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88 Publications

2017 | Journal Article | IST-REx-ID: 696 | OA
Stress induced mutagenesis: Stress diversity facilitates the persistence of mutator genes
M. Lukacisinova, S. Novak, T. Paixao, PLoS Computational Biology 13 (2017).
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2017 | Journal Article | IST-REx-ID: 704 | OA View | Files available | DOI
 
2017 | Journal Article | IST-REx-ID: 954 | OA
On the mechanistic nature of epistasis in a canonical cis-regulatory element
M. Lagator, T. Paixao, N.H. Barton, J.P. Bollback, C.C. Guet, ELife 6 (2017).
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2017 | Journal Article | IST-REx-ID: 1336 | OA
Towards a runtime comparison of natural and artificial evolution
T. Paixao, J. Pérez Heredia, D. Sudholt, B. Trubenova, Algorithmica 78 (2017) 681–713.
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2017 | Journal Article | IST-REx-ID: 1351 | OA
Model checking the evolution of gene regulatory networks
M. Giacobbe, C.C. Guet, A. Gupta, T.A. Henzinger, T. Paixao, T. Petrov, Acta Informatica 54 (2017) 765–787.
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2017 | Journal Article | IST-REx-ID: 1007 | OA
Zeros of nonlinear systems with input invariances
M. Lang, E. Sontag, Automatica 81C (2017) 46–55.
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2017 | Journal Article | IST-REx-ID: 1028 | OA
Green-light-induced inactivation of receptor signaling using cobalamin-binding domains
S. Kainrath, M. Stadler, E. Gschaider-Reichhart, M. Distel, H.L. Janovjak, Angewandte Chemie - International Edition 56 (2017) 4608–4611.
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2017 | Journal Article | IST-REx-ID: 1084
Insulation and wiring specificity of BceR like response regulators and their target promoters in Bacillus subtilis
C. Fang, A.A. Nagy-Staron, M. Grafe, R. Heermann, K. Jung, S. Gebhard, T. Mascher, Molecular Microbiology 104 (2017) 16–31.
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2016 | Conference Paper | IST-REx-ID: 1220 | OA
Fuselage boundary layer ingestion propulsion applied to a thin haul commuter aircraft for optimal efficiency
G. Mikić, A. Stoll, J. Bevirt, R. Grah, M. Moore, in:, AIAA, 2016, pp. 1–19.
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2016 | Conference Paper | IST-REx-ID: 1234 | OA
Faster statistical model checking for unbounded temporal properties
P. Daca, T.A. Henzinger, J. Kretinsky, T. Petrov, in:, Springer, 2016, pp. 112–129.
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2016 | Journal Article | IST-REx-ID: 1243
Bacterial autoimmunity due to a restriction-modification system
M. Pleska, L. Qian, R. Okura, T. Bergmiller, Y. Wakamoto, E. Kussell, C.C. Guet, Current Biology 26 (2016) 404–409.
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2016 | Journal Article | IST-REx-ID: 1250 | OA
Genetic manipulation of glycogen allocation affects replicative lifespan in E coli
A. Boehm, M. Arnoldini, T. Bergmiller, T. Röösli, C. Bigosch, M. Ackermann, PLoS Genetics 12 (2016).
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2016 | Journal Article | IST-REx-ID: 1290 | OA
Compounds that select against the tetracycline-resistance efflux pump
L. Stone, M. Baym, T. Lieberman, R.P. Chait, J. Clardy, R. Kishony, Nature Chemical Biology 12 (2016) 902–904.
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2016 | Conference Paper | IST-REx-ID: 1320 View | Files available | DOI
 
2016 | Journal Article | IST-REx-ID: 1332 | OA
Pervasive selection for and against antibiotic resistance in inhomogeneous multistress environments
R.P. Chait, A. Palmer, I. Yelin, R. Kishony, Nature Communications 7 (2016).
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2016 | Journal Article | IST-REx-ID: 1342 | OA
Spatiotemporal microbial evolution on antibiotic landscapes
M. Baym, T. Lieberman, E. Kelsic, R.P. Chait, R. Gross, I. Yelin, R. Kishony, Science 353 (2016) 1147–1151.
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2016 | Conference Paper | IST-REx-ID: 1349 | OA
When non-elitism outperforms elitism for crossing fitness valleys
P. Oliveto, T. Paixao, J. Heredia, D. Sudholt, B. Trubenova, in:, Proceedings of the Genetic and Evolutionary Computation Conference 2016 , ACM, 2016, pp. 1163–1170.
