---
_id: '2813'
abstract:
- lang: eng
text: Turbulence is ubiquitous in nature, yet even for the case of ordinary Newtonian
fluids like water, our understanding of this phenomenon is limited. Many liquids
of practical importance are more complicated (e.g., blood, polymer melts, paints),
however; they exhibit elastic as well as viscous characteristics, and the relation
between stress and strain is nonlinear. We demonstrate here for a model system
of such complex fluids that at high shear rates, turbulence is not simply modified
as previously believed but is suppressed and replaced by a different type of disordered
motion, elasto-inertial turbulence. Elasto-inertial turbulence is found to occur
at much lower Reynolds numbers than Newtonian turbulence, and the dynamical properties
differ significantly. The friction scaling observed coincides with the so-called
"maximum drag reduction" asymptote, which is exhibited by a wide range
of viscoelastic fluids.
author:
- first_name: Devranjan
full_name: Samanta, Devranjan
last_name: Samanta
- first_name: Yves
full_name: Dubief, Yves
last_name: Dubief
- first_name: Markus
full_name: Holzner, Markus
last_name: Holzner
- first_name: Christof
full_name: Schäfer, Christof
last_name: Schäfer
- first_name: Alexander
full_name: Morozov, Alexander
last_name: Morozov
- first_name: Christian
full_name: Wagner, Christian
last_name: Wagner
- first_name: Björn
full_name: Hof, Björn
id: 3A374330-F248-11E8-B48F-1D18A9856A87
last_name: Hof
orcid: 0000-0003-2057-2754
citation:
ama: Samanta D, Dubief Y, Holzner M, et al. Elasto-inertial turbulence. PNAS.
2013;110(26):10557-10562. doi:10.1073/pnas.1219666110
apa: Samanta, D., Dubief, Y., Holzner, M., Schäfer, C., Morozov, A., Wagner, C.,
& Hof, B. (2013). Elasto-inertial turbulence. PNAS. National Academy
of Sciences. https://doi.org/10.1073/pnas.1219666110
chicago: Samanta, Devranjan, Yves Dubief, Markus Holzner, Christof Schäfer, Alexander
Morozov, Christian Wagner, and Björn Hof. “Elasto-Inertial Turbulence.” PNAS.
National Academy of Sciences, 2013. https://doi.org/10.1073/pnas.1219666110.
ieee: D. Samanta et al., “Elasto-inertial turbulence,” PNAS, vol.
110, no. 26. National Academy of Sciences, pp. 10557–10562, 2013.
ista: Samanta D, Dubief Y, Holzner M, Schäfer C, Morozov A, Wagner C, Hof B. 2013.
Elasto-inertial turbulence. PNAS. 110(26), 10557–10562.
mla: Samanta, Devranjan, et al. “Elasto-Inertial Turbulence.” PNAS, vol.
110, no. 26, National Academy of Sciences, 2013, pp. 10557–62, doi:10.1073/pnas.1219666110.
short: D. Samanta, Y. Dubief, M. Holzner, C. Schäfer, A. Morozov, C. Wagner, B.
Hof, PNAS 110 (2013) 10557–10562.
date_created: 2018-12-11T11:59:44Z
date_published: 2013-06-25T00:00:00Z
date_updated: 2021-01-12T06:59:54Z
day: '25'
department:
- _id: BjHo
doi: 10.1073/pnas.1219666110
external_id:
pmid:
- '23757498'
intvolume: ' 110'
issue: '26'
language:
- iso: eng
main_file_link:
- open_access: '1'
url: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3696777/
month: '06'
oa: 1
oa_version: Submitted Version
page: 10557 - 10562
pmid: 1
publication: PNAS
publication_status: published
publisher: National Academy of Sciences
publist_id: '4073'
quality_controlled: '1'
scopus_import: 1
status: public
title: Elasto-inertial turbulence
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 110
year: '2013'
...
---
_id: '2812'
abstract:
- lang: eng
text: 'We consider the problem of deciding whether the persistent homology group
of a simplicial pair (K, L) can be realized as the homology H* (X) of some complex
X with L ⊂ X ⊂ K. We show that this problem is NP-complete even if K is embedded
in ℝ3. As a consequence, we show that it is NP-hard to simplify level and sublevel
sets of scalar functions on S3 within a given tolerance constraint. This problem
has relevance to the visualization of medical images by isosurfaces. We also show
an implication to the theory of well groups of scalar functions: not every well
group can be realized by some level set, and deciding whether a well group can
be realized is NP-hard.'
acknowledgement: Some of the authors were partially supported by the GIGA ANR grant
(contract ANR-09-BLAN-0331-01) and the European project CG-Learning (contract 255827).
author:
- first_name: Dominique
full_name: Attali, Dominique
last_name: Attali
- first_name: Ulrich
full_name: Bauer, Ulrich
id: 2ADD483A-F248-11E8-B48F-1D18A9856A87
last_name: Bauer
orcid: 0000-0002-9683-0724
- first_name: Olivier
full_name: Devillers, Olivier
last_name: Devillers
- first_name: Marc
full_name: Glisse, Marc
last_name: Glisse
- first_name: André
full_name: Lieutier, André
last_name: Lieutier
citation:
ama: 'Attali D, Bauer U, Devillers O, Glisse M, Lieutier A. Homological reconstruction
and simplification in R3. In: Proceedings of the 29th Annual Symposium on Computational
Geometry. ACM; 2013:117-125. doi:10.1145/2462356.2462373'
apa: 'Attali, D., Bauer, U., Devillers, O., Glisse, M., & Lieutier, A. (2013).
Homological reconstruction and simplification in R3. In Proceedings of the
29th annual symposium on Computational Geometry (pp. 117–125). Rio de Janeiro,
Brazil: ACM. https://doi.org/10.1145/2462356.2462373'
chicago: Attali, Dominique, Ulrich Bauer, Olivier Devillers, Marc Glisse, and André
Lieutier. “Homological Reconstruction and Simplification in R3.” In Proceedings
of the 29th Annual Symposium on Computational Geometry, 117–25. ACM, 2013.
https://doi.org/10.1145/2462356.2462373.
ieee: D. Attali, U. Bauer, O. Devillers, M. Glisse, and A. Lieutier, “Homological
reconstruction and simplification in R3,” in Proceedings of the 29th annual
symposium on Computational Geometry, Rio de Janeiro, Brazil, 2013, pp. 117–125.
ista: 'Attali D, Bauer U, Devillers O, Glisse M, Lieutier A. 2013. Homological reconstruction
and simplification in R3. Proceedings of the 29th annual symposium on Computational
Geometry. SoCG: Symposium on Computational Geometry, 117–125.'
mla: Attali, Dominique, et al. “Homological Reconstruction and Simplification in
R3.” Proceedings of the 29th Annual Symposium on Computational Geometry,
ACM, 2013, pp. 117–25, doi:10.1145/2462356.2462373.
short: D. Attali, U. Bauer, O. Devillers, M. Glisse, A. Lieutier, in:, Proceedings
of the 29th Annual Symposium on Computational Geometry, ACM, 2013, pp. 117–125.
conference:
end_date: 2013-06-20
location: Rio de Janeiro, Brazil
name: 'SoCG: Symposium on Computational Geometry'
start_date: 2013-06-17
date_created: 2018-12-11T11:59:44Z
date_published: 2013-06-01T00:00:00Z
date_updated: 2023-02-23T10:15:15Z
day: '01'
department:
- _id: HeEd
doi: 10.1145/2462356.2462373
language:
- iso: eng
main_file_link:
- open_access: '1'
url: http://hal.archives-ouvertes.fr/hal-00833791/
month: '06'
oa: 1
oa_version: Submitted Version
page: 117 - 125
publication: Proceedings of the 29th annual symposium on Computational Geometry
publication_status: published
publisher: ACM
publist_id: '4072'
quality_controlled: '1'
related_material:
record:
- id: '1805'
relation: later_version
status: public
scopus_import: 1
status: public
title: Homological reconstruction and simplification in R3
type: conference
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
year: '2013'
...
---
_id: '2817'
abstract:
- lang: eng
text: The basic idea of evolutionary game theory is that payoff determines reproductive
rate. Successful individuals have a higher payoff and produce more offspring.
But in evolutionary and ecological situations there is not only reproductive rate
but also carrying capacity. Individuals may differ in their exposure to density
limiting effects. Here we explore an alternative approach to evolutionary game
theory by assuming that the payoff from the game determines the carrying capacity
of individual phenotypes. Successful strategies are less affected by density limitation
(crowding) and reach higher equilibrium abundance. We demonstrate similarities
and differences between our framework and the standard replicator equation. Our
equation is defined on the positive orthant, instead of the simplex, but has the
same equilibrium points as the replicator equation. Linear stability analysis
produces the classical conditions for asymptotic stability of pure strategies,
but the stability properties of internal equilibria can differ in the two frameworks.
For example, in a two-strategy game with an internal equilibrium that is always
stable under the replicator equation, the corresponding equilibrium can be unstable
in the new framework resulting in a limit cycle.
author:
- first_name: Sebastian
full_name: Novak, Sebastian
id: 461468AE-F248-11E8-B48F-1D18A9856A87
last_name: Novak
- first_name: Krishnendu
full_name: Chatterjee, Krishnendu
id: 2E5DCA20-F248-11E8-B48F-1D18A9856A87
last_name: Chatterjee
orcid: 0000-0002-4561-241X
- first_name: Martin
full_name: Nowak, Martin
last_name: Nowak
citation:
ama: Novak S, Chatterjee K, Nowak M. Density games. Journal of Theoretical Biology.
2013;334:26-34. doi:10.1016/j.jtbi.2013.05.029
apa: Novak, S., Chatterjee, K., & Nowak, M. (2013). Density games. Journal
of Theoretical Biology. Elsevier. https://doi.org/10.1016/j.jtbi.2013.05.029
chicago: Novak, Sebastian, Krishnendu Chatterjee, and Martin Nowak. “Density Games.”
Journal of Theoretical Biology. Elsevier, 2013. https://doi.org/10.1016/j.jtbi.2013.05.029.
ieee: S. Novak, K. Chatterjee, and M. Nowak, “Density games,” Journal of Theoretical
Biology, vol. 334. Elsevier, pp. 26–34, 2013.
ista: Novak S, Chatterjee K, Nowak M. 2013. Density games. Journal of Theoretical
Biology. 334, 26–34.
mla: Novak, Sebastian, et al. “Density Games.” Journal of Theoretical Biology,
vol. 334, Elsevier, 2013, pp. 26–34, doi:10.1016/j.jtbi.2013.05.029.
short: S. Novak, K. Chatterjee, M. Nowak, Journal of Theoretical Biology 334 (2013)
26–34.
date_created: 2018-12-11T11:59:45Z
date_published: 2013-10-07T00:00:00Z
date_updated: 2021-01-12T06:59:55Z
day: '07'
ddc:
- '000'
department:
- _id: NiBa
- _id: KrCh
doi: 10.1016/j.jtbi.2013.05.029
ec_funded: 1
file:
- access_level: open_access
checksum: 3c29059ab03a4b8f97a07646b817ddbb
content_type: application/pdf
creator: system
date_created: 2018-12-12T10:14:54Z
date_updated: 2020-07-14T12:45:49Z
file_id: '5110'
file_name: IST-2016-400-v1+1_1-s2.0-S0022519313002609-main.pdf
file_size: 834604
relation: main_file
file_date_updated: 2020-07-14T12:45:49Z
has_accepted_license: '1'
intvolume: ' 334'
language:
- iso: eng
license: https://creativecommons.org/licenses/by/4.0/
month: '10'
oa: 1
oa_version: Published Version
page: 26 - 34
project:
- _id: 25B07788-B435-11E9-9278-68D0E5697425
call_identifier: FP7
grant_number: '250152'
name: Limits to selection in biology and in evolutionary computation
- _id: 2584A770-B435-11E9-9278-68D0E5697425
call_identifier: FWF
grant_number: P 23499-N23
name: Modern Graph Algorithmic Techniques in Formal Verification
- _id: 25863FF4-B435-11E9-9278-68D0E5697425
call_identifier: FWF
grant_number: S11407
name: Game Theory
- _id: 2581B60A-B435-11E9-9278-68D0E5697425
call_identifier: FP7
grant_number: '279307'
name: 'Quantitative Graph Games: Theory and Applications'
- _id: 2587B514-B435-11E9-9278-68D0E5697425
name: Microsoft Research Faculty Fellowship
publication: Journal of Theoretical Biology
publication_status: published
publisher: Elsevier
publist_id: '3984'
pubrep_id: '400'
quality_controlled: '1'
scopus_import: 1
status: public
title: Density games
tmp:
image: /images/cc_by.png
legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
short: CC BY (4.0)
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 334
year: '2013'
...
---
_id: '2819'
abstract:
- lang: eng
text: 'We introduce quantatitive timed refinement metrics and quantitative timed
simulation functions, incorporating zenoness checks, for timed systems. These
functions assign positive real numbers between zero and infinity which quantify
the timing mismatches between two timed systems, amongst non-zeno runs. We quantify
timing mismatches in three ways: (1) the maximum timing mismatch that can arise,
(2) the "steady-state" maximum timing mismatches, where initial transient
timing mismatches are ignored; and (3) the (long-run) average timing mismatches
amongst two systems. These three kinds of mismatches constitute three important
types of timing differences. Our event times are the global times, measured from
the start of the system execution, not just the time durations of individual steps.
We present algorithms over timed automata for computing the three quantitative
simulation functions to within any desired degree of accuracy. In order to compute
the values of the quantitative simulation functions, we use a game theoretic formulation.
We introduce two new kinds of objectives for two player games on finite state
game graphs: (1) eventual debit-sum level objectives, and (2) average debit-sum
level objectives. We present algorithms for computing the optimal values for these
objectives for player 1, and then use these algorithms to compute the values of
the quantitative timed simulation functions. '
acknowledgement: 'This work has been financially supported in part by the European
Commission FP7-ICT Cognitive Systems, Interaction, and Robotics under the contract
# 270180 (NOP-TILUS); by Fundacao para Ciencia e Tecnologia under project PTDC/EEA-CRO/104901/2008
(Modeling and control of Networked vehicle systems in persistent autonomous operations);
by Austrian Science Fund (FWF) Grant No P 23499-N23 on Modern Graph Algorithmic
Techniques in Formal Verification; FWF NFN Grant No S11407-N23 (RiSE); ERC Start
grant (279307: Graph Games); and the Microsoft faculty fellows award'
author:
- first_name: Krishnendu
full_name: Chatterjee, Krishnendu
id: 2E5DCA20-F248-11E8-B48F-1D18A9856A87
last_name: Chatterjee
orcid: 0000-0002-4561-241X
- first_name: Vinayak
full_name: Prabhu, Vinayak
last_name: Prabhu
citation:
ama: 'Chatterjee K, Prabhu V. Quantitative timed simulation functions and refinement
metrics for real-time systems. In: Proceedings of the 16th International Conference
on Hybrid Systems: Computation and Control. Vol 1. Springer; 2013:273-282.
doi:10.1145/2461328.2461370'
apa: 'Chatterjee, K., & Prabhu, V. (2013). Quantitative timed simulation functions
and refinement metrics for real-time systems. In Proceedings of the 16th International
Conference on Hybrid Systems: Computation and Control (Vol. 1, pp. 273–282).
Philadelphia, PA USA: Springer. https://doi.org/10.1145/2461328.2461370'
chicago: 'Chatterjee, Krishnendu, and Vinayak Prabhu. “Quantitative Timed Simulation
Functions and Refinement Metrics for Real-Time Systems.” In Proceedings of
the 16th International Conference on Hybrid Systems: Computation and Control,
1:273–82. Springer, 2013. https://doi.org/10.1145/2461328.2461370.'
ieee: 'K. Chatterjee and V. Prabhu, “Quantitative timed simulation functions and
refinement metrics for real-time systems,” in Proceedings of the 16th International
Conference on Hybrid Systems: Computation and Control, Philadelphia, PA USA,
2013, vol. 1, pp. 273–282.'
ista: 'Chatterjee K, Prabhu V. 2013. Quantitative timed simulation functions and
refinement metrics for real-time systems. Proceedings of the 16th International
Conference on Hybrid Systems: Computation and Control. HSCC: Hybrid Systems -
Computation and Control vol. 1, 273–282.'
mla: 'Chatterjee, Krishnendu, and Vinayak Prabhu. “Quantitative Timed Simulation
Functions and Refinement Metrics for Real-Time Systems.” Proceedings of the
16th International Conference on Hybrid Systems: Computation and Control,
vol. 1, Springer, 2013, pp. 273–82, doi:10.1145/2461328.2461370.'
short: 'K. Chatterjee, V. Prabhu, in:, Proceedings of the 16th International Conference
on Hybrid Systems: Computation and Control, Springer, 2013, pp. 273–282.'
conference:
end_date: 2013-04-11
location: Philadelphia, PA USA
name: 'HSCC: Hybrid Systems - Computation and Control'
start_date: 2013-04-08
date_created: 2018-12-11T11:59:46Z
date_published: 2013-04-01T00:00:00Z
date_updated: 2021-01-12T06:59:56Z
day: '01'
department:
- _id: KrCh
doi: 10.1145/2461328.2461370
ec_funded: 1
intvolume: ' 1'
language:
- iso: eng
main_file_link:
- open_access: '1'
url: http://arxiv.org/abs/1212.6556
month: '04'
oa: 1
oa_version: Preprint
page: 273 - 282
project:
- _id: 2584A770-B435-11E9-9278-68D0E5697425
call_identifier: FWF
grant_number: P 23499-N23
name: Modern Graph Algorithmic Techniques in Formal Verification
- _id: 2581B60A-B435-11E9-9278-68D0E5697425
call_identifier: FP7
grant_number: '279307'
name: 'Quantitative Graph Games: Theory and Applications'
- _id: 25832EC2-B435-11E9-9278-68D0E5697425
call_identifier: FWF
grant_number: S 11407_N23
name: Rigorous Systems Engineering
- _id: 2587B514-B435-11E9-9278-68D0E5697425
name: Microsoft Research Faculty Fellowship
publication: 'Proceedings of the 16th International Conference on Hybrid Systems:
Computation and Control'
publication_status: published
publisher: Springer
publist_id: '3982'
quality_controlled: '1'
scopus_import: 1
status: public
title: Quantitative timed simulation functions and refinement metrics for real-time
systems
type: conference
user_id: 3E5EF7F0-F248-11E8-B48F-1D18A9856A87
volume: 1
year: '2013'
...
---
_id: '2818'
abstract:
- lang: eng
text: Models of neural responses to stimuli with complex spatiotemporal correlation
structure often assume that neurons are selective for only a small number of linear
projections of a potentially high-dimensional input. In this review, we explore
recent modeling approaches where the neural response depends on the quadratic
form of the input rather than on its linear projection, that is, the neuron is
sensitive to the local covariance structure of the signal preceding the spike.
To infer this quadratic dependence in the presence of arbitrary (e.g., naturalistic)
stimulus distribution, we review several inference methods, focusing in particular
on two information theory–based approaches (maximization of stimulus energy and
of noise entropy) and two likelihood-based approaches (Bayesian spike-triggered
covariance and extensions of generalized linear models). We analyze the formal
relationship between the likelihood-based and information-based approaches to
demonstrate how they lead to consistent inference. We demonstrate the practical
feasibility of these procedures by using model neurons responding to a flickering
variance stimulus.
author:
- first_name: Kanaka
full_name: Rajan, Kanaka
last_name: Rajan
- first_name: Olivier
full_name: Marre, Olivier
last_name: Marre
- first_name: Gasper
full_name: Tkacik, Gasper
id: 3D494DCA-F248-11E8-B48F-1D18A9856A87
last_name: Tkacik
orcid: 0000-0002-6699-1455
citation:
ama: Rajan K, Marre O, Tkačik G. Learning quadratic receptive fields from neural
responses to natural stimuli. Neural Computation. 2013;25(7):1661-1692.
doi:10.1162/NECO_a_00463
apa: Rajan, K., Marre, O., & Tkačik, G. (2013). Learning quadratic receptive
fields from neural responses to natural stimuli. Neural Computation. MIT
Press . https://doi.org/10.1162/NECO_a_00463
chicago: Rajan, Kanaka, Olivier Marre, and Gašper Tkačik. “Learning Quadratic Receptive
Fields from Neural Responses to Natural Stimuli.” Neural Computation. MIT
Press , 2013. https://doi.org/10.1162/NECO_a_00463.
ieee: K. Rajan, O. Marre, and G. Tkačik, “Learning quadratic receptive fields from
neural responses to natural stimuli,” Neural Computation, vol. 25, no.
7. MIT Press , pp. 1661–1692, 2013.
ista: Rajan K, Marre O, Tkačik G. 2013. Learning quadratic receptive fields from
neural responses to natural stimuli. Neural Computation. 25(7), 1661–1692.
mla: Rajan, Kanaka, et al. “Learning Quadratic Receptive Fields from Neural Responses
to Natural Stimuli.” Neural Computation, vol. 25, no. 7, MIT Press , 2013,
pp. 1661–92, doi:10.1162/NECO_a_00463.
short: K. Rajan, O. Marre, G. Tkačik, Neural Computation 25 (2013) 1661–1692.
date_created: 2018-12-11T11:59:45Z
date_published: 2013-07-01T00:00:00Z
date_updated: 2021-01-12T06:59:56Z
day: '01'
department:
- _id: GaTk
doi: 10.1162/NECO_a_00463
external_id:
arxiv:
- '1209.0121'
intvolume: ' 25'
issue: '7'
language:
- iso: eng
main_file_link:
- open_access: '1'
url: http://arxiv.org/abs/1209.0121
month: '07'
oa: 1
oa_version: Preprint
page: 1661 - 1692
publication: Neural Computation
publication_status: published
publisher: 'MIT Press '
publist_id: '3983'
quality_controlled: '1'
scopus_import: 1
status: public
title: Learning quadratic receptive fields from neural responses to natural stimuli
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 25
year: '2013'
...
---
_id: '2826'
abstract:
- lang: eng
text: Myopia, or near-sightedness, is an ocular refractive error of unfocused image
quality in front of the retinal plane. Individuals with high-grade myopia (dioptric
power greater than -6.00) are predisposed to ocular morbidities such as glaucoma,
retinal detachment, and myopic maculopathy. Nonsyndromic, high-grade myopia is
highly heritable, and to date multiple gene loci have been reported. We performed
exome sequencing in 4 individuals from an 11-member family of European descent
from the United States. Affected individuals had a mean dioptric spherical equivalent
of -22.00 sphere. A premature stop codon mutation c.157C>T (p.Gln53*) cosegregating
with disease was discovered within SCO2 that maps to chromosome 22q13.33. Subsequent
analyses identified three additional mutations in three highly myopic unrelated
individuals (c.341G>A, c.418G>A, and c.776C>T). To determine differential
gene expression in a developmental mouse model, we induced myopia by applying
a -15.00D lens over one eye. Messenger RNA levels of SCO2 were significantly downregulated
in myopic mouse retinae. Immunohistochemistry in mouse eyes confirmed SCO2 protein
localization in retina, retinal pigment epithelium, and sclera. SCO2 encodes for
a copper homeostasis protein influential in mitochondrial cytochrome c oxidase
activity. Copper deficiencies have been linked with photoreceptor loss and myopia
with increased scleral wall elasticity. Retinal thinning has been reported with
an SC02 variant. Human mutation identification with support from an induced myopic
animal provides biological insights of myopic development.
author:
- first_name: Khanh
full_name: Tran Viet, Khanh
last_name: Tran Viet
- first_name: Caldwell
full_name: Powell, Caldwell
last_name: Powell
- first_name: Veluchamy
full_name: Barathi, Veluchamy
last_name: Barathi
- first_name: Thomas
full_name: Klemm, Thomas
last_name: Klemm
- first_name: Sebastian
full_name: Maurer Stroh, Sebastian
last_name: Maurer Stroh
- first_name: Vachiranee
full_name: Limviphuvadh, Vachiranee
last_name: Limviphuvadh
- first_name: Vincent
full_name: Soler, Vincent
last_name: Soler
- first_name: Candice
full_name: Ho, Candice
last_name: Ho
- first_name: Tammy
full_name: Yanovitch, Tammy
last_name: Yanovitch
- first_name: Georg
full_name: Schneider, Georg
id: 329095A0-F248-11E8-B48F-1D18A9856A87
last_name: Schneider
- first_name: Yi
full_name: Li, Yi
last_name: Li
- first_name: Erica
full_name: Nading, Erica
last_name: Nading
- first_name: Ravikanth
full_name: Metlapally, Ravikanth
last_name: Metlapally
- first_name: Seang
full_name: Saw, Seang
last_name: Saw
- first_name: Liang
full_name: Goh, Liang
last_name: Goh
- first_name: Steve
full_name: Rozen, Steve
last_name: Rozen
- first_name: Terri
full_name: Young, Terri
last_name: Young
citation:
ama: Tran Viet K, Powell C, Barathi V, et al. Mutations in SCO2 are associated with
autosomal-dominant high-grade myopia. American Journal of Human Genetics.
2013;92(5):820-826. doi:10.1016/j.ajhg.2013.04.005
apa: Tran Viet, K., Powell, C., Barathi, V., Klemm, T., Maurer Stroh, S., Limviphuvadh,
V., … Young, T. (2013). Mutations in SCO2 are associated with autosomal-dominant
high-grade myopia. American Journal of Human Genetics. Cell Press. https://doi.org/10.1016/j.ajhg.2013.04.005
chicago: Tran Viet, Khanh, Caldwell Powell, Veluchamy Barathi, Thomas Klemm, Sebastian
Maurer Stroh, Vachiranee Limviphuvadh, Vincent Soler, et al. “Mutations in SCO2
Are Associated with Autosomal-Dominant High-Grade Myopia.” American Journal
of Human Genetics. Cell Press, 2013. https://doi.org/10.1016/j.ajhg.2013.04.005.
ieee: K. Tran Viet et al., “Mutations in SCO2 are associated with autosomal-dominant
high-grade myopia,” American Journal of Human Genetics, vol. 92, no. 5.
Cell Press, pp. 820–826, 2013.
ista: Tran Viet K, Powell C, Barathi V, Klemm T, Maurer Stroh S, Limviphuvadh V,
Soler V, Ho C, Yanovitch T, Schneider G, Li Y, Nading E, Metlapally R, Saw S,
Goh L, Rozen S, Young T. 2013. Mutations in SCO2 are associated with autosomal-dominant
high-grade myopia. American Journal of Human Genetics. 92(5), 820–826.
mla: Tran Viet, Khanh, et al. “Mutations in SCO2 Are Associated with Autosomal-Dominant
High-Grade Myopia.” American Journal of Human Genetics, vol. 92, no. 5,
Cell Press, 2013, pp. 820–26, doi:10.1016/j.ajhg.2013.04.005.
short: K. Tran Viet, C. Powell, V. Barathi, T. Klemm, S. Maurer Stroh, V. Limviphuvadh,
V. Soler, C. Ho, T. Yanovitch, G. Schneider, Y. Li, E. Nading, R. Metlapally,
S. Saw, L. Goh, S. Rozen, T. Young, American Journal of Human Genetics 92 (2013)
820–826.
date_created: 2018-12-11T11:59:48Z
date_published: 2013-05-02T00:00:00Z
date_updated: 2021-01-12T06:59:59Z
day: '02'
department:
- _id: MD
doi: 10.1016/j.ajhg.2013.04.005
external_id:
pmid:
- '23643385'
intvolume: ' 92'
issue: '5'
language:
- iso: eng
main_file_link:
- open_access: '1'
url: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3644634/
month: '05'
oa: 1
oa_version: Submitted Version
page: 820 - 826
pmid: 1
publication: American Journal of Human Genetics
publication_status: published
publisher: Cell Press
publist_id: '3974'
quality_controlled: '1'
scopus_import: 1
status: public
title: Mutations in SCO2 are associated with autosomal-dominant high-grade myopia
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 92
year: '2013'
...
