---
_id: '1934'
abstract:
- lang: eng
text: The plant hormones auxin and cytokinin mutually coordinate their activities
to control various aspects of development [1-9], and their crosstalk occurs at
multiple levels [10, 11]. Cytokinin-mediated modulation of auxin transport provides
an efficient means to regulate auxin distribution in plant organs. Here, we demonstrate
that cytokinin does not merely control the overall auxin flow capacity, but might
also act as a polarizing cue and control the auxin stream directionality during
plant organogenesis. Cytokinin enhances the PIN-FORMED1 (PIN1) auxin transporter
depletion at specific polar domains, thus rearranging the cellular PIN polarities
and directly regulating the auxin flow direction. This selective cytokinin sensitivity
correlates with the PIN protein phosphorylation degree. PIN1 phosphomimicking
mutations, as well as enhanced phosphorylation in plants with modulated activities
of PIN-specific kinases and phosphatases, desensitize PIN1 to cytokinin. Our results
reveal conceptually novel, cytokinin-driven polarization mechanism that operates
in developmental processes involving rapid auxin stream redirection, such as lateral
root organogenesis, in which a gradual PIN polarity switch defines the growth
axis of the newly formed organ.
author:
- first_name: Peter
full_name: Marhavy, Peter
id: 3F45B078-F248-11E8-B48F-1D18A9856A87
last_name: Marhavy
orcid: 0000-0001-5227-5741
- first_name: Jérôme
full_name: Duclercq, Jérôme
last_name: Duclercq
- first_name: Benjamin
full_name: Weller, Benjamin
last_name: Weller
- first_name: Elena
full_name: Feraru, Elena
last_name: Feraru
- first_name: Agnieszka
full_name: Bielach, Agnieszka
last_name: Bielach
- first_name: Remko
full_name: Offringa, Remko
last_name: Offringa
- first_name: Jirí
full_name: Friml, Jirí
id: 4159519E-F248-11E8-B48F-1D18A9856A87
last_name: Friml
orcid: 0000-0002-8302-7596
- first_name: Claus
full_name: Schwechheimer, Claus
last_name: Schwechheimer
- first_name: Angus
full_name: Murphy, Angus
last_name: Murphy
- first_name: Eva
full_name: Benková, Eva
id: 38F4F166-F248-11E8-B48F-1D18A9856A87
last_name: Benková
orcid: 0000-0002-8510-9739
citation:
ama: Marhavý P, Duclercq J, Weller B, et al. Cytokinin controls polarity of PIN1-dependent
Auxin transport during lateral root organogenesis. Current Biology. 2014;24(9):1031-1037.
doi:10.1016/j.cub.2014.04.002
apa: Marhavý, P., Duclercq, J., Weller, B., Feraru, E., Bielach, A., Offringa, R.,
… Benková, E. (2014). Cytokinin controls polarity of PIN1-dependent Auxin transport
during lateral root organogenesis. Current Biology. Cell Press. https://doi.org/10.1016/j.cub.2014.04.002
chicago: Marhavý, Peter, Jérôme Duclercq, Benjamin Weller, Elena Feraru, Agnieszka
Bielach, Remko Offringa, Jiří Friml, Claus Schwechheimer, Angus Murphy, and Eva
Benková. “Cytokinin Controls Polarity of PIN1-Dependent Auxin Transport during
Lateral Root Organogenesis.” Current Biology. Cell Press, 2014. https://doi.org/10.1016/j.cub.2014.04.002.
ieee: P. Marhavý et al., “Cytokinin controls polarity of PIN1-dependent Auxin
transport during lateral root organogenesis,” Current Biology, vol. 24,
no. 9. Cell Press, pp. 1031–1037, 2014.
ista: Marhavý P, Duclercq J, Weller B, Feraru E, Bielach A, Offringa R, Friml J,
Schwechheimer C, Murphy A, Benková E. 2014. Cytokinin controls polarity of PIN1-dependent
Auxin transport during lateral root organogenesis. Current Biology. 24(9), 1031–1037.
mla: Marhavý, Peter, et al. “Cytokinin Controls Polarity of PIN1-Dependent Auxin
Transport during Lateral Root Organogenesis.” Current Biology, vol. 24,
no. 9, Cell Press, 2014, pp. 1031–37, doi:10.1016/j.cub.2014.04.002.
short: P. Marhavý, J. Duclercq, B. Weller, E. Feraru, A. Bielach, R. Offringa, J.
Friml, C. Schwechheimer, A. Murphy, E. Benková, Current Biology 24 (2014) 1031–1037.
date_created: 2018-12-11T11:54:48Z
date_published: 2014-05-05T00:00:00Z
date_updated: 2021-01-12T06:54:10Z
day: '05'
department:
- _id: EvBe
- _id: JiFr
doi: 10.1016/j.cub.2014.04.002
ec_funded: 1
intvolume: ' 24'
issue: '9'
language:
- iso: eng
month: '05'
oa_version: None
page: 1031 - 1037
project:
- _id: 253FCA6A-B435-11E9-9278-68D0E5697425
call_identifier: FP7
grant_number: '207362'
name: Hormonal cross-talk in plant organogenesis
publication: Current Biology
publication_status: published
publisher: Cell Press
publist_id: '5160'
quality_controlled: '1'
scopus_import: 1
status: public
title: Cytokinin controls polarity of PIN1-dependent Auxin transport during lateral
root organogenesis
type: journal_article
user_id: 4435EBFC-F248-11E8-B48F-1D18A9856A87
volume: 24
year: '2014'
...
---
_id: '1932'
abstract:
- lang: eng
text: The existence of complex (multiple-step) genetic adaptations that are "irreducible"
(i.e., all partial combinations are less fit than the original genotype) is one
of the longest standing problems in evolutionary biology. In standard genetics
parlance, these adaptations require the crossing of a wide adaptive valley of
deleterious intermediate stages. Here, we demonstrate, using a simple model, that
evolution can cross wide valleys to produce "irreducibly complex" adaptations
by making use of previously cryptic mutations. When revealed by an evolutionary
capacitor, previously cryptic mutants have higher initial frequencies than do
new mutations, bringing them closer to a valley-crossing saddle in allele frequency
space. Moreover, simple combinatorics implies an enormous number of candidate
combinations exist within available cryptic genetic variation. We model the dynamics
of crossing of a wide adaptive valley after a capacitance event using both numerical
simulations and analytical approximations. Although individual valley crossing
events become less likely as valleys widen, by taking the combinatorics of genotype
space into account, we see that revealing cryptic variation can cause the frequent
evolution of complex adaptations.
acknowledgement: "Funded by National Institutes of Health. Grant Numbers: R01GM076041,
R01GM104040 \r\n\r\nSimons Foundation\r\n\r\n"
author:
- first_name: Meredith
full_name: Trotter, Meredith
last_name: Trotter
- first_name: Daniel
full_name: Weissman, Daniel
id: 2D0CE020-F248-11E8-B48F-1D18A9856A87
last_name: Weissman
- first_name: Grant
full_name: Peterson, Grant
last_name: Peterson
- first_name: Kayla
full_name: Peck, Kayla
last_name: Peck
- first_name: Joanna
full_name: Masel, Joanna
last_name: Masel
citation:
ama: Trotter M, Weissman D, Peterson G, Peck K, Masel J. Cryptic genetic variation
can make "irreducible complexity" a common mode of adaptation
in sexual populations. Evolution. 2014;68(12):3357-3367. doi:10.1111/evo.12517
apa: Trotter, M., Weissman, D., Peterson, G., Peck, K., & Masel, J. (2014).
Cryptic genetic variation can make "irreducible complexity"
a common mode of adaptation in sexual populations. Evolution. Wiley-Blackwell.
https://doi.org/10.1111/evo.12517
chicago: Trotter, Meredith, Daniel Weissman, Grant Peterson, Kayla Peck, and Joanna
Masel. “Cryptic Genetic Variation Can Make "Irreducible Complexity"
a Common Mode of Adaptation in Sexual Populations.” Evolution. Wiley-Blackwell,
2014. https://doi.org/10.1111/evo.12517.
ieee: M. Trotter, D. Weissman, G. Peterson, K. Peck, and J. Masel, “Cryptic genetic
variation can make "irreducible complexity" a common mode of
adaptation in sexual populations,” Evolution, vol. 68, no. 12. Wiley-Blackwell,
pp. 3357–3367, 2014.
ista: Trotter M, Weissman D, Peterson G, Peck K, Masel J. 2014. Cryptic genetic
variation can make "irreducible complexity" a common mode of
adaptation in sexual populations. Evolution. 68(12), 3357–3367.
mla: Trotter, Meredith, et al. “Cryptic Genetic Variation Can Make "Irreducible
Complexity" a Common Mode of Adaptation in Sexual Populations.” Evolution,
vol. 68, no. 12, Wiley-Blackwell, 2014, pp. 3357–67, doi:10.1111/evo.12517.
short: M. Trotter, D. Weissman, G. Peterson, K. Peck, J. Masel, Evolution 68 (2014)
3357–3367.
date_created: 2018-12-11T11:54:47Z
date_published: 2014-12-01T00:00:00Z
date_updated: 2021-01-12T06:54:10Z
day: '01'
department:
- _id: NiBa
doi: 10.1111/evo.12517
ec_funded: 1
intvolume: ' 68'
issue: '12'
language:
- iso: eng
main_file_link:
- open_access: '1'
url: http://arxiv.org/abs/1310.6077
month: '12'
oa: 1
oa_version: Submitted Version
page: 3357 - 3367
project:
- _id: 25B07788-B435-11E9-9278-68D0E5697425
call_identifier: FP7
grant_number: '250152'
name: Limits to selection in biology and in evolutionary computation
publication: Evolution
publication_status: published
publisher: Wiley-Blackwell
publist_id: '5162'
quality_controlled: '1'
scopus_import: 1
status: public
title: Cryptic genetic variation can make "irreducible complexity" a common
mode of adaptation in sexual populations
type: journal_article
user_id: 4435EBFC-F248-11E8-B48F-1D18A9856A87
volume: 68
year: '2014'
...
---
_id: '1930'
abstract:
- lang: eng
text: (Figure Presented) Data acquisition, numerical inaccuracies, and sampling
often introduce noise in measurements and simulations. Removing this noise is
often necessary for efficient analysis and visualization of this data, yet many
denoising techniques change the minima and maxima of a scalar field. For example,
the extrema can appear or disappear, spatially move, and change their value. This
can lead to wrong interpretations of the data, e.g., when the maximum temperature
over an area is falsely reported being a few degrees cooler because the denoising
method is unaware of these features. Recently, a topological denoising technique
based on a global energy optimization was proposed, which allows the topology-controlled
denoising of 2D scalar fields. While this method preserves the minima and maxima,
it is constrained by the size of the data. We extend this work to large 2D data
and medium-sized 3D data by introducing a novel domain decomposition approach.
It allows processing small patches of the domain independently while still avoiding
the introduction of new critical points. Furthermore, we propose an iterative
refinement of the solution, which decreases the optimization energy compared to
the previous approach and therefore gives smoother results that are closer to
the input. We illustrate our technique on synthetic and real-world 2D and 3D data
sets that highlight potential applications.
acknowledgement: RTRA Digiteoproject; ERC grant; SNF award; Intel Doctoral Fellowship;
MPC-VCC
author:
- first_name: David
full_name: Günther, David
last_name: Günther
- first_name: Alec
full_name: Jacobson, Alec
last_name: Jacobson
- first_name: Jan
full_name: Reininghaus, Jan
id: 4505473A-F248-11E8-B48F-1D18A9856A87
last_name: Reininghaus
- first_name: Hans
full_name: Seidel, Hans
last_name: Seidel
- first_name: Olga
full_name: Sorkine Hornung, Olga
last_name: Sorkine Hornung
- first_name: Tino
full_name: Weinkauf, Tino
last_name: Weinkauf
citation:
ama: Günther D, Jacobson A, Reininghaus J, Seidel H, Sorkine Hornung O, Weinkauf
T. Fast and memory-efficient topological denoising of 2D and 3D scalar fields.
IEEE Transactions on Visualization and Computer Graphics. 2014;20(12):2585-2594.
doi:10.1109/TVCG.2014.2346432
apa: Günther, D., Jacobson, A., Reininghaus, J., Seidel, H., Sorkine Hornung, O.,
& Weinkauf, T. (2014). Fast and memory-efficient topological denoising of
2D and 3D scalar fields. IEEE Transactions on Visualization and Computer Graphics.
IEEE. https://doi.org/10.1109/TVCG.2014.2346432
chicago: Günther, David, Alec Jacobson, Jan Reininghaus, Hans Seidel, Olga Sorkine
Hornung, and Tino Weinkauf. “Fast and Memory-Efficient Topological Denoising of
2D and 3D Scalar Fields.” IEEE Transactions on Visualization and Computer Graphics.
IEEE, 2014. https://doi.org/10.1109/TVCG.2014.2346432.
ieee: D. Günther, A. Jacobson, J. Reininghaus, H. Seidel, O. Sorkine Hornung, and
T. Weinkauf, “Fast and memory-efficient topological denoising of 2D and 3D scalar
fields,” IEEE Transactions on Visualization and Computer Graphics, vol.
20, no. 12. IEEE, pp. 2585–2594, 2014.
ista: Günther D, Jacobson A, Reininghaus J, Seidel H, Sorkine Hornung O, Weinkauf
T. 2014. Fast and memory-efficient topological denoising of 2D and 3D scalar fields.
IEEE Transactions on Visualization and Computer Graphics. 20(12), 2585–2594.
mla: Günther, David, et al. “Fast and Memory-Efficient Topological Denoising of
2D and 3D Scalar Fields.” IEEE Transactions on Visualization and Computer Graphics,
vol. 20, no. 12, IEEE, 2014, pp. 2585–94, doi:10.1109/TVCG.2014.2346432.
short: D. Günther, A. Jacobson, J. Reininghaus, H. Seidel, O. Sorkine Hornung, T.
Weinkauf, IEEE Transactions on Visualization and Computer Graphics 20 (2014) 2585–2594.
date_created: 2018-12-11T11:54:46Z
date_published: 2014-12-31T00:00:00Z
date_updated: 2021-01-12T06:54:09Z
day: '31'
department:
- _id: HeEd
doi: 10.1109/TVCG.2014.2346432
intvolume: ' 20'
issue: '12'
language:
- iso: eng
month: '12'
oa_version: None
page: 2585 - 2594
publication: IEEE Transactions on Visualization and Computer Graphics
publication_status: published
publisher: IEEE
publist_id: '5164'
quality_controlled: '1'
scopus_import: 1
status: public
title: Fast and memory-efficient topological denoising of 2D and 3D scalar fields
type: journal_article
user_id: 4435EBFC-F248-11E8-B48F-1D18A9856A87
volume: 20
year: '2014'
...
---
_id: '1933'
abstract:
- lang: eng
text: The development of the vertebrate brain requires an exquisite balance between
proliferation and differentiation of neural progenitors. Notch signaling plays
a pivotal role in regulating this balance, yet the interaction between signaling
and receiving cells remains poorly understood. We have found that numerous nascent
neurons and/or intermediate neurogenic progenitors expressing the ligand of Notch
retain apical endfeet transiently at the ventricular lumen that form adherens
junctions (AJs) with the endfeet of progenitors. Forced detachment of the apical
endfeet of those differentiating cells by disrupting AJs resulted in precocious
neurogenesis that was preceded by the downregulation of Notch signaling. Both
Notch1 and its ligand Dll1 are distributed around AJs in the apical endfeet, and
these proteins physically interact with ZO-1, a constituent of the AJ. Furthermore,
live imaging of a fluorescently tagged Notch1 demonstrated its trafficking from
the apical endfoot to the nucleus upon cleavage. Our results identified the apical
endfoot as the central site of active Notch signaling to securely prohibit inappropriate
differentiation of neural progenitors.
author:
- first_name: Jun
full_name: Hatakeyama, Jun
last_name: Hatakeyama
- first_name: Yoshio
full_name: Wakamatsu, Yoshio
last_name: Wakamatsu
- first_name: Akira
full_name: Nagafuchi, Akira
last_name: Nagafuchi
- first_name: Ryoichiro
full_name: Kageyama, Ryoichiro
last_name: Kageyama
- first_name: Ryuichi
full_name: Shigemoto, Ryuichi
id: 499F3ABC-F248-11E8-B48F-1D18A9856A87
last_name: Shigemoto
orcid: 0000-0001-8761-9444
- first_name: Kenji
full_name: Shimamura, Kenji
last_name: Shimamura
citation:
ama: Hatakeyama J, Wakamatsu Y, Nagafuchi A, Kageyama R, Shigemoto R, Shimamura
K. Cadherin-based adhesions in the apical endfoot are required for active Notch
signaling to control neurogenesis in vertebrates. Development. 2014;141(8):1671-1682.
doi:10.1242/dev.102988
apa: Hatakeyama, J., Wakamatsu, Y., Nagafuchi, A., Kageyama, R., Shigemoto, R.,
& Shimamura, K. (2014). Cadherin-based adhesions in the apical endfoot are
required for active Notch signaling to control neurogenesis in vertebrates. Development.
Company of Biologists. https://doi.org/10.1242/dev.102988
chicago: Hatakeyama, Jun, Yoshio Wakamatsu, Akira Nagafuchi, Ryoichiro Kageyama,
Ryuichi Shigemoto, and Kenji Shimamura. “Cadherin-Based Adhesions in the Apical
Endfoot Are Required for Active Notch Signaling to Control Neurogenesis in Vertebrates.”
Development. Company of Biologists, 2014. https://doi.org/10.1242/dev.102988.
ieee: J. Hatakeyama, Y. Wakamatsu, A. Nagafuchi, R. Kageyama, R. Shigemoto, and
K. Shimamura, “Cadherin-based adhesions in the apical endfoot are required for
active Notch signaling to control neurogenesis in vertebrates,” Development,
vol. 141, no. 8. Company of Biologists, pp. 1671–1682, 2014.
ista: Hatakeyama J, Wakamatsu Y, Nagafuchi A, Kageyama R, Shigemoto R, Shimamura
K. 2014. Cadherin-based adhesions in the apical endfoot are required for active
Notch signaling to control neurogenesis in vertebrates. Development. 141(8), 1671–1682.
mla: Hatakeyama, Jun, et al. “Cadherin-Based Adhesions in the Apical Endfoot Are
Required for Active Notch Signaling to Control Neurogenesis in Vertebrates.” Development,
vol. 141, no. 8, Company of Biologists, 2014, pp. 1671–82, doi:10.1242/dev.102988.
short: J. Hatakeyama, Y. Wakamatsu, A. Nagafuchi, R. Kageyama, R. Shigemoto, K.
Shimamura, Development 141 (2014) 1671–1682.
date_created: 2018-12-11T11:54:47Z
date_published: 2014-04-01T00:00:00Z
date_updated: 2021-01-12T06:54:10Z
day: '01'
department:
- _id: RySh
doi: 10.1242/dev.102988
intvolume: ' 141'
issue: '8'
language:
- iso: eng
month: '04'
oa_version: None
page: 1671 - 1682
publication: Development
publication_status: published
publisher: Company of Biologists
publist_id: '5161'
quality_controlled: '1'
scopus_import: 1
status: public
title: Cadherin-based adhesions in the apical endfoot are required for active Notch
signaling to control neurogenesis in vertebrates
type: journal_article
user_id: 4435EBFC-F248-11E8-B48F-1D18A9856A87
volume: 141
year: '2014'
...
---
_id: '1931'
abstract:
- lang: eng
text: A wealth of experimental evidence suggests that working memory circuits preferentially
represent information that is behaviorally relevant. Still, we are missing a mechanistic
account of how these representations come about. Here we provide a simple explanation
for a range of experimental findings, in light of prefrontal circuits adapting
to task constraints by reward-dependent learning. In particular, we model a neural
network shaped by reward-modulated spike-timing dependent plasticity (r-STDP)
and homeostatic plasticity (intrinsic excitability and synaptic scaling). We show
that the experimentally-observed neural representations naturally emerge in an
initially unstructured circuit as it learns to solve several working memory tasks.
These results point to a critical, and previously unappreciated, role for reward-dependent
learning in shaping prefrontal cortex activity.
acknowledgement: Supported in part by EC MEXT project PLICON and the LOEWE-Program
“Neuronal Coordination Research Focus Frankfurt” (NeFF). Jochen Triesch was supported
by the Quandt foundation.
article_number: '57'
author:
- first_name: Cristina
full_name: Savin, Cristina
id: 3933349E-F248-11E8-B48F-1D18A9856A87
last_name: Savin
- first_name: Jochen
full_name: Triesch, Jochen
last_name: Triesch
citation:
ama: Savin C, Triesch J. Emergence of task-dependent representations in working
memory circuits. Frontiers in Computational Neuroscience. 2014;8(MAY).
doi:10.3389/fncom.2014.00057
apa: Savin, C., & Triesch, J. (2014). Emergence of task-dependent representations
in working memory circuits. Frontiers in Computational Neuroscience. Frontiers
Research Foundation. https://doi.org/10.3389/fncom.2014.00057
chicago: Savin, Cristina, and Jochen Triesch. “Emergence of Task-Dependent Representations
in Working Memory Circuits.” Frontiers in Computational Neuroscience. Frontiers
Research Foundation, 2014. https://doi.org/10.3389/fncom.2014.00057.
ieee: C. Savin and J. Triesch, “Emergence of task-dependent representations in working
memory circuits,” Frontiers in Computational Neuroscience, vol. 8, no.
MAY. Frontiers Research Foundation, 2014.
ista: Savin C, Triesch J. 2014. Emergence of task-dependent representations in working
memory circuits. Frontiers in Computational Neuroscience. 8(MAY), 57.
mla: Savin, Cristina, and Jochen Triesch. “Emergence of Task-Dependent Representations
in Working Memory Circuits.” Frontiers in Computational Neuroscience, vol.