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2016 | Journal Article | IST-REx-ID: 1358 | OA
Intrinsic limits to gene regulation by global crosstalk
T. Friedlander, R. Prizak, C.C. Guet, N.H. Barton, G. Tkačik, Nature Communications 7 (2016).
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2016 | Journal Article | IST-REx-ID: 1359 | OA
The effect of gene interactions on the long-term response to selection
T. Paixao, N.H. Barton, PNAS 113 (2016) 4422–4427.
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2016 | Journal Article | IST-REx-ID: 1427 | OA
Epistatic interactions in the arabinose cis-regulatory element
M. Lagator, C. Igler, A. Moreno, C.C. Guet, J.P. Bollback, Molecular Biology and Evolution 33 (2016) 761–769.
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2016 | Conference Paper | IST-REx-ID: 1524 | OA
Efficient reduction of kappa models by static inspection of the rule-set
A. Beica, C.C. Guet, T. Petrov, in:, Springer, 2016, pp. 173–191.
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2016 | Journal Article | IST-REx-ID: 1008
An orthogonal permease–inducer–repressor feedback loop shows bistability
R. Gnügge, L. Dharmarajan, M. Lang, J. Stelling, ACS Synthetic Biology 5 (2016) 1098–1107.
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2016 | Conference Paper | IST-REx-ID: 1093 | OA
Linear distances between Markov chains
P. Daca, T.A. Henzinger, J. Kretinsky, T. Petrov, in:, Schloss Dagstuhl - Leibniz-Zentrum für Informatik, 2016.
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2016 | Journal Article | IST-REx-ID: 1170
Modular parameter identification of biomolecular networks
M. Lang, J. Stelling, SIAM Journal on Scientific Computing 38 (2016) B988–B1008.
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2015 | Journal Article | IST-REx-ID: 5749 | OA
Adaptation to Parasites and Costs of Parasite Resistance in Mutator and Nonmutator Bacteria
S. Wielgoss, T. Bergmiller, A.M. Bischofberger, A.R. Hall, Molecular Biology and Evolution 33 (2015) 770–782.
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2015 | Journal Article | IST-REx-ID: 1542 | OA
Toward a unifying framework for evolutionary processes
T. Paixao, G. Badkobeh, N.H. Barton, D. Çörüş, D. Dang, T. Friedrich, P. Lehre, D. Sudholt, A. Sutton, B. Trubenova, Journal of Theoretical Biology 383 (2015) 28–43.
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2015 | Journal Article | IST-REx-ID: 1666 | OA
Dynamics of transcription factor binding site evolution
M. Tugrul, T. Paixao, N.H. Barton, G. Tkačik, PLoS Genetics 11 (2015).
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2015 | Conference Paper | IST-REx-ID: 1835 | OA
Model checking gene regulatory networks
M. Giacobbe, C.C. Guet, A. Gupta, T.A. Henzinger, T. Paixao, T. Petrov, 9035 (2015) 469–483.
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2015 | Journal Article | IST-REx-ID: 1840 | OA
Optimal Kullback-Leibler aggregation via information bottleneck
B. Geiger, T. Petrov, G. Kubin, H. Koeppl, IEEE Transactions on Automatic Control 60 (2015) 1010–1022.
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2015 | Conference Paper | IST-REx-ID: 1430 | OA
First steps towards a runtime comparison of natural and artificial evolution
T. Paixao, D. Sudholt, J. Heredia, B. Trubenova, in:, Proceedings of the 2015 Annual Conference on Genetic and Evolutionary Computation, ACM, 2015, pp. 1455–1462.
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2014 | Journal Article | IST-REx-ID: 2036 | OA
Selection history and epistatic interactions impact dynamics of adaptation to novel environmental stresses
M. Lagator, N. Colegrave, P. Neve, Proceedings of the Royal Society of London Series B Biological Sciences 281 (2014).
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2014 | Journal Article | IST-REx-ID: 2056 | OA
Markov chain aggregation and its applications to combinatorial reaction networks
A. Ganguly, T. Petrov, H. Koeppl, Journal of Mathematical Biology 69 (2014) 767–797.
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2014 | Journal Article | IST-REx-ID: 2083 | OA
Role of sex and migration in adaptation to sink environments
M. Lagator, A. Morgan, P. Neve, N. Colegrave, Evolution 68 (2014) 2296–2305.
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2014 | Journal Article | IST-REx-ID: 1894 | OA
Functional and bioinformatics analysis of two Campylobacter jejuni homologs of the thiol-disulfide oxidoreductase, DsbA
A. Grabowska, E. Wywiał, S. Dunin Horkawicz, A. Łasica, M. Wösten, A.A. Nagy-Staron, R. Godlewska, K. Bocian Ostrzycka, K. Pieńkowska, P. Łaniewski, J. Bujnicki, J. Van Putten, E. Jagusztyn Krynicka, PLoS One 9 (2014).
