---
_id: '8699'
abstract:
- lang: eng
text: In the high spin–orbit-coupled Sr2IrO4, the high sensitivity of the ground
state to the details of the local lattice structure shows a large potential for
the manipulation of the functional properties by inducing local lattice distortions.
We use epitaxial strain to modify the Ir–O bond geometry in Sr2IrO4 and perform
momentum-dependent resonant inelastic X-ray scattering (RIXS) at the metal and
at the ligand sites to unveil the response of the low-energy elementary excitations.
We observe that the pseudospin-wave dispersion for tensile-strained Sr2IrO4 films
displays large softening along the [h,0] direction, while along the [h,h] direction
it shows hardening. This evolution reveals a renormalization of the magnetic interactions
caused by a strain-driven cross-over from anisotropic to isotropic interactions
between the magnetic moments. Moreover, we detect dispersive electron–hole pair
excitations which shift to lower (higher) energies upon compressive (tensile)
strain, manifesting a reduction (increase) in the size of the charge gap. This
behavior shows an intimate coupling between charge excitations and lattice distortions
in Sr2IrO4, originating from the modified hopping elements between the t2g orbitals.
Our work highlights the central role played by the lattice degrees of freedom
in determining both the pseudospin and charge excitations of Sr2IrO4 and provides
valuable information toward the control of the ground state of complex oxides
in the presence of high spin–orbit coupling.
acknowledgement: 'We gratefully acknowledge C. Sahle for experimental support at the
ID20 beamline of the ESRF. The soft X-ray experiments were carried out at the ADRESS
beamline of the Swiss Light Source, Paul Scherrer Institut (PSI). E. Paris and T.S.
thank X. Lu and C. Monney for valuable discussions. The work at PSI is supported
by the Swiss National Science Foundation (SNSF) through Project 200021_178867, the
NCCR (National Centre of Competence in Research) MARVEL (Materials’ Revolution:
Computational Design and Discovery of Novel Materials) and the Sinergia network
Mott Physics Beyond the Heisenberg Model (MPBH) (SNSF Research Grants CRSII2_160765/1
and CRSII2_141962). K.W. acknowledges support by the Narodowe Centrum Nauki Projects
2016/22/E/ST3/00560 and 2016/23/B/ST3/00839. E.M.P. and M.N. acknowledge funding
from the European Union’s Horizon 2020 research and innovation programme under the
Marie Sklodowska-Curie Grant Agreements 754411 and 701647, respectively. M.R. was
supported by the Swiss National Science Foundation under Project 200021 – 182695.
This research used resources of the APS, a U.S. Department of Energy (DOE) Office
of Science User Facility operated for the DOE Office of Science by Argonne National
Laboratory under Contract DE-AC02-06CH11357.'
article_processing_charge: No
article_type: original
author:
- first_name: Eugenio
full_name: Paris, Eugenio
last_name: Paris
- first_name: Yi
full_name: Tseng, Yi
last_name: Tseng
- first_name: Ekaterina
full_name: Paerschke, Ekaterina
id: 8275014E-6063-11E9-9B7F-6338E6697425
last_name: Paerschke
orcid: 0000-0003-0853-8182
- first_name: Wenliang
full_name: Zhang, Wenliang
last_name: Zhang
- first_name: Mary H
full_name: Upton, Mary H
last_name: Upton
- first_name: Anna
full_name: Efimenko, Anna
last_name: Efimenko
- first_name: Katharina
full_name: Rolfs, Katharina
last_name: Rolfs
- first_name: Daniel E
full_name: McNally, Daniel E
last_name: McNally
- first_name: Laura
full_name: Maurel, Laura
last_name: Maurel
- first_name: Muntaser
full_name: Naamneh, Muntaser
last_name: Naamneh
- first_name: Marco
full_name: Caputo, Marco
last_name: Caputo
- first_name: Vladimir N
full_name: Strocov, Vladimir N
last_name: Strocov
- first_name: Zhiming
full_name: Wang, Zhiming
last_name: Wang
- first_name: Diego
full_name: Casa, Diego
last_name: Casa
- first_name: Christof W
full_name: Schneider, Christof W
last_name: Schneider
- first_name: Ekaterina
full_name: Pomjakushina, Ekaterina
last_name: Pomjakushina
- first_name: Krzysztof
full_name: Wohlfeld, Krzysztof
last_name: Wohlfeld
- first_name: Milan
full_name: Radovic, Milan
last_name: Radovic
- first_name: Thorsten
full_name: Schmitt, Thorsten
last_name: Schmitt
citation:
ama: Paris E, Tseng Y, Paerschke E, et al. Strain engineering of the charge and
spin-orbital interactions in Sr2IrO4. Proceedings of the National Academy of
Sciences of the United States of America. 2020;117(40):24764-24770. doi:10.1073/pnas.2012043117
apa: Paris, E., Tseng, Y., Paerschke, E., Zhang, W., Upton, M. H., Efimenko, A.,
… Schmitt, T. (2020). Strain engineering of the charge and spin-orbital interactions
in Sr2IrO4. Proceedings of the National Academy of Sciences of the United States
of America. National Academy of Sciences. https://doi.org/10.1073/pnas.2012043117
chicago: Paris, Eugenio, Yi Tseng, Ekaterina Paerschke, Wenliang Zhang, Mary H Upton,
Anna Efimenko, Katharina Rolfs, et al. “Strain Engineering of the Charge and Spin-Orbital
Interactions in Sr2IrO4.” Proceedings of the National Academy of Sciences of
the United States of America. National Academy of Sciences, 2020. https://doi.org/10.1073/pnas.2012043117.
ieee: E. Paris et al., “Strain engineering of the charge and spin-orbital
interactions in Sr2IrO4,” Proceedings of the National Academy of Sciences of
the United States of America, vol. 117, no. 40. National Academy of Sciences,
pp. 24764–24770, 2020.
ista: Paris E, Tseng Y, Paerschke E, Zhang W, Upton MH, Efimenko A, Rolfs K, McNally
DE, Maurel L, Naamneh M, Caputo M, Strocov VN, Wang Z, Casa D, Schneider CW, Pomjakushina
E, Wohlfeld K, Radovic M, Schmitt T. 2020. Strain engineering of the charge and
spin-orbital interactions in Sr2IrO4. Proceedings of the National Academy of Sciences
of the United States of America. 117(40), 24764–24770.
mla: Paris, Eugenio, et al. “Strain Engineering of the Charge and Spin-Orbital Interactions
in Sr2IrO4.” Proceedings of the National Academy of Sciences of the United
States of America, vol. 117, no. 40, National Academy of Sciences, 2020, pp.
24764–70, doi:10.1073/pnas.2012043117.
short: E. Paris, Y. Tseng, E. Paerschke, W. Zhang, M.H. Upton, A. Efimenko, K. Rolfs,
D.E. McNally, L. Maurel, M. Naamneh, M. Caputo, V.N. Strocov, Z. Wang, D. Casa,
C.W. Schneider, E. Pomjakushina, K. Wohlfeld, M. Radovic, T. Schmitt, Proceedings
of the National Academy of Sciences of the United States of America 117 (2020)
24764–24770.
date_created: 2020-10-25T23:01:17Z
date_published: 2020-10-06T00:00:00Z
date_updated: 2023-08-22T12:11:52Z
day: '06'
ddc:
- '530'
department:
- _id: MiLe
doi: 10.1073/pnas.2012043117
ec_funded: 1
external_id:
arxiv:
- '2009.12262'
isi:
- '000579059100029'
pmid:
- '32958669'
file:
- access_level: open_access
checksum: 1638fa36b442e2868576c6dd7d6dc505
content_type: application/pdf
creator: cziletti
date_created: 2020-10-28T11:53:12Z
date_updated: 2020-10-28T11:53:12Z
file_id: '8715'
file_name: 2020_PNAS_Paris.pdf
file_size: 1176522
relation: main_file
success: 1
file_date_updated: 2020-10-28T11:53:12Z
has_accepted_license: '1'
intvolume: ' 117'
isi: 1
issue: '40'
language:
- iso: eng
month: '10'
oa: 1
oa_version: Published Version
page: 24764-24770
pmid: 1
project:
- _id: 260C2330-B435-11E9-9278-68D0E5697425
call_identifier: H2020
grant_number: '754411'
name: ISTplus - Postdoctoral Fellowships
publication: Proceedings of the National Academy of Sciences of the United States
of America
publication_identifier:
eissn:
- '10916490'
issn:
- '00278424'
publication_status: published
publisher: National Academy of Sciences
quality_controlled: '1'
scopus_import: '1'
status: public
title: Strain engineering of the charge and spin-orbital interactions in Sr2IrO4
tmp:
image: /images/cc_by_nc_nd.png
legal_code_url: https://creativecommons.org/licenses/by-nc-nd/4.0/legalcode
name: Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International
(CC BY-NC-ND 4.0)
short: CC BY-NC-ND (4.0)
type: journal_article
user_id: 4359f0d1-fa6c-11eb-b949-802e58b17ae8
volume: 117
year: '2020'
...
---
_id: '8737'
abstract:
- lang: eng
text: Mitochondrial complex I couples NADH:ubiquinone oxidoreduction to proton pumping
by an unknown mechanism. Here, we present cryo-electron microscopy structures
of ovine complex I in five different conditions, including turnover, at resolutions
up to 2.3 to 2.5 angstroms. Resolved water molecules allowed us to experimentally
define the proton translocation pathways. Quinone binds at three positions along
the quinone cavity, as does the inhibitor rotenone that also binds within subunit
ND4. Dramatic conformational changes around the quinone cavity couple the redox
reaction to proton translocation during open-to-closed state transitions of the
enzyme. In the induced deactive state, the open conformation is arrested by the
ND6 subunit. We propose a detailed molecular coupling mechanism of complex I,
which is an unexpected combination of conformational changes and electrostatic
interactions.
acknowledged_ssus:
- _id: LifeSc
- _id: EM-Fac
acknowledgement: We thank J. Novacek (CEITEC Brno) and V.-V. Hodirnau (IST Austria)
for their help with collecting cryo-EM datasets. We thank the IST Life Science and
Electron Microscopy Facilities for providing equipment. This work has been supported
by iNEXT,project number 653706, funded by the Horizon 2020 program of the European
Union. This article reflects only the authors’view,and the European Commission is
not responsible for any use that may be made of the information it contains. CIISB
research infrastructure project LM2015043 funded by MEYS CR is gratefully acknowledged
for the financial support of the measurements at the CF Cryo-electron Microscopy
and Tomography CEITEC MU.This project has received funding from the European Union’s
Horizon 2020 research and innovation program under the Marie Skłodowska-Curie Grant
Agreement no. 665385
article_number: eabc4209
article_processing_charge: No
article_type: original
author:
- first_name: Domen
full_name: Kampjut, Domen
id: 37233050-F248-11E8-B48F-1D18A9856A87
last_name: Kampjut
- first_name: Leonid A
full_name: Sazanov, Leonid A
id: 338D39FE-F248-11E8-B48F-1D18A9856A87
last_name: Sazanov
orcid: 0000-0002-0977-7989
citation:
ama: Kampjut D, Sazanov LA. The coupling mechanism of mammalian respiratory complex
I. Science. 2020;370(6516). doi:10.1126/science.abc4209
apa: Kampjut, D., & Sazanov, L. A. (2020). The coupling mechanism of mammalian
respiratory complex I. Science. American Association for the Advancement
of Science. https://doi.org/10.1126/science.abc4209
chicago: Kampjut, Domen, and Leonid A Sazanov. “The Coupling Mechanism of Mammalian
Respiratory Complex I.” Science. American Association for the Advancement
of Science, 2020. https://doi.org/10.1126/science.abc4209.
ieee: D. Kampjut and L. A. Sazanov, “The coupling mechanism of mammalian respiratory
complex I,” Science, vol. 370, no. 6516. American Association for the Advancement
of Science, 2020.
ista: Kampjut D, Sazanov LA. 2020. The coupling mechanism of mammalian respiratory
complex I. Science. 370(6516), eabc4209.
mla: Kampjut, Domen, and Leonid A. Sazanov. “The Coupling Mechanism of Mammalian
Respiratory Complex I.” Science, vol. 370, no. 6516, eabc4209, American
Association for the Advancement of Science, 2020, doi:10.1126/science.abc4209.
short: D. Kampjut, L.A. Sazanov, Science 370 (2020).
date_created: 2020-11-08T23:01:23Z
date_published: 2020-10-30T00:00:00Z
date_updated: 2023-08-22T12:35:38Z
day: '30'
ddc:
- '572'
department:
- _id: LeSa
doi: 10.1126/science.abc4209
ec_funded: 1
external_id:
isi:
- '000583031800004'
pmid:
- '32972993'
file:
- access_level: open_access
checksum: 658ba90979ca9528a2efdfac8547047a
content_type: application/pdf
creator: lsazanov
date_created: 2020-11-26T18:47:58Z
date_updated: 2020-11-26T18:47:58Z
file_id: '8820'
file_name: Full_manuscript_with_SI_opt_red.pdf
file_size: 7618987
relation: main_file
success: 1
file_date_updated: 2020-11-26T18:47:58Z
has_accepted_license: '1'
intvolume: ' 370'
isi: 1
issue: '6516'
language:
- iso: eng
month: '10'
oa: 1
oa_version: Submitted Version
pmid: 1
project:
- _id: 2564DBCA-B435-11E9-9278-68D0E5697425
call_identifier: H2020
grant_number: '665385'
name: International IST Doctoral Program
publication: Science
publication_identifier:
eissn:
- '10959203'
publication_status: published
publisher: American Association for the Advancement of Science
quality_controlled: '1'
scopus_import: '1'
status: public
title: The coupling mechanism of mammalian respiratory complex I
type: journal_article
user_id: 4359f0d1-fa6c-11eb-b949-802e58b17ae8
volume: 370
year: '2020'
...
---
_id: '8722'
abstract:
- lang: eng
text: "Load imbalance pervasively exists in distributed deep learning training systems,
either caused by the inherent imbalance in learned tasks or by the system itself.
Traditional synchronous Stochastic Gradient Descent (SGD)\r\nachieves good accuracy
for a wide variety of tasks, but relies on global synchronization to accumulate
the gradients at every training step. In this paper, we propose eager-SGD, which
relaxes the global synchronization for\r\ndecentralized accumulation. To implement
eager-SGD, we propose to use two partial collectives: solo and majority. With
solo allreduce, the faster processes contribute their gradients eagerly without
waiting for the slower processes, whereas with majority allreduce, at least half
of the participants must contribute gradients before continuing, all without using
a central parameter server. We theoretically prove the convergence of the algorithms
and describe the partial collectives in detail. Experimental results on load-imbalanced
environments (CIFAR-10, ImageNet, and UCF101 datasets) show\r\nthat eager-SGD
achieves 1.27x speedup over the state-of-the-art synchronous SGD, without losing
accuracy."
article_processing_charge: No
author:
- first_name: Shigang
full_name: Li, Shigang
last_name: Li
- first_name: Tal Ben-Nun
full_name: Tal Ben-Nun, Tal Ben-Nun
last_name: Tal Ben-Nun
- first_name: Salvatore Di
full_name: Girolamo, Salvatore Di
last_name: Girolamo
- first_name: Dan-Adrian
full_name: Alistarh, Dan-Adrian
id: 4A899BFC-F248-11E8-B48F-1D18A9856A87
last_name: Alistarh
orcid: 0000-0003-3650-940X
- first_name: Torsten
full_name: Hoefler, Torsten
last_name: Hoefler
citation:
ama: 'Li S, Tal Ben-Nun TB-N, Girolamo SD, Alistarh D-A, Hoefler T. Taming unbalanced
training workloads in deep learning with partial collective operations. In: Proceedings
of the 25th ACM SIGPLAN Symposium on Principles and Practice of Parallel Programming.
Association for Computing Machinery; 2020:45-61. doi:10.1145/3332466.3374528'
apa: 'Li, S., Tal Ben-Nun, T. B.-N., Girolamo, S. D., Alistarh, D.-A., & Hoefler,
T. (2020). Taming unbalanced training workloads in deep learning with partial
collective operations. In Proceedings of the 25th ACM SIGPLAN Symposium on
Principles and Practice of Parallel Programming (pp. 45–61). San Diego, CA,
United States: Association for Computing Machinery. https://doi.org/10.1145/3332466.3374528'
chicago: Li, Shigang, Tal Ben-Nun Tal Ben-Nun, Salvatore Di Girolamo, Dan-Adrian
Alistarh, and Torsten Hoefler. “Taming Unbalanced Training Workloads in Deep Learning
with Partial Collective Operations.” In Proceedings of the 25th ACM SIGPLAN
Symposium on Principles and Practice of Parallel Programming, 45–61. Association
for Computing Machinery, 2020. https://doi.org/10.1145/3332466.3374528.
ieee: S. Li, T. B.-N. Tal Ben-Nun, S. D. Girolamo, D.-A. Alistarh, and T. Hoefler,
“Taming unbalanced training workloads in deep learning with partial collective
operations,” in Proceedings of the 25th ACM SIGPLAN Symposium on Principles
and Practice of Parallel Programming, San Diego, CA, United States, 2020,
pp. 45–61.
ista: 'Li S, Tal Ben-Nun TB-N, Girolamo SD, Alistarh D-A, Hoefler T. 2020. Taming
unbalanced training workloads in deep learning with partial collective operations.