8, no. MAY, 57, Frontiers Research Foundation, 2014, doi:10.3389/fncom.2014.00057.
short: C. Savin, J. Triesch, Frontiers in Computational Neuroscience 8 (2014).
date_created: 2018-12-11T11:54:46Z
date_published: 2014-05-28T00:00:00Z
date_updated: 2021-01-12T06:54:09Z
day: '28'
department:
- _id: GaTk
doi: 10.3389/fncom.2014.00057
intvolume: ' 8'
issue: MAY
language:
- iso: eng
main_file_link:
- open_access: '1'
url: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4035833/
month: '05'
oa: 1
oa_version: Submitted Version
publication: Frontiers in Computational Neuroscience
publication_status: published
publisher: Frontiers Research Foundation
publist_id: '5163'
quality_controlled: '1'
scopus_import: 1
status: public
title: Emergence of task-dependent representations in working memory circuits
type: journal_article
user_id: 4435EBFC-F248-11E8-B48F-1D18A9856A87
volume: 8
year: '2014'
...
---
_id: '1937'
abstract:
- lang: eng
text: We prove the edge universality of the beta ensembles for any β ≥ 1, provided
that the limiting spectrum is supported on a single interval, and the external
potential is C4 and regular. We also prove that the edge universality holds for
generalized Wigner matrices for all symmetry classes. Moreover, our results allow
us to extend bulk universality for beta ensembles from analytic potentials to
potentials in class C4.
author:
- first_name: Paul
full_name: Bourgade, Paul
last_name: Bourgade
- first_name: László
full_name: Erdös, László
id: 4DBD5372-F248-11E8-B48F-1D18A9856A87
last_name: Erdös
orcid: 0000-0001-5366-9603
- first_name: Horngtzer
full_name: Yau, Horngtzer
last_name: Yau
citation:
ama: Bourgade P, Erdös L, Yau H. Edge universality of beta ensembles. Communications
in Mathematical Physics. 2014;332(1):261-353. doi:10.1007/s00220-014-2120-z
apa: Bourgade, P., Erdös, L., & Yau, H. (2014). Edge universality of beta ensembles.
Communications in Mathematical Physics. Springer. https://doi.org/10.1007/s00220-014-2120-z
chicago: Bourgade, Paul, László Erdös, and Horngtzer Yau. “Edge Universality of
Beta Ensembles.” Communications in Mathematical Physics. Springer, 2014.
https://doi.org/10.1007/s00220-014-2120-z.
ieee: P. Bourgade, L. Erdös, and H. Yau, “Edge universality of beta ensembles,”
Communications in Mathematical Physics, vol. 332, no. 1. Springer, pp.
261–353, 2014.
ista: Bourgade P, Erdös L, Yau H. 2014. Edge universality of beta ensembles. Communications
in Mathematical Physics. 332(1), 261–353.
mla: Bourgade, Paul, et al. “Edge Universality of Beta Ensembles.” Communications
in Mathematical Physics, vol. 332, no. 1, Springer, 2014, pp. 261–353, doi:10.1007/s00220-014-2120-z.
short: P. Bourgade, L. Erdös, H. Yau, Communications in Mathematical Physics 332
(2014) 261–353.
date_created: 2018-12-11T11:54:48Z
date_published: 2014-11-01T00:00:00Z
date_updated: 2021-01-12T06:54:12Z
day: '01'
department:
- _id: LaEr
doi: 10.1007/s00220-014-2120-z
intvolume: ' 332'
issue: '1'
language:
- iso: eng
main_file_link:
- open_access: '1'
url: http://arxiv.org/abs/1306.5728
month: '11'
oa: 1
oa_version: Submitted Version
page: 261 - 353
project:
- _id: 25BDE9A4-B435-11E9-9278-68D0E5697425
grant_number: SFB-TR3-TP10B
name: Glutamaterge synaptische Übertragung und Plastizität in hippocampalen Mikroschaltkreisen
publication: Communications in Mathematical Physics
publication_status: published
publisher: Springer
publist_id: '5158'
quality_controlled: '1'
scopus_import: 1
status: public
title: Edge universality of beta ensembles
type: journal_article
user_id: 4435EBFC-F248-11E8-B48F-1D18A9856A87
volume: 332
year: '2014'
...
---
_id: '1981'
abstract:
- lang: eng
text: Variation in mitochondrial DNA is often assumed to be neutral and is used
to construct the genealogical relationships among populations and species. However,
if extant variation is the result of episodes of positive selection, these genealogies
may be incorrect, although this information itself may provide biologically and
evolutionary meaningful information. In fact, positive Darwinian selection has
been detected in the mitochondrial-encoded subunits that comprise complex I from
diverse taxa with seemingly dissimilar bioenergetic life histories, but the functional
implications of the selected sites are unknown. Complex I produces roughly 40%
of the proton flux that is used to synthesize ATP from ADP, and a functional model
based on the high-resolution structure of complex I described a unique biomechanical
apparatus for proton translocation. We reported positive selection at sites in
this apparatus during the evolution of Pacific salmon, and it appeared this was
also the case in published reports from other taxa, but a comparison among studies
was difficult because different statistical tests were used to detect selection
and oftentimes, specific sites were not reported. Here we review the literature
of positive selection in mitochondrial genomes, the statistical tests used to
detect selection, and the structural and functional models that are currently
available to study the physiological implications of selection. We then search
for signatures of positive selection among the coding mitochondrial genomes of
237 species with a common set of tests and verify that the ND5 subunit of complex
I is a repeated target of positive Darwinian selection in diverse taxa. We propose
a novel hypothesis to explain the results based on their bioenergetic life histories
and provide a guide for laboratory and field studies to test this hypothesis.
acknowledgement: Funded by University of Alaska Center for Global Change Student
Research Cooperative Institute for Alaska Research and the Rasmuson Foundation
author:
- first_name: Michael
full_name: Garvin, Michael R
last_name: Garvin
- first_name: Joseph
full_name: Bielawski, Joseph P
last_name: Bielawski
- first_name: Leonid A
full_name: Leonid Sazanov
id: 338D39FE-F248-11E8-B48F-1D18A9856A87
last_name: Sazanov
orcid: 0000-0002-0977-7989
- first_name: Anthony
full_name: Gharrett, Anthony J
last_name: Gharrett
citation:
ama: Garvin M, Bielawski J, Sazanov LA, Gharrett A. Review and meta-analysis of
natural selection in mitochondrial complex I in metazoans. Journal of Zoological
Systematics and Evolutionary Research. 2014;53(1):1-17. doi:10.1111/jzs.12079
apa: Garvin, M., Bielawski, J., Sazanov, L. A., & Gharrett, A. (2014). Review
and meta-analysis of natural selection in mitochondrial complex I in metazoans.
Journal of Zoological Systematics and Evolutionary Research. Wiley-Blackwell.
https://doi.org/10.1111/jzs.12079
chicago: Garvin, Michael, Joseph Bielawski, Leonid A Sazanov, and Anthony Gharrett.
“Review and Meta-Analysis of Natural Selection in Mitochondrial Complex I in Metazoans.”
Journal of Zoological Systematics and Evolutionary Research. Wiley-Blackwell,
2014. https://doi.org/10.1111/jzs.12079.
ieee: M. Garvin, J. Bielawski, L. A. Sazanov, and A. Gharrett, “Review and meta-analysis
of natural selection in mitochondrial complex I in metazoans,” Journal of Zoological
Systematics and Evolutionary Research, vol. 53, no. 1. Wiley-Blackwell, pp.
1–17, 2014.
ista: Garvin M, Bielawski J, Sazanov LA, Gharrett A. 2014. Review and meta-analysis
of natural selection in mitochondrial complex I in metazoans. Journal of Zoological
Systematics and Evolutionary Research. 53(1), 1–17.
mla: Garvin, Michael, et al. “Review and Meta-Analysis of Natural Selection in Mitochondrial
Complex I in Metazoans.” Journal of Zoological Systematics and Evolutionary
Research, vol. 53, no. 1, Wiley-Blackwell, 2014, pp. 1–17, doi:10.1111/jzs.12079.
short: M. Garvin, J. Bielawski, L.A. Sazanov, A. Gharrett, Journal of Zoological
Systematics and Evolutionary Research 53 (2014) 1–17.
date_created: 2018-12-11T11:55:02Z
date_published: 2014-02-01T00:00:00Z
date_updated: 2019-04-26T07:22:06Z
day: '01'
doi: 10.1111/jzs.12079
extern: 1
intvolume: ' 53'
issue: '1'
month: '02'
page: 1 - 17
publication: Journal of Zoological Systematics and Evolutionary Research
publication_status: published
publisher: Wiley-Blackwell
publist_id: '5102'
quality_controlled: 0
status: public
title: Review and meta-analysis of natural selection in mitochondrial complex I in
metazoans
type: review
volume: 53
year: '2014'
...
---
_id: '1980'
abstract:
- lang: eng
text: Non-proton pumping type II NADH dehydrogenase (NDH-2) plays a central role
in the respiratory metabolism of bacteria, and in the mitochondria of fungi, plants
and protists. The lack of NDH-2 in mammalian mitochondria and its essentiality
in important bacterial pathogens suggests these enzymes may represent a potential
new drug target to combat microbial pathogens. Here, we report the first crystal
structure of a bacterial NDH-2 enzyme at 2.5Å resolution from Caldalkalibacillus
thermarum. The NDH-2 structure reveals a homodimeric organization that has a unique
dimer interface. NDH-2 is localized to the cytoplasmic membrane by two separated
C-terminal membrane-anchoring regions that are essential for membrane localization
and FAD binding, but not NDH-2 dimerization. Comparison of bacterial NDH-2 with
the yeast NADH dehydrogenase (Ndi1) structure revealed non-overlapping binding
sites for quinone and NADH in the bacterial enzyme. The bacterial NDH-2 structure
establishes a framework for the structure-based design of small-molecule inhibitors.
acknowledgement: Funded by Health Research Council of New Zealand Royal Society
of New Zealand University of Otago New Zealand Synchrotron Group
author:
- first_name: Adam
full_name: 'Heikal, Adam '
last_name: Heikal
- first_name: Yoshio
full_name: Nakatani, Yoshio
last_name: Nakatani
- first_name: Elyse
full_name: Dunn, Elyse A
last_name: Dunn
- first_name: Marion
full_name: Weimar, Marion R
last_name: Weimar
- first_name: Catherine
full_name: Day, Catherine
last_name: Day
- first_name: Edward
full_name: Baker, Edward N
last_name: Baker
- first_name: Shaun
full_name: Lott, Shaun J
last_name: Lott
- first_name: Leonid A
full_name: Leonid Sazanov
id: 338D39FE-F248-11E8-B48F-1D18A9856A87
last_name: Sazanov
orcid: 0000-0002-0977-7989
- first_name: Gregory
full_name: Cook, Gregory
last_name: Cook
citation:
ama: 'Heikal A, Nakatani Y, Dunn E, et al. Structure of the bacterial type II NADH
dehydrogenase: a monotopic membrane protein with an essential role in energy generation.
Molecular Microbiology. 2014;91(5):950-964. doi:10.1111/mmi.12507'
apa: 'Heikal, A., Nakatani, Y., Dunn, E., Weimar, M., Day, C., Baker, E., … Cook,
G. (2014). Structure of the bacterial type II NADH dehydrogenase: a monotopic
membrane protein with an essential role in energy generation. Molecular Microbiology.
Wiley-Blackwell. https://doi.org/10.1111/mmi.12507'
chicago: 'Heikal, Adam, Yoshio Nakatani, Elyse Dunn, Marion Weimar, Catherine Day,
Edward Baker, Shaun Lott, Leonid A Sazanov, and Gregory Cook. “Structure of the
Bacterial Type II NADH Dehydrogenase: A Monotopic Membrane Protein with an Essential
Role in Energy Generation.” Molecular Microbiology. Wiley-Blackwell, 2014.
https://doi.org/10.1111/mmi.12507.'
ieee: 'A. Heikal et al., “Structure of the bacterial type II NADH dehydrogenase:
a monotopic membrane protein with an essential role in energy generation,” Molecular
Microbiology, vol. 91, no. 5. Wiley-Blackwell, pp. 950–964, 2014.'
ista: 'Heikal A, Nakatani Y, Dunn E, Weimar M, Day C, Baker E, Lott S, Sazanov LA,
Cook G. 2014. Structure of the bacterial type II NADH dehydrogenase: a monotopic
membrane protein with an essential role in energy generation. Molecular Microbiology.
91(5), 950–964.'
mla: 'Heikal, Adam, et al. “Structure of the Bacterial Type II NADH Dehydrogenase:
A Monotopic Membrane Protein with an Essential Role in Energy Generation.” Molecular
Microbiology, vol. 91, no. 5, Wiley-Blackwell, 2014, pp. 950–64, doi:10.1111/mmi.12507.'
short: A. Heikal, Y. Nakatani, E. Dunn, M. Weimar, C. Day, E. Baker, S. Lott, L.A.
Sazanov, G. Cook, Molecular Microbiology 91 (2014) 950–964.
date_created: 2018-12-11T11:55:01Z
date_published: 2014-03-01T00:00:00Z
date_updated: 2021-01-12T06:54:29Z
day: '01'
doi: 10.1111/mmi.12507
extern: 1
intvolume: ' 91'
issue: '5'
month: '03'
page: 950 - 964
publication: Molecular Microbiology
publication_status: published
publisher: Wiley-Blackwell
publist_id: '5103'
quality_controlled: 0
status: public
title: 'Structure of the bacterial type II NADH dehydrogenase: a monotopic membrane
protein with an essential role in energy generation'
type: journal_article
volume: 91
year: '2014'
...
---
_id: '1979'
abstract:
- lang: eng
text: NADH-ubiquinone oxidoreductase (complex I) is the first and largest enzyme
in the respiratory chain of mitochondria and many bacteria. It couples the transfer
of two electrons between NADH and ubiquinone to the translocation of four protons
across the membrane. Complex I is an L-shaped assembly formed by the hydrophilic
(peripheral) arm, containing all the redox centres performing electron transfer
and the membrane arm, containing proton-translocating machinery. Mitochondrial
complex I consists of 44 subunits of about 1 MDa in total, whilst the prokaryotic
enzyme is simpler and generally consists of 14 conserved “core” subunits. Recently
we have determined the first atomic structure of the entire complex I, using the
enzyme from Thermus thermophilus (536 kDa, 16 subunits, 9 Fe-S clusters, 64 TM
helices). Structure suggests a unique coupling mechanism, with redox energy of
electron transfer driving proton translocation via long-range (up to ~200 Å) conformational
changes. It resembles a steam engine, with coupling elements (akin to coupling
rods) linking parts of this molecular machine.
author:
- first_name: Leonid A
full_name: Leonid Sazanov
id: 338D39FE-F248-11E8-B48F-1D18A9856A87
last_name: Sazanov
orcid: 0000-0002-0977-7989
citation:
ama: Sazanov LA. The mechanism of coupling between electron transfer and proton
translocation in respiratory complex I. Journal of Bioenergetics and Biomembranes.
2014;46(4):247-253. doi:10.1007/s10863-014-9554-z
apa: Sazanov, L. A. (2014). The mechanism of coupling between electron transfer
and proton translocation in respiratory complex I. Journal of Bioenergetics
and Biomembranes. Springer. https://doi.org/10.1007/s10863-014-9554-z
chicago: Sazanov, Leonid A. “The Mechanism of Coupling between Electron Transfer
and Proton Translocation in Respiratory Complex I.” Journal of Bioenergetics
and Biomembranes. Springer, 2014. https://doi.org/10.1007/s10863-014-9554-z.
ieee: L. A. Sazanov, “The mechanism of coupling between electron transfer and proton
translocation in respiratory complex I,” Journal of Bioenergetics and Biomembranes,
vol. 46, no. 4. Springer, pp. 247–253, 2014.
ista: Sazanov LA. 2014. The mechanism of coupling between electron transfer and
proton translocation in respiratory complex I. Journal of Bioenergetics and Biomembranes.
46(4), 247–253.
mla: Sazanov, Leonid A. “The Mechanism of Coupling between Electron Transfer and
Proton Translocation in Respiratory Complex I.” Journal of Bioenergetics and
Biomembranes, vol. 46, no. 4, Springer, 2014, pp. 247–53, doi:10.1007/s10863-014-9554-z.
short: L.A. Sazanov, Journal of Bioenergetics and Biomembranes 46 (2014) 247–253.
date_created: 2018-12-11T11:55:01Z
date_published: 2014-08-01T00:00:00Z
date_updated: 2021-01-12T06:54:28Z
day: '01'
doi: 10.1007/s10863-014-9554-z
extern: 1
intvolume: ' 46'
issue: '4'
month: '08'
page: 247 - 253
publication: Journal of Bioenergetics and Biomembranes
publication_status: published
publisher: Springer
publist_id: '5104'
quality_controlled: 0
status: public
title: The mechanism of coupling between electron transfer and proton translocation
in respiratory complex I
type: journal_article
volume: 46
year: '2014'
...
---
_id: '1989'
abstract:
- lang: eng
text: During animal cell division, the cleavage furrow is positioned by microtubules
that signal to the actin cortex at the cell midplane. We developed a cell-free
system to recapitulate cytokinesis signaling using cytoplasmic extract from Xenopus
eggs. Microtubules grew out as asters from artificial centrosomes and met to organize
antiparallel overlap zones. These zones blocked the interpenetration of neighboring
asters and recruited cytokinesis midzone proteins, including the chromosomal passenger
complex (CPC) and centralspindlin. The CPC was transported to overlap zones, which
required two motor proteins, Kif4A and a Kif20A paralog. Using supported lipid
bilayers to mimic the plasma membrane, we observed the recruitment of cleavage
furrow markers, including an active RhoA reporter, at microtubule overlaps. This
system opens further approaches to understanding the biophysics of cytokinesis
signaling.
acknowledgement: 'This work was supported by NIH grant GM39565 (T.J.M.); MBL fellowships
from the Evans Foundation, MBL Associates, and the Colwin Fund (T.J.M. and C.M.F.);
HFSP fellowship LT000466/2012-L (M.L.); and NIH grant GM103785 (M.W.). '
author:
- first_name: Phuong
full_name: Nguyen, Phuong A
last_name: Nguyen
- first_name: Aaron
full_name: Groen, Aaron C
last_name: Groen
- first_name: Martin
full_name: Martin Loose
id: 462D4284-F248-11E8-B48F-1D18A9856A87
last_name: Loose
orcid: 0000-0001-7309-9724
- first_name: Keisuke
full_name: 'Ishihara, Keisuke '
last_name: Ishihara
- first_name: Martin
full_name: 'Wühr, Martin '
last_name: Wühr
- first_name: Christine
full_name: Field, Christine M
last_name: Field
- first_name: Timothy
full_name: Mitchison, Timothy J
last_name: Mitchison
citation:
ama: Nguyen P, Groen A, Loose M, et al. Spatial organization of cytokinesis signaling
reconstituted in a cell-free system. Science. 2014;346(6206):244-247. doi:10.1126/science.1256773
apa: Nguyen, P., Groen, A., Loose, M., Ishihara, K., Wühr, M., Field, C., &
Mitchison, T. (2014). Spatial organization of cytokinesis signaling reconstituted
in a cell-free system. Science. American Association for the Advancement
of Science. https://doi.org/10.1126/science.1256773
chicago: Nguyen, Phuong, Aaron Groen, Martin Loose, Keisuke Ishihara, Martin Wühr,
Christine Field, and Timothy Mitchison. “Spatial Organization of Cytokinesis Signaling
Reconstituted in a Cell-Free System.” Science. American Association for
the Advancement of Science, 2014. https://doi.org/10.1126/science.1256773.
ieee: P. Nguyen et al., “Spatial organization of cytokinesis signaling reconstituted
in a cell-free system,” Science, vol. 346, no. 6206. American Association
for the Advancement of Science, pp. 244–247, 2014.
ista: Nguyen P, Groen A, Loose M, Ishihara K, Wühr M, Field C, Mitchison T. 2014.
Spatial organization of cytokinesis signaling reconstituted in a cell-free system.
Science. 346(6206), 244–247.
mla: Nguyen, Phuong, et al. “Spatial Organization of Cytokinesis Signaling Reconstituted
in a Cell-Free System.” Science, vol. 346, no. 6206, American Association
for the Advancement of Science, 2014, pp. 244–47, doi:10.1126/science.1256773.
short: P. Nguyen, A. Groen, M. Loose, K. Ishihara, M. Wühr, C. Field, T. Mitchison,
Science 346 (2014) 244–247.
date_created: 2018-12-11T11:55:04Z
date_published: 2014-10-10T00:00:00Z
date_updated: 2021-01-12T06:54:32Z
day: '10'
doi: 10.1126/science.1256773
extern: 1
intvolume: ' 346'
issue: '6206'
month: '10'
page: 244 - 247
publication: Science
publication_status: published
publisher: American Association for the Advancement of Science
publist_id: '5093'
quality_controlled: 0
status: public
title: Spatial organization of cytokinesis signaling reconstituted in a cell-free
system
type: journal_article
volume: 346
year: '2014'
...
---
_id: '1990'
abstract:
- lang: eng
text: 'Bacterial cytokinesis is commonly initiated by the Z-ring, a cytoskeletal
structure that assembles at the site of division. Its primary component is FtsZ,
a tubulin superfamily GTPase, which is recruited to the membrane by the actin-related
protein FtsA. Both proteins are required for the formation of the Z-ring, but
if and how they influence each other''s assembly dynamics is not known. Here,
we reconstituted FtsA-dependent recruitment of FtsZ polymers to supported membranes,
where both proteins self-organize into complex patterns, such as fast-moving filament
bundles and chirally rotating rings. Using fluorescence microscopy and biochemical
perturbations, we found that these large-scale rearrangements of FtsZ emerge from
its polymerization dynamics and a dual, antagonistic role of FtsA: recruitment
of FtsZ filaments to the membrane and negative regulation of FtsZ organization.
