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126 Publications

2020 | Preprint | IST-REx-ID: 7675 | OA
R. Grah, B. Zoller, and G. Tkačik, “Normative models of enhancer function,” bioRxiv. Cold Spring Harbor Laboratory, 2020.
[Preprint] View | Files available | DOI | Download Preprint (ext.)
 
2020 | Journal Article | IST-REx-ID: 7569 | OA
R. Grah and T. Friedlander, “The relation between crosstalk and gene regulation form revisited,” PLOS Computational Biology, vol. 16, no. 2. Public Library of Science, 2020.
[Published Version] View | Files available | DOI | WoS
 
2020 | Research Data | IST-REx-ID: 8951 | OA
A. A. Nagy-Staron, “Sequences of gene regulatory network permutations for the article ‘Local genetic context shapes the function of a gene regulatory network.’” Institute of Science and Technology Austria, 2020.
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2020 | Research Data | IST-REx-ID: 7383 | OA
R. Grah, “Matlab scripts for the Paper: Gene Amplification as a Form of Population-Level Gene Expression regulation.” Institute of Science and Technology Austria, 2020.
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2020 | Thesis | IST-REx-ID: 7680 | OA
S. Kainrath, “Synthetic tools for optogenetic and chemogenetic inhibition of cellular signals,” Institute of Science and Technology Austria, 2020.
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2020 | Journal Article | IST-REx-ID: 7652 | OA
I. Tomanek et al., “Gene amplification as a form of population-level gene expression regulation,” Nature Ecology & Evolution, vol. 4, no. 4. Springer Nature, pp. 612–625, 2020.
[Submitted Version] View | Files available | DOI | WoS
 
2020 | Thesis | IST-REx-ID: 8653 | OA
I. Tomanek, “The evolution of gene expression by copy number and point mutations,” Institute of Science and Technology Austria, 2020.
[Published Version] View | Files available | DOI
 
2019 | Journal Article | IST-REx-ID: 6465 | OA
H. Chassin, M. Müller, M. Tigges, L. Scheller, M. Lang, and M. Fussenegger, “A modular degron library for synthetic circuits in mammalian cells,” Nature Communications, vol. 10, no. 1. Springer Nature, 2019.
[Published Version] View | Files available | DOI | WoS
 
2019 | Journal Article | IST-REx-ID: 6717 | OA
C. Igler and S. T. Abedon, “Commentary: A host-produced quorum-sensing autoinducer controls a phage lysis-lysogeny decision,” Frontiers in Microbiology, vol. 10. Frontiers, 2019.
[Published Version] View | Files available | DOI | WoS
 
2019 | Journal Article | IST-REx-ID: 6784 | OA
J. Ruess, M. Pleska, C. C. Guet, and G. Tkačik, “Molecular noise of innate immunity shapes bacteria-phage ecologies,” PLoS Computational Biology, vol. 15, no. 7. Public Library of Science, 2019.
[Published Version] View | Files available | DOI | WoS
 
2019 | Research Data Reference | IST-REx-ID: 9786
J. Ruess, M. Pleska, C. C. Guet, and G. Tkačik, “Supporting text and results.” Public Library of Science, 2019.
[Published Version] View | Files available | DOI
 
2019 | Conference Paper | IST-REx-ID: 7147
C. C. Guet, T. A. Henzinger, C. Igler, T. Petrov, and A. Sezgin, “Transient memory in gene regulation,” in 17th International Conference on Computational Methods in Systems Biology, Trieste, Italy, 2019, vol. 11773, pp. 155–187.
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2019 | Journal Article | IST-REx-ID: 138 | OA
N. Nikolic, “Autoregulation of bacterial gene expression: lessons from the MazEF toxin–antitoxin system,” Current Genetics, vol. 65, no. 1. Springer, pp. 133–138, 2019.
[Published Version] View | Files available | DOI | WoS
 
2019 | Journal Article | IST-REx-ID: 196 | OA
M. Lang and M. Shkolnikov, “Harmonic dynamics of the Abelian sandpile,” Proceedings of the National Academy of Sciences, vol. 116, no. 8. National Academy of Sciences, pp. 2821–2830, 2019.
[Published Version] View | Files available | DOI | Download Published Version (ext.) | WoS | PubMed | Europe PMC | arXiv
 
2019 | Research Data | IST-REx-ID: 7016 | OA
I. Tomanek, “Data for the paper ‘Gene amplification as a form of population-level gene expression regulation.’” Institute of Science and Technology Austria, 2019.
[Published Version] View | Files available | DOI
 
2019 | Thesis | IST-REx-ID: 6371 | OA
C. Igler, “On the nature of gene regulatory design - The biophysics of transcription factor binding shapes gene regulation,” Institute of Science and Technology Austria, 2019.
[Published Version] View | Files available | DOI
 