Proceedings of the 25th ACM SIGPLAN Symposium on Principles and Practice of Parallel
Programming. PPoPP: Sympopsium on Principles and Practice of Parallel Programming,
45–61.'
mla: Li, Shigang, et al. “Taming Unbalanced Training Workloads in Deep Learning
with Partial Collective Operations.” Proceedings of the 25th ACM SIGPLAN Symposium
on Principles and Practice of Parallel Programming, Association for Computing
Machinery, 2020, pp. 45–61, doi:10.1145/3332466.3374528.
short: S. Li, T.B.-N. Tal Ben-Nun, S.D. Girolamo, D.-A. Alistarh, T. Hoefler, in:,
Proceedings of the 25th ACM SIGPLAN Symposium on Principles and Practice of Parallel
Programming, Association for Computing Machinery, 2020, pp. 45–61.
conference:
end_date: 2020-02-26
location: San Diego, CA, United States
name: 'PPoPP: Sympopsium on Principles and Practice of Parallel Programming'
start_date: 2020-02-22
date_created: 2020-11-05T15:25:30Z
date_published: 2020-02-01T00:00:00Z
date_updated: 2023-08-22T12:13:48Z
day: '01'
department:
- _id: DaAl
doi: 10.1145/3332466.3374528
ec_funded: 1
external_id:
arxiv:
- '1908.04207'
isi:
- '000564476500004'
isi: 1
language:
- iso: eng
main_file_link:
- open_access: '1'
url: https://arxiv.org/abs/1908.04207
month: '02'
oa: 1
oa_version: Preprint
page: 45-61
project:
- _id: 268A44D6-B435-11E9-9278-68D0E5697425
call_identifier: H2020
grant_number: '805223'
name: Elastic Coordination for Scalable Machine Learning
publication: Proceedings of the 25th ACM SIGPLAN Symposium on Principles and Practice
of Parallel Programming
publication_status: published
publisher: Association for Computing Machinery
quality_controlled: '1'
status: public
title: Taming unbalanced training workloads in deep learning with partial collective
operations
type: conference
user_id: 4359f0d1-fa6c-11eb-b949-802e58b17ae8
year: '2020'
...
---
_id: '8744'
abstract:
- lang: eng
text: Understanding the conformational sampling of translation-arrested ribosome
nascent chain complexes is key to understand co-translational folding. Up to now,
coupling of cysteine oxidation, disulfide bond formation and structure formation
in nascent chains has remained elusive. Here, we investigate the eye-lens protein
γB-crystallin in the ribosomal exit tunnel. Using mass spectrometry, theoretical
simulations, dynamic nuclear polarization-enhanced solid-state nuclear magnetic
resonance and cryo-electron microscopy, we show that thiol groups of cysteine
residues undergo S-glutathionylation and S-nitrosylation and form non-native disulfide
bonds. Thus, covalent modification chemistry occurs already prior to nascent chain
release as the ribosome exit tunnel provides sufficient space even for disulfide
bond formation which can guide protein folding.
acknowledgement: 'We acknowledge help from Anja Seybert, Margot Frangakis, Diana Grewe,
Mikhail Eltsov, Utz Ermel, and Shintaro Aibara. The work was supported by Deutsche
Forschungsgemeinschaft in the CLiC graduate school. Work at the Center for Biomolecular
Magnetic Resonance (BMRZ) is supported by the German state of Hesse. The work at
BMRZ has been supported by the state of Hesse. L.S. has been supported by the DFG
graduate college: CLiC.'
article_number: '5569'
article_processing_charge: No
article_type: original
author:
- first_name: Linda
full_name: Schulte, Linda
last_name: Schulte
- first_name: Jiafei
full_name: Mao, Jiafei
last_name: Mao
- first_name: Julian
full_name: Reitz, Julian
last_name: Reitz
- first_name: Sridhar
full_name: Sreeramulu, Sridhar
last_name: Sreeramulu
- first_name: Denis
full_name: Kudlinzki, Denis
last_name: Kudlinzki
- first_name: Victor-Valentin
full_name: Hodirnau, Victor-Valentin
id: 3661B498-F248-11E8-B48F-1D18A9856A87
last_name: Hodirnau
- first_name: Jakob
full_name: Meier-Credo, Jakob
last_name: Meier-Credo
- first_name: Krishna
full_name: Saxena, Krishna
last_name: Saxena
- first_name: Florian
full_name: Buhr, Florian
last_name: Buhr
- first_name: Julian D.
full_name: Langer, Julian D.
last_name: Langer
- first_name: Martin
full_name: Blackledge, Martin
last_name: Blackledge
- first_name: Achilleas S.
full_name: Frangakis, Achilleas S.
last_name: Frangakis
- first_name: Clemens
full_name: Glaubitz, Clemens
last_name: Glaubitz
- first_name: Harald
full_name: Schwalbe, Harald
last_name: Schwalbe
citation:
ama: Schulte L, Mao J, Reitz J, et al. Cysteine oxidation and disulfide formation
in the ribosomal exit tunnel. Nature Communications. 2020;11. doi:10.1038/s41467-020-19372-x
apa: Schulte, L., Mao, J., Reitz, J., Sreeramulu, S., Kudlinzki, D., Hodirnau, V.-V.,
… Schwalbe, H. (2020). Cysteine oxidation and disulfide formation in the ribosomal
exit tunnel. Nature Communications. Springer Nature. https://doi.org/10.1038/s41467-020-19372-x
chicago: Schulte, Linda, Jiafei Mao, Julian Reitz, Sridhar Sreeramulu, Denis Kudlinzki,
Victor-Valentin Hodirnau, Jakob Meier-Credo, et al. “Cysteine Oxidation and Disulfide
Formation in the Ribosomal Exit Tunnel.” Nature Communications. Springer
Nature, 2020. https://doi.org/10.1038/s41467-020-19372-x.
ieee: L. Schulte et al., “Cysteine oxidation and disulfide formation in the
ribosomal exit tunnel,” Nature Communications, vol. 11. Springer Nature,
2020.
ista: Schulte L, Mao J, Reitz J, Sreeramulu S, Kudlinzki D, Hodirnau V-V, Meier-Credo
J, Saxena K, Buhr F, Langer JD, Blackledge M, Frangakis AS, Glaubitz C, Schwalbe
H. 2020. Cysteine oxidation and disulfide formation in the ribosomal exit tunnel.
Nature Communications. 11, 5569.
mla: Schulte, Linda, et al. “Cysteine Oxidation and Disulfide Formation in the Ribosomal
Exit Tunnel.” Nature Communications, vol. 11, 5569, Springer Nature, 2020,
doi:10.1038/s41467-020-19372-x.
short: L. Schulte, J. Mao, J. Reitz, S. Sreeramulu, D. Kudlinzki, V.-V. Hodirnau,
J. Meier-Credo, K. Saxena, F. Buhr, J.D. Langer, M. Blackledge, A.S. Frangakis,
C. Glaubitz, H. Schwalbe, Nature Communications 11 (2020).
date_created: 2020-11-09T07:49:36Z
date_published: 2020-11-04T00:00:00Z
date_updated: 2023-08-22T12:36:07Z
day: '04'
ddc:
- '570'
department:
- _id: EM-Fac
doi: 10.1038/s41467-020-19372-x
external_id:
isi:
- '000592028600001'
file:
- access_level: open_access
checksum: b2688f0347e69e6629bba582077278c5
content_type: application/pdf
creator: dernst
date_created: 2020-11-09T07:56:24Z
date_updated: 2020-11-09T07:56:24Z
file_id: '8745'
file_name: 2020_NatureComm_Schulte.pdf
file_size: 1670898
relation: main_file
success: 1
file_date_updated: 2020-11-09T07:56:24Z
has_accepted_license: '1'
intvolume: ' 11'
isi: 1
keyword:
- General Biochemistry
- Genetics and Molecular Biology
- General Physics and Astronomy
- General Chemistry
language:
- iso: eng
month: '11'
oa: 1
oa_version: Published Version
publication: Nature Communications
publication_identifier:
issn:
- 2041-1723
publication_status: published
publisher: Springer Nature
quality_controlled: '1'
scopus_import: '1'
status: public
title: Cysteine oxidation and disulfide formation in the ribosomal exit tunnel
tmp:
image: /images/cc_by.png
legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
short: CC BY (4.0)
type: journal_article
user_id: 4359f0d1-fa6c-11eb-b949-802e58b17ae8
volume: 11
year: '2020'
...
---
_id: '8747'
abstract:
- lang: eng
text: "Appropriately designed nanocomposites allow improving the thermoelectric
performance by several mechanisms, including phonon scattering, modulation doping
and energy filtering, while additionally promoting better mechanical properties
than those of crystalline materials. Here, a strategy for producing Bi2Te3–Cu2xTe
nanocomposites based on the consolidation of heterostructured nanoparticles is
described and the thermoelectric properties of the obtained materials are investigated.
We first detail a two-step solution-based process to produce Bi2Te3–Cu2xTe heteronanostructures,
based on the growth of Cu2xTe nanocrystals on the surface of Bi2Te3 nanowires.
We characterize the structural and chemical properties of the synthesized nanostructures
and of the nanocomposites\r\nproduced by hot-pressing the particles at moderate
temperatures. Besides, the transport properties of the nanocomposites are investigated
as a function of the amount of Cu introduced. Overall, the presence of Cu decreases
the material thermal conductivity through promotion of phonon scattering, modulates
the charge carrier concentration through electron spillover, and increases the
Seebeck coefficient through filtering of charge carriers at energy barriers. These
effects result in an improvement of over 50% of the thermoelectric figure of merit
of Bi2Te3."
acknowledgement: "This work was supported by the European Regional Development Funds
and by the Spanish Ministerio de Economı´a y\r\nCompetitividad through the project
SEHTOP (ENE2016-77798-C4-3-R). Y. Z. and X. H., thank the China Scholarship Council
for scholarship support. M. C. has received funding from the European Union’s Horizon
2020 Research and Innovation programme under the Marie Skłodowska-Curie Grant Agreement
No. 665385. M. I. acknowledges financial support from IST Austria. Y. L. acknowledges
funding from the European Union’s Horizon 2020 Research and Innovation Programme
under the Marie Sklodowska-Curie grant agreement no. 754411. ICN2 acknowledges funding
from Generalitat de Catalunya 2017 SGR 327 and the Spanish MINECO project ENE2017-85087-C3.
ICN2 is supported by the Severo Ochoa program from the Spanish MINECO (grant no.
SEV-2017-0706) and is funded by the CERCA Programme/Generalitat de Catalunya. Part
of the present work has been performed in the framework of Universitat \r\nAuto`noma
de Barcelona Materials Science PhD program."
article_processing_charge: No
article_type: original
author:
- first_name: Yu
full_name: Zhang, Yu
last_name: Zhang
- first_name: Yu
full_name: Liu, Yu
id: 2A70014E-F248-11E8-B48F-1D18A9856A87
last_name: Liu
orcid: 0000-0001-7313-6740
- first_name: Mariano
full_name: Calcabrini, Mariano
last_name: Calcabrini
- first_name: Congcong
full_name: Xing, Congcong
last_name: Xing
- first_name: Xu
full_name: Han, Xu
last_name: Han
- first_name: Jordi
full_name: Arbiol, Jordi
last_name: Arbiol
- first_name: Doris
full_name: Cadavid, Doris
last_name: Cadavid
- first_name: Maria
full_name: Ibáñez, Maria
id: 43C61214-F248-11E8-B48F-1D18A9856A87
last_name: Ibáñez
orcid: 0000-0001-5013-2843
- first_name: Andreu
full_name: Cabot, Andreu
last_name: Cabot
citation:
ama: Zhang Y, Liu Y, Calcabrini M, et al. Bismuth telluride-copper telluride nanocomposites
from heterostructured building blocks. Journal of Materials Chemistry C.
2020;8(40):14092-14099. doi:10.1039/D0TC02182B
apa: Zhang, Y., Liu, Y., Calcabrini, M., Xing, C., Han, X., Arbiol, J., … Cabot,
A. (2020). Bismuth telluride-copper telluride nanocomposites from heterostructured
building blocks. Journal of Materials Chemistry C. Royal Society of Chemistry.
https://doi.org/10.1039/D0TC02182B
chicago: Zhang, Yu, Yu Liu, Mariano Calcabrini, Congcong Xing, Xu Han, Jordi Arbiol,
Doris Cadavid, Maria Ibáñez, and Andreu Cabot. “Bismuth Telluride-Copper Telluride
Nanocomposites from Heterostructured Building Blocks.” Journal of Materials
Chemistry C. Royal Society of Chemistry, 2020. https://doi.org/10.1039/D0TC02182B.
ieee: Y. Zhang et al., “Bismuth telluride-copper telluride nanocomposites
from heterostructured building blocks,” Journal of Materials Chemistry C,
vol. 8, no. 40. Royal Society of Chemistry, pp. 14092–14099, 2020.
ista: Zhang Y, Liu Y, Calcabrini M, Xing C, Han X, Arbiol J, Cadavid D, Ibáñez M,
Cabot A. 2020. Bismuth telluride-copper telluride nanocomposites from heterostructured
building blocks. Journal of Materials Chemistry C. 8(40), 14092–14099.
mla: Zhang, Yu, et al. “Bismuth Telluride-Copper Telluride Nanocomposites from Heterostructured
Building Blocks.” Journal of Materials Chemistry C, vol. 8, no. 40, Royal
Society of Chemistry, 2020, pp. 14092–99, doi:10.1039/D0TC02182B.
short: Y. Zhang, Y. Liu, M. Calcabrini, C. Xing, X. Han, J. Arbiol, D. Cadavid,
M. Ibáñez, A. Cabot, Journal of Materials Chemistry C 8 (2020) 14092–14099.
date_created: 2020-11-09T08:37:51Z
date_published: 2020-10-28T00:00:00Z
date_updated: 2023-08-22T12:41:05Z
day: '28'
department:
- _id: MaIb
doi: 10.1039/D0TC02182B
ec_funded: 1
external_id:
isi:
- '000581559100015'
intvolume: ' 8'
isi: 1
issue: '40'
language:
- iso: eng
month: '10'
oa_version: None
page: 14092-14099
project:
- _id: 260C2330-B435-11E9-9278-68D0E5697425
call_identifier: H2020
grant_number: '754411'
name: ISTplus - Postdoctoral Fellowships
publication: Journal of Materials Chemistry C
publication_status: published
publisher: Royal Society of Chemistry
quality_controlled: '1'
scopus_import: '1'
status: public
title: Bismuth telluride-copper telluride nanocomposites from heterostructured building
blocks
type: journal_article
user_id: 4359f0d1-fa6c-11eb-b949-802e58b17ae8
volume: 8
year: '2020'
...
---
_id: '14095'
abstract:
- lang: eng
text: 'The Habitable Exoplanet Observatory, or HabEx, has been designed to be the
Great Observatory of the 2030s. For the first time in human history, technologies
have matured sufficiently to enable an affordable space-based telescope mission
capable of discovering and characterizing Earthlike planets orbiting nearby bright
sunlike stars in order to search for signs of habitability and biosignatures.
Such a mission can also be equipped with instrumentation that will enable broad
and exciting general astrophysics and planetary science not possible from current
or planned facilities. HabEx is a space telescope with unique imaging and multi-object
spectroscopic capabilities at wavelengths ranging from ultraviolet (UV) to near-IR.