---
_id: '2822'
abstract:
- lang: eng
text: Identification of genes that control root system architecture in crop plants
requires innovations that enable high-throughput and accurate measurements of
root system architecture through time. We demonstrate the ability of a semiautomated
3D in vivo imaging and digital phenotyping pipeline to interrogate the quantitative
genetic basis of root system growth in a rice biparental mapping population, Bala
x Azucena. We phenotyped >1,400 3D root models and >57,000 2D images for
a suite of 25 traits that quantified the distribution, shape, extent of exploration,
and the intrinsic size of root networks at days 12, 14, and 16 of growth in a
gellan gum medium. From these data we identified 89 quantitative trait loci, some
of which correspond to those found previously in soil-grown plants, and provide
evidence for genetic tradeoffs in root growth allocations, such as between the
extent and thoroughness of exploration. We also developed a multivariate method
for generating and mapping central root architecture phenotypes and used it to
identify five major quantitative trait loci (r2 = 24-37%), two of which were not
identified by our univariate analysis. Our imaging and analytical platform provides
a means to identify genes with high potential for improving root traits and agronomic
qualities of crops.
author:
- first_name: Christopher
full_name: Topp, Christopher
last_name: Topp
- first_name: Anjali
full_name: Iyer Pascuzzi, Anjali
last_name: Iyer Pascuzzi
- first_name: Jill
full_name: Anderson, Jill
last_name: Anderson
- first_name: Cheng
full_name: Lee, Cheng
last_name: Lee
- first_name: Paul
full_name: Zurek, Paul
last_name: Zurek
- first_name: Olga
full_name: Symonova, Olga
id: 3C0C7BC6-F248-11E8-B48F-1D18A9856A87
last_name: Symonova
- first_name: Ying
full_name: Zheng, Ying
last_name: Zheng
- first_name: Alexander
full_name: Bucksch, Alexander
last_name: Bucksch
- first_name: Yuriy
full_name: Mileyko, Yuriy
last_name: Mileyko
- first_name: Taras
full_name: Galkovskyi, Taras
last_name: Galkovskyi
- first_name: Brad
full_name: Moore, Brad
last_name: Moore
- first_name: John
full_name: Harer, John
last_name: Harer
- first_name: Herbert
full_name: Edelsbrunner, Herbert
id: 3FB178DA-F248-11E8-B48F-1D18A9856A87
last_name: Edelsbrunner
orcid: 0000-0002-9823-6833
- first_name: Thomas
full_name: Mitchell Olds, Thomas
last_name: Mitchell Olds
- first_name: Joshua
full_name: Weitz, Joshua
last_name: Weitz
- first_name: Philip
full_name: Benfey, Philip
last_name: Benfey
citation:
ama: Topp C, Iyer Pascuzzi A, Anderson J, et al. 3D phenotyping and quantitative
trait locus mapping identify core regions of the rice genome controlling root
architecture. PNAS. 2013;110(18):E1695-E1704. doi:10.1073/pnas.1304354110
apa: Topp, C., Iyer Pascuzzi, A., Anderson, J., Lee, C., Zurek, P., Symonova, O.,
… Benfey, P. (2013). 3D phenotyping and quantitative trait locus mapping identify
core regions of the rice genome controlling root architecture. PNAS. National
Academy of Sciences. https://doi.org/10.1073/pnas.1304354110
chicago: Topp, Christopher, Anjali Iyer Pascuzzi, Jill Anderson, Cheng Lee, Paul
Zurek, Olga Symonova, Ying Zheng, et al. “3D Phenotyping and Quantitative Trait
Locus Mapping Identify Core Regions of the Rice Genome Controlling Root Architecture.”
PNAS. National Academy of Sciences, 2013. https://doi.org/10.1073/pnas.1304354110.
ieee: C. Topp et al., “3D phenotyping and quantitative trait locus mapping
identify core regions of the rice genome controlling root architecture,” PNAS,
vol. 110, no. 18. National Academy of Sciences, pp. E1695–E1704, 2013.
ista: Topp C, Iyer Pascuzzi A, Anderson J, Lee C, Zurek P, Symonova O, Zheng Y,
Bucksch A, Mileyko Y, Galkovskyi T, Moore B, Harer J, Edelsbrunner H, Mitchell
Olds T, Weitz J, Benfey P. 2013. 3D phenotyping and quantitative trait locus mapping
identify core regions of the rice genome controlling root architecture. PNAS.
110(18), E1695–E1704.
mla: Topp, Christopher, et al. “3D Phenotyping and Quantitative Trait Locus Mapping
Identify Core Regions of the Rice Genome Controlling Root Architecture.” PNAS,
vol. 110, no. 18, National Academy of Sciences, 2013, pp. E1695–704, doi:10.1073/pnas.1304354110.
short: C. Topp, A. Iyer Pascuzzi, J. Anderson, C. Lee, P. Zurek, O. Symonova, Y.
Zheng, A. Bucksch, Y. Mileyko, T. Galkovskyi, B. Moore, J. Harer, H. Edelsbrunner,
T. Mitchell Olds, J. Weitz, P. Benfey, PNAS 110 (2013) E1695–E1704.
date_created: 2018-12-11T11:59:47Z
date_published: 2013-04-30T00:00:00Z
date_updated: 2021-01-12T06:59:58Z
day: '30'
department:
- _id: MaJö
- _id: HeEd
doi: 10.1073/pnas.1304354110
external_id:
pmid:
- '25673779'
intvolume: ' 110'
issue: '18'
language:
- iso: eng
main_file_link:
- open_access: '1'
url: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4378147/
month: '04'
oa: 1
oa_version: Submitted Version
page: E1695 - E1704
pmid: 1
publication: PNAS
publication_status: published
publisher: National Academy of Sciences
publist_id: '3979'
quality_controlled: '1'
scopus_import: 1
status: public
title: 3D phenotyping and quantitative trait locus mapping identify core regions of
the rice genome controlling root architecture
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 110
year: '2013'
...
---
_id: '2821'
abstract:
- lang: eng
text: Many key aspects of plant development are regulated by the polarized transport
of the phytohormone auxin. Cellular auxin efflux, the rate-limiting step in this
process, has been shown to rely on the coordinated action of PIN-formed (PIN)
and B-type ATP binding cassette (ABCB) carriers. Here, we report that polar auxin
transport in the Arabidopsis thaliana root also requires the action of a Major
Facilitator Superfamily (MFS) transporter, Zinc-Induced Facilitator-Like 1 (ZIFL1).
Sequencing, promoter-reporter, and fluorescent protein fusion experiments indicate
that the full-length ZIFL1.1 protein and a truncated splice isoform, ZIFL1.3,
localize to the tonoplast of root cells and the plasma membrane of leaf stomatal
guard cells, respectively. Using reverse genetics, we show that the ZIFL1.1 transporter
regulates various root auxin-related processes, while the ZIFL1.3 isoform mediates
drought tolerance by regulating stomatal closure. Auxin transport and immunolocalization
assays demonstrate that ZIFL1.1 indirectly modulates cellular auxin efflux during
shootward auxin transport at the root tip, likely by regulating plasma membrane
PIN2 abundance. Finally, heterologous expression in yeast revealed that ZIFL1.1
and ZIFL1.3 share H+-coupled K+ transport activity. Thus, by determining the subcellular
and tissue distribution of two isoforms, alternative splicing dictates a dual
function for the ZIFL1 transporter. We propose that this MFS carrier regulates
stomatal movements and polar auxin transport by modulating potassium and proton
fluxes in Arabidopsis cells.
author:
- first_name: Estelle
full_name: Remy, Estelle
last_name: Remy
- first_name: Tânia
full_name: Cabrito, Tânia
last_name: Cabrito
- first_name: Pawel
full_name: Baster, Pawel
id: 3028BD74-F248-11E8-B48F-1D18A9856A87
last_name: Baster
- first_name: Rita
full_name: Batista, Rita
last_name: Batista
- first_name: Miguel
full_name: Teixeira, Miguel
last_name: Teixeira
- first_name: Jirí
full_name: Friml, Jirí
id: 4159519E-F248-11E8-B48F-1D18A9856A87
last_name: Friml
orcid: 0000-0002-8302-7596
- first_name: Isabel
full_name: Sá Correia, Isabel
last_name: Sá Correia
- first_name: Paula
full_name: Duque, Paula
last_name: Duque
citation:
ama: Remy E, Cabrito T, Baster P, et al. A major facilitator superfamily transporter
plays a dual role in polar auxin transport and drought stress tolerance in Arabidopsis.
Plant Cell. 2013;25(3):901-926. doi:10.1105/tpc.113.110353
apa: Remy, E., Cabrito, T., Baster, P., Batista, R., Teixeira, M., Friml, J., …
Duque, P. (2013). A major facilitator superfamily transporter plays a dual role
in polar auxin transport and drought stress tolerance in Arabidopsis. Plant
Cell. American Society of Plant Biologists. https://doi.org/10.1105/tpc.113.110353
chicago: Remy, Estelle, Tânia Cabrito, Pawel Baster, Rita Batista, Miguel Teixeira,
Jiří Friml, Isabel Sá Correia, and Paula Duque. “A Major Facilitator Superfamily
Transporter Plays a Dual Role in Polar Auxin Transport and Drought Stress Tolerance
in Arabidopsis.” Plant Cell. American Society of Plant Biologists, 2013.
https://doi.org/10.1105/tpc.113.110353.
ieee: E. Remy et al., “A major facilitator superfamily transporter plays
a dual role in polar auxin transport and drought stress tolerance in Arabidopsis,”
Plant Cell, vol. 25, no. 3. American Society of Plant Biologists, pp. 901–926,
2013.
ista: Remy E, Cabrito T, Baster P, Batista R, Teixeira M, Friml J, Sá Correia I,
Duque P. 2013. A major facilitator superfamily transporter plays a dual role in
polar auxin transport and drought stress tolerance in Arabidopsis. Plant Cell.
25(3), 901–926.
mla: Remy, Estelle, et al. “A Major Facilitator Superfamily Transporter Plays a
Dual Role in Polar Auxin Transport and Drought Stress Tolerance in Arabidopsis.”
Plant Cell, vol. 25, no. 3, American Society of Plant Biologists, 2013,
pp. 901–26, doi:10.1105/tpc.113.110353.
short: E. Remy, T. Cabrito, P. Baster, R. Batista, M. Teixeira, J. Friml, I. Sá
Correia, P. Duque, Plant Cell 25 (2013) 901–926.
date_created: 2018-12-11T11:59:46Z
date_published: 2013-04-24T00:00:00Z
date_updated: 2021-01-12T06:59:57Z
day: '24'
department:
- _id: JiFr
doi: 10.1105/tpc.113.110353
external_id:
pmid:
- '23524662'
intvolume: ' 25'
issue: '3'
language:
- iso: eng
main_file_link:
- open_access: '1'
url: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3634696/
month: '04'
oa: 1
oa_version: Submitted Version
page: 901 - 926
pmid: 1
publication: Plant Cell
publication_status: published
publisher: American Society of Plant Biologists
publist_id: '3980'
quality_controlled: '1'
scopus_import: 1
status: public
title: A major facilitator superfamily transporter plays a dual role in polar auxin
transport and drought stress tolerance in Arabidopsis
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 25
year: '2013'
...
---
_id: '2827'
abstract:
- lang: eng
text: Removal of cargos from the cell surface via endocytosis is an efficient mechanism
to regulate activities of plasma membrane (PM)-resident proteins, such as receptors
or transporters. Salicylic acid (SA) is an important plant hormone that is traditionally
associated with pathogen defense. Here, we describe an unanticipated effect of
SA on subcellular endocytic cycling of proteins. Both exogenous treatments and
endogenously enhanced SA levels repressed endocytosis of different PM proteins.
The SA effect on endocytosis did not involve transcription or known components
of the SA signaling pathway for transcriptional regulation. SA likely targets
an endocytic mechanism that involves the coat protein clathrin, because SA interfered
with the clathrin incidence at the PM and clathrin-deficient mutants were less
sensitive to the impact of SA on the auxin distribution and root bending during
the gravitropic response. By contrast, SA did not affect the ligand-induced endocytosis
of the FLAGELLIN SENSING2 (FLS2) receptor during pathogen responses. Our data
suggest that the established SA impact on transcription in plant immunity and
the nontranscriptional effect of SA on clathrin-mediated endocytosis are independent
mechanisms by which SA regulates distinct aspects of plant physiology.
author:
- first_name: Yunlong
full_name: Du, Yunlong
last_name: Du
- first_name: Ricardo
full_name: Tejos, Ricardo
last_name: Tejos
- first_name: Martina
full_name: Beck, Martina
last_name: Beck
- first_name: Ellie
full_name: Himschoot, Ellie
last_name: Himschoot
- first_name: Hongjiang
full_name: Li, Hongjiang
id: 33CA54A6-F248-11E8-B48F-1D18A9856A87
last_name: Li
orcid: 0000-0001-5039-9660
- first_name: Silke
full_name: Robatzek, Silke
last_name: Robatzek
- first_name: Steffen
full_name: Vanneste, Steffen
last_name: Vanneste
- first_name: Jirí
full_name: Friml, Jirí
id: 4159519E-F248-11E8-B48F-1D18A9856A87
last_name: Friml
orcid: 0000-0002-8302-7596
citation:
ama: Du Y, Tejos R, Beck M, et al. Salicylic acid interferes with clathrin-mediated
endocytic protein trafficking. PNAS. 2013;110(19):7946-7951. doi:10.1073/pnas.1220205110
apa: Du, Y., Tejos, R., Beck, M., Himschoot, E., Li, H., Robatzek, S., … Friml,
J. (2013). Salicylic acid interferes with clathrin-mediated endocytic protein
trafficking. PNAS. National Academy of Sciences. https://doi.org/10.1073/pnas.1220205110
chicago: Du, Yunlong, Ricardo Tejos, Martina Beck, Ellie Himschoot, Hongjiang Li,
Silke Robatzek, Steffen Vanneste, and Jiří Friml. “Salicylic Acid Interferes with
Clathrin-Mediated Endocytic Protein Trafficking.” PNAS. National Academy
of Sciences, 2013. https://doi.org/10.1073/pnas.1220205110.
ieee: Y. Du et al., “Salicylic acid interferes with clathrin-mediated endocytic
protein trafficking,” PNAS, vol. 110, no. 19. National Academy of Sciences,
pp. 7946–7951, 2013.
ista: Du Y, Tejos R, Beck M, Himschoot E, Li H, Robatzek S, Vanneste S, Friml J.
2013. Salicylic acid interferes with clathrin-mediated endocytic protein trafficking.
PNAS. 110(19), 7946–7951.
mla: Du, Yunlong, et al. “Salicylic Acid Interferes with Clathrin-Mediated Endocytic
Protein Trafficking.” PNAS, vol. 110, no. 19, National Academy of Sciences,
2013, pp. 7946–51, doi:10.1073/pnas.1220205110.
short: Y. Du, R. Tejos, M. Beck, E. Himschoot, H. Li, S. Robatzek, S. Vanneste,
J. Friml, PNAS 110 (2013) 7946–7951.
date_created: 2018-12-11T11:59:48Z
date_published: 2013-05-07T00:00:00Z
date_updated: 2021-01-12T06:59:59Z
day: '07'
department:
- _id: JiFr
doi: 10.1073/pnas.1220205110
external_id:
pmid:
- '23613581'
intvolume: ' 110'
issue: '19'
language:
- iso: eng
main_file_link:
- open_access: '1'
url: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3651428/
month: '05'
oa: 1
oa_version: Submitted Version
page: 7946 - 7951
pmid: 1
project:
- _id: 2574781E-B435-11E9-9278-68D0E5697425
name: Koerber Prize 2010
publication: PNAS
publication_status: published
publisher: National Academy of Sciences
publist_id: '3972'
quality_controlled: '1'
scopus_import: 1
status: public
title: Salicylic acid interferes with clathrin-mediated endocytic protein trafficking
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 110
year: '2013'
...
---
_id: '2823'
abstract:
- lang: eng
text: The primary goal of restoration is to create self-sustaining ecological communities
that are resilient to periodic disturbance. Currently, little is known about how
restored communities respond to disturbance events such as fire and how this response
compares to remnant vegetation. Following the 2003 fires in south-eastern Australia
we examined the post-fire response of revegetation plantings and compared this
to remnant vegetation. Ten burnt and 10 unburnt (control) sites were assessed
for each of three types of vegetation (direct seeding revegetation, revegetation
using nursery seedlings (tubestock) and remnant woodland). Sixty sampling sites
were surveyed 6months after fire to quantify the initial survival of mid- and
overstorey plant species in each type of vegetation. Three and 5years after fire
all sites were resurveyed to assess vegetation structure, species diversity and
vigour, as well as indicators of soil function. Overall, revegetation showed high
(>60%) post-fire survival, but this varied among species depending on regeneration
strategy (obligate seeder or resprouter). The native ground cover, mid- and overstorey
in both types of plantings showed rapid recovery of vegetation structure and cover
within 3years of fire. This recovery was similar to the burnt remnant woodlands.
Non-native (exotic) ground cover initially increased after fire, but was no different
in burnt and unburnt sites 5years after fire. Fire had no effect on species richness,
but burnt direct seeding sites had reduced species diversity (Simpson's Diversity
Index) while diversity was higher in burnt remnant woodlands. Indices of soil
function in all types of vegetation had recovered to levels found in unburnt sites
5years after fire. These results indicate that even young revegetation (stands
<10years old) showed substantial recovery from disturbance by fire. This suggests
that revegetation can provide an important basis for restoring woodland communities
in the fire-prone Australian environment.
author:
- first_name: Melinda
full_name: Pickup, Melinda
id: 2C78037E-F248-11E8-B48F-1D18A9856A87
last_name: Pickup
orcid: 0000-0001-6118-0541
- first_name: Susie
full_name: Wilson, Susie
last_name: Wilson
- first_name: David
full_name: Freudenberger, David
last_name: Freudenberger
- first_name: Nick
full_name: Nicholls, Nick
last_name: Nicholls
- first_name: Lori
full_name: Gould, Lori
last_name: Gould
- first_name: Sarah
full_name: Hnatiuk, Sarah
last_name: Hnatiuk
- first_name: Jeni
full_name: Delandre, Jeni
last_name: Delandre
citation:
ama: Pickup M, Wilson S, Freudenberger D, et al. Post-fire recovery of revegetated
woodland communities in south-eastern Australia. Austral Ecology. 2013;38(3):300-312.
doi:10.1111/j.1442-9993.2012.02404.x
apa: Pickup, M., Wilson, S., Freudenberger, D., Nicholls, N., Gould, L., Hnatiuk,
S., & Delandre, J. (2013). Post-fire recovery of revegetated woodland communities
in south-eastern Australia. Austral Ecology. Wiley-Blackwell. https://doi.org/10.1111/j.1442-9993.2012.02404.x
chicago: Pickup, Melinda, Susie Wilson, David Freudenberger, Nick Nicholls, Lori
Gould, Sarah Hnatiuk, and Jeni Delandre. “Post-Fire Recovery of Revegetated Woodland
Communities in South-Eastern Australia.” Austral Ecology. Wiley-Blackwell,
2013. https://doi.org/10.1111/j.1442-9993.2012.02404.x.
ieee: M. Pickup et al., “Post-fire recovery of revegetated woodland communities
in south-eastern Australia,” Austral Ecology, vol. 38, no. 3. Wiley-Blackwell,
pp. 300–312, 2013.
ista: Pickup M, Wilson S, Freudenberger D, Nicholls N, Gould L, Hnatiuk S, Delandre
J. 2013. Post-fire recovery of revegetated woodland communities in south-eastern
Australia. Austral Ecology. 38(3), 300–312.
mla: Pickup, Melinda, et al. “Post-Fire Recovery of Revegetated Woodland Communities
in South-Eastern Australia.” Austral Ecology, vol. 38, no. 3, Wiley-Blackwell,
2013, pp. 300–12, doi:10.1111/j.1442-9993.2012.02404.x.
short: M. Pickup, S. Wilson, D. Freudenberger, N. Nicholls, L. Gould, S. Hnatiuk,
J. Delandre, Austral Ecology 38 (2013) 300–312.
date_created: 2018-12-11T11:59:47Z
date_published: 2013-05-01T00:00:00Z
date_updated: 2021-01-12T06:59:58Z
day: '01'
department:
- _id: NiBa
doi: 10.1111/j.1442-9993.2012.02404.x
intvolume: ' 38'
issue: '3'
language:
- iso: eng
month: '05'
oa_version: None
page: 300 - 312
publication: Austral Ecology
publication_status: published
publisher: Wiley-Blackwell
publist_id: '3978'
quality_controlled: '1'
scopus_import: 1
status: public
title: Post-fire recovery of revegetated woodland communities in south-eastern Australia
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 38
year: '2013'
...
---
_id: '2824'
abstract:
- lang: eng
text: We study synthesis of controllers for real-time systems, where the objective
is to stay in a given safe set. The problem is solved by obtaining winning strategies
in the setting of concurrent two player timed automaton games with safety objectives.
To prevent a player from winning by blocking time, we restrict each player to
strategies that ensure that the player cannot be responsible for causing a Zeno
run. We construct winning strategies for the controller which require access only
to (1) the system clocks (thus, controllers which require their own internal infinitely
precise clocks are not necessary), and (2) a logarithmic (in the number of clocks)
number of memory bits (i.e. a linear number of memory states). Precisely, we show
that for safety objectives, a memory of size (3 + lg (| C | + 1)) bits suffices
for winning controller strategies, where C is the set of clocks of the timed automaton
game, significantly improving the previous known exponential memory states bound.
We also settle the open question of whether winning region-based strategies require
memory for safety objectives by showing with an example the necessity of memory
for such strategies to win for safety objectives. Finally, we show that the decision
problem of determining if there exists a receptive player-1 winning strategy for
safety objectives is EXPTIME-complete over timed automaton games.
author:
- first_name: Krishnendu
full_name: Chatterjee, Krishnendu
id: 2E5DCA20-F248-11E8-B48F-1D18A9856A87
last_name: Chatterjee
orcid: 0000-0002-4561-241X
- first_name: Vinayak
full_name: Prabhu, Vinayak
last_name: Prabhu
citation:
ama: Chatterjee K, Prabhu V. Synthesis of memory-efficient, clock-memory free, and
non-Zeno safety controllers for timed systems. Information and Computation.
2013;228-229:83-119. doi:10.1016/j.ic.2013.04.003
apa: Chatterjee, K., & Prabhu, V. (2013). Synthesis of memory-efficient, clock-memory
free, and non-Zeno safety controllers for timed systems. Information and Computation.
Elsevier. https://doi.org/10.1016/j.ic.2013.04.003
chicago: Chatterjee, Krishnendu, and Vinayak Prabhu. “Synthesis of Memory-Efficient,
Clock-Memory Free, and Non-Zeno Safety Controllers for Timed Systems.” Information
and Computation. Elsevier, 2013. https://doi.org/10.1016/j.ic.2013.04.003.
ieee: K. Chatterjee and V. Prabhu, “Synthesis of memory-efficient, clock-memory
free, and non-Zeno safety controllers for timed systems,” Information and Computation,
vol. 228–229. Elsevier, pp. 83–119, 2013.
ista: Chatterjee K, Prabhu V. 2013. Synthesis of memory-efficient, clock-memory
free, and non-Zeno safety controllers for timed systems. Information and Computation.
228–229, 83–119.
mla: Chatterjee, Krishnendu, and Vinayak Prabhu. “Synthesis of Memory-Efficient,
Clock-Memory Free, and Non-Zeno Safety Controllers for Timed Systems.” Information
and Computation, vol. 228–229, Elsevier, 2013, pp. 83–119, doi:10.1016/j.ic.2013.04.003.
short: K. Chatterjee, V. Prabhu, Information and Computation 228–229 (2013) 83–119.
date_created: 2018-12-11T11:59:47Z
date_published: 2013-04-24T00:00:00Z
date_updated: 2021-01-12T06:59:58Z
day: '24'
department:
- _id: KrCh
doi: 10.1016/j.ic.2013.04.003
ec_funded: 1
language:
- iso: eng
month: '04'
oa_version: None
page: 83-119
project:
- _id: 2584A770-B435-11E9-9278-68D0E5697425
call_identifier: FWF
grant_number: P 23499-N23
name: Modern Graph Algorithmic Techniques in Formal Verification
- _id: 25863FF4-B435-11E9-9278-68D0E5697425
call_identifier: FWF
grant_number: S11407
name: Game Theory
- _id: 2581B60A-B435-11E9-9278-68D0E5697425
call_identifier: FP7
grant_number: '279307'
name: 'Quantitative Graph Games: Theory and Applications'
- _id: 2587B514-B435-11E9-9278-68D0E5697425
name: Microsoft Research Faculty Fellowship
publication: Information and Computation
publication_status: published
publisher: Elsevier
publist_id: '3977'
quality_controlled: '1'
scopus_import: 1
status: public
title: Synthesis of memory-efficient, clock-memory free, and non-Zeno safety controllers
for timed systems
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 228-229
year: '2013'
...
---
_id: '2832'
abstract:
- lang: eng
text: PIN-FORMED (PIN) proteins localize asymmetrically at the plasma membrane and
mediate intercellular polar transport of the plant hormone auxin that is crucial
for a multitude of developmental processes in plants. PIN localization is under
extensive control by environmental or developmental cues, but mechanisms regulating
PIN localization are not fully understood. Here we show that early endosomal components
ARF GEF BEN1 and newly identified Sec1/Munc18 family protein BEN2 are involved
in distinct steps of early endosomal trafficking. BEN1 and BEN2 are collectively
required for polar PIN localization, for their dynamic repolarization, and consequently
for auxin activity gradient formation and auxin-related developmental processes
including embryonic patterning, organogenesis, and vasculature venation patterning.
These results show that early endosomal trafficking is crucial for cell polarity
and auxin-dependent regulation of plant architecture.
article_number: e1003540
author:
- first_name: Hirokazu
full_name: Tanaka, Hirokazu
last_name: Tanaka
- first_name: Saeko
full_name: Kitakura, Saeko
last_name: Kitakura
- first_name: Hana
full_name: Rakusová, Hana
last_name: Rakusová
- first_name: Tomohiro
full_name: Uemura, Tomohiro
last_name: Uemura
- first_name: Mugurel
full_name: Feraru, Mugurel
last_name: Feraru
- first_name: Riet
full_name: De Rycke, Riet
last_name: De Rycke
- first_name: Stéphanie
full_name: Robert, Stéphanie
last_name: Robert
- first_name: Tatsuo
full_name: Kakimoto, Tatsuo
last_name: Kakimoto
- first_name: Jirí
full_name: Friml, Jirí
id: 4159519E-F248-11E8-B48F-1D18A9856A87
last_name: Friml
orcid: 0000-0002-8302-7596
citation:
ama: Tanaka H, Kitakura S, Rakusová H, et al. Cell polarity and patterning by PIN
trafficking through early endosomal compartments in arabidopsis thaliana. PLoS
Genetics. 2013;9(5). doi:10.1371/journal.pgen.1003540
apa: Tanaka, H., Kitakura, S., Rakusová, H., Uemura, T., Feraru, M., De Rycke, R.,
… Friml, J. (2013). Cell polarity and patterning by PIN trafficking through early
endosomal compartments in arabidopsis thaliana. PLoS Genetics. Public Library
of Science. https://doi.org/10.1371/journal.pgen.1003540
chicago: Tanaka, Hirokazu, Saeko Kitakura, Hana Rakusová, Tomohiro Uemura, Mugurel
Feraru, Riet De Rycke, Stéphanie Robert, Tatsuo Kakimoto, and Jiří Friml. “Cell
Polarity and Patterning by PIN Trafficking through Early Endosomal Compartments
in Arabidopsis Thaliana.” PLoS Genetics. Public Library of Science, 2013.
https://doi.org/10.1371/journal.pgen.1003540.
ieee: H. Tanaka et al., “Cell polarity and patterning by PIN trafficking
through early endosomal compartments in arabidopsis thaliana,” PLoS Genetics,
vol. 9, no. 5. Public Library of Science, 2013.
ista: Tanaka H, Kitakura S, Rakusová H, Uemura T, Feraru M, De Rycke R, Robert S,
Kakimoto T, Friml J. 2013. Cell polarity and patterning by PIN trafficking through
early endosomal compartments in arabidopsis thaliana. PLoS Genetics. 9(5), e1003540.
mla: Tanaka, Hirokazu, et al. “Cell Polarity and Patterning by PIN Trafficking through
Early Endosomal Compartments in Arabidopsis Thaliana.” PLoS Genetics, vol.
