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83 Publications

2020 | Journal Article | IST-REx-ID: 7569 | OA
The relation between crosstalk and gene regulation form revisited
R. Grah, T. Friedlander, PLOS Computational Biology 16 (2020).
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2020 | Preprint | IST-REx-ID: 7675 | OA
Normative models of enhancer function
R. Grah, B. Zoller, G. Tkačik, BioRxiv (2020).
View | Files available | Download Preprint (ext.)
 
2020 | Thesis | IST-REx-ID: 7680
Synthetic tools for optogenetic and chemogenetic inhibition of cellular signals
S. Kainrath, Synthetic Tools for Optogenetic and Chemogenetic Inhibition of Cellular Signals, IST Austria, 2020.
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2020 | Book Chapter | IST-REx-ID: 8173
Design and application of light-regulated receptor tyrosine kinases
S. Kainrath, H.L. Janovjak, in:, D. Niopek (Ed.), Photoswitching Proteins, Springer Nature, 2020, pp. 233–246.
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2020 | Thesis | IST-REx-ID: 8155 | OA
Gene regulation across scales – how biophysical constraints shape evolution
R. Grah, Gene Regulation across Scales – How Biophysical Constraints Shape Evolution, IST Austria, 2020.
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2020 | Journal Article | IST-REx-ID: 7652 | OA
Gene amplification as a form of population-level gene expression regulation
I. Tomanek, R. Grah, M. Lagator, A.M.C. Andersson, J.P. Bollback, G. Tkačik, C.C. Guet, Nature Ecology & Evolution 4 (2020) 612–625.
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2020 | Thesis | IST-REx-ID: 8653
The evolution of gene expression by copy number and point mutations
I. Tomanek, The Evolution of Gene Expression by Copy Number and Point Mutations, IST Austria, 2020.
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2019 | Conference Paper | IST-REx-ID: 7147
Transient memory in gene regulation
C.C. Guet, T.A. Henzinger, C. Igler, T. Petrov, A. Sezgin, in:, 17th International Conference on Computational Methods in Systems Biology, Springer Nature, 2019, pp. 155–187.
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2019 | Thesis | IST-REx-ID: 6371 | OA
On the nature of gene regulatory design - The biophysics of transcription factor binding shapes gene regulation
C. Igler, On the Nature of Gene Regulatory Design - The Biophysics of Transcription Factor Binding Shapes Gene Regulation, IST Austria, 2019.
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2019 | Journal Article | IST-REx-ID: 6465 | OA
A modular degron library for synthetic circuits in mammalian cells
H. Chassin, M. Müller, M. Tigges, L. Scheller, M. Lang, M. Fussenegger, Nature Communications 10 (2019).
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2019 | Journal Article | IST-REx-ID: 6717 | OA View | Files available | DOI
 
2019 | Journal Article | IST-REx-ID: 6784 | OA
Molecular noise of innate immunity shapes bacteria-phage ecologies
J. Ruess, M. Pleska, C.C. Guet, G. Tkačik, PLoS Computational Biology 15 (2019).
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2019 | Journal Article | IST-REx-ID: 196 | OA
Harmonic dynamics of the Abelian sandpile
M. Lang, M. Shkolnikov, Proceedings of the National Academy of Sciences 116 (2019) 2821–2830.
View | Files available | DOI | Download Published Version (ext.) | PubMed | Europe PMC | arXiv
 
2019 | Journal Article | IST-REx-ID: 138 | OA View | Files available | DOI
 
2018 | Thesis | IST-REx-ID: 26 | OA
The influence of sequence context on the evolution of bacterial gene expression
M. Steinrück, The Influence of Sequence Context on the Evolution of Bacterial Gene Expression, IST Austria, 2018.
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2018 | Journal Article | IST-REx-ID: 723 | OA
How to escape local optima in black box optimisation when non elitism outperforms elitism
P. Oliveto, T. Paixao, J. Pérez Heredia, D. Sudholt, B. Trubenova, Algorithmica 80 (2018) 1604–1633.
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2018 | Journal Article | IST-REx-ID: 438 | OA
Autoregulation of mazEF expression underlies growth heterogeneity in bacterial populations
N. Nikolic, T. Bergmiller, A. Vandervelde, T. Albanese, L. Gelens, I. Moll, Nucleic Acids Research 46 (2018) 2918–2931.
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2018 | Journal Article | IST-REx-ID: 457
Phage-host population dynamics promotes prophage acquisition in bacteria with innate immunity
M. Pleska, M. Lang, D. Refardt, B. Levin, C.C. Guet, Nature Ecology and Evolution 2 (2018) 359–366.
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2018 | Journal Article | IST-REx-ID: 503 View | DOI
 
2018 | Journal Article | IST-REx-ID: 5984 | OA
Optical functionalization of human class A orphan G-protein-coupled receptors
M. Morri, I. Sanchez-Romero, A.-M. Tichy, S. Kainrath, E.J. Gerrard, P. Hirschfeld, J. Schwarz, H.L. Janovjak, Nature Communications 9 (2018).
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