These capabilities allow for a broad suite of compelling science that cuts across
the entire NASA astrophysics portfolio. HabEx has three primary science goals:
(1) Seek out nearby worlds and explore their habitability; (2) Map out nearby
planetary systems and understand the diversity of the worlds they contain; (3)
Enable new explorations of astrophysical systems from our own solar system to
external galaxies by extending our reach in the UV through near-IR. This Great
Observatory science will be selected through a competed GO program, and will account
for about 50% of the HabEx primary mission. The preferred HabEx architecture is
a 4m, monolithic, off-axis telescope that is diffraction-limited at 0.4 microns
and is in an L2 orbit. HabEx employs two starlight suppression systems: a coronagraph
and a starshade, each with their own dedicated instrument.'
article_number: '2001.06683'
article_processing_charge: No
author:
- first_name: B. Scott
full_name: Gaudi, B. Scott
last_name: Gaudi
- first_name: Sara
full_name: Seager, Sara
last_name: Seager
- first_name: Bertrand
full_name: Mennesson, Bertrand
last_name: Mennesson
- first_name: Alina
full_name: Kiessling, Alina
last_name: Kiessling
- first_name: Keith
full_name: Warfield, Keith
last_name: Warfield
- first_name: Kerri
full_name: Cahoy, Kerri
last_name: Cahoy
- first_name: John T.
full_name: Clarke, John T.
last_name: Clarke
- first_name: Shawn Domagal-Goldman
full_name: Shawn Domagal-Goldman, Shawn Domagal-Goldman
last_name: Shawn Domagal-Goldman
- first_name: Lee
full_name: Feinberg, Lee
last_name: Feinberg
- first_name: Olivier
full_name: Guyon, Olivier
last_name: Guyon
- first_name: Jeremy
full_name: Kasdin, Jeremy
last_name: Kasdin
- first_name: Dimitri
full_name: Mawet, Dimitri
last_name: Mawet
- first_name: Peter
full_name: Plavchan, Peter
last_name: Plavchan
- first_name: Tyler
full_name: Robinson, Tyler
last_name: Robinson
- first_name: Leslie
full_name: Rogers, Leslie
last_name: Rogers
- first_name: Paul
full_name: Scowen, Paul
last_name: Scowen
- first_name: Rachel
full_name: Somerville, Rachel
last_name: Somerville
- first_name: Karl
full_name: Stapelfeldt, Karl
last_name: Stapelfeldt
- first_name: Christopher
full_name: Stark, Christopher
last_name: Stark
- first_name: Daniel
full_name: Stern, Daniel
last_name: Stern
- first_name: Margaret
full_name: Turnbull, Margaret
last_name: Turnbull
- first_name: Rashied
full_name: Amini, Rashied
last_name: Amini
- first_name: Gary
full_name: Kuan, Gary
last_name: Kuan
- first_name: Stefan
full_name: Martin, Stefan
last_name: Martin
- first_name: Rhonda
full_name: Morgan, Rhonda
last_name: Morgan
- first_name: David
full_name: Redding, David
last_name: Redding
- first_name: H. Philip
full_name: Stahl, H. Philip
last_name: Stahl
- first_name: Ryan
full_name: Webb, Ryan
last_name: Webb
- first_name: Oscar Alvarez-Salazar
full_name: Oscar Alvarez-Salazar, Oscar Alvarez-Salazar
last_name: Oscar Alvarez-Salazar
- first_name: William L.
full_name: Arnold, William L.
last_name: Arnold
- first_name: Manan
full_name: Arya, Manan
last_name: Arya
- first_name: Bala
full_name: Balasubramanian, Bala
last_name: Balasubramanian
- first_name: Mike
full_name: Baysinger, Mike
last_name: Baysinger
- first_name: Ray
full_name: Bell, Ray
last_name: Bell
- first_name: Chris
full_name: Below, Chris
last_name: Below
- first_name: Jonathan
full_name: Benson, Jonathan
last_name: Benson
- first_name: Lindsey
full_name: Blais, Lindsey
last_name: Blais
- first_name: Jeff
full_name: Booth, Jeff
last_name: Booth
- first_name: Robert
full_name: Bourgeois, Robert
last_name: Bourgeois
- first_name: Case
full_name: Bradford, Case
last_name: Bradford
- first_name: Alden
full_name: Brewer, Alden
last_name: Brewer
- first_name: Thomas
full_name: Brooks, Thomas
last_name: Brooks
- first_name: Eric
full_name: Cady, Eric
last_name: Cady
- first_name: Mary
full_name: Caldwell, Mary
last_name: Caldwell
- first_name: Rob
full_name: Calvet, Rob
last_name: Calvet
- first_name: Steven
full_name: Carr, Steven
last_name: Carr
- first_name: Derek
full_name: Chan, Derek
last_name: Chan
- first_name: Velibor
full_name: Cormarkovic, Velibor
last_name: Cormarkovic
- first_name: Keith
full_name: Coste, Keith
last_name: Coste
- first_name: Charlie
full_name: Cox, Charlie
last_name: Cox
- first_name: Rolf
full_name: Danner, Rolf
last_name: Danner
- first_name: Jacqueline
full_name: Davis, Jacqueline
last_name: Davis
- first_name: Larry
full_name: Dewell, Larry
last_name: Dewell
- first_name: Lisa
full_name: Dorsett, Lisa
last_name: Dorsett
- first_name: Daniel
full_name: Dunn, Daniel
last_name: Dunn
- first_name: Matthew
full_name: East, Matthew
last_name: East
- first_name: Michael
full_name: Effinger, Michael
last_name: Effinger
- first_name: Ron
full_name: Eng, Ron
last_name: Eng
- first_name: Greg
full_name: Freebury, Greg
last_name: Freebury
- first_name: Jay
full_name: Garcia, Jay
last_name: Garcia
- first_name: Jonathan
full_name: Gaskin, Jonathan
last_name: Gaskin
- first_name: Suzan
full_name: Greene, Suzan
last_name: Greene
- first_name: John
full_name: Hennessy, John
last_name: Hennessy
- first_name: Evan
full_name: Hilgemann, Evan
last_name: Hilgemann
- first_name: Brad
full_name: Hood, Brad
last_name: Hood
- first_name: Wolfgang
full_name: Holota, Wolfgang
last_name: Holota
- first_name: Scott
full_name: Howe, Scott
last_name: Howe
- first_name: Pei
full_name: Huang, Pei
last_name: Huang
- first_name: Tony
full_name: Hull, Tony
last_name: Hull
- first_name: Ron
full_name: Hunt, Ron
last_name: Hunt
- first_name: Kevin
full_name: Hurd, Kevin
last_name: Hurd
- first_name: Sandra
full_name: Johnson, Sandra
last_name: Johnson
- first_name: Andrew
full_name: Kissil, Andrew
last_name: Kissil
- first_name: Brent
full_name: Knight, Brent
last_name: Knight
- first_name: Daniel
full_name: Kolenz, Daniel
last_name: Kolenz
- first_name: Oliver
full_name: Kraus, Oliver
last_name: Kraus
- first_name: John
full_name: Krist, John
last_name: Krist
- first_name: Mary
full_name: Li, Mary
last_name: Li
- first_name: Doug
full_name: Lisman, Doug
last_name: Lisman
- first_name: Milan
full_name: Mandic, Milan
last_name: Mandic
- first_name: John
full_name: Mann, John
last_name: Mann
- first_name: Luis
full_name: Marchen, Luis
last_name: Marchen
- first_name: Colleen Marrese-Reading
full_name: Colleen Marrese-Reading, Colleen Marrese-Reading
last_name: Colleen Marrese-Reading
- first_name: Jonathan
full_name: McCready, Jonathan
last_name: McCready
- first_name: Jim
full_name: McGown, Jim
last_name: McGown
- first_name: Jessica
full_name: Missun, Jessica
last_name: Missun
- first_name: Andrew
full_name: Miyaguchi, Andrew
last_name: Miyaguchi
- first_name: Bradley
full_name: Moore, Bradley
last_name: Moore
- first_name: Bijan
full_name: Nemati, Bijan
last_name: Nemati
- first_name: Shouleh
full_name: Nikzad, Shouleh
last_name: Nikzad
- first_name: Joel
full_name: Nissen, Joel
last_name: Nissen
- first_name: Megan
full_name: Novicki, Megan
last_name: Novicki
- first_name: Todd
full_name: Perrine, Todd
last_name: Perrine
- first_name: Claudia
full_name: Pineda, Claudia
last_name: Pineda
- first_name: Otto
full_name: Polanco, Otto
last_name: Polanco
- first_name: Dustin
full_name: Putnam, Dustin
last_name: Putnam
- first_name: Atif
full_name: Qureshi, Atif
last_name: Qureshi
- first_name: Michael
full_name: Richards, Michael
last_name: Richards
- first_name: A. J. Eldorado
full_name: Riggs, A. J. Eldorado
last_name: Riggs
- first_name: Michael
full_name: Rodgers, Michael
last_name: Rodgers
- first_name: Mike
full_name: Rud, Mike
last_name: Rud
- first_name: Navtej
full_name: Saini, Navtej
last_name: Saini
- first_name: Dan
full_name: Scalisi, Dan
last_name: Scalisi
- first_name: Dan
full_name: Scharf, Dan
last_name: Scharf
- first_name: Kevin
full_name: Schulz, Kevin
last_name: Schulz
- first_name: Gene
full_name: Serabyn, Gene
last_name: Serabyn
- first_name: Norbert
full_name: Sigrist, Norbert
last_name: Sigrist
- first_name: Glory
full_name: Sikkia, Glory
last_name: Sikkia
- first_name: Andrew
full_name: Singleton, Andrew
last_name: Singleton
- first_name: Stuart
full_name: Shaklan, Stuart
last_name: Shaklan
- first_name: Scott
full_name: Smith, Scott
last_name: Smith
- first_name: Bart
full_name: Southerd, Bart
last_name: Southerd
- first_name: Mark
full_name: Stahl, Mark
last_name: Stahl
- first_name: John
full_name: Steeves, John
last_name: Steeves
- first_name: Brian
full_name: Sturges, Brian
last_name: Sturges
- first_name: Chris
full_name: Sullivan, Chris
last_name: Sullivan
- first_name: Hao
full_name: Tang, Hao
last_name: Tang
- first_name: Neil
full_name: Taras, Neil
last_name: Taras
- first_name: Jonathan
full_name: Tesch, Jonathan
last_name: Tesch
- first_name: Melissa
full_name: Therrell, Melissa
last_name: Therrell
- first_name: Howard
full_name: Tseng, Howard
last_name: Tseng
- first_name: Marty
full_name: Valente, Marty
last_name: Valente
- first_name: David Van
full_name: Buren, David Van
last_name: Buren
- first_name: Juan
full_name: Villalvazo, Juan
last_name: Villalvazo
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full_name: Warwick, Steve
last_name: Warwick
- first_name: David
full_name: Webb, David
last_name: Webb
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full_name: Westerhoff, Thomas
last_name: Westerhoff
- first_name: Rush
full_name: Wofford, Rush
last_name: Wofford
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full_name: Wu, Gordon
last_name: Wu
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full_name: Woo, Jahning
last_name: Woo
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full_name: Wood, Milana
last_name: Wood
- first_name: John
full_name: Ziemer, John
last_name: Ziemer
- first_name: Giada
full_name: Arney, Giada
last_name: Arney
- first_name: Jay
full_name: Anderson, Jay
last_name: Anderson
- first_name: Jesús Maíz-Apellániz
full_name: Jesús Maíz-Apellániz, Jesús Maíz-Apellániz
last_name: Jesús Maíz-Apellániz
- first_name: James
full_name: Bartlett, James
last_name: Bartlett
- first_name: Ruslan
full_name: Belikov, Ruslan
last_name: Belikov
- first_name: Eduardo
full_name: Bendek, Eduardo
last_name: Bendek
- first_name: Brad
full_name: Cenko, Brad
last_name: Cenko
- first_name: Ewan
full_name: Douglas, Ewan
last_name: Douglas
- first_name: Shannon
full_name: Dulz, Shannon
last_name: Dulz
- first_name: Chris
full_name: Evans, Chris
last_name: Evans
- first_name: Virginie
full_name: Faramaz, Virginie
last_name: Faramaz
- first_name: Y. Katherina
full_name: Feng, Y. Katherina
last_name: Feng
- first_name: Harry
full_name: Ferguson, Harry
last_name: Ferguson
- first_name: Kate
full_name: Follette, Kate
last_name: Follette
- first_name: Saavik
full_name: Ford, Saavik
last_name: Ford
- first_name: Miriam
full_name: García, Miriam
last_name: García
- first_name: Marla
full_name: Geha, Marla
last_name: Geha
- first_name: Dawn
full_name: Gelino, Dawn
last_name: Gelino
- first_name: Ylva Louise Linsdotter
full_name: Götberg, Ylva Louise Linsdotter
id: d0648d0c-0f64-11ee-a2e0-dd0faa2e4f7d
last_name: Götberg
orcid: 0000-0002-6960-6911
- first_name: Sergi
full_name: Hildebrandt, Sergi
last_name: Hildebrandt
- first_name: Renyu
full_name: Hu, Renyu
last_name: Hu
- first_name: Knud
full_name: Jahnke, Knud
last_name: Jahnke
- first_name: Grant
full_name: Kennedy, Grant
last_name: Kennedy
- first_name: Laura
full_name: Kreidberg, Laura
last_name: Kreidberg
- first_name: Andrea
full_name: Isella, Andrea
last_name: Isella
- first_name: Eric
full_name: Lopez, Eric
last_name: Lopez
- first_name: Franck
full_name: Marchis, Franck
last_name: Marchis
- first_name: Lucas
full_name: Macri, Lucas
last_name: Macri
- first_name: Mark
full_name: Marley, Mark
last_name: Marley
- first_name: William
full_name: Matzko, William
last_name: Matzko
- first_name: Johan
full_name: Mazoyer, Johan
last_name: Mazoyer
- first_name: Stephan
full_name: McCandliss, Stephan
last_name: McCandliss
- first_name: Tiffany
full_name: Meshkat, Tiffany
last_name: Meshkat
- first_name: Christoph
full_name: Mordasini, Christoph
last_name: Mordasini
- first_name: Patrick
full_name: Morris, Patrick
last_name: Morris
- first_name: Eric
full_name: Nielsen, Eric
last_name: Nielsen
- first_name: Patrick
full_name: Newman, Patrick
last_name: Newman
- first_name: Erik
full_name: Petigura, Erik
last_name: Petigura
- first_name: Marc
full_name: Postman, Marc
last_name: Postman
- first_name: Amy
full_name: Reines, Amy
last_name: Reines
- first_name: Aki
full_name: Roberge, Aki
last_name: Roberge
- first_name: Ian
full_name: Roederer, Ian
last_name: Roederer
- first_name: Garreth
full_name: Ruane, Garreth
last_name: Ruane
- first_name: Edouard
full_name: Schwieterman, Edouard
last_name: Schwieterman
- first_name: Dan
full_name: Sirbu, Dan
last_name: Sirbu
- first_name: Christopher
full_name: Spalding, Christopher
last_name: Spalding
- first_name: Harry
full_name: Teplitz, Harry
last_name: Teplitz
- first_name: Jason
full_name: Tumlinson, Jason
last_name: Tumlinson
- first_name: Neal
full_name: Turner, Neal
last_name: Turner
- first_name: Jessica
full_name: Werk, Jessica
last_name: Werk
- first_name: Aida
full_name: Wofford, Aida
last_name: Wofford
- first_name: Mark
full_name: Wyatt, Mark
last_name: Wyatt
- first_name: Amber
full_name: Young, Amber
last_name: Young
- first_name: Rob
full_name: Zellem, Rob
last_name: Zellem
citation:
ama: Gaudi BS, Seager S, Mennesson B, et al. The habitable exoplanet observatory
(HabEx) mission concept study final report. arXiv. doi:10.48550/arXiv.2001.06683
apa: Gaudi, B. S., Seager, S., Mennesson, B., Kiessling, A., Warfield, K., Cahoy,
K., … Zellem, R. (n.d.). The habitable exoplanet observatory (HabEx) mission concept
study final report. arXiv. https://doi.org/10.48550/arXiv.2001.06683
chicago: Gaudi, B. Scott, Sara Seager, Bertrand Mennesson, Alina Kiessling, Keith
Warfield, Kerri Cahoy, John T. Clarke, et al. “The Habitable Exoplanet Observatory
(HabEx) Mission Concept Study Final Report.” ArXiv, n.d. https://doi.org/10.48550/arXiv.2001.06683.
ieee: B. S. Gaudi et al., “The habitable exoplanet observatory (HabEx) mission
concept study final report,” arXiv. .
ista: Gaudi BS et al. The habitable exoplanet observatory (HabEx) mission concept
study final report. arXiv, 2001.06683.
mla: Gaudi, B. Scott, et al. “The Habitable Exoplanet Observatory (HabEx) Mission
Concept Study Final Report.” ArXiv, 2001.06683, doi:10.48550/arXiv.2001.06683.