9, no. 5, e1003540, Public Library of Science, 2013, doi:10.1371/journal.pgen.1003540.
short: H. Tanaka, S. Kitakura, H. Rakusová, T. Uemura, M. Feraru, R. De Rycke, S.
Robert, T. Kakimoto, J. Friml, PLoS Genetics 9 (2013).
date_created: 2018-12-11T11:59:50Z
date_published: 2013-05-05T00:00:00Z
date_updated: 2021-01-12T07:00:03Z
day: '05'
ddc:
- '570'
department:
- _id: JiFr
doi: 10.1371/journal.pgen.1003540
ec_funded: 1
file:
- access_level: open_access
checksum: 050237d6c53e8d1601b26808ee1dd6d8
content_type: application/pdf
creator: system
date_created: 2018-12-12T10:12:39Z
date_updated: 2020-07-14T12:45:50Z
file_id: '4957'
file_name: IST-2016-411-v1+1_journal.pgen.1003540.pdf
file_size: 3813091
relation: main_file
file_date_updated: 2020-07-14T12:45:50Z
has_accepted_license: '1'
intvolume: ' 9'
issue: '5'
language:
- iso: eng
month: '05'
oa: 1
oa_version: Published Version
project:
- _id: 25716A02-B435-11E9-9278-68D0E5697425
call_identifier: FP7
grant_number: '282300'
name: Polarity and subcellular dynamics in plants
publication: PLoS Genetics
publication_status: published
publisher: Public Library of Science
publist_id: '3967'
pubrep_id: '411'
quality_controlled: '1'
scopus_import: 1
status: public
title: Cell polarity and patterning by PIN trafficking through early endosomal compartments
in arabidopsis thaliana
tmp:
image: /images/cc_by.png
legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
short: CC BY (4.0)
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 9
year: '2013'
...
---
_id: '2828'
abstract:
- lang: eng
text: 'We study the complexity of valued constraint satisfaction problems (VCSPs)
parametrized by a constraint language, a fixed set of cost functions over a finite
domain. An instance of the problem is specified by a sum of cost functions from
the language and the goal is to minimize the sum. Under the unique games conjecture,
the approximability of finite-valued VCSPs is well understood, see Raghavendra
[2008]. However, there is no characterization of finite-valued VCSPs, let alone
general-valued VCSPs, that can be solved exactly in polynomial time, thus giving
insights from a combinatorial optimization perspective. We consider the case of
languages containing all possible unary cost functions. In the case of languages
consisting of only {0, ∞}-valued cost functions (i.e., relations), such languages
have been called conservative and studied by Bulatov [2003, 2011] and recently
by Barto [2011]. Since we study valued languages, we call a language conservative
if it contains all finite-valued unary cost functions. The computational complexity
of conservative valued languages has been studied by Cohen et al. [2006] for languages
over Boolean domains, by Deineko et al. [2008] for {0, 1}-valued languages (a.k.a
Max-CSP), and by Takhanov [2010a] for {0, ∞}-valued languages containing all finite-valued
unary cost functions (a.k.a. Min-Cost-Hom). We prove a Schaefer-like dichotomy
theorem for conservative valued languages: if all cost functions in the language
satisfy a certain condition (specified by a complementary combination of STP and
MJN multimor-phisms), then any instance can be solved in polynomial time (via
a new algorithm developed in this article), otherwise the language is NP-hard.
This is the first complete complexity classification of general-valued constraint
languages over non-Boolean domains. It is a common phenomenon that complexity
classifications of problems over non-Boolean domains are significantly harder
than the Boolean cases. The polynomial-time algorithm we present for the tractable
cases is a generalization of the submodular minimization problem and a result
of Cohen et al. [2008]. Our results generalize previous results by Takhanov [2010a]
and (a subset of results) by Cohen et al. [2006] and Deineko et al. [2008]. Moreover,
our results do not rely on any computer-assisted search as in Deineko et al. [2008],
and provide a powerful tool for proving hardness of finite-valued and general-valued
languages.'
article_number: '10'
author:
- first_name: Vladimir
full_name: Kolmogorov, Vladimir
id: 3D50B0BA-F248-11E8-B48F-1D18A9856A87
last_name: Kolmogorov
- first_name: Stanislav
full_name: Živný, Stanislav
last_name: Živný
citation:
ama: Kolmogorov V, Živný S. The complexity of conservative valued CSPs. Journal
of the ACM. 2013;60(2). doi:10.1145/2450142.2450146
apa: Kolmogorov, V., & Živný, S. (2013). The complexity of conservative valued
CSPs. Journal of the ACM. ACM. https://doi.org/10.1145/2450142.2450146
chicago: Kolmogorov, Vladimir, and Stanislav Živný. “The Complexity of Conservative
Valued CSPs.” Journal of the ACM. ACM, 2013. https://doi.org/10.1145/2450142.2450146.
ieee: V. Kolmogorov and S. Živný, “The complexity of conservative valued CSPs,”
Journal of the ACM, vol. 60, no. 2. ACM, 2013.
ista: Kolmogorov V, Živný S. 2013. The complexity of conservative valued CSPs. Journal
of the ACM. 60(2), 10.
mla: Kolmogorov, Vladimir, and Stanislav Živný. “The Complexity of Conservative
Valued CSPs.” Journal of the ACM, vol. 60, no. 2, 10, ACM, 2013, doi:10.1145/2450142.2450146.
short: V. Kolmogorov, S. Živný, Journal of the ACM 60 (2013).
date_created: 2018-12-11T11:59:48Z
date_published: 2013-04-02T00:00:00Z
date_updated: 2021-01-12T07:00:00Z
day: '02'
department:
- _id: VlKo
doi: 10.1145/2450142.2450146
external_id:
arxiv:
- '1110.2809'
intvolume: ' 60'
issue: '2'
language:
- iso: eng
main_file_link:
- open_access: '1'
url: http://arxiv.org/abs/1110.2809
month: '04'
oa: 1
oa_version: Preprint
publication: Journal of the ACM
publication_status: published
publisher: ACM
publist_id: '3971'
quality_controlled: '1'
scopus_import: 1
status: public
title: The complexity of conservative valued CSPs
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 60
year: '2013'
...
---
_id: '2829'
abstract:
- lang: eng
text: Laminar-turbulent intermittency is intrinsic to the transitional regime of
a wide range of fluid flows including pipe, channel, boundary layer, and Couette
flow. In the latter turbulent spots can grow and form continuous stripes, yet
in the stripe-normal direction they remain interspersed by laminar fluid. We carry
out direct numerical simulations in a long narrow domain and observe that individual
turbulent stripes are transient. In agreement with recent observations in pipe
flow, we find that turbulence becomes sustained at a distinct critical point once
the spatial proliferation outweighs the inherent decaying process. By resolving
the asymptotic size distributions close to criticality we can for the first time
demonstrate scale invariance at the onset of turbulence.
article_number: '204502'
author:
- first_name: Liang
full_name: Shi, Liang
id: 374A3F1A-F248-11E8-B48F-1D18A9856A87
last_name: Shi
- first_name: Marc
full_name: Avila, Marc
last_name: Avila
- first_name: Björn
full_name: Hof, Björn
id: 3A374330-F248-11E8-B48F-1D18A9856A87
last_name: Hof
orcid: 0000-0003-2057-2754
citation:
ama: Shi L, Avila M, Hof B. Scale invariance at the onset of turbulence in couette
flow. Physical Review Letters. 2013;110(20). doi:10.1103/PhysRevLett.110.204502
apa: Shi, L., Avila, M., & Hof, B. (2013). Scale invariance at the onset of
turbulence in couette flow. Physical Review Letters. American Physical
Society. https://doi.org/10.1103/PhysRevLett.110.204502
chicago: Shi, Liang, Marc Avila, and Björn Hof. “Scale Invariance at the Onset of
Turbulence in Couette Flow.” Physical Review Letters. American Physical
Society, 2013. https://doi.org/10.1103/PhysRevLett.110.204502.
ieee: L. Shi, M. Avila, and B. Hof, “Scale invariance at the onset of turbulence
in couette flow,” Physical Review Letters, vol. 110, no. 20. American Physical
Society, 2013.
ista: Shi L, Avila M, Hof B. 2013. Scale invariance at the onset of turbulence in
couette flow. Physical Review Letters. 110(20), 204502.
mla: Shi, Liang, et al. “Scale Invariance at the Onset of Turbulence in Couette
Flow.” Physical Review Letters, vol. 110, no. 20, 204502, American Physical
Society, 2013, doi:10.1103/PhysRevLett.110.204502.
short: L. Shi, M. Avila, B. Hof, Physical Review Letters 110 (2013).
date_created: 2018-12-11T11:59:49Z
date_published: 2013-05-13T00:00:00Z
date_updated: 2021-01-12T07:00:00Z
day: '13'
department:
- _id: BjHo
doi: 10.1103/PhysRevLett.110.204502
ec_funded: 1
external_id:
arxiv:
- '1304.5446'
intvolume: ' 110'
issue: '20'
language:
- iso: eng
main_file_link:
- open_access: '1'
url: http://arxiv.org/abs/1304.5446
month: '05'
oa: 1
oa_version: Preprint
project:
- _id: 25152F3A-B435-11E9-9278-68D0E5697425
call_identifier: FP7
grant_number: '306589'
name: Decoding the complexity of turbulence at its origin
- _id: 2511D90C-B435-11E9-9278-68D0E5697425
grant_number: SFB 963 TP A8
name: Astrophysical instability of currents and turbulences
publication: Physical Review Letters
publication_status: published
publisher: American Physical Society
publist_id: '3970'
quality_controlled: '1'
scopus_import: 1
status: public
title: Scale invariance at the onset of turbulence in couette flow
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 110
year: '2013'
...
---
_id: '2834'
abstract:
- lang: eng
text: Although the equations governing fluid flow are well known, there are no analytical
expressions that describe the complexity of turbulent motion. A recent proposition
is that in analogy to low dimensional chaotic systems, turbulence is organized
around unstable solutions of the governing equations which provide the building
blocks of the disordered dynamics. We report the discovery of periodic solutions
which just like intermittent turbulence are spatially localized and show that
turbulent transients arise from one such solution branch.
article_number: '224502'
author:
- first_name: Marc
full_name: Avila, Marc
last_name: Avila
- first_name: Fernando
full_name: Mellibovsky, Fernando
last_name: Mellibovsky
- first_name: Nicolas
full_name: Roland, Nicolas
last_name: Roland
- first_name: Björn
full_name: Hof, Björn
id: 3A374330-F248-11E8-B48F-1D18A9856A87
last_name: Hof
orcid: 0000-0003-2057-2754
citation:
ama: Avila M, Mellibovsky F, Roland N, Hof B. Streamwise-localized solutions at
the onset of turbulence in pipe flow. Physical Review Letters. 2013;110(22).
doi:10.1103/PhysRevLett.110.224502
apa: Avila, M., Mellibovsky, F., Roland, N., & Hof, B. (2013). Streamwise-localized
solutions at the onset of turbulence in pipe flow. Physical Review Letters.
American Physical Society. https://doi.org/10.1103/PhysRevLett.110.224502
chicago: Avila, Marc, Fernando Mellibovsky, Nicolas Roland, and Björn Hof. “Streamwise-Localized
Solutions at the Onset of Turbulence in Pipe Flow.” Physical Review Letters.
American Physical Society, 2013. https://doi.org/10.1103/PhysRevLett.110.224502.
ieee: M. Avila, F. Mellibovsky, N. Roland, and B. Hof, “Streamwise-localized solutions
at the onset of turbulence in pipe flow,” Physical Review Letters, vol.
110, no. 22. American Physical Society, 2013.
ista: Avila M, Mellibovsky F, Roland N, Hof B. 2013. Streamwise-localized solutions
at the onset of turbulence in pipe flow. Physical Review Letters. 110(22), 224502.
mla: Avila, Marc, et al. “Streamwise-Localized Solutions at the Onset of Turbulence
in Pipe Flow.” Physical Review Letters, vol. 110, no. 22, 224502, American
Physical Society, 2013, doi:10.1103/PhysRevLett.110.224502.
short: M. Avila, F. Mellibovsky, N. Roland, B. Hof, Physical Review Letters 110
(2013).
date_created: 2018-12-11T11:59:50Z
date_published: 2013-05-29T00:00:00Z
date_updated: 2021-01-12T07:00:05Z
day: '29'
department:
- _id: BjHo
doi: 10.1103/PhysRevLett.110.224502
ec_funded: 1
external_id:
arxiv:
- '1212.0230'
intvolume: ' 110'
issue: '22'
language:
- iso: eng
main_file_link:
- open_access: '1'
url: http://arxiv.org/abs/1212.0230
month: '05'
oa: 1
oa_version: Preprint
project:
- _id: 25152F3A-B435-11E9-9278-68D0E5697425
call_identifier: FP7
grant_number: '306589'
name: Decoding the complexity of turbulence at its origin
publication: Physical Review Letters
publication_status: published
publisher: American Physical Society
publist_id: '3965'
quality_controlled: '1'
scopus_import: 1
status: public
title: Streamwise-localized solutions at the onset of turbulence in pipe flow
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 110
year: '2013'
...
---
_id: '2833'
abstract:
- lang: eng
text: During development, mechanical forces cause changes in size, shape, number,
position, and gene expression of cells. They are therefore integral to any morphogenetic
processes. Force generation by actin-myosin networks and force transmission through
adhesive complexes are two self-organizing phenomena driving tissue morphogenesis.
Coordination and integration of forces by long-range force transmission and mechanosensing
of cells within tissues produce large-scale tissue shape changes. Extrinsic mechanical
forces also control tissue patterning by modulating cell fate specification and
differentiation. Thus, the interplay between tissue mechanics and biochemical
signaling orchestrates tissue morphogenesis and patterning in development.
acknowledgement: C.-P.H. is supported by the Institute of Science and Technology Austria
and grants from the Deutsche Forschungsgemeinschaft (DFG) and Fonds zur Förderung
der wissenschaftlichen Forschung (FWF).
author:
- first_name: Carl-Philipp J
full_name: Heisenberg, Carl-Philipp J
id: 39427864-F248-11E8-B48F-1D18A9856A87
last_name: Heisenberg
orcid: 0000-0002-0912-4566
- first_name: Yohanns
full_name: Bellaïche, Yohanns
last_name: Bellaïche
citation:
ama: Heisenberg C-PJ, Bellaïche Y. Forces in tissue morphogenesis and patterning.
Cell. 2013;153(5):948-962. doi:10.1016/j.cell.2013.05.008
apa: Heisenberg, C.-P. J., & Bellaïche, Y. (2013). Forces in tissue morphogenesis
and patterning. Cell. Cell Press. https://doi.org/10.1016/j.cell.2013.05.008
chicago: Heisenberg, Carl-Philipp J, and Yohanns Bellaïche. “Forces in Tissue Morphogenesis
and Patterning.” Cell. Cell Press, 2013. https://doi.org/10.1016/j.cell.2013.05.008.
ieee: C.-P. J. Heisenberg and Y. Bellaïche, “Forces in tissue morphogenesis and
patterning,” Cell, vol. 153, no. 5. Cell Press, pp. 948–962, 2013.
ista: Heisenberg C-PJ, Bellaïche Y. 2013. Forces in tissue morphogenesis and patterning.
Cell. 153(5), 948–962.
mla: Heisenberg, Carl-Philipp J., and Yohanns Bellaïche. “Forces in Tissue Morphogenesis
and Patterning.” Cell, vol. 153, no. 5, Cell Press, 2013, pp. 948–62, doi:10.1016/j.cell.2013.05.008.
short: C.-P.J. Heisenberg, Y. Bellaïche, Cell 153 (2013) 948–962.
date_created: 2018-12-11T11:59:50Z
date_published: 2013-05-23T00:00:00Z
date_updated: 2021-01-12T07:00:04Z
day: '23'
department:
- _id: CaHe
doi: 10.1016/j.cell.2013.05.008
intvolume: ' 153'
issue: '5'
language:
- iso: eng
month: '05'
oa_version: None
page: 948 - 962
publication: Cell
publication_status: published
publisher: Cell Press
publist_id: '3966'
quality_controlled: '1'
scopus_import: 1
status: public
title: Forces in tissue morphogenesis and patterning
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 153
year: '2013'
...
---
_id: '2830'
author:
- first_name: Christine
full_name: Moussion, Christine
id: 3356F664-F248-11E8-B48F-1D18A9856A87
last_name: Moussion
- first_name: Michael K
full_name: Sixt, Michael K
id: 41E9FBEA-F248-11E8-B48F-1D18A9856A87
last_name: Sixt
orcid: 0000-0002-6620-9179
citation:
ama: Moussion C, Sixt MK. A conduit to amplify innate immunity. Immunity.
2013;38(5):853-854. doi:10.1016/j.immuni.2013.05.005
apa: Moussion, C., & Sixt, M. K. (2013). A conduit to amplify innate immunity.
Immunity. Cell Press. https://doi.org/10.1016/j.immuni.2013.05.005
chicago: Moussion, Christine, and Michael K Sixt. “A Conduit to Amplify Innate Immunity.”
Immunity. Cell Press, 2013. https://doi.org/10.1016/j.immuni.2013.05.005.
ieee: C. Moussion and M. K. Sixt, “A conduit to amplify innate immunity,” Immunity,
vol. 38, no. 5. Cell Press, pp. 853–854, 2013.
ista: Moussion C, Sixt MK. 2013. A conduit to amplify innate immunity. Immunity.
38(5), 853–854.
mla: Moussion, Christine, and Michael K. Sixt. “A Conduit to Amplify Innate Immunity.”
Immunity, vol. 38, no. 5, Cell Press, 2013, pp. 853–54, doi:10.1016/j.immuni.2013.05.005.
short: C. Moussion, M.K. Sixt, Immunity 38 (2013) 853–854.
date_created: 2018-12-11T11:59:49Z
date_published: 2013-05-23T00:00:00Z
date_updated: 2021-01-12T07:00:01Z
day: '23'
department:
- _id: MiSi
doi: 10.1016/j.immuni.2013.05.005
intvolume: ' 38'
issue: '5'
language:
- iso: eng
month: '05'
oa_version: None
page: 853 - 854
publication: Immunity
publication_status: published
publisher: Cell Press
publist_id: '3969'
quality_controlled: '1'
scopus_import: 1
status: public
title: A conduit to amplify innate immunity
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 38
year: '2013'
...
---
_id: '2842'
abstract:
- lang: eng
text: 'We outline two approaches to inference of neighbourhood size, N, and dispersal
rate, σ2, based on either allele frequencies or on the lengths of sequence blocks
that are shared between genomes. Over intermediate timescales (10-100 generations,
say), populations that live in two dimensions approach a quasi-equilibrium that
is independent of both their local structure and their deeper history. Over such
scales, the standardised covariance of allele frequencies (i.e. pairwise FS T)
falls with the logarithm of distance, and depends only on neighbourhood size,
N, and a ''local scale'', κ; the rate of gene flow, σ2, cannot be inferred. We
show how spatial correlations can be accounted for, assuming a Gaussian distribution
of allele frequencies, giving maximum likelihood estimates of N and κ. Alternatively,
inferences can be based on the distribution of the lengths of sequence that are
identical between blocks of genomes: long blocks (>0.1 cM, say) tell us about
intermediate timescales, over which we assume a quasi-equilibrium. For large neighbourhood
size, the distribution of long blocks is given directly by the classical Wright-Malécot
formula; this relationship can be used to infer both N and σ2. With small neighbourhood
size, there is an appreciable chance that recombinant lineages will coalesce back
before escaping into the distant past. For this case, we show that if genomes
are sampled from some distance apart, then the distribution of lengths of blocks
that are identical in state is geometric, with a mean that depends on N and σ2.'
author:
- first_name: Nicholas H
full_name: Barton, Nicholas H
id: 4880FE40-F248-11E8-B48F-1D18A9856A87
last_name: Barton
orcid: 0000-0002-8548-5240
- first_name: Alison
full_name: Etheridge, Alison
last_name: Etheridge
- first_name: Jerome
full_name: Kelleher, Jerome
last_name: Kelleher
- first_name: Amandine
full_name: Véber, Amandine
last_name: Véber
citation:
ama: 'Barton NH, Etheridge A, Kelleher J, Véber A. Inference in two dimensions:
Allele frequencies versus lengths of shared sequence blocks. Theoretical Population
Biology. 2013;87(1):105-119. doi:10.1016/j.tpb.2013.03.001'
apa: 'Barton, N. H., Etheridge, A., Kelleher, J., & Véber, A. (2013). Inference
in two dimensions: Allele frequencies versus lengths of shared sequence blocks.
Theoretical Population Biology. Elsevier. https://doi.org/10.1016/j.tpb.2013.03.001'
chicago: 'Barton, Nicholas H, Alison Etheridge, Jerome Kelleher, and Amandine Véber.
“Inference in Two Dimensions: Allele Frequencies versus Lengths of Shared Sequence
Blocks.” Theoretical Population Biology. Elsevier, 2013. https://doi.org/10.1016/j.tpb.2013.03.001.'
ieee: 'N. H. Barton, A. Etheridge, J. Kelleher, and A. Véber, “Inference in two
dimensions: Allele frequencies versus lengths of shared sequence blocks,” Theoretical
Population Biology, vol. 87, no. 1. Elsevier, pp. 105–119, 2013.'
ista: 'Barton NH, Etheridge A, Kelleher J, Véber A. 2013. Inference in two dimensions:
Allele frequencies versus lengths of shared sequence blocks. Theoretical Population
Biology. 87(1), 105–119.'
mla: 'Barton, Nicholas H., et al. “Inference in Two Dimensions: Allele Frequencies
versus Lengths of Shared Sequence Blocks.” Theoretical Population Biology,
vol. 87, no. 1, Elsevier, 2013, pp. 105–19, doi:10.1016/j.tpb.2013.03.001.'
short: N.H. Barton, A. Etheridge, J. Kelleher, A. Véber, Theoretical Population
Biology 87 (2013) 105–119.
date_created: 2018-12-11T11:59:53Z
date_published: 2013-08-01T00:00:00Z
date_updated: 2021-01-12T07:00:09Z
day: '01'
ddc:
- '570'
department:
- _id: NiBa
doi: 10.1016/j.tpb.2013.03.001
ec_funded: 1
file:
- access_level: open_access
checksum: 9bf9d9a6fd03dd9df50906891f393bf8
content_type: application/pdf
creator: system
date_created: 2018-12-12T10:17:33Z
date_updated: 2020-07-14T12:45:50Z
file_id: '5288'
file_name: IST-2016-558-v1+1_inference_revised3101NB.pdf
file_size: 1554712
relation: main_file
- access_level: open_access
checksum: 2bceddb76edacd0cd5fad73051e2a928
content_type: application/pdf
creator: system
date_created: 2018-12-12T10:17:34Z
date_updated: 2020-07-14T12:45:50Z
file_id: '5289'
file_name: IST-2016-558-v1+2_inference_revised3101NBApp.pdf
file_size: 822964
relation: main_file
file_date_updated: 2020-07-14T12:45:50Z
has_accepted_license: '1'
intvolume: ' 87'
issue: '1'
language:
- iso: eng
month: '08'
oa: 1
oa_version: Submitted Version
page: 105 - 119
project:
- _id: 25B07788-B435-11E9-9278-68D0E5697425
call_identifier: FP7
grant_number: '250152'
name: Limits to selection in biology and in evolutionary computation
publication: Theoretical Population Biology
publication_status: published
publisher: Elsevier
publist_id: '3953'
pubrep_id: '558'
quality_controlled: '1'
scopus_import: 1
status: public
title: 'Inference in two dimensions: Allele frequencies versus lengths of shared sequence
blocks'
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 87
year: '2013'
...
---
_id: '2838'
abstract:
- lang: eng
text: Individuals with Down syndrome (DS) present important motor deficits that
derive from altered motor development of infants and young children. DYRK1A, a
candidate gene for DS abnormalities has been implicated in motor function due
to its expression in motor nuclei in the adult brain, and its overexpression in
DS mouse models leads to hyperactivity and altered motor learning. However, its
precise role in the adult motor system, or its possible involvement in postnatal
locomotor development has not yet been clarified. During the postnatal period
we observed time-specific expression of Dyrk1A in discrete subsets of brainstem
nuclei and spinal cord motor neurons. Interestingly, we describe for the first
time the presence of Dyrk1A in the presynaptic terminal of the neuromuscular junctions
and its axonal transport from the facial nucleus, suggesting a function for Dyrk1A
in these structures. Relevant to DS, Dyrk1A overexpression in transgenic mice
(TgDyrk1A) produces motor developmental alterations possibly contributing to DS
motor phenotypes and modifies the numbers of motor cholinergic neurons, suggesting
that the kinase may have a role in the development of the brainstem and spinal
cord motor system.
article_number: e54285
author:
- first_name: Gloria
full_name: Arquè Fuste, Gloria
id: 3CF33908-F248-11E8-B48F-1D18A9856A87
last_name: Arquè Fuste
- first_name: Anna
full_name: Casanovas, Anna
last_name: Casanovas
- first_name: Mara
full_name: Dierssen, Mara
last_name: Dierssen
citation:
ama: 'Arquè Fuste G, Casanovas A, Dierssen M. Dyrk1A is dynamically expressed on
subsets of motor neurons and in the neuromuscular junction: Possible role in Down
syndrome. PLoS One. 2013;8(1). doi:10.1371/journal.pone.0054285'
apa: 'Arquè Fuste, G., Casanovas, A., & Dierssen, M. (2013). Dyrk1A is dynamically
expressed on subsets of motor neurons and in the neuromuscular junction: Possible
role in Down syndrome. PLoS One. Public Library of Science. https://doi.org/10.1371/journal.pone.0054285'
chicago: 'Arquè Fuste, Gloria, Anna Casanovas, and Mara Dierssen. “Dyrk1A Is Dynamically
Expressed on Subsets of Motor Neurons and in the Neuromuscular Junction: Possible
Role in Down Syndrome.” PLoS One. Public Library of Science, 2013. https://doi.org/10.1371/journal.pone.0054285.'
ieee: 'G. Arquè Fuste, A. Casanovas, and M. Dierssen, “Dyrk1A is dynamically expressed
on subsets of motor neurons and in the neuromuscular junction: Possible role in
Down syndrome,” PLoS One, vol. 8, no. 1. Public Library of Science, 2013.'
ista: 'Arquè Fuste G, Casanovas A, Dierssen M. 2013. Dyrk1A is dynamically expressed
on subsets of motor neurons and in the neuromuscular junction: Possible role in
Down syndrome. PLoS One. 8(1), e54285.'
mla: 'Arquè Fuste, Gloria, et al. “Dyrk1A Is Dynamically Expressed on Subsets of
Motor Neurons and in the Neuromuscular Junction: Possible Role in Down Syndrome.”
