Lilianna Solnica-Krezel, vol. 136, Elsevier, 2020, pp. 319–41, doi:10.1016/bs.ctdb.2019.07.001.'
short: 'A.E.E. Bruce, C.-P.J. Heisenberg, in:, L. Solnica-Krezel (Ed.), Gastrulation:
From Embryonic Pattern to Form, Elsevier, 2020, pp. 319–341.'
date_created: 2020-01-30T09:24:06Z
date_published: 2020-01-01T00:00:00Z
date_updated: 2024-02-22T13:23:09Z
day: '01'
department:
- _id: CaHe
doi: 10.1016/bs.ctdb.2019.07.001
editor:
- first_name: 'Lilianna '
full_name: 'Solnica-Krezel, Lilianna '
last_name: Solnica-Krezel
external_id:
isi:
- '000611830600012'
intvolume: ' 136'
isi: 1
language:
- iso: eng
month: '01'
oa_version: None
page: 319-341
publication: 'Gastrulation: From Embryonic Pattern to Form'
publication_identifier:
isbn:
- '9780128127988'
issn:
- 0070-2153
publication_status: published
publisher: Elsevier
quality_controlled: '1'
scopus_import: '1'
series_title: Current Topics in Developmental Biology
status: public
title: 'Mechanisms of zebrafish epiboly: A current view'
type: book_chapter
user_id: 3E5EF7F0-F248-11E8-B48F-1D18A9856A87
volume: 136
year: '2020'
...
---
_id: '9750'
abstract:
- lang: eng
text: Tension of the actomyosin cell cortex plays a key role in determining cell-cell
contact growth and size. The level of cortical tension outside of the cell-cell
contact, when pulling at the contact edge, scales with the total size to which
a cell-cell contact can grow1,2. Here we show in zebrafish primary germ layer
progenitor cells that this monotonic relationship only applies to a narrow range
of cortical tension increase, and that above a critical threshold, contact size
inversely scales with cortical tension. This switch from cortical tension increasing
to decreasing progenitor cell-cell contact size is caused by cortical tension
promoting E-cadherin anchoring to the actomyosin cytoskeleton, thereby increasing
clustering and stability of E-cadherin at the contact. Once tension-mediated E-cadherin
stabilization at the contact exceeds a critical threshold level, the rate by which
the contact expands in response to pulling forces from the cortex sharply drops,
leading to smaller contacts at physiologically relevant timescales of contact
formation. Thus, the activity of cortical tension in expanding cell-cell contact
size is limited by tension stabilizing E-cadherin-actin complexes at the contact.
acknowledged_ssus:
- _id: Bio
- _id: EM-Fac
- _id: SSU
acknowledgement: We would like to thank Edouard Hannezo for discussions, Shayan Shami
Pour and Daniel Capek for help with data analysis, Vanessa Barone and other members
of the Heisenberg laboratory for thoughtful discussions and comments on the manuscript.
We also thank Jack Merrin for preparing the microwells, and the Scientific Service
Units at IST Austria, specifically Bioimaging and Electron Microscopy, and the Zebrafish
Facility for continuous support. We acknowledge Hitoshi Morita for the kind gift
of VinculinB-GFP plasmid. This research was supported by an ERC Advanced Grant (MECSPEC)
to C.-P.H, EMBO Long Term grant (ALTF 187-2013) to M.S and IST Fellow Marie-Curie
COFUND No. P_IST_EU01 to J.S.
article_processing_charge: No
author:
- first_name: Jana
full_name: Slovakova, Jana
id: 30F3F2F0-F248-11E8-B48F-1D18A9856A87
last_name: Slovakova
- first_name: Mateusz K
full_name: Sikora, Mateusz K
id: 2F74BCDE-F248-11E8-B48F-1D18A9856A87
last_name: Sikora
- first_name: Silvia
full_name: Caballero Mancebo, Silvia
id: 2F1E1758-F248-11E8-B48F-1D18A9856A87
last_name: Caballero Mancebo
orcid: 0000-0002-5223-3346
- first_name: Gabriel
full_name: Krens, Gabriel
id: 2B819732-F248-11E8-B48F-1D18A9856A87
last_name: Krens
orcid: 0000-0003-4761-5996
- first_name: Walter
full_name: Kaufmann, Walter
id: 3F99E422-F248-11E8-B48F-1D18A9856A87
last_name: Kaufmann
orcid: 0000-0001-9735-5315
- first_name: Karla
full_name: Huljev, Karla
id: 44C6F6A6-F248-11E8-B48F-1D18A9856A87
last_name: Huljev
- first_name: Carl-Philipp J
full_name: Heisenberg, Carl-Philipp J
id: 39427864-F248-11E8-B48F-1D18A9856A87
last_name: Heisenberg
orcid: 0000-0002-0912-4566
citation:
ama: Slovakova J, Sikora MK, Caballero Mancebo S, et al. Tension-dependent stabilization
of E-cadherin limits cell-cell contact expansion. bioRxiv. 2020. doi:10.1101/2020.11.20.391284
apa: Slovakova, J., Sikora, M. K., Caballero Mancebo, S., Krens, G., Kaufmann, W.,
Huljev, K., & Heisenberg, C.-P. J. (2020). Tension-dependent stabilization
of E-cadherin limits cell-cell contact expansion. bioRxiv. Cold Spring
Harbor Laboratory. https://doi.org/10.1101/2020.11.20.391284
chicago: Slovakova, Jana, Mateusz K Sikora, Silvia Caballero Mancebo, Gabriel Krens,
Walter Kaufmann, Karla Huljev, and Carl-Philipp J Heisenberg. “Tension-Dependent
Stabilization of E-Cadherin Limits Cell-Cell Contact Expansion.” BioRxiv.
Cold Spring Harbor Laboratory, 2020. https://doi.org/10.1101/2020.11.20.391284.
ieee: J. Slovakova et al., “Tension-dependent stabilization of E-cadherin
limits cell-cell contact expansion,” bioRxiv. Cold Spring Harbor Laboratory,
2020.
ista: Slovakova J, Sikora MK, Caballero Mancebo S, Krens G, Kaufmann W, Huljev K,
Heisenberg C-PJ. 2020. Tension-dependent stabilization of E-cadherin limits cell-cell
contact expansion. bioRxiv, 10.1101/2020.11.20.391284.
mla: Slovakova, Jana, et al. “Tension-Dependent Stabilization of E-Cadherin Limits
Cell-Cell Contact Expansion.” BioRxiv, Cold Spring Harbor Laboratory, 2020,
doi:10.1101/2020.11.20.391284.
short: J. Slovakova, M.K. Sikora, S. Caballero Mancebo, G. Krens, W. Kaufmann, K.
Huljev, C.-P.J. Heisenberg, BioRxiv (2020).
date_created: 2021-07-29T11:29:50Z
date_published: 2020-11-20T00:00:00Z
date_updated: 2024-03-27T23:30:18Z
day: '20'
department:
- _id: CaHe
- _id: EM-Fac
- _id: Bio
doi: 10.1101/2020.11.20.391284
ec_funded: 1
language:
- iso: eng
main_file_link:
- open_access: '1'
url: https://doi.org/10.1101/2020.11.20.391284
month: '11'
oa: 1
oa_version: Preprint
page: '41'
project:
- _id: 25681D80-B435-11E9-9278-68D0E5697425
call_identifier: FP7
grant_number: '291734'
name: International IST Postdoc Fellowship Programme
- _id: 260F1432-B435-11E9-9278-68D0E5697425
call_identifier: H2020
grant_number: '742573'
name: Interaction and feedback between cell mechanics and fate specification in
vertebrate gastrulation
- _id: 2521E28E-B435-11E9-9278-68D0E5697425
grant_number: 187-2013
name: Modulation of adhesion function in cell-cell contact formation by cortical
tension
publication: bioRxiv
publication_status: published
publisher: Cold Spring Harbor Laboratory
related_material:
record:
- id: '10766'
relation: later_version
status: public
- id: '9623'
relation: dissertation_contains
status: public
status: public
title: Tension-dependent stabilization of E-cadherin limits cell-cell contact expansion
type: preprint
user_id: 8b945eb4-e2f2-11eb-945a-df72226e66a9
year: '2020'
...