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2014 | Journal Article | IST-REx-ID: 1913 | OA
Patterns of hippocampal tau pathology differentiate neurodegenerative dementias
I. Milenković, T. Petrov, G. Kovács, Dementia and Geriatric Cognitive Disorders 38 (2014) 375–388.
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2013 | Journal Article | IST-REx-ID: 499
Dynamic persistence of antibiotic-stressed mycobacteria
Y. Wakamoto, N. Dhar, R.P. Chait, K. Schneider, F. Signorino Gelo, S. Leibler, J. Mckinney, Science 339 (2013) 91–95.
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2013 | Conference Paper | IST-REx-ID: 2718 | OA
Can quantitative and population genetics help us understand evolutionary computation?
N.H. Barton, T. Paixao, in:, Proceedings of the 15th Annual Conference on Genetic and Evolutionary Computation, ACM, 2013, pp. 1573–1580.
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2013 | Conference Paper | IST-REx-ID: 2719
A variance decomposition approach to the analysis of genetic algorithms
T. Paixao, N.H. Barton, in:, Proceedings of the 15th Annual Conference on Genetic and Evolutionary Computation, ACM, 2013, pp. 845–852.
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2013 | Journal Article | IST-REx-ID: 2720 | OA
Accumulation of spontaneous mutations in the ciliate Tetrahymena thermophila
H. Long, T. Paixao, R. Azevedo, R. Zufall, Genetics 195 (2013) 527–540.
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2013 | Journal Article | IST-REx-ID: 2853 | OA
Altruism can evolve when relatedness is low: Evidence from bacteria committing suicide upon phage infection
D. Refardt, T. Bergmiller, R. Kümmerli, Proceedings of the Royal Society of London Series B Biological Sciences 280 (2013).
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2012 | Journal Article | IST-REx-ID: 2302
The propagation approach for computing biochemical reaction networks
T.A. Henzinger, M. Mateescu, IEEE ACM Transactions on Computational Biology and Bioinformatics 10 (2012) 310–322.
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2012 | Journal Article | IST-REx-ID: 2943 | OA
Variation of the folding and dynamics of the Escherichia coli chromosome with growth conditions
N. Hadizadeh Yazdi, C.C. Guet, R. Johnson, J. Marko, Molecular Microbiology 86 (2012) 1318–1333.
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2012 | Journal Article | IST-REx-ID: 3130 | OA
Patterns of evolutionary conservation of essential genes correlate with their compensability
T. Bergmiller, M. Ackermann, O. Silander, PLoS Genetics 8 (2012).
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2012 | Conference Paper | IST-REx-ID: 3136
Delayed continuous time Markov chains for genetic regulatory circuits
C.C. Guet, A. Gupta, T.A. Henzinger, M. Mateescu, A. Sezgin, in:, Springer, 2012, pp. 294–309.
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2011 | Journal Article | IST-REx-ID: 6496 | OA
Noise underlies switching behavior of the bacterial flagellum
H. Park, P. Oikonomou, C.C. Guet, P. Cluzel, Biophysical Journal 101 (2011) 2336–2340.
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2010 | Conference Paper | IST-REx-ID: 3719 | OA
Lumpability abstractions of rule-based systems
J. Feret, T.A. Henzinger, H. Koeppl, T. Petrov, in:, Open Publishing Association, 2010, pp. 142–161.
View | Files available | arXiv
 
2010 | Conference Paper | IST-REx-ID: 3847 | OA
SABRE: A tool for the stochastic analysis of biochemical reaction networks
F. Didier, T.A. Henzinger, M. Mateescu, V. Wolf, in:, IEEE, 2010, pp. 193–194.
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2009 | Conference Paper | IST-REx-ID: 3843 | OA
Fast adaptive uniformization of the chemical master equation
F. Didier, T.A. Henzinger, M. Mateescu, V. Wolf, in:, IEEE, 2009, pp. 118–127.
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