PLoS One, vol. 8, no. 1, e54285, Public Library of Science, 2013, doi:10.1371/journal.pone.0054285.'
short: G. Arquè Fuste, A. Casanovas, M. Dierssen, PLoS One 8 (2013).
date_created: 2018-12-11T11:59:52Z
date_published: 2013-01-16T00:00:00Z
date_updated: 2021-01-12T07:00:07Z
day: '16'
ddc:
- '570'
department:
- _id: SiHi
doi: 10.1371/journal.pone.0054285
file:
- access_level: open_access
checksum: 512733b21419574a45f10cabef3d7f81
content_type: application/pdf
creator: system
date_created: 2018-12-12T10:15:38Z
date_updated: 2020-07-14T12:45:50Z
file_id: '5160'
file_name: IST-2016-407-v1+1_journal.pone.0054285.pdf
file_size: 4795977
relation: main_file
file_date_updated: 2020-07-14T12:45:50Z
has_accepted_license: '1'
intvolume: ' 8'
issue: '1'
language:
- iso: eng
month: '01'
oa: 1
oa_version: Published Version
publication: PLoS One
publication_status: published
publisher: Public Library of Science
publist_id: '3960'
pubrep_id: '407'
quality_controlled: '1'
scopus_import: 1
status: public
title: 'Dyrk1A is dynamically expressed on subsets of motor neurons and in the neuromuscular
junction: Possible role in Down syndrome'
tmp:
image: /images/cc_by.png
legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
short: CC BY (4.0)
type: journal_article
user_id: 3E5EF7F0-F248-11E8-B48F-1D18A9856A87
volume: 8
year: '2013'
...
---
_id: '2839'
abstract:
- lang: eng
text: Directional guidance of cells via gradients of chemokines is considered crucial
for embryonic development, cancer dissemination, and immune responses. Nevertheless,
the concept still lacks direct experimental confirmation in vivo. Here, we identify
endogenous gradients of the chemokine CCL21 within mouse skin and show that they
guide dendritic cells toward lymphatic vessels. Quantitative imaging reveals depots
of CCL21 within lymphatic endothelial cells and steeply decaying gradients within
the perilymphatic interstitium. These gradients match the migratory patterns of
the dendritic cells, which directionally approach vessels from a distance of up
to 90-micrometers. Interstitial CCL21 is immobilized to heparan sulfates, and
its experimental delocalization or swamping the endogenous gradients abolishes
directed migration. These findings functionally establish the concept of haptotaxis,
directed migration along immobilized gradients, in tissues.
acknowledgement: We thank M. Frank for technical assistance and S. Cremer, P. Schmalhorst,
and E. Kiermaier for critical reading of the manuscript. This work was supported
by a Humboldt Foundation postdoctoral fellowship (to M.W.), the German Research
Foundation (Si1323 1,2 to M.S.), the Human Frontier Science Program (HFSP RGP0058/2011
to M.S.), the European Research Council (ERC StG 281556 to M.S.), and the Swiss
National Science Foundation (31003A 127474 to D.F.L., 130488 to S.A.L.).
article_processing_charge: No
article_type: original
author:
- first_name: Michele
full_name: Weber, Michele
id: 3A3FC708-F248-11E8-B48F-1D18A9856A87
last_name: Weber
- first_name: Robert
full_name: Hauschild, Robert
id: 4E01D6B4-F248-11E8-B48F-1D18A9856A87
last_name: Hauschild
orcid: 0000-0001-9843-3522
- first_name: Jan
full_name: Schwarz, Jan
id: 346C1EC6-F248-11E8-B48F-1D18A9856A87
last_name: Schwarz
- first_name: Christine
full_name: Moussion, Christine
id: 3356F664-F248-11E8-B48F-1D18A9856A87
last_name: Moussion
- first_name: Ingrid
full_name: De Vries, Ingrid
id: 4C7D837E-F248-11E8-B48F-1D18A9856A87
last_name: De Vries
- first_name: Daniel
full_name: Legler, Daniel
last_name: Legler
- first_name: Sanjiv
full_name: Luther, Sanjiv
last_name: Luther
- first_name: Mark Tobias
full_name: Bollenbach, Mark Tobias
id: 3E6DB97A-F248-11E8-B48F-1D18A9856A87
last_name: Bollenbach
orcid: 0000-0003-4398-476X
- first_name: Michael K
full_name: Sixt, Michael K
id: 41E9FBEA-F248-11E8-B48F-1D18A9856A87
last_name: Sixt
orcid: 0000-0002-6620-9179
citation:
ama: Weber M, Hauschild R, Schwarz J, et al. Interstitial dendritic cell guidance
by haptotactic chemokine gradients. Science. 2013;339(6117):328-332. doi:10.1126/science.1228456
apa: Weber, M., Hauschild, R., Schwarz, J., Moussion, C., de Vries, I., Legler,
D., … Sixt, M. K. (2013). Interstitial dendritic cell guidance by haptotactic
chemokine gradients. Science. American Association for the Advancement
of Science. https://doi.org/10.1126/science.1228456
chicago: Weber, Michele, Robert Hauschild, Jan Schwarz, Christine Moussion, Ingrid
de Vries, Daniel Legler, Sanjiv Luther, Mark Tobias Bollenbach, and Michael K
Sixt. “Interstitial Dendritic Cell Guidance by Haptotactic Chemokine Gradients.”
Science. American Association for the Advancement of Science, 2013. https://doi.org/10.1126/science.1228456.
ieee: M. Weber et al., “Interstitial dendritic cell guidance by haptotactic
chemokine gradients,” Science, vol. 339, no. 6117. American Association
for the Advancement of Science, pp. 328–332, 2013.
ista: Weber M, Hauschild R, Schwarz J, Moussion C, de Vries I, Legler D, Luther
S, Bollenbach MT, Sixt MK. 2013. Interstitial dendritic cell guidance by haptotactic
chemokine gradients. Science. 339(6117), 328–332.
mla: Weber, Michele, et al. “Interstitial Dendritic Cell Guidance by Haptotactic
Chemokine Gradients.” Science, vol. 339, no. 6117, American Association
for the Advancement of Science, 2013, pp. 328–32, doi:10.1126/science.1228456.
short: M. Weber, R. Hauschild, J. Schwarz, C. Moussion, I. de Vries, D. Legler,
S. Luther, M.T. Bollenbach, M.K. Sixt, Science 339 (2013) 328–332.
date_created: 2018-12-11T11:59:52Z
date_published: 2013-01-18T00:00:00Z
date_updated: 2022-06-10T10:21:40Z
day: '18'
department:
- _id: MiSi
- _id: Bio
doi: 10.1126/science.1228456
ec_funded: 1
intvolume: ' 339'
issue: '6117'
language:
- iso: eng
main_file_link:
- open_access: '1'
url: https://kops.uni-konstanz.de/bitstream/123456789/26341/2/Weber_263418.pdf
month: '01'
oa: 1
oa_version: Published Version
page: 328 - 332
project:
- _id: 25A603A2-B435-11E9-9278-68D0E5697425
call_identifier: FP7
grant_number: '281556'
name: Cytoskeletal force generation and force transduction of migrating leukocytes
(EU)
- _id: 25ABD200-B435-11E9-9278-68D0E5697425
grant_number: RGP0058/2011
name: 'Cell migration in complex environments: from in vivo experiments to theoretical
models'
publication: Science
publication_status: published
publisher: American Association for the Advancement of Science
publist_id: '3959'
quality_controlled: '1'
scopus_import: '1'
status: public
title: Interstitial dendritic cell guidance by haptotactic chemokine gradients
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 339
year: '2013'
...
---
_id: '2837'
abstract:
- lang: eng
text: We consider a general class of N × N random matrices whose entries hij are
independent up to a symmetry constraint, but not necessarily identically distributed.
Our main result is a local semicircle law which improves previous results [17]
both in the bulk and at the edge. The error bounds are given in terms of the basic
small parameter of the model, maxi,j E|hij|2. As a consequence, we prove the universality
of the local n-point correlation functions in the bulk spectrum for a class of
matrices whose entries do not have comparable variances, including random band
matrices with band width W ≫N1-εn with some εn > 0 and with a negligible mean-field
component. In addition, we provide a coherent and pedagogical proof of the local
semicircle law, streamlining and strengthening previous arguments from [17, 19,
6].
author:
- first_name: László
full_name: Erdös, László
id: 4DBD5372-F248-11E8-B48F-1D18A9856A87
last_name: Erdös
orcid: 0000-0001-5366-9603
- first_name: Antti
full_name: Knowles, Antti
last_name: Knowles
- first_name: Horng
full_name: Yau, Horng
last_name: Yau
- first_name: Jun
full_name: Yin, Jun
last_name: Yin
citation:
ama: Erdös L, Knowles A, Yau H, Yin J. The local semicircle law for a general class
of random matrices. Electronic Journal of Probability. 2013;18(59):1-58.
doi:10.1214/EJP.v18-2473
apa: Erdös, L., Knowles, A., Yau, H., & Yin, J. (2013). The local semicircle
law for a general class of random matrices. Electronic Journal of Probability.
Institute of Mathematical Statistics. https://doi.org/10.1214/EJP.v18-2473
chicago: Erdös, László, Antti Knowles, Horng Yau, and Jun Yin. “The Local Semicircle
Law for a General Class of Random Matrices.” Electronic Journal of Probability.
Institute of Mathematical Statistics, 2013. https://doi.org/10.1214/EJP.v18-2473.
ieee: L. Erdös, A. Knowles, H. Yau, and J. Yin, “The local semicircle law for a
general class of random matrices,” Electronic Journal of Probability, vol.
18, no. 59. Institute of Mathematical Statistics, pp. 1–58, 2013.
ista: Erdös L, Knowles A, Yau H, Yin J. 2013. The local semicircle law for a general
class of random matrices. Electronic Journal of Probability. 18(59), 1–58.
mla: Erdös, László, et al. “The Local Semicircle Law for a General Class of Random
Matrices.” Electronic Journal of Probability, vol. 18, no. 59, Institute
of Mathematical Statistics, 2013, pp. 1–58, doi:10.1214/EJP.v18-2473.
short: L. Erdös, A. Knowles, H. Yau, J. Yin, Electronic Journal of Probability 18
(2013) 1–58.
date_created: 2018-12-11T11:59:51Z
date_published: 2013-05-29T00:00:00Z
date_updated: 2021-01-12T07:00:06Z
day: '29'
ddc:
- '530'
department:
- _id: LaEr
doi: 10.1214/EJP.v18-2473
file:
- access_level: open_access
checksum: aac9e52a00cb2f5149dc9e362b5ccf44
content_type: application/pdf
creator: system
date_created: 2018-12-12T10:15:46Z
date_updated: 2020-07-14T12:45:50Z
file_id: '5169'
file_name: IST-2016-406-v1+1_2473-13759-1-PB.pdf
file_size: 651497
relation: main_file
file_date_updated: 2020-07-14T12:45:50Z
has_accepted_license: '1'
intvolume: ' 18'
issue: '59'
language:
- iso: eng
month: '05'
oa: 1
oa_version: Published Version
page: 1-58
publication: Electronic Journal of Probability
publication_status: published
publisher: Institute of Mathematical Statistics
publist_id: '3962'
pubrep_id: '406'
quality_controlled: '1'
scopus_import: 1
status: public
title: The local semicircle law for a general class of random matrices
tmp:
image: /images/cc_by.png
legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
short: CC BY (4.0)
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 18
year: '2013'
...
---
_id: '2835'
abstract:
- lang: eng
text: The phytohormone auxin regulates virtually every aspect of plant development.
To identify new genes involved in auxin activity, a genetic screen was performed
for Arabidopsis (Arabidopsis thaliana) mutants with altered expression of the
auxin-responsive reporter DR5rev:GFP. One of the mutants recovered in the screen,
designated as weak auxin response3 (wxr3), exhibits much lower DR5rev:GFP expression
when treated with the synthetic auxin 2,4-dichlorophenoxyacetic acid and displays
severe defects in root development. The wxr3 mutant decreases polar auxin transport
and results in a disruption of the asymmetric auxin distribution. The levels of
the auxin transporters AUXIN1 and PIN-FORMED are dramatically reduced in the wxr3
root tip. Molecular analyses demonstrate that WXR3 is ROOT ULTRAVIOLET B-SENSITIVE1
(RUS1), a member of the conserved Domain of Unknown Function647 protein family
found in diverse eukaryotic organisms. Our data suggest that RUS1/WXR3 plays an
essential role in the regulation of polar auxin transport by maintaining the proper
level of auxin transporters on the plasma membrane.
author:
- first_name: Hong
full_name: Yu, Hong
last_name: Yu
- first_name: Michael
full_name: Karampelias, Michael
last_name: Karampelias
- first_name: Stéphanie
full_name: Robert, Stéphanie
last_name: Robert
- first_name: Wendy
full_name: Peer, Wendy
last_name: Peer
- first_name: Ranjan
full_name: Swarup, Ranjan
last_name: Swarup
- first_name: Songqing
full_name: Ye, Songqing
last_name: Ye
- first_name: Lei
full_name: Ge, Lei
last_name: Ge
- first_name: Jerry
full_name: Cohen, Jerry
last_name: Cohen
- first_name: Angus
full_name: Murphy, Angus
last_name: Murphy
- first_name: Jirí
full_name: Friml, Jirí
id: 4159519E-F248-11E8-B48F-1D18A9856A87
last_name: Friml
orcid: 0000-0002-8302-7596
- first_name: Mark
full_name: Estelle, Mark
last_name: Estelle
citation:
ama: Yu H, Karampelias M, Robert S, et al. Root ultraviolet b-sensitive1/weak auxin
response3 is essential for polar auxin transport in arabidopsis. Plant Physiology.
2013;162(2):965-976. doi:10.1104/pp.113.217018
apa: Yu, H., Karampelias, M., Robert, S., Peer, W., Swarup, R., Ye, S., … Estelle,
M. (2013). Root ultraviolet b-sensitive1/weak auxin response3 is essential for
polar auxin transport in arabidopsis. Plant Physiology. American Society
of Plant Biologists. https://doi.org/10.1104/pp.113.217018
chicago: Yu, Hong, Michael Karampelias, Stéphanie Robert, Wendy Peer, Ranjan Swarup,
Songqing Ye, Lei Ge, et al. “Root Ultraviolet B-Sensitive1/Weak Auxin Response3
Is Essential for Polar Auxin Transport in Arabidopsis.” Plant Physiology.
American Society of Plant Biologists, 2013. https://doi.org/10.1104/pp.113.217018.
ieee: H. Yu et al., “Root ultraviolet b-sensitive1/weak auxin response3 is
essential for polar auxin transport in arabidopsis,” Plant Physiology,
vol. 162, no. 2. American Society of Plant Biologists, pp. 965–976, 2013.
ista: Yu H, Karampelias M, Robert S, Peer W, Swarup R, Ye S, Ge L, Cohen J, Murphy
A, Friml J, Estelle M. 2013. Root ultraviolet b-sensitive1/weak auxin response3
is essential for polar auxin transport in arabidopsis. Plant Physiology. 162(2),
965–976.
mla: Yu, Hong, et al. “Root Ultraviolet B-Sensitive1/Weak Auxin Response3 Is Essential
for Polar Auxin Transport in Arabidopsis.” Plant Physiology, vol. 162,
no. 2, American Society of Plant Biologists, 2013, pp. 965–76, doi:10.1104/pp.113.217018.
short: H. Yu, M. Karampelias, S. Robert, W. Peer, R. Swarup, S. Ye, L. Ge, J. Cohen,
A. Murphy, J. Friml, M. Estelle, Plant Physiology 162 (2013) 965–976.
date_created: 2018-12-11T11:59:51Z
date_published: 2013-06-01T00:00:00Z
date_updated: 2021-01-12T07:00:05Z
day: '01'
department:
- _id: JiFr
doi: 10.1104/pp.113.217018
external_id:
pmid:
- '23580592'
intvolume: ' 162'
issue: '2'
language:
- iso: eng
main_file_link:
- open_access: '1'
url: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3668084/
month: '06'
oa: 1
oa_version: Submitted Version
page: 965 - 976
pmid: 1
publication: Plant Physiology
publication_status: published
publisher: American Society of Plant Biologists
publist_id: '3964'
quality_controlled: '1'
scopus_import: 1
status: public
title: Root ultraviolet b-sensitive1/weak auxin response3 is essential for polar auxin
transport in arabidopsis
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 162
year: '2013'
...
---
_id: '2836'
abstract:
- lang: eng
text: 'We study the automatic synthesis of fair non-repudiation protocols, a class
of fair exchange protocols, used for digital contract signing. First, we show
how to specify the objectives of the participating agents and the trusted third
party as path formulas in linear temporal logic and prove that the satisfaction
of these objectives imply fairness; a property required of fair exchange protocols.
We then show that weak (co-operative) co-synthesis and classical (strictly competitive)
co-synthesis fail, whereas assume-guarantee synthesis (AGS) succeeds. We demonstrate
the success of AGS as follows: (a) any solution of AGS is attack-free; no subset
of participants can violate the objectives of the other participants; (b) the
Asokan-Shoup-Waidner certified mail protocol that has known vulnerabilities is
not a solution of AGS; (c) the Kremer-Markowitch non-repudiation protocol is a
solution of AGS; and (d) AGS presents a new and symmetric fair non-repudiation
protocol that is attack-free. To our knowledge this is the first application of
synthesis to fair non-repudiation protocols, and our results show how synthesis
can both automatically discover vulnerabilities in protocols and generate correct
protocols. The solution to AGS can be computed efficiently as the secure equilibrium
solution of three-player graph games. '
author:
- first_name: Krishnendu
full_name: Chatterjee, Krishnendu
id: 2E5DCA20-F248-11E8-B48F-1D18A9856A87
last_name: Chatterjee
orcid: 0000-0002-4561-241X
- first_name: Vishwanath
full_name: Raman, Vishwanath
last_name: Raman
citation:
ama: Chatterjee K, Raman V. Assume-guarantee synthesis for digital contract signing.
Formal Aspects of Computing. 2013;26(4):825-859. doi:10.1007/s00165-013-0283-6
apa: Chatterjee, K., & Raman, V. (2013). Assume-guarantee synthesis for digital
contract signing. Formal Aspects of Computing. Springer. https://doi.org/10.1007/s00165-013-0283-6
chicago: Chatterjee, Krishnendu, and Vishwanath Raman. “Assume-Guarantee Synthesis
for Digital Contract Signing.” Formal Aspects of Computing. Springer, 2013.
https://doi.org/10.1007/s00165-013-0283-6.
ieee: K. Chatterjee and V. Raman, “Assume-guarantee synthesis for digital contract
signing,” Formal Aspects of Computing, vol. 26, no. 4. Springer, pp. 825–859,
2013.
ista: Chatterjee K, Raman V. 2013. Assume-guarantee synthesis for digital contract
signing. Formal Aspects of Computing. 26(4), 825–859.
mla: Chatterjee, Krishnendu, and Vishwanath Raman. “Assume-Guarantee Synthesis for
Digital Contract Signing.” Formal Aspects of Computing, vol. 26, no. 4,
Springer, 2013, pp. 825–59, doi:10.1007/s00165-013-0283-6.
short: K. Chatterjee, V. Raman, Formal Aspects of Computing 26 (2013) 825–859.
date_created: 2018-12-11T11:59:51Z
date_published: 2013-07-04T00:00:00Z
date_updated: 2021-01-12T07:00:06Z
day: '04'
department:
- _id: KrCh
doi: 10.1007/s00165-013-0283-6
ec_funded: 1
external_id:
arxiv:
- '1004.2697'
intvolume: ' 26'
issue: '4'
language:
- iso: eng
main_file_link:
- open_access: '1'
url: http://arxiv.org/abs/1004.2697
month: '07'
oa: 1
oa_version: Preprint
page: 825 - 859
project:
- _id: 2584A770-B435-11E9-9278-68D0E5697425
call_identifier: FWF
grant_number: P 23499-N23
name: Modern Graph Algorithmic Techniques in Formal Verification
- _id: 25863FF4-B435-11E9-9278-68D0E5697425
call_identifier: FWF
grant_number: S11407
name: Game Theory
- _id: 2581B60A-B435-11E9-9278-68D0E5697425
call_identifier: FP7
grant_number: '279307'
name: 'Quantitative Graph Games: Theory and Applications'
- _id: 2587B514-B435-11E9-9278-68D0E5697425
name: Microsoft Research Faculty Fellowship
publication: Formal Aspects of Computing
publication_status: published
publisher: Springer
publist_id: '3963'
quality_controlled: '1'
scopus_import: 1
status: public
title: Assume-guarantee synthesis for digital contract signing
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 26
year: '2013'
...
---
_id: '2840'
abstract:
- lang: eng
text: It is known that the entorhinal cortex plays a crucial role in spatial cognition
in rodents. Neuroanatomical and electrophysiological data suggest that there is
a functional distinction between 2 subregions within the entorhinal cortex, the
medial entorhinal cortex (MEC), and the lateral entorhinal cortex (LEC). Rats
with MEC or LEC lesions were trained in 2 navigation tasks requiring allothetic
(water maze task) or idiothetic (path integration) information processing and
2-object exploration tasks allowing testing of spatial and nonspatial processing
of intramaze objects. MEC lesions mildly affected place navigation in the water
maze and produced a path integration deficit. They also altered the processing
of spatial information in both exploration tasks while sparing the processing
of nonspatial information. LEC lesions did not affect navigation abilities in
both the water maze and the path integration tasks. They altered spatial and nonspatial
processing in the object exploration task but not in the one-trial recognition
task. Overall, these results indicate that the MEC is important for spatial processing
and path integration. The LEC has some influence on both spatial and nonspatial
processes, suggesting that the 2 kinds of information interact at the level of
the EC.
author:
- first_name: Tiffany
full_name: Van Cauter, Tiffany
last_name: Van Cauter
- first_name: Jeremy
full_name: Camon, Jeremy
last_name: Camon
- first_name: Alice
full_name: Alvernhe, Alice
id: 467FB3D4-F248-11E8-B48F-1D18A9856A87
last_name: Alvernhe
- first_name: Coralie
full_name: Elduayen, Coralie
last_name: Elduayen
- first_name: Francesca
full_name: Sargolini, Francesca
last_name: Sargolini
- first_name: Étienne
full_name: Save, Étienne
last_name: Save
citation:
ama: Van Cauter T, Camon J, Alvernhe A, Elduayen C, Sargolini F, Save É. Distinct
roles of medial and lateral entorhinal cortex in spatial cognition. Cerebral
Cortex. 2013;23(2):451-459. doi:10.1093/cercor/bhs033
apa: Van Cauter, T., Camon, J., Alvernhe, A., Elduayen, C., Sargolini, F., &
Save, É. (2013). Distinct roles of medial and lateral entorhinal cortex in spatial
cognition. Cerebral Cortex. Oxford University Press. https://doi.org/10.1093/cercor/bhs033
chicago: Van Cauter, Tiffany, Jeremy Camon, Alice Alvernhe, Coralie Elduayen, Francesca
Sargolini, and Étienne Save. “Distinct Roles of Medial and Lateral Entorhinal
Cortex in Spatial Cognition.” Cerebral Cortex. Oxford University Press,
2013. https://doi.org/10.1093/cercor/bhs033.
ieee: T. Van Cauter, J. Camon, A. Alvernhe, C. Elduayen, F. Sargolini, and É. Save,
“Distinct roles of medial and lateral entorhinal cortex in spatial cognition,”
Cerebral Cortex, vol. 23, no. 2. Oxford University Press, pp. 451–459,
2013.
ista: Van Cauter T, Camon J, Alvernhe A, Elduayen C, Sargolini F, Save É. 2013.
Distinct roles of medial and lateral entorhinal cortex in spatial cognition. Cerebral
Cortex. 23(2), 451–459.
mla: Van Cauter, Tiffany, et al. “Distinct Roles of Medial and Lateral Entorhinal
Cortex in Spatial Cognition.” Cerebral Cortex, vol. 23, no. 2, Oxford University
Press, 2013, pp. 451–59, doi:10.1093/cercor/bhs033.
short: T. Van Cauter, J. Camon, A. Alvernhe, C. Elduayen, F. Sargolini, É. Save,
Cerebral Cortex 23 (2013) 451–459.
date_created: 2018-12-11T11:59:52Z
date_published: 2013-02-01T00:00:00Z
date_updated: 2021-01-12T07:00:08Z
day: '01'
department:
- _id: JoCs
doi: 10.1093/cercor/bhs033
intvolume: ' 23'
issue: '2'
language:
- iso: eng
month: '02'
oa_version: None
page: 451 - 459
publication: Cerebral Cortex
publication_status: published
publisher: Oxford University Press
publist_id: '3958'
quality_controlled: '1'
scopus_import: 1
status: public
title: Distinct roles of medial and lateral entorhinal cortex in spatial cognition
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 23
year: '2013'
...
---
_id: '2841'
abstract:
- lang: eng
text: In zebrafish early development, blastoderm cells undergo extensive radial
intercalations, triggering the spreading of the blastoderm over the yolk cell
and thereby initiating embryonic body axis formation. Now reporting in Developmental
Cell, Song et al. (2013) demonstrate a critical function for EGF-dependent E-cadherin
endocytosis in promoting blastoderm cell intercalations.
author:
- first_name: Hitoshi
full_name: Morita, Hitoshi
id: 4C6E54C6-F248-11E8-B48F-1D18A9856A87
last_name: Morita
- first_name: Carl-Philipp J
full_name: Heisenberg, Carl-Philipp J
id: 39427864-F248-11E8-B48F-1D18A9856A87
last_name: Heisenberg
orcid: 0000-0002-0912-4566
citation:
ama: 'Morita H, Heisenberg C-PJ. Holding on and letting go: Cadherin turnover in
cell intercalation. Developmental Cell. 2013;24(6):567-569. doi:10.1016/j.devcel.2013.03.007'
apa: 'Morita, H., & Heisenberg, C.-P. J. (2013). Holding on and letting go:
Cadherin turnover in cell intercalation. Developmental Cell. Cell Press.
https://doi.org/10.1016/j.devcel.2013.03.007'
chicago: 'Morita, Hitoshi, and Carl-Philipp J Heisenberg. “Holding on and Letting
Go: Cadherin Turnover in Cell Intercalation.” Developmental Cell. Cell
Press, 2013. https://doi.org/10.1016/j.devcel.2013.03.007.'
ieee: 'H. Morita and C.-P. J. Heisenberg, “Holding on and letting go: Cadherin turnover
in cell intercalation,” Developmental Cell, vol. 24, no. 6. Cell Press,
pp. 567–569, 2013.'
ista: 'Morita H, Heisenberg C-PJ. 2013. Holding on and letting go: Cadherin turnover
in cell intercalation. Developmental Cell. 24(6), 567–569.'
mla: 'Morita, Hitoshi, and Carl-Philipp J. Heisenberg. “Holding on and Letting Go:
Cadherin Turnover in Cell Intercalation.” Developmental Cell, vol. 24,
no. 6, Cell Press, 2013, pp. 567–69, doi:10.1016/j.devcel.2013.03.007.'
short: H. Morita, C.-P.J. Heisenberg, Developmental Cell 24 (2013) 567–569.
date_created: 2018-12-11T11:59:52Z
date_published: 2013-05-25T00:00:00Z
date_updated: 2021-01-12T07:00:09Z
day: '25'
department:
- _id: CaHe
doi: 10.1016/j.devcel.2013.03.007
intvolume: ' 24'
issue: '6'
language:
- iso: eng
month: '05'
oa_version: None
page: 567 - 569
publication: Developmental Cell
publication_status: published
publisher: Cell Press
publist_id: '3956'
quality_controlled: '1'
scopus_import: 1
status: public
title: 'Holding on and letting go: Cadherin turnover in cell intercalation'
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 24
year: '2013'
...
