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120 Publications
2022 | Journal Article | IST-REx-ID: 10736 |

Predicting bacterial promoter function and evolution from random sequences
M. Lagator, S. Sarikas, M. Steinrueck, D. Toledo-Aparicio, J.P. Bollback, C.C. Guet, G. Tkačik, ELife 11 (2022).
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| PubMed | Europe PMC
M. Lagator, S. Sarikas, M. Steinrueck, D. Toledo-Aparicio, J.P. Bollback, C.C. Guet, G. Tkačik, ELife 11 (2022).
2022 | Journal Article | IST-REx-ID: 10812
The physiology and genetics of bacterial responses to antibiotic combinations
R. Römhild, M.T. Bollenbach, D.I. Andersson, Nature Reviews Microbiology (2022).
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| DOI
R. Römhild, M.T. Bollenbach, D.I. Andersson, Nature Reviews Microbiology (2022).
2022 | Journal Article | IST-REx-ID: 10939 |

Parameter inference for stochastic biochemical models from perturbation experiments parallelised at the single cell level
A. Davidović, R.P. Chait, G. Batt, J. Ruess, PLoS Computational Biology 18 (2022).
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A. Davidović, R.P. Chait, G. Batt, J. Ruess, PLoS Computational Biology 18 (2022).
2022 | Journal Article | IST-REx-ID: 11339 |

Nutrient and salt depletion synergistically boosts glucose metabolism in individual Escherichia coli cells
G. Glover, M. Voliotis, U. Łapińska, B.M. Invergo, D. Soanes, P. O’Neill, K. Moore, N. Nikolic, P. Petrov, D.S. Milner, S. Roy, K. Heesom, T.A. Richards, K. Tsaneva-Atanasova, S. Pagliara, Communications Biology 5 (2022).
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G. Glover, M. Voliotis, U. Łapińska, B.M. Invergo, D. Soanes, P. O’Neill, K. Moore, N. Nikolic, P. Petrov, D.S. Milner, S. Roy, K. Heesom, T.A. Richards, K. Tsaneva-Atanasova, S. Pagliara, Communications Biology 5 (2022).
2021 | Journal Article | IST-REx-ID: 9046 |

Mechanisms and therapeutic potential of collateral sensitivity to antibiotics
R. Römhild, D.I. Andersson, PLoS Pathogens 17 (2021).
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| PubMed | Europe PMC
R. Römhild, D.I. Andersson, PLoS Pathogens 17 (2021).
2021 | Journal Article | IST-REx-ID: 9283 |

Local genetic context shapes the function of a gene regulatory network
A.A. Nagy-Staron, K. Tomasek, C. Caruso Carter, E. Sonnleitner, B. Kavcic, T. Paixão, C.C. Guet, ELife 10 (2021).
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A.A. Nagy-Staron, K. Tomasek, C. Caruso Carter, E. Sonnleitner, B. Kavcic, T. Paixão, C.C. Guet, ELife 10 (2021).
2021 | Thesis | IST-REx-ID: 10307
Pathogenic Escherichia coli hijack the host immune response
K. Tomasek, Pathogenic Escherichia Coli Hijack the Host Immune Response, IST Austria, 2021.
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K. Tomasek, Pathogenic Escherichia Coli Hijack the Host Immune Response, IST Austria, 2021.
2021 | Preprint | IST-REx-ID: 10316 |

Type 1 piliated uropathogenic Escherichia coli hijack the host immune response by binding to CD14
K. Tomasek, A.F. Leithner, I. Glatzová, M.S. Lukesch, C.C. Guet, M.K. Sixt, BioRxiv (n.d.).
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K. Tomasek, A.F. Leithner, I. Glatzová, M.S. Lukesch, C.C. Guet, M.K. Sixt, BioRxiv (n.d.).
2021 | Journal Article | IST-REx-ID: 9746 |

High potency of sequential therapy with only beta-lactam antibiotics
A. Batra, R. Römhild, E. Rousseau, S. Franzenburg, S. Niemann, H. Schulenburg, ELife 10 (2021).
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A. Batra, R. Römhild, E. Rousseau, S. Franzenburg, S. Niemann, H. Schulenburg, ELife 10 (2021).
2021 | Journal Article | IST-REx-ID: 9822 |