short: B.S. Gaudi, S. Seager, B. Mennesson, A. Kiessling, K. Warfield, K. Cahoy,
J.T. Clarke, S.D.-G. Shawn Domagal-Goldman, L. Feinberg, O. Guyon, J. Kasdin,
D. Mawet, P. Plavchan, T. Robinson, L. Rogers, P. Scowen, R. Somerville, K. Stapelfeldt,
C. Stark, D. Stern, M. Turnbull, R. Amini, G. Kuan, S. Martin, R. Morgan, D. Redding,
H.P. Stahl, R. Webb, O.A.-S. Oscar Alvarez-Salazar, W.L. Arnold, M. Arya, B. Balasubramanian,
M. Baysinger, R. Bell, C. Below, J. Benson, L. Blais, J. Booth, R. Bourgeois,
C. Bradford, A. Brewer, T. Brooks, E. Cady, M. Caldwell, R. Calvet, S. Carr, D.
Chan, V. Cormarkovic, K. Coste, C. Cox, R. Danner, J. Davis, L. Dewell, L. Dorsett,
D. Dunn, M. East, M. Effinger, R. Eng, G. Freebury, J. Garcia, J. Gaskin, S. Greene,
J. Hennessy, E. Hilgemann, B. Hood, W. Holota, S. Howe, P. Huang, T. Hull, R.
Hunt, K. Hurd, S. Johnson, A. Kissil, B. Knight, D. Kolenz, O. Kraus, J. Krist,
M. Li, D. Lisman, M. Mandic, J. Mann, L. Marchen, C.M.-R. Colleen Marrese-Reading,
J. McCready, J. McGown, J. Missun, A. Miyaguchi, B. Moore, B. Nemati, S. Nikzad,
J. Nissen, M. Novicki, T. Perrine, C. Pineda, O. Polanco, D. Putnam, A. Qureshi,
M. Richards, A.J.E. Riggs, M. Rodgers, M. Rud, N. Saini, D. Scalisi, D. Scharf,
K. Schulz, G. Serabyn, N. Sigrist, G. Sikkia, A. Singleton, S. Shaklan, S. Smith,
B. Southerd, M. Stahl, J. Steeves, B. Sturges, C. Sullivan, H. Tang, N. Taras,
J. Tesch, M. Therrell, H. Tseng, M. Valente, D.V. Buren, J. Villalvazo, S. Warwick,
D. Webb, T. Westerhoff, R. Wofford, G. Wu, J. Woo, M. Wood, J. Ziemer, G. Arney,
J. Anderson, J.M.-A. Jesús Maíz-Apellániz, J. Bartlett, R. Belikov, E. Bendek,
B. Cenko, E. Douglas, S. Dulz, C. Evans, V. Faramaz, Y.K. Feng, H. Ferguson, K.
Follette, S. Ford, M. García, M. Geha, D. Gelino, Y.L.L. Götberg, S. Hildebrandt,
R. Hu, K. Jahnke, G. Kennedy, L. Kreidberg, A. Isella, E. Lopez, F. Marchis, L.
Macri, M. Marley, W. Matzko, J. Mazoyer, S. McCandliss, T. Meshkat, C. Mordasini,
P. Morris, E. Nielsen, P. Newman, E. Petigura, M. Postman, A. Reines, A. Roberge,
I. Roederer, G. Ruane, E. Schwieterman, D. Sirbu, C. Spalding, H. Teplitz, J.
Tumlinson, N. Turner, J. Werk, A. Wofford, M. Wyatt, A. Young, R. Zellem, ArXiv
(n.d.).
date_created: 2023-08-21T10:10:21Z
date_published: 2020-01-18T00:00:00Z
date_updated: 2023-08-22T13:13:18Z
day: '18'
doi: 10.48550/arXiv.2001.06683
extern: '1'
external_id:
arxiv:
- '2001.06683'
language:
- iso: eng
main_file_link:
- open_access: '1'
url: ' https://doi.org/10.48550/arXiv.2001.06683'
month: '01'
oa: 1
oa_version: Preprint
publication: arXiv
publication_status: submitted
status: public
title: The habitable exoplanet observatory (HabEx) mission concept study final report
type: preprint
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
year: '2020'
...
---
_id: '8767'
abstract:
- lang: eng
text: Resources are rarely distributed uniformly within a population. Heterogeneity
in the concentration of a drug, the quality of breeding sites, or wealth can all
affect evolutionary dynamics. In this study, we represent a collection of properties
affecting the fitness at a given location using a color. A green node is rich
in resources while a red node is poorer. More colors can represent a broader spectrum
of resource qualities. For a population evolving according to the birth-death
Moran model, the first question we address is which structures, identified by
graph connectivity and graph coloring, are evolutionarily equivalent. We prove
that all properly two-colored, undirected, regular graphs are evolutionarily equivalent
(where “properly colored” means that no two neighbors have the same color). We
then compare the effects of background heterogeneity on properly two-colored graphs
to those with alternative schemes in which the colors are permuted. Finally, we
discuss dynamic coloring as a model for spatiotemporal resource fluctuations,
and we illustrate that random dynamic colorings often diminish the effects of
background heterogeneity relative to a proper two-coloring.
acknowledgement: 'We thank Igor Erovenko for many helpful comments on an earlier version
of this paper. : Army Research Laboratory (grant W911NF-18-2-0265) (M.A.N.); the
Bill & Melinda Gates Foundation (grant OPP1148627) (M.A.N.); the NVIDIA Corporation
(A.M.). The funders had no role in study design, data collection and analysis, decision
to publish, or preparation of the manuscript.'
article_number: e1008402
article_processing_charge: No
article_type: original
author:
- first_name: Kamran
full_name: Kaveh, Kamran
last_name: Kaveh
- first_name: Alex
full_name: McAvoy, Alex
last_name: McAvoy
- first_name: Krishnendu
full_name: Chatterjee, Krishnendu
id: 2E5DCA20-F248-11E8-B48F-1D18A9856A87
last_name: Chatterjee
orcid: 0000-0002-4561-241X
- first_name: Martin A.
full_name: Nowak, Martin A.
last_name: Nowak
citation:
ama: Kaveh K, McAvoy A, Chatterjee K, Nowak MA. The Moran process on 2-chromatic
graphs. PLOS Computational Biology. 2020;16(11). doi:10.1371/journal.pcbi.1008402
apa: Kaveh, K., McAvoy, A., Chatterjee, K., & Nowak, M. A. (2020). The Moran
process on 2-chromatic graphs. PLOS Computational Biology. Public Library
of Science. https://doi.org/10.1371/journal.pcbi.1008402
chicago: Kaveh, Kamran, Alex McAvoy, Krishnendu Chatterjee, and Martin A. Nowak.
“The Moran Process on 2-Chromatic Graphs.” PLOS Computational Biology.
Public Library of Science, 2020. https://doi.org/10.1371/journal.pcbi.1008402.
ieee: K. Kaveh, A. McAvoy, K. Chatterjee, and M. A. Nowak, “The Moran process on
2-chromatic graphs,” PLOS Computational Biology, vol. 16, no. 11. Public
Library of Science, 2020.
ista: Kaveh K, McAvoy A, Chatterjee K, Nowak MA. 2020. The Moran process on 2-chromatic
graphs. PLOS Computational Biology. 16(11), e1008402.
mla: Kaveh, Kamran, et al. “The Moran Process on 2-Chromatic Graphs.” PLOS Computational
Biology, vol. 16, no. 11, e1008402, Public Library of Science, 2020, doi:10.1371/journal.pcbi.1008402.
short: K. Kaveh, A. McAvoy, K. Chatterjee, M.A. Nowak, PLOS Computational Biology
16 (2020).
date_created: 2020-11-18T07:20:23Z
date_published: 2020-11-05T00:00:00Z
date_updated: 2023-08-22T12:49:18Z
day: '05'
ddc:
- '000'
department:
- _id: KrCh
doi: 10.1371/journal.pcbi.1008402
external_id:
isi:
- '000591317200004'
file:
- access_level: open_access
checksum: 555456dd0e47bcf9e0994bcb95577e88
content_type: application/pdf
creator: dernst
date_created: 2020-11-18T07:26:10Z
date_updated: 2020-11-18T07:26:10Z
file_id: '8768'
file_name: 2020_PlosCompBio_Kaveh.pdf
file_size: 2498594
relation: main_file
success: 1
file_date_updated: 2020-11-18T07:26:10Z
has_accepted_license: '1'
intvolume: ' 16'
isi: 1
issue: '11'
keyword:
- Ecology
- Modelling and Simulation
- Computational Theory and Mathematics
- Genetics
- Ecology
- Evolution
- Behavior and Systematics
- Molecular Biology
- Cellular and Molecular Neuroscience
language:
- iso: eng
month: '11'
oa: 1
oa_version: Published Version
publication: PLOS Computational Biology
publication_identifier:
eissn:
- 1553-7358
issn:
- 1553-734X
publication_status: published
publisher: Public Library of Science
quality_controlled: '1'
scopus_import: '1'
status: public
title: The Moran process on 2-chromatic graphs
tmp:
image: /images/cc_by.png
legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
short: CC BY (4.0)
type: journal_article
user_id: 4359f0d1-fa6c-11eb-b949-802e58b17ae8
volume: 16
year: '2020'
...
---
_id: '8750'
abstract:
- lang: eng
text: "Efficiently handling time-triggered and possibly nondeterministic switches\r\nfor
hybrid systems reachability is a challenging task. In this paper we present\r\nan
approach based on conservative set-based enclosure of the dynamics that can\r\nhandle
systems with uncertain parameters and inputs, where the uncertainties\r\nare bound
to given intervals. The method is evaluated on the plant model of an\r\nexperimental
electro-mechanical braking system with periodic controller. In\r\nthis model,
the fast-switching controller dynamics requires simulation time\r\nscales of the
order of nanoseconds. Accurate set-based computations for\r\nrelatively large
time horizons are known to be expensive. However, by\r\nappropriately decoupling
the time variable with respect to the spatial\r\nvariables, and enclosing the
uncertain parameters using interval matrix maps\r\nacting on zonotopes, we show
that the computation time can be lowered to 5000\r\ntimes faster with respect
to previous works. This is a step forward in formal\r\nverification of hybrid
systems because reduced run-times allow engineers to\r\nintroduce more expressiveness
in their models with a relatively inexpensive\r\ncomputational cost."
article_number: '9314994'
article_processing_charge: No
author:
- first_name: Marcelo
full_name: Forets, Marcelo
last_name: Forets
- first_name: Daniel
full_name: Freire, Daniel
last_name: Freire
- first_name: Christian
full_name: Schilling, Christian
id: 3A2F4DCE-F248-11E8-B48F-1D18A9856A87
last_name: Schilling
orcid: 0000-0003-3658-1065
citation:
ama: 'Forets M, Freire D, Schilling C. Efficient reachability analysis of parametric
linear hybrid systems with time-triggered transitions. In: 18th ACM-IEEE International
Conference on Formal Methods and Models for System Design. IEEE; 2020. doi:10.1109/MEMOCODE51338.2020.9314994'
apa: 'Forets, M., Freire, D., & Schilling, C. (2020). Efficient reachability
analysis of parametric linear hybrid systems with time-triggered transitions.
In 18th ACM-IEEE International Conference on Formal Methods and Models for
System Design. Virtual Conference: IEEE. https://doi.org/10.1109/MEMOCODE51338.2020.9314994'
chicago: Forets, Marcelo, Daniel Freire, and Christian Schilling. “Efficient Reachability
Analysis of Parametric Linear Hybrid Systems with Time-Triggered Transitions.”
In 18th ACM-IEEE International Conference on Formal Methods and Models for
System Design. IEEE, 2020. https://doi.org/10.1109/MEMOCODE51338.2020.9314994.
ieee: M. Forets, D. Freire, and C. Schilling, “Efficient reachability analysis of
parametric linear hybrid systems with time-triggered transitions,” in 18th
ACM-IEEE International Conference on Formal Methods and Models for System Design,
Virtual Conference, 2020.
ista: 'Forets M, Freire D, Schilling C. 2020. Efficient reachability analysis of
parametric linear hybrid systems with time-triggered transitions. 18th ACM-IEEE
International Conference on Formal Methods and Models for System Design. MEMOCODE:
Conference on Formal Methods and Models for System Design, 9314994.'
mla: Forets, Marcelo, et al. “Efficient Reachability Analysis of Parametric Linear
Hybrid Systems with Time-Triggered Transitions.” 18th ACM-IEEE International
Conference on Formal Methods and Models for System Design, 9314994, IEEE,
2020, doi:10.1109/MEMOCODE51338.2020.9314994.
short: M. Forets, D. Freire, C. Schilling, in:, 18th ACM-IEEE International Conference
on Formal Methods and Models for System Design, IEEE, 2020.
conference:
end_date: 2020-12-04
location: Virtual Conference
name: 'MEMOCODE: Conference on Formal Methods and Models for System Design'
start_date: 2020-12-02
date_created: 2020-11-10T07:04:57Z
date_published: 2020-12-04T00:00:00Z
date_updated: 2023-08-22T12:48:18Z
day: '04'
department:
- _id: ToHe
doi: 10.1109/MEMOCODE51338.2020.9314994
ec_funded: 1
external_id:
arxiv:
- '2006.12325'
isi:
- '000661920400013'
isi: 1
language:
- iso: eng
main_file_link:
- open_access: '1'
url: https://arxiv.org/abs/2006.12325
month: '12'
oa: 1
oa_version: Preprint
project:
- _id: 25F42A32-B435-11E9-9278-68D0E5697425
call_identifier: FWF
grant_number: Z211
name: The Wittgenstein Prize
- _id: 260C2330-B435-11E9-9278-68D0E5697425
call_identifier: H2020
grant_number: '754411'
name: ISTplus - Postdoctoral Fellowships
publication: 18th ACM-IEEE International Conference on Formal Methods and Models for
System Design
publication_identifier:
isbn:
- '9781728191485'
publication_status: published
publisher: IEEE
quality_controlled: '1'
scopus_import: '1'
status: public
title: Efficient reachability analysis of parametric linear hybrid systems with time-triggered
transitions
type: conference
user_id: 4359f0d1-fa6c-11eb-b949-802e58b17ae8
year: '2020'
...
---
_id: '8758'
abstract:
- lang: eng
text: We consider various modeling levels for spatially homogeneous chemical reaction
systems, namely the chemical master equation, the chemical Langevin dynamics,
and the reaction-rate equation. Throughout we restrict our study to the case where
the microscopic system satisfies the detailed-balance condition. The latter allows
us to enrich the systems with a gradient structure, i.e. the evolution is given
by a gradient-flow equation. We present the arising links between the associated
gradient structures that are driven by the relative entropy of the detailed-balance
steady state. The limit of large volumes is studied in the sense of evolutionary
Γ-convergence of gradient flows. Moreover, we use the gradient structures to derive
hybrid models for coupling different modeling levels.
acknowledgement: The research of A.M. was partially supported by the Deutsche Forschungsgemeinschaft
(DFG) via the Collaborative Research Center SFB 1114 Scaling Cascades in Complex
Systems (Project No. 235221301), through the Subproject C05 Effective models for
materials and interfaces with multiple scales. J.M. gratefully acknowledges support
by the European Research Council (ERC) under the European Union’s Horizon 2020 research
and innovation programme (Grant Agreement No. 716117), and by the Austrian Science
Fund (FWF), Project SFB F65. The authors thank Christof Schütte, Robert I. A. Patterson,
and Stefanie Winkelmann for helpful and stimulating discussions. Open access funding
provided by Austrian Science Fund (FWF).
article_processing_charge: No
article_type: original
author:
- first_name: Jan
full_name: Maas, Jan
id: 4C5696CE-F248-11E8-B48F-1D18A9856A87
last_name: Maas
orcid: 0000-0002-0845-1338
- first_name: Alexander
full_name: Mielke, Alexander
last_name: Mielke
citation:
ama: Maas J, Mielke A. Modeling of chemical reaction systems with detailed balance
using gradient structures. Journal of Statistical Physics. 2020;181(6):2257-2303.
doi:10.1007/s10955-020-02663-4
apa: Maas, J., & Mielke, A. (2020). Modeling of chemical reaction systems with
detailed balance using gradient structures. Journal of Statistical Physics.
Springer Nature. https://doi.org/10.1007/s10955-020-02663-4
chicago: Maas, Jan, and Alexander Mielke. “Modeling of Chemical Reaction Systems
with Detailed Balance Using Gradient Structures.” Journal of Statistical Physics.
Springer Nature, 2020. https://doi.org/10.1007/s10955-020-02663-4.
ieee: J. Maas and A. Mielke, “Modeling of chemical reaction systems with detailed
balance using gradient structures,” Journal of Statistical Physics, vol.