---
_id: '8350'
abstract:
- lang: eng
text: "Cytoplasm is a gel-like crowded environment composed of tens of thousands
of macromolecules, organelles, cytoskeletal networks and cytosol. The structure
of the cytoplasm is thought to be highly organized and heterogeneous due to the
crowding of its constituents and their effective compartmentalization. In such
an environment, the diffusive dynamics of the molecules is very restricted, an
effect that is further amplified by clustering and anchoring of molecules. Despite
the jammed nature of the cytoplasm at the microscopic scale, large-scale reorganization
of cytoplasm is essential for important cellular functions, such as nuclear positioning
and cell division. How such mesoscale reorganization of the cytoplasm is achieved,
especially for very large cells such as oocytes or syncytial tissues that can
span hundreds of micrometers in size, has only begun to be understood.\r\nIn this
thesis, I focus on the recent advances in elucidating the molecular, cellular
and biophysical principles underlying cytoplasmic organization across different
scales, structures and species. First, I outline which of these principles have
been identified by reductionist approaches, such as in vitro reconstitution assays,
where boundary conditions and components can be modulated at ease. I then describe
how the theoretical and experimental framework established in these reduced systems
have been applied to their more complex in vivo counterparts, in particular oocytes
and embryonic syncytial structures, and discuss how such complex biological systems
can initiate symmetry breaking and establish patterning.\r\nSpecifically, I examine
an example of large-scale reorganizations taking place in zebrafish embryos, where
extensive cytoplasmic streaming leads to the segregation of cytoplasm from yolk
granules along the animal-vegetal axis of the embryo. Using biophysical experimentation
and theory, I investigate the forces underlying this process, to show that this
process does not rely on cortical actin reorganization, as previously thought,
but instead on a cell-cycle-dependent bulk actin polymerization wave traveling
from the animal to the vegetal pole of the embryo. This wave functions in segregation
by both pulling cytoplasm animally and pushing yolk granules vegetally. Cytoplasm
pulling is mediated by bulk actin network flows exerting friction forces on the
cytoplasm, while yolk granule pushing is achieved by a mechanism closely resembling
actin comet formation on yolk granules. This study defines a novel role of bulk
actin polymerization waves in embryo polarization via cytoplasmic segregation.
Lastly, I describe the cytoplasmic reorganizations taking place during zebrafish
oocyte maturation, where the initial segregation of the cytoplasm and yolk granules
occurs. Here, I demonstrate a previously uncharacterized wave of microtubule aster
formation, traveling the oocyte along the animal-vegetal axis. Further research
is required to determine the role of such microtubule structures in cytoplasmic
reorganizations therein.\r\nCollectively, these studies provide further evidence
for the coupling between cell cytoskeleton and cell cycle machinery, which can
underlie a core self-organizing mechanism for orchestrating large-scale reorganizations
in a cell-cycle-tunable manner, where the modulations of the force-generating
machinery and cytoplasmic mechanics can be harbored to fulfill cellular functions."
acknowledged_ssus:
- _id: PreCl
- _id: Bio
- _id: EM-Fac
acknowledgement: "I would have had no fish and hence no results without our wonderful
fish facility crew, Verena Mayer, Eva Schlegl, Andreas Mlak and Matthias Nowak.
Special thanks to Verena for being always happy to help and dealing with our chaotic
schedules in the lab. Danke auch, Verena, für deine Geduld, mit mir auf Deutsch
zu sprechen. Das hat mir sehr geholfen.\r\nSpecial thanks to the Bioimaging and
EM facilities at IST Austria for supporting us every day. Very special thanks would
go to Robert Hauschild for his continuous support on data analysis and also to Jack
Merrin for designing and building microfabricated chambers for the project and for
the various discussions on making zebrafish extracts."
alternative_title:
- ISTA Thesis
article_processing_charge: No
author:
- first_name: Shayan
full_name: Shamipour, Shayan
id: 40B34FE2-F248-11E8-B48F-1D18A9856A87
last_name: Shamipour
citation:
ama: Shamipour S. Bulk actin dynamics drive phase segregation in zebrafish oocytes
. 2020. doi:10.15479/AT:ISTA:8350
apa: Shamipour, S. (2020). Bulk actin dynamics drive phase segregation in zebrafish
oocytes . Institute of Science and Technology Austria. https://doi.org/10.15479/AT:ISTA:8350
chicago: Shamipour, Shayan. “Bulk Actin Dynamics Drive Phase Segregation in Zebrafish
Oocytes .” Institute of Science and Technology Austria, 2020. https://doi.org/10.15479/AT:ISTA:8350.
ieee: S. Shamipour, “Bulk actin dynamics drive phase segregation in zebrafish oocytes
,” Institute of Science and Technology Austria, 2020.
ista: Shamipour S. 2020. Bulk actin dynamics drive phase segregation in zebrafish
oocytes . Institute of Science and Technology Austria.
mla: Shamipour, Shayan. Bulk Actin Dynamics Drive Phase Segregation in Zebrafish
Oocytes . Institute of Science and Technology Austria, 2020, doi:10.15479/AT:ISTA:8350.
short: S. Shamipour, Bulk Actin Dynamics Drive Phase Segregation in Zebrafish Oocytes
, Institute of Science and Technology Austria, 2020.
date_created: 2020-09-09T11:12:10Z
date_published: 2020-09-09T00:00:00Z
date_updated: 2023-09-27T14:16:45Z
day: '09'
ddc:
- '570'
degree_awarded: PhD
department:
- _id: BjHo
- _id: CaHe
doi: 10.15479/AT:ISTA:8350
file:
- access_level: closed
checksum: 6e47871c74f85008b9876112eb3fcfa1
content_type: application/vnd.openxmlformats-officedocument.wordprocessingml.document
creator: sshamip
date_created: 2020-09-09T11:06:27Z
date_updated: 2021-09-11T22:30:05Z
embargo_to: open_access
file_id: '8351'
file_name: Shayan-Thesis-Final.docx
file_size: 65194814
relation: source_file
- access_level: open_access
checksum: 1b44c57f04d7e8a6fe41b1c9c55a52a3
content_type: application/pdf
creator: sshamip
date_created: 2020-09-09T11:06:13Z
date_updated: 2021-09-11T22:30:05Z
embargo: 2021-09-10
file_id: '8352'
file_name: Shayan-Thesis-Final.pdf
file_size: 23729605
relation: main_file
file_date_updated: 2021-09-11T22:30:05Z
has_accepted_license: '1'
language:
- iso: eng
month: '09'
oa: 1
oa_version: None
page: '107'
publication_identifier:
issn:
- 2663-337X
publication_status: published
publisher: Institute of Science and Technology Austria
related_material:
record:
- id: '661'
relation: part_of_dissertation
status: public
- id: '6508'
relation: part_of_dissertation
status: public
- id: '7001'
relation: part_of_dissertation
status: public
- id: '735'
relation: part_of_dissertation
status: public
status: public
supervisor:
- first_name: Carl-Philipp J
full_name: Heisenberg, Carl-Philipp J
id: 39427864-F248-11E8-B48F-1D18A9856A87
last_name: Heisenberg
orcid: 0000-0002-0912-4566
- first_name: Björn
full_name: Hof, Björn
id: 3A374330-F248-11E8-B48F-1D18A9856A87
last_name: Hof
orcid: 0000-0003-2057-2754
title: 'Bulk actin dynamics drive phase segregation in zebrafish oocytes '
type: dissertation
user_id: c635000d-4b10-11ee-a964-aac5a93f6ac1
year: '2020'
...
---
_id: '5793'
abstract:
- lang: eng
text: The transcription coactivator, Yes-associated protein (YAP), which is a nuclear
effector of the Hippo signaling pathway, has been shown to be a mechano-transducer.
By using mutant fish and human 3D spheroids, we have recently demonstrated that
YAP is also a mechano-effector. YAP functions in three-dimensional (3D) morphogenesis
of organ and global body shape by controlling actomyosin-mediated tissue tension.