Our findings provide a model for the initial steps of bacterial cell division
and illustrate how dynamic polymers can self-organize into large-scale structures.'
acknowledgement: M.L. is supported by fellowships from EMBO (ALTF 394-2011) and HFSP
(LT000466/2012). Cytoskeleton dynamics research in the T.J.M. group is supported
by NIH-GM39565.
author:
- first_name: Martin
full_name: Martin Loose
id: 462D4284-F248-11E8-B48F-1D18A9856A87
last_name: Loose
orcid: 0000-0001-7309-9724
- first_name: Timothy
full_name: Mitchison, Timothy J
last_name: Mitchison
citation:
ama: Loose M, Mitchison T. The bacterial cell division proteins ftsA and ftsZ self-organize
into dynamic cytoskeletal patterns. Nature Cell Biology. 2014;16(1):38-46.
doi:10.1038/ncb2885
apa: Loose, M., & Mitchison, T. (2014). The bacterial cell division proteins
ftsA and ftsZ self-organize into dynamic cytoskeletal patterns. Nature Cell
Biology. Nature Publishing Group. https://doi.org/10.1038/ncb2885
chicago: Loose, Martin, and Timothy Mitchison. “The Bacterial Cell Division Proteins
FtsA and FtsZ Self-Organize into Dynamic Cytoskeletal Patterns.” Nature Cell
Biology. Nature Publishing Group, 2014. https://doi.org/10.1038/ncb2885.
ieee: M. Loose and T. Mitchison, “The bacterial cell division proteins ftsA and
ftsZ self-organize into dynamic cytoskeletal patterns,” Nature Cell Biology,
vol. 16, no. 1. Nature Publishing Group, pp. 38–46, 2014.
ista: Loose M, Mitchison T. 2014. The bacterial cell division proteins ftsA and
ftsZ self-organize into dynamic cytoskeletal patterns. Nature Cell Biology. 16(1),
38–46.
mla: Loose, Martin, and Timothy Mitchison. “The Bacterial Cell Division Proteins
FtsA and FtsZ Self-Organize into Dynamic Cytoskeletal Patterns.” Nature Cell
Biology, vol. 16, no. 1, Nature Publishing Group, 2014, pp. 38–46, doi:10.1038/ncb2885.
short: M. Loose, T. Mitchison, Nature Cell Biology 16 (2014) 38–46.
date_created: 2018-12-11T11:55:05Z
date_published: 2014-01-01T00:00:00Z
date_updated: 2021-01-12T06:54:33Z
day: '01'
doi: 10.1038/ncb2885
extern: 1
intvolume: ' 16'
issue: '1'
month: '01'
page: 38 - 46
publication: Nature Cell Biology
publication_status: published
publisher: Nature Publishing Group
publist_id: '5094'
quality_controlled: 0
status: public
title: The bacterial cell division proteins ftsA and ftsZ self-organize into dynamic
cytoskeletal patterns
type: journal_article
volume: 16
year: '2014'
...
---
_id: '1996'
abstract:
- lang: eng
text: Auxin polar transport, local maxima, and gradients have become an importantmodel
system for studying self-organization. Auxin distribution is regulated by auxin-dependent
positive feedback loops that are not well-understood at the molecular level. Previously,
we showed the involvement of the RHO of Plants (ROP) effector INTERACTOR of CONSTITUTIVELY
active ROP 1 (ICR1) in regulation of auxin transport and that ICR1 levels are
posttranscriptionally repressed at the site of maximum auxin accumulation at the
root tip. Here, we show that bimodal regulation of ICR1 levels by auxin is essential
for regulating formation of auxin local maxima and gradients. ICR1 levels increase
concomitant with increase in auxin response in lateral root primordia, cotyledon
tips, and provascular tissues. However, in the embryo hypophysis and root meristem,
when auxin exceeds critical levels, ICR1 is rapidly destabilized by an SCF(TIR1/AFB)
[SKP, Cullin, F-box (transport inhibitor response 1/auxin signaling F-box protein)]-dependent
auxin signaling mechanism. Furthermore, ectopic expression of ICR1 in the embryo
hypophysis resulted in reduction of auxin accumulation and concomitant root growth
arrest. ICR1 disappeared during root regeneration and lateral root initiation
concomitantly with the formation of a local auxin maximum in response to external
auxin treatments and transiently after gravitropic stimulation. Destabilization
of ICR1 was impaired after inhibition of auxin transport and signaling, proteasome
function, and protein synthesis. A mathematical model based on these findings
shows that an in vivo-like auxin distribution, rootward auxin flux, and shootward
reflux can be simulated without assuming preexisting tissue polarity. Our experimental
results and mathematical modeling indicate that regulation of auxin distribution
is tightly associated with auxin-dependent ICR1 levels.
author:
- first_name: Ora
full_name: Hazak, Ora
last_name: Hazak
- first_name: Uri
full_name: Obolski, Uri
last_name: Obolski
- first_name: Tomas
full_name: Prat, Tomas
id: 3DA3BFEE-F248-11E8-B48F-1D18A9856A87
last_name: Prat
- first_name: Jiří
full_name: Friml, Jiří
id: 4159519E-F248-11E8-B48F-1D18A9856A87
last_name: Friml
orcid: 0000-0002-8302-7596
- first_name: Lilach
full_name: Hadany, Lilach
last_name: Hadany
- first_name: Shaul
full_name: Yalovsky, Shaul
last_name: Yalovsky
citation:
ama: Hazak O, Obolski U, Prat T, Friml J, Hadany L, Yalovsky S. Bimodal regulation
of ICR1 levels generates self-organizing auxin distribution. PNAS. 2014;111(50):E5471-E5479.
doi:10.1073/pnas.1413918111
apa: Hazak, O., Obolski, U., Prat, T., Friml, J., Hadany, L., & Yalovsky, S.
(2014). Bimodal regulation of ICR1 levels generates self-organizing auxin distribution.
PNAS. National Academy of Sciences. https://doi.org/10.1073/pnas.1413918111
chicago: Hazak, Ora, Uri Obolski, Tomas Prat, Jiří Friml, Lilach Hadany, and Shaul
Yalovsky. “Bimodal Regulation of ICR1 Levels Generates Self-Organizing Auxin Distribution.”
PNAS. National Academy of Sciences, 2014. https://doi.org/10.1073/pnas.1413918111.
ieee: O. Hazak, U. Obolski, T. Prat, J. Friml, L. Hadany, and S. Yalovsky, “Bimodal
regulation of ICR1 levels generates self-organizing auxin distribution,” PNAS,
vol. 111, no. 50. National Academy of Sciences, pp. E5471–E5479, 2014.
ista: Hazak O, Obolski U, Prat T, Friml J, Hadany L, Yalovsky S. 2014. Bimodal regulation
of ICR1 levels generates self-organizing auxin distribution. PNAS. 111(50), E5471–E5479.
mla: Hazak, Ora, et al. “Bimodal Regulation of ICR1 Levels Generates Self-Organizing
Auxin Distribution.” PNAS, vol. 111, no. 50, National Academy of Sciences,
2014, pp. E5471–79, doi:10.1073/pnas.1413918111.
short: O. Hazak, U. Obolski, T. Prat, J. Friml, L. Hadany, S. Yalovsky, PNAS 111
(2014) E5471–E5479.
date_created: 2018-12-11T11:55:07Z
date_published: 2014-12-16T00:00:00Z
date_updated: 2021-01-12T06:54:35Z
day: '16'
department:
- _id: JiFr
doi: 10.1073/pnas.1413918111
intvolume: ' 111'
issue: '50'
language:
- iso: eng
main_file_link:
- open_access: '1'
url: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4273421/
month: '12'
oa: 1
oa_version: Submitted Version
page: E5471 - E5479
publication: PNAS
publication_status: published
publisher: National Academy of Sciences
publist_id: '5083'
quality_controlled: '1'
scopus_import: 1
status: public
title: Bimodal regulation of ICR1 levels generates self-organizing auxin distribution
type: journal_article
user_id: 4435EBFC-F248-11E8-B48F-1D18A9856A87
volume: 111
year: '2014'
...
---
_id: '1994'
abstract:
- lang: eng
text: The emergence and radiation of multicellular land plants was driven by crucial
innovations to their body plans [1]. The directional transport of the phytohormone
auxin represents a key, plant-specific mechanism for polarization and patterning
in complex seed plants [2-5]. Here, we show that already in the early diverging
land plant lineage, as exemplified by the moss Physcomitrella patens, auxin transport
by PIN transporters is operational and diversified into ER-localized and plasma
membrane-localized PIN proteins. Gain-of-function and loss-of-function analyses
revealed that PIN-dependent intercellular auxin transport in Physcomitrella mediates
crucial developmental transitions in tip-growing filaments and waves of polarization
and differentiation in leaf-like structures. Plasma membrane PIN proteins localize
in a polar manner to the tips of moss filaments, revealing an unexpected relation
between polarization mechanisms in moss tip-growing cells and multicellular tissues
of seed plants. Our results trace the origins of polarization and auxin-mediated
patterning mechanisms and highlight the crucial role of polarized auxin transport
during the evolution of multicellular land plants.
author:
- first_name: Tom
full_name: Viaene, Tom
last_name: Viaene
- first_name: Katarina
full_name: Landberg, Katarina
last_name: Landberg
- first_name: Mattias
full_name: Thelander, Mattias
last_name: Thelander
- first_name: Eva
full_name: Medvecka, Eva
last_name: Medvecka
- first_name: Eric
full_name: Pederson, Eric
last_name: Pederson
- first_name: Elena
full_name: Feraru, Elena
last_name: Feraru
- first_name: Endymion
full_name: Cooper, Endymion
last_name: Cooper
- first_name: Mansour
full_name: Karimi, Mansour
last_name: Karimi
- first_name: Charles
full_name: Delwiche, Charles
last_name: Delwiche
- first_name: Karin
full_name: Ljung, Karin
last_name: Ljung
- first_name: Markus
full_name: Geisler, Markus
last_name: Geisler
- first_name: Eva
full_name: Sundberg, Eva
last_name: Sundberg
- first_name: Jirí
full_name: Friml, Jirí
id: 4159519E-F248-11E8-B48F-1D18A9856A87
last_name: Friml
orcid: 0000-0002-8302-7596
citation:
ama: Viaene T, Landberg K, Thelander M, et al. Directional auxin transport mechanisms
in early diverging land plants. Current Biology. 2014;24(23):2786-2791.
doi:10.1016/j.cub.2014.09.056
apa: Viaene, T., Landberg, K., Thelander, M., Medvecka, E., Pederson, E., Feraru,
E., … Friml, J. (2014). Directional auxin transport mechanisms in early diverging
land plants. Current Biology. Cell Press. https://doi.org/10.1016/j.cub.2014.09.056
chicago: Viaene, Tom, Katarina Landberg, Mattias Thelander, Eva Medvecka, Eric Pederson,
Elena Feraru, Endymion Cooper, et al. “Directional Auxin Transport Mechanisms
in Early Diverging Land Plants.” Current Biology. Cell Press, 2014. https://doi.org/10.1016/j.cub.2014.09.056.
ieee: T. Viaene et al., “Directional auxin transport mechanisms in early
diverging land plants,” Current Biology, vol. 24, no. 23. Cell Press, pp.
2786–2791, 2014.
ista: Viaene T, Landberg K, Thelander M, Medvecka E, Pederson E, Feraru E, Cooper
E, Karimi M, Delwiche C, Ljung K, Geisler M, Sundberg E, Friml J. 2014. Directional
auxin transport mechanisms in early diverging land plants. Current Biology. 24(23),
2786–2791.
mla: Viaene, Tom, et al. “Directional Auxin Transport Mechanisms in Early Diverging
Land Plants.” Current Biology, vol. 24, no. 23, Cell Press, 2014, pp. 2786–91,
doi:10.1016/j.cub.2014.09.056.
short: T. Viaene, K. Landberg, M. Thelander, E. Medvecka, E. Pederson, E. Feraru,
E. Cooper, M. Karimi, C. Delwiche, K. Ljung, M. Geisler, E. Sundberg, J. Friml,
Current Biology 24 (2014) 2786–2791.
date_created: 2018-12-11T11:55:06Z
date_published: 2014-12-01T00:00:00Z
date_updated: 2021-01-12T06:54:34Z
day: '01'
department:
- _id: JiFr
doi: 10.1016/j.cub.2014.09.056
ec_funded: 1
intvolume: ' 24'
issue: '23'
language:
- iso: eng
month: '12'
oa_version: None
page: 2786 - 2791
project:
- _id: 25716A02-B435-11E9-9278-68D0E5697425
call_identifier: FP7
grant_number: '282300'
name: Polarity and subcellular dynamics in plants
publication: Current Biology
publication_status: published
publisher: Cell Press
publist_id: '5088'
quality_controlled: '1'
scopus_import: 1
status: public
title: Directional auxin transport mechanisms in early diverging land plants
type: journal_article
user_id: 4435EBFC-F248-11E8-B48F-1D18A9856A87
volume: 24
year: '2014'
...
---
_id: '1995'
abstract:
- lang: eng
text: 'Optical transport represents a natural route towards fast communications,
and it is currently used in large scale data transfer. The progressive miniaturization
of devices for information processing calls for the microscopic tailoring of light
transport and confinement at length scales appropriate for upcoming technologies.
With this goal in mind, we present a theoretical analysis of a one-dimensional
Fabry-Perot interferometer built with two highly saturable nonlinear mirrors:
a pair of two-level systems. Our approach captures nonlinear and nonreciprocal
effects of light transport that were not reported previously. Remarkably, we show
that such an elementary device can operate as a microscopic integrated optical
rectifier.'
article_number: '243601'
author:
- first_name: Filippo
full_name: Fratini, Filippo
last_name: Fratini
- first_name: Eduardo
full_name: Mascarenhas, Eduardo
last_name: Mascarenhas
- first_name: Laleh
full_name: Safari, Laleh
id: 3C325E5E-F248-11E8-B48F-1D18A9856A87
last_name: Safari
- first_name: Jean
full_name: Poizat, Jean
last_name: Poizat
- first_name: Daniel
full_name: Valente, Daniel
last_name: Valente
- first_name: Alexia
full_name: Auffèves, Alexia
last_name: Auffèves
- first_name: Dario
full_name: Gerace, Dario
last_name: Gerace
- first_name: Marcelo
full_name: Santos, Marcelo
last_name: Santos
citation:
ama: 'Fratini F, Mascarenhas E, Safari L, et al. Fabry-Perot interferometer with
quantum mirrors: Nonlinear light transport and rectification. Physical Review
Letters. 2014;113(24). doi:10.1103/PhysRevLett.113.243601'
apa: 'Fratini, F., Mascarenhas, E., Safari, L., Poizat, J., Valente, D., Auffèves,
A., … Santos, M. (2014). Fabry-Perot interferometer with quantum mirrors: Nonlinear
light transport and rectification. Physical Review Letters. American Physical
Society. https://doi.org/10.1103/PhysRevLett.113.243601'
chicago: 'Fratini, Filippo, Eduardo Mascarenhas, Laleh Safari, Jean Poizat, Daniel
Valente, Alexia Auffèves, Dario Gerace, and Marcelo Santos. “Fabry-Perot Interferometer
with Quantum Mirrors: Nonlinear Light Transport and Rectification.” Physical
Review Letters. American Physical Society, 2014. https://doi.org/10.1103/PhysRevLett.113.243601.'
ieee: 'F. Fratini et al., “Fabry-Perot interferometer with quantum mirrors:
Nonlinear light transport and rectification,” Physical Review Letters,
vol. 113, no. 24. American Physical Society, 2014.'
ista: 'Fratini F, Mascarenhas E, Safari L, Poizat J, Valente D, Auffèves A, Gerace
D, Santos M. 2014. Fabry-Perot interferometer with quantum mirrors: Nonlinear
light transport and rectification. Physical Review Letters. 113(24), 243601.'
mla: 'Fratini, Filippo, et al. “Fabry-Perot Interferometer with Quantum Mirrors:
Nonlinear Light Transport and Rectification.” Physical Review Letters,
vol. 113, no. 24, 243601, American Physical Society, 2014, doi:10.1103/PhysRevLett.113.243601.'
short: F. Fratini, E. Mascarenhas, L. Safari, J. Poizat, D. Valente, A. Auffèves,
D. Gerace, M. Santos, Physical Review Letters 113 (2014).
date_created: 2018-12-11T11:55:06Z
date_published: 2014-12-08T00:00:00Z
date_updated: 2021-01-12T06:54:34Z
day: '08'
department:
- _id: MiLe
doi: 10.1103/PhysRevLett.113.243601
ec_funded: 1
intvolume: ' 113'
issue: '24'
language:
- iso: eng
main_file_link:
- open_access: '1'
url: http://arxiv.org/abs/1410.5972
month: '12'
oa: 1
oa_version: Submitted Version
project:
- _id: 25681D80-B435-11E9-9278-68D0E5697425
call_identifier: FP7
grant_number: '291734'
name: International IST Postdoc Fellowship Programme
publication: Physical Review Letters
publication_status: published
publisher: American Physical Society
publist_id: '5085'
quality_controlled: '1'
scopus_import: 1
status: public
title: 'Fabry-Perot interferometer with quantum mirrors: Nonlinear light transport
and rectification'
type: journal_article
user_id: 4435EBFC-F248-11E8-B48F-1D18A9856A87
volume: 113
year: '2014'
...
---
_id: '1998'
abstract:
- lang: eng
text: Immune systems are able to protect the body against secondary infection with
the same parasite. In insect colonies, this protection is not restricted to the
level of the individual organism, but also occurs at the societal level. Here,
we review recent evidence for and insights into the mechanisms underlying individual
and social immunisation in insects. We disentangle general immune-protective effects
from specific immune memory (priming), and examine immunisation in the context
of the lifetime of an individual and that of a colony, and of transgenerational
immunisation that benefits offspring. When appropriate, we discuss parallels with
disease defence strategies in human societies. We propose that recurrent parasitic
threats have shaped the evolution of both the individual immune systems and colony-level
social immunity in insects.
acknowledgement: "This work was funded by an ERC Starting Grant by the European Research
Council (to S.C.) and the ISTFELLOW program (Co-fund Marie Curie Actions of the
European Commission; to L.M.).\r\nWe thank Christopher D. Pull, Sophie A.O. Armitage,
Hinrich Schulenburg, Line V. Ugelvig, Matthias Konrad, Matthias Fürst, Miriam Stock,
Barbara Casillas-Perez and three anonymous referees for comments on the manuscript. "
author:
- first_name: Leila
full_name: El Masri, Leila
id: 349A6E66-F248-11E8-B48F-1D18A9856A87
last_name: El Masri
- first_name: Sylvia
full_name: Cremer, Sylvia
id: 2F64EC8C-F248-11E8-B48F-1D18A9856A87
last_name: Cremer
orcid: 0000-0002-2193-3868
citation:
ama: El Masri L, Cremer S. Individual and social immunisation in insects. Trends
in Immunology. 2014;35(10):471-482. doi:10.1016/j.it.2014.08.005
apa: El Masri, L., & Cremer, S. (2014). Individual and social immunisation in
insects. Trends in Immunology. Elsevier. https://doi.org/10.1016/j.it.2014.08.005
chicago: El Masri, Leila, and Sylvia Cremer. “Individual and Social Immunisation
in Insects.” Trends in Immunology. Elsevier, 2014. https://doi.org/10.1016/j.it.2014.08.005.
ieee: L. El Masri and S. Cremer, “Individual and social immunisation in insects,”
Trends in Immunology, vol. 35, no. 10. Elsevier, pp. 471–482, 2014.
ista: El Masri L, Cremer S. 2014. Individual and social immunisation in insects.
Trends in Immunology. 35(10), 471–482.
mla: El Masri, Leila, and Sylvia Cremer. “Individual and Social Immunisation in
Insects.” Trends in Immunology, vol. 35, no. 10, Elsevier, 2014, pp. 471–82,
doi:10.1016/j.it.2014.08.005.
short: L. El Masri, S. Cremer, Trends in Immunology 35 (2014) 471–482.
date_created: 2018-12-11T11:55:07Z
date_published: 2014-10-01T00:00:00Z
date_updated: 2021-01-12T06:54:35Z
day: '01'
department:
- _id: SyCr
doi: 10.1016/j.it.2014.08.005
intvolume: ' 35'
issue: '10'
language:
- iso: eng
month: '10'
oa_version: None
page: 471 - 482
publication: Trends in Immunology
publication_status: published
publisher: Elsevier
publist_id: '5081'
quality_controlled: '1'
scopus_import: 1
status: public
title: Individual and social immunisation in insects
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 35
year: '2014'
...
---
_id: '2002'
abstract:
- lang: eng
text: Oriens-lacunosum moleculare (O-LM) interneurons in the CA1 region of the hippocampus
play a key role in feedback inhibition and in the control of network activity.
However, how these cells are efficiently activated in the network remains unclear.
To address this question, I performed recordings from CA1 pyramidal neuron axons,
the presynaptic fibers that provide feedback innervation of these interneurons.
Two forms of axonal action potential (AP) modulation were identified. First, repetitive
stimulation resulted in activity-dependent AP broadening. Broadening showed fast
onset, with marked changes in AP shape following a single AP. Second, tonic depolarization
in CA1 pyramidal neuron somata induced AP broadening in the axon, and depolarization-induced
broadening summated with activity-dependent broadening. Outsideout patch recordings
from CA1 pyramidal neuron axons revealed a high density of a-dendrotoxin (α-DTX)-sensitive,
inactivating K+ channels, suggesting that K+ channel inactivation mechanistically
contributes to AP broadening. To examine the functional consequences of axonal
AP modulation for synaptic transmission, I performed paired recordings between
synaptically connected CA1 pyramidal neurons and O-LM interneurons. CA1 pyramidal
neuron-O-LM interneuron excitatory postsynaptic currents (EPSCs) showed facilitation
during both repetitive stimulation and tonic depolarization of the presynaptic
neuron. Both effects were mimicked and occluded by α-DTX, suggesting that they
were mediated by K+ channel inactivation. Therefore, axonal AP modulation can
greatly facilitate the activation of O-LM interneurons. In conclusion, modulation
of AP shape in CA1 pyramidal neuron axons substantially enhances the efficacy
of principal neuron-interneuron synapses, promoting the activation of O-LM interneurons
in recurrent inhibitory microcircuits.
article_number: '0113124'
author:
- first_name: Sooyun
full_name: Kim, Sooyun
id: 394AB1C8-F248-11E8-B48F-1D18A9856A87
last_name: Kim
citation:
ama: Kim S. Action potential modulation in CA1 pyramidal neuron axons facilitates
OLM interneuron activation in recurrent inhibitory microcircuits of rat hippocampus.