181, no. 6. Springer Nature, pp. 2257–2303, 2020.
ista: Maas J, Mielke A. 2020. Modeling of chemical reaction systems with detailed
balance using gradient structures. Journal of Statistical Physics. 181(6), 2257–2303.
mla: Maas, Jan, and Alexander Mielke. “Modeling of Chemical Reaction Systems with
Detailed Balance Using Gradient Structures.” Journal of Statistical Physics,
vol. 181, no. 6, Springer Nature, 2020, pp. 2257–303, doi:10.1007/s10955-020-02663-4.
short: J. Maas, A. Mielke, Journal of Statistical Physics 181 (2020) 2257–2303.
date_created: 2020-11-15T23:01:18Z
date_published: 2020-12-01T00:00:00Z
date_updated: 2023-08-22T13:24:27Z
day: '01'
ddc:
- '510'
department:
- _id: JaMa
doi: 10.1007/s10955-020-02663-4
ec_funded: 1
external_id:
arxiv:
- '2004.02831'
isi:
- '000587107200002'
file:
- access_level: open_access
checksum: bc2b63a90197b97cbc73eccada4639f5
content_type: application/pdf
creator: dernst
date_created: 2021-02-04T10:29:11Z
date_updated: 2021-02-04T10:29:11Z
file_id: '9087'
file_name: 2020_JourStatPhysics_Maas.pdf
file_size: 753596
relation: main_file
success: 1
file_date_updated: 2021-02-04T10:29:11Z
has_accepted_license: '1'
intvolume: ' 181'
isi: 1
issue: '6'
language:
- iso: eng
month: '12'
oa: 1
oa_version: Published Version
page: 2257-2303
project:
- _id: 256E75B8-B435-11E9-9278-68D0E5697425
call_identifier: H2020
grant_number: '716117'
name: Optimal Transport and Stochastic Dynamics
- _id: 260482E2-B435-11E9-9278-68D0E5697425
call_identifier: FWF
grant_number: ' F06504'
name: Taming Complexity in Partial Di erential Systems
publication: Journal of Statistical Physics
publication_identifier:
eissn:
- '15729613'
issn:
- '00224715'
publication_status: published
publisher: Springer Nature
quality_controlled: '1'
scopus_import: '1'
status: public
title: Modeling of chemical reaction systems with detailed balance using gradient
structures
tmp:
image: /images/cc_by.png
legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
short: CC BY (4.0)
type: journal_article
user_id: 4359f0d1-fa6c-11eb-b949-802e58b17ae8
volume: 181
year: '2020'
...
---
_id: '13070'
abstract:
- lang: eng
text: This dataset comprises all data shown in the figures of the submitted article
"Surpassing the resistance quantum with a geometric superinductor". Additional
raw data are available from the corresponding author on reasonable request.
article_processing_charge: No
author:
- first_name: Matilda
full_name: Peruzzo, Matilda
id: 3F920B30-F248-11E8-B48F-1D18A9856A87
last_name: Peruzzo
orcid: 0000-0002-3415-4628
- first_name: Andrea
full_name: Trioni, Andrea
id: 42F71B44-F248-11E8-B48F-1D18A9856A87
last_name: Trioni
- first_name: Farid
full_name: Hassani, Farid
id: 2AED110C-F248-11E8-B48F-1D18A9856A87
last_name: Hassani
orcid: 0000-0001-6937-5773
- first_name: Martin
full_name: Zemlicka, Martin
id: 2DCF8DE6-F248-11E8-B48F-1D18A9856A87
last_name: Zemlicka
- first_name: Johannes M
full_name: Fink, Johannes M
id: 4B591CBA-F248-11E8-B48F-1D18A9856A87
last_name: Fink
orcid: 0000-0001-8112-028X
citation:
ama: Peruzzo M, Trioni A, Hassani F, Zemlicka M, Fink JM. Surpassing the resistance
quantum with a geometric superinductor. 2020. doi:10.5281/ZENODO.4052882
apa: Peruzzo, M., Trioni, A., Hassani, F., Zemlicka, M., & Fink, J. M. (2020).
Surpassing the resistance quantum with a geometric superinductor. Zenodo. https://doi.org/10.5281/ZENODO.4052882
chicago: Peruzzo, Matilda, Andrea Trioni, Farid Hassani, Martin Zemlicka, and Johannes
M Fink. “Surpassing the Resistance Quantum with a Geometric Superinductor.” Zenodo,
2020. https://doi.org/10.5281/ZENODO.4052882.
ieee: M. Peruzzo, A. Trioni, F. Hassani, M. Zemlicka, and J. M. Fink, “Surpassing
the resistance quantum with a geometric superinductor.” Zenodo, 2020.
ista: Peruzzo M, Trioni A, Hassani F, Zemlicka M, Fink JM. 2020. Surpassing the
resistance quantum with a geometric superinductor, Zenodo, 10.5281/ZENODO.4052882.
mla: Peruzzo, Matilda, et al. Surpassing the Resistance Quantum with a Geometric
Superinductor. Zenodo, 2020, doi:10.5281/ZENODO.4052882.
short: M. Peruzzo, A. Trioni, F. Hassani, M. Zemlicka, J.M. Fink, (2020).
date_created: 2023-05-23T16:42:30Z
date_published: 2020-09-27T00:00:00Z
date_updated: 2023-08-22T13:23:57Z
day: '27'
ddc:
- '530'
department:
- _id: JoFi
doi: 10.5281/ZENODO.4052882
main_file_link:
- open_access: '1'
url: https://doi.org/10.5281/zenodo.4052883
month: '09'
oa: 1
oa_version: Published Version
publisher: Zenodo
related_material:
record:
- id: '8755'
relation: used_in_publication
status: public
status: public
title: Surpassing the resistance quantum with a geometric superinductor
tmp:
image: /images/cc_by.png
legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
short: CC BY (4.0)
type: research_data_reference
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
year: '2020'
...
---
_id: '8787'
abstract:
- lang: eng
text: Breakdown of vascular barriers is a major complication of inflammatory diseases.
Anucleate platelets form blood-clots during thrombosis, but also play a crucial
role in inflammation. While spatio-temporal dynamics of clot formation are well
characterized, the cell-biological mechanisms of platelet recruitment to inflammatory
micro-environments remain incompletely understood. Here we identify Arp2/3-dependent
lamellipodia formation as a prominent morphological feature of immune-responsive
platelets. Platelets use lamellipodia to scan for fibrin(ogen) deposited on the
inflamed vasculature and to directionally spread, to polarize and to govern haptotactic
migration along gradients of the adhesive ligand. Platelet-specific abrogation
of Arp2/3 interferes with haptotactic repositioning of platelets to microlesions,
thus impairing vascular sealing and provoking inflammatory microbleeding. During
infection, haptotaxis promotes capture of bacteria and prevents hematogenic dissemination,
rendering platelets gate-keepers of the inflamed microvasculature. Consequently,
these findings identify haptotaxis as a key effector function of immune-responsive
platelets.
acknowledgement: "We thank Sebastian Helmer, Nicole Blount, Christine Mann, and Beate
Jantz for technical assistance; Hellen Ishikawa-Ankerhold for help and advice; Michael
Sixt for critical\r\ndiscussions. This study was supported by the DFG SFB 914 (S.M.
[B02 and Z01], K.Sch.\r\n[B02], B.W. [A02 and Z03], C.A.R. [B03], C.S. [A10], J.P.
[Gerok position]), the DFG\r\nSFB 1123 (S.M. [B06]), the DFG FOR 2033 (S.M. and
F.G.), the German Center for\r\nCardiovascular Research (DZHK) (Clinician Scientist
Program [L.N.], MHA 1.4VD\r\n[S.M.], Postdoc Start-up Grant, 81×3600213 [F.G.]),
FP7 program (project 260309,\r\nPRESTIGE [S.M.]), FöFoLe project 1015/1009 (L.N.),
FöFoLe project 947 (F.G.), the\r\nFriedrich-Baur-Stiftung project 41/16 (F.G.),
and LMUexcellence NFF (F.G.). This project has received funding from the European
Research Council (ERC) under the European Union’s Horizon 2020 research and innovation
program (grant agreement no.\r\n833440) (S.M.). F.G. received funding from the European
Union’s Horizon 2020 research\r\nand innovation program under the Marie Skłodowska-Curie
grant agreement no.\r\n747687."
article_number: '5778'
article_processing_charge: No
article_type: original
author:
- first_name: Leo
full_name: Nicolai, Leo
last_name: Nicolai
- first_name: Karin
full_name: Schiefelbein, Karin
last_name: Schiefelbein
- first_name: Silvia
full_name: Lipsky, Silvia
last_name: Lipsky
- first_name: Alexander
full_name: Leunig, Alexander
last_name: Leunig
- first_name: Marie
full_name: Hoffknecht, Marie
last_name: Hoffknecht
- first_name: Kami
full_name: Pekayvaz, Kami
last_name: Pekayvaz
- first_name: Ben
full_name: Raude, Ben
last_name: Raude
- first_name: Charlotte
full_name: Marx, Charlotte
last_name: Marx
- first_name: Andreas
full_name: Ehrlich, Andreas
last_name: Ehrlich
- first_name: Joachim
full_name: Pircher, Joachim
last_name: Pircher
- first_name: Zhe
full_name: Zhang, Zhe
last_name: Zhang
- first_name: Inas
full_name: Saleh, Inas
last_name: Saleh
- first_name: Anna-Kristina
full_name: Marel, Anna-Kristina
last_name: Marel
- first_name: Achim
full_name: Löf, Achim
last_name: Löf
- first_name: Tobias
full_name: Petzold, Tobias
last_name: Petzold
- first_name: Michael
full_name: Lorenz, Michael
last_name: Lorenz
- first_name: Konstantin
full_name: Stark, Konstantin
last_name: Stark
- first_name: Robert
full_name: Pick, Robert
last_name: Pick
- first_name: Gerhild
full_name: Rosenberger, Gerhild
last_name: Rosenberger
- first_name: Ludwig
full_name: Weckbach, Ludwig
last_name: Weckbach
- first_name: Bernd
full_name: Uhl, Bernd
last_name: Uhl
- first_name: Sheng
full_name: Xia, Sheng
last_name: Xia
- first_name: Christoph Andreas
full_name: Reichel, Christoph Andreas
last_name: Reichel
- first_name: Barbara
full_name: Walzog, Barbara
last_name: Walzog
- first_name: Christian
full_name: Schulz, Christian
last_name: Schulz
- first_name: Vanessa
full_name: Zheden, Vanessa
id: 39C5A68A-F248-11E8-B48F-1D18A9856A87
last_name: Zheden
orcid: 0000-0002-9438-4783
- first_name: Markus
full_name: Bender, Markus
last_name: Bender
- first_name: Rong
full_name: Li, Rong
last_name: Li
- first_name: Steffen
full_name: Massberg, Steffen
last_name: Massberg
- first_name: Florian R
full_name: Gärtner, Florian R
id: 397A88EE-F248-11E8-B48F-1D18A9856A87
last_name: Gärtner
orcid: 0000-0001-6120-3723
citation:
ama: Nicolai L, Schiefelbein K, Lipsky S, et al. Vascular surveillance by haptotactic
blood platelets in inflammation and infection. Nature Communications. 2020;11.
doi:10.1038/s41467-020-19515-0
apa: Nicolai, L., Schiefelbein, K., Lipsky, S., Leunig, A., Hoffknecht, M., Pekayvaz,
K., … Gärtner, F. R. (2020). Vascular surveillance by haptotactic blood platelets
in inflammation and infection. Nature Communications. Springer Nature.
https://doi.org/10.1038/s41467-020-19515-0
chicago: Nicolai, Leo, Karin Schiefelbein, Silvia Lipsky, Alexander Leunig, Marie
Hoffknecht, Kami Pekayvaz, Ben Raude, et al. “Vascular Surveillance by Haptotactic
Blood Platelets in Inflammation and Infection.” Nature Communications.
Springer Nature, 2020. https://doi.org/10.1038/s41467-020-19515-0.
ieee: L. Nicolai et al., “Vascular surveillance by haptotactic blood platelets
in inflammation and infection,” Nature Communications, vol. 11. Springer
Nature, 2020.
ista: Nicolai L, Schiefelbein K, Lipsky S, Leunig A, Hoffknecht M, Pekayvaz K, Raude
B, Marx C, Ehrlich A, Pircher J, Zhang Z, Saleh I, Marel A-K, Löf A, Petzold T,
Lorenz M, Stark K, Pick R, Rosenberger G, Weckbach L, Uhl B, Xia S, Reichel CA,
Walzog B, Schulz C, Zheden V, Bender M, Li R, Massberg S, Gärtner FR. 2020. Vascular
surveillance by haptotactic blood platelets in inflammation and infection. Nature
Communications. 11, 5778.
mla: Nicolai, Leo, et al. “Vascular Surveillance by Haptotactic Blood Platelets
in Inflammation and Infection.” Nature Communications, vol. 11, 5778, Springer
Nature, 2020, doi:10.1038/s41467-020-19515-0.
short: L. Nicolai, K. Schiefelbein, S. Lipsky, A. Leunig, M. Hoffknecht, K. Pekayvaz,
B. Raude, C. Marx, A. Ehrlich, J. Pircher, Z. Zhang, I. Saleh, A.-K. Marel, A.
Löf, T. Petzold, M. Lorenz, K. Stark, R. Pick, G. Rosenberger, L. Weckbach, B.
Uhl, S. Xia, C.A. Reichel, B. Walzog, C. Schulz, V. Zheden, M. Bender, R. Li,
S. Massberg, F.R. Gärtner, Nature Communications 11 (2020).
date_created: 2020-11-22T23:01:23Z
date_published: 2020-11-13T00:00:00Z
date_updated: 2023-08-22T13:26:26Z
day: '13'
ddc:
- '570'
department:
- _id: MiSi
- _id: EM-Fac
doi: 10.1038/s41467-020-19515-0
ec_funded: 1
external_id:
isi:
- '000594648000014'
pmid:
- '33188196'
file:
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checksum: 485b7b6cf30198ba0ce126491a28f125
content_type: application/pdf
creator: dernst
date_created: 2020-11-23T13:29:49Z
date_updated: 2020-11-23T13:29:49Z
file_id: '8798'
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file_size: 7035340
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has_accepted_license: '1'
intvolume: ' 11'
isi: 1
language:
- iso: eng
month: '11'
oa: 1
oa_version: Published Version
pmid: 1
project:
- _id: 260AA4E2-B435-11E9-9278-68D0E5697425
call_identifier: H2020
grant_number: '747687'
name: Mechanical Adaptation of Lamellipodial Actin Networks in Migrating Cells
publication: Nature Communications
publication_identifier:
eissn:
- '20411723'
publication_status: published
publisher: Springer Nature
quality_controlled: '1'
related_material:
link:
- relation: erratum
url: https://doi.org/10.1038/s41467-022-31310-7
scopus_import: '1'
status: public
title: Vascular surveillance by haptotactic blood platelets in inflammation and infection
tmp:
image: /images/cc_by.png
legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
short: CC BY (4.0)
type: journal_article
user_id: 4359f0d1-fa6c-11eb-b949-802e58b17ae8
volume: 11
year: '2020'
...
---
_id: '8789'
abstract:
- lang: eng
text: Cooperation is a ubiquitous and beneficial behavioural trait despite being
prone to exploitation by free-riders. Hence, cooperative populations are prone
to invasions by selfish individuals. However, a population consisting of only
free-riders typically does not survive. Thus, cooperators and free-riders often
coexist in some proportion. An evolutionary version of a Snowdrift Game proved
its efficiency in analysing this phenomenon. However, what if the system has already
reached its stable state but was perturbed due to a change in environmental conditions?
Then, individuals may have to re-learn their effective strategies. To address
this, we consider behavioural mistakes in strategic choice execution, which we
refer to as incompetence. Parametrising the propensity to make such mistakes allows
for a mathematical description of learning. We compare strategies based on their
relative strategic advantage relying on both fitness and learning factors. When
strategies are learned at distinct rates, allowing learning according to a prescribed
order is optimal. Interestingly, the strategy with the lowest strategic advantage
should be learnt first if we are to optimise fitness over the learning path. Then,
the differences between strategies are balanced out in order to minimise the effect
of behavioural uncertainty.
acknowledgement: "This work was supported by the European Union’s Horizon 2020 research
and innovation program under the Marie Sklodowska-Curie Grant Agreement #754411,
the Australian Research Council Discovery Grants DP160101236 and DP150100618, and
the European Research Council Consolidator Grant 863818 (FoRM-SMArt).\r\nAuthors
would like to thank Patrick McKinlay for his work on the preliminary results for
this paper."
article_number: '1945'
article_processing_charge: No
article_type: original
author:
- first_name: Maria
full_name: Kleshnina, Maria
id: 4E21749C-F248-11E8-B48F-1D18A9856A87
last_name: Kleshnina
- first_name: Sabrina
full_name: Streipert, Sabrina
last_name: Streipert
- first_name: Jerzy
full_name: Filar, Jerzy
last_name: Filar
- first_name: Krishnendu
full_name: Chatterjee, Krishnendu
id: 2E5DCA20-F248-11E8-B48F-1D18A9856A87
last_name: Chatterjee
orcid: 0000-0002-4561-241X
citation:
ama: Kleshnina M, Streipert S, Filar J, Chatterjee K. Prioritised learning in snowdrift-type
games. Mathematics. 2020;8(11). doi:10.3390/math8111945
apa: Kleshnina, M., Streipert, S., Filar, J., & Chatterjee, K. (2020). Prioritised
learning in snowdrift-type games. Mathematics. MDPI. https://doi.org/10.3390/math8111945
chicago: Kleshnina, Maria, Sabrina Streipert, Jerzy Filar, and Krishnendu Chatterjee.