In this chapter, we present a platform that links the findings in fish embryos
with human cells. The protocols for analyzing tissue tension-mediated global body
shape/organ morphogenesis in vivo and ex vivo using medaka fish embryos and in
vitro using human cell spheroids represent useful tools for unraveling the molecular
mechanisms by which YAP functions in regulating global body/organ morphogenesis.
alternative_title:
- MIMB
author:
- first_name: Yoichi
full_name: Asaoka, Yoichi
last_name: Asaoka
- first_name: Hitoshi
full_name: Morita, Hitoshi
last_name: Morita
- first_name: Hiroko
full_name: Furumoto, Hiroko
last_name: Furumoto
- first_name: Carl-Philipp J
full_name: Heisenberg, Carl-Philipp J
id: 39427864-F248-11E8-B48F-1D18A9856A87
last_name: Heisenberg
orcid: 0000-0002-0912-4566
- first_name: Makoto
full_name: Furutani-Seiki, Makoto
last_name: Furutani-Seiki
citation:
ama: 'Asaoka Y, Morita H, Furumoto H, Heisenberg C-PJ, Furutani-Seiki M. Studying
YAP-mediated 3D morphogenesis using fish embryos and human spheroids. In: Hergovich
A, ed. The Hippo Pathway. Vol 1893. Methods in Molecular Biology. Springer;
2019:167-181. doi:10.1007/978-1-4939-8910-2_14'
apa: Asaoka, Y., Morita, H., Furumoto, H., Heisenberg, C.-P. J., & Furutani-Seiki,
M. (2019). Studying YAP-mediated 3D morphogenesis using fish embryos and human
spheroids. In A. Hergovich (Ed.), The hippo pathway (Vol. 1893, pp. 167–181).
Springer. https://doi.org/10.1007/978-1-4939-8910-2_14
chicago: Asaoka, Yoichi, Hitoshi Morita, Hiroko Furumoto, Carl-Philipp J Heisenberg,
and Makoto Furutani-Seiki. “Studying YAP-Mediated 3D Morphogenesis Using Fish
Embryos and Human Spheroids.” In The Hippo Pathway, edited by Alexander
Hergovich, 1893:167–81. Methods in Molecular Biology. Springer, 2019. https://doi.org/10.1007/978-1-4939-8910-2_14.
ieee: Y. Asaoka, H. Morita, H. Furumoto, C.-P. J. Heisenberg, and M. Furutani-Seiki,
“Studying YAP-mediated 3D morphogenesis using fish embryos and human spheroids,”
in The hippo pathway, vol. 1893, A. Hergovich, Ed. Springer, 2019, pp.
167–181.
ista: 'Asaoka Y, Morita H, Furumoto H, Heisenberg C-PJ, Furutani-Seiki M. 2019.Studying
YAP-mediated 3D morphogenesis using fish embryos and human spheroids. In: The
hippo pathway. MIMB, vol. 1893, 167–181.'
mla: Asaoka, Yoichi, et al. “Studying YAP-Mediated 3D Morphogenesis Using Fish Embryos
and Human Spheroids.” The Hippo Pathway, edited by Alexander Hergovich,
vol. 1893, Springer, 2019, pp. 167–81, doi:10.1007/978-1-4939-8910-2_14.
short: Y. Asaoka, H. Morita, H. Furumoto, C.-P.J. Heisenberg, M. Furutani-Seiki,
in:, A. Hergovich (Ed.), The Hippo Pathway, Springer, 2019, pp. 167–181.
date_created: 2019-01-06T22:59:11Z
date_published: 2019-01-01T00:00:00Z
date_updated: 2021-01-12T08:03:30Z
day: '01'
department:
- _id: CaHe
doi: 10.1007/978-1-4939-8910-2_14
editor:
- first_name: Alexander
full_name: Hergovich, Alexander
last_name: Hergovich
intvolume: ' 1893'
language:
- iso: eng
month: '01'
oa_version: None
page: 167-181
publication: The hippo pathway
publication_identifier:
isbn:
- 978-1-4939-8909-6
publication_status: published
publisher: Springer
quality_controlled: '1'
scopus_import: 1
series_title: Methods in Molecular Biology
status: public
title: Studying YAP-mediated 3D morphogenesis using fish embryos and human spheroids
type: book_chapter
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 1893
year: '2019'
...
---
_id: '6025'
abstract:
- lang: eng
text: Non-canonical Wnt signaling plays a central role for coordinated cell polarization
and directed migration in metazoan development. While spatiotemporally restricted
activation of non-canonical Wnt-signaling drives cell polarization in epithelial
tissues, it remains unclear whether such instructive activity is also critical
for directed mesenchymal cell migration. Here, we developed a light-activated
version of the non-canonical Wnt receptor Frizzled 7 (Fz7) to analyze how restricted
activation of non-canonical Wnt signaling affects directed anterior axial mesendoderm
(prechordal plate, ppl) cell migration within the zebrafish gastrula. We found
that Fz7 signaling is required for ppl cell protrusion formation and migration
and that spatiotemporally restricted ectopic activation is capable of redirecting
their migration. Finally, we show that uniform activation of Fz7 signaling in
ppl cells fully rescues defective directed cell migration in fz7 mutant embryos.
Together, our findings reveal that in contrast to the situation in epithelial
cells, non-canonical Wnt signaling functions permissively rather than instructively
in directed mesenchymal cell migration during gastrulation.
acknowledged_ssus:
- _id: Bio
- _id: LifeSc
article_number: e42093
article_processing_charge: No
author:
- first_name: Daniel
full_name: Capek, Daniel
id: 31C42484-F248-11E8-B48F-1D18A9856A87
last_name: Capek
orcid: 0000-0001-5199-9940
- first_name: Michael
full_name: Smutny, Michael
id: 3FE6E4E8-F248-11E8-B48F-1D18A9856A87
last_name: Smutny
orcid: 0000-0002-5920-9090
- first_name: Alexandra Madelaine
full_name: Tichy, Alexandra Madelaine
last_name: Tichy
- first_name: Maurizio
full_name: Morri, Maurizio
id: 4863116E-F248-11E8-B48F-1D18A9856A87
last_name: Morri
- first_name: Harald L
full_name: Janovjak, Harald L
id: 33BA6C30-F248-11E8-B48F-1D18A9856A87
last_name: Janovjak
orcid: 0000-0002-8023-9315
- first_name: Carl-Philipp J
full_name: Heisenberg, Carl-Philipp J
id: 39427864-F248-11E8-B48F-1D18A9856A87
last_name: Heisenberg
orcid: 0000-0002-0912-4566
citation:
ama: Capek D, Smutny M, Tichy AM, Morri M, Janovjak HL, Heisenberg C-PJ. Light-activated
Frizzled7 reveals a permissive role of non-canonical wnt signaling in mesendoderm
cell migration. eLife. 2019;8. doi:10.7554/eLife.42093
apa: Capek, D., Smutny, M., Tichy, A. M., Morri, M., Janovjak, H. L., & Heisenberg,
C.-P. J. (2019). Light-activated Frizzled7 reveals a permissive role of non-canonical
wnt signaling in mesendoderm cell migration. ELife. eLife Sciences Publications.
https://doi.org/10.7554/eLife.42093
chicago: Capek, Daniel, Michael Smutny, Alexandra Madelaine Tichy, Maurizio Morri,
Harald L Janovjak, and Carl-Philipp J Heisenberg. “Light-Activated Frizzled7 Reveals
a Permissive Role of Non-Canonical Wnt Signaling in Mesendoderm Cell Migration.”
ELife. eLife Sciences Publications, 2019. https://doi.org/10.7554/eLife.42093.
ieee: D. Capek, M. Smutny, A. M. Tichy, M. Morri, H. L. Janovjak, and C.-P. J. Heisenberg,
“Light-activated Frizzled7 reveals a permissive role of non-canonical wnt signaling
in mesendoderm cell migration,” eLife, vol. 8. eLife Sciences Publications,
2019.
ista: Capek D, Smutny M, Tichy AM, Morri M, Janovjak HL, Heisenberg C-PJ. 2019.