PLoS One. 2014;9(11). doi:10.1371/journal.pone.0113124
apa: Kim, S. (2014). Action potential modulation in CA1 pyramidal neuron axons facilitates
OLM interneuron activation in recurrent inhibitory microcircuits of rat hippocampus.
PLoS One. Public Library of Science. https://doi.org/10.1371/journal.pone.0113124
chicago: Kim, Sooyun. “Action Potential Modulation in CA1 Pyramidal Neuron Axons
Facilitates OLM Interneuron Activation in Recurrent Inhibitory Microcircuits of
Rat Hippocampus.” PLoS One. Public Library of Science, 2014. https://doi.org/10.1371/journal.pone.0113124.
ieee: S. Kim, “Action potential modulation in CA1 pyramidal neuron axons facilitates
OLM interneuron activation in recurrent inhibitory microcircuits of rat hippocampus,”
PLoS One, vol. 9, no. 11. Public Library of Science, 2014.
ista: Kim S. 2014. Action potential modulation in CA1 pyramidal neuron axons facilitates
OLM interneuron activation in recurrent inhibitory microcircuits of rat hippocampus.
PLoS One. 9(11), 0113124.
mla: Kim, Sooyun. “Action Potential Modulation in CA1 Pyramidal Neuron Axons Facilitates
OLM Interneuron Activation in Recurrent Inhibitory Microcircuits of Rat Hippocampus.”
PLoS One, vol. 9, no. 11, 0113124, Public Library of Science, 2014, doi:10.1371/journal.pone.0113124.
short: S. Kim, PLoS One 9 (2014).
date_created: 2018-12-11T11:55:09Z
date_published: 2014-11-19T00:00:00Z
date_updated: 2021-01-12T06:54:39Z
day: '19'
ddc:
- '570'
department:
- _id: PeJo
doi: 10.1371/journal.pone.0113124
ec_funded: 1
file:
- access_level: open_access
checksum: 85e4f4ea144f827272aaf376b2830564
content_type: application/pdf
creator: system
date_created: 2018-12-12T10:14:52Z
date_updated: 2020-07-14T12:45:24Z
file_id: '5107'
file_name: IST-2016-434-v1+1_journal.pone.0113124.pdf
file_size: 5179993
relation: main_file
file_date_updated: 2020-07-14T12:45:24Z
has_accepted_license: '1'
intvolume: ' 9'
issue: '11'
language:
- iso: eng
license: https://creativecommons.org/licenses/by-sa/4.0/
month: '11'
oa: 1
oa_version: Published Version
project:
- _id: 25C0F108-B435-11E9-9278-68D0E5697425
call_identifier: FP7
grant_number: '268548'
name: Nanophysiology of fast-spiking, parvalbumin-expressing GABAergic interneurons
publication: PLoS One
publication_status: published
publisher: Public Library of Science
publist_id: '5074'
pubrep_id: '434'
quality_controlled: '1'
scopus_import: 1
status: public
title: Action potential modulation in CA1 pyramidal neuron axons facilitates OLM interneuron
activation in recurrent inhibitory microcircuits of rat hippocampus
tmp:
image: /images/cc_by_sa.png
legal_code_url: https://creativecommons.org/licenses/by-sa/4.0/legalcode
name: Creative Commons Attribution-ShareAlike 4.0 International Public License (CC
BY-SA 4.0)
short: CC BY-SA (4.0)
type: journal_article
user_id: 4435EBFC-F248-11E8-B48F-1D18A9856A87
volume: 9
year: '2014'
...
---
_id: '2003'
abstract:
- lang: eng
text: Learning can be facilitated by previous knowledge when it is organized into
relational representations forming schemas. In this issue of Neuron, McKenzie
et al. (2014) demonstrate that the hippocampus rapidly forms interrelated, hierarchical
memory representations to support schema-based learning.
author:
- first_name: Joseph
full_name: O'Neill, Joseph
id: 426376DC-F248-11E8-B48F-1D18A9856A87
last_name: O'Neill
- first_name: Jozsef L
full_name: Csicsvari, Jozsef L
id: 3FA14672-F248-11E8-B48F-1D18A9856A87
last_name: Csicsvari
orcid: 0000-0002-5193-4036
citation:
ama: O’Neill J, Csicsvari JL. Learning by example in the hippocampus. Neuron.
2014;83(1):8-10. doi:10.1016/j.neuron.2014.06.013
apa: O’Neill, J., & Csicsvari, J. L. (2014). Learning by example in the hippocampus.
Neuron. Elsevier. https://doi.org/10.1016/j.neuron.2014.06.013
chicago: O’Neill, Joseph, and Jozsef L Csicsvari. “Learning by Example in the Hippocampus.”
Neuron. Elsevier, 2014. https://doi.org/10.1016/j.neuron.2014.06.013.
ieee: J. O’Neill and J. L. Csicsvari, “Learning by example in the hippocampus,”
Neuron, vol. 83, no. 1. Elsevier, pp. 8–10, 2014.
ista: O’Neill J, Csicsvari JL. 2014. Learning by example in the hippocampus. Neuron.
83(1), 8–10.
mla: O’Neill, Joseph, and Jozsef L. Csicsvari. “Learning by Example in the Hippocampus.”
Neuron, vol. 83, no. 1, Elsevier, 2014, pp. 8–10, doi:10.1016/j.neuron.2014.06.013.
short: J. O’Neill, J.L. Csicsvari, Neuron 83 (2014) 8–10.
date_created: 2018-12-11T11:55:09Z
date_published: 2014-07-02T00:00:00Z
date_updated: 2021-01-12T06:54:39Z
day: '02'
department:
- _id: JoCs
doi: 10.1016/j.neuron.2014.06.013
intvolume: ' 83'
issue: '1'
language:
- iso: eng
month: '07'
oa_version: None
page: 8 - 10
publication: Neuron
publication_status: published
publisher: Elsevier
publist_id: '5073'
quality_controlled: '1'
scopus_import: 1
status: public
title: Learning by example in the hippocampus
type: journal_article
user_id: 4435EBFC-F248-11E8-B48F-1D18A9856A87
volume: 83
year: '2014'
...
---
_id: '2011'
abstract:
- lang: eng
text: The protection of privacy of individual-level information in genome-wide association
study (GWAS) databases has been a major concern of researchers following the publication
of “an attack” on GWAS data by Homer et al. (2008). Traditional statistical methods
for confidentiality and privacy protection of statistical databases do not scale
well to deal with GWAS data, especially in terms of guarantees regarding protection
from linkage to external information. The more recent concept of differential
privacy, introduced by the cryptographic community, is an approach that provides
a rigorous definition of privacy with meaningful privacy guarantees in the presence
of arbitrary external information, although the guarantees may come at a serious
price in terms of data utility. Building on such notions, Uhler et al. (2013)
proposed new methods to release aggregate GWAS data without compromising an individual’s
privacy. We extend the methods developed in Uhler et al. (2013) for releasing
differentially-private χ2χ2-statistics by allowing for arbitrary number of cases
and controls, and for releasing differentially-private allelic test statistics.
We also provide a new interpretation by assuming the controls’ data are known,
which is a realistic assumption because some GWAS use publicly available data
as controls. We assess the performance of the proposed methods through a risk-utility
analysis on a real data set consisting of DNA samples collected by the Wellcome
Trust Case Control Consortium and compare the methods with the differentially-private
release mechanism proposed by Johnson and Shmatikov (2013).
acknowledgement: This research was partially supported by NSF Awards EMSW21-RTG and
BCS-0941518 to the Department of Statistics at Carnegie Mellon University, and by
NSF Grant BCS-0941553 to the Department of Statistics at Pennsylvania State University.
This work was also supported in part by the National Center for Research Resources,
Grant UL1 RR033184, and is now at the National Center for Advancing Translational
Sciences, Grant UL1 TR000127 to Pennsylvania State University. The content is solely
the responsibility of the authors and does not necessarily represent the official
views of the NSF and NIH.
author:
- first_name: Fei
full_name: Yu, Fei
last_name: Yu
- first_name: Stephen
full_name: Fienberg, Stephen
last_name: Fienberg
- first_name: Alexandra
full_name: Slaković, Alexandra
last_name: Slaković
- first_name: Caroline
full_name: Uhler, Caroline
id: 49ADD78E-F248-11E8-B48F-1D18A9856A87
last_name: Uhler
orcid: 0000-0002-7008-0216
citation:
ama: Yu F, Fienberg S, Slaković A, Uhler C. Scalable privacy-preserving data sharing
methodology for genome-wide association studies. Journal of Biomedical Informatics.
2014;50:133-141. doi:10.1016/j.jbi.2014.01.008
apa: Yu, F., Fienberg, S., Slaković, A., & Uhler, C. (2014). Scalable privacy-preserving
data sharing methodology for genome-wide association studies. Journal of Biomedical
Informatics. Elsevier. https://doi.org/10.1016/j.jbi.2014.01.008
chicago: Yu, Fei, Stephen Fienberg, Alexandra Slaković, and Caroline Uhler. “Scalable
Privacy-Preserving Data Sharing Methodology for Genome-Wide Association Studies.”
Journal of Biomedical Informatics. Elsevier, 2014. https://doi.org/10.1016/j.jbi.2014.01.008.
ieee: F. Yu, S. Fienberg, A. Slaković, and C. Uhler, “Scalable privacy-preserving
data sharing methodology for genome-wide association studies,” Journal of Biomedical
Informatics, vol. 50. Elsevier, pp. 133–141, 2014.
ista: Yu F, Fienberg S, Slaković A, Uhler C. 2014. Scalable privacy-preserving data
sharing methodology for genome-wide association studies. Journal of Biomedical
Informatics. 50, 133–141.
mla: Yu, Fei, et al. “Scalable Privacy-Preserving Data Sharing Methodology for Genome-Wide
Association Studies.” Journal of Biomedical Informatics, vol. 50, Elsevier,
2014, pp. 133–41, doi:10.1016/j.jbi.2014.01.008.
short: F. Yu, S. Fienberg, A. Slaković, C. Uhler, Journal of Biomedical Informatics
50 (2014) 133–141.
date_created: 2018-12-11T11:55:12Z
date_published: 2014-08-01T00:00:00Z
date_updated: 2021-01-12T06:54:42Z
day: '01'
department:
- _id: CaUh
doi: 10.1016/j.jbi.2014.01.008
intvolume: ' 50'
language:
- iso: eng
main_file_link:
- open_access: '1'
url: http://arxiv.org/abs/1401.5193
month: '08'
oa: 1
oa_version: Submitted Version
page: 133 - 141
publication: Journal of Biomedical Informatics
publication_status: published
publisher: Elsevier
publist_id: '5065'
quality_controlled: '1'
scopus_import: 1
status: public
title: Scalable privacy-preserving data sharing methodology for genome-wide association
studies
type: journal_article
user_id: 4435EBFC-F248-11E8-B48F-1D18A9856A87
volume: 50
year: '2014'
...
---
_id: '2005'
abstract:
- lang: eng
text: By eliciting a natural exploratory behavior in rats, head scanning, a study
reveals that hippocampal place cells form new, stable firing fields in those locations
where the behavior has just occurred.
author:
- first_name: David
full_name: Dupret, David
last_name: Dupret
- first_name: Jozsef L
full_name: Csicsvari, Jozsef L
id: 3FA14672-F248-11E8-B48F-1D18A9856A87
last_name: Csicsvari
orcid: 0000-0002-5193-4036
citation:
ama: Dupret D, Csicsvari JL. Turning heads to remember places. Nature Neuroscience.
2014;17(5):643-644. doi:10.1038/nn.3700
apa: Dupret, D., & Csicsvari, J. L. (2014). Turning heads to remember places.
Nature Neuroscience. Nature Publishing Group. https://doi.org/10.1038/nn.3700
chicago: Dupret, David, and Jozsef L Csicsvari. “Turning Heads to Remember Places.”
Nature Neuroscience. Nature Publishing Group, 2014. https://doi.org/10.1038/nn.3700.
ieee: D. Dupret and J. L. Csicsvari, “Turning heads to remember places,” Nature
Neuroscience, vol. 17, no. 5. Nature Publishing Group, pp. 643–644, 2014.
ista: Dupret D, Csicsvari JL. 2014. Turning heads to remember places. Nature Neuroscience.
17(5), 643–644.
mla: Dupret, David, and Jozsef L. Csicsvari. “Turning Heads to Remember Places.”
Nature Neuroscience, vol. 17, no. 5, Nature Publishing Group, 2014, pp.
643–44, doi:10.1038/nn.3700.
short: D. Dupret, J.L. Csicsvari, Nature Neuroscience 17 (2014) 643–644.
date_created: 2018-12-11T11:55:09Z
date_published: 2014-04-25T00:00:00Z
date_updated: 2021-01-12T06:54:40Z
day: '25'
department:
- _id: JoCs
doi: 10.1038/nn.3700
intvolume: ' 17'
issue: '5'
language:
- iso: eng
month: '04'
oa_version: None
page: 643 - 644
publication: Nature Neuroscience
publication_status: published
publisher: Nature Publishing Group
publist_id: '5071'
quality_controlled: '1'
scopus_import: 1
status: public
title: Turning heads to remember places
type: journal_article
user_id: 4435EBFC-F248-11E8-B48F-1D18A9856A87
volume: 17
year: '2014'
...
---
_id: '2007'
abstract:
- lang: eng
text: Maximum likelihood estimation under relational models, with or without the
overall effect. For more information see the reference manual
article_processing_charge: No
author:
- first_name: Anna
full_name: Klimova, Anna
id: 31934120-F248-11E8-B48F-1D18A9856A87
last_name: Klimova
- first_name: Tamás
full_name: Rudas, Tamás
last_name: Rudas
citation:
ama: 'Klimova A, Rudas T. gIPFrm: Generalized iterative proportional fitting for
relational models. 2014.'
apa: 'Klimova, A., & Rudas, T. (2014). gIPFrm: Generalized iterative proportional
fitting for relational models. The Comprehensive R Archive Network.'
chicago: 'Klimova, Anna, and Tamás Rudas. “GIPFrm: Generalized Iterative Proportional
Fitting for Relational Models.” The Comprehensive R Archive Network, 2014.'
ieee: 'A. Klimova and T. Rudas, “gIPFrm: Generalized iterative proportional fitting
for relational models.” The Comprehensive R Archive Network, 2014.'
ista: 'Klimova A, Rudas T. 2014. gIPFrm: Generalized iterative proportional fitting
for relational models, The Comprehensive R Archive Network.'
mla: 'Klimova, Anna, and Tamás Rudas. GIPFrm: Generalized Iterative Proportional
Fitting for Relational Models. The Comprehensive R Archive Network, 2014.'
short: A. Klimova, T. Rudas, (2014).
date_created: 2018-12-11T11:55:10Z
date_published: 2014-03-20T00:00:00Z
date_updated: 2022-08-26T08:12:12Z
day: '20'
department:
- _id: CaUh
main_file_link:
- open_access: '1'
url: 'https://CRAN.R-project.org/package=gIPFrm '
month: '03'
oa: 1
oa_version: Published Version
publisher: The Comprehensive R Archive Network
publist_id: '5069'
status: public
title: 'gIPFrm: Generalized iterative proportional fitting for relational models'
type: research_data_reference
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
year: '2014'
...
---
_id: '2018'
abstract:
- lang: eng
text: Synaptic cell adhesion molecules are increasingly gaining attention for conferring
specific properties to individual synapses. Netrin-G1 and netrin-G2 are trans-synaptic
adhesion molecules that distribute on distinct axons, and their presence restricts
the expression of their cognate receptors, NGL1 and NGL2, respectively, to specific
subdendritic segments of target neurons. However, the neural circuits and functional
roles of netrin-G isoform complexes remain unclear. Here, we use netrin-G-KO and
NGL-KO mice to reveal that netrin-G1/NGL1 and netrin-G2/NGL2 interactions specify
excitatory synapses in independent hippocampal pathways. In the hippocampal CA1
area, netrin-G1/NGL1 and netrin-G2/NGL2 were expressed in the temporoammonic and
Schaffer collateral pathways, respectively. The lack of presynaptic netrin-Gs
led to the dispersion of NGLs from postsynaptic membranes. In accord, netrin-G
mutant synapses displayed opposing phenotypes in long-term and short-term plasticity
through discrete biochemical pathways. The plasticity phenotypes in netrin-G-KOs
were phenocopied in NGL-KOs, with a corresponding loss of netrin-Gs from presynaptic
membranes. Our findings show that netrin-G/NGL interactions differentially control
synaptic plasticity in distinct circuits via retrograde signaling mechanisms and
explain how synaptic inputs are diversified to control neuronal activity.
acknowledgement: This work was supported by “Funding Program for World-Leading Innovative
R&D on Science and Technology (FIRST Program)” initiated by the Council for Science
and Technology Policy.
article_processing_charge: No
article_type: original
author:
- first_name: Hiroshi
full_name: Matsukawa, Hiroshi
last_name: Matsukawa
- first_name: Sachiko
full_name: Akiyoshi Nishimura, Sachiko
last_name: Akiyoshi Nishimura
- first_name: Qi
full_name: Zhang, Qi
last_name: Zhang
- first_name: Rafael
full_name: Luján, Rafael
last_name: Luján
- first_name: Kazuhiko
full_name: Yamaguchi, Kazuhiko
last_name: Yamaguchi
- first_name: Hiromichi
full_name: Goto, Hiromichi
last_name: Goto
- first_name: Kunio
full_name: Yaguchi, Kunio
last_name: Yaguchi
- first_name: Tsutomu
full_name: Hashikawa, Tsutomu
last_name: Hashikawa
- first_name: Chie
full_name: Sano, Chie
last_name: Sano
- first_name: Ryuichi
full_name: Shigemoto, Ryuichi
id: 499F3ABC-F248-11E8-B48F-1D18A9856A87
last_name: Shigemoto
orcid: 0000-0001-8761-9444
- first_name: Toshiaki
full_name: Nakashiba, Toshiaki
last_name: Nakashiba
- first_name: Shigeyoshi
full_name: Itohara, Shigeyoshi
last_name: Itohara
citation:
ama: Matsukawa H, Akiyoshi Nishimura S, Zhang Q, et al. Netrin-G/NGL complexes encode
functional synaptic diversification. Journal of Neuroscience. 2014;34(47):15779-15792.
doi:10.1523/JNEUROSCI.1141-14.2014
apa: Matsukawa, H., Akiyoshi Nishimura, S., Zhang, Q., Luján, R., Yamaguchi, K.,
Goto, H., … Itohara, S. (2014). Netrin-G/NGL complexes encode functional synaptic
diversification. Journal of Neuroscience. Society for Neuroscience. https://doi.org/10.1523/JNEUROSCI.1141-14.2014
chicago: Matsukawa, Hiroshi, Sachiko Akiyoshi Nishimura, Qi Zhang, Rafael Luján,
Kazuhiko Yamaguchi, Hiromichi Goto, Kunio Yaguchi, et al. “Netrin-G/NGL Complexes
Encode Functional Synaptic Diversification.” Journal of Neuroscience. Society
for Neuroscience, 2014. https://doi.org/10.1523/JNEUROSCI.1141-14.2014.
ieee: H. Matsukawa et al., “Netrin-G/NGL complexes encode functional synaptic
diversification,” Journal of Neuroscience, vol. 34, no. 47. Society for
Neuroscience, pp. 15779–15792, 2014.
ista: Matsukawa H, Akiyoshi Nishimura S, Zhang Q, Luján R, Yamaguchi K, Goto H,
Yaguchi K, Hashikawa T, Sano C, Shigemoto R, Nakashiba T, Itohara S. 2014. Netrin-G/NGL
complexes encode functional synaptic diversification. Journal of Neuroscience.
34(47), 15779–15792.
mla: Matsukawa, Hiroshi, et al. “Netrin-G/NGL Complexes Encode Functional Synaptic
Diversification.” Journal of Neuroscience, vol. 34, no. 47, Society for
Neuroscience, 2014, pp. 15779–92, doi:10.1523/JNEUROSCI.1141-14.2014.
short: H. Matsukawa, S. Akiyoshi Nishimura, Q. Zhang, R. Luján, K. Yamaguchi, H.
Goto, K. Yaguchi, T. Hashikawa, C. Sano, R. Shigemoto, T. Nakashiba, S. Itohara,
Journal of Neuroscience 34 (2014) 15779–15792.
date_created: 2018-12-11T11:55:14Z
date_published: 2014-11-19T00:00:00Z
date_updated: 2022-05-24T08:54:54Z
day: '19'
ddc:
- '570'
department:
- _id: RySh
doi: 10.1523/JNEUROSCI.1141-14.2014
external_id:
pmid:
- '25411505'
file:
- access_level: open_access
checksum: 6913e9bc26e9fc1c0441a739a4199229
content_type: application/pdf
creator: dernst
date_created: 2022-05-24T08:41:41Z
date_updated: 2022-05-24T08:41:41Z
file_id: '11410'
file_name: 2014_JournNeuroscience_Matsukawa.pdf
file_size: 3963728
relation: main_file
success: 1
file_date_updated: 2022-05-24T08:41:41Z
has_accepted_license: '1'
intvolume: ' 34'
issue: '47'
language:
- iso: eng
month: '11'
oa: 1
oa_version: Published Version
page: 15779 - 15792
pmid: 1
publication: Journal of Neuroscience
publication_identifier:
eissn:
- 1529-2401
issn:
- 0270-6474
publication_status: published
publisher: Society for Neuroscience
publist_id: '5054'
quality_controlled: '1'
scopus_import: '1'
status: public
title: Netrin-G/NGL complexes encode functional synaptic diversification
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 34
year: '2014'
...