---
_id: '2846'
abstract:
- lang: eng
text: The Red Queen hypothesis proposes that coevolving parasites select for outcrossing
in the host. Outcrossing relies on males, which often show lower immune investment
due to, for example, sexual selection. Here, we demonstrate that such sex differences
in immunity interfere with parasite-mediated selection for outcrossing. Two independent
coevolution experiments with Caenorhabditis elegans and its microparasite Bacillus
thuringiensis produced decreased yet stable frequencies of outcrossing male hosts.
A subsequent systematic analysis verified that male C. elegans suffered from a
direct selective disadvantage under parasite pressure (i.e. lower resistance,
decreased sexual activity, increased escape behaviour), which can reduce outcrossing
and thus male frequencies. At the same time, males offered an indirect selective
benefit, because male-mediated outcrossing increased offspring resistance, thus
favouring male persistence in the evolving populations. As sex differences in
immunity are widespread, such interference of opposing selective constraints is
likely of central importance during host adaptation to a coevolving parasite.
article_processing_charge: No
author:
- first_name: Leila
full_name: El Masri, Leila
id: 349A6E66-F248-11E8-B48F-1D18A9856A87
last_name: El Masri
- first_name: Rebecca
full_name: Schulte, Rebecca
last_name: Schulte
- first_name: Nadine
full_name: Timmermeyer, Nadine
last_name: Timmermeyer
- first_name: Stefanie
full_name: Thanisch, Stefanie
last_name: Thanisch
- first_name: Lena
full_name: Crummenerl, Lena
last_name: Crummenerl
- first_name: Gunther
full_name: Jansen, Gunther
last_name: Jansen
- first_name: Nico
full_name: Michiels, Nico
last_name: Michiels
- first_name: Hinrich
full_name: Schulenburg, Hinrich
last_name: Schulenburg
citation:
ama: El Masri L, Schulte R, Timmermeyer N, et al. Sex differences in host defence
interfere with parasite-mediated selection for outcrossing during host-parasite
coevolution. Ecology Letters. 2013;16(4):461-468. doi:10.1111/ele.12068
apa: El Masri, L., Schulte, R., Timmermeyer, N., Thanisch, S., Crummenerl, L., Jansen,
G., … Schulenburg, H. (2013). Sex differences in host defence interfere with parasite-mediated
selection for outcrossing during host-parasite coevolution. Ecology Letters.
Wiley-Blackwell. https://doi.org/10.1111/ele.12068
chicago: El Masri, Leila, Rebecca Schulte, Nadine Timmermeyer, Stefanie Thanisch,
Lena Crummenerl, Gunther Jansen, Nico Michiels, and Hinrich Schulenburg. “Sex
Differences in Host Defence Interfere with Parasite-Mediated Selection for Outcrossing
during Host-Parasite Coevolution.” Ecology Letters. Wiley-Blackwell, 2013.
https://doi.org/10.1111/ele.12068.
ieee: L. El Masri et al., “Sex differences in host defence interfere with
parasite-mediated selection for outcrossing during host-parasite coevolution,”
Ecology Letters, vol. 16, no. 4. Wiley-Blackwell, pp. 461–468, 2013.
ista: El Masri L, Schulte R, Timmermeyer N, Thanisch S, Crummenerl L, Jansen G,
Michiels N, Schulenburg H. 2013. Sex differences in host defence interfere with
parasite-mediated selection for outcrossing during host-parasite coevolution.
Ecology Letters. 16(4), 461–468.
mla: El Masri, Leila, et al. “Sex Differences in Host Defence Interfere with Parasite-Mediated
Selection for Outcrossing during Host-Parasite Coevolution.” Ecology Letters,
vol. 16, no. 4, Wiley-Blackwell, 2013, pp. 461–68, doi:10.1111/ele.12068.
short: L. El Masri, R. Schulte, N. Timmermeyer, S. Thanisch, L. Crummenerl, G. Jansen,
N. Michiels, H. Schulenburg, Ecology Letters 16 (2013) 461–468.
date_created: 2018-12-11T11:59:54Z
date_published: 2013-04-04T00:00:00Z
date_updated: 2022-08-25T14:51:57Z
day: '04'
ddc:
- '570'
doi: 10.1111/ele.12068
extern: '1'
file:
- access_level: open_access
checksum: aa7db788f7da7d7f102539a249ebce50
content_type: application/pdf
creator: system
date_created: 2018-12-12T10:15:52Z
date_updated: 2020-07-14T12:45:50Z
file_id: '5176'
file_name: IST-2016-404-v1+1_ele12068.pdf
file_size: 763731
relation: main_file
file_date_updated: 2020-07-14T12:45:50Z
has_accepted_license: '1'
intvolume: ' 16'
issue: '4'
language:
- iso: eng
month: '04'
oa: 1
oa_version: Published Version
page: 461 - 468
publication: Ecology Letters
publication_status: published
publisher: Wiley-Blackwell
publist_id: '3948'
pubrep_id: '404'
quality_controlled: '1'
scopus_import: '1'
status: public
title: Sex differences in host defence interfere with parasite-mediated selection
for outcrossing during host-parasite coevolution
tmp:
image: /images/cc_by.png
legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
short: CC BY (4.0)
type: journal_article
user_id: 3E5EF7F0-F248-11E8-B48F-1D18A9856A87
volume: 16
year: '2013'
...
---
_id: '2844'
abstract:
- lang: eng
text: As soon as a seed germinates, plant growth relates to gravity to ensure that
the root penetrates the soil and the shoot expands aerially. Whereas mechanisms
of positive and negative orthogravitropism of primary roots and shoots are relatively
well understood [1-3], lateral organs often show more complex growth behavior
[4]. Lateral roots (LRs) seemingly suppress positive gravitropic growth and show
a defined gravitropic set-point angle (GSA) that allows radial expansion of the
root system (plagiotropism) [3, 4]. Despite its eminent importance for root architecture,
it so far remains completely unknown how lateral organs partially suppress positive
orthogravitropism. Here we show that the phytohormone auxin steers GSA formation
and limits positive orthogravitropism in LR. Low and high auxin levels/signaling
lead to radial or axial root systems, respectively. At a cellular level, it is
the auxin transport-dependent regulation of asymmetric growth in the elongation
zone that determines GSA. Our data suggest that strong repression of PIN4/PIN7
and transient PIN3 expression limit auxin redistribution in young LR columella
cells. We conclude that PIN activity, by temporally limiting the asymmetric auxin
fluxes in the tip of LRs, induces transient, differential growth responses in
the elongation zone and, consequently, controls root architecture.
author:
- first_name: Michel
full_name: Rosquete, Michel
last_name: Rosquete
- first_name: Daniel
full_name: Von Wangenheim, Daniel
id: 49E91952-F248-11E8-B48F-1D18A9856A87
last_name: Von Wangenheim
orcid: 0000-0002-6862-1247
- first_name: Peter
full_name: Marhavy, Peter
id: 3F45B078-F248-11E8-B48F-1D18A9856A87
last_name: Marhavy
orcid: 0000-0001-5227-5741
- first_name: Elke
full_name: Barbez, Elke
last_name: Barbez
- first_name: Ernst
full_name: Stelzer, Ernst
last_name: Stelzer
- first_name: Eva
full_name: Benková, Eva
id: 38F4F166-F248-11E8-B48F-1D18A9856A87
last_name: Benková
orcid: 0000-0002-8510-9739
- first_name: Alexis
full_name: Maizel, Alexis
last_name: Maizel
- first_name: Jürgen
full_name: Kleine Vehn, Jürgen
last_name: Kleine Vehn
citation:
ama: Rosquete M, von Wangenheim D, Marhavý P, et al. An auxin transport mechanism
restricts positive orthogravitropism in lateral roots. Current Biology.
2013;23(9):817-822. doi:10.1016/j.cub.2013.03.064
apa: Rosquete, M., von Wangenheim, D., Marhavý, P., Barbez, E., Stelzer, E., Benková,
E., … Kleine Vehn, J. (2013). An auxin transport mechanism restricts positive
orthogravitropism in lateral roots. Current Biology. Cell Press. https://doi.org/10.1016/j.cub.2013.03.064
chicago: Rosquete, Michel, Daniel von Wangenheim, Peter Marhavý, Elke Barbez, Ernst
Stelzer, Eva Benková, Alexis Maizel, and Jürgen Kleine Vehn. “An Auxin Transport
Mechanism Restricts Positive Orthogravitropism in Lateral Roots.” Current Biology.
Cell Press, 2013. https://doi.org/10.1016/j.cub.2013.03.064.
ieee: M. Rosquete et al., “An auxin transport mechanism restricts positive
orthogravitropism in lateral roots,” Current Biology, vol. 23, no. 9. Cell
Press, pp. 817–822, 2013.
ista: Rosquete M, von Wangenheim D, Marhavý P, Barbez E, Stelzer E, Benková E, Maizel
A, Kleine Vehn J. 2013. An auxin transport mechanism restricts positive orthogravitropism
in lateral roots. Current Biology. 23(9), 817–822.
mla: Rosquete, Michel, et al. “An Auxin Transport Mechanism Restricts Positive Orthogravitropism
in Lateral Roots.” Current Biology, vol. 23, no. 9, Cell Press, 2013, pp.
817–22, doi:10.1016/j.cub.2013.03.064.
short: M. Rosquete, D. von Wangenheim, P. Marhavý, E. Barbez, E. Stelzer, E. Benková,
A. Maizel, J. Kleine Vehn, Current Biology 23 (2013) 817–822.
date_created: 2018-12-11T11:59:53Z
date_published: 2013-05-06T00:00:00Z
date_updated: 2021-01-12T07:00:10Z
day: '06'
department:
- _id: JiFr
- _id: EvBe
doi: 10.1016/j.cub.2013.03.064
ec_funded: 1
intvolume: ' 23'
issue: '9'
language:
- iso: eng
month: '05'
oa_version: None
page: 817 - 822
project:
- _id: 253FCA6A-B435-11E9-9278-68D0E5697425
call_identifier: FP7
grant_number: '207362'
name: Hormonal cross-talk in plant organogenesis
publication: Current Biology
publication_status: published
publisher: Cell Press
publist_id: '3950'
quality_controlled: '1'
scopus_import: 1
status: public
title: An auxin transport mechanism restricts positive orthogravitropism in lateral
roots
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 23
year: '2013'
...
---
_id: '2843'
abstract:
- lang: eng
text: 'Mathematical objects can be measured unambiguously, but not so objects from
our physical world. Even the total length of tubelike shapes has its difficulties.
We introduce a combination of geometric, probabilistic, and topological methods
to design a stable length estimate for tube-like shapes; that is: one that is
insensitive to small shape changes.'
alternative_title:
- LNCS
author:
- first_name: Herbert
full_name: Edelsbrunner, Herbert
id: 3FB178DA-F248-11E8-B48F-1D18A9856A87
last_name: Edelsbrunner
orcid: 0000-0002-9823-6833
- first_name: Florian
full_name: Pausinger, Florian
id: 2A77D7A2-F248-11E8-B48F-1D18A9856A87
last_name: Pausinger
orcid: 0000-0002-8379-3768
citation:
ama: 'Edelsbrunner H, Pausinger F. Stable length estimates of tube-like shapes.
In: 17th IAPR International Conference on Discrete Geometry for Computer Imagery.
Vol 7749. Springer; 2013:XV-XIX. doi:10.1007/978-3-642-37067-0'
apa: 'Edelsbrunner, H., & Pausinger, F. (2013). Stable length estimates of tube-like
shapes. In 17th IAPR International Conference on Discrete Geometry for Computer
Imagery (Vol. 7749, pp. XV–XIX). Seville, Spain: Springer. https://doi.org/10.1007/978-3-642-37067-0'
chicago: Edelsbrunner, Herbert, and Florian Pausinger. “Stable Length Estimates
of Tube-like Shapes.” In 17th IAPR International Conference on Discrete Geometry
for Computer Imagery, 7749:XV–XIX. Springer, 2013. https://doi.org/10.1007/978-3-642-37067-0.
ieee: H. Edelsbrunner and F. Pausinger, “Stable length estimates of tube-like shapes,”
in 17th IAPR International Conference on Discrete Geometry for Computer Imagery,
Seville, Spain, 2013, vol. 7749, pp. XV–XIX.
ista: 'Edelsbrunner H, Pausinger F. 2013. Stable length estimates of tube-like shapes.
17th IAPR International Conference on Discrete Geometry for Computer Imagery.
DGCI: Discrete Geometry for Computer Imagery, LNCS, vol. 7749, XV–XIX.'
mla: Edelsbrunner, Herbert, and Florian Pausinger. “Stable Length Estimates of Tube-like
Shapes.” 17th IAPR International Conference on Discrete Geometry for Computer
Imagery, vol. 7749, Springer, 2013, pp. XV–XIX, doi:10.1007/978-3-642-37067-0.
short: H. Edelsbrunner, F. Pausinger, in:, 17th IAPR International Conference on
Discrete Geometry for Computer Imagery, Springer, 2013, pp. XV–XIX.
conference:
end_date: 2013-03-22
location: Seville, Spain
name: 'DGCI: Discrete Geometry for Computer Imagery'
start_date: 2013-03-20
date_created: 2018-12-11T11:59:53Z
date_published: 2013-02-21T00:00:00Z
date_updated: 2023-02-23T10:35:00Z
day: '21'
department:
- _id: HeEd
doi: 10.1007/978-3-642-37067-0
intvolume: ' 7749'
language:
- iso: eng
month: '02'
oa_version: None
page: XV - XIX
publication: 17th IAPR International Conference on Discrete Geometry for Computer
Imagery
publication_status: published
publisher: Springer
publist_id: '3952'
quality_controlled: '1'
related_material:
record:
- id: '2255'
relation: later_version
status: public
scopus_import: 1
status: public
title: Stable length estimates of tube-like shapes
type: conference
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 7749
year: '2013'
...
---
_id: '2845'
abstract:
- lang: eng
text: At synapses formed between dissociated neurons, about half of all synaptic
vesicles are refractory to evoked release, forming the so-called "resting
pool." Here, we use optical measurements of vesicular pH to study developmental
changes in pool partitioning and vesicle cycling in cultured hippocampal slices.
Two-photon imaging of a genetically encoded two-color release sensor (ratio-sypHy)
allowed us to perform calibrated measurements at individual Schaffer collateral
boutons. Mature boutons released a large fraction of their vesicles during simulated
place field activity, and vesicle retrieval rates were 7-fold higher compared
to immature boutons. Saturating stimulation mobilized essentially all vesicles
at mature synapses. Resting pool formation and a concomitant reduction in evoked
release was induced by chronic depolarization but not by acute inhibition of the
protein phosphatase calcineurin. We conclude that synapses in CA1 undergo a prominent
refinement of vesicle use during early postnatal development that is not recapitulated
in dissociated neuronal culture.
author:
- first_name: Tobias
full_name: Rose, Tobias
last_name: Rose
- first_name: Philipp
full_name: Schönenberger, Philipp
id: 3B9D816C-F248-11E8-B48F-1D18A9856A87
last_name: Schönenberger
- first_name: Karel
full_name: Jezek, Karel
last_name: Jezek
- first_name: Thomas
full_name: Oertner, Thomas
last_name: Oertner
citation:
ama: Rose T, Schönenberger P, Jezek K, Oertner T. Developmental refinement of vesicle
cycling at Schaffer collateral synapses. Neuron. 2013;77(6):1109-1121.
doi:10.1016/j.neuron.2013.01.021
apa: Rose, T., Schönenberger, P., Jezek, K., & Oertner, T. (2013). Developmental
refinement of vesicle cycling at Schaffer collateral synapses. Neuron.
Elsevier. https://doi.org/10.1016/j.neuron.2013.01.021
chicago: Rose, Tobias, Philipp Schönenberger, Karel Jezek, and Thomas Oertner. “Developmental
Refinement of Vesicle Cycling at Schaffer Collateral Synapses.” Neuron.
Elsevier, 2013. https://doi.org/10.1016/j.neuron.2013.01.021.
ieee: T. Rose, P. Schönenberger, K. Jezek, and T. Oertner, “Developmental refinement
of vesicle cycling at Schaffer collateral synapses,” Neuron, vol. 77, no.
6. Elsevier, pp. 1109–1121, 2013.
ista: Rose T, Schönenberger P, Jezek K, Oertner T. 2013. Developmental refinement
of vesicle cycling at Schaffer collateral synapses. Neuron. 77(6), 1109–1121.
mla: Rose, Tobias, et al. “Developmental Refinement of Vesicle Cycling at Schaffer
Collateral Synapses.” Neuron, vol. 77, no. 6, Elsevier, 2013, pp. 1109–21,
doi:10.1016/j.neuron.2013.01.021.
short: T. Rose, P. Schönenberger, K. Jezek, T. Oertner, Neuron 77 (2013) 1109–1121.
date_created: 2018-12-11T11:59:54Z
date_published: 2013-03-20T00:00:00Z
date_updated: 2021-01-12T07:00:11Z
day: '20'
department:
- _id: JoCs
doi: 10.1016/j.neuron.2013.01.021
intvolume: ' 77'
issue: '6'
language:
- iso: eng
month: '03'
oa_version: None
page: 1109 - 1121
publication: Neuron
publication_status: published
publisher: Elsevier
publist_id: '3949'
quality_controlled: '1'
scopus_import: 1
status: public
title: Developmental refinement of vesicle cycling at Schaffer collateral synapses
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 77
year: '2013'
...
---
_id: '2854'
abstract:
- lang: eng
text: We consider concurrent games played on graphs. At every round of a game, each
player simultaneously and independently selects a move; the moves jointly determine
the transition to a successor state. Two basic objectives are the safety objective
to stay forever in a given set of states, and its dual, the reachability objective
to reach a given set of states. First, we present a simple proof of the fact that
in concurrent reachability games, for all ε>0, memoryless ε-optimal strategies
exist. A memoryless strategy is independent of the history of plays, and an ε-optimal
strategy achieves the objective with probability within ε of the value of the
game. In contrast to previous proofs of this fact, our proof is more elementary
and more combinatorial. Second, we present a strategy-improvement (a.k.a. policy-iteration)
algorithm for concurrent games with reachability objectives. Finally, we present
a strategy-improvement algorithm for turn-based stochastic games (where each player
selects moves in turns) with safety objectives. Our algorithms yield sequences
of player-1 strategies which ensure probabilities of winning that converge monotonically
(from below) to the value of the game. © 2012 Elsevier Inc.
acknowledgement: This work was partially supported in part by the NSF grants CCR-0132780,
CNS-0720884, CCR-0225610, by the Swiss National Science Foundation, ERC Start Grant
Graph Games (Project No. 279307), FWF NFN Grant S11407-N23 (RiSE), and a Microsoft
faculty fellows
article_processing_charge: No
article_type: original
author:
- first_name: Krishnendu
full_name: Chatterjee, Krishnendu
id: 2E5DCA20-F248-11E8-B48F-1D18A9856A87
last_name: Chatterjee
orcid: 0000-0002-4561-241X
- first_name: Luca
full_name: De Alfaro, Luca
last_name: De Alfaro
- first_name: Thomas A
full_name: Henzinger, Thomas A
id: 40876CD8-F248-11E8-B48F-1D18A9856A87
last_name: Henzinger
orcid: 0000−0002−2985−7724
citation:
ama: Chatterjee K, De Alfaro L, Henzinger TA. Strategy improvement for concurrent
reachability and turn based stochastic safety games. Journal of Computer and
System Sciences. 2013;79(5):640-657. doi:10.1016/j.jcss.2012.12.001
apa: Chatterjee, K., De Alfaro, L., & Henzinger, T. A. (2013). Strategy improvement
for concurrent reachability and turn based stochastic safety games. Journal
of Computer and System Sciences. Elsevier. https://doi.org/10.1016/j.jcss.2012.12.001
chicago: Chatterjee, Krishnendu, Luca De Alfaro, and Thomas A Henzinger. “Strategy
Improvement for Concurrent Reachability and Turn Based Stochastic Safety Games.”
Journal of Computer and System Sciences. Elsevier, 2013. https://doi.org/10.1016/j.jcss.2012.12.001.
ieee: K. Chatterjee, L. De Alfaro, and T. A. Henzinger, “Strategy improvement for
concurrent reachability and turn based stochastic safety games,” Journal of
Computer and System Sciences, vol. 79, no. 5. Elsevier, pp. 640–657, 2013.
ista: Chatterjee K, De Alfaro L, Henzinger TA. 2013. Strategy improvement for concurrent
reachability and turn based stochastic safety games. Journal of Computer and System
Sciences. 79(5), 640–657.
mla: Chatterjee, Krishnendu, et al. “Strategy Improvement for Concurrent Reachability
and Turn Based Stochastic Safety Games.” Journal of Computer and System Sciences,
vol. 79, no. 5, Elsevier, 2013, pp. 640–57, doi:10.1016/j.jcss.2012.12.001.
short: K. Chatterjee, L. De Alfaro, T.A. Henzinger, Journal of Computer and System
Sciences 79 (2013) 640–657.
date_created: 2018-12-11T11:59:57Z
date_published: 2013-08-01T00:00:00Z
date_updated: 2021-01-12T07:00:16Z
day: '01'
ddc:
- '000'
department:
- _id: KrCh
- _id: ToHe
doi: 10.1016/j.jcss.2012.12.001
ec_funded: 1
file:
- access_level: open_access
checksum: 6d3ee12cceb946a0abe69594b6a22409
content_type: application/pdf
creator: system
date_created: 2018-12-12T10:18:48Z
date_updated: 2020-07-14T12:45:51Z
file_id: '5370'
file_name: IST-2015-388-v1+1_1-s2.0-S0022000012001778-main.pdf
file_size: 425488
relation: main_file
file_date_updated: 2020-07-14T12:45:51Z
has_accepted_license: '1'
intvolume: ' 79'
issue: '5'
language:
- iso: eng
license: https://creativecommons.org/licenses/by-nc-nd/4.0/
month: '08'
oa: 1
oa_version: Published Version
page: 640 - 657
project:
- _id: 2581B60A-B435-11E9-9278-68D0E5697425
call_identifier: FP7
grant_number: '279307'
name: 'Quantitative Graph Games: Theory and Applications'
- _id: 25863FF4-B435-11E9-9278-68D0E5697425
call_identifier: FWF
grant_number: S11407
name: Game Theory
- _id: 2587B514-B435-11E9-9278-68D0E5697425
name: Microsoft Research Faculty Fellowship
publication: Journal of Computer and System Sciences
publication_status: published
publisher: Elsevier
publist_id: '3938'
pubrep_id: '388'
quality_controlled: '1'
scopus_import: 1
status: public
title: Strategy improvement for concurrent reachability and turn based stochastic
safety games
tmp:
image: /images/cc_by_nc_nd.png
legal_code_url: https://creativecommons.org/licenses/by-nc-nd/4.0/legalcode
name: Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International
(CC BY-NC-ND 4.0)
short: CC BY-NC-ND (4.0)
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 79
year: '2013'
...
---
_id: '2850'
abstract:
- lang: eng
text: "Recent work emphasizes that the maximum entropy principle provides a bridge
between statistical mechanics models for collective behavior in neural networks
and experiments on networks of real neurons. Most of this work has focused on
capturing the measured correlations among pairs of neurons. Here we suggest an
alternative, constructing models that are consistent with the distribution of
global network activity, i.e. the probability that K out of N cells in the network
generate action potentials in the same small time bin. The inverse problem that
we need to solve in constructing the model is analytically tractable, and provides
a natural 'thermodynamics' for the network in the limit of large N. We analyze
the responses of neurons in a small patch of the retina to naturalistic stimuli,
and find that the implied thermodynamics is very close to an unusual critical
point, in which the entropy (in proper units) is exactly equal to the energy.
© 2013 IOP Publishing Ltd and SISSA Medialab srl.\r\n"
acknowledgement: "his work was supported in part by NSF Grants IIS-0613435 and PHY-0957573,
by NIH Grants R01 EY14196 and P50 GM071508, by the Fannie and John Hertz Foundation,
by the Human Frontiers Science Program, by the Swartz Foundation, and by the WM
Keck Foundation.\r\n"
article_number: P03011
article_processing_charge: No
article_type: original
author:
- first_name: Gasper
full_name: Tkacik, Gasper
id: 3D494DCA-F248-11E8-B48F-1D18A9856A87
last_name: Tkacik
orcid: 0000-0002-6699-1455
- first_name: Olivier
full_name: Marre, Olivier
last_name: Marre
- first_name: Thierry
full_name: Mora, Thierry
last_name: Mora
- first_name: Dario
full_name: Amodei, Dario
last_name: Amodei
- first_name: Michael
full_name: Berry, Michael
last_name: Berry
- first_name: William
full_name: Bialek, William
last_name: Bialek
citation:
ama: Tkačik G, Marre O, Mora T, Amodei D, Berry M, Bialek W. The simplest maximum
entropy model for collective behavior in a neural network. Journal of Statistical
Mechanics Theory and Experiment. 2013;2013(3). doi:10.1088/1742-5468/2013/03/P03011
apa: Tkačik, G., Marre, O., Mora, T., Amodei, D., Berry, M., & Bialek, W. (2013).
The simplest maximum entropy model for collective behavior in a neural network.
Journal of Statistical Mechanics Theory and Experiment. IOP Publishing
Ltd. https://doi.org/10.1088/1742-5468/2013/03/P03011
chicago: Tkačik, Gašper, Olivier Marre, Thierry Mora, Dario Amodei, Michael Berry,
and William Bialek. “The Simplest Maximum Entropy Model for Collective Behavior
in a Neural Network.” Journal of Statistical Mechanics Theory and Experiment.
IOP Publishing Ltd., 2013. https://doi.org/10.1088/1742-5468/2013/03/P03011.
ieee: G. Tkačik, O. Marre, T. Mora, D. Amodei, M. Berry, and W. Bialek, “The simplest
maximum entropy model for collective behavior in a neural network,” Journal
of Statistical Mechanics Theory and Experiment, vol. 2013, no. 3. IOP Publishing
Ltd., 2013.
ista: Tkačik G, Marre O, Mora T, Amodei D, Berry M, Bialek W. 2013. The simplest
maximum entropy model for collective behavior in a neural network. Journal of
Statistical Mechanics Theory and Experiment. 2013(3), P03011.
mla: Tkačik, Gašper, et al. “The Simplest Maximum Entropy Model for Collective Behavior
in a Neural Network.” Journal of Statistical Mechanics Theory and Experiment,
vol. 2013, no. 3, P03011, IOP Publishing Ltd., 2013, doi:10.1088/1742-5468/2013/03/P03011.
short: G. Tkačik, O. Marre, T. Mora, D. Amodei, M. Berry, W. Bialek, Journal of
Statistical Mechanics Theory and Experiment 2013 (2013).
date_created: 2018-12-11T11:59:55Z
date_published: 2013-03-12T00:00:00Z
date_updated: 2021-01-12T07:00:14Z
day: '12'
department:
- _id: GaTk
doi: 10.1088/1742-5468/2013/03/P03011
external_id:
arxiv:
- '1207.6319'
intvolume: ' 2013'
issue: '3'
language:
- iso: eng
main_file_link:
- open_access: '1'
url: http://arxiv.org/abs/1207.6319
month: '03'
oa: 1
oa_version: Preprint
publication: Journal of Statistical Mechanics Theory and Experiment
publication_status: published
publisher: IOP Publishing Ltd.
publist_id: '3942'
quality_controlled: '1'
scopus_import: 1
status: public
title: The simplest maximum entropy model for collective behavior in a neural network
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 2013
year: '2013'
...