Light-activated Frizzled7 reveals a permissive role of non-canonical wnt signaling
in mesendoderm cell migration. eLife. 8, e42093.
mla: Capek, Daniel, et al. “Light-Activated Frizzled7 Reveals a Permissive Role
of Non-Canonical Wnt Signaling in Mesendoderm Cell Migration.” ELife, vol.
8, e42093, eLife Sciences Publications, 2019, doi:10.7554/eLife.42093.
short: D. Capek, M. Smutny, A.M. Tichy, M. Morri, H.L. Janovjak, C.-P.J. Heisenberg,
ELife 8 (2019).
date_created: 2019-02-17T22:59:22Z
date_published: 2019-02-06T00:00:00Z
date_updated: 2023-08-24T14:46:01Z
day: '06'
ddc:
- '570'
department:
- _id: CaHe
- _id: HaJa
doi: 10.7554/eLife.42093
ec_funded: 1
external_id:
isi:
- '000458025300001'
file:
- access_level: open_access
checksum: 6cb4ca6d4aa96f6f187a5983aa3e660a
content_type: application/pdf
creator: dernst
date_created: 2019-02-18T15:17:21Z
date_updated: 2020-07-14T12:47:17Z
file_id: '6041'
file_name: 2019_elife_Capek.pdf
file_size: 5500707
relation: main_file
file_date_updated: 2020-07-14T12:47:17Z
has_accepted_license: '1'
intvolume: ' 8'
isi: 1
language:
- iso: eng
month: '02'
oa: 1
oa_version: Published Version
project:
- _id: 260F1432-B435-11E9-9278-68D0E5697425
call_identifier: H2020
grant_number: '742573'
name: Interaction and feedback between cell mechanics and fate specification in
vertebrate gastrulation
publication: eLife
publication_status: published
publisher: eLife Sciences Publications
quality_controlled: '1'
scopus_import: '1'
status: public
title: Light-activated Frizzled7 reveals a permissive role of non-canonical wnt signaling
in mesendoderm cell migration
tmp:
image: /images/cc_by.png
legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
short: CC BY (4.0)
type: journal_article
user_id: 4359f0d1-fa6c-11eb-b949-802e58b17ae8
volume: 8
year: '2019'
...
---
_id: '6087'
abstract:
- lang: eng
text: Cell fate specification by lateral inhibition typically involves contact signaling
through the Delta-Notch signaling pathway. However, whether this is the only signaling
mode mediating lateral inhibition remains unclear. Here we show that in zebrafish
oogenesis, a group of cells within the granulosa cell layer at the oocyte animal
pole acquire elevated levels of the transcriptional coactivator TAZ in their nuclei.
One of these cells, the future micropyle precursor cell (MPC), accumulates increasingly
high levels of nuclear TAZ and grows faster than its surrounding cells, mechanically
compressing those cells, which ultimately lose TAZ from their nuclei. Strikingly,
relieving neighbor-cell compression by MPC ablation or aspiration restores nuclear
TAZ accumulation in neighboring cells, eventually leading to MPC re-specification
from these cells. Conversely, MPC specification is defective in taz−/− follicles.
These findings uncover a novel mode of lateral inhibition in cell fate specification
based on mechanical signals controlling TAZ activity.
acknowledged_ssus:
- _id: Bio
- _id: EM-Fac
- _id: LifeSc
acknowledgement: We thank Roland Dosch, Makoto Furutani-Seiki, Brian Link, Mary Mullins,
and Masazumi Tada for providing transgenic and/or mutant zebrafish lines; Alexandra
Schauer, Shayan Shami-Pour, and the rest of the Heisenberg lab for technical assistance
and feedback on the manuscript; and the Bioimaging, Electron Microscopy, and Zebrafish
facilities of IST Austria for continuous support. This work was supported by an
ERC advanced grant ( MECSPEC to C.-P.H.).
article_processing_charge: No
article_type: original
author:
- first_name: Peng
full_name: Xia, Peng
id: 4AB6C7D0-F248-11E8-B48F-1D18A9856A87
last_name: Xia
orcid: 0000-0002-5419-7756
- first_name: Daniel J
full_name: Gütl, Daniel J
id: 381929CE-F248-11E8-B48F-1D18A9856A87
last_name: Gütl
- first_name: Vanessa
full_name: Zheden, Vanessa
id: 39C5A68A-F248-11E8-B48F-1D18A9856A87
last_name: Zheden
orcid: 0000-0002-9438-4783
- first_name: Carl-Philipp J
full_name: Heisenberg, Carl-Philipp J
id: 39427864-F248-11E8-B48F-1D18A9856A87
last_name: Heisenberg
orcid: 0000-0002-0912-4566
citation:
ama: Xia P, Gütl DJ, Zheden V, Heisenberg C-PJ. Lateral inhibition in cell specification
mediated by mechanical signals modulating TAZ activity. Cell. 2019;176(6):1379-1392.e14.
doi:10.1016/j.cell.2019.01.019
apa: Xia, P., Gütl, D. J., Zheden, V., & Heisenberg, C.-P. J. (2019). Lateral
inhibition in cell specification mediated by mechanical signals modulating TAZ
activity. Cell. Elsevier. https://doi.org/10.1016/j.cell.2019.01.019
chicago: Xia, Peng, Daniel J Gütl, Vanessa Zheden, and Carl-Philipp J Heisenberg.
“Lateral Inhibition in Cell Specification Mediated by Mechanical Signals Modulating
TAZ Activity.” Cell. Elsevier, 2019. https://doi.org/10.1016/j.cell.2019.01.019.
ieee: P. Xia, D. J. Gütl, V. Zheden, and C.-P. J. Heisenberg, “Lateral inhibition
in cell specification mediated by mechanical signals modulating TAZ activity,”
Cell, vol. 176, no. 6. Elsevier, p. 1379–1392.e14, 2019.
ista: Xia P, Gütl DJ, Zheden V, Heisenberg C-PJ. 2019. Lateral inhibition in cell
specification mediated by mechanical signals modulating TAZ activity. Cell. 176(6),
1379–1392.e14.
mla: Xia, Peng, et al. “Lateral Inhibition in Cell Specification Mediated by Mechanical
Signals Modulating TAZ Activity.” Cell, vol. 176, no. 6, Elsevier, 2019,
p. 1379–1392.e14, doi:10.1016/j.cell.2019.01.019.
short: P. Xia, D.J. Gütl, V. Zheden, C.-P.J. Heisenberg, Cell 176 (2019) 1379–1392.e14.
date_created: 2019-03-10T22:59:19Z
date_published: 2019-03-07T00:00:00Z
date_updated: 2023-08-25T08:02:23Z
day: '07'
department:
- _id: CaHe
- _id: EM-Fac
doi: 10.1016/j.cell.2019.01.019
ec_funded: 1
external_id:
isi:
- '000460509600013'
pmid:
- '30773315'
intvolume: ' 176'
isi: 1
issue: '6'
language:
- iso: eng
main_file_link:
- open_access: '1'
url: https://doi.org/10.1016/j.cell.2019.01.019
month: '03'
oa: 1
oa_version: Published Version
page: 1379-1392.e14
pmid: 1
project:
- _id: 260F1432-B435-11E9-9278-68D0E5697425
call_identifier: H2020
grant_number: '742573'
name: Interaction and feedback between cell mechanics and fate specification in
vertebrate gastrulation
publication: Cell
publication_status: published
publisher: Elsevier
quality_controlled: '1'
related_material:
link:
- description: News on IST Homepage
relation: press_release
url: https://ist.ac.at/en/news/in-zebrafish-eggs-most-rapidly-growing-cell-inhibits-its-neighbours-through-mechanical-signals/
scopus_import: '1'
status: public
title: Lateral inhibition in cell specification mediated by mechanical signals modulating
TAZ activity
type: journal_article
user_id: 4359f0d1-fa6c-11eb-b949-802e58b17ae8
volume: 176
year: '2019'
...