---
_id: '2019'
abstract:
- lang: eng
text: We prove that the empirical density of states of quantum spin glasses on arbitrary
graphs converges to a normal distribution as long as the maximal degree is negligible
compared with the total number of edges. This extends the recent results of Keating
et al. (2014) that were proved for graphs with bounded chromatic number and with
symmetric coupling distribution. Furthermore, we generalise the result to arbitrary
hypergraphs. We test the optimality of our condition on the maximal degree for
p-uniform hypergraphs that correspond to p-spin glass Hamiltonians acting on n
distinguishable spin- 1/2 particles. At the critical threshold p = n1/2 we find
a sharp classical-quantum phase transition between the normal distribution and
the Wigner semicircle law. The former is characteristic to classical systems with
commuting variables, while the latter is a signature of noncommutative random
matrix theory.
author:
- first_name: László
full_name: Erdös, László
id: 4DBD5372-F248-11E8-B48F-1D18A9856A87
last_name: Erdös
orcid: 0000-0001-5366-9603
- first_name: Dominik J
full_name: Schröder, Dominik J
last_name: Schröder
citation:
ama: Erdös L, Schröder DJ. Phase transition in the density of states of quantum
spin glasses. Mathematical Physics, Analysis and Geometry. 2014;17(3-4):441-464.
doi:10.1007/s11040-014-9164-3
apa: Erdös, L., & Schröder, D. J. (2014). Phase transition in the density of
states of quantum spin glasses. Mathematical Physics, Analysis and Geometry.
Springer. https://doi.org/10.1007/s11040-014-9164-3
chicago: Erdös, László, and Dominik J Schröder. “Phase Transition in the Density
of States of Quantum Spin Glasses.” Mathematical Physics, Analysis and Geometry.
Springer, 2014. https://doi.org/10.1007/s11040-014-9164-3.
ieee: L. Erdös and D. J. Schröder, “Phase transition in the density of states of
quantum spin glasses,” Mathematical Physics, Analysis and Geometry, vol.
17, no. 3–4. Springer, pp. 441–464, 2014.
ista: Erdös L, Schröder DJ. 2014. Phase transition in the density of states of quantum
spin glasses. Mathematical Physics, Analysis and Geometry. 17(3–4), 441–464.
mla: Erdös, László, and Dominik J. Schröder. “Phase Transition in the Density of
States of Quantum Spin Glasses.” Mathematical Physics, Analysis and Geometry,
vol. 17, no. 3–4, Springer, 2014, pp. 441–64, doi:10.1007/s11040-014-9164-3.
short: L. Erdös, D.J. Schröder, Mathematical Physics, Analysis and Geometry 17 (2014)
441–464.
date_created: 2018-12-11T11:55:15Z
date_published: 2014-12-17T00:00:00Z
date_updated: 2021-01-12T06:54:45Z
day: '17'
department:
- _id: LaEr
doi: 10.1007/s11040-014-9164-3
ec_funded: 1
intvolume: ' 17'
issue: 3-4
language:
- iso: eng
main_file_link:
- open_access: '1'
url: http://arxiv.org/abs/1407.1552
month: '12'
oa: 1
oa_version: Submitted Version
page: 441 - 464
project:
- _id: 258DCDE6-B435-11E9-9278-68D0E5697425
call_identifier: FP7
grant_number: '338804'
name: Random matrices, universality and disordered quantum systems
publication: Mathematical Physics, Analysis and Geometry
publication_status: published
publisher: Springer
publist_id: '5053'
quality_controlled: '1'
scopus_import: 1
status: public
title: Phase transition in the density of states of quantum spin glasses
type: journal_article
user_id: 4435EBFC-F248-11E8-B48F-1D18A9856A87
volume: 17
year: '2014'
...
---
_id: '2013'
abstract:
- lang: eng
text: "An asymptotic theory is developed for computing volumes of regions in the
parameter space of a directed Gaussian graphical model that are obtained by bounding
partial correlations. We study these volumes using the method of real log canonical
thresholds from algebraic geometry. Our analysis involves the computation of the
singular loci of correlation hypersurfaces. Statistical applications include the
strong-faithfulness assumption for the PC algorithm and the quantification of
confounder bias in causal inference. A detailed analysis is presented for trees,
bow ties, tripartite graphs, and complete graphs.\r\n"
acknowledgement: This work was supported in part by the US National Science Foundation
(DMS-0968882) and the Defense Advanced Research Projects Agency (DARPA) Deep Learning
program (FA8650-10-C-7020).
author:
- first_name: Shaowei
full_name: Lin, Shaowei
last_name: Lin
- first_name: Caroline
full_name: Uhler, Caroline
id: 49ADD78E-F248-11E8-B48F-1D18A9856A87
last_name: Uhler
orcid: 0000-0002-7008-0216
- first_name: Bernd
full_name: Sturmfels, Bernd
last_name: Sturmfels
- first_name: Peter
full_name: Bühlmann, Peter
last_name: Bühlmann
citation:
ama: Lin S, Uhler C, Sturmfels B, Bühlmann P. Hypersurfaces and their singularities
in partial correlation testing. Foundations of Computational Mathematics.
2014;14(5):1079-1116. doi:10.1007/s10208-014-9205-0
apa: Lin, S., Uhler, C., Sturmfels, B., & Bühlmann, P. (2014). Hypersurfaces
and their singularities in partial correlation testing. Foundations of Computational
Mathematics. Springer. https://doi.org/10.1007/s10208-014-9205-0
chicago: Lin, Shaowei, Caroline Uhler, Bernd Sturmfels, and Peter Bühlmann. “Hypersurfaces
and Their Singularities in Partial Correlation Testing.” Foundations of Computational
Mathematics. Springer, 2014. https://doi.org/10.1007/s10208-014-9205-0.
ieee: S. Lin, C. Uhler, B. Sturmfels, and P. Bühlmann, “Hypersurfaces and their
singularities in partial correlation testing,” Foundations of Computational
Mathematics, vol. 14, no. 5. Springer, pp. 1079–1116, 2014.
ista: Lin S, Uhler C, Sturmfels B, Bühlmann P. 2014. Hypersurfaces and their singularities
in partial correlation testing. Foundations of Computational Mathematics. 14(5),
1079–1116.
mla: Lin, Shaowei, et al. “Hypersurfaces and Their Singularities in Partial Correlation
Testing.” Foundations of Computational Mathematics, vol. 14, no. 5, Springer,
2014, pp. 1079–116, doi:10.1007/s10208-014-9205-0.
short: S. Lin, C. Uhler, B. Sturmfels, P. Bühlmann, Foundations of Computational
Mathematics 14 (2014) 1079–1116.
date_created: 2018-12-11T11:55:12Z
date_published: 2014-10-10T00:00:00Z
date_updated: 2021-01-12T06:54:43Z
day: '10'
department:
- _id: CaUh
doi: 10.1007/s10208-014-9205-0
intvolume: ' 14'
issue: '5'
language:
- iso: eng
main_file_link:
- open_access: '1'
url: http://arxiv.org/abs/1209.0285
month: '10'
oa: 1
oa_version: Submitted Version
page: 1079 - 1116
publication: Foundations of Computational Mathematics
publication_status: published
publisher: Springer
publist_id: '5063'
quality_controlled: '1'
scopus_import: 1
status: public
title: Hypersurfaces and their singularities in partial correlation testing
type: journal_article
user_id: 4435EBFC-F248-11E8-B48F-1D18A9856A87
volume: 14
year: '2014'
...
---
_id: '2017'
abstract:
- lang: eng
text: ' Gaussian graphical models have received considerable attention during
the past four decades from the statistical and machine learning communities. In
Bayesian treatments of this model, the G-Wishart distribution serves as the conjugate
prior for inverse covariance matrices satisfying graphical constraints. While
it is straightforward to posit the unnormalized densities, the normalizing constants
of these distributions have been known only for graphs that are chordal, or decomposable.
Up until now, it was unknown whether the normalizing constant for a general graph
could be represented explicitly, and a considerable body of computational literature
emerged that attempted to avoid this apparent intractability. We close this question
by providing an explicit representation of the G-Wishart normalizing constant
for general graphs.'
acknowledgement: |-
A.L.'s research was supported by Statistics for Innovation sfi2 in Oslo.
D.R.'s research was partially supported by the U.S. National Science Foun-dation grant DMS-1309808; and by a Romberg Guest Professorship at the Heidelberg University Graduate School for Mathematical and Computational Methods in the Sciences, funded by German Universities Excellence Initiative grant GSC 220/2.
author:
- first_name: Caroline
full_name: Caroline Uhler
id: 49ADD78E-F248-11E8-B48F-1D18A9856A87
last_name: Uhler
orcid: 0000-0002-7008-0216
- first_name: Alex
full_name: Lenkoski, Alex
last_name: Lenkoski
- first_name: Donald
full_name: Richards, Donald
last_name: Richards
citation:
ama: Uhler C, Lenkoski A, Richards D. Exact formulas for the normalizing constants
of Wishart distributions for graphical models. ArXiv. 2014.
apa: Uhler, C., Lenkoski, A., & Richards, D. (2014). Exact formulas for the
normalizing constants of Wishart distributions for graphical models. ArXiv.
ArXiv.
chicago: Uhler, Caroline, Alex Lenkoski, and Donald Richards. “ Exact Formulas for
the Normalizing Constants of Wishart Distributions for Graphical Models.” ArXiv.
ArXiv, 2014.
ieee: C. Uhler, A. Lenkoski, and D. Richards, “ Exact formulas for the normalizing
constants of Wishart distributions for graphical models,” ArXiv. ArXiv,
2014.
ista: Uhler C, Lenkoski A, Richards D. 2014. Exact formulas for the normalizing
constants of Wishart distributions for graphical models. ArXiv, .
mla: Uhler, Caroline, et al. “ Exact Formulas for the Normalizing Constants of Wishart
Distributions for Graphical Models.” ArXiv, ArXiv, 2014.
short: C. Uhler, A. Lenkoski, D. Richards, ArXiv (2014).
date_created: 2018-12-11T11:55:14Z
date_published: 2014-06-18T00:00:00Z
date_updated: 2021-01-12T06:54:44Z
day: '18'
extern: 1
main_file_link:
- open_access: '1'
url: http://arxiv.org/abs/1406.4901
month: '06'
oa: 1
publication: ArXiv
publication_status: published
publisher: ArXiv
publist_id: '5058'
quality_controlled: 0
status: public
title: ' Exact formulas for the normalizing constants of Wishart distributions for
graphical models'
type: preprint
year: '2014'
...
---
_id: '2022'
abstract:
- lang: eng
text: Radial glial progenitors (RGPs) are responsible for producing nearly all neocortical
neurons. To gain insight into the patterns of RGP division and neuron production,
we quantitatively analyzed excitatory neuron genesis in the mouse neocortex using
Mosaic Analysis with Double Markers, which provides single-cell resolution of
progenitor division patterns and potential in vivo. We found that RGPs progress
through a coherent program in which their proliferative potential diminishes in
a predictable manner. Upon entry into the neurogenic phase, individual RGPs produce
∼8–9 neurons distributed in both deep and superficial layers, indicating a unitary
output in neuronal production. Removal of OTX1, a transcription factor transiently
expressed in RGPs, results in both deep- and superficial-layer neuron loss and
a reduction in neuronal unit size. Moreover, ∼1/6 of neurogenic RGPs proceed to
produce glia. These results suggest that progenitor behavior and histogenesis
in the mammalian neocortex conform to a remarkably orderly and deterministic program.
author:
- first_name: Peng
full_name: Gao, Peng
last_name: Gao
- first_name: Maria P
full_name: Postiglione, Maria P
id: 2C67902A-F248-11E8-B48F-1D18A9856A87
last_name: Postiglione
- first_name: Teresa
full_name: Krieger, Teresa
last_name: Krieger
- first_name: Luisirene
full_name: Hernandez, Luisirene
last_name: Hernandez
- first_name: Chao
full_name: Wang, Chao
last_name: Wang
- first_name: Zhi
full_name: Han, Zhi
last_name: Han
- first_name: Carmen
full_name: Streicher, Carmen
id: 36BCB99C-F248-11E8-B48F-1D18A9856A87
last_name: Streicher
- first_name: Ekaterina
full_name: Papusheva, Ekaterina
id: 41DB591E-F248-11E8-B48F-1D18A9856A87
last_name: Papusheva
- first_name: Ryan
full_name: Insolera, Ryan
last_name: Insolera
- first_name: Kritika
full_name: Chugh, Kritika
last_name: Chugh
- first_name: Oren
full_name: Kodish, Oren
last_name: Kodish
- first_name: Kun
full_name: Huang, Kun
last_name: Huang
- first_name: Benjamin
full_name: Simons, Benjamin
last_name: Simons
- first_name: Liqun
full_name: Luo, Liqun
last_name: Luo
- first_name: Simon
full_name: Hippenmeyer, Simon
id: 37B36620-F248-11E8-B48F-1D18A9856A87
last_name: Hippenmeyer
orcid: 0000-0003-2279-1061
- first_name: Song
full_name: Shi, Song
last_name: Shi
citation:
ama: Gao P, Postiglione MP, Krieger T, et al. Deterministic progenitor behavior
and unitary production of neurons in the neocortex. Cell. 2014;159(4):775-788.
doi:10.1016/j.cell.2014.10.027
apa: Gao, P., Postiglione, M. P., Krieger, T., Hernandez, L., Wang, C., Han, Z.,
… Shi, S. (2014). Deterministic progenitor behavior and unitary production of
neurons in the neocortex. Cell. Cell Press. https://doi.org/10.1016/j.cell.2014.10.027
chicago: Gao, Peng, Maria P Postiglione, Teresa Krieger, Luisirene Hernandez, Chao
Wang, Zhi Han, Carmen Streicher, et al. “Deterministic Progenitor Behavior and
Unitary Production of Neurons in the Neocortex.” Cell. Cell Press, 2014.
https://doi.org/10.1016/j.cell.2014.10.027.
ieee: P. Gao et al., “Deterministic progenitor behavior and unitary production
of neurons in the neocortex,” Cell, vol. 159, no. 4. Cell Press, pp. 775–788,
2014.
ista: Gao P, Postiglione MP, Krieger T, Hernandez L, Wang C, Han Z, Streicher C,
Papusheva E, Insolera R, Chugh K, Kodish O, Huang K, Simons B, Luo L, Hippenmeyer
S, Shi S. 2014. Deterministic progenitor behavior and unitary production of neurons
in the neocortex. Cell. 159(4), 775–788.
mla: Gao, Peng, et al. “Deterministic Progenitor Behavior and Unitary Production
of Neurons in the Neocortex.” Cell, vol. 159, no. 4, Cell Press, 2014,
pp. 775–88, doi:10.1016/j.cell.2014.10.027.
short: P. Gao, M.P. Postiglione, T. Krieger, L. Hernandez, C. Wang, Z. Han, C. Streicher,
E. Papusheva, R. Insolera, K. Chugh, O. Kodish, K. Huang, B. Simons, L. Luo, S.
Hippenmeyer, S. Shi, Cell 159 (2014) 775–788.
date_created: 2018-12-11T11:55:16Z
date_published: 2014-11-06T00:00:00Z
date_updated: 2021-01-12T06:54:47Z
day: '06'
ddc:
- '570'
department:
- _id: SiHi
- _id: Bio
doi: 10.1016/j.cell.2014.10.027
ec_funded: 1
file:
- access_level: open_access
checksum: 6c5de8329bb2ffa71cba9fda750f14ce
content_type: application/pdf
creator: system
date_created: 2018-12-12T10:08:47Z
date_updated: 2020-07-14T12:45:25Z
file_id: '4709'
file_name: IST-2016-423-v1+1_1-s2.0-S0092867414013154-main.pdf
file_size: 4435787
relation: main_file
file_date_updated: 2020-07-14T12:45:25Z
has_accepted_license: '1'
intvolume: ' 159'
issue: '4'
language:
- iso: eng
month: '11'
oa: 1
oa_version: Published Version
page: 775 - 788
project:
- _id: 25D61E48-B435-11E9-9278-68D0E5697425
call_identifier: FP7
grant_number: '618444'
name: Molecular Mechanisms of Cerebral Cortex Development
- _id: 25D7962E-B435-11E9-9278-68D0E5697425
grant_number: RGP0053/2014
name: Quantitative Structure-Function Analysis of Cerebral Cortex Assembly at Clonal
Level
publication: Cell
publication_status: published
publisher: Cell Press
publist_id: '5050'
pubrep_id: '423'
quality_controlled: '1'
scopus_import: 1
status: public
title: Deterministic progenitor behavior and unitary production of neurons in the
neocortex
tmp:
image: /images/cc_by.png
legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
short: CC BY (4.0)
type: journal_article
user_id: 4435EBFC-F248-11E8-B48F-1D18A9856A87
volume: 159
year: '2014'
...
---
_id: '2020'
abstract:
- lang: eng
text: The mammalian heart has long been considered a postmitotic organ, implying
that the total number of cardiomyocytes is set at birth. Analysis of cell division
in the mammalian heart is complicated by cardiomyocyte binucleation shortly after
birth, which makes it challenging to interpret traditional assays of cell turnover
[Laflamme MA, Murray CE (2011) Nature 473(7347):326–335; Bergmann O, et al. (2009)
Science 324(5923):98–102]. An elegant multi-isotope imaging-mass spectrometry
technique recently calculated the low, discrete rate of cardiomyocyte generation
in mice [Senyo SE, et al. (2013) Nature 493(7432):433–436], yet our cellular-level
understanding of postnatal cardiomyogenesis remains limited. Herein, we provide
a new line of evidence for the differentiated α-myosin heavy chain-expressing
cardiomyocyte as the cell of origin of postnatal cardiomyogenesis using the “mosaic
analysis with double markers” mouse model. We show limited, life-long, symmetric
division of cardiomyocytes as a rare event that is evident in utero but significantly
diminishes after the first month of life in mice; daughter cardiomyocytes divide
very seldom, which this study is the first to demonstrate, to our knowledge. Furthermore,
ligation of the left anterior descending coronary artery, which causes a myocardial
infarction in the mosaic analysis with double-marker mice, did not increase the
rate of cardiomyocyte division above the basal level for up to 4 wk after the
injury. The clonal analysis described here provides direct evidence of postnatal
mammalian cardiomyogenesis.
author:
- first_name: Shah
full_name: Ali, Shah
last_name: Ali
- first_name: Simon
full_name: Hippenmeyer, Simon
id: 37B36620-F248-11E8-B48F-1D18A9856A87
last_name: Hippenmeyer
orcid: 0000-0003-2279-1061
- first_name: Lily
full_name: Saadat, Lily
last_name: Saadat
- first_name: Liqun
full_name: Luo, Liqun
last_name: Luo
- first_name: Irving
full_name: Weissman, Irving
last_name: Weissman
- first_name: Reza
full_name: Ardehali, Reza
last_name: Ardehali
citation:
ama: Ali S, Hippenmeyer S, Saadat L, Luo L, Weissman I, Ardehali R. Existing cardiomyocytes
generate cardiomyocytes at a low rate after birth in mice. PNAS. 2014;111(24):8850-8855.
doi:10.1073/pnas.1408233111
apa: Ali, S., Hippenmeyer, S., Saadat, L., Luo, L., Weissman, I., & Ardehali,
R. (2014). Existing cardiomyocytes generate cardiomyocytes at a low rate after
birth in mice. PNAS. National Academy of Sciences. https://doi.org/10.1073/pnas.1408233111
chicago: Ali, Shah, Simon Hippenmeyer, Lily Saadat, Liqun Luo, Irving Weissman,
and Reza Ardehali. “Existing Cardiomyocytes Generate Cardiomyocytes at a Low Rate
after Birth in Mice.” PNAS. National Academy of Sciences, 2014. https://doi.org/10.1073/pnas.1408233111.
ieee: S. Ali, S. Hippenmeyer, L. Saadat, L. Luo, I. Weissman, and R. Ardehali, “Existing
cardiomyocytes generate cardiomyocytes at a low rate after birth in mice,” PNAS,
vol. 111, no. 24. National Academy of Sciences, pp. 8850–8855, 2014.
ista: Ali S, Hippenmeyer S, Saadat L, Luo L, Weissman I, Ardehali R. 2014. Existing
cardiomyocytes generate cardiomyocytes at a low rate after birth in mice. PNAS.
111(24), 8850–8855.
mla: Ali, Shah, et al. “Existing Cardiomyocytes Generate Cardiomyocytes at a Low
Rate after Birth in Mice.” PNAS, vol. 111, no. 24, National Academy of
Sciences, 2014, pp. 8850–55, doi:10.1073/pnas.1408233111.
short: S. Ali, S. Hippenmeyer, L. Saadat, L. Luo, I. Weissman, R. Ardehali, PNAS
111 (2014) 8850–8855.
date_created: 2018-12-11T11:55:15Z
date_published: 2014-06-17T00:00:00Z
date_updated: 2021-01-12T06:54:46Z
day: '17'
department:
- _id: SiHi
doi: 10.1073/pnas.1408233111
intvolume: ' 111'
issue: '24'
language:
- iso: eng
month: '06'
oa_version: None
page: 8850 - 8855
publication: PNAS
publication_status: published
publisher: National Academy of Sciences
publist_id: '5052'
quality_controlled: '1'
scopus_import: 1
status: public
title: Existing cardiomyocytes generate cardiomyocytes at a low rate after birth in
mice
type: journal_article
user_id: 4435EBFC-F248-11E8-B48F-1D18A9856A87
volume: 111
year: '2014'
...