“Prioritised Learning in Snowdrift-Type Games.” Mathematics. MDPI, 2020.
https://doi.org/10.3390/math8111945.
ieee: M. Kleshnina, S. Streipert, J. Filar, and K. Chatterjee, “Prioritised learning
in snowdrift-type games,” Mathematics, vol. 8, no. 11. MDPI, 2020.
ista: Kleshnina M, Streipert S, Filar J, Chatterjee K. 2020. Prioritised learning
in snowdrift-type games. Mathematics. 8(11), 1945.
mla: Kleshnina, Maria, et al. “Prioritised Learning in Snowdrift-Type Games.” Mathematics,
vol. 8, no. 11, 1945, MDPI, 2020, doi:10.3390/math8111945.
short: M. Kleshnina, S. Streipert, J. Filar, K. Chatterjee, Mathematics 8 (2020).
date_created: 2020-11-22T23:01:24Z
date_published: 2020-11-04T00:00:00Z
date_updated: 2023-08-22T13:25:45Z
day: '04'
ddc:
- '000'
department:
- _id: KrCh
doi: 10.3390/math8111945
ec_funded: 1
external_id:
isi:
- '000593962100001'
file:
- access_level: open_access
checksum: 61cfcc3b35760656ce7a9385a4ace5d2
content_type: application/pdf
creator: dernst
date_created: 2020-11-23T13:06:30Z
date_updated: 2020-11-23T13:06:30Z
file_id: '8797'
file_name: 2020_Mathematics_Kleshnina.pdf
file_size: 565191
relation: main_file
success: 1
file_date_updated: 2020-11-23T13:06:30Z
has_accepted_license: '1'
intvolume: ' 8'
isi: 1
issue: '11'
language:
- iso: eng
month: '11'
oa: 1
oa_version: Published Version
project:
- _id: 260C2330-B435-11E9-9278-68D0E5697425
call_identifier: H2020
grant_number: '754411'
name: ISTplus - Postdoctoral Fellowships
- _id: 0599E47C-7A3F-11EA-A408-12923DDC885E
call_identifier: H2020
grant_number: '863818'
name: 'Formal Methods for Stochastic Models: Algorithms and Applications'
publication: Mathematics
publication_identifier:
eissn:
- '22277390'
publication_status: published
publisher: MDPI
quality_controlled: '1'
scopus_import: '1'
status: public
title: Prioritised learning in snowdrift-type games
tmp:
image: /images/cc_by.png
legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
short: CC BY (4.0)
type: journal_article
user_id: 4359f0d1-fa6c-11eb-b949-802e58b17ae8
volume: 8
year: '2020'
...
---
_id: '8287'
abstract:
- lang: eng
text: Reachability analysis aims at identifying states reachable by a system within
a given time horizon. This task is known to be computationally expensive for linear
hybrid systems. Reachability analysis works by iteratively applying continuous
and discrete post operators to compute states reachable according to continuous
and discrete dynamics, respectively. In this paper, we enhance both of these operators
and make sure that most of the involved computations are performed in low-dimensional
state space. In particular, we improve the continuous-post operator by performing
computations in high-dimensional state space only for time intervals relevant
for the subsequent application of the discrete-post operator. Furthermore, the
new discrete-post operator performs low-dimensional computations by leveraging
the structure of the guard and assignment of a considered transition. We illustrate
the potential of our approach on a number of challenging benchmarks.
article_processing_charge: No
author:
- first_name: Sergiy
full_name: Bogomolov, Sergiy
last_name: Bogomolov
- first_name: Marcelo
full_name: Forets, Marcelo
last_name: Forets
- first_name: Goran
full_name: Frehse, Goran
last_name: Frehse
- first_name: Kostiantyn
full_name: Potomkin, Kostiantyn
last_name: Potomkin
- first_name: Christian
full_name: Schilling, Christian
id: 3A2F4DCE-F248-11E8-B48F-1D18A9856A87
last_name: Schilling
orcid: 0000-0003-3658-1065
citation:
ama: 'Bogomolov S, Forets M, Frehse G, Potomkin K, Schilling C. Reachability analysis
of linear hybrid systems via block decomposition. In: Proceedings of the International
Conference on Embedded Software. ; 2020.'
apa: Bogomolov, S., Forets, M., Frehse, G., Potomkin, K., & Schilling, C. (2020).
Reachability analysis of linear hybrid systems via block decomposition. In Proceedings
of the International Conference on Embedded Software. Virtual .
chicago: Bogomolov, Sergiy, Marcelo Forets, Goran Frehse, Kostiantyn Potomkin, and
Christian Schilling. “Reachability Analysis of Linear Hybrid Systems via Block
Decomposition.” In Proceedings of the International Conference on Embedded
Software, 2020.
ieee: S. Bogomolov, M. Forets, G. Frehse, K. Potomkin, and C. Schilling, “Reachability
analysis of linear hybrid systems via block decomposition,” in Proceedings
of the International Conference on Embedded Software, Virtual , 2020.
ista: 'Bogomolov S, Forets M, Frehse G, Potomkin K, Schilling C. 2020. Reachability
analysis of linear hybrid systems via block decomposition. Proceedings of the
International Conference on Embedded Software. EMSOFT: International Conference
on Embedded Software.'
mla: Bogomolov, Sergiy, et al. “Reachability Analysis of Linear Hybrid Systems via
Block Decomposition.” Proceedings of the International Conference on Embedded
Software, 2020.
short: S. Bogomolov, M. Forets, G. Frehse, K. Potomkin, C. Schilling, in:, Proceedings
of the International Conference on Embedded Software, 2020.
conference:
end_date: 2020-09-25
location: 'Virtual '
name: 'EMSOFT: International Conference on Embedded Software'
start_date: 2020-09-20
date_created: 2020-08-24T12:56:20Z
date_published: 2020-01-01T00:00:00Z
date_updated: 2023-08-22T13:27:32Z
ddc:
- '000'
department:
- _id: ToHe
ec_funded: 1
external_id:
arxiv:
- '1905.02458'
file:
- access_level: open_access
checksum: d19e97d0f8a3a441dc078ec812297d75
content_type: application/pdf
creator: cschilli
date_created: 2020-08-24T12:53:15Z
date_updated: 2020-08-24T12:53:15Z
file_id: '8288'
file_name: 2020EMSOFT.pdf
file_size: 696384
relation: main_file
success: 1
file_date_updated: 2020-08-24T12:53:15Z
has_accepted_license: '1'
keyword:
- reachability
- hybrid systems
- decomposition
language:
- iso: eng
oa: 1
oa_version: Preprint
project:
- _id: 25832EC2-B435-11E9-9278-68D0E5697425
call_identifier: FWF
grant_number: S 11407_N23
name: Rigorous Systems Engineering
- _id: 25C5A090-B435-11E9-9278-68D0E5697425
call_identifier: FWF
grant_number: Z00312
name: The Wittgenstein Prize
- _id: 260C2330-B435-11E9-9278-68D0E5697425
call_identifier: H2020
grant_number: '754411'
name: ISTplus - Postdoctoral Fellowships
publication: Proceedings of the International Conference on Embedded Software
publication_status: published
quality_controlled: '1'
related_material:
record:
- id: '8790'
relation: later_version
status: public
status: public
title: Reachability analysis of linear hybrid systems via block decomposition
tmp:
image: /images/cc_by.png
legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
short: CC BY (4.0)
type: conference
user_id: 8b945eb4-e2f2-11eb-945a-df72226e66a9
year: '2020'
...
---
_id: '8788'
abstract:
- lang: eng
text: 'We consider a real-time setting where an environment releases sequences of
firm-deadline tasks, and an online scheduler chooses on-the-fly the ones to execute
on a single processor so as to maximize cumulated utility. The competitive ratio
is a well-known performance measure for the scheduler: it gives the worst-case
ratio, among all possible choices for the environment, of the cumulated utility
of the online scheduler versus an offline scheduler that knows these choices in
advance. Traditionally, competitive analysis is performed by hand, while automated
techniques are rare and only handle static environments with independent tasks.
We present a quantitative-verification framework for precedence-aware competitive
analysis, where task releases may depend on preceding scheduling choices, i.e.,
the environment can respond to scheduling decisions dynamically . We consider
two general classes of precedences: 1) follower precedences force the release
of a dependent task upon the completion of a set of precursor tasks, while and
2) pairing precedences modify the characteristics of a dependent task provided
the completion of a set of precursor tasks. Precedences make competitive analysis
challenging, as the online and offline schedulers operate on diverging sequences.
We make a formal presentation of our framework, and use a GPU-based implementation
to analyze ten well-known schedulers on precedence-based application examples
taken from the existing literature: 1) a handshake protocol (HP); 2) network packet-switching;
3) query scheduling (QS); and 4) a sporadic-interrupt setting. Our experimental
results show that precedences and task parameters can vary drastically the best
scheduler. Our framework thus supports application designers in choosing the best
scheduler among a given set automatically.'
acknowledgement: 'This work was supported by the Austrian Science Foundation (FWF)
under the NFN RiSE/SHiNE under Grant S11405 and Grant S11407. This article was presented
in the International Conference on Embedded Software 2020 and appears as part of
the ESWEEK-TCAD special issue. '
article_processing_charge: No
article_type: original
author:
- first_name: Andreas
full_name: Pavlogiannis, Andreas
id: 49704004-F248-11E8-B48F-1D18A9856A87
last_name: Pavlogiannis
orcid: 0000-0002-8943-0722
- first_name: Nico
full_name: Schaumberger, Nico
last_name: Schaumberger
- first_name: Ulrich
full_name: Schmid, Ulrich
last_name: Schmid
- first_name: Krishnendu
full_name: Chatterjee, Krishnendu
id: 2E5DCA20-F248-11E8-B48F-1D18A9856A87
last_name: Chatterjee
orcid: 0000-0002-4561-241X
citation:
ama: Pavlogiannis A, Schaumberger N, Schmid U, Chatterjee K. Precedence-aware automated
competitive analysis of real-time scheduling. IEEE Transactions on Computer-Aided
Design of Integrated Circuits and Systems. 2020;39(11):3981-3992. doi:10.1109/TCAD.2020.3012803
apa: Pavlogiannis, A., Schaumberger, N., Schmid, U., & Chatterjee, K. (2020).
Precedence-aware automated competitive analysis of real-time scheduling. IEEE
Transactions on Computer-Aided Design of Integrated Circuits and Systems.
IEEE. https://doi.org/10.1109/TCAD.2020.3012803
chicago: Pavlogiannis, Andreas, Nico Schaumberger, Ulrich Schmid, and Krishnendu
Chatterjee. “Precedence-Aware Automated Competitive Analysis of Real-Time Scheduling.”
IEEE Transactions on Computer-Aided Design of Integrated Circuits and Systems.
IEEE, 2020. https://doi.org/10.1109/TCAD.2020.3012803.
ieee: A. Pavlogiannis, N. Schaumberger, U. Schmid, and K. Chatterjee, “Precedence-aware
automated competitive analysis of real-time scheduling,” IEEE Transactions
on Computer-Aided Design of Integrated Circuits and Systems, vol. 39, no.
11. IEEE, pp. 3981–3992, 2020.
ista: Pavlogiannis A, Schaumberger N, Schmid U, Chatterjee K. 2020. Precedence-aware
automated competitive analysis of real-time scheduling. IEEE Transactions on Computer-Aided
Design of Integrated Circuits and Systems. 39(11), 3981–3992.
mla: Pavlogiannis, Andreas, et al. “Precedence-Aware Automated Competitive Analysis
of Real-Time Scheduling.” IEEE Transactions on Computer-Aided Design of Integrated
Circuits and Systems, vol. 39, no. 11, IEEE, 2020, pp. 3981–92, doi:10.1109/TCAD.2020.3012803.
short: A. Pavlogiannis, N. Schaumberger, U. Schmid, K. Chatterjee, IEEE Transactions
on Computer-Aided Design of Integrated Circuits and Systems 39 (2020) 3981–3992.
date_created: 2020-11-22T23:01:24Z
date_published: 2020-11-01T00:00:00Z
date_updated: 2023-08-22T13:27:05Z
day: '01'
department:
- _id: KrCh
doi: 10.1109/TCAD.2020.3012803
external_id:
isi:
- '000587712700069'
intvolume: ' 39'
isi: 1
issue: '11'
language:
- iso: eng
month: '11'
oa_version: None
page: 3981-3992
project:
- _id: 25832EC2-B435-11E9-9278-68D0E5697425
call_identifier: FWF
grant_number: S 11407_N23
name: Rigorous Systems Engineering
- _id: 25863FF4-B435-11E9-9278-68D0E5697425
call_identifier: FWF
grant_number: S11407
name: Game Theory
publication: IEEE Transactions on Computer-Aided Design of Integrated Circuits and
Systems
publication_identifier:
eissn:
- '19374151'
issn:
- '02780070'
publication_status: published
publisher: IEEE
quality_controlled: '1'
scopus_import: '1'
status: public
title: Precedence-aware automated competitive analysis of real-time scheduling
type: journal_article
user_id: 4359f0d1-fa6c-11eb-b949-802e58b17ae8
volume: 39
year: '2020'
...
---
_id: '8790'
abstract:
- lang: eng
text: Reachability analysis aims at identifying states reachable by a system within
a given time horizon. This task is known to be computationally expensive for linear
hybrid systems. Reachability analysis works by iteratively applying continuous
and discrete post operators to compute states reachable according to continuous
and discrete dynamics, respectively. In this article, we enhance both of these
operators and make sure that most of the involved computations are performed in
low-dimensional state space. In particular, we improve the continuous-post operator
by performing computations in high-dimensional state space only for time intervals
relevant for the subsequent application of the discrete-post operator. Furthermore,
the new discrete-post operator performs low-dimensional computations by leveraging
the structure of the guard and assignment of a considered transition. We illustrate
the potential of our approach on a number of challenging benchmarks.
acknowledgement: 'This research was supported in part by the Austrian Science Fund
(FWF) under grants S11402-N23 (RiSE/SHiNE) and Z211-N23 (Wittgenstein Award), the
European Union’s Horizon 2020 research and innovation programme under the Marie
Skłodowska-Curie grant agreement No. 754411, and the Air Force Office of Scientific
Research under award number FA2386-17-1-4065. Any opinions, findings, and conclusions
or recommendations expressed in this material are those of the authors and do not
necessarily reflect the views of the United States Air Force. '
article_processing_charge: No
article_type: original
author:
- first_name: Sergiy
full_name: Bogomolov, Sergiy
id: 369D9A44-F248-11E8-B48F-1D18A9856A87
last_name: Bogomolov
orcid: 0000-0002-0686-0365
- first_name: Marcelo
full_name: Forets, Marcelo
last_name: Forets
- first_name: Goran
full_name: Frehse, Goran
last_name: Frehse
- first_name: Kostiantyn
full_name: Potomkin, Kostiantyn
last_name: Potomkin
- first_name: Christian
full_name: Schilling, Christian
id: 3A2F4DCE-F248-11E8-B48F-1D18A9856A87
last_name: Schilling
orcid: 0000-0003-3658-1065
citation:
ama: Bogomolov S, Forets M, Frehse G, Potomkin K, Schilling C. Reachability analysis
of linear hybrid systems via block decomposition. IEEE Transactions on Computer-Aided
Design of Integrated Circuits and Systems. 2020;39(11):4018-4029. doi:10.1109/TCAD.2020.3012859
apa: Bogomolov, S., Forets, M., Frehse, G., Potomkin, K., & Schilling, C. (2020).
Reachability analysis of linear hybrid systems via block decomposition. IEEE
Transactions on Computer-Aided Design of Integrated Circuits and Systems.
IEEE. https://doi.org/10.1109/TCAD.2020.3012859
chicago: Bogomolov, Sergiy, Marcelo Forets, Goran Frehse, Kostiantyn Potomkin, and
Christian Schilling. “Reachability Analysis of Linear Hybrid Systems via Block
Decomposition.” IEEE Transactions on Computer-Aided Design of Integrated Circuits
and Systems. IEEE, 2020. https://doi.org/10.1109/TCAD.2020.3012859.
ieee: S. Bogomolov, M. Forets, G. Frehse, K. Potomkin, and C. Schilling, “Reachability
analysis of linear hybrid systems via block decomposition,” IEEE Transactions
on Computer-Aided Design of Integrated Circuits and Systems, vol. 39, no.