---
_id: '2851'
abstract:
- lang: eng
text: The number of possible activity patterns in a population of neurons grows
exponentially with the size of the population. Typical experiments explore only
a tiny fraction of the large space of possible activity patterns in the case of
populations with more than 10 or 20 neurons. It is thus impossible, in this undersampled
regime, to estimate the probabilities with which most of the activity patterns
occur. As a result, the corresponding entropy - which is a measure of the computational
power of the neural population - cannot be estimated directly. We propose a simple
scheme for estimating the entropy in the undersampled regime, which bounds its
value from both below and above. The lower bound is the usual 'naive' entropy
of the experimental frequencies. The upper bound results from a hybrid approximation
of the entropy which makes use of the naive estimate, a maximum entropy fit, and
a coverage adjustment. We apply our simple scheme to artificial data, in order
to check their accuracy; we also compare its performance to those of several previously
defined entropy estimators. We then apply it to actual measurements of neural
activity in populations with up to 100 cells. Finally, we discuss the similarities
and differences between the proposed simple estimation scheme and various earlier
methods. © 2013 IOP Publishing Ltd and SISSA Medialab srl.
article_number: P03015
author:
- first_name: Michael
full_name: Berry, Michael
last_name: Berry
- first_name: Gasper
full_name: Tkacik, Gasper
id: 3D494DCA-F248-11E8-B48F-1D18A9856A87
last_name: Tkacik
orcid: 0000-0002-6699-1455
- first_name: Julien
full_name: Dubuis, Julien
last_name: Dubuis
- first_name: Olivier
full_name: Marre, Olivier
last_name: Marre
- first_name: Ravá
full_name: Da Silveira, Ravá
last_name: Da Silveira
citation:
ama: Berry M, Tkačik G, Dubuis J, Marre O, Da Silveira R. A simple method for estimating
the entropy of neural activity. Journal of Statistical Mechanics Theory and
Experiment. 2013;2013(3). doi:10.1088/1742-5468/2013/03/P03015
apa: Berry, M., Tkačik, G., Dubuis, J., Marre, O., & Da Silveira, R. (2013).
A simple method for estimating the entropy of neural activity. Journal of Statistical
Mechanics Theory and Experiment. IOP Publishing Ltd. https://doi.org/10.1088/1742-5468/2013/03/P03015
chicago: Berry, Michael, Gašper Tkačik, Julien Dubuis, Olivier Marre, and Ravá Da
Silveira. “A Simple Method for Estimating the Entropy of Neural Activity.” Journal
of Statistical Mechanics Theory and Experiment. IOP Publishing Ltd., 2013.
https://doi.org/10.1088/1742-5468/2013/03/P03015.
ieee: M. Berry, G. Tkačik, J. Dubuis, O. Marre, and R. Da Silveira, “A simple method
for estimating the entropy of neural activity,” Journal of Statistical Mechanics
Theory and Experiment, vol. 2013, no. 3. IOP Publishing Ltd., 2013.
ista: Berry M, Tkačik G, Dubuis J, Marre O, Da Silveira R. 2013. A simple method
for estimating the entropy of neural activity. Journal of Statistical Mechanics
Theory and Experiment. 2013(3), P03015.
mla: Berry, Michael, et al. “A Simple Method for Estimating the Entropy of Neural
Activity.” Journal of Statistical Mechanics Theory and Experiment, vol.
2013, no. 3, P03015, IOP Publishing Ltd., 2013, doi:10.1088/1742-5468/2013/03/P03015.
short: M. Berry, G. Tkačik, J. Dubuis, O. Marre, R. Da Silveira, Journal of Statistical
Mechanics Theory and Experiment 2013 (2013).
date_created: 2018-12-11T11:59:56Z
date_published: 2013-03-12T00:00:00Z
date_updated: 2021-01-12T07:00:14Z
day: '12'
department:
- _id: GaTk
doi: 10.1088/1742-5468/2013/03/P03015
intvolume: ' 2013'
issue: '3'
language:
- iso: eng
month: '03'
oa_version: None
publication: Journal of Statistical Mechanics Theory and Experiment
publication_status: published
publisher: IOP Publishing Ltd.
publist_id: '3941'
quality_controlled: '1'
scopus_import: 1
status: public
title: A simple method for estimating the entropy of neural activity
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 2013
year: '2013'
...
---
_id: '2857'
abstract:
- lang: eng
text: In the vibrant field of optogenetics, optics and genetic targeting are combined
to commandeer cellular functions, such as the neuronal action potential, by optically
stimulating light-sensitive ion channels expressed in the cell membrane. One broadly
applicable manifestation of this approach are covalently attached photochromic
tethered ligands (PTLs) that allow activating ligand-gated ion channels with outstanding
spatial and temporal resolution. Here, we describe all steps towards the successful
development and application of PTL-gated ion channels in cell lines and primary
cells. The basis for these experiments forms a combination of molecular modeling,
genetic engineering, cell culture, and electrophysiology. The light-gated glutamate
receptor (LiGluR), which consists of the PTL-functionalized GluK2 receptor, serves
as a model.
alternative_title:
- MIMB
author:
- first_name: Stephanie
full_name: Szobota, Stephanie
last_name: Szobota
- first_name: Catherine
full_name: Mckenzie, Catherine
id: 3EEDE19A-F248-11E8-B48F-1D18A9856A87
last_name: Mckenzie
- first_name: Harald L
full_name: Janovjak, Harald L
id: 33BA6C30-F248-11E8-B48F-1D18A9856A87
last_name: Janovjak
orcid: 0000-0002-8023-9315
citation:
ama: Szobota S, Mckenzie C, Janovjak HL. Optical control of ligand-gated ion channels.
Methods in Molecular Biology. 2013;998:417-435. doi:10.1007/978-1-62703-351-0_32
apa: Szobota, S., Mckenzie, C., & Janovjak, H. L. (2013). Optical control of
ligand-gated ion channels. Methods in Molecular Biology. Springer. https://doi.org/10.1007/978-1-62703-351-0_32
chicago: Szobota, Stephanie, Catherine Mckenzie, and Harald L Janovjak. “Optical
Control of Ligand-Gated Ion Channels.” Methods in Molecular Biology. Springer,
2013. https://doi.org/10.1007/978-1-62703-351-0_32.
ieee: S. Szobota, C. Mckenzie, and H. L. Janovjak, “Optical control of ligand-gated
ion channels,” Methods in Molecular Biology, vol. 998. Springer, pp. 417–435,
2013.
ista: Szobota S, Mckenzie C, Janovjak HL. 2013. Optical control of ligand-gated
ion channels. Methods in Molecular Biology. 998, 417–435.
mla: Szobota, Stephanie, et al. “Optical Control of Ligand-Gated Ion Channels.”
Methods in Molecular Biology, vol. 998, Springer, 2013, pp. 417–35, doi:10.1007/978-1-62703-351-0_32.
short: S. Szobota, C. Mckenzie, H.L. Janovjak, Methods in Molecular Biology 998
(2013) 417–435.
date_created: 2018-12-11T11:59:57Z
date_published: 2013-02-22T00:00:00Z
date_updated: 2021-01-12T07:00:17Z
day: '22'
ddc:
- '570'
department:
- _id: HaJa
doi: 10.1007/978-1-62703-351-0_32
ec_funded: 1
file:
- access_level: open_access
checksum: 1701f0d989f27ddac471b19a894ec0d1
content_type: application/pdf
creator: system
date_created: 2018-12-12T10:12:34Z
date_updated: 2020-07-14T12:45:51Z
file_id: '4952'
file_name: IST-2017-834-v1+1_szobota.pdf
file_size: 336734
relation: main_file
file_date_updated: 2020-07-14T12:45:51Z
has_accepted_license: '1'
intvolume: ' 998'
language:
- iso: eng
month: '02'
oa: 1
oa_version: Submitted Version
page: 417 - 435
project:
- _id: 255BFFFA-B435-11E9-9278-68D0E5697425
grant_number: RGY0084/2012
name: In situ real-time imaging of neurotransmitter signaling using designer optical
sensors (HFSP Young Investigator)
- _id: 25548C20-B435-11E9-9278-68D0E5697425
call_identifier: FP7
grant_number: '303564'
name: Microbial Ion Channels for Synthetic Neurobiology
publication: Methods in Molecular Biology
publication_status: published
publisher: Springer
publist_id: '3932'
pubrep_id: '834'
quality_controlled: '1'
scopus_import: 1
status: public
title: Optical control of ligand-gated ion channels
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 998
year: '2013'
...
---
_id: '2860'
abstract:
- lang: eng
text: 'In the hippocampus, cell assemblies forming mnemonic representations of space
are thought to arise as a result of changes in functional connections of pyramidal
cells. We have found that CA1 interneuron circuits are also reconfigured during
goal-oriented spatial learning through modification of inputs from pyramidal cells.
As learning progressed, new pyramidal assemblies expressed in theta cycles alternated
with previously established ones, and eventually overtook them. The firing patterns
of interneurons developed a relationship to new, learning-related assemblies:
some interneurons associated their activity with new pyramidal assemblies while
some others dissociated from them. These firing associations were explained by
changes in the weight of monosynaptic inputs received by interneurons from new
pyramidal assemblies, as these predicted the associational changes. Spatial learning
thus engages circuit modifications in the hippocampus that incorporate a redistribution
of inhibitory activity that might assist in the segregation of competing pyramidal
cell assembly patterns in space and time.'
acknowledgement: D.D. and J.C. were supported by a MRC Intramural Programme Grant
U138197111
author:
- first_name: David
full_name: Dupret, David
last_name: Dupret
- first_name: Joseph
full_name: O'Neill, Joseph
id: 426376DC-F248-11E8-B48F-1D18A9856A87
last_name: O'Neill
- first_name: Jozsef L
full_name: Csicsvari, Jozsef L
id: 3FA14672-F248-11E8-B48F-1D18A9856A87
last_name: Csicsvari
orcid: 0000-0002-5193-4036
citation:
ama: Dupret D, O’Neill J, Csicsvari JL. Dynamic reconfiguration of hippocampal interneuron
circuits during spatial learning. Neuron. 2013;78(1):166-180. doi:10.1016/j.neuron.2013.01.033
apa: Dupret, D., O’Neill, J., & Csicsvari, J. L. (2013). Dynamic reconfiguration
of hippocampal interneuron circuits during spatial learning. Neuron. Elsevier.
https://doi.org/10.1016/j.neuron.2013.01.033
chicago: Dupret, David, Joseph O’Neill, and Jozsef L Csicsvari. “Dynamic Reconfiguration
of Hippocampal Interneuron Circuits during Spatial Learning.” Neuron. Elsevier,
2013. https://doi.org/10.1016/j.neuron.2013.01.033.
ieee: D. Dupret, J. O’Neill, and J. L. Csicsvari, “Dynamic reconfiguration of hippocampal
interneuron circuits during spatial learning,” Neuron, vol. 78, no. 1.
Elsevier, pp. 166–180, 2013.
ista: Dupret D, O’Neill J, Csicsvari JL. 2013. Dynamic reconfiguration of hippocampal
interneuron circuits during spatial learning. Neuron. 78(1), 166–180.
mla: Dupret, David, et al. “Dynamic Reconfiguration of Hippocampal Interneuron Circuits
during Spatial Learning.” Neuron, vol. 78, no. 1, Elsevier, 2013, pp. 166–80,
doi:10.1016/j.neuron.2013.01.033.
short: D. Dupret, J. O’Neill, J.L. Csicsvari, Neuron 78 (2013) 166–180.
date_created: 2018-12-11T11:59:59Z
date_published: 2013-03-21T00:00:00Z
date_updated: 2021-01-12T07:00:19Z
day: '21'
ddc:
- '570'
department:
- _id: JoCs
doi: 10.1016/j.neuron.2013.01.033
ec_funded: 1
file:
- access_level: open_access
checksum: 0e18cb8561153ddb50bb5af16e7c9e97
content_type: application/pdf
creator: dernst
date_created: 2019-01-23T08:08:07Z
date_updated: 2020-07-14T12:45:52Z
file_id: '5877'
file_name: 2013_Neuron_Dupret.pdf
file_size: 2637837
relation: main_file
file_date_updated: 2020-07-14T12:45:52Z
has_accepted_license: '1'
intvolume: ' 78'
issue: '1'
language:
- iso: eng
month: '03'
oa: 1
oa_version: Published Version
page: 166 - 180
project:
- _id: 257A4776-B435-11E9-9278-68D0E5697425
call_identifier: FP7
grant_number: '281511'
name: Memory-related information processing in neuronal circuits of the hippocampus
and entorhinal cortex
publication: Neuron
publication_status: published
publisher: Elsevier
publist_id: '3929'
quality_controlled: '1'
scopus_import: 1
status: public
title: Dynamic reconfiguration of hippocampal interneuron circuits during spatial
learning
tmp:
image: /images/cc_by.png
legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
short: CC BY (4.0)
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 78
year: '2013'
...
---
_id: '2855'
abstract:
- lang: eng
text: Genomic imprinting leads to preferred expression of either the maternal or
paternal alleles of a subset of genes. Imprinting is essential for mammalian development,
and its deregulation causes many diseases. However, the functional relevance of
imprinting at the cellular level is poorly understood for most imprinted genes.
We used mosaic analysis with double markers (MADM) in mice to create uniparental
disomies (UPDs) and to visualize imprinting effects with single-cell resolution.
Although chromosome 12 UPD did not produce detectable phenotypes, chromosome 7
UPD caused highly significant paternal growth dominance in the liver and lung,
but not in the brain or heart. A single gene on chromosome 7, encoding the secreted
insulin-like growth factor 2 (IGF2), accounts for most of the paternal dominance
effect. Mosaic analyses implied additional imprinted loci on chromosome 7 acting
cell autonomously to transmit the IGF2 signal. Our study reveals chromosome- and
cell-type specificity of genomic imprinting effects.
author:
- first_name: Simon
full_name: Hippenmeyer, Simon
id: 37B36620-F248-11E8-B48F-1D18A9856A87
last_name: Hippenmeyer
orcid: 0000-0003-2279-1061
- first_name: Randy
full_name: Johnson, Randy
last_name: Johnson
- first_name: Liqun
full_name: Luo, Liqun
last_name: Luo
citation:
ama: Hippenmeyer S, Johnson R, Luo L. Mosaic analysis with double markers reveals
cell type specific paternal growth dominance. Cell Reports. 2013;3(3):960-967.
doi:10.1016/j.celrep.2013.02.002
apa: Hippenmeyer, S., Johnson, R., & Luo, L. (2013). Mosaic analysis with double
markers reveals cell type specific paternal growth dominance. Cell Reports.
Cell Press. https://doi.org/10.1016/j.celrep.2013.02.002
chicago: Hippenmeyer, Simon, Randy Johnson, and Liqun Luo. “Mosaic Analysis with
Double Markers Reveals Cell Type Specific Paternal Growth Dominance.” Cell
Reports. Cell Press, 2013. https://doi.org/10.1016/j.celrep.2013.02.002.
ieee: S. Hippenmeyer, R. Johnson, and L. Luo, “Mosaic analysis with double markers
reveals cell type specific paternal growth dominance,” Cell Reports, vol.
3, no. 3. Cell Press, pp. 960–967, 2013.
ista: Hippenmeyer S, Johnson R, Luo L. 2013. Mosaic analysis with double markers
reveals cell type specific paternal growth dominance. Cell Reports. 3(3), 960–967.
mla: Hippenmeyer, Simon, et al. “Mosaic Analysis with Double Markers Reveals Cell
Type Specific Paternal Growth Dominance.” Cell Reports, vol. 3, no. 3,
Cell Press, 2013, pp. 960–67, doi:10.1016/j.celrep.2013.02.002.
short: S. Hippenmeyer, R. Johnson, L. Luo, Cell Reports 3 (2013) 960–967.
date_created: 2018-12-11T11:59:57Z
date_published: 2013-03-28T00:00:00Z
date_updated: 2021-01-12T07:00:16Z
day: '28'
ddc:
- '570'
department:
- _id: SiHi
doi: 10.1016/j.celrep.2013.02.002
file:
- access_level: open_access
checksum: 6e977b918e81384cd571ec5a9d812289
content_type: application/pdf
creator: system
date_created: 2018-12-12T10:17:20Z
date_updated: 2020-07-14T12:45:51Z
file_id: '5274'
file_name: IST-2016-405-v1+1_1-s2.0-S2211124713000612-main.pdf
file_size: 1907211
relation: main_file
file_date_updated: 2020-07-14T12:45:51Z
has_accepted_license: '1'
intvolume: ' 3'
issue: '3'
language:
- iso: eng
month: '03'
oa: 1
oa_version: Published Version
page: 960 - 967
publication: Cell Reports
publication_status: published
publisher: Cell Press
publist_id: '3937'
pubrep_id: '405'
quality_controlled: '1'
scopus_import: 1
status: public
title: Mosaic analysis with double markers reveals cell type specific paternal growth
dominance
tmp:
image: /images/cc_by_nc_nd.png
legal_code_url: https://creativecommons.org/licenses/by-nc-nd/4.0/legalcode
name: Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International
(CC BY-NC-ND 4.0)
short: CC BY-NC-ND (4.0)
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 3
year: '2013'
...
---
_id: '2856'
abstract:
- lang: eng
text: 'G protein–coupled receptors (GPCRs), the largest family of membrane signaling
proteins, respond to neurotransmitters, hormones and small environmental molecules.
The neuronal function of many GPCRs has been difficult to resolve because of an
inability to gate them with subtype specificity, spatial precision, speed and
reversibility. To address this, we developed an approach for opto-chemical engineering
of native GPCRs. We applied this to the metabotropic glutamate receptors (mGluRs)
to generate light-agonized and light-antagonized mGluRs (LimGluRs). The light-agonized
LimGluR2, on which we focused, was fast, bistable and supported multiple rounds
of on/off switching. Light gated two of the primary neuronal functions of mGluR2:
suppression of excitability and inhibition of neurotransmitter release. We found
that the light-antagonized tool LimGluR2-block was able to manipulate negative
feedback of synaptically released glutamate on transmitter release. We generalized
the optical control to two additional family members: mGluR3 and mGluR6. This
system worked in rodent brain slices and in zebrafish in vivo, where we found
that mGluR2 modulated the threshold for escape behavior. These light-gated mGluRs
pave the way for determining the roles of mGluRs in synaptic plasticity, memory
and disease.'
acknowledgement: National Science Foundation grants CHE-0233882 and CHE-0840505 (to
the College of Chemistry at the University of California, Berkeley), a postdoctoral
fellowship of the European Molecular Biology Organization (H.J.)
author:
- first_name: Joshua
full_name: Levitz, Joshua
last_name: Levitz
- first_name: Carlos
full_name: Pantoja, Carlos
last_name: Pantoja
- first_name: Benjamin
full_name: Gaub, Benjamin
last_name: Gaub
- first_name: Harald L
full_name: Janovjak, Harald L
id: 33BA6C30-F248-11E8-B48F-1D18A9856A87
last_name: Janovjak
orcid: 0000-0002-8023-9315
- first_name: Andreas
full_name: Reiner, Andreas
last_name: Reiner
- first_name: Adam
full_name: Hoagland, Adam
last_name: Hoagland
- first_name: David
full_name: Schoppik, David
last_name: Schoppik
- first_name: Brian
full_name: Kane, Brian
last_name: Kane
- first_name: Philipp
full_name: Stawski, Philipp
last_name: Stawski
- first_name: Alexander
full_name: Schier, Alexander
last_name: Schier
- first_name: Dirk
full_name: Trauner, Dirk
last_name: Trauner
- first_name: Ehud
full_name: Isacoff, Ehud
last_name: Isacoff
citation:
ama: Levitz J, Pantoja C, Gaub B, et al. Optical control of metabotropic glutamate
receptors. Nature Neuroscience. 2013;16:507-516. doi:10.1038/nn.3346
apa: Levitz, J., Pantoja, C., Gaub, B., Janovjak, H. L., Reiner, A., Hoagland, A.,
… Isacoff, E. (2013). Optical control of metabotropic glutamate receptors. Nature
Neuroscience. Nature Publishing Group. https://doi.org/10.1038/nn.3346
chicago: Levitz, Joshua, Carlos Pantoja, Benjamin Gaub, Harald L Janovjak, Andreas
Reiner, Adam Hoagland, David Schoppik, et al. “Optical Control of Metabotropic
Glutamate Receptors.” Nature Neuroscience. Nature Publishing Group, 2013.
https://doi.org/10.1038/nn.3346.
ieee: J. Levitz et al., “Optical control of metabotropic glutamate receptors,”
Nature Neuroscience, vol. 16. Nature Publishing Group, pp. 507–516, 2013.
ista: Levitz J, Pantoja C, Gaub B, Janovjak HL, Reiner A, Hoagland A, Schoppik D,
Kane B, Stawski P, Schier A, Trauner D, Isacoff E. 2013. Optical control of metabotropic
glutamate receptors. Nature Neuroscience. 16, 507–516.
mla: Levitz, Joshua, et al. “Optical Control of Metabotropic Glutamate Receptors.”
Nature Neuroscience, vol. 16, Nature Publishing Group, 2013, pp. 507–16,
doi:10.1038/nn.3346.
short: J. Levitz, C. Pantoja, B. Gaub, H.L. Janovjak, A. Reiner, A. Hoagland, D.
Schoppik, B. Kane, P. Stawski, A. Schier, D. Trauner, E. Isacoff, Nature Neuroscience
16 (2013) 507–516.
date_created: 2018-12-11T11:59:57Z
date_published: 2013-03-03T00:00:00Z
date_updated: 2021-01-12T07:00:16Z
day: '03'
department:
- _id: HaJa
doi: 10.1038/nn.3346
external_id:
pmid:
- '23455609'
intvolume: ' 16'
language:
- iso: eng
main_file_link:
- open_access: '1'
url: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3681425/
month: '03'
oa: 1
oa_version: Submitted Version
page: 507 - 516
pmid: 1
publication: Nature Neuroscience
publication_status: published
publisher: Nature Publishing Group
publist_id: '3936'
quality_controlled: '1'
scopus_import: 1
status: public
title: Optical control of metabotropic glutamate receptors
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 16
year: '2013'
...
---
_id: '2859'
abstract:
- lang: eng
text: Given a continuous function f:X-R on a topological space, we consider the
preimages of intervals and their homology groups and show how to read the ranks
of these groups from the extended persistence diagram of f. In addition, we quantify
the robustness of the homology classes under perturbations of f using well groups,
and we show how to read the ranks of these groups from the same extended persistence
diagram. The special case X=R3 has ramifications in the fields of medical imaging
and scientific visualization.
author:
- first_name: Paul
full_name: Bendich, Paul
id: 43F6EC54-F248-11E8-B48F-1D18A9856A87
last_name: Bendich
- first_name: Herbert
full_name: Edelsbrunner, Herbert
id: 3FB178DA-F248-11E8-B48F-1D18A9856A87
last_name: Edelsbrunner
orcid: 0000-0002-9823-6833
- first_name: Dmitriy
full_name: Morozov, Dmitriy
last_name: Morozov
- first_name: Amit
full_name: Patel, Amit
id: 34A254A0-F248-11E8-B48F-1D18A9856A87
last_name: Patel
citation:
ama: Bendich P, Edelsbrunner H, Morozov D, Patel A. Homology and robustness of level
and interlevel sets. Homology, Homotopy and Applications. 2013;15(1):51-72.
doi:10.4310/HHA.2013.v15.n1.a3
apa: Bendich, P., Edelsbrunner, H., Morozov, D., & Patel, A. (2013). Homology
and robustness of level and interlevel sets. Homology, Homotopy and Applications.
International Press. https://doi.org/10.4310/HHA.2013.v15.n1.a3
chicago: Bendich, Paul, Herbert Edelsbrunner, Dmitriy Morozov, and Amit Patel. “Homology
and Robustness of Level and Interlevel Sets.” Homology, Homotopy and Applications.
International Press, 2013. https://doi.org/10.4310/HHA.2013.v15.n1.a3.
ieee: P. Bendich, H. Edelsbrunner, D. Morozov, and A. Patel, “Homology and robustness
of level and interlevel sets,” Homology, Homotopy and Applications, vol.
15, no. 1. International Press, pp. 51–72, 2013.
ista: Bendich P, Edelsbrunner H, Morozov D, Patel A. 2013. Homology and robustness
of level and interlevel sets. Homology, Homotopy and Applications. 15(1), 51–72.
mla: Bendich, Paul, et al. “Homology and Robustness of Level and Interlevel Sets.”
Homology, Homotopy and Applications, vol. 15, no. 1, International Press,
2013, pp. 51–72, doi:10.4310/HHA.2013.v15.n1.a3.
short: P. Bendich, H. Edelsbrunner, D. Morozov, A. Patel, Homology, Homotopy and
Applications 15 (2013) 51–72.
date_created: 2018-12-11T11:59:58Z
date_published: 2013-05-01T00:00:00Z
date_updated: 2021-01-12T07:00:18Z
day: '01'
department:
- _id: HeEd
doi: 10.4310/HHA.2013.v15.n1.a3
external_id:
arxiv:
- '1102.3389'
intvolume: ' 15'
issue: '1'
language:
- iso: eng
main_file_link:
- open_access: '1'
url: https://arxiv.org/abs/1102.3389v1
month: '05'
oa: 1
oa_version: Preprint
page: 51 - 72
publication: Homology, Homotopy and Applications
publication_status: published
publisher: International Press
publist_id: '3930'
quality_controlled: '1'
scopus_import: 1
status: public
title: Homology and robustness of level and interlevel sets
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 15
year: '2013'
...
---
_id: '2863'
abstract:
- lang: eng
text: Neural populations encode information about their stimulus in a collective
fashion, by joint activity patterns of spiking and silence. A full account of
this mapping from stimulus to neural activity is given by the conditional probability
distribution over neural codewords given the sensory input. For large populations,
direct sampling of these distributions is impossible, and so we must rely on constructing
appropriate models. We show here that in a population of 100 retinal ganglion
cells in the salamander retina responding to temporal white-noise stimuli, dependencies
between cells play an important encoding role. We introduce the stimulus-dependent
maximum entropy (SDME) model—a minimal extension of the canonical linear-nonlinear
model of a single neuron, to a pairwise-coupled neural population. We find that
the SDME model gives a more accurate account of single cell responses and in particular
significantly outperforms uncoupled models in reproducing the distributions of
population codewords emitted in response to a stimulus. We show how the SDME model,
in conjunction with static maximum entropy models of population vocabulary, can
be used to estimate information-theoretic quantities like average surprise and
information transmission in a neural population.
article_number: e1002922
author:
- first_name: Einat
full_name: Granot Atedgi, Einat
last_name: Granot Atedgi
- first_name: Gasper
full_name: Tkacik, Gasper
id: 3D494DCA-F248-11E8-B48F-1D18A9856A87
last_name: Tkacik
orcid: 0000-0002-6699-1455
- first_name: Ronen
full_name: Segev, Ronen
last_name: Segev
- first_name: Elad
full_name: Schneidman, Elad
last_name: Schneidman
citation:
ama: Granot Atedgi E, Tkačik G, Segev R, Schneidman E. Stimulus-dependent maximum
entropy models of neural population codes. PLoS Computational Biology.
2013;9(3). doi:10.1371/journal.pcbi.1002922
apa: Granot Atedgi, E., Tkačik, G., Segev, R., & Schneidman, E. (2013). Stimulus-dependent
maximum entropy models of neural population codes. PLoS Computational Biology.
Public Library of Science. https://doi.org/10.1371/journal.pcbi.1002922
chicago: Granot Atedgi, Einat, Gašper Tkačik, Ronen Segev, and Elad Schneidman.
“Stimulus-Dependent Maximum Entropy Models of Neural Population Codes.” PLoS
Computational Biology. Public Library of Science, 2013. https://doi.org/10.1371/journal.pcbi.1002922.
ieee: E. Granot Atedgi, G. Tkačik, R. Segev, and E. Schneidman, “Stimulus-dependent
maximum entropy models of neural population codes,” PLoS Computational Biology,
vol. 9, no. 3. Public Library of Science, 2013.
ista: Granot Atedgi E, Tkačik G, Segev R, Schneidman E. 2013. Stimulus-dependent
maximum entropy models of neural population codes. PLoS Computational Biology.