---
_id: '2021'
abstract:
- lang: eng
text: Neurotrophins regulate diverse aspects of neuronal development and plasticity,
but their precise in vivo functions during neural circuit assembly in the central
brain remain unclear. We show that the neurotrophin receptor tropomyosin-related
kinase C (TrkC) is required for dendritic growth and branching of mouse cerebellar
Purkinje cells. Sparse TrkC knockout reduced dendrite complexity, but global Purkinje
cell knockout had no effect. Removal of the TrkC ligand neurotrophin-3 (NT-3)
from cerebellar granule cells, which provide major afferent input to developing
Purkinje cell dendrites, rescued the dendrite defects caused by sparse TrkC disruption
in Purkinje cells. Our data demonstrate that NT-3 from presynaptic neurons (granule
cells) is required for TrkC-dependent competitive dendrite morphogenesis in postsynaptic
neurons (Purkinje cells)—a previously unknown mechanism of neural circuit development.
author:
- first_name: Joo
full_name: William, Joo
last_name: William
- first_name: Simon
full_name: Hippenmeyer, Simon
id: 37B36620-F248-11E8-B48F-1D18A9856A87
last_name: Hippenmeyer
orcid: 0000-0003-2279-1061
- first_name: Liqun
full_name: Luo, Liqun
last_name: Luo
citation:
ama: William J, Hippenmeyer S, Luo L. Dendrite morphogenesis depends on relative
levels of NT-3/TrkC signaling. Science. 2014;346(6209):626-629. doi:10.1126/science.1258996
apa: William, J., Hippenmeyer, S., & Luo, L. (2014). Dendrite morphogenesis
depends on relative levels of NT-3/TrkC signaling. Science. American Association
for the Advancement of Science. https://doi.org/10.1126/science.1258996
chicago: William, Joo, Simon Hippenmeyer, and Liqun Luo. “Dendrite Morphogenesis
Depends on Relative Levels of NT-3/TrkC Signaling.” Science. American Association
for the Advancement of Science, 2014. https://doi.org/10.1126/science.1258996.
ieee: J. William, S. Hippenmeyer, and L. Luo, “Dendrite morphogenesis depends on
relative levels of NT-3/TrkC signaling,” Science, vol. 346, no. 6209. American
Association for the Advancement of Science, pp. 626–629, 2014.
ista: William J, Hippenmeyer S, Luo L. 2014. Dendrite morphogenesis depends on relative
levels of NT-3/TrkC signaling. Science. 346(6209), 626–629.
mla: William, Joo, et al. “Dendrite Morphogenesis Depends on Relative Levels of
NT-3/TrkC Signaling.” Science, vol. 346, no. 6209, American Association
for the Advancement of Science, 2014, pp. 626–29, doi:10.1126/science.1258996.
short: J. William, S. Hippenmeyer, L. Luo, Science 346 (2014) 626–629.
date_created: 2018-12-11T11:55:15Z
date_published: 2014-10-31T00:00:00Z
date_updated: 2021-01-12T06:54:47Z
day: '31'
department:
- _id: SiHi
doi: 10.1126/science.1258996
intvolume: ' 346'
issue: '6209'
language:
- iso: eng
main_file_link:
- open_access: '1'
url: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4631524/
month: '10'
oa: 1
oa_version: Submitted Version
page: 626 - 629
publication: Science
publication_status: published
publisher: American Association for the Advancement of Science
publist_id: '5051'
quality_controlled: '1'
scopus_import: 1
status: public
title: Dendrite morphogenesis depends on relative levels of NT-3/TrkC signaling
type: journal_article
user_id: 4435EBFC-F248-11E8-B48F-1D18A9856A87
volume: 346
year: '2014'
...
---
_id: '2027'
abstract:
- lang: eng
text: We present a general framework for applying machine-learning algorithms to
the verification of Markov decision processes (MDPs). The primary goal of these
techniques is to improve performance by avoiding an exhaustive exploration of
the state space. Our framework focuses on probabilistic reachability, which is
a core property for verification, and is illustrated through two distinct instantiations.
The first assumes that full knowledge of the MDP is available, and performs a
heuristic-driven partial exploration of the model, yielding precise lower and
upper bounds on the required probability. The second tackles the case where we
may only sample the MDP, and yields probabilistic guarantees, again in terms of
both the lower and upper bounds, which provides efficient stopping criteria for
the approximation. The latter is the first extension of statistical model checking
for unbounded properties inMDPs. In contrast with other related techniques, our
approach is not restricted to time-bounded (finite-horizon) or discounted properties,
nor does it assume any particular properties of the MDP. We also show how our
methods extend to LTL objectives. We present experimental results showing the
performance of our framework on several examples.
acknowledgement: This research was funded in part by the European Research Council
(ERC) under grant agreement 246967 (VERIWARE), by the EU FP7 project HIERATIC, by
the Czech Science Foundation grant No P202/12/P612, by EPSRC project EP/K038575/1.
alternative_title:
- LNCS
author:
- first_name: Tomáš
full_name: Brázdil, Tomáš
last_name: Brázdil
- first_name: Krishnendu
full_name: Chatterjee, Krishnendu
id: 2E5DCA20-F248-11E8-B48F-1D18A9856A87
last_name: Chatterjee
orcid: 0000-0002-4561-241X
- first_name: Martin
full_name: Chmelik, Martin
id: 3624234E-F248-11E8-B48F-1D18A9856A87
last_name: Chmelik
- first_name: Vojtěch
full_name: Forejt, Vojtěch
last_name: Forejt
- first_name: Jan
full_name: Kretinsky, Jan
id: 44CEF464-F248-11E8-B48F-1D18A9856A87
last_name: Kretinsky
orcid: 0000-0002-8122-2881
- first_name: Marta
full_name: Kwiatkowska, Marta
last_name: Kwiatkowska
- first_name: David
full_name: Parker, David
last_name: Parker
- first_name: Mateusz
full_name: Ujma, Mateusz
last_name: Ujma
citation:
ama: 'Brázdil T, Chatterjee K, Chmelik M, et al. Verification of markov decision
processes using learning algorithms. In: Cassez F, Raskin J-F, eds. Lecture
Notes in Computer Science (Including Subseries Lecture Notes in Artificial Intelligence
and Lecture Notes in Bioinformatics). Vol 8837. Society of Industrial and
Applied Mathematics; 2014:98-114. doi:10.1007/978-3-319-11936-6_8'
apa: 'Brázdil, T., Chatterjee, K., Chmelik, M., Forejt, V., Kretinsky, J., Kwiatkowska,
M., … Ujma, M. (2014). Verification of markov decision processes using learning
algorithms. In F. Cassez & J.-F. Raskin (Eds.), Lecture Notes in Computer
Science (including subseries Lecture Notes in Artificial Intelligence and Lecture
Notes in Bioinformatics) (Vol. 8837, pp. 98–114). Sydney, Australia: Society
of Industrial and Applied Mathematics. https://doi.org/10.1007/978-3-319-11936-6_8'
chicago: Brázdil, Tomáš, Krishnendu Chatterjee, Martin Chmelik, Vojtěch Forejt,
Jan Kretinsky, Marta Kwiatkowska, David Parker, and Mateusz Ujma. “Verification
of Markov Decision Processes Using Learning Algorithms.” In Lecture Notes
in Computer Science (Including Subseries Lecture Notes in Artificial Intelligence
and Lecture Notes in Bioinformatics), edited by Franck Cassez and Jean-François
Raskin, 8837:98–114. Society of Industrial and Applied Mathematics, 2014. https://doi.org/10.1007/978-3-319-11936-6_8.
ieee: T. Brázdil et al., “Verification of markov decision processes using
learning algorithms,” in Lecture Notes in Computer Science (including subseries
Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics),
Sydney, Australia, 2014, vol. 8837, pp. 98–114.
ista: 'Brázdil T, Chatterjee K, Chmelik M, Forejt V, Kretinsky J, Kwiatkowska M,
Parker D, Ujma M. 2014. Verification of markov decision processes using learning
algorithms. Lecture Notes in Computer Science (including subseries Lecture Notes
in Artificial Intelligence and Lecture Notes in Bioinformatics). ALENEX: Algorithm
Engineering and Experiments, LNCS, vol. 8837, 98–114.'
mla: Brázdil, Tomáš, et al. “Verification of Markov Decision Processes Using Learning
Algorithms.” Lecture Notes in Computer Science (Including Subseries Lecture
Notes in Artificial Intelligence and Lecture Notes in Bioinformatics), edited
by Franck Cassez and Jean-François Raskin, vol. 8837, Society of Industrial and
Applied Mathematics, 2014, pp. 98–114, doi:10.1007/978-3-319-11936-6_8.
short: T. Brázdil, K. Chatterjee, M. Chmelik, V. Forejt, J. Kretinsky, M. Kwiatkowska,
D. Parker, M. Ujma, in:, F. Cassez, J.-F. Raskin (Eds.), Lecture Notes in Computer
Science (Including Subseries Lecture Notes in Artificial Intelligence and Lecture
Notes in Bioinformatics), Society of Industrial and Applied Mathematics, 2014,
pp. 98–114.
conference:
end_date: 2014-11-07
location: Sydney, Australia
name: 'ALENEX: Algorithm Engineering and Experiments'
start_date: 2014-11-03
date_created: 2018-12-11T11:55:17Z
date_published: 2014-11-01T00:00:00Z
date_updated: 2021-01-12T06:54:49Z
day: '01'
department:
- _id: KrCh
- _id: ToHe
doi: 10.1007/978-3-319-11936-6_8
ec_funded: 1
editor:
- first_name: Franck
full_name: Cassez, Franck
last_name: Cassez
- first_name: Jean-François
full_name: Raskin, Jean-François
last_name: Raskin
intvolume: ' 8837'
language:
- iso: eng
main_file_link:
- open_access: '1'
url: http://arxiv.org/abs/1402.2967
month: '11'
oa: 1
oa_version: Submitted Version
page: 98 - 114
project:
- _id: 25EE3708-B435-11E9-9278-68D0E5697425
call_identifier: FP7
grant_number: '267989'
name: Quantitative Reactive Modeling
- _id: 26241A12-B435-11E9-9278-68D0E5697425
grant_number: '24696'
name: LIGHT-REGULATED LIGAND TRAPS FOR SPATIO-TEMPORAL INHIBITION OF CELL SIGNALING
- _id: 2581B60A-B435-11E9-9278-68D0E5697425
call_identifier: FP7
grant_number: '279307'
name: 'Quantitative Graph Games: Theory and Applications'
- _id: 25F5A88A-B435-11E9-9278-68D0E5697425
call_identifier: FWF
grant_number: S11402-N23
name: Moderne Concurrency Paradigms
- _id: 25863FF4-B435-11E9-9278-68D0E5697425
call_identifier: FWF
grant_number: S11407
name: Game Theory
- _id: 2584A770-B435-11E9-9278-68D0E5697425
call_identifier: FWF
grant_number: P 23499-N23
name: Modern Graph Algorithmic Techniques in Formal Verification
- _id: 2587B514-B435-11E9-9278-68D0E5697425
name: Microsoft Research Faculty Fellowship
publication: ' Lecture Notes in Computer Science (including subseries Lecture Notes
in Artificial Intelligence and Lecture Notes in Bioinformatics)'
publication_status: published
publisher: Society of Industrial and Applied Mathematics
publist_id: '5046'
quality_controlled: '1'
status: public
title: Verification of markov decision processes using learning algorithms
type: conference
user_id: 4435EBFC-F248-11E8-B48F-1D18A9856A87
volume: 8837
year: '2014'
...
---
_id: '2031'
abstract:
- lang: eng
text: A puzzling property of synaptic transmission, originally established at the
neuromuscular junction, is that the time course of transmitter release is independent
of the extracellular Ca2+ concentration ([Ca2+]o), whereas the rate of release
is highly [Ca2+]o-dependent. Here, we examine the time course of release at inhibitory
basket cell-Purkinje cell synapses and show that it is independent of [Ca2+]o.
Modeling of Ca2+-dependent transmitter release suggests that the invariant time
course of release critically depends on tight coupling between Ca2+ channels and
release sensors. Experiments with exogenous Ca2+ chelators reveal that channel-sensor
coupling at basket cell-Purkinje cell synapses is very tight, with a mean distance
of 10–20 nm. Thus, tight channel-sensor coupling provides a mechanistic explanation
for the apparent [Ca2+]o independence of the time course of release.
author:
- first_name: Itaru
full_name: Arai, Itaru
id: 32A73F6C-F248-11E8-B48F-1D18A9856A87
last_name: Arai
- first_name: Peter M
full_name: Jonas, Peter M
id: 353C1B58-F248-11E8-B48F-1D18A9856A87
last_name: Jonas
orcid: 0000-0001-5001-4804
citation:
ama: Arai itaru, Jonas PM. Nanodomain coupling explains Ca^2+ independence of transmitter
release time course at a fast central synapse. eLife. 2014;3. doi:10.7554/eLife.04057
apa: Arai, itaru, & Jonas, P. M. (2014). Nanodomain coupling explains Ca^2+
independence of transmitter release time course at a fast central synapse. ELife.
eLife Sciences Publications. https://doi.org/10.7554/eLife.04057
chicago: Arai, itaru, and Peter M Jonas. “Nanodomain Coupling Explains Ca^2+ Independence
of Transmitter Release Time Course at a Fast Central Synapse.” ELife. eLife
Sciences Publications, 2014. https://doi.org/10.7554/eLife.04057.
ieee: itaru Arai and P. M. Jonas, “Nanodomain coupling explains Ca^2+ independence
of transmitter release time course at a fast central synapse,” eLife, vol.
3. eLife Sciences Publications, 2014.
ista: Arai itaru, Jonas PM. 2014. Nanodomain coupling explains Ca^2+ independence
of transmitter release time course at a fast central synapse. eLife. 3.
mla: Arai, itaru, and Peter M. Jonas. “Nanodomain Coupling Explains Ca^2+ Independence
of Transmitter Release Time Course at a Fast Central Synapse.” ELife, vol.
3, eLife Sciences Publications, 2014, doi:10.7554/eLife.04057.
short: itaru Arai, P.M. Jonas, ELife 3 (2014).
date_created: 2018-12-11T11:55:19Z
date_published: 2014-12-09T00:00:00Z
date_updated: 2021-01-12T06:54:51Z
day: '09'
ddc:
- '570'
department:
- _id: PeJo
doi: 10.7554/eLife.04057
ec_funded: 1
file:
- access_level: open_access
checksum: c240f915450d4ebe8f95043a2a8c7b1a
content_type: application/pdf
creator: system
date_created: 2018-12-12T10:14:41Z
date_updated: 2020-07-14T12:45:26Z
file_id: '5094'
file_name: IST-2016-421-v1+1_e04057.full.pdf
file_size: 2239563
relation: main_file
file_date_updated: 2020-07-14T12:45:26Z
has_accepted_license: '1'
intvolume: ' 3'
language:
- iso: eng
month: '12'
oa: 1
oa_version: Submitted Version
project:
- _id: 25C26B1E-B435-11E9-9278-68D0E5697425
call_identifier: FWF
grant_number: P24909-B24
name: Mechanisms of transmitter release at GABAergic synapses
- _id: 25C0F108-B435-11E9-9278-68D0E5697425
call_identifier: FP7
grant_number: '268548'
name: Nanophysiology of fast-spiking, parvalbumin-expressing GABAergic interneurons
publication: eLife
publication_status: published
publisher: eLife Sciences Publications
publist_id: '5041'
pubrep_id: '421'
quality_controlled: '1'
scopus_import: 1
status: public
title: Nanodomain coupling explains Ca^2+ independence of transmitter release time
course at a fast central synapse
type: journal_article
user_id: 4435EBFC-F248-11E8-B48F-1D18A9856A87
volume: 3
year: '2014'
...
---
_id: '2024'
abstract:
- lang: eng
text: 'The yeast Rab5 homologue, Vps21p, is known to be involved both in the vacuolar
protein sorting (VPS) pathway from the trans-Golgi network to the vacuole, and
in the endocytic pathway from the plasma membrane to the vacuole. However, the
intracellular location at which these two pathways converge remains unclear. In
addition, the endocytic pathway is not completely blocked in yeast cells lacking
all Rab5 genes, suggesting the existence of an unidentified route that bypasses
the Rab5-dependent endocytic pathway. Here we show that convergence of the endocytic
and VPS pathways occurs upstream of the requirement for Vps21p in these pathways.
We also identify a previously unidentified endocytic pathway mediated by the AP-3
complex. Importantly, the AP-3-mediated pathway appears mostly intact in Rab5-disrupted
cells, and thus works as an alternative route to the vacuole/lysosome. We propose
that the endocytic traffic branches into two routes to reach the vacuole: a Rab5-dependent
VPS pathway and a Rab5-independent AP-3-mediated pathway.'
article_number: '3498'
author:
- first_name: Junko
full_name: Toshima, Junko
last_name: Toshima
- first_name: Show
full_name: Nishinoaki, Show
last_name: Nishinoaki
- first_name: Yoshifumi
full_name: Sato, Yoshifumi
last_name: Sato
- first_name: Wataru
full_name: Yamamoto, Wataru
last_name: Yamamoto
- first_name: Daiki
full_name: Furukawa, Daiki
last_name: Furukawa
- first_name: Daria E
full_name: Siekhaus, Daria E
id: 3D224B9E-F248-11E8-B48F-1D18A9856A87
last_name: Siekhaus
orcid: 0000-0001-8323-8353
- first_name: Akira
full_name: Sawaguchi, Akira
last_name: Sawaguchi
- first_name: Jiro
full_name: Toshima, Jiro
last_name: Toshima
citation:
ama: Toshima J, Nishinoaki S, Sato Y, et al. Bifurcation of the endocytic pathway
into Rab5-dependent and -independent transport to the vacuole. Nature Communications.
2014;5. doi:10.1038/ncomms4498
apa: Toshima, J., Nishinoaki, S., Sato, Y., Yamamoto, W., Furukawa, D., Siekhaus,
D. E., … Toshima, J. (2014). Bifurcation of the endocytic pathway into Rab5-dependent
and -independent transport to the vacuole. Nature Communications. Nature
Publishing Group. https://doi.org/10.1038/ncomms4498
chicago: Toshima, Junko, Show Nishinoaki, Yoshifumi Sato, Wataru Yamamoto, Daiki
Furukawa, Daria E Siekhaus, Akira Sawaguchi, and Jiro Toshima. “Bifurcation of
the Endocytic Pathway into Rab5-Dependent and -Independent Transport to the Vacuole.”
Nature Communications. Nature Publishing Group, 2014. https://doi.org/10.1038/ncomms4498.
ieee: J. Toshima et al., “Bifurcation of the endocytic pathway into Rab5-dependent
and -independent transport to the vacuole,” Nature Communications, vol.
5. Nature Publishing Group, 2014.
ista: Toshima J, Nishinoaki S, Sato Y, Yamamoto W, Furukawa D, Siekhaus DE, Sawaguchi
A, Toshima J. 2014. Bifurcation of the endocytic pathway into Rab5-dependent and
-independent transport to the vacuole. Nature Communications. 5, 3498.
mla: Toshima, Junko, et al. “Bifurcation of the Endocytic Pathway into Rab5-Dependent
and -Independent Transport to the Vacuole.” Nature Communications, vol.
5, 3498, Nature Publishing Group, 2014, doi:10.1038/ncomms4498.
short: J. Toshima, S. Nishinoaki, Y. Sato, W. Yamamoto, D. Furukawa, D.E. Siekhaus,
A. Sawaguchi, J. Toshima, Nature Communications 5 (2014).
date_created: 2018-12-11T11:55:16Z
date_published: 2014-03-25T00:00:00Z
date_updated: 2021-01-12T06:54:48Z
day: '25'
ddc:
- '570'
department:
- _id: DaSi
doi: 10.1038/ncomms4498
file:
- access_level: open_access
checksum: 614fb6579c86d1f95bdd95eeb9ab01b0
content_type: application/pdf
creator: system
date_created: 2018-12-12T10:11:11Z
date_updated: 2020-07-14T12:45:25Z
file_id: '4864'
file_name: IST-2016-616-v1+1_DaSi_Bifurcation_Postprint.pdf
file_size: 4803515
relation: main_file
file_date_updated: 2020-07-14T12:45:25Z
has_accepted_license: '1'
intvolume: ' 5'
language:
- iso: eng
month: '03'
oa: 1
oa_version: Submitted Version
publication: Nature Communications
publication_status: published
publisher: Nature Publishing Group
publist_id: '5048'
pubrep_id: '616'
quality_controlled: '1'
scopus_import: 1
status: public
title: Bifurcation of the endocytic pathway into Rab5-dependent and -independent transport
to the vacuole
type: journal_article
user_id: 4435EBFC-F248-11E8-B48F-1D18A9856A87
volume: 5
year: '2014'
...
---
_id: '2028'
abstract:
- lang: eng
text: 'Understanding the dynamics of noisy neurons remains an important challenge
in neuroscience. Here, we describe a simple probabilistic model that accurately
describes the firing behavior in a large class (type II) of neurons. To demonstrate
the usefulness of this model, we show how it accurately predicts the interspike
interval (ISI) distributions, bursting patterns and mean firing rates found by:
(1) simulations of the classic Hodgkin-Huxley model with channel noise, (2) experimental
data from squid giant axon with a noisy input current and (3) experimental data
on noisy firing from a neuron within the suprachiasmatic nucleus (SCN). This simple
model has 6 parameters, however, in some cases, two of these parameters are coupled
and only 5 parameters account for much of the known behavior. From these parameters,
many properties of spiking can be found through simple calculation. Thus, we show
how the complex effects of noise can be understood through a simple and general
probabilistic model.'
acknowledgement: 'This work is supported by AFOSR grant FA 9550-11-1-0165, program
grant RPG 24/2012 from the Human Frontiers of Science (DBF) and travel support from
the European Commission Marie Curie International Reintegration Grant PIRG04-GA-2008-239429
(KB). DP was supported by NIHR01 GM104987 and the Wyss Institute of Biologically
Inspired Engineering. '
article_processing_charge: No
author:
- first_name: Katarina
full_name: Bodova, Katarina
id: 2BA24EA0-F248-11E8-B48F-1D18A9856A87
last_name: Bodova
orcid: 0000-0002-7214-0171
- first_name: David
full_name: Paydarfar, David
last_name: Paydarfar
- first_name: Daniel
full_name: Forger, Daniel
last_name: Forger
citation:
ama: Bodova K, Paydarfar D, Forger D. Characterizing spiking in noisy type II neurons.
Journal of Theoretical Biology. 2014;365:40-54. doi:10.1016/j.jtbi.2014.09.041
apa: Bodova, K., Paydarfar, D., & Forger, D. (2014). Characterizing spiking
in noisy type II neurons. Journal of Theoretical Biology. Academic Press.
https://doi.org/10.1016/j.jtbi.2014.09.041
chicago: Bodova, Katarina, David Paydarfar, and Daniel Forger. “Characterizing Spiking
in Noisy Type II Neurons.” Journal of Theoretical Biology. Academic Press,
2014. https://doi.org/10.1016/j.jtbi.2014.09.041.
ieee: K. Bodova, D. Paydarfar, and D. Forger, “Characterizing spiking in noisy type
II neurons,” Journal of Theoretical Biology, vol. 365. Academic Press,
pp. 40–54, 2014.
ista: Bodova K, Paydarfar D, Forger D. 2014. Characterizing spiking in noisy type
II neurons. Journal of Theoretical Biology. 365, 40–54.
mla: Bodova, Katarina, et al. “Characterizing Spiking in Noisy Type II Neurons.”