---
_id: '6601'
abstract:
- lang: eng
text: There is increasing evidence that both mechanical and biochemical signals
play important roles in development and disease. The development of complex organisms,
in particular, has been proposed to rely on the feedback between mechanical and
biochemical patterning events. This feedback occurs at the molecular level via
mechanosensation but can also arise as an emergent property of the system at the
cellular and tissue level. In recent years, dynamic changes in tissue geometry,
flow, rheology, and cell fate specification have emerged as key platforms of mechanochemical
feedback loops in multiple processes. Here, we review recent experimental and
theoretical advances in understanding how these feedbacks function in development
and disease.
article_processing_charge: No
article_type: review
author:
- first_name: Edouard B
full_name: Hannezo, Edouard B
id: 3A9DB764-F248-11E8-B48F-1D18A9856A87
last_name: Hannezo
orcid: 0000-0001-6005-1561
- first_name: Carl-Philipp J
full_name: Heisenberg, Carl-Philipp J
id: 39427864-F248-11E8-B48F-1D18A9856A87
last_name: Heisenberg
orcid: 0000-0002-0912-4566
citation:
ama: Hannezo EB, Heisenberg C-PJ. Mechanochemical feedback loops in development
and disease. Cell. 2019;178(1):12-25. doi:10.1016/j.cell.2019.05.052
apa: Hannezo, E. B., & Heisenberg, C.-P. J. (2019). Mechanochemical feedback
loops in development and disease. Cell. Elsevier. https://doi.org/10.1016/j.cell.2019.05.052
chicago: Hannezo, Edouard B, and Carl-Philipp J Heisenberg. “Mechanochemical Feedback
Loops in Development and Disease.” Cell. Elsevier, 2019. https://doi.org/10.1016/j.cell.2019.05.052.
ieee: E. B. Hannezo and C.-P. J. Heisenberg, “Mechanochemical feedback loops in
development and disease,” Cell, vol. 178, no. 1. Elsevier, pp. 12–25, 2019.
ista: Hannezo EB, Heisenberg C-PJ. 2019. Mechanochemical feedback loops in development
and disease. Cell. 178(1), 12–25.
mla: Hannezo, Edouard B., and Carl-Philipp J. Heisenberg. “Mechanochemical Feedback
Loops in Development and Disease.” Cell, vol. 178, no. 1, Elsevier, 2019,
pp. 12–25, doi:10.1016/j.cell.2019.05.052.
short: E.B. Hannezo, C.-P.J. Heisenberg, Cell 178 (2019) 12–25.
date_created: 2019-06-30T21:59:11Z
date_published: 2019-07-27T00:00:00Z
date_updated: 2023-08-28T12:25:21Z
day: '27'
department:
- _id: CaHe
- _id: EdHa
doi: 10.1016/j.cell.2019.05.052
ec_funded: 1
external_id:
isi:
- '000473002700005'
pmid:
- '31251912'
intvolume: ' 178'
isi: 1
issue: '1'
language:
- iso: eng
main_file_link:
- open_access: '1'
url: https://doi.org/10.1016/j.cell.2019.05.052
month: '07'
oa: 1
oa_version: Published Version
page: 12-25
pmid: 1
project:
- _id: 260F1432-B435-11E9-9278-68D0E5697425
call_identifier: H2020
grant_number: '742573'
name: Interaction and feedback between cell mechanics and fate specification in
vertebrate gastrulation
- _id: 268294B6-B435-11E9-9278-68D0E5697425
call_identifier: FWF
grant_number: P31639
name: Active mechano-chemical description of the cell cytoskeleton
publication: Cell
publication_identifier:
issn:
- '00928674'
publication_status: published
publisher: Elsevier
quality_controlled: '1'
scopus_import: '1'
status: public
title: Mechanochemical feedback loops in development and disease
type: journal_article
user_id: 4359f0d1-fa6c-11eb-b949-802e58b17ae8
volume: 178
year: '2019'
...
---
_id: '6631'
abstract:
- lang: eng
text: The spatiotemporal organization of cell divisions constitutes an integral
part in the development of multicellular organisms, and mis-regulation of cell
divisions can lead to severe developmental defects. Cell divisions have an important
morphogenetic function in development by regulating growth and shape acquisition
of developing tissues, and, conversely, tissue morphogenesis is known to affect
both the rate and orientation of cell divisions. Moreover, cell divisions are
associated with an extensive reorganization of the cytoskeleton and adhesion apparatus
in the dividing cells that in turn can affect large-scale tissue rheological properties.
Thus, the interplay between cell divisions and tissue morphogenesis plays a key
role in embryo and tissue morphogenesis.
article_processing_charge: No
author:
- first_name: Benoit G
full_name: Godard, Benoit G
id: 33280250-F248-11E8-B48F-1D18A9856A87
last_name: Godard
- first_name: Carl-Philipp J
full_name: Heisenberg, Carl-Philipp J
id: 39427864-F248-11E8-B48F-1D18A9856A87
last_name: Heisenberg
orcid: 0000-0002-0912-4566
citation:
ama: Godard BG, Heisenberg C-PJ. Cell division and tissue mechanics. Current
Opinion in Cell Biology. 2019;60:114-120. doi:10.1016/j.ceb.2019.05.007
apa: Godard, B. G., & Heisenberg, C.-P. J. (2019). Cell division and tissue
mechanics. Current Opinion in Cell Biology. Elsevier. https://doi.org/10.1016/j.ceb.2019.05.007
chicago: Godard, Benoit G, and Carl-Philipp J Heisenberg. “Cell Division and Tissue
Mechanics.” Current Opinion in Cell Biology. Elsevier, 2019. https://doi.org/10.1016/j.ceb.2019.05.007.
ieee: B. G. Godard and C.-P. J. Heisenberg, “Cell division and tissue mechanics,”
Current Opinion in Cell Biology, vol. 60. Elsevier, pp. 114–120, 2019.
ista: Godard BG, Heisenberg C-PJ. 2019. Cell division and tissue mechanics. Current
Opinion in Cell Biology. 60, 114–120.
mla: Godard, Benoit G., and Carl-Philipp J. Heisenberg. “Cell Division and Tissue
Mechanics.” Current Opinion in Cell Biology, vol. 60, Elsevier, 2019, pp.
114–20, doi:10.1016/j.ceb.2019.05.007.
short: B.G. Godard, C.-P.J. Heisenberg, Current Opinion in Cell Biology 60 (2019)
114–120.
date_created: 2019-07-14T21:59:17Z
date_published: 2019-10-01T00:00:00Z
date_updated: 2023-08-29T06:33:14Z
day: '01'
department:
- _id: CaHe
doi: 10.1016/j.ceb.2019.05.007
external_id:
isi:
- '000486545800016'
intvolume: ' 60'
isi: 1
language:
- iso: eng
month: '10'
oa_version: None
page: 114-120
publication: Current Opinion in Cell Biology
publication_identifier:
issn:
- 0955-0674
publication_status: published
publisher: Elsevier
quality_controlled: '1'
scopus_import: '1'
status: public
title: Cell division and tissue mechanics
type: journal_article
user_id: 4359f0d1-fa6c-11eb-b949-802e58b17ae8
volume: 60
year: '2019'
...
---
_id: '6837'
abstract:
- lang: eng
text: Migrasomes are a recently discovered type of extracellular vesicles that are
characteristically generated along retraction fibers in migrating cells. Two studies
now show how migrasomes are formed and how they function in the physiologically
relevant context of the developing zebrafish embryo.
article_processing_charge: No
author:
- first_name: Ste
full_name: Tavano, Ste
id: 2F162F0C-F248-11E8-B48F-1D18A9856A87
last_name: Tavano
orcid: 0000-0001-9970-7804
- first_name: Carl-Philipp J
full_name: Heisenberg, Carl-Philipp J
id: 39427864-F248-11E8-B48F-1D18A9856A87
last_name: Heisenberg
orcid: 0000-0002-0912-4566
citation:
ama: Tavano S, Heisenberg C-PJ. Migrasomes take center stage. Nature Cell Biology.
2019;21(8):918-920. doi:10.1038/s41556-019-0369-3
apa: Tavano, S., & Heisenberg, C.-P. J. (2019). Migrasomes take center stage.