9(3), e1002922.
mla: Granot Atedgi, Einat, et al. “Stimulus-Dependent Maximum Entropy Models of
Neural Population Codes.” PLoS Computational Biology, vol. 9, no. 3, e1002922,
Public Library of Science, 2013, doi:10.1371/journal.pcbi.1002922.
short: E. Granot Atedgi, G. Tkačik, R. Segev, E. Schneidman, PLoS Computational
Biology 9 (2013).
date_created: 2018-12-11T12:00:00Z
date_published: 2013-03-01T00:00:00Z
date_updated: 2021-01-12T07:00:20Z
day: '01'
ddc:
- '570'
department:
- _id: GaTk
doi: 10.1371/journal.pcbi.1002922
file:
- access_level: open_access
checksum: 5a30876c193209fa05b26db71845dd16
content_type: application/pdf
creator: system
date_created: 2018-12-12T10:14:45Z
date_updated: 2020-07-14T12:45:52Z
file_id: '5099'
file_name: IST-2013-120-v1+1_journal.pcbi.1002922.pdf
file_size: 1548120
relation: main_file
file_date_updated: 2020-07-14T12:45:52Z
has_accepted_license: '1'
intvolume: ' 9'
issue: '3'
language:
- iso: eng
month: '03'
oa: 1
oa_version: Published Version
publication: PLoS Computational Biology
publication_status: published
publisher: Public Library of Science
publist_id: '3926'
pubrep_id: '120'
quality_controlled: '1'
scopus_import: 1
status: public
title: Stimulus-dependent maximum entropy models of neural population codes
tmp:
image: /images/cc_by.png
legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
short: CC BY (4.0)
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 9
year: '2013'
...
---
_id: '2862'
abstract:
- lang: eng
text: Motile cilia perform crucial functions during embryonic development and throughout
adult life. Development of organs containing motile cilia involves regulation
of cilia formation (ciliogenesis) and formation of a luminal space (lumenogenesis)
in which cilia generate fluid flows. Control of ciliogenesis and lumenogenesis
is not yet fully understood, and it remains unclear whether these processes are
coupled. In the zebrafish embryo, lethal giant larvae 2 (lgl2) is expressed prominently
in ciliated organs. Lgl proteins are involved in establishing cell polarity and
have been implicated in vesicle trafficking. Here, we identified a role for Lgl2
in development of ciliated epithelia in Kupffer's vesicle, which directs left-right
asymmetry of the embryo; the otic vesicles, which give rise to the inner ear;
and the pronephric ducts of the kidney. Using Kupffer's vesicle as a model ciliated
organ, we found that depletion of Lgl2 disrupted lumen formation and reduced cilia
number and length. Immunofluorescence and time-lapse imaging of Kupffer's vesicle
morphogenesis in Lgl2-deficient embryos suggested cell adhesion defects and revealed
loss of the adherens junction component E-cadherin at lateral membranes. Genetic
interaction experiments indicate that Lgl2 interacts with Rab11a to regulate E-cadherin
and mediate lumen formation that is uncoupled from cilia formation. These results
uncover new roles and interactions for Lgl2 that are crucial for both lumenogenesis
and ciliogenesis and indicate that these processes are genetically separable in
zebrafish.
acknowledgement: Deposited in PMC for release after 12 months. We thank members of
the Amack lab for helpful discussions and Mahendra Sonawane for donating reagents.
author:
- first_name: Hwee
full_name: Tay, Hwee
last_name: Tay
- first_name: Sabrina
full_name: Schulze, Sabrina
last_name: Schulze
- first_name: Julien
full_name: Compagnon, Julien
id: 2E3E0988-F248-11E8-B48F-1D18A9856A87
last_name: Compagnon
- first_name: Fiona
full_name: Foley, Fiona
last_name: Foley
- first_name: Carl-Philipp J
full_name: Heisenberg, Carl-Philipp J
id: 39427864-F248-11E8-B48F-1D18A9856A87
last_name: Heisenberg
orcid: 0000-0002-0912-4566
- first_name: H Joseph
full_name: Yost, H Joseph
last_name: Yost
- first_name: Salim
full_name: Abdelilah Seyfried, Salim
last_name: Abdelilah Seyfried
- first_name: Jeffrey
full_name: Amack, Jeffrey
last_name: Amack
citation:
ama: Tay H, Schulze S, Compagnon J, et al. Lethal giant larvae 2 regulates development
of the ciliated organ Kupffer’s vesicle. Development. 2013;140(7):1550-1559.
doi:10.1242/dev.087130
apa: Tay, H., Schulze, S., Compagnon, J., Foley, F., Heisenberg, C.-P. J., Yost,
H. J., … Amack, J. (2013). Lethal giant larvae 2 regulates development of the
ciliated organ Kupffer’s vesicle. Development. Company of Biologists. https://doi.org/10.1242/dev.087130
chicago: Tay, Hwee, Sabrina Schulze, Julien Compagnon, Fiona Foley, Carl-Philipp
J Heisenberg, H Joseph Yost, Salim Abdelilah Seyfried, and Jeffrey Amack. “Lethal
Giant Larvae 2 Regulates Development of the Ciliated Organ Kupffer’s Vesicle.”
Development. Company of Biologists, 2013. https://doi.org/10.1242/dev.087130.
ieee: H. Tay et al., “Lethal giant larvae 2 regulates development of the
ciliated organ Kupffer’s vesicle,” Development, vol. 140, no. 7. Company
of Biologists, pp. 1550–1559, 2013.
ista: Tay H, Schulze S, Compagnon J, Foley F, Heisenberg C-PJ, Yost HJ, Abdelilah
Seyfried S, Amack J. 2013. Lethal giant larvae 2 regulates development of the
ciliated organ Kupffer’s vesicle. Development. 140(7), 1550–1559.
mla: Tay, Hwee, et al. “Lethal Giant Larvae 2 Regulates Development of the Ciliated
Organ Kupffer’s Vesicle.” Development, vol. 140, no. 7, Company of Biologists,
2013, pp. 1550–59, doi:10.1242/dev.087130.
short: H. Tay, S. Schulze, J. Compagnon, F. Foley, C.-P.J. Heisenberg, H.J. Yost,
S. Abdelilah Seyfried, J. Amack, Development 140 (2013) 1550–1559.
date_created: 2018-12-11T11:59:59Z
date_published: 2013-04-01T00:00:00Z
date_updated: 2021-01-12T07:00:20Z
day: '01'
department:
- _id: CaHe
doi: 10.1242/dev.087130
external_id:
pmid:
- '23482490'
intvolume: ' 140'
issue: '7'
language:
- iso: eng
main_file_link:
- open_access: '1'
url: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3596994/
month: '04'
oa: 1
oa_version: Submitted Version
page: 1550 - 1559
pmid: 1
publication: Development
publication_status: published
publisher: Company of Biologists
publist_id: '3927'
quality_controlled: '1'
scopus_import: 1
status: public
title: Lethal giant larvae 2 regulates development of the ciliated organ Kupffer’s
vesicle
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 140
year: '2013'
...
---
_id: '2861'
abstract:
- lang: eng
text: We consider a two-parameter family of piecewise linear maps in which the moduli
of the two slopes take different values. We provide numerical evidence of the
existence of some parameter regions in which the Lyapunov exponent and the topological
entropy remain constant. Analytical proof of this phenomenon is also given for
certain cases. Surprisingly however, the systems with that property are not conjugate
as we prove by using kneading theory.
article_number: '125101'
author:
- first_name: Vicente
full_name: Botella Soler, Vicente
id: 421234E8-F248-11E8-B48F-1D18A9856A87
last_name: Botella Soler
orcid: 0000-0002-8790-1914
- first_name: José
full_name: Oteo, José
last_name: Oteo
- first_name: Javier
full_name: Ros, Javier
last_name: Ros
- first_name: Paul
full_name: Glendinning, Paul
last_name: Glendinning
citation:
ama: 'Botella Soler V, Oteo J, Ros J, Glendinning P. Lyapunov exponent and topological
entropy plateaus in piecewise linear maps. Journal of Physics A: Mathematical
and Theoretical. 2013;46(12). doi:10.1088/1751-8113/46/12/125101'
apa: 'Botella Soler, V., Oteo, J., Ros, J., & Glendinning, P. (2013). Lyapunov
exponent and topological entropy plateaus in piecewise linear maps. Journal
of Physics A: Mathematical and Theoretical. IOP Publishing Ltd. https://doi.org/10.1088/1751-8113/46/12/125101'
chicago: 'Botella Soler, Vicente, José Oteo, Javier Ros, and Paul Glendinning. “Lyapunov
Exponent and Topological Entropy Plateaus in Piecewise Linear Maps.” Journal
of Physics A: Mathematical and Theoretical. IOP Publishing Ltd., 2013. https://doi.org/10.1088/1751-8113/46/12/125101.'
ieee: 'V. Botella Soler, J. Oteo, J. Ros, and P. Glendinning, “Lyapunov exponent
and topological entropy plateaus in piecewise linear maps,” Journal of Physics
A: Mathematical and Theoretical, vol. 46, no. 12. IOP Publishing Ltd., 2013.'
ista: 'Botella Soler V, Oteo J, Ros J, Glendinning P. 2013. Lyapunov exponent and
topological entropy plateaus in piecewise linear maps. Journal of Physics A: Mathematical
and Theoretical. 46(12), 125101.'
mla: 'Botella Soler, Vicente, et al. “Lyapunov Exponent and Topological Entropy
Plateaus in Piecewise Linear Maps.” Journal of Physics A: Mathematical and
Theoretical, vol. 46, no. 12, 125101, IOP Publishing Ltd., 2013, doi:10.1088/1751-8113/46/12/125101.'
short: 'V. Botella Soler, J. Oteo, J. Ros, P. Glendinning, Journal of Physics A:
Mathematical and Theoretical 46 (2013).'
date_created: 2018-12-11T11:59:59Z
date_published: 2013-03-29T00:00:00Z
date_updated: 2021-01-12T07:00:19Z
day: '29'
department:
- _id: GaTk
doi: 10.1088/1751-8113/46/12/125101
intvolume: ' 46'
issue: '12'
language:
- iso: eng
month: '03'
oa_version: None
publication: 'Journal of Physics A: Mathematical and Theoretical'
publication_status: published
publisher: IOP Publishing Ltd.
publist_id: '3928'
quality_controlled: '1'
scopus_import: 1
status: public
title: Lyapunov exponent and topological entropy plateaus in piecewise linear maps
type: journal_article
user_id: 3E5EF7F0-F248-11E8-B48F-1D18A9856A87
volume: 46
year: '2013'
...
---
_id: '2877'
abstract:
- lang: eng
text: 'Premise of the study: To reach favorable conditions for photosynthesis, seedlings
grow upward when deprived of light upon underground germination. To direct their
growth, they use their negative gravitropic capacity. Negative gravitropism is
under tight control of multiple hormones. • Methods: By counting the number of
standing plants in a population or by real time monitoring of the reorientation
of gravistimulated seedlings of Arabidopsis thaliana, we evaluated the negative
gravitropism of ethylene or brassinosteroid (BR) treated plants. Meta-analysis
of transcriptomic data on AUX / IAA genes was gathered, and subsequent mutant
analysis was performed. • Key results: Ethylene and BR have opposite effects in
regulating shoot gravitropism. Lack of BR enhances gravitropic reorientation in
2-d-old seedlings, whereas ethylene does not. Lack of ethylene signaling results
in enhanced BR sensitivity. Ethylene and BRs regulate overlapping sets of AUX
/ IAA genes. BRs regulate a wider range of auxin signaling components than ethylene.
• Conclusions: Upward growth in seedlings depends strongly on the internal hormonal
balance. Endogenous ethylene stimulates, whereas BRs reduce negative gravitropism
in a manner that depends on the function of different, yet overlapping sets of
auxin signaling components.'
author:
- first_name: Filip
full_name: Vandenbussche, Filip
last_name: Vandenbussche
- first_name: Pieter
full_name: Callebert, Pieter
last_name: Callebert
- first_name: Petra
full_name: Žádníková, Petra
last_name: Žádníková
- first_name: Eva
full_name: Eva Benková
id: 38F4F166-F248-11E8-B48F-1D18A9856A87
last_name: Benková
orcid: 0000-0002-8510-9739
- first_name: Dominique
full_name: Van Der Straeten, Dominique
last_name: Van Der Straeten
citation:
ama: Vandenbussche F, Callebert P, Žádníková P, Benková E, Van Der Straeten D. Brassinosteroid
control of shoot gravitropism interacts with ethylene and depends on auxin signaling
components. American Journal of Botany. 2013;100(1):215-225. doi:10.3732/ajb.1200264
apa: Vandenbussche, F., Callebert, P., Žádníková, P., Benková, E., & Van Der
Straeten, D. (2013). Brassinosteroid control of shoot gravitropism interacts with
ethylene and depends on auxin signaling components. American Journal of Botany.
Botanical Society of America. https://doi.org/10.3732/ajb.1200264
chicago: Vandenbussche, Filip, Pieter Callebert, Petra Žádníková, Eva Benková, and
Dominique Van Der Straeten. “Brassinosteroid Control of Shoot Gravitropism Interacts
with Ethylene and Depends on Auxin Signaling Components.” American Journal
of Botany. Botanical Society of America, 2013. https://doi.org/10.3732/ajb.1200264.
ieee: F. Vandenbussche, P. Callebert, P. Žádníková, E. Benková, and D. Van Der Straeten,
“Brassinosteroid control of shoot gravitropism interacts with ethylene and depends
on auxin signaling components,” American Journal of Botany, vol. 100, no.
1. Botanical Society of America, pp. 215–225, 2013.
ista: Vandenbussche F, Callebert P, Žádníková P, Benková E, Van Der Straeten D.
2013. Brassinosteroid control of shoot gravitropism interacts with ethylene and
depends on auxin signaling components. American Journal of Botany. 100(1), 215–225.
mla: Vandenbussche, Filip, et al. “Brassinosteroid Control of Shoot Gravitropism
Interacts with Ethylene and Depends on Auxin Signaling Components.” American
Journal of Botany, vol. 100, no. 1, Botanical Society of America, 2013, pp.
215–25, doi:10.3732/ajb.1200264.
short: F. Vandenbussche, P. Callebert, P. Žádníková, E. Benková, D. Van Der Straeten,
American Journal of Botany 100 (2013) 215–225.
date_created: 2018-12-11T12:00:06Z
date_published: 2013-01-01T00:00:00Z
date_updated: 2021-01-12T07:00:25Z
day: '01'
doi: 10.3732/ajb.1200264
extern: 1
intvolume: ' 100'
issue: '1'
month: '01'
page: 215 - 225
publication: American Journal of Botany
publication_status: published
publisher: Botanical Society of America
publist_id: '3883'
quality_controlled: 0
status: public
title: Brassinosteroid control of shoot gravitropism interacts with ethylene and depends
on auxin signaling components
type: journal_article
volume: 100
year: '2013'
...
---
_id: '2883'
abstract:
- lang: eng
text: Plant architecture is influenced by the polar, cell-to-cell transport of auxin
that is primarily provided and regulated by plasma membrane efflux catalysts of
the PIN-FORMED and B family of ABC transporter (ABCB) classes. The latter were
shown to require the functionality of the FK506 binding protein42 TWISTED DWARF1
(TWD1), although underlying mechanisms are unclear. By genetic manipulation of
TWD1 expression, we show here that TWD1 affects shootward root auxin reflux and,
thus, downstream developmental traits, such as epidermal twisting and gravitropism
of the root. Using immunological assays, we demonstrate a predominant lateral,
mainly outward-facing, plasma membrane location for TWD1 in the root epidermis
characterized by the lateral marker ABC transporter G36/PLEIOTROPIC DRUG-RESISTANCE8/PENETRATION3.
At these epidermal plasma membrane domains, TWD1 colocalizes with nonpolar ABCB1.
In planta bioluminescence resonance energy transfer analysis was used to verify
specific ABC transporter B1 (ABCB1)-TWD1 interaction. Our data support a model
in which TWD1 promotes lateral ABCB-mediated auxin efflux via protein-protein
interaction at the plasma membrane, minimizing reflux from the root apoplast into
the cytoplasm.
acknowledgement: We would thank Vincent Vincenzetti and Laurence Charrier for excellent
technical assistance, A. von Arnim for the donation of BRET vectors, E. Spalding
for TWD1-CFP, TWD1-CFP/29-1-GFP/ER-YFP, and ABCB4-GFP lines, M. Palmgren for discussion
and support, and E. Martinoia for TT12 cDNA, support, and mentorship. Imaging data
were partially collected at the Center for Advanced Bioimaging, University of Copenhagen,
Denmark. This work was supported by grants from the Novartis Foundation (to M.G.),
from the Danish Research School for Biotechnology (to M.G. and A.S.), from the Forschungskredit
of the University of Zurich (to A.B.), from the Pool de Recherche of the University
of Fribourg (to M.G.), and from the Swiss National Funds (to M.G.). M.G. dedicates
this work to his father, who passed away during the resubmission process.
author:
- first_name: Bangjun
full_name: Wang, Bangjun
last_name: Wang
- first_name: Aurélien
full_name: Bailly, Aurélien
last_name: Bailly
- first_name: Marta
full_name: Zwiewk, Marta
last_name: Zwiewk
- first_name: Sina
full_name: Henrichs, Sina
last_name: Henrichs
- first_name: Elisa
full_name: Azzarello, Elisa
last_name: Azzarello
- first_name: Stefano
full_name: Mancuso, Stefano
last_name: Mancuso
- first_name: Masayoshi
full_name: Maeshima, Masayoshi
last_name: Maeshima
- first_name: Jirí
full_name: Friml, Jirí
id: 4159519E-F248-11E8-B48F-1D18A9856A87
last_name: Friml
orcid: 0000-0002-8302-7596
- first_name: Alexander
full_name: Schulz, Alexander
last_name: Schulz
- first_name: Markus
full_name: Geisler, Markus
last_name: Geisler
citation:
ama: Wang B, Bailly A, Zwiewk M, et al. Arabidopsis TWISTED DWARF1 functionally
interacts with auxin exporter ABCB1 on the root plasma membrane. Plant Cell.
2013;25(1):202-214. doi:10.1105/tpc.112.105999
apa: Wang, B., Bailly, A., Zwiewk, M., Henrichs, S., Azzarello, E., Mancuso, S.,
… Geisler, M. (2013). Arabidopsis TWISTED DWARF1 functionally interacts with auxin
exporter ABCB1 on the root plasma membrane. Plant Cell. American Society
of Plant Biologists. https://doi.org/10.1105/tpc.112.105999
chicago: Wang, Bangjun, Aurélien Bailly, Marta Zwiewk, Sina Henrichs, Elisa Azzarello,
Stefano Mancuso, Masayoshi Maeshima, Jiří Friml, Alexander Schulz, and Markus
Geisler. “Arabidopsis TWISTED DWARF1 Functionally Interacts with Auxin Exporter
ABCB1 on the Root Plasma Membrane.” Plant Cell. American Society of Plant
Biologists, 2013. https://doi.org/10.1105/tpc.112.105999.
ieee: B. Wang et al., “Arabidopsis TWISTED DWARF1 functionally interacts
with auxin exporter ABCB1 on the root plasma membrane,” Plant Cell, vol.
25, no. 1. American Society of Plant Biologists, pp. 202–214, 2013.
ista: Wang B, Bailly A, Zwiewk M, Henrichs S, Azzarello E, Mancuso S, Maeshima M,
Friml J, Schulz A, Geisler M. 2013. Arabidopsis TWISTED DWARF1 functionally interacts
with auxin exporter ABCB1 on the root plasma membrane. Plant Cell. 25(1), 202–214.
mla: Wang, Bangjun, et al. “Arabidopsis TWISTED DWARF1 Functionally Interacts with
Auxin Exporter ABCB1 on the Root Plasma Membrane.” Plant Cell, vol. 25,
no. 1, American Society of Plant Biologists, 2013, pp. 202–14, doi:10.1105/tpc.112.105999.
short: B. Wang, A. Bailly, M. Zwiewk, S. Henrichs, E. Azzarello, S. Mancuso, M.
Maeshima, J. Friml, A. Schulz, M. Geisler, Plant Cell 25 (2013) 202–214.
date_created: 2018-12-11T12:00:08Z
date_published: 2013-01-01T00:00:00Z
date_updated: 2021-01-12T07:00:28Z
day: '01'
department:
- _id: JiFr
doi: 10.1105/tpc.112.105999
external_id:
pmid:
- '23321285'
intvolume: ' 25'
issue: '1'
language:
- iso: eng
main_file_link:
- open_access: '1'
url: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3584535/
month: '01'
oa: 1
oa_version: Submitted Version
page: 202 - 214
pmid: 1
publication: Plant Cell
publication_status: published
publisher: American Society of Plant Biologists
publist_id: '3878'
quality_controlled: '1'
scopus_import: 1
status: public
title: Arabidopsis TWISTED DWARF1 functionally interacts with auxin exporter ABCB1
on the root plasma membrane
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 25
year: '2013'
...
---
_id: '2880'
abstract:
- lang: eng
text: Lateral root (LR) formation is initiated when pericycle cells accumulate auxin,
thereby acquiring founder cell (FC) status and triggering asymmetric cell divisions,
giving rise to a new primordium. How this auxin maximum in pericycle cells builds
up and remains focused is not understood. We report that the endodermis plays
an active role in the regulation of auxin accumulation and is instructive for
FCs to progress during the LR initiation (LRI) phase. We describe the functional
importance of a PIN3 (PIN-formed) auxin efflux carrier-dependent hormone reflux
pathway between overlaying endodermal and pericycle FCs. Disrupting this reflux
pathway causes dramatic defects in the progress of FCs towards the next initiation
phase. Our data identify an unexpected regulatory function for the endodermis
in LRI as part of the fine-tuning mechanism that appears to act as a check point
in LR organogenesis after FCs are specified.
author:
- first_name: Peter
full_name: Marhavy, Peter
id: 3F45B078-F248-11E8-B48F-1D18A9856A87
last_name: Marhavy
orcid: 0000-0001-5227-5741
- first_name: Marleen
full_name: Vanstraelen, Marleen
last_name: Vanstraelen
- first_name: Bert
full_name: De Rybel, Bert
last_name: De Rybel
- first_name: Ding
full_name: Zhaojun, Ding
last_name: Zhaojun
- first_name: Malcolm
full_name: Bennett, Malcolm
last_name: Bennett
- first_name: Tom
full_name: Beeckman, Tom
last_name: Beeckman
- first_name: Eva
full_name: Benková, Eva
id: 38F4F166-F248-11E8-B48F-1D18A9856A87
last_name: Benková
orcid: 0000-0002-8510-9739
citation:
ama: Marhavý P, Vanstraelen M, De Rybel B, et al. Auxin reflux between the endodermis
and pericycle promotes lateral root initiation. EMBO Journal. 2013;32(1):149-158.
doi:10.1038/emboj.2012.303
apa: Marhavý, P., Vanstraelen, M., De Rybel, B., Zhaojun, D., Bennett, M., Beeckman,
T., & Benková, E. (2013). Auxin reflux between the endodermis and pericycle
promotes lateral root initiation. EMBO Journal. Wiley-Blackwell. https://doi.org/10.1038/emboj.2012.303
chicago: Marhavý, Peter, Marleen Vanstraelen, Bert De Rybel, Ding Zhaojun, Malcolm
Bennett, Tom Beeckman, and Eva Benková. “Auxin Reflux between the Endodermis and
Pericycle Promotes Lateral Root Initiation.” EMBO Journal. Wiley-Blackwell,
2013. https://doi.org/10.1038/emboj.2012.303.
ieee: P. Marhavý et al., “Auxin reflux between the endodermis and pericycle
promotes lateral root initiation,” EMBO Journal, vol. 32, no. 1. Wiley-Blackwell,
pp. 149–158, 2013.
ista: Marhavý P, Vanstraelen M, De Rybel B, Zhaojun D, Bennett M, Beeckman T, Benková
E. 2013. Auxin reflux between the endodermis and pericycle promotes lateral root
initiation. EMBO Journal. 32(1), 149–158.
mla: Marhavý, Peter, et al. “Auxin Reflux between the Endodermis and Pericycle Promotes
Lateral Root Initiation.” EMBO Journal, vol. 32, no. 1, Wiley-Blackwell,
2013, pp. 149–58, doi:10.1038/emboj.2012.303.
short: P. Marhavý, M. Vanstraelen, B. De Rybel, D. Zhaojun, M. Bennett, T. Beeckman,
E. Benková, EMBO Journal 32 (2013) 149–158.
date_created: 2018-12-11T12:00:07Z
date_published: 2013-01-09T00:00:00Z
date_updated: 2021-01-12T07:00:27Z
day: '09'
department:
- _id: EvBe
doi: 10.1038/emboj.2012.303
ec_funded: 1
external_id:
pmid:
- '23178590'
intvolume: ' 32'
issue: '1'
language:
- iso: eng
main_file_link:
- open_access: '1'
url: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3545298/
month: '01'
oa: 1
oa_version: Submitted Version
page: 149 - 158
pmid: 1
project:
- _id: 253FCA6A-B435-11E9-9278-68D0E5697425
call_identifier: FP7
grant_number: '207362'
name: Hormonal cross-talk in plant organogenesis
publication: EMBO Journal
publication_status: published
publisher: Wiley-Blackwell
publist_id: '3882'
quality_controlled: '1'
scopus_import: 1
status: public
title: Auxin reflux between the endodermis and pericycle promotes lateral root initiation
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 32
year: '2013'
...
---
_id: '2882'
abstract:
- lang: eng
text: Gravitropic bending of plant organs is mediated by an asymmetric signaling
of the plant hormone auxin between the upper and lower side of the respective
organ. Here, we show that also another plant hormone, gibberellic acid (GA), shows
asymmetric action during gravitropic responses. Immunodetection using an antibody
against GA and monitoring GA signaling output by downstream degradation of DELLA
proteins revealed an asymmetric GA distribution and response with the maximum
at the lower side of gravistimulated roots. Genetic or pharmacological manipulation
of GA levels or response affects gravity-mediated auxin redistribution and root
bending response. The higher GA levels at the lower side of the root correlate
with increased amounts of PIN-FORMED2 (PIN2) auxin transporter at the plasma membrane.
The observed increase in PIN2 stability is caused by a specific GA effect on trafficking
of PIN proteins to lytic vacuoles that presumably occurs downstream of brefeldin
A-sensitive endosomes. Our results suggest that asymmetric auxin distribution
instructive for gravity-induced differential growth is consolidated by the asymmetric
action of GA that stabilizes the PIN-dependent auxin stream along the lower side
of gravistimulated roots.
author:
- first_name: Christian
full_name: Löfke, Christian
last_name: Löfke
- first_name: Marta
full_name: Zwiewka, Marta
last_name: Zwiewka
- first_name: Ingo
full_name: Heilmann, Ingo
last_name: Heilmann
- first_name: Marc
full_name: Van Montagu, Marc
last_name: Van Montagu
- first_name: Thomas
full_name: Teichmann, Thomas
last_name: Teichmann
- first_name: Jirí
full_name: Friml, Jirí
id: 4159519E-F248-11E8-B48F-1D18A9856A87
last_name: Friml
orcid: 0000-0002-8302-7596
citation:
ama: Löfke C, Zwiewka M, Heilmann I, Van Montagu M, Teichmann T, Friml J. Asymmetric
gibberellin signaling regulates vacuolar trafficking of PIN auxin transporters
during root gravitropism. PNAS. 2013;110(9):3627-3632. doi:10.1073/pnas.1300107110
apa: Löfke, C., Zwiewka, M., Heilmann, I., Van Montagu, M., Teichmann, T., &
Friml, J. (2013). Asymmetric gibberellin signaling regulates vacuolar trafficking
of PIN auxin transporters during root gravitropism. PNAS. National Academy
of Sciences. https://doi.org/10.1073/pnas.1300107110
chicago: Löfke, Christian, Marta Zwiewka, Ingo Heilmann, Marc Van Montagu, Thomas
Teichmann, and Jiří Friml. “Asymmetric Gibberellin Signaling Regulates Vacuolar
Trafficking of PIN Auxin Transporters during Root Gravitropism.” PNAS.