2018 | Journal Article | IST-REx-ID: 305
P. Misun, A. Birchler, M. Lang, A. Hierlemann, and O. Frey, “Fabrication and operation of microfluidic hanging drop networks,” Methods in Molecular Biology, vol. 1771. Springer, pp. 183–202, 2018.
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2018 | Journal Article | IST-REx-ID: 723 | OA
P. Oliveto, T. Paixao, J. Pérez Heredia, D. Sudholt, and B. Trubenova, “How to escape local optima in black box optimisation when non elitism outperforms elitism,” Algorithmica, vol. 80, no. 5. Springer, pp. 1604–1633, 2018.
[Published Version] View | Files available | DOI | WoS
 
2018 | Journal Article | IST-REx-ID: 503
K. Tomasek, T. Bergmiller, and C. C. Guet, “Lack of cations in flow cytometry buffers affect fluorescence signals by reducing membrane stability and viability of Escherichia coli strains,” Journal of Biotechnology, vol. 268. Elsevier, pp. 40–52, 2018.
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2018 | Journal Article | IST-REx-ID: 82 | OA
W. Chaudhry et al., “Leaky resistance and the conditions for the existence of lytic bacteriophage,” PLoS Biology, vol. 16, no. 8. Public Library of Science, 2018.
[Published Version] View | Files available | DOI | WoS
 
2018 | Research Data Reference | IST-REx-ID: 9810
W. Chaudhry et al., “Numerical data used in figures.” Public Library of Science, 2018.
[Published Version] View | Files available | DOI
 
2018 | Journal Article | IST-REx-ID: 457
M. Pleska, M. Lang, D. Refardt, B. Levin, and C. C. Guet, “Phage-host population dynamics promotes prophage acquisition in bacteria with innate immunity,” Nature Ecology and Evolution, vol. 2, no. 2. Springer Nature, pp. 359–366, 2018.
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2018 | Journal Article | IST-REx-ID: 5984 | OA
M. Morri et al., “Optical functionalization of human class A orphan G-protein-coupled receptors,” Nature Communications, vol. 9, no. 1. Springer Nature, 2018.
[Published Version] View | Files available | DOI | WoS
 
2018 | Journal Article | IST-REx-ID: 19 | OA
A. Palmer, R. P. Chait, and R. Kishony, “Nonoptimal gene expression creates latent potential for antibiotic resistance,” Molecular Biology and Evolution, vol. 35, no. 11. Oxford University Press, pp. 2669–2684, 2018.
[Submitted Version] View | DOI | Download Submitted Version (ext.) | WoS | PubMed | Europe PMC
 
2018 | Journal Article | IST-REx-ID: 438 | OA
N. Nikolic, T. Bergmiller, A. Vandervelde, T. Albanese, L. Gelens, and I. Moll, “Autoregulation of mazEF expression underlies growth heterogeneity in bacterial populations,” Nucleic Acids Research, vol. 46, no. 6. Oxford University Press, pp. 2918–2931, 2018.
[Published Version] View | Files available | DOI | WoS
 
2018 | Research Data | IST-REx-ID: 5569 | OA
T. Bergmiller and N. Nikolic, “Time-lapse microscopy data.” Institute of Science and Technology Austria, 2018.
[Published Version] View | Files available | DOI
 
2018 | Journal Article | IST-REx-ID: 161 | OA
D. De Martino, A. A. Mc, T. Bergmiller, C. C. Guet, and G. Tkačik, “Statistical mechanics for metabolic networks during steady state growth,” Nature Communications, vol. 9, no. 1. Springer Nature, 2018.
[Published Version] View | Files available | DOI | WoS
 
2018 | Thesis | IST-REx-ID: 26 | OA
M. Steinrück, “The influence of sequence context on the evolution of bacterial gene expression,” Institute of Science and Technology Austria, 2018.
[Published Version] View | Files available | DOI
 
2018 | Journal Article | IST-REx-ID: 67 | OA
C. Igler, M. Lagator, G. Tkačik, J. P. Bollback, and C. C. Guet, “Evolutionary potential of transcription factors for gene regulatory rewiring,” Nature Ecology and Evolution, vol. 2, no. 10. Nature Publishing Group, pp. 1633–1643, 2018.
[Submitted Version] View | Files available | DOI | WoS
 
2018 | Research Data | IST-REx-ID: 5585 | OA
C. Igler, M. Lagator, G. Tkačik, J. P. Bollback, and C. C. Guet, “Data for the paper Evolutionary potential of transcription factors for gene regulatory rewiring.” Institute of Science and Technology Austria, 2018.
[Published Version] View | Files available | DOI
 
2017 | Journal Article | IST-REx-ID: 538 | OA
S. Kainrath, M. Stadler, E. Gschaider-Reichhart, M. Distel, and H. L. Janovjak, “Grünlicht-induzierte Rezeptorinaktivierung durch Cobalamin-bindende Domänen,” Angewandte Chemie, vol. 129, no. 16. Wiley, pp. 4679–4682, 2017.
[Published Version] View | Files available | DOI
 
2017 | Journal Article | IST-REx-ID: 570 | OA
M. Lagator, S. Sarikas, H. Acar, J. P. Bollback, and C. C. Guet, “Regulatory network structure determines patterns of intermolecular epistasis,” eLife, vol. 6. eLife Sciences Publications, 2017.
[Published Version] View | Files available | DOI
 
2017 | Journal Article | IST-REx-ID: 613 | OA
R. P. Chait, J. Ruess, T. Bergmiller, G. Tkačik, and C. C. Guet, “Shaping bacterial population behavior through computer interfaced control of individual cells,” Nature Communications, vol. 8, no. 1. Nature Publishing Group, 2017.
[Published Version] View | Files available | DOI
 
2017 | Journal Article | IST-REx-ID: 624 | OA
N. Nikolic, Z. Didara, and I. Moll, “MazF activation promotes translational heterogeneity of the grcA mRNA in Escherichia coli populations,” PeerJ, vol. 2017, no. 9. PeerJ, 2017.
[Published Version] View | Files available | DOI
 
2017 | Journal Article | IST-REx-ID: 655 | OA
T. Renault et al., “Bacterial flagella grow through an injection diffusion mechanism,” eLife, vol. 6. eLife Sciences Publications, 2017.
[Published Version] View | Files available | DOI
 
2017 | Journal Article | IST-REx-ID: 541 | OA
N. Nikolic et al., “Cell-to-cell variation and specialization in sugar metabolism in clonal bacterial populations,” PLoS Genetics, vol. 13, no. 12. Public Library of Science, 2017.
[Published Version] View | Files available | DOI
 
2017 | Research Data Reference | IST-REx-ID: 9847 | OA
M. Pleska and C. C. Guet, “Supplementary materials and methods; Full data set from effects of mutations in phage restriction sites during escape from restriction–modification.” The Royal Society, 2017.
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2017 | Research Data Reference | IST-REx-ID: 9845
N. Nikolic et al., “Mathematical model.” Public Library of Science, 2017.
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2017 | Research Data Reference | IST-REx-ID: 9849
M. Lukacisinova, S. Novak, and T. Paixao, “Modelling and simulation details.” Public Library of Science, 2017.
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2017 | Research Data Reference | IST-REx-ID: 9850
M. Lukacisinova, S. Novak, and T. Paixao, “Extensions of the model.” Public Library of Science, 2017.
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2017 | Research Data Reference | IST-REx-ID: 9846
N. Nikolic et al., “Supplementary methods.” Public Library of Science, 2017.
[Published Version] View | Files available | DOI
 
2017 | Research Data Reference | IST-REx-ID: 9851
M. Lukacisinova, S. Novak, and T. Paixao, “Heuristic prediction for multiple stresses.” Public Library of Science, 2017.
[Published Version] View | Files available | DOI
 
2017 | Research Data Reference | IST-REx-ID: 9852
M. Lukacisinova, S. Novak, and T. Paixao, “Resistance frequencies for different combination strategies.” Public Library of Science, 2017.
[Published Version] View | Files available | DOI
 
2017 | Research Data Reference | IST-REx-ID: 9844
N. Nikolic et al., “Source data for figures and tables.” Public Library of Science, 2017.
[Published Version] View | Files available | DOI
 
2017 | Journal Article | IST-REx-ID: 561 | OA
M. Pleska and C. C. Guet, “Effects of mutations in phage restriction sites during escape from restriction–modification,” Biology Letters, vol. 13, no. 12. The Royal Society, 2017.
[Published Version] View | Files available | DOI | Download Published Version (ext.) | PubMed | Europe PMC
 
2017 | Thesis | IST-REx-ID: 202 | OA
M. Pleska, “Biology of restriction-modification systems at the single-cell and population level,” Institute of Science and Technology Austria, 2017.
[Published Version] View | Files available | DOI
 
2017 | Journal Article | IST-REx-ID: 1351 | OA
M. Giacobbe, C. C. Guet, A. Gupta, T. A. Henzinger, T. Paixao, and T. Petrov, “Model checking the evolution of gene regulatory networks,” Acta Informatica, vol. 54, no. 8. Springer, pp. 765–787, 2017.
[Published Version] View | Files available | DOI | WoS
 
2017 | Journal Article | IST-REx-ID: 1336 | OA
T. Paixao, J. Pérez Heredia, D. Sudholt, and B. Trubenova, “Towards a runtime comparison of natural and artificial evolution,” Algorithmica, vol. 78, no. 2. Springer, pp. 681–713, 2017.
[Published Version] View | Files available | DOI | WoS
 
2017 | Journal Article | IST-REx-ID: 1084
C. Fang et al., “Insulation and wiring specificity of BceR like response regulators and their target promoters in Bacillus subtilis,” Molecular Microbiology, vol. 104, no. 1. Wiley-Blackwell, pp. 16–31, 2017.
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2017 | Journal Article | IST-REx-ID: 954 | OA
M. Lagator, T. Paixao, N. H. Barton, J. P. Bollback, and C. C. Guet, “On the mechanistic nature of epistasis in a canonical cis-regulatory element,” eLife, vol. 6. eLife Sciences Publications, 2017.
[Published Version] View | Files available | DOI | WoS
 

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