Nature Cell Biology. Springer Nature. https://doi.org/10.1038/s41556-019-0369-3
chicago: Tavano, Ste, and Carl-Philipp J Heisenberg. “Migrasomes Take Center Stage.”
Nature Cell Biology. Springer Nature, 2019. https://doi.org/10.1038/s41556-019-0369-3.
ieee: S. Tavano and C.-P. J. Heisenberg, “Migrasomes take center stage,” Nature
Cell Biology, vol. 21, no. 8. Springer Nature, pp. 918–920, 2019.
ista: Tavano S, Heisenberg C-PJ. 2019. Migrasomes take center stage. Nature Cell
Biology. 21(8), 918–920.
mla: Tavano, Ste, and Carl-Philipp J. Heisenberg. “Migrasomes Take Center Stage.”
Nature Cell Biology, vol. 21, no. 8, Springer Nature, 2019, pp. 918–20,
doi:10.1038/s41556-019-0369-3.
short: S. Tavano, C.-P.J. Heisenberg, Nature Cell Biology 21 (2019) 918–920.
date_created: 2019-09-01T22:00:57Z
date_published: 2019-08-01T00:00:00Z
date_updated: 2023-08-29T07:42:20Z
day: '01'
department:
- _id: CaHe
doi: 10.1038/s41556-019-0369-3
external_id:
isi:
- '000478029000003'
pmid:
- '31371826'
intvolume: ' 21'
isi: 1
issue: '8'
language:
- iso: eng
month: '08'
oa_version: None
page: 918-920
pmid: 1
publication: Nature Cell Biology
publication_identifier:
eissn:
- 1476-4679
publication_status: published
publisher: Springer Nature
quality_controlled: '1'
scopus_import: '1'
status: public
title: Migrasomes take center stage
type: journal_article
user_id: 4359f0d1-fa6c-11eb-b949-802e58b17ae8
volume: 21
year: '2019'
...
---
_id: '6899'
abstract:
- lang: eng
text: Intra-organ communication guides morphogenetic processes that are essential
for an organ to carry out complex physiological functions. In the heart, the growth
of the myocardium is tightly coupled to that of the endocardium, a specialized
endothelial tissue that lines its interior. Several molecular pathways have been
implicated in the communication between these tissues including secreted factors,
components of the extracellular matrix, or proteins involved in cell-cell communication.
Yet, it is unknown how the growth of the endocardium is coordinated with that
of the myocardium. Here, we show that an increased expansion of the myocardial
atrial chamber volume generates higher junctional forces within endocardial cells.
This leads to biomechanical signaling involving VE-cadherin, triggering nuclear
localization of the Hippo pathway transcriptional regulator Yap1 and endocardial
proliferation. Our work suggests that the growth of the endocardium results from
myocardial chamber volume expansion and ends when the tension on the tissue is
relaxed.
article_processing_charge: No
author:
- first_name: Dorothee
full_name: Bornhorst, Dorothee
last_name: Bornhorst
- first_name: Peng
full_name: Xia, Peng
id: 4AB6C7D0-F248-11E8-B48F-1D18A9856A87
last_name: Xia
orcid: 0000-0002-5419-7756
- first_name: Hiroyuki
full_name: Nakajima, Hiroyuki
last_name: Nakajima
- first_name: Chaitanya
full_name: Dingare, Chaitanya
last_name: Dingare
- first_name: Wiebke
full_name: Herzog, Wiebke
last_name: Herzog
- first_name: Virginie
full_name: Lecaudey, Virginie
last_name: Lecaudey
- first_name: Naoki
full_name: Mochizuki, Naoki
last_name: Mochizuki
- first_name: Carl-Philipp J
full_name: Heisenberg, Carl-Philipp J
id: 39427864-F248-11E8-B48F-1D18A9856A87
last_name: Heisenberg
orcid: 0000-0002-0912-4566
- first_name: Deborah
full_name: Yelon, Deborah
last_name: Yelon
- first_name: Salim
full_name: Abdelilah-Seyfried, Salim
last_name: Abdelilah-Seyfried
citation:
ama: Bornhorst D, Xia P, Nakajima H, et al. Biomechanical signaling within the developing
zebrafish heart attunes endocardial growth to myocardial chamber dimensions. Nature
communications. 2019;10(1):4113. doi:10.1038/s41467-019-12068-x
apa: Bornhorst, D., Xia, P., Nakajima, H., Dingare, C., Herzog, W., Lecaudey, V.,
… Abdelilah-Seyfried, S. (2019). Biomechanical signaling within the developing
zebrafish heart attunes endocardial growth to myocardial chamber dimensions. Nature
Communications. Nature Publishing Group. https://doi.org/10.1038/s41467-019-12068-x
chicago: Bornhorst, Dorothee, Peng Xia, Hiroyuki Nakajima, Chaitanya Dingare, Wiebke
Herzog, Virginie Lecaudey, Naoki Mochizuki, Carl-Philipp J Heisenberg, Deborah
Yelon, and Salim Abdelilah-Seyfried. “Biomechanical Signaling within the Developing
Zebrafish Heart Attunes Endocardial Growth to Myocardial Chamber Dimensions.”
Nature Communications. Nature Publishing Group, 2019. https://doi.org/10.1038/s41467-019-12068-x.
ieee: D. Bornhorst et al., “Biomechanical signaling within the developing
zebrafish heart attunes endocardial growth to myocardial chamber dimensions,”
Nature communications, vol. 10, no. 1. Nature Publishing Group, p. 4113,
2019.
ista: Bornhorst D, Xia P, Nakajima H, Dingare C, Herzog W, Lecaudey V, Mochizuki
N, Heisenberg C-PJ, Yelon D, Abdelilah-Seyfried S. 2019. Biomechanical signaling
within the developing zebrafish heart attunes endocardial growth to myocardial
chamber dimensions. Nature communications. 10(1), 4113.
mla: Bornhorst, Dorothee, et al. “Biomechanical Signaling within the Developing
Zebrafish Heart Attunes Endocardial Growth to Myocardial Chamber Dimensions.”
Nature Communications, vol. 10, no. 1, Nature Publishing Group, 2019, p.
4113, doi:10.1038/s41467-019-12068-x.
short: D. Bornhorst, P. Xia, H. Nakajima, C. Dingare, W. Herzog, V. Lecaudey, N.
Mochizuki, C.-P.J. Heisenberg, D. Yelon, S. Abdelilah-Seyfried, Nature Communications
10 (2019) 4113.
date_created: 2019-09-22T22:00:37Z
date_published: 2019-09-11T00:00:00Z
date_updated: 2023-08-30T06:21:23Z
day: '11'
ddc:
- '570'
department:
- _id: CaHe
doi: 10.1038/s41467-019-12068-x
external_id:
isi:
- '000485216800009'
pmid:
- '31511517'
file:
- access_level: open_access
checksum: 62c2512712e16d27c1797d318d14ba9f
content_type: application/pdf
creator: kschuh
date_created: 2019-10-01T11:18:50Z
date_updated: 2020-07-14T12:47:44Z
file_id: '6926'
file_name: 2019_Nature_Bornhorst.pdf
file_size: 3905793
relation: main_file
file_date_updated: 2020-07-14T12:47:44Z
has_accepted_license: '1'
intvolume: ' 10'
isi: 1
issue: '1'
language:
- iso: eng
month: '09'
oa: 1
oa_version: Published Version
page: '4113'
pmid: 1
publication: Nature communications
publication_identifier:
eissn:
- '20411723'
publication_status: published
publisher: Nature Publishing Group
quality_controlled: '1'
scopus_import: '1'
status: public
title: Biomechanical signaling within the developing zebrafish heart attunes endocardial
growth to myocardial chamber dimensions
tmp:
image: /images/cc_by.png
legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
short: CC BY (4.0)
type: journal_article
user_id: 4359f0d1-fa6c-11eb-b949-802e58b17ae8
volume: 10
year: '2019'
...