Journal of Theoretical Biology, vol. 365, Academic Press, 2014, pp. 40–54,
doi:10.1016/j.jtbi.2014.09.041.
short: K. Bodova, D. Paydarfar, D. Forger, Journal of Theoretical Biology 365 (2014)
40–54.
date_created: 2018-12-11T11:55:18Z
date_published: 2014-10-12T00:00:00Z
date_updated: 2022-08-25T14:00:47Z
day: '12'
ddc:
- '570'
department:
- _id: GaTk
doi: 10.1016/j.jtbi.2014.09.041
file:
- access_level: open_access
checksum: a9dbae18d3233b3dab6944fd3f2cd49e
content_type: application/pdf
creator: system
date_created: 2018-12-12T10:17:58Z
date_updated: 2020-07-14T12:45:25Z
file_id: '5316'
file_name: IST-2016-444-v1+1_1-s2.0-S0022519314005888-main.pdf
file_size: 2679222
relation: main_file
file_date_updated: 2020-07-14T12:45:25Z
has_accepted_license: '1'
intvolume: ' 365'
language:
- iso: eng
license: https://creativecommons.org/licenses/by-nc-nd/4.0/
month: '10'
oa: 1
oa_version: Published Version
page: 40 - 54
publication: ' Journal of Theoretical Biology'
publication_status: published
publisher: Academic Press
publist_id: '5043'
pubrep_id: '444'
quality_controlled: '1'
related_material:
link:
- relation: erratum
url: https://doi.org/10.1016/j.jtbi.2015.03.013
scopus_import: '1'
status: public
title: Characterizing spiking in noisy type II neurons
tmp:
image: /images/cc_by_nc_nd.png
legal_code_url: https://creativecommons.org/licenses/by-nc-nd/4.0/legalcode
name: Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International
(CC BY-NC-ND 4.0)
short: CC BY-NC-ND (4.0)
type: journal_article
user_id: 3E5EF7F0-F248-11E8-B48F-1D18A9856A87
volume: 365
year: '2014'
...
---
_id: '2026'
abstract:
- lang: eng
text: 'We present a tool for translating LTL formulae into deterministic ω-automata.
It is the first tool that covers the whole LTL that does not use Safra’s determinization
or any of its variants. This leads to smaller automata. There are several outputs
of the tool: firstly, deterministic Rabin automata, which are the standard input
for probabilistic model checking, e.g. for the probabilistic model-checker PRISM;
secondly, deterministic generalized Rabin automata, which can also be used for
probabilistic model checking and are sometimes by orders of magnitude smaller.
We also link our tool to PRISM and show that this leads to a significant speed-up
of probabilistic LTL model checking, especially with the generalized Rabin automata.'
acknowledgement: "Sponsor: P202/12/G061; GACR; Czech Science Foundation\r\n\r\n"
alternative_title:
- LNCS
author:
- first_name: Zuzana
full_name: Komárková, Zuzana
last_name: Komárková
- first_name: Jan
full_name: Kretinsky, Jan
id: 44CEF464-F248-11E8-B48F-1D18A9856A87
last_name: Kretinsky
orcid: 0000-0002-8122-2881
citation:
ama: 'Komárková Z, Kretinsky J. Rabinizer 3: Safraless translation of ltl to small
deterministic automata. In: Cassez F, Raskin J-F, eds. Lecture Notes in Computer
Science (Including Subseries Lecture Notes in Artificial Intelligence and Lecture
Notes in Bioinformatics). Vol 8837. Springer; 2014:235-241. doi:10.1007/978-3-319-11936-6_17'
apa: 'Komárková, Z., & Kretinsky, J. (2014). Rabinizer 3: Safraless translation
of ltl to small deterministic automata. In F. Cassez & J.-F. Raskin (Eds.),
Lecture Notes in Computer Science (including subseries Lecture Notes in Artificial
Intelligence and Lecture Notes in Bioinformatics) (Vol. 8837, pp. 235–241).
Sydney, Australia: Springer. https://doi.org/10.1007/978-3-319-11936-6_17'
chicago: 'Komárková, Zuzana, and Jan Kretinsky. “Rabinizer 3: Safraless Translation
of Ltl to Small Deterministic Automata.” In Lecture Notes in Computer Science
(Including Subseries Lecture Notes in Artificial Intelligence and Lecture Notes
in Bioinformatics), edited by Franck Cassez and Jean-François Raskin, 8837:235–41.
Springer, 2014. https://doi.org/10.1007/978-3-319-11936-6_17.'
ieee: 'Z. Komárková and J. Kretinsky, “Rabinizer 3: Safraless translation of ltl
to small deterministic automata,” in Lecture Notes in Computer Science (including
subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics),
Sydney, Australia, 2014, vol. 8837, pp. 235–241.'
ista: 'Komárková Z, Kretinsky J. 2014. Rabinizer 3: Safraless translation of ltl
to small deterministic automata. Lecture Notes in Computer Science (including
subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics).
ATVA: Automated Technology for Verification and Analysis, LNCS, vol. 8837, 235–241.'
mla: 'Komárková, Zuzana, and Jan Kretinsky. “Rabinizer 3: Safraless Translation
of Ltl to Small Deterministic Automata.” Lecture Notes in Computer Science
(Including Subseries Lecture Notes in Artificial Intelligence and Lecture Notes
in Bioinformatics), edited by Franck Cassez and Jean-François Raskin, vol.
8837, Springer, 2014, pp. 235–41, doi:10.1007/978-3-319-11936-6_17.'
short: Z. Komárková, J. Kretinsky, in:, F. Cassez, J.-F. Raskin (Eds.), Lecture
Notes in Computer Science (Including Subseries Lecture Notes in Artificial Intelligence
and Lecture Notes in Bioinformatics), Springer, 2014, pp. 235–241.
conference:
end_date: 2014-11-07
location: Sydney, Australia
name: 'ATVA: Automated Technology for Verification and Analysis'
start_date: 2014-11-03
date_created: 2018-12-11T11:55:17Z
date_published: 2014-01-01T00:00:00Z
date_updated: 2021-01-12T06:54:49Z
day: '01'
department:
- _id: ToHe
doi: 10.1007/978-3-319-11936-6_17
ec_funded: 1
editor:
- first_name: Franck
full_name: Cassez, Franck
last_name: Cassez
- first_name: Jean-François
full_name: Raskin, Jean-François
last_name: Raskin
intvolume: ' 8837'
language:
- iso: eng
month: '01'
oa_version: None
page: 235 - 241
project:
- _id: 25EE3708-B435-11E9-9278-68D0E5697425
call_identifier: FP7
grant_number: '267989'
name: Quantitative Reactive Modeling
- _id: 25F5A88A-B435-11E9-9278-68D0E5697425
call_identifier: FWF
grant_number: S11402-N23
name: Moderne Concurrency Paradigms
publication: Lecture Notes in Computer Science (including subseries Lecture Notes
in Artificial Intelligence and Lecture Notes in Bioinformatics)
publication_status: published
publisher: Springer
publist_id: '5045'
quality_controlled: '1'
status: public
title: 'Rabinizer 3: Safraless translation of ltl to small deterministic automata'
type: conference
user_id: 4435EBFC-F248-11E8-B48F-1D18A9856A87
volume: 8837
year: '2014'
...
---
_id: '2029'
abstract:
- lang: eng
text: Spin-wave theory is a key ingredient in our comprehension of quantum spin
systems, and is used successfully for understanding a wide range of magnetic phenomena,
including magnon condensation and stability of patterns in dipolar systems. Nevertheless,
several decades of research failed to establish the validity of spin-wave theory
rigorously, even for the simplest models of quantum spins. A rigorous justification
of the method for the three-dimensional quantum Heisenberg ferromagnet at low
temperatures is presented here. We derive sharp bounds on its free energy by combining
a bosonic formulation of the model introduced by Holstein and Primakoff with probabilistic
estimates and operator inequalities.
acknowledgement: 239694; ERC; European Research Council
article_number: '20003'
author:
- first_name: Michele
full_name: Correggi, Michele
last_name: Correggi
- first_name: Alessandro
full_name: Giuliani, Alessandro
last_name: Giuliani
- first_name: Robert
full_name: Seiringer, Robert
id: 4AFD0470-F248-11E8-B48F-1D18A9856A87
last_name: Seiringer
orcid: 0000-0002-6781-0521
citation:
ama: Correggi M, Giuliani A, Seiringer R. Validity of spin-wave theory for the quantum
Heisenberg model. EPL. 2014;108(2). doi:10.1209/0295-5075/108/20003
apa: Correggi, M., Giuliani, A., & Seiringer, R. (2014). Validity of spin-wave
theory for the quantum Heisenberg model. EPL. IOP Publishing Ltd. https://doi.org/10.1209/0295-5075/108/20003
chicago: Correggi, Michele, Alessandro Giuliani, and Robert Seiringer. “Validity
of Spin-Wave Theory for the Quantum Heisenberg Model.” EPL. IOP Publishing
Ltd., 2014. https://doi.org/10.1209/0295-5075/108/20003.
ieee: M. Correggi, A. Giuliani, and R. Seiringer, “Validity of spin-wave theory
for the quantum Heisenberg model,” EPL, vol. 108, no. 2. IOP Publishing
Ltd., 2014.
ista: Correggi M, Giuliani A, Seiringer R. 2014. Validity of spin-wave theory for
the quantum Heisenberg model. EPL. 108(2), 20003.
mla: Correggi, Michele, et al. “Validity of Spin-Wave Theory for the Quantum Heisenberg
Model.” EPL, vol. 108, no. 2, 20003, IOP Publishing Ltd., 2014, doi:10.1209/0295-5075/108/20003.
short: M. Correggi, A. Giuliani, R. Seiringer, EPL 108 (2014).
date_created: 2018-12-11T11:55:18Z
date_published: 2014-10-13T00:00:00Z
date_updated: 2021-01-12T06:54:50Z
day: '13'
department:
- _id: RoSe
doi: 10.1209/0295-5075/108/20003
intvolume: ' 108'
issue: '2'
language:
- iso: eng
main_file_link:
- open_access: '1'
url: http://arxiv.org/abs/1404.4717
month: '10'
oa: 1
oa_version: Submitted Version
publication: EPL
publication_status: published
publisher: IOP Publishing Ltd.
publist_id: '5044'
quality_controlled: '1'
scopus_import: 1
status: public
title: Validity of spin-wave theory for the quantum Heisenberg model
type: journal_article
user_id: 4435EBFC-F248-11E8-B48F-1D18A9856A87
volume: 108
year: '2014'
...
---
_id: '2033'
abstract:
- lang: eng
text: 'The learning with privileged information setting has recently attracted a
lot of attention within the machine learning community, as it allows the integration
of additional knowledge into the training process of a classifier, even when this
comes in the form of a data modality that is not available at test time. Here,
we show that privileged information can naturally be treated as noise in the latent
function of a Gaussian process classifier (GPC). That is, in contrast to the standard
GPC setting, the latent function is not just a nuisance but a feature: it becomes
a natural measure of confidence about the training data by modulating the slope
of the GPC probit likelihood function. Extensive experiments on public datasets
show that the proposed GPC method using privileged noise, called GPC+, improves
over a standard GPC without privileged knowledge, and also over the current state-of-the-art
SVM-based method, SVM+. Moreover, we show that advanced neural networks and deep
learning methods can be compressed as privileged information.'
author:
- first_name: Daniel
full_name: Hernandez Lobato, Daniel
last_name: Hernandez Lobato
- first_name: Viktoriia
full_name: Sharmanska, Viktoriia
id: 2EA6D09E-F248-11E8-B48F-1D18A9856A87
last_name: Sharmanska
orcid: 0000-0003-0192-9308
- first_name: Kristian
full_name: Kersting, Kristian
last_name: Kersting
- first_name: Christoph
full_name: Lampert, Christoph
id: 40C20FD2-F248-11E8-B48F-1D18A9856A87
last_name: Lampert
orcid: 0000-0001-8622-7887
- first_name: Novi
full_name: Quadrianto, Novi
last_name: Quadrianto
citation:
ama: 'Hernandez Lobato D, Sharmanska V, Kersting K, Lampert C, Quadrianto N. Mind
the nuisance: Gaussian process classification using privileged noise. In: Advances
in Neural Information Processing Systems. Vol 1. Neural Information Processing
Systems; 2014:837-845.'
apa: 'Hernandez Lobato, D., Sharmanska, V., Kersting, K., Lampert, C., & Quadrianto,
N. (2014). Mind the nuisance: Gaussian process classification using privileged
noise. In Advances in Neural Information Processing Systems (Vol. 1, pp.
837–845). Montreal, Canada: Neural Information Processing Systems.'
chicago: 'Hernandez Lobato, Daniel, Viktoriia Sharmanska, Kristian Kersting, Christoph
Lampert, and Novi Quadrianto. “Mind the Nuisance: Gaussian Process Classification
Using Privileged Noise.” In Advances in Neural Information Processing Systems,
1:837–45. Neural Information Processing Systems, 2014.'
ieee: 'D. Hernandez Lobato, V. Sharmanska, K. Kersting, C. Lampert, and N. Quadrianto,
“Mind the nuisance: Gaussian process classification using privileged noise,” in
Advances in Neural Information Processing Systems, Montreal, Canada, 2014,
vol. 1, no. January, pp. 837–845.'
ista: 'Hernandez Lobato D, Sharmanska V, Kersting K, Lampert C, Quadrianto N. 2014.
Mind the nuisance: Gaussian process classification using privileged noise. Advances
in Neural Information Processing Systems. NIPS: Neural Information Processing
Systems vol. 1, 837–845.'
mla: 'Hernandez Lobato, Daniel, et al. “Mind the Nuisance: Gaussian Process Classification
Using Privileged Noise.” Advances in Neural Information Processing Systems,
vol. 1, no. January, Neural Information Processing Systems, 2014, pp. 837–45.'
short: D. Hernandez Lobato, V. Sharmanska, K. Kersting, C. Lampert, N. Quadrianto,
in:, Advances in Neural Information Processing Systems, Neural Information Processing
Systems, 2014, pp. 837–845.
conference:
end_date: 2014-12-13
location: Montreal, Canada
name: 'NIPS: Neural Information Processing Systems'
start_date: 2014-12-08
date_created: 2018-12-11T11:55:20Z
date_published: 2014-12-08T00:00:00Z
date_updated: 2023-02-23T10:25:24Z
day: '08'
department:
- _id: ChLa
intvolume: ' 1'
issue: January
language:
- iso: eng
main_file_link:
- open_access: '1'
url: https://papers.nips.cc/paper/5373-mind-the-nuisance-gaussian-process-classification-using-privileged-noise
month: '12'
oa: 1
oa_version: Submitted Version
page: 837-845
publication: Advances in Neural Information Processing Systems
publication_status: published
publisher: Neural Information Processing Systems
publist_id: '5038'
quality_controlled: '1'
scopus_import: 1
status: public
title: 'Mind the nuisance: Gaussian process classification using privileged noise'
type: conference
user_id: 4435EBFC-F248-11E8-B48F-1D18A9856A87
volume: 1
year: '2014'
...
---
_id: '2032'
abstract:
- lang: eng
text: As light-based control of fundamental signaling pathways is becoming a reality,
the field of optogenetics is rapidly moving beyond neuroscience. We have recently
developed receptor tyrosine kinases that are activated by light and control cell
proliferation, epithelial–mesenchymal transition, and angiogenic sprouting—cell
behaviors central to cancer progression.
article_number: e964045
author:
- first_name: Álvaro
full_name: Inglés Prieto, Álvaro
id: 2A9DB292-F248-11E8-B48F-1D18A9856A87
last_name: Inglés Prieto
orcid: 0000-0002-5409-8571
- first_name: Eva
full_name: Gschaider-Reichhart, Eva
id: 3FEE232A-F248-11E8-B48F-1D18A9856A87
last_name: Gschaider-Reichhart
orcid: 0000-0002-7218-7738
- first_name: Karin
full_name: Schelch, Karin
last_name: Schelch
- first_name: Harald L
full_name: Janovjak, Harald L
id: 33BA6C30-F248-11E8-B48F-1D18A9856A87
last_name: Janovjak
orcid: 0000-0002-8023-9315
- first_name: Michael
full_name: Grusch, Michael
last_name: Grusch
citation:
ama: 'Inglés Prieto Á, Gschaider-Reichhart E, Schelch K, Janovjak HL, Grusch M.
The optogenetic promise for oncology: Episode I. Molecular and Cellular Oncology.
2014;1(4). doi:10.4161/23723548.2014.964045'
apa: 'Inglés Prieto, Á., Gschaider-Reichhart, E., Schelch, K., Janovjak, H. L.,
& Grusch, M. (2014). The optogenetic promise for oncology: Episode I. Molecular
and Cellular Oncology. Taylor & Francis. https://doi.org/10.4161/23723548.2014.964045'
chicago: 'Inglés Prieto, Álvaro, Eva Gschaider-Reichhart, Karin Schelch, Harald
L Janovjak, and Michael Grusch. “The Optogenetic Promise for Oncology: Episode
I.” Molecular and Cellular Oncology. Taylor & Francis, 2014. https://doi.org/10.4161/23723548.2014.964045.'
ieee: 'Á. Inglés Prieto, E. Gschaider-Reichhart, K. Schelch, H. L. Janovjak, and
M. Grusch, “The optogenetic promise for oncology: Episode I,” Molecular and
Cellular Oncology, vol. 1, no. 4. Taylor & Francis, 2014.'
ista: 'Inglés Prieto Á, Gschaider-Reichhart E, Schelch K, Janovjak HL, Grusch M.
2014. The optogenetic promise for oncology: Episode I. Molecular and Cellular
Oncology. 1(4), e964045.'
mla: 'Inglés Prieto, Álvaro, et al. “The Optogenetic Promise for Oncology: Episode
I.” Molecular and Cellular Oncology, vol. 1, no. 4, e964045, Taylor &
Francis, 2014, doi:10.4161/23723548.2014.964045.'
short: Á. Inglés Prieto, E. Gschaider-Reichhart, K. Schelch, H.L. Janovjak, M. Grusch,
Molecular and Cellular Oncology 1 (2014).
date_created: 2018-12-11T11:55:19Z
date_published: 2014-12-31T00:00:00Z
date_updated: 2021-01-12T06:54:51Z
day: '31'
ddc:
- '570'
department:
- _id: HaJa
doi: 10.4161/23723548.2014.964045
file:
- access_level: open_access
checksum: 44e17ad40577ab46eb602e88a8b0b8fd
content_type: application/pdf
creator: kschuh
date_created: 2019-05-16T13:39:11Z
date_updated: 2020-07-14T12:45:26Z
file_id: '6464'
file_name: 2014_Taylor_Alvaro.pdf
file_size: 1765933
relation: main_file
file_date_updated: 2020-07-14T12:45:26Z
has_accepted_license: '1'
intvolume: ' 1'
issue: '4'
language:
- iso: eng
license: https://creativecommons.org/licenses/by-nc/4.0/
month: '12'
oa: 1
oa_version: Published Version
publication: Molecular and Cellular Oncology
publication_status: published
publisher: Taylor & Francis
publist_id: '5040'
quality_controlled: '1'
scopus_import: 1
status: public
title: 'The optogenetic promise for oncology: Episode I'
tmp:
image: /images/cc_by_nc.png
legal_code_url: https://creativecommons.org/licenses/by-nc/4.0/legalcode
name: Creative Commons Attribution-NonCommercial 4.0 International (CC BY-NC 4.0)
short: CC BY-NC (4.0)
type: journal_article
user_id: 3E5EF7F0-F248-11E8-B48F-1D18A9856A87
volume: 1
year: '2014'
...
---
_id: '2045'
abstract:
- lang: eng
text: 'We introduce and study a new notion of enhanced chosen-ciphertext security
(ECCA) for public-key encryption. Loosely speaking, in the ECCA security experiment,
the decryption oracle provided to the adversary is augmented to return not only
the output of the decryption algorithm on a queried ciphertext but also of a randomness-recovery
algorithm associated to the scheme. Our results mainly concern the case where
the randomness-recovery algorithm is efficient. We provide constructions of ECCA-secure
encryption from adaptive trapdoor functions as defined by Kiltz et al. (EUROCRYPT
2010), resulting in ECCA encryption from standard number-theoretic assumptions.
We then give two applications of ECCA-secure encryption: (1) We use it as a unifying
concept in showing equivalence of adaptive trapdoor functions and tag-based adaptive
trapdoor functions, resolving an open question of Kiltz et al. (2) We show that
ECCA-secure encryption can be used to securely realize an approach to public-key
encryption with non-interactive opening (PKENO) originally suggested by Damgård
and Thorbek (EUROCRYPT 2007), resulting in new and practical PKENO schemes quite
different from those in prior work. Our results demonstrate that ECCA security
is of both practical and theoretical interest.'
acknowledgement: The second author was supported by EPSRC grant EP/H043454/1.
alternative_title:
- LNCS
author:
- first_name: Dana
full_name: Dachman Soled, Dana
last_name: Dachman Soled
- first_name: Georg
full_name: Fuchsbauer, Georg
id: 46B4C3EE-F248-11E8-B48F-1D18A9856A87
last_name: Fuchsbauer
- first_name: Payman
full_name: Mohassel, Payman
last_name: Mohassel
- first_name: Adam
full_name: O’Neill, Adam
last_name: O’Neill
citation:
ama: 'Dachman Soled D, Fuchsbauer G, Mohassel P, O’Neill A. Enhanced chosen-ciphertext
security and applications. In: Krawczyk H, ed. Lecture Notes in Computer Science
(Including Subseries Lecture Notes in Artificial Intelligence and Lecture Notes
in Bioinformatics). Vol 8383. Springer; 2014:329-344. doi:10.1007/978-3-642-54631-0_19'
apa: 'Dachman Soled, D., Fuchsbauer, G., Mohassel, P., & O’Neill, A. (2014).
Enhanced chosen-ciphertext security and applications. In H. Krawczyk (Ed.), Lecture
Notes in Computer Science (including subseries Lecture Notes in Artificial Intelligence
and Lecture Notes in Bioinformatics) (Vol. 8383, pp. 329–344). Buenos Aires,
Argentina: Springer. https://doi.org/10.1007/978-3-642-54631-0_19'
chicago: Dachman Soled, Dana, Georg Fuchsbauer, Payman Mohassel, and Adam O’Neill.