National Academy of Sciences, 2013. https://doi.org/10.1073/pnas.1300107110.
ieee: C. Löfke, M. Zwiewka, I. Heilmann, M. Van Montagu, T. Teichmann, and J. Friml,
“Asymmetric gibberellin signaling regulates vacuolar trafficking of PIN auxin
transporters during root gravitropism,” PNAS, vol. 110, no. 9. National
Academy of Sciences, pp. 3627–3632, 2013.
ista: Löfke C, Zwiewka M, Heilmann I, Van Montagu M, Teichmann T, Friml J. 2013.
Asymmetric gibberellin signaling regulates vacuolar trafficking of PIN auxin transporters
during root gravitropism. PNAS. 110(9), 3627–3632.
mla: Löfke, Christian, et al. “Asymmetric Gibberellin Signaling Regulates Vacuolar
Trafficking of PIN Auxin Transporters during Root Gravitropism.” PNAS,
vol. 110, no. 9, National Academy of Sciences, 2013, pp. 3627–32, doi:10.1073/pnas.1300107110.
short: C. Löfke, M. Zwiewka, I. Heilmann, M. Van Montagu, T. Teichmann, J. Friml,
PNAS 110 (2013) 3627–3632.
date_created: 2018-12-11T12:00:07Z
date_published: 2013-02-26T00:00:00Z
date_updated: 2021-01-12T07:00:27Z
day: '26'
department:
- _id: JiFr
doi: 10.1073/pnas.1300107110
external_id:
pmid:
- '23391733'
intvolume: ' 110'
issue: '9'
language:
- iso: eng
main_file_link:
- open_access: '1'
url: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3587205/
month: '02'
oa: 1
oa_version: Submitted Version
page: 3627 - 3632
pmid: 1
publication: PNAS
publication_status: published
publisher: National Academy of Sciences
publist_id: '3879'
quality_controlled: '1'
scopus_import: 1
status: public
title: Asymmetric gibberellin signaling regulates vacuolar trafficking of PIN auxin
transporters during root gravitropism
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 110
year: '2013'
...
---
_id: '2885'
abstract:
- lang: eng
text: 'This volume contains the post-proceedings of the 8th Doctoral Workshop on
Mathematical and Engineering Methods in Computer Science, MEMICS 2012, held in
Znojmo, Czech Republic, in October, 2012. The 13 thoroughly revised papers were
carefully selected out of 31 submissions and are presented together with 6 invited
papers. The topics covered by the papers include: computer-aided analysis and
verification, applications of game theory in computer science, networks and security,
modern trends of graph theory in computer science, electronic systems design and
testing, and quantum information processing.'
acknowledgement: Red Hat Czech Republic, Y Soft
alternative_title:
- LNCS
citation:
ama: Kucera A, Henzinger TA, Nesetril J, Vojnar T, Antos D, eds. Mathematical
and Engineering Methods in Computer Science. Vol 7721. Springer; 2013:1-228.
doi:10.1007/978-3-642-36046-6
apa: 'Kucera, A., Henzinger, T. A., Nesetril, J., Vojnar, T., & Antos, D. (Eds.).
(2013). Mathematical and Engineering Methods in Computer Science (Vol.
7721, pp. 1–228). Presented at the MEMICS: Mathematical and Engineering methods
in computer science, Znojmo, Czech Republic: Springer. https://doi.org/10.1007/978-3-642-36046-6'
chicago: Kucera, Antonin, Thomas A Henzinger, Jaroslav Nesetril, Tomas Vojnar, and
David Antos, eds. Mathematical and Engineering Methods in Computer Science.
Vol. 7721. Lecture Notes in Computer Science. Springer, 2013. https://doi.org/10.1007/978-3-642-36046-6.
ieee: A. Kucera, T. A. Henzinger, J. Nesetril, T. Vojnar, and D. Antos, Eds., Mathematical
and Engineering Methods in Computer Science, vol. 7721. Springer, 2013, pp.
1–228.
ista: Kucera A, Henzinger TA, Nesetril J, Vojnar T, Antos D eds. 2013. Mathematical
and Engineering Methods in Computer Science, Springer,p.
mla: Kucera, Antonin, et al., editors. Mathematical and Engineering Methods in
Computer Science. Vol. 7721, Springer, 2013, pp. 1–228, doi:10.1007/978-3-642-36046-6.
short: A. Kucera, T.A. Henzinger, J. Nesetril, T. Vojnar, D. Antos, eds., Mathematical
and Engineering Methods in Computer Science, Springer, 2013.
conference:
end_date: 2012-10-28
location: Znojmo, Czech Republic
name: 'MEMICS: Mathematical and Engineering methods in computer science'
start_date: 2012-10-25
date_created: 2018-12-11T12:00:08Z
date_published: 2013-01-09T00:00:00Z
date_updated: 2019-08-02T12:37:55Z
day: '09'
department:
- _id: ToHe
doi: 10.1007/978-3-642-36046-6
editor:
- first_name: Antonin
full_name: Kucera, Antonin
last_name: Kucera
- first_name: Thomas A
full_name: Henzinger, Thomas A
id: 40876CD8-F248-11E8-B48F-1D18A9856A87
last_name: Henzinger
orcid: 0000−0002−2985−7724
- first_name: Jaroslav
full_name: Nesetril, Jaroslav
last_name: Nesetril
- first_name: Tomas
full_name: Vojnar, Tomas
last_name: Vojnar
- first_name: David
full_name: Antos, David
last_name: Antos
intvolume: ' 7721'
language:
- iso: eng
month: '01'
oa_version: None
page: 1 - 228
publication_status: published
publisher: Springer
publist_id: '3874'
quality_controlled: '1'
series_title: Lecture Notes in Computer Science
status: public
title: Mathematical and Engineering Methods in Computer Science
type: conference_editor
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 7721
year: '2013'
...
---
_id: '2881'
abstract:
- lang: eng
text: The puzzle piece-shaped Arabidopsis leaf pavement cells (PCs) with interdigitated
lobes and indents is a good model system to investigate the mechanisms that coordinate
cell polarity and shape formation within a tissue. Auxin has been shown to coordinate
the interdigitation by activating ROP GTPase-dependent signaling pathways. To
identify additional components or mechanisms, we screened for mutants with abnormal
PC morphogenesis and found that cytokinin signaling regulates the PC interdigitation
pattern. Reduction in cytokinin accumulation and defects in cytokinin signaling
(such as in ARR7-over-expressing lines, the ahk3cre1 cytokinin receptor mutant,
and the ahp12345 cytokinin signaling mutant) enhanced PC interdigitation, whereas
over-production of cytokinin and over-activation of cytokinin signaling in an
ARR20 over-expression line delayed or abolished PC interdigitation throughout
the cotyledon. Genetic and biochemical analyses suggest that cytokinin signaling
acts upstream of ROPs to suppress the formation of interdigitated pattern. Our
results provide novel mechanistic understanding of the pathways controlling PC
shape and uncover a new role for cytokinin signaling in cell morphogenesis.
acknowledgement: is work was supported by grants from the US National Institute of
General Medical Sciences (GM081451 and GM081451-03S2) to ZY. We thank National Science
Foundation grant (IOS-1147250) to GVR and MX. HL and DL were partially supported
by the Chinese Scholarship Council.
author:
- first_name: Hongjiang
full_name: Hongjiang Li
id: 33CA54A6-F248-11E8-B48F-1D18A9856A87
last_name: Li
orcid: 0000-0001-5039-9660
- first_name: Tongda
full_name: Xu, Tongda
last_name: Xu
- first_name: Deshu
full_name: Lin, Deshu
last_name: Lin
- first_name: Mingzhang
full_name: Wen, Mingzhang
last_name: Wen
- first_name: Mingtang
full_name: Xie, Mingtang
last_name: Xie
- first_name: Jérôme
full_name: Duclercq, Jérôme
last_name: Duclercq
- first_name: Agnieszka
full_name: Bielach, Agnieszka
last_name: Bielach
- first_name: Jungmook
full_name: Kim, Jungmook
last_name: Kim
- first_name: G Venugopala
full_name: Reddy, G Venugopala
last_name: Reddy
- first_name: Jianru
full_name: Zuo, Jianru
last_name: Zuo
- first_name: Eva
full_name: Eva Benková
id: 38F4F166-F248-11E8-B48F-1D18A9856A87
last_name: Benková
orcid: 0000-0002-8510-9739
- first_name: Jirí
full_name: Jirí Friml
id: 4159519E-F248-11E8-B48F-1D18A9856A87
last_name: Friml
orcid: 0000-0002-8302-7596
- first_name: Hongwei
full_name: Guo, Hongwei
last_name: Guo
- first_name: Zhenbiao
full_name: Yang, Zhenbiao
last_name: Yang
citation:
ama: Li H, Xu T, Lin D, et al. Cytokinin signaling regulates pavement cell morphogenesis
in Arabidopsis. Cell Research. 2013;23(2):290-299. doi:10.1038/cr.2012.146
apa: Li, H., Xu, T., Lin, D., Wen, M., Xie, M., Duclercq, J., … Yang, Z. (2013).
Cytokinin signaling regulates pavement cell morphogenesis in Arabidopsis. Cell
Research. Nature Publishing Group. https://doi.org/10.1038/cr.2012.146
chicago: Li, Hongjiang, Tongda Xu, Deshu Lin, Mingzhang Wen, Mingtang Xie, Jérôme
Duclercq, Agnieszka Bielach, et al. “Cytokinin Signaling Regulates Pavement Cell
Morphogenesis in Arabidopsis.” Cell Research. Nature Publishing Group,
2013. https://doi.org/10.1038/cr.2012.146.
ieee: H. Li et al., “Cytokinin signaling regulates pavement cell morphogenesis
in Arabidopsis,” Cell Research, vol. 23, no. 2. Nature Publishing Group,
pp. 290–299, 2013.
ista: Li H, Xu T, Lin D, Wen M, Xie M, Duclercq J, Bielach A, Kim J, Reddy GV, Zuo
J, Benková E, Friml J, Guo H, Yang Z. 2013. Cytokinin signaling regulates pavement
cell morphogenesis in Arabidopsis. Cell Research. 23(2), 290–299.
mla: Li, Hongjiang, et al. “Cytokinin Signaling Regulates Pavement Cell Morphogenesis
in Arabidopsis.” Cell Research, vol. 23, no. 2, Nature Publishing Group,
2013, pp. 290–99, doi:10.1038/cr.2012.146.
short: H. Li, T. Xu, D. Lin, M. Wen, M. Xie, J. Duclercq, A. Bielach, J. Kim, G.V.
Reddy, J. Zuo, E. Benková, J. Friml, H. Guo, Z. Yang, Cell Research 23 (2013)
290–299.
date_created: 2018-12-11T12:00:07Z
date_published: 2013-02-01T00:00:00Z
date_updated: 2021-01-12T07:00:27Z
day: '01'
doi: 10.1038/cr.2012.146
extern: 1
intvolume: ' 23'
issue: '2'
main_file_link:
- open_access: '1'
url: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3567823/
month: '02'
oa: 1
page: 290 - 299
publication: Cell Research
publication_status: published
publisher: Nature Publishing Group
publist_id: '3881'
quality_controlled: 0
status: public
title: Cytokinin signaling regulates pavement cell morphogenesis in Arabidopsis
type: journal_article
volume: 23
year: '2013'
...
---
_id: '2884'
author:
- first_name: Jean-Léon
full_name: Maître, Jean-Léon
id: 48F1E0D8-F248-11E8-B48F-1D18A9856A87
last_name: Maître
orcid: 0000-0002-3688-1474
- first_name: Hélène
full_name: Berthoumieux, Hélène
last_name: Berthoumieux
- first_name: Gabriel
full_name: Krens, Gabriel
id: 2B819732-F248-11E8-B48F-1D18A9856A87
last_name: Krens
orcid: 0000-0003-4761-5996
- first_name: Guillaume
full_name: Salbreux, Guillaume
last_name: Salbreux
- first_name: Frank
full_name: Julicher, Frank
last_name: Julicher
- first_name: Ewa
full_name: Paluch, Ewa
last_name: Paluch
- first_name: Carl-Philipp J
full_name: Heisenberg, Carl-Philipp J
id: 39427864-F248-11E8-B48F-1D18A9856A87
last_name: Heisenberg
orcid: 0000-0002-0912-4566
citation:
ama: Maître J-L, Berthoumieux H, Krens G, et al. Cell adhesion mechanics of zebrafish
gastrulation. Medecine Sciences. 2013;29(2):147-150. doi:10.1051/medsci/2013292011
apa: Maître, J.-L., Berthoumieux, H., Krens, G., Salbreux, G., Julicher, F., Paluch,
E., & Heisenberg, C.-P. J. (2013). Cell adhesion mechanics of zebrafish gastrulation.
Medecine Sciences. Éditions Médicales et Scientifiques. https://doi.org/10.1051/medsci/2013292011
chicago: Maître, Jean-Léon, Hélène Berthoumieux, Gabriel Krens, Guillaume Salbreux,
Frank Julicher, Ewa Paluch, and Carl-Philipp J Heisenberg. “Cell Adhesion Mechanics
of Zebrafish Gastrulation.” Medecine Sciences. Éditions Médicales et Scientifiques,
2013. https://doi.org/10.1051/medsci/2013292011.
ieee: J.-L. Maître et al., “Cell adhesion mechanics of zebrafish gastrulation,”
Medecine Sciences, vol. 29, no. 2. Éditions Médicales et Scientifiques,
pp. 147–150, 2013.
ista: Maître J-L, Berthoumieux H, Krens G, Salbreux G, Julicher F, Paluch E, Heisenberg
C-PJ. 2013. Cell adhesion mechanics of zebrafish gastrulation. Medecine Sciences.
29(2), 147–150.
mla: Maître, Jean-Léon, et al. “Cell Adhesion Mechanics of Zebrafish Gastrulation.”
Medecine Sciences, vol. 29, no. 2, Éditions Médicales et Scientifiques,
2013, pp. 147–50, doi:10.1051/medsci/2013292011.
short: J.-L. Maître, H. Berthoumieux, G. Krens, G. Salbreux, F. Julicher, E. Paluch,
C.-P.J. Heisenberg, Medecine Sciences 29 (2013) 147–150.
date_created: 2018-12-11T12:00:08Z
date_published: 2013-02-01T00:00:00Z
date_updated: 2021-01-12T07:00:28Z
day: '01'
department:
- _id: CaHe
doi: 10.1051/medsci/2013292011
intvolume: ' 29'
issue: '2'
language:
- iso: eng
month: '02'
oa_version: None
page: 147 - 150
project:
- _id: 252064B8-B435-11E9-9278-68D0E5697425
grant_number: HE_3231/6-1
name: Analysis of the Formation and Function of Different Cell Protusion Types During
Cell Migration in Vivo
- _id: 2527D5CC-B435-11E9-9278-68D0E5697425
call_identifier: FWF
grant_number: I 812-B12
name: Cell Cortex and Germ Layer Formation in Zebrafish Gastrulation
publication: Medecine Sciences
publication_status: published
publisher: Éditions Médicales et Scientifiques
publist_id: '3877'
quality_controlled: '1'
scopus_import: 1
status: public
title: Cell adhesion mechanics of zebrafish gastrulation
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 29
year: '2013'
...
---
_id: '2886'
abstract:
- lang: eng
text: We focus on the realizability problem of Message Sequence Graphs (MSG), i.e.
the problem whether a given MSG specification is correctly distributable among
parallel components communicating via messages. This fundamental problem of MSG
is known to be undecidable. We introduce a well motivated restricted class of
MSG, so called controllable-choice MSG, and show that all its models are realizable
and moreover it is decidable whether a given MSG model is a member of this class.
In more detail, this class of MSG specifications admits a deadlock-free realization
by overloading existing messages with additional bounded control data. We also
show that the presented class is the largest known subclass of MSG that allows
for deadlock-free realization.
alternative_title:
- LNCS
author:
- first_name: Martin
full_name: Chmelik, Martin
id: 3624234E-F248-11E8-B48F-1D18A9856A87
last_name: Chmelik
- first_name: Vojtěch
full_name: Řehák, Vojtěch
last_name: Řehák
citation:
ama: Chmelik M, Řehák V. Controllable-choice message sequence graphs. 2013;7721:118-130.
doi:10.1007/978-3-642-36046-6_12
apa: 'Chmelik, M., & Řehák, V. (2013). Controllable-choice message sequence
graphs. Presented at the MEMICS: Mathematical and Engineering Methods in Computer
Science, Znojmo, Czech Republic: Springer. https://doi.org/10.1007/978-3-642-36046-6_12'
chicago: Chmelik, Martin, and Vojtěch Řehák. “Controllable-Choice Message Sequence
Graphs.” Lecture Notes in Computer Science. Springer, 2013. https://doi.org/10.1007/978-3-642-36046-6_12.
ieee: M. Chmelik and V. Řehák, “Controllable-choice message sequence graphs,” vol.
7721. Springer, pp. 118–130, 2013.
ista: Chmelik M, Řehák V. 2013. Controllable-choice message sequence graphs. 7721,
118–130.
mla: Chmelik, Martin, and Vojtěch Řehák. Controllable-Choice Message Sequence
Graphs. Vol. 7721, Springer, 2013, pp. 118–30, doi:10.1007/978-3-642-36046-6_12.
short: M. Chmelik, V. Řehák, 7721 (2013) 118–130.
conference:
end_date: 2012-10-28
location: Znojmo, Czech Republic
name: 'MEMICS: Mathematical and Engineering Methods in Computer Science'
start_date: 2012-10-25
date_created: 2018-12-11T12:00:09Z
date_published: 2013-01-09T00:00:00Z
date_updated: 2020-08-11T10:09:52Z
day: '09'
department:
- _id: KrCh
doi: 10.1007/978-3-642-36046-6_12
ec_funded: 1
intvolume: ' 7721'
language:
- iso: eng
main_file_link:
- open_access: '1'
url: http://arxiv.org/abs/1209.4499
month: '01'
oa: 1
oa_version: Submitted Version
page: 118 - 130
project:
- _id: 2584A770-B435-11E9-9278-68D0E5697425
call_identifier: FWF
grant_number: P 23499-N23
name: Modern Graph Algorithmic Techniques in Formal Verification
- _id: 25863FF4-B435-11E9-9278-68D0E5697425
call_identifier: FWF
grant_number: S11407
name: Game Theory
- _id: 2581B60A-B435-11E9-9278-68D0E5697425
call_identifier: FP7
grant_number: '279307'
name: 'Quantitative Graph Games: Theory and Applications'
- _id: 2587B514-B435-11E9-9278-68D0E5697425
name: Microsoft Research Faculty Fellowship
publication_status: published
publisher: Springer
publist_id: '3873'
quality_controlled: '1'
scopus_import: 1
series_title: Lecture Notes in Computer Science
status: public
title: Controllable-choice message sequence graphs
type: conference
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 7721
year: '2013'
...
---
_id: '2887'
abstract:
- lang: eng
text: 'Root system growth and development is highly plastic and is influenced by
the surrounding environment. Roots frequently grow in heterogeneous environments
that include interactions from neighboring plants and physical impediments in
the rhizosphere. To investigate how planting density and physical objects affect
root system growth, we grew rice in a transparent gel system in close proximity
with another plant or a physical object. Root systems were imaged and reconstructed
in three dimensions. Root-root interaction strength was calculated using quantitative
metrics that characterize the extent towhich the reconstructed root systems overlap
each other. Surprisingly, we found the overlap of root systems of the same genotype
was significantly higher than that of root systems of different genotypes. Root
systems of the same genotype tended to grow toward each other but those of different
genotypes appeared to avoid each other. Shoot separation experiments excluded
the possibility of aerial interactions, suggesting root communication. Staggered
plantings indicated that interactions likely occur at root tips in close proximity.
Recognition of obstacles also occurred through root tips, but through physical
contact in a size-dependent manner. These results indicate that root systems use
two different forms of communication to recognize objects and alter root architecture:
root-root recognition, possibly mediated through root exudates, and root-object
recognition mediated by physical contact at the root tips. This finding suggests
that root tips act as local sensors that integrate rhizosphere information into
global root architectural changes.'
article_processing_charge: No
article_type: original
author:
- first_name: Suqin
full_name: Fang, Suqin
last_name: Fang
- first_name: Randy
full_name: Clark, Randy
last_name: Clark
- first_name: Ying
full_name: Zheng, Ying
last_name: Zheng
- first_name: Anjali
full_name: Iyer Pascuzzi, Anjali
last_name: Iyer Pascuzzi
- first_name: Joshua
full_name: Weitz, Joshua
last_name: Weitz
- first_name: Leon
full_name: Kochian, Leon
last_name: Kochian
- first_name: Herbert
full_name: Edelsbrunner, Herbert
id: 3FB178DA-F248-11E8-B48F-1D18A9856A87
last_name: Edelsbrunner
orcid: 0000-0002-9823-6833
- first_name: Hong
full_name: Liao, Hong
last_name: Liao
- first_name: Philip
full_name: Benfey, Philip
last_name: Benfey
citation:
ama: Fang S, Clark R, Zheng Y, et al. Genotypic recognition and spatial responses
by rice roots. PNAS. 2013;110(7):2670-2675. doi:10.1073/pnas.1222821110
apa: Fang, S., Clark, R., Zheng, Y., Iyer Pascuzzi, A., Weitz, J., Kochian, L.,
… Benfey, P. (2013). Genotypic recognition and spatial responses by rice roots.
PNAS. National Academy of Sciences. https://doi.org/10.1073/pnas.1222821110
chicago: Fang, Suqin, Randy Clark, Ying Zheng, Anjali Iyer Pascuzzi, Joshua Weitz,
Leon Kochian, Herbert Edelsbrunner, Hong Liao, and Philip Benfey. “Genotypic Recognition
and Spatial Responses by Rice Roots.” PNAS. National Academy of Sciences,
2013. https://doi.org/10.1073/pnas.1222821110.
ieee: S. Fang et al., “Genotypic recognition and spatial responses by rice
roots,” PNAS, vol. 110, no. 7. National Academy of Sciences, pp. 2670–2675,
2013.
ista: Fang S, Clark R, Zheng Y, Iyer Pascuzzi A, Weitz J, Kochian L, Edelsbrunner
H, Liao H, Benfey P. 2013. Genotypic recognition and spatial responses by rice
roots. PNAS. 110(7), 2670–2675.
mla: Fang, Suqin, et al. “Genotypic Recognition and Spatial Responses by Rice Roots.”
PNAS, vol. 110, no. 7, National Academy of Sciences, 2013, pp. 2670–75,
doi:10.1073/pnas.1222821110.
short: S. Fang, R. Clark, Y. Zheng, A. Iyer Pascuzzi, J. Weitz, L. Kochian, H. Edelsbrunner,
H. Liao, P. Benfey, PNAS 110 (2013) 2670–2675.
date_created: 2018-12-11T12:00:09Z
date_published: 2013-02-12T00:00:00Z
date_updated: 2021-01-12T07:00:29Z
day: '12'
department:
- _id: HeEd
doi: 10.1073/pnas.1222821110
external_id:
pmid:
- '23362379'
intvolume: ' 110'
issue: '7'
language:
- iso: eng
main_file_link:
- open_access: '1'
url: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3574932/
month: '02'
oa: 1
oa_version: Published Version
page: 2670 - 2675
pmid: 1
publication: PNAS
publication_status: published
publisher: National Academy of Sciences
publist_id: '3872'
quality_controlled: '1'
scopus_import: 1
status: public
title: Genotypic recognition and spatial responses by rice roots
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 110
year: '2013'
...
---
_id: '2901'
abstract:
- lang: eng
text: ' We introduce the M-modes problem for graphical models: predicting the M
label configurations of highest probability that are at the same time local maxima
of the probability landscape. M-modes have multiple possible applications: because
they are intrinsically diverse, they provide a principled alternative to non-maximum
suppression techniques for structured prediction, they can act as codebook vectors
for quantizing the configuration space, or they can form component centers for
mixture model approximation. We present two algorithms for solving the M-modes
problem. The first algorithm solves the problem in polynomial time when the underlying
graphical model is a simple chain. The second algorithm solves the problem for
junction chains. In synthetic and real dataset, we demonstrate how M-modes can
improve the performance of prediction. We also use the generated modes as a tool
to understand the topography of the probability distribution of configurations,
for example with relation to the training set size and amount of noise in the
data. '
alternative_title:
- ' JMLR: W&CP'
author:
- first_name: Chao
full_name: Chen, Chao
id: 3E92416E-F248-11E8-B48F-1D18A9856A87
last_name: Chen
- first_name: Vladimir
full_name: Kolmogorov, Vladimir
id: 3D50B0BA-F248-11E8-B48F-1D18A9856A87
last_name: Kolmogorov
- first_name: Zhu
full_name: Yan, Zhu
last_name: Yan
- first_name: Dimitris
full_name: Metaxas, Dimitris
last_name: Metaxas
- first_name: Christoph
full_name: Lampert, Christoph
id: 40C20FD2-F248-11E8-B48F-1D18A9856A87
last_name: Lampert
orcid: 0000-0001-8622-7887
citation:
ama: 'Chen C, Kolmogorov V, Yan Z, Metaxas D, Lampert C. Computing the M most probable
modes of a graphical model. In: Vol 31. JMLR; 2013:161-169.'
apa: 'Chen, C., Kolmogorov, V., Yan, Z., Metaxas, D., & Lampert, C. (2013).
Computing the M most probable modes of a graphical model (Vol. 31, pp. 161–169).
Presented at the AISTATS: Conference on Uncertainty in Artificial Intelligence,
Scottsdale, AZ, United States: JMLR.'
chicago: Chen, Chao, Vladimir Kolmogorov, Zhu Yan, Dimitris Metaxas, and Christoph
Lampert. “Computing the M Most Probable Modes of a Graphical Model,” 31:161–69.
JMLR, 2013.
ieee: 'C. Chen, V. Kolmogorov, Z. Yan, D. Metaxas, and C. Lampert, “Computing the
M most probable modes of a graphical model,” presented at the AISTATS: Conference
on Uncertainty in Artificial Intelligence, Scottsdale, AZ, United States, 2013,
vol. 31, pp. 161–169.'
ista: 'Chen C, Kolmogorov V, Yan Z, Metaxas D, Lampert C. 2013. Computing the M
most probable modes of a graphical model. AISTATS: Conference on Uncertainty
in Artificial Intelligence, JMLR: W&CP, vol. 31, 161–169.'
mla: Chen, Chao, et al. Computing the M Most Probable Modes of a Graphical Model.
Vol. 31, JMLR, 2013, pp. 161–69.
short: C. Chen, V. Kolmogorov, Z. Yan, D. Metaxas, C. Lampert, in:, JMLR, 2013,
pp. 161–169.
conference:
end_date: 2013-05-01
location: Scottsdale, AZ, United States
name: ' AISTATS: Conference on Uncertainty in Artificial Intelligence'
start_date: 2013-04-29
date_created: 2018-12-11T12:00:14Z
date_published: 2013-01-01T00:00:00Z
date_updated: 2021-01-12T07:00:35Z
day: '01'
department:
- _id: HeEd
- _id: VlKo
- _id: ChLa
intvolume: ' 31'
language:
- iso: eng
main_file_link:
- open_access: '1'
url: http://jmlr.org/proceedings/papers/v31/chen13a.html
month: '01'
oa: 1
oa_version: None
page: 161 - 169
publication_status: published
publisher: JMLR
publist_id: '3846'
quality_controlled: '1'
scopus_import: 1
status: public
title: Computing the M most probable modes of a graphical model
type: conference
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 31
year: '2013'
...