---
_id: '6980'
abstract:
- lang: eng
text: Tissue morphogenesis in multicellular organisms is brought about by spatiotemporal
coordination of mechanical and chemical signals. Extensive work on how mechanical
forces together with the well‐established morphogen signalling pathways can actively
shape living tissues has revealed evolutionary conserved mechanochemical features
of embryonic development. More recently, attention has been drawn to the description
of tissue material properties and how they can influence certain morphogenetic
processes. Interestingly, besides the role of tissue material properties in determining
how much tissues deform in response to force application, there is increasing
theoretical and experimental evidence, suggesting that tissue material properties
can abruptly and drastically change in development. These changes resemble phase
transitions, pointing at the intriguing possibility that important morphogenetic
processes in development, such as symmetry breaking and self‐organization, might
be mediated by tissue phase transitions. In this review, we summarize recent findings
on the regulation and role of tissue material properties in the context of the
developing embryo. We posit that abrupt changes of tissue rheological properties
may have important implications in maintaining the balance between robustness
and adaptability during embryonic development.
article_number: e102497
article_processing_charge: Yes (via OA deal)
article_type: review
author:
- first_name: Nicoletta
full_name: Petridou, Nicoletta
id: 2A003F6C-F248-11E8-B48F-1D18A9856A87
last_name: Petridou
orcid: 0000-0002-8451-1195
- first_name: Carl-Philipp J
full_name: Heisenberg, Carl-Philipp J
id: 39427864-F248-11E8-B48F-1D18A9856A87
last_name: Heisenberg
orcid: 0000-0002-0912-4566
citation:
ama: Petridou N, Heisenberg C-PJ. Tissue rheology in embryonic organization. The
EMBO Journal. 2019;38(20). doi:10.15252/embj.2019102497
apa: Petridou, N., & Heisenberg, C.-P. J. (2019). Tissue rheology in embryonic
organization. The EMBO Journal. EMBO. https://doi.org/10.15252/embj.2019102497
chicago: Petridou, Nicoletta, and Carl-Philipp J Heisenberg. “Tissue Rheology in
Embryonic Organization.” The EMBO Journal. EMBO, 2019. https://doi.org/10.15252/embj.2019102497.
ieee: N. Petridou and C.-P. J. Heisenberg, “Tissue rheology in embryonic organization,”
The EMBO Journal, vol. 38, no. 20. EMBO, 2019.
ista: Petridou N, Heisenberg C-PJ. 2019. Tissue rheology in embryonic organization.
The EMBO Journal. 38(20), e102497.
mla: Petridou, Nicoletta, and Carl-Philipp J. Heisenberg. “Tissue Rheology in Embryonic
Organization.” The EMBO Journal, vol. 38, no. 20, e102497, EMBO, 2019,
doi:10.15252/embj.2019102497.
short: N. Petridou, C.-P.J. Heisenberg, The EMBO Journal 38 (2019).
date_created: 2019-11-04T15:24:29Z
date_published: 2019-10-15T00:00:00Z
date_updated: 2023-09-05T13:04:13Z
day: '15'
ddc:
- '570'
department:
- _id: CaHe
doi: 10.15252/embj.2019102497
ec_funded: 1
external_id:
isi:
- '000485561900001'
pmid:
- '31512749'
file:
- access_level: open_access
checksum: 76f7f4e79ab6d850c30017a69726fd85
content_type: application/pdf
creator: dernst
date_created: 2019-11-04T15:30:08Z
date_updated: 2020-07-14T12:47:46Z
file_id: '6981'
file_name: 2019_Embo_Petridou.pdf
file_size: 847356
relation: main_file
file_date_updated: 2020-07-14T12:47:46Z
has_accepted_license: '1'
intvolume: ' 38'
isi: 1
issue: '20'
language:
- iso: eng
month: '10'
oa: 1
oa_version: Published Version
pmid: 1
project:
- _id: 260F1432-B435-11E9-9278-68D0E5697425
call_identifier: H2020
grant_number: '742573'
name: Interaction and feedback between cell mechanics and fate specification in
vertebrate gastrulation
- _id: 2693FD8C-B435-11E9-9278-68D0E5697425
call_identifier: FWF
grant_number: V00736
name: Tissue material properties in embryonic development
publication: The EMBO Journal
publication_identifier:
eissn:
- 1460-2075
issn:
- 0261-4189
publication_status: published
publisher: EMBO
quality_controlled: '1'
scopus_import: '1'
status: public
title: Tissue rheology in embryonic organization
tmp:
image: /images/cc_by.png
legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
short: CC BY (4.0)
type: journal_article
user_id: c635000d-4b10-11ee-a964-aac5a93f6ac1
volume: 38
year: '2019'
...
---
_id: '6987'
abstract:
- lang: eng
text: Cells are arranged into species-specific patterns during early embryogenesis.
Such cell division patterns are important since they often reflect the distribution
of localized cortical factors from eggs/fertilized eggs to specific cells as well
as the emergence of organismal form. However, it has proven difficult to reveal
the mechanisms that underlie the emergence of cell positioning patterns that underlie
embryonic shape, likely because a systems-level approach is required that integrates
cell biological, genetic, developmental, and mechanical parameters. The choice
of organism to address such questions is also important. Because ascidians display
the most extreme form of invariant cleavage pattern among the metazoans, we have
been analyzing the cell biological mechanisms that underpin three aspects of cell
division (unequal cell division (UCD), oriented cell division (OCD), and asynchronous
cell cycles) which affect the overall shape of the blastula-stage ascidian embryo
composed of 64 cells. In ascidians, UCD creates two small cells at the 16-cell
stage that in turn undergo two further successive rounds of UCD. Starting at the
16-cell stage, the cell cycle becomes asynchronous, whereby the vegetal half divides
before the animal half, thus creating 24-, 32-, 44-, and then 64-cell stages.
Perturbing either UCD or the alternate cell division rhythm perturbs cell position.
We propose that dynamic cell shape changes propagate throughout the embryo via
cell-cell contacts to create the ascidian-specific invariant cleavage pattern.
alternative_title:
- RESULTS
article_processing_charge: No
author:
- first_name: Alex
full_name: McDougall, Alex
last_name: McDougall
- first_name: Janet
full_name: Chenevert, Janet
last_name: Chenevert
- first_name: Benoit G
full_name: Godard, Benoit G
id: 33280250-F248-11E8-B48F-1D18A9856A87
last_name: Godard
- first_name: Remi
full_name: Dumollard, Remi
last_name: Dumollard
citation:
ama: 'McDougall A, Chenevert J, Godard BG, Dumollard R. Emergence of embryo shape
during cleavage divisions. In: Tworzydlo W, Bilinski SM, eds. Evo-Devo: Non-Model
Species in Cell and Developmental Biology. Vol 68. Springer Nature; 2019:127-154.
doi:10.1007/978-3-030-23459-1_6'
apa: 'McDougall, A., Chenevert, J., Godard, B. G., & Dumollard, R. (2019). Emergence
of embryo shape during cleavage divisions. In W. Tworzydlo & S. M. Bilinski
(Eds.), Evo-Devo: Non-model species in cell and developmental biology (Vol.
68, pp. 127–154). Springer Nature. https://doi.org/10.1007/978-3-030-23459-1_6'
chicago: 'McDougall, Alex, Janet Chenevert, Benoit G Godard, and Remi Dumollard.
“Emergence of Embryo Shape during Cleavage Divisions.” In Evo-Devo: Non-Model
Species in Cell and Developmental Biology, edited by Waclaw Tworzydlo and
Szczepan M. Bilinski, 68:127–54. Springer Nature, 2019. https://doi.org/10.1007/978-3-030-23459-1_6.'
ieee: 'A. McDougall, J. Chenevert, B. G. Godard, and R. Dumollard, “Emergence of
embryo shape during cleavage divisions,” in Evo-Devo: Non-model species in
cell and developmental biology, vol. 68, W. Tworzydlo and S. M. Bilinski,
Eds. Springer Nature, 2019, pp. 127–154.'
ista: 'McDougall A, Chenevert J, Godard BG, Dumollard R. 2019.Emergence of embryo
shape during cleavage divisions. In: Evo-Devo: Non-model species in cell and developmental
biology. RESULTS, vol. 68, 127–154.'
mla: 'McDougall, Alex, et al. “Emergence of Embryo Shape during Cleavage Divisions.”