“Enhanced Chosen-Ciphertext Security and Applications.” In Lecture Notes in
Computer Science (Including Subseries Lecture Notes in Artificial Intelligence
and Lecture Notes in Bioinformatics), edited by Hugo Krawczyk, 8383:329–44.
Springer, 2014. https://doi.org/10.1007/978-3-642-54631-0_19.
ieee: D. Dachman Soled, G. Fuchsbauer, P. Mohassel, and A. O’Neill, “Enhanced chosen-ciphertext
security and applications,” in Lecture Notes in Computer Science (including
subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics),
Buenos Aires, Argentina, 2014, vol. 8383, pp. 329–344.
ista: 'Dachman Soled D, Fuchsbauer G, Mohassel P, O’Neill A. 2014. Enhanced chosen-ciphertext
security and applications. Lecture Notes in Computer Science (including subseries
Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics).
PKC: Public Key Crypography, LNCS, vol. 8383, 329–344.'
mla: Dachman Soled, Dana, et al. “Enhanced Chosen-Ciphertext Security and Applications.”
Lecture Notes in Computer Science (Including Subseries Lecture Notes in Artificial
Intelligence and Lecture Notes in Bioinformatics), edited by Hugo Krawczyk,
vol. 8383, Springer, 2014, pp. 329–44, doi:10.1007/978-3-642-54631-0_19.
short: D. Dachman Soled, G. Fuchsbauer, P. Mohassel, A. O’Neill, in:, H. Krawczyk
(Ed.), Lecture Notes in Computer Science (Including Subseries Lecture Notes in
Artificial Intelligence and Lecture Notes in Bioinformatics), Springer, 2014,
pp. 329–344.
conference:
end_date: 2014-03-28
location: Buenos Aires, Argentina
name: 'PKC: Public Key Crypography'
start_date: 2014-03-26
date_created: 2018-12-11T11:55:24Z
date_published: 2014-01-01T00:00:00Z
date_updated: 2021-01-12T06:54:57Z
day: '01'
department:
- _id: KrPi
doi: 10.1007/978-3-642-54631-0_19
ec_funded: 1
editor:
- first_name: Hugo
full_name: Krawczyk, Hugo
last_name: Krawczyk
intvolume: ' 8383'
language:
- iso: eng
main_file_link:
- open_access: '1'
url: https://eprint.iacr.org/2012/543
month: '01'
oa: 1
oa_version: Submitted Version
page: 329 - 344
project:
- _id: 258C570E-B435-11E9-9278-68D0E5697425
call_identifier: FP7
grant_number: '259668'
name: Provable Security for Physical Cryptography
publication: Lecture Notes in Computer Science (including subseries Lecture Notes
in Artificial Intelligence and Lecture Notes in Bioinformatics)
publication_status: published
publisher: Springer
publist_id: '5006'
quality_controlled: '1'
scopus_import: 1
status: public
title: Enhanced chosen-ciphertext security and applications
type: conference
user_id: 4435EBFC-F248-11E8-B48F-1D18A9856A87
volume: 8383
year: '2014'
...
---
_id: '2042'
abstract:
- lang: eng
text: 'Background: CRISPR is a microbial immune system likely to be involved in
host-parasite coevolution. It functions using target sequences encoded by the
bacterial genome, which interfere with invading nucleic acids using a homology-dependent
system. The system also requires protospacer associated motifs (PAMs), short motifs
close to the target sequence that are required for interference in CRISPR types
I and II. Here, we investigate whether PAMs are depleted in phage genomes due
to selection pressure to escape recognition.Results: To this end, we analyzed
two data sets. Phages infecting all bacterial hosts were analyzed first, followed
by a detailed analysis of phages infecting the genus Streptococcus, where PAMs
are best understood. We use two different measures of motif underrepresentation
that control for codon bias and the frequency of submotifs. We compare phages
infecting species with a particular CRISPR type to those infecting species without
that type. Since only known PAMs were investigated, the analysis is restricted
to CRISPR types I-C and I-E and in Streptococcus to types I-C and II. We found
evidence for PAM depletion in Streptococcus phages infecting hosts with CRISPR
type I-C, in Vibrio phages infecting hosts with CRISPR type I-E and in Streptococcus
thermopilus phages infecting hosts with type II-A, known as CRISPR3.Conclusions:
The observed motif depletion in phages with hosts having CRISPR can be attributed
to selection rather than to mutational bias, as mutational bias should affect
the phages of all hosts. This observation implies that the CRISPR system has been
efficient in the groups discussed here.'
article_number: '663'
author:
- first_name: Anne
full_name: Kupczok, Anne
id: 2BB22BC2-F248-11E8-B48F-1D18A9856A87
last_name: Kupczok
- first_name: Jonathan P
full_name: Bollback, Jonathan P
id: 2C6FA9CC-F248-11E8-B48F-1D18A9856A87
last_name: Bollback
orcid: 0000-0002-4624-4612
citation:
ama: Kupczok A, Bollback JP. Motif depletion in bacteriophages infecting hosts with
CRISPR systems. BMC Genomics. 2014;15(1). doi:10.1186/1471-2164-15-663
apa: Kupczok, A., & Bollback, J. P. (2014). Motif depletion in bacteriophages
infecting hosts with CRISPR systems. BMC Genomics. BioMed Central. https://doi.org/10.1186/1471-2164-15-663
chicago: Kupczok, Anne, and Jonathan P Bollback. “Motif Depletion in Bacteriophages
Infecting Hosts with CRISPR Systems.” BMC Genomics. BioMed Central, 2014.
https://doi.org/10.1186/1471-2164-15-663.
ieee: A. Kupczok and J. P. Bollback, “Motif depletion in bacteriophages infecting
hosts with CRISPR systems,” BMC Genomics, vol. 15, no. 1. BioMed Central,
2014.
ista: Kupczok A, Bollback JP. 2014. Motif depletion in bacteriophages infecting
hosts with CRISPR systems. BMC Genomics. 15(1), 663.
mla: Kupczok, Anne, and Jonathan P. Bollback. “Motif Depletion in Bacteriophages
Infecting Hosts with CRISPR Systems.” BMC Genomics, vol. 15, no. 1, 663,
BioMed Central, 2014, doi:10.1186/1471-2164-15-663.
short: A. Kupczok, J.P. Bollback, BMC Genomics 15 (2014).
date_created: 2018-12-11T11:55:23Z
date_published: 2014-08-08T00:00:00Z
date_updated: 2021-01-12T06:54:56Z
day: '08'
ddc:
- '570'
department:
- _id: JoBo
doi: 10.1186/1471-2164-15-663
file:
- access_level: open_access
checksum: 3f6d2776b90a842a28359cc957d3d04b
content_type: application/pdf
creator: system
date_created: 2018-12-12T10:11:24Z
date_updated: 2020-07-14T12:45:26Z
file_id: '4878'
file_name: IST-2015-396-v1+1_1471-2164-15-663.pdf
file_size: 1489769
relation: main_file
file_date_updated: 2020-07-14T12:45:26Z
has_accepted_license: '1'
intvolume: ' 15'
issue: '1'
language:
- iso: eng
license: https://creativecommons.org/publicdomain/zero/1.0/
month: '08'
oa: 1
oa_version: Published Version
publication: BMC Genomics
publication_status: published
publisher: BioMed Central
publist_id: '5009'
pubrep_id: '396'
quality_controlled: '1'
scopus_import: 1
status: public
title: Motif depletion in bacteriophages infecting hosts with CRISPR systems
tmp:
image: /images/cc_0.png
legal_code_url: https://creativecommons.org/publicdomain/zero/1.0/legalcode
name: Creative Commons Public Domain Dedication (CC0 1.0)
short: CC0 (1.0)
type: journal_article
user_id: 4435EBFC-F248-11E8-B48F-1D18A9856A87
volume: 15
year: '2014'
...
---
_id: '2043'
abstract:
- lang: eng
text: Persistent homology is a popular and powerful tool for capturing topological
features of data. Advances in algorithms for computing persistent homology have
reduced the computation time drastically – as long as the algorithm does not exhaust
the available memory. Following up on a recently presented parallel method for
persistence computation on shared memory systems [1], we demonstrate that a simple
adaption of the standard reduction algorithm leads to a variant for distributed
systems. Our algorithmic design ensures that the data is distributed over the
nodes without redundancy; this permits the computation of much larger instances
than on a single machine. Moreover, we observe that the parallelism at least compensates
for the overhead caused by communication between nodes, and often even speeds
up the computation compared to sequential and even parallel shared memory algorithms.
In our experiments, we were able to compute the persistent homology of filtrations
with more than a billion (109) elements within seconds on a cluster with 32 nodes
using less than 6GB of memory per node.
author:
- first_name: Ulrich
full_name: Bauer, Ulrich
id: 2ADD483A-F248-11E8-B48F-1D18A9856A87
last_name: Bauer
orcid: 0000-0002-9683-0724
- first_name: Michael
full_name: Kerber, Michael
last_name: Kerber
orcid: 0000-0002-8030-9299
- first_name: Jan
full_name: Reininghaus, Jan
id: 4505473A-F248-11E8-B48F-1D18A9856A87
last_name: Reininghaus
citation:
ama: 'Bauer U, Kerber M, Reininghaus J. Distributed computation of persistent homology.
In: McGeoch C, Meyer U, eds. Proceedings of the Workshop on Algorithm Engineering
and Experiments. Society of Industrial and Applied Mathematics; 2014:31-38.
doi:10.1137/1.9781611973198.4'
apa: 'Bauer, U., Kerber, M., & Reininghaus, J. (2014). Distributed computation
of persistent homology. In C. McGeoch & U. Meyer (Eds.), Proceedings of
the Workshop on Algorithm Engineering and Experiments (pp. 31–38). Portland,
USA: Society of Industrial and Applied Mathematics. https://doi.org/10.1137/1.9781611973198.4'
chicago: Bauer, Ulrich, Michael Kerber, and Jan Reininghaus. “Distributed Computation
of Persistent Homology.” In Proceedings of the Workshop on Algorithm Engineering
and Experiments, edited by Catherine McGeoch and Ulrich Meyer, 31–38. Society
of Industrial and Applied Mathematics, 2014. https://doi.org/10.1137/1.9781611973198.4.
ieee: U. Bauer, M. Kerber, and J. Reininghaus, “Distributed computation of persistent
homology,” in Proceedings of the Workshop on Algorithm Engineering and Experiments,
Portland, USA, 2014, pp. 31–38.
ista: 'Bauer U, Kerber M, Reininghaus J. 2014. Distributed computation of persistent
homology. Proceedings of the Workshop on Algorithm Engineering and Experiments.
ALENEX: Algorithm Engineering and Experiments, 31–38.'
mla: Bauer, Ulrich, et al. “Distributed Computation of Persistent Homology.” Proceedings
of the Workshop on Algorithm Engineering and Experiments, edited by Catherine McGeoch
and Ulrich Meyer, Society of Industrial and Applied Mathematics, 2014, pp. 31–38,
doi:10.1137/1.9781611973198.4.
short: U. Bauer, M. Kerber, J. Reininghaus, in:, C. McGeoch, U. Meyer (Eds.), Proceedings
of the Workshop on Algorithm Engineering and Experiments, Society of Industrial
and Applied Mathematics, 2014, pp. 31–38.
conference:
end_date: 2014-01-05
location: Portland, USA
name: 'ALENEX: Algorithm Engineering and Experiments'
start_date: 2014-01-05
date_created: 2018-12-11T11:55:23Z
date_published: 2014-01-01T00:00:00Z
date_updated: 2021-01-12T06:54:56Z
day: '01'
department:
- _id: HeEd
doi: 10.1137/1.9781611973198.4
ec_funded: 1
editor:
- first_name: Catherine
full_name: ' McGeoch, Catherine'
last_name: ' McGeoch'
- first_name: Ulrich
full_name: Meyer, Ulrich
last_name: Meyer
language:
- iso: eng
main_file_link:
- open_access: '1'
url: http://arxiv.org/abs/1310.0710
month: '01'
oa: 1
oa_version: Submitted Version
page: 31 - 38
project:
- _id: 255D761E-B435-11E9-9278-68D0E5697425
call_identifier: FP7
grant_number: '318493'
name: Topological Complex Systems
publication: Proceedings of the Workshop on Algorithm Engineering and Experiments
publication_status: published
publisher: Society of Industrial and Applied Mathematics
publist_id: '5008'
quality_controlled: '1'
scopus_import: 1
status: public
title: Distributed computation of persistent homology
type: conference
user_id: 4435EBFC-F248-11E8-B48F-1D18A9856A87
year: '2014'
...
---
_id: '2041'
abstract:
- lang: eng
text: The hippocampus mediates several higher brain functions, such as learning,
memory, and spatial coding. The input region of the hippocampus, the dentate gyrus,
plays a critical role in these processes. Several lines of evidence suggest that
the dentate gyrus acts as a preprocessor of incoming information, preparing it
for subsequent processing in CA3. For example, the dentate gyrus converts input
from the entorhinal cortex, where cells have multiple spatial fields, into the
spatially more specific place cell activity characteristic of the CA3 region.
Furthermore, the dentate gyrus is involved in pattern separation, transforming
relatively similar input patterns into substantially different output patterns.
Finally, the dentate gyrus produces a very sparse coding scheme in which only
a very small fraction of neurons are active at any one time.
article_number: 2p
author:
- first_name: Peter M
full_name: Jonas, Peter M
id: 353C1B58-F248-11E8-B48F-1D18A9856A87
last_name: Jonas
orcid: 0000-0001-5001-4804
- first_name: John
full_name: Lisman, John
last_name: Lisman
citation:
ama: Jonas PM, Lisman J. Structure, function and plasticity of hippocampal dentate
gyrus microcircuits. Frontiers in Neural Circuits. 2014;8. doi:10.3389/fncir.2014.00107
apa: Jonas, P. M., & Lisman, J. (2014). Structure, function and plasticity of
hippocampal dentate gyrus microcircuits. Frontiers in Neural Circuits.
Frontiers Research Foundation. https://doi.org/10.3389/fncir.2014.00107
chicago: Jonas, Peter M, and John Lisman. “Structure, Function and Plasticity of
Hippocampal Dentate Gyrus Microcircuits.” Frontiers in Neural Circuits.
Frontiers Research Foundation, 2014. https://doi.org/10.3389/fncir.2014.00107.
ieee: P. M. Jonas and J. Lisman, “Structure, function and plasticity of hippocampal
dentate gyrus microcircuits,” Frontiers in Neural Circuits, vol. 8. Frontiers
Research Foundation, 2014.
ista: Jonas PM, Lisman J. 2014. Structure, function and plasticity of hippocampal
dentate gyrus microcircuits. Frontiers in Neural Circuits. 8, 2p.
mla: Jonas, Peter M., and John Lisman. “Structure, Function and Plasticity of Hippocampal
Dentate Gyrus Microcircuits.” Frontiers in Neural Circuits, vol. 8, 2p,
Frontiers Research Foundation, 2014, doi:10.3389/fncir.2014.00107.
short: P.M. Jonas, J. Lisman, Frontiers in Neural Circuits 8 (2014).
date_created: 2018-12-11T11:55:22Z
date_published: 2014-09-10T00:00:00Z
date_updated: 2021-01-12T06:54:55Z
day: '10'
ddc:
- '570'
department:
- _id: PeJo
doi: 10.3389/fncir.2014.00107
file:
- access_level: open_access
checksum: 3ca57b164045523f876407e9f13a9fb8
content_type: application/pdf
creator: system
date_created: 2018-12-12T10:17:38Z
date_updated: 2020-07-14T12:45:26Z
file_id: '5294'
file_name: IST-2016-424-v1+1_fncir-08-00107.pdf
file_size: 201110
relation: main_file
file_date_updated: 2020-07-14T12:45:26Z
has_accepted_license: '1'
intvolume: ' 8'
language:
- iso: eng
month: '09'
oa: 1
oa_version: Published Version
publication: Frontiers in Neural Circuits
publication_status: published
publisher: Frontiers Research Foundation
publist_id: '5010'
pubrep_id: '424'
quality_controlled: '1'
scopus_import: 1
status: public
title: Structure, function and plasticity of hippocampal dentate gyrus microcircuits
tmp:
image: /images/cc_by.png
legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
short: CC BY (4.0)
type: journal_article
user_id: 4435EBFC-F248-11E8-B48F-1D18A9856A87
volume: 8
year: '2014'
...
---
_id: '2044'
abstract:
- lang: eng
text: We present a parallel algorithm for computing the persistent homology of a
filtered chain complex. Our approach differs from the commonly used reduction
algorithm by first computing persistence pairs within local chunks, then simplifying
the unpaired columns, and finally applying standard reduction on the simplified
matrix. The approach generalizes a technique by Günther et al., which uses discrete
Morse Theory to compute persistence; we derive the same worst-case complexity
bound in a more general context. The algorithm employs several practical optimization
techniques, which are of independent interest. Our sequential implementation of
the algorithm is competitive with state-of-the-art methods, and we further improve
the performance through parallel computation.
author:
- first_name: Ulrich
full_name: Bauer, Ulrich
id: 2ADD483A-F248-11E8-B48F-1D18A9856A87
last_name: Bauer
orcid: 0000-0002-9683-0724
- first_name: Michael
full_name: Kerber, Michael
last_name: Kerber
orcid: 0000-0002-8030-9299
- first_name: Jan
full_name: Reininghaus, Jan
id: 4505473A-F248-11E8-B48F-1D18A9856A87
last_name: Reininghaus
citation:
ama: 'Bauer U, Kerber M, Reininghaus J. Clear and Compress: Computing Persistent
Homology in Chunks. In: Bremer P-T, Hotz I, Pascucci V, Peikert R, eds. Topological
Methods in Data Analysis and Visualization III. Mathematics and Visualization.
Springer; 2014:103-117. doi:10.1007/978-3-319-04099-8_7'
apa: 'Bauer, U., Kerber, M., & Reininghaus, J. (2014). Clear and Compress: Computing
Persistent Homology in Chunks. In P.-T. Bremer, I. Hotz, V. Pascucci, & R.
Peikert (Eds.), Topological Methods in Data Analysis and Visualization III
(pp. 103–117). Springer. https://doi.org/10.1007/978-3-319-04099-8_7'
chicago: 'Bauer, Ulrich, Michael Kerber, and Jan Reininghaus. “Clear and Compress:
Computing Persistent Homology in Chunks.” In Topological Methods in Data Analysis
and Visualization III, edited by Peer-Timo Bremer, Ingrid Hotz, Valerio Pascucci,
and Ronald Peikert, 103–17. Mathematics and Visualization. Springer, 2014. https://doi.org/10.1007/978-3-319-04099-8_7.'
ieee: 'U. Bauer, M. Kerber, and J. Reininghaus, “Clear and Compress: Computing Persistent
Homology in Chunks,” in Topological Methods in Data Analysis and Visualization
III, P.-T. Bremer, I. Hotz, V. Pascucci, and R. Peikert, Eds. Springer, 2014,
pp. 103–117.'
ista: 'Bauer U, Kerber M, Reininghaus J. 2014.Clear and Compress: Computing Persistent
Homology in Chunks. In: Topological Methods in Data Analysis and Visualization
III. , 103–117.'
mla: 'Bauer, Ulrich, et al. “Clear and Compress: Computing Persistent Homology in
Chunks.” Topological Methods in Data Analysis and Visualization III, edited
by Peer-Timo Bremer et al., Springer, 2014, pp. 103–17, doi:10.1007/978-3-319-04099-8_7.'
short: U. Bauer, M. Kerber, J. Reininghaus, in:, P.-T. Bremer, I. Hotz, V. Pascucci,
R. Peikert (Eds.), Topological Methods in Data Analysis and Visualization III,
Springer, 2014, pp. 103–117.
date_created: 2018-12-11T11:55:23Z
date_published: 2014-03-19T00:00:00Z
date_updated: 2021-01-12T06:54:56Z
day: '19'
department:
- _id: HeEd
doi: 10.1007/978-3-319-04099-8_7
ec_funded: 1
editor:
- first_name: Peer-Timo
full_name: Bremer, Peer-Timo
last_name: Bremer
- first_name: Ingrid
full_name: Hotz, Ingrid
last_name: Hotz
- first_name: Valerio
full_name: Pascucci, Valerio
last_name: Pascucci
- first_name: Ronald
full_name: Peikert, Ronald
last_name: Peikert
language:
- iso: eng
main_file_link:
- open_access: '1'
url: http://arxiv.org/abs/1303.0477
month: '03'
oa: 1
oa_version: Submitted Version
page: 103 - 117
project:
- _id: 255D761E-B435-11E9-9278-68D0E5697425
call_identifier: FP7
grant_number: '318493'
name: Topological Complex Systems
publication: Topological Methods in Data Analysis and Visualization III
publication_status: published
publisher: Springer
publist_id: '5007'
quality_controlled: '1'
scopus_import: 1
series_title: Mathematics and Visualization
status: public
title: 'Clear and Compress: Computing Persistent Homology in Chunks'
type: book_chapter
user_id: 4435EBFC-F248-11E8-B48F-1D18A9856A87
year: '2014'
...
---
_id: '2040'
abstract:
- lang: eng
text: 'Development requires tissue growth as well as cell diversification. To address
how these processes are coordinated, we analyzed the development of molecularly
distinct domains of neural progenitors in the mouse and chick neural tube. We
show that during development, these domains undergo changes in size that do not
scale with changes in overall tissue size. Our data show that domain proportions
are first established by opposing morphogen gradients and subsequently controlled
by domain-specific regulation of differentiation rate but not differences in proliferation
rate. Regulation of differentiation rate is key to maintaining domain proportions
while accommodating both intra- and interspecies variations in size. Thus, the
sequential control of progenitor specification and differentiation elaborates
pattern without requiring that signaling gradients grow as tissues expand. '
article_number: '1254927'
author:
- first_name: Anna
full_name: Kicheva, Anna
last_name: Kicheva
- first_name: Mark Tobias
full_name: Bollenbach, Mark Tobias
id: 3E6DB97A-F248