11. IEEE, pp. 4018–4029, 2020.
ista: Bogomolov S, Forets M, Frehse G, Potomkin K, Schilling C. 2020. Reachability
analysis of linear hybrid systems via block decomposition. IEEE Transactions on
Computer-Aided Design of Integrated Circuits and Systems. 39(11), 4018–4029.
mla: Bogomolov, Sergiy, et al. “Reachability Analysis of Linear Hybrid Systems via
Block Decomposition.” IEEE Transactions on Computer-Aided Design of Integrated
Circuits and Systems, vol. 39, no. 11, IEEE, 2020, pp. 4018–29, doi:10.1109/TCAD.2020.3012859.
short: S. Bogomolov, M. Forets, G. Frehse, K. Potomkin, C. Schilling, IEEE Transactions
on Computer-Aided Design of Integrated Circuits and Systems 39 (2020) 4018–4029.
date_created: 2020-11-22T23:01:25Z
date_published: 2020-11-01T00:00:00Z
date_updated: 2023-08-22T13:27:33Z
day: '01'
department:
- _id: ToHe
doi: 10.1109/TCAD.2020.3012859
ec_funded: 1
external_id:
arxiv:
- '1905.02458'
isi:
- '000587712700072'
intvolume: ' 39'
isi: 1
issue: '11'
language:
- iso: eng
main_file_link:
- open_access: '1'
url: https://arxiv.org/abs/1905.02458
month: '11'
oa: 1
oa_version: Preprint
page: 4018-4029
project:
- _id: 25832EC2-B435-11E9-9278-68D0E5697425
call_identifier: FWF
grant_number: S 11407_N23
name: Rigorous Systems Engineering
- _id: 25F42A32-B435-11E9-9278-68D0E5697425
call_identifier: FWF
grant_number: Z211
name: The Wittgenstein Prize
- _id: 260C2330-B435-11E9-9278-68D0E5697425
call_identifier: H2020
grant_number: '754411'
name: ISTplus - Postdoctoral Fellowships
publication: IEEE Transactions on Computer-Aided Design of Integrated Circuits and
Systems
publication_identifier:
eissn:
- '19374151'
issn:
- '02780070'
publication_status: published
publisher: IEEE
quality_controlled: '1'
related_material:
record:
- id: '8287'
relation: earlier_version
status: public
scopus_import: '1'
status: public
title: Reachability analysis of linear hybrid systems via block decomposition
type: journal_article
user_id: 4359f0d1-fa6c-11eb-b949-802e58b17ae8
volume: 39
year: '2020'
...
---
_id: '8924'
abstract:
- lang: eng
text: 'Maintaining fertility in a fluctuating environment is key to the reproductive
success of flowering plants. Meiosis and pollen formation are particularly sensitive
to changes in growing conditions, especially temperature. We have previously identified
cyclin-dependent kinase G1 (CDKG1) as a master regulator of temperature-dependent
meiosis and this may involve the regulation of alternative splicing (AS), including
of its own transcript. CDKG1 mRNA can undergo several AS events, potentially producing
two protein variants: CDKG1L and CDKG1S, differing in their N-terminal domain
which may be involved in co-factor interaction. In leaves, both isoforms have
distinct temperature-dependent functions on target mRNA processing, but their
role in pollen development is unknown. In the present study, we characterize the
role of CDKG1L and CDKG1S in maintaining Arabidopsis fertility. We show that the
long (L) form is necessary and sufficient to rescue the fertility defects of the
cdkg1-1 mutant, while the short (S) form is unable to rescue fertility. On the
other hand, an extra copy of CDKG1L reduces fertility. In addition, mutation of
the ATP binding pocket of the kinase indicates that kinase activity is necessary
for the function of CDKG1. Kinase mutants of CDKG1L and CDKG1S correctly localize
to the cell nucleus and nucleus and cytoplasm, respectively, but are unable to
rescue either the fertility or the splicing defects of the cdkg1-1 mutant. Furthermore,
we show that there is partial functional overlap between CDKG1 and its paralog
CDKG2 that could in part be explained by overlapping gene expression.'
acknowledgement: CN, DD, NF-F, and JD were funded by the BBSRC (grant number BB/M009459/1).
NK and AM were funded through the ERASMUS+Program. NC was funded by the VIPS Program
of the Austrian Federal Ministry of Science and Research and the City of Vienna.
article_number: '586870'
article_processing_charge: No
article_type: original
author:
- first_name: Candida
full_name: Nibau, Candida
last_name: Nibau
- first_name: Despoina
full_name: Dadarou, Despoina
last_name: Dadarou
- first_name: Nestoras
full_name: Kargios, Nestoras
last_name: Kargios
- first_name: Areti
full_name: Mallioura, Areti
last_name: Mallioura
- first_name: Narcis
full_name: Fernandez-Fuentes, Narcis
last_name: Fernandez-Fuentes
- first_name: Nicola
full_name: Cavallari, Nicola
id: 457160E6-F248-11E8-B48F-1D18A9856A87
last_name: Cavallari
- first_name: John H.
full_name: Doonan, John H.
last_name: Doonan
citation:
ama: Nibau C, Dadarou D, Kargios N, et al. A functional kinase is necessary for
cyclin-dependent kinase G1 (CDKG1) to maintain fertility at high ambient temperature
in Arabidopsis. Frontiers in Plant Science. 2020;11. doi:10.3389/fpls.2020.586870
apa: Nibau, C., Dadarou, D., Kargios, N., Mallioura, A., Fernandez-Fuentes, N.,
Cavallari, N., & Doonan, J. H. (2020). A functional kinase is necessary for
cyclin-dependent kinase G1 (CDKG1) to maintain fertility at high ambient temperature
in Arabidopsis. Frontiers in Plant Science. Frontiers. https://doi.org/10.3389/fpls.2020.586870
chicago: Nibau, Candida, Despoina Dadarou, Nestoras Kargios, Areti Mallioura, Narcis
Fernandez-Fuentes, Nicola Cavallari, and John H. Doonan. “A Functional Kinase
Is Necessary for Cyclin-Dependent Kinase G1 (CDKG1) to Maintain Fertility at High
Ambient Temperature in Arabidopsis.” Frontiers in Plant Science. Frontiers,
2020. https://doi.org/10.3389/fpls.2020.586870.
ieee: C. Nibau et al., “A functional kinase is necessary for cyclin-dependent
kinase G1 (CDKG1) to maintain fertility at high ambient temperature in Arabidopsis,”
Frontiers in Plant Science, vol. 11. Frontiers, 2020.
ista: Nibau C, Dadarou D, Kargios N, Mallioura A, Fernandez-Fuentes N, Cavallari
N, Doonan JH. 2020. A functional kinase is necessary for cyclin-dependent kinase
G1 (CDKG1) to maintain fertility at high ambient temperature in Arabidopsis. Frontiers
in Plant Science. 11, 586870.
mla: Nibau, Candida, et al. “A Functional Kinase Is Necessary for Cyclin-Dependent
Kinase G1 (CDKG1) to Maintain Fertility at High Ambient Temperature in Arabidopsis.”
Frontiers in Plant Science, vol. 11, 586870, Frontiers, 2020, doi:10.3389/fpls.2020.586870.
short: C. Nibau, D. Dadarou, N. Kargios, A. Mallioura, N. Fernandez-Fuentes, N.
Cavallari, J.H. Doonan, Frontiers in Plant Science 11 (2020).
date_created: 2020-12-06T23:01:14Z
date_published: 2020-11-10T00:00:00Z
date_updated: 2023-08-24T10:50:00Z
day: '10'
ddc:
- '580'
department:
- _id: EvBe
doi: 10.3389/fpls.2020.586870
external_id:
isi:
- '000591637000001'
file:
- access_level: open_access
checksum: 1c0ee6ce9950aa665d6a5cc64aa6b752
content_type: application/pdf
creator: dernst
date_created: 2020-12-09T09:14:19Z
date_updated: 2020-12-09T09:14:19Z
file_id: '8929'
file_name: 2020_Frontiers_Nibau.pdf
file_size: 1833244
relation: main_file
success: 1
file_date_updated: 2020-12-09T09:14:19Z
has_accepted_license: '1'
intvolume: ' 11'
isi: 1
language:
- iso: eng
month: '11'
oa: 1
oa_version: Published Version
publication: Frontiers in Plant Science
publication_identifier:
eissn:
- 1664-462X
publication_status: published
publisher: Frontiers
quality_controlled: '1'
scopus_import: '1'
status: public
title: A functional kinase is necessary for cyclin-dependent kinase G1 (CDKG1) to
maintain fertility at high ambient temperature in Arabidopsis
tmp:
image: /images/cc_by.png
legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
short: CC BY (4.0)
type: journal_article
user_id: 4359f0d1-fa6c-11eb-b949-802e58b17ae8
volume: 11
year: '2020'
...
---
_id: '8926'
abstract:
- lang: eng
text: 'Bimetallic nanoparticles with tailored size and specific composition have
shown promise as stable and selective catalysts for electrochemical reduction
of CO2 (CO2R) in batch systems. Yet, limited effort was devoted to understand
the effect of ligand coverage and postsynthesis treatments on CO2 reduction, especially
under industrially applicable conditions, such as at high currents (>100 mA/cm2)
using gas diffusion electrodes (GDE) and flow reactors. In this work, Cu–Ag core–shell
nanoparticles (11 ± 2 nm) were prepared with three different surface modes: (i)
capped with oleylamine, (ii) capped with monoisopropylamine, and (iii) surfactant-free
with a reducing borohydride agent; Cu–Ag (OAm), Cu–Ag (MIPA), and Cu–Ag (NaBH4),
respectively. The ligand exchange and removal was evidenced by infrared spectroscopy
(ATR-FTIR) analysis, whereas high-resolution scanning transmission electron microscopy
(HAADF-STEM) showed their effect on the interparticle distance and nanoparticle
rearrangement. Later on, we developed a process-on-substrate method to track these
effects on CO2R. Cu–Ag (OAm) gave a lower on-set potential for hydrocarbon production,
whereas Cu–Ag (MIPA) and Cu–Ag (NaBH4) promoted syngas production. The electrochemical
impedance and surface area analysis on the well-controlled electrodes showed gradual
increases in the electrical conductivity and active surface area after each surface
treatment. We found that the increasing amount of the triple phase boundaries
(the meeting point for the electron–electrolyte–CO2 reactant) affect the required
electrode potential and eventually the C+2e̅/C2e̅ product ratio. This study highlights
the importance of the electron transfer to those active sites affected by the
capping agents—particularly on larger substrates that are crucial for their industrial
application.'
acknowledgement: The authors also acknowledge financial support from the University
Research Fund (BOF-GOA-PS ID No. 33928). S.L. has received funding from the European
Union’s Horizon 2020 research and innovation program under the Marie Skłodowska-Curie
Grant Agreement No. 665385.
article_processing_charge: No
article_type: original
author:
- first_name: Erdem
full_name: Irtem, Erdem
last_name: Irtem
- first_name: Daniel
full_name: Arenas Esteban, Daniel
last_name: Arenas Esteban
- first_name: Miguel
full_name: Duarte, Miguel
last_name: Duarte
- first_name: Daniel
full_name: Choukroun, Daniel
last_name: Choukroun
- first_name: Seungho
full_name: Lee, Seungho
id: BB243B88-D767-11E9-B658-BC13E6697425
last_name: Lee
orcid: 0000-0002-6962-8598
- first_name: Maria
full_name: Ibáñez, Maria
id: 43C61214-F248-11E8-B48F-1D18A9856A87
last_name: Ibáñez
orcid: 0000-0001-5013-2843
- first_name: Sara
full_name: Bals, Sara
last_name: Bals
- first_name: Tom
full_name: Breugelmans, Tom
last_name: Breugelmans
citation:
ama: Irtem E, Arenas Esteban D, Duarte M, et al. Ligand-mode directed selectivity
in Cu-Ag core-shell based gas diffusion electrodes for CO2 electroreduction. ACS
Catalysis. 2020;10(22):13468-13478. doi:10.1021/acscatal.0c03210
apa: Irtem, E., Arenas Esteban, D., Duarte, M., Choukroun, D., Lee, S., Ibáñez,
M., … Breugelmans, T. (2020). Ligand-mode directed selectivity in Cu-Ag core-shell
based gas diffusion electrodes for CO2 electroreduction. ACS Catalysis.
American Chemical Society. https://doi.org/10.1021/acscatal.0c03210
chicago: Irtem, Erdem, Daniel Arenas Esteban, Miguel Duarte, Daniel Choukroun, Seungho
Lee, Maria Ibáñez, Sara Bals, and Tom Breugelmans. “Ligand-Mode Directed Selectivity
in Cu-Ag Core-Shell Based Gas Diffusion Electrodes for CO2 Electroreduction.”
ACS Catalysis. American Chemical Society, 2020. https://doi.org/10.1021/acscatal.0c03210.
ieee: E. Irtem et al., “Ligand-mode directed selectivity in Cu-Ag core-shell
based gas diffusion electrodes for CO2 electroreduction,” ACS Catalysis,
vol. 10, no. 22. American Chemical Society, pp. 13468–13478, 2020.
ista: Irtem E, Arenas Esteban D, Duarte M, Choukroun D, Lee S, Ibáñez M, Bals S,
Breugelmans T. 2020. Ligand-mode directed selectivity in Cu-Ag core-shell based
gas diffusion electrodes for CO2 electroreduction. ACS Catalysis. 10(22), 13468–13478.
mla: Irtem, Erdem, et al. “Ligand-Mode Directed Selectivity in Cu-Ag Core-Shell
Based Gas Diffusion Electrodes for CO2 Electroreduction.” ACS Catalysis,
vol. 10, no. 22, American Chemical Society, 2020, pp. 13468–78, doi:10.1021/acscatal.0c03210.
short: E. Irtem, D. Arenas Esteban, M. Duarte, D. Choukroun, S. Lee, M. Ibáñez,
S. Bals, T. Breugelmans, ACS Catalysis 10 (2020) 13468–13478.
date_created: 2020-12-06T23:01:15Z
date_published: 2020-11-20T00:00:00Z
date_updated: 2023-08-24T10:52:32Z
day: '20'
department:
- _id: MaIb
doi: 10.1021/acscatal.0c03210
ec_funded: 1
external_id:
isi:
- '000592978900031'
intvolume: ' 10'
isi: 1
issue: '22'
language:
- iso: eng
month: '11'
oa_version: None
page: 13468-13478
project:
- _id: 2564DBCA-B435-11E9-9278-68D0E5697425
call_identifier: H2020
grant_number: '665385'
name: International IST Doctoral Program
publication: ACS Catalysis
publication_identifier:
eissn:
- '21555435'
publication_status: published
publisher: American Chemical Society
quality_controlled: '1'
scopus_import: '1'
status: public
title: Ligand-mode directed selectivity in Cu-Ag core-shell based gas diffusion electrodes
for CO2 electroreduction
type: journal_article
user_id: 4359f0d1-fa6c-11eb-b949-802e58b17ae8
volume: 10
year: '2020'
...
---
_id: '8944'
abstract:
- lang: eng
text: "Superconductor insulator transition in transverse magnetic field is studied
in the highly disordered MoC film with the product of the Fermi momentum and the
mean free path kF*l close to unity. Surprisingly, the Zeeman paramagnetic effects
dominate over orbital coupling on both sides of the transition. In superconducting
state it is evidenced by a high upper critical magnetic field \U0001D435\U0001D4502,
by its square root dependence on temperature, as well as by the Zeeman splitting
of the quasiparticle density of states (DOS) measured by scanning tunneling microscopy.