Evo-Devo: Non-Model Species in Cell and Developmental Biology, edited by
Waclaw Tworzydlo and Szczepan M. Bilinski, vol. 68, Springer Nature, 2019, pp.
127–54, doi:10.1007/978-3-030-23459-1_6.'
short: 'A. McDougall, J. Chenevert, B.G. Godard, R. Dumollard, in:, W. Tworzydlo,
S.M. Bilinski (Eds.), Evo-Devo: Non-Model Species in Cell and Developmental Biology,
Springer Nature, 2019, pp. 127–154.'
date_created: 2019-11-04T16:20:19Z
date_published: 2019-10-10T00:00:00Z
date_updated: 2023-09-05T15:01:12Z
day: '10'
ddc:
- '570'
department:
- _id: CaHe
doi: 10.1007/978-3-030-23459-1_6
editor:
- first_name: Waclaw
full_name: Tworzydlo, Waclaw
last_name: Tworzydlo
- first_name: Szczepan M.
full_name: Bilinski, Szczepan M.
last_name: Bilinski
external_id:
pmid:
- '31598855'
file:
- access_level: open_access
checksum: 7f43e1e3706d15061475c5c57efc2786
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language:
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month: '10'
oa: 1
oa_version: Submitted Version
page: 127-154
pmid: 1
publication: 'Evo-Devo: Non-model species in cell and developmental biology'
publication_identifier:
eissn:
- 1861-0412
isbn:
- '9783030234584'
- '9783030234591'
issn:
- 0080-1844
publication_status: published
publisher: Springer Nature
quality_controlled: '1'
scopus_import: '1'
status: public
title: Emergence of embryo shape during cleavage divisions
type: book_chapter
user_id: c635000d-4b10-11ee-a964-aac5a93f6ac1
volume: 68
year: '2019'
...
---
_id: '7186'
abstract:
- lang: eng
text: "Tissue morphogenesis in developmental or physiological processes is regulated
by molecular\r\nand mechanical signals. While the molecular signaling cascades
are increasingly well\r\ndescribed, the mechanical signals affecting tissue shape
changes have only recently been\r\nstudied in greater detail. To gain more insight
into the mechanochemical and biophysical\r\nbasis of an epithelial spreading process
(epiboly) in early zebrafish development, we studied\r\ncell-cell junction formation
and actomyosin network dynamics at the boundary between\r\nsurface layer epithelial
cells (EVL) and the yolk syncytial layer (YSL). During zebrafish epiboly,\r\nthe
cell mass sitting on top of the yolk cell spreads to engulf the yolk cell by the
end of\r\ngastrulation. It has been previously shown that an actomyosin ring residing
within the YSL\r\npulls on the EVL tissue through a cable-constriction and a flow-friction
motor, thereby\r\ndragging the tissue vegetal wards. Pulling forces are likely
transmitted from the YSL\r\nactomyosin ring to EVL cells; however, the nature
and formation of the junctional structure\r\nmediating this process has not been
well described so far. Therefore, our main aim was to\r\ndetermine the nature,
dynamics and potential function of the EVL-YSL junction during this\r\nepithelial
tissue spreading. Specifically, we show that the EVL-YSL junction is a\r\nmechanosensitive
structure, predominantly made of tight junction (TJ) proteins. The process\r\nof
TJ mechanosensation depends on the retrograde flow of non-junctional, phase-separated\r\nZonula
Occludens-1 (ZO-1) protein clusters towards the EVL-YSL boundary. Interestingly,
we\r\ncould demonstrate that ZO-1 is present in a non-junctional pool on the surface
of the yolk\r\ncell, and ZO-1 undergoes a phase separation process that likely
renders the protein\r\nresponsive to flows. These flows are directed towards the
junction and mediate proper\r\ntension-dependent recruitment of ZO-1. Upon reaching
the EVL-YSL junction ZO-1 gets\r\nincorporated into the junctional pool mediated
through its direct actin-binding domain.\r\nWhen the non-junctional pool and/or
ZO-1 direct actin binding is absent, TJs fail in their\r\nproper mechanosensitive
responses resulting in slower tissue spreading. We could further\r\ndemonstrate
that depletion of ZO proteins within the YSL results in diminished actomyosin\r\nring
formation. This suggests that a mechanochemical feedback loop is at work during\r\nzebrafish
epiboly: ZO proteins help in proper actomyosin ring formation and actomyosin\r\ncontractility
and flows positively influence ZO-1 junctional recruitment. Finally, such a\r\nmesoscale
polarization process mediated through the flow of phase-separated protein\r\nclusters
might have implications for other processes such as immunological synapse\r\nformation,
C. elegans zygote polarization and wound healing."
acknowledged_ssus:
- _id: Bio
- _id: LifeSc
- _id: EM-Fac
- _id: SSU
alternative_title:
- ISTA Thesis
article_processing_charge: No
author:
- first_name: Cornelia
full_name: Schwayer, Cornelia
id: 3436488C-F248-11E8-B48F-1D18A9856A87
last_name: Schwayer
orcid: 0000-0001-5130-2226
citation:
ama: Schwayer C. Mechanosensation of tight junctions depends on ZO-1 phase separation
and flow. 2019. doi:10.15479/AT:ISTA:7186
apa: Schwayer, C. (2019). Mechanosensation of tight junctions depends on ZO-1
phase separation and flow. Institute of Science and Technology Austria. https://doi.org/10.15479/AT:ISTA:7186
chicago: Schwayer, Cornelia. “Mechanosensation of Tight Junctions Depends on ZO-1
Phase Separation and Flow.” Institute of Science and Technology Austria, 2019.
https://doi.org/10.15479/AT:ISTA:7186.
ieee: C. Schwayer, “Mechanosensation of tight junctions depends on ZO-1 phase separation
and flow,” Institute of Science and Technology Austria, 2019.
ista: Schwayer C. 2019. Mechanosensation of tight junctions depends on ZO-1 phase
separation and flow. Institute of Science and Technology Austria.
mla: Schwayer, Cornelia. Mechanosensation of Tight Junctions Depends on ZO-1
Phase Separation and Flow. Institute of Science and Technology Austria, 2019,
doi:10.15479/AT:ISTA:7186.
short: C. Schwayer, Mechanosensation of Tight Junctions Depends on ZO-1 Phase Separation
and Flow, Institute of Science and Technology Austria, 2019.
date_created: 2019-12-16T14:26:14Z
date_published: 2019-12-16T00:00:00Z
date_updated: 2023-09-07T12:56:42Z
day: '16'
ddc:
- '570'
degree_awarded: PhD
department:
- _id: CaHe
doi: 10.15479/AT:ISTA:7186
file:
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checksum: 585583c1c875c5d9525703a539668a7c
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creator: cschwayer
date_created: 2019-12-19T15:18:11Z
date_updated: 2020-07-14T12:47:52Z
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content_type: application/pdf
creator: cschwayer
date_created: 2019-12-19T15:19:21Z
date_updated: 2020-07-14T12:47:52Z
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file_name: Thesis_CS_final.pdf
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file_date_updated: 2020-07-14T12:47:52Z
has_accepted_license: '1'
language:
- iso: eng
month: '12'
oa: 1
oa_version: Published Version
page: '107'
publication_identifier:
issn:
- 2663-337X
publication_status: published
publisher: Institute of Science and Technology Austria
related_material:
record:
- id: '1096'
relation: dissertation_contains
status: public
- id: '7001'
relation: part_of_dissertation
status: public
status: public
supervisor:
- first_name: Carl-Philipp J
full_name: Heisenberg, Carl-Philipp J
id: 39427864-F248-11E8-B48F-1D18A9856A87
last_name: Heisenberg
orcid: 0000-0002-0912-4566
title: Mechanosensation of tight junctions depends on ZO-1 phase separation and flow
type: dissertation
user_id: c635000d-4b10-11ee-a964-aac5a93f6ac1
year: '2019'
...