Sequential and switchable patterning for studying cellular processes under spatiotemporal control
T. Zisis, J. Schwarz, M. Balles, M. Kretschmer, M. Nemethova, R.P. Chait, R. Hauschild, J. Lange, C.C. Guet, M.K. Sixt, S. Zahler, ACS Applied Materials and Interfaces 13 (2021) 35545–35560.
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T. Zisis, J. Schwarz, M. Balles, M. Kretschmer, M. Nemethova, R.P. Chait, R. Hauschild, J. Lange, C.C. Guet, M.K. Sixt, S. Zahler, ACS Applied Materials and Interfaces 13 (2021) 35545–35560.
2021 | Journal Article | IST-REx-ID: 9647 |

Long lived transients in gene regulation
T. Petrov, C. Igler, A. Sezgin, T.A. Henzinger, C.C. Guet, Theoretical Computer Science 893 (2021) 1–16.
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T. Petrov, C. Igler, A. Sezgin, T.A. Henzinger, C.C. Guet, Theoretical Computer Science 893 (2021) 1–16.
2021 | Journal Article | IST-REx-ID: 10363 |

Rational engineering of an erythropoietin fusion protein to treat hypoxia
J. Lee, A. Vernet, N. Gruber, K.M. Kready, D.R. Burrill, J.C. Way, P.A. Silver, Protein Engineering, Design and Selection 34 (2021).
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J. Lee, A. Vernet, N. Gruber, K.M. Kready, D.R. Burrill, J.C. Way, P.A. Silver, Protein Engineering, Design and Selection 34 (2021).
2020 | Thesis | IST-REx-ID: 8155 |

Gene regulation across scales – how biophysical constraints shape evolution
R. Grah, Gene Regulation across Scales – How Biophysical Constraints Shape Evolution, IST Austria, 2020.
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R. Grah, Gene Regulation across Scales – How Biophysical Constraints Shape Evolution, IST Austria, 2020.
2020 | Book Chapter | IST-REx-ID: 8173
Design and application of light-regulated receptor tyrosine kinases
S. Kainrath, H.L. Janovjak, in:, D. Niopek (Ed.), Photoswitching Proteins, Springer Nature, 2020, pp. 233–246.
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| DOI
S. Kainrath, H.L. Janovjak, in:, D. Niopek (Ed.), Photoswitching Proteins, Springer Nature, 2020, pp. 233–246.
2020 | Research Data | IST-REx-ID: 7383 |

Matlab scripts for the Paper: Gene Amplification as a Form of Population-Level Gene Expression regulation
R. Grah, (2020).
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R. Grah, (2020).
2020 | Journal Article | IST-REx-ID: 7569 |

The relation between crosstalk and gene regulation form revisited
R. Grah, T. Friedlander, PLOS Computational Biology 16 (2020).
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R. Grah, T. Friedlander, PLOS Computational Biology 16 (2020).
2020 | Preprint | IST-REx-ID: 7675 |

Normative models of enhancer function
R. Grah, B. Zoller, G. Tkačik, BioRxiv (2020).
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R. Grah, B. Zoller, G. Tkačik, BioRxiv (2020).
2020 | Research Data | IST-REx-ID: 8951 |

Sequences of gene regulatory network permutations for the article "Local genetic context shapes the function of a gene regulatory network"
A.A. Nagy-Staron, (2020).
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A.A. Nagy-Staron, (2020).
2020 | Thesis | IST-REx-ID: 7680 |

Synthetic tools for optogenetic and chemogenetic inhibition of cellular signals
S. Kainrath, Synthetic Tools for Optogenetic and Chemogenetic Inhibition of Cellular Signals, IST Austria, 2020.
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S. Kainrath, Synthetic Tools for Optogenetic and Chemogenetic Inhibition of Cellular Signals, IST Austria, 2020.
2020 | Journal Article | IST-REx-ID: 7652 |

Gene amplification as a form of population-level gene expression regulation
I. Tomanek, R. Grah, M. Lagator, A.M.C. Andersson, J.P. Bollback, G. Tkačik, C.C. Guet, Nature Ecology & Evolution 4 (2020) 612–625.
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I. Tomanek, R. Grah, M. Lagator, A.M.C. Andersson, J.P. Bollback, G. Tkačik, C.C. Guet, Nature Ecology & Evolution 4 (2020) 612–625.