At \U0001D435\U0001D4502 a logarithmic anomaly in DOS is observed. This anomaly
is further enhanced in increasing magnetic field, which is explained by the Zeeman
splitting of the Altshuler-Aronov DOS driving\r\nthe system into a more insulating
or resistive state. Spin dependent Altshuler-Aronov correction is also needed
to explain the transport behavior above \U0001D435\U0001D4502."
acknowledgement: 'We gratefully acknowledge helpful conversations with B.L. Altshuler
and R. Hlubina. The work was supported by the projects APVV-18-0358, VEGA 2/0058/20,
VEGA 1/0743/19 the European Microkelvin Platform, the COST action CA16218 (Nanocohybri)
and by U.S. Steel Košice. '
article_number: '180508'
article_processing_charge: No
article_type: original
author:
- first_name: Martin
full_name: Zemlicka, Martin
id: 2DCF8DE6-F248-11E8-B48F-1D18A9856A87
last_name: Zemlicka
- first_name: M.
full_name: Kopčík, M.
last_name: Kopčík
- first_name: P.
full_name: Szabó, P.
last_name: Szabó
- first_name: T.
full_name: Samuely, T.
last_name: Samuely
- first_name: J.
full_name: Kačmarčík, J.
last_name: Kačmarčík
- first_name: P.
full_name: Neilinger, P.
last_name: Neilinger
- first_name: M.
full_name: Grajcar, M.
last_name: Grajcar
- first_name: P.
full_name: Samuely, P.
last_name: Samuely
citation:
ama: 'Zemlicka M, Kopčík M, Szabó P, et al. Zeeman-driven superconductor-insulator
transition in strongly disordered MoC films: Scanning tunneling microscopy and
transport studies in a transverse magnetic field. Physical Review B. 2020;102(18).
doi:10.1103/PhysRevB.102.180508'
apa: 'Zemlicka, M., Kopčík, M., Szabó, P., Samuely, T., Kačmarčík, J., Neilinger,
P., … Samuely, P. (2020). Zeeman-driven superconductor-insulator transition in
strongly disordered MoC films: Scanning tunneling microscopy and transport studies
in a transverse magnetic field. Physical Review B. American Physical Society.
https://doi.org/10.1103/PhysRevB.102.180508'
chicago: 'Zemlicka, Martin, M. Kopčík, P. Szabó, T. Samuely, J. Kačmarčík, P. Neilinger,
M. Grajcar, and P. Samuely. “Zeeman-Driven Superconductor-Insulator Transition
in Strongly Disordered MoC Films: Scanning Tunneling Microscopy and Transport
Studies in a Transverse Magnetic Field.” Physical Review B. American Physical
Society, 2020. https://doi.org/10.1103/PhysRevB.102.180508.'
ieee: 'M. Zemlicka et al., “Zeeman-driven superconductor-insulator transition
in strongly disordered MoC films: Scanning tunneling microscopy and transport
studies in a transverse magnetic field,” Physical Review B, vol. 102, no.
18. American Physical Society, 2020.'
ista: 'Zemlicka M, Kopčík M, Szabó P, Samuely T, Kačmarčík J, Neilinger P, Grajcar
M, Samuely P. 2020. Zeeman-driven superconductor-insulator transition in strongly
disordered MoC films: Scanning tunneling microscopy and transport studies in a
transverse magnetic field. Physical Review B. 102(18), 180508.'
mla: 'Zemlicka, Martin, et al. “Zeeman-Driven Superconductor-Insulator Transition
in Strongly Disordered MoC Films: Scanning Tunneling Microscopy and Transport
Studies in a Transverse Magnetic Field.” Physical Review B, vol. 102, no.
18, 180508, American Physical Society, 2020, doi:10.1103/PhysRevB.102.180508.'
short: M. Zemlicka, M. Kopčík, P. Szabó, T. Samuely, J. Kačmarčík, P. Neilinger,
M. Grajcar, P. Samuely, Physical Review B 102 (2020).
date_created: 2020-12-13T23:01:21Z
date_published: 2020-11-01T00:00:00Z
date_updated: 2023-08-24T10:53:36Z
day: '01'
department:
- _id: JoFi
doi: 10.1103/PhysRevB.102.180508
external_id:
arxiv:
- '2011.04329'
isi:
- '000591509900003'
intvolume: ' 102'
isi: 1
issue: '18'
language:
- iso: eng
main_file_link:
- open_access: '1'
url: https://arxiv.org/abs/2011.04329
month: '11'
oa: 1
oa_version: Preprint
publication: Physical Review B
publication_identifier:
eissn:
- '24699969'
issn:
- '24699950'
publication_status: published
publisher: American Physical Society
quality_controlled: '1'
scopus_import: '1'
status: public
title: 'Zeeman-driven superconductor-insulator transition in strongly disordered MoC
films: Scanning tunneling microscopy and transport studies in a transverse magnetic
field'
type: journal_article
user_id: 4359f0d1-fa6c-11eb-b949-802e58b17ae8
volume: 102
year: '2020'
...
---
_id: '8955'
abstract:
- lang: eng
text: Skeletal muscle activity is continuously modulated across physiologic states
to provide coordination, flexibility and responsiveness to body tasks and external
inputs. Despite the central role the muscular system plays in facilitating vital
body functions, the network of brain-muscle interactions required to control hundreds
of muscles and synchronize their activation in relation to distinct physiologic
states has not been investigated. Recent approaches have focused on general associations
between individual brain rhythms and muscle activation during movement tasks.
However, the specific forms of coupling, the functional network of cortico-muscular
coordination, and how network structure and dynamics are modulated by autonomic
regulation across physiologic states remains unknown. To identify and quantify
the cortico-muscular interaction network and uncover basic features of neuro-autonomic
control of muscle function, we investigate the coupling between synchronous bursts
in cortical rhythms and peripheral muscle activation during sleep and wake. Utilizing
the concept of time delay stability and a novel network physiology approach, we
find that the brain-muscle network exhibits complex dynamic patterns of communication
involving multiple brain rhythms across cortical locations and different electromyographic
frequency bands. Moreover, our results show that during each physiologic state
the cortico-muscular network is characterized by a specific profile of network
links strength, where particular brain rhythms play role of main mediators of
interaction and control. Further, we discover a hierarchical reorganization in
network structure across physiologic states, with high connectivity and network
link strength during wake, intermediate during REM and light sleep, and low during
deep sleep, a sleep-stage stratification that demonstrates a unique association
between physiologic states and cortico-muscular network structure. The reported
empirical observations are consistent across individual subjects, indicating universal
behavior in network structure and dynamics, and high sensitivity of cortico-muscular
control to changes in autonomic regulation, even at low levels of physical activity
and muscle tone during sleep. Our findings demonstrate previously unrecognized
basic principles of brain-muscle network communication and control, and provide
new perspectives on the regulatory mechanisms of brain dynamics and locomotor
activation, with potential clinical implications for neurodegenerative, movement
and sleep disorders, and for developing efficient treatment strategies.
acknowledgement: We acknowledge support from the W. M. Keck Foundation, National Institutes
of Health (NIH Grant 1R01-HL098437), the US-Israel Binational Science Foundation
(BSF Grant 2012219), and the Office of Naval Research (ONR Grant 000141010078).
FL acknowledges support also from the European Union's Horizon 2020 research and
innovation program under the Marie Sklodowska-Curie Grant Agreement No. 754411.
article_number: '558070'
article_processing_charge: No
article_type: original
author:
- first_name: Rossella
full_name: Rizzo, Rossella
last_name: Rizzo
- first_name: Xiyun
full_name: Zhang, Xiyun
last_name: Zhang
- first_name: Jilin W.J.L.
full_name: Wang, Jilin W.J.L.
last_name: Wang
- first_name: Fabrizio
full_name: Lombardi, Fabrizio
id: A057D288-3E88-11E9-986D-0CF4E5697425
last_name: Lombardi
orcid: 0000-0003-2623-5249
- first_name: Plamen Ch
full_name: Ivanov, Plamen Ch
last_name: Ivanov
citation:
ama: Rizzo R, Zhang X, Wang JWJL, Lombardi F, Ivanov PC. Network physiology of cortico–muscular
interactions. Frontiers in Physiology. 2020;11. doi:10.3389/fphys.2020.558070
apa: Rizzo, R., Zhang, X., Wang, J. W. J. L., Lombardi, F., & Ivanov, P. C.
(2020). Network physiology of cortico–muscular interactions. Frontiers in Physiology.
Frontiers. https://doi.org/10.3389/fphys.2020.558070
chicago: Rizzo, Rossella, Xiyun Zhang, Jilin W.J.L. Wang, Fabrizio Lombardi, and
Plamen Ch Ivanov. “Network Physiology of Cortico–Muscular Interactions.” Frontiers
in Physiology. Frontiers, 2020. https://doi.org/10.3389/fphys.2020.558070.
ieee: R. Rizzo, X. Zhang, J. W. J. L. Wang, F. Lombardi, and P. C. Ivanov, “Network
physiology of cortico–muscular interactions,” Frontiers in Physiology,
vol. 11. Frontiers, 2020.
ista: Rizzo R, Zhang X, Wang JWJL, Lombardi F, Ivanov PC. 2020. Network physiology
of cortico–muscular interactions. Frontiers in Physiology. 11, 558070.
mla: Rizzo, Rossella, et al. “Network Physiology of Cortico–Muscular Interactions.”
Frontiers in Physiology, vol. 11, 558070, Frontiers, 2020, doi:10.3389/fphys.2020.558070.
short: R. Rizzo, X. Zhang, J.W.J.L. Wang, F. Lombardi, P.C. Ivanov, Frontiers in
Physiology 11 (2020).
date_created: 2020-12-20T23:01:18Z
date_published: 2020-11-26T00:00:00Z
date_updated: 2023-08-24T11:00:45Z
day: '26'
ddc:
- '570'
department:
- _id: GaTk
doi: 10.3389/fphys.2020.558070
ec_funded: 1
external_id:
isi:
- '000596849400001'
pmid:
- '33324233'
file:
- access_level: open_access
checksum: ef9515b28c5619b7126c0f347958bcb3
content_type: application/pdf
creator: dernst
date_created: 2020-12-21T10:37:50Z
date_updated: 2020-12-21T10:37:50Z
file_id: '8961'
file_name: 2020_Frontiers_Rizzo.pdf
file_size: 13380030
relation: main_file
success: 1
file_date_updated: 2020-12-21T10:37:50Z
has_accepted_license: '1'
intvolume: ' 11'
isi: 1
language:
- iso: eng
month: '11'
oa: 1
oa_version: Published Version
pmid: 1
project:
- _id: 260C2330-B435-11E9-9278-68D0E5697425
call_identifier: H2020
grant_number: '754411'
name: ISTplus - Postdoctoral Fellowships
publication: Frontiers in Physiology
publication_identifier:
eissn:
- 1664042X
publication_status: published
publisher: Frontiers
quality_controlled: '1'
scopus_import: '1'
status: public
title: Network physiology of cortico–muscular interactions
tmp:
image: /images/cc_by.png
legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
short: CC BY (4.0)
type: journal_article
user_id: 4359f0d1-fa6c-11eb-b949-802e58b17ae8
volume: 11
year: '2020'
...
---
_id: '8949'
abstract:
- lang: eng
text: Development of the nervous system undergoes important transitions,
including one from neurogenesis to gliogenesis which occurs late during embryonic
gestation. Here we report on clonal analysis of gliogenesis in mice using Mosaic
Analysis with Double Markers (MADM) with quantitative and computational methods.
Results reveal that developmental gliogenesis in the cerebral cortex occurs in
a fraction of earlier neurogenic clones, accelerating around E16.5, and giving
rise to both astrocytes and oligodendrocytes. Moreover, MADM-based genetic deletion
of the epidermal growth factor receptor (Egfr) in gliogenic clones revealed that
Egfr is cell autonomously required for gliogenesis in the mouse dorsolateral cortices.
A broad range in the proliferation capacity, symmetry of clones, and competitive
advantage of MADM cells was evident in clones that contained one cellular lineage
with double dosage of Egfr relative to their environment, while their sibling
Egfr-null cells failed to generate glia. Remarkably, the total numbers of glia
in MADM clones balance out regardless of significant alterations in clonal symmetries.
The variability in glial clones shows stochastic patterns that we define mathematically,
which are different from the deterministic patterns in neuronal clones. This study
sets a foundation for studying the biological significance of stochastic and deterministic
clonal principles underlying tissue development, and identifying mechanisms that
differentiate between neurogenesis and gliogenesis.
acknowledgement: This research was funded by grants from the National Institutes of
Health to H.T.G. (R01NS098370 and R01NS089795). C.V.M. was supported by a National
Science Foundation Graduate Research Fellowship (DGE-1746939). R.B. was supported
by the FWF Lise-Meitner program (M 2416), and S.H. was supported by the European
Research Council (ERC) under the European Union’s Horizon 2020 research and innovation
programme (grant agreement No 725780 LinPro).The authors thank members of the Ghashghaei
lab for discussions, technical support, and help with preparation of the manuscript.
article_number: '2662'
article_processing_charge: No
article_type: original
author:
- first_name: Xuying
full_name: Zhang, Xuying
last_name: Zhang
- first_name: Christine V.
full_name: Mennicke, Christine V.
last_name: Mennicke
- first_name: Guanxi
full_name: Xiao, Guanxi
last_name: Xiao
- first_name: Robert J
full_name: Beattie, Robert J
id: 2E26DF60-F248-11E8-B48F-1D18A9856A87
last_name: Beattie
orcid: 0000-0002-8483-8753
- first_name: Mansoor
full_name: Haider, Mansoor
last_name: Haider
- first_name: Simon
full_name: Hippenmeyer, Simon
id: 37B36620-F248-11E8-B48F-1D18A9856A87
last_name: Hippenmeyer
orcid: 0000-0003-2279-1061
- first_name: H. Troy
full_name: Ghashghaei, H. Troy
last_name: Ghashghaei
citation:
ama: Zhang X, Mennicke CV, Xiao G, et al. Clonal analysis of gliogenesis in the
cerebral cortex reveals stochastic expansion of glia and cell autonomous responses
to Egfr dosage. Cells. 2020;9(12). doi:10.3390/cells9122662
apa: Zhang, X., Mennicke, C. V., Xiao, G., Beattie, R. J., Haider, M., Hippenmeyer,
S., & Ghashghaei, H. T. (2020). Clonal analysis of gliogenesis in the cerebral
cortex reveals stochastic expansion of glia and cell autonomous responses to Egfr
dosage. Cells. MDPI. https://doi.org/10.3390/cells9122662
chicago: Zhang, Xuying, Christine V. Mennicke, Guanxi Xiao, Robert J Beattie, Mansoor
Haider, Simon Hippenmeyer, and H. Troy Ghashghaei. “Clonal Analysis of Gliogenesis
in the Cerebral Cortex Reveals Stochastic Expansion of Glia and Cell Autonomous
Responses to Egfr Dosage.” Cells. MDPI, 2020. https://doi.org/10.3390/cells9122662.
ieee: X. Zhang et al., “Clonal analysis of gliogenesis in the cerebral cortex
reveals stochastic expansion of glia and cell autonomous responses to Egfr dosage,”
Cells, vol. 9, no. 12. MDPI, 2020.
ista: Zhang X, Mennicke CV, Xiao G, Beattie RJ, Haider M, Hippenmeyer S, Ghashghaei
HT. 2020. Clonal analysis of gliogenesis in the cerebral cortex reveals stochastic
expansion of glia and cell autonomous responses to Egfr dosage. Cells. 9(12),
2662.
mla: Zhang, Xuying, et al. “Clonal Analysis of Gliogenesis in the Cerebral Cortex
Reveals Stochastic Expansion of Glia and Cell Autonomous Responses to Egfr Dosage.”
Cells, vol. 9, no. 12, 2662, MDPI, 2020, doi:10.3390/cells9122662.
short: X. Zhang, C.V. Mennicke, G. Xiao, R.J. Beattie, M. Haider, S. Hippenmeyer,
H.T. Ghashghaei, Cells 9 (2020).
date_created: 2020-12-14T08:04:03Z
date_published: 2020-12-11T00:00:00Z
date_updated: 2023-08-24T10:57:48Z
day: '11'
ddc:
- '570'
department:
- _id: SiHi
doi: 10.3390/cells9122662
ec_funded: 1
external_id:
isi:
- '000601787300001'
file:
- access_level: open_access
checksum: 5095cbdc728c9a510c5761cf60a8861c
content_type: application/pdf
creator: dernst
date_created: 2020-12-14T08:09:43Z
date_updated: 2020-12-14T08:09:43Z
file_id: '8950'
file_name: 2020_Cells_Zhang.pdf
file_size: 3504525
relation: main_file
success: 1
file_date_updated: 2020-12-14T08:09:43Z
has_accepted_license: '1'
intvolume: ' 9'
isi: 1
issue: '12'
language:
- iso: eng
month: '12'
oa: 1
oa_version: Published Version
project:
- _id: 264E56E2-B435-11E9-9278-68D0E5697425
call_identifier: FWF
grant_number: M02416
name: Molecular Mechanisms Regulating Gliogenesis in the Cerebral Cortex
- _id: 260018B0-B435-11E9-9278-68D0E5697425
call_identifier: H2020
grant_number: '725780'
name: Principles of Neural Stem Cell Lineage Progression in Cerebral Cortex Development
publication: Cells
publication_identifier:
issn:
- 2073-4409
publication_status: published
publisher: MDPI
quality_controlled: '1'
status: public
title: Clonal analysis of gliogenesis in the cerebral cortex reveals stochastic expansion
of glia and cell autonomous responses to Egfr dosage
tmp:
image: /images/cc_by.png
legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
short: CC BY (4.0)
type: journal_article
user_id: 4359f0d1-fa6c-11eb-b949-802e58b17ae8
volume: 9
year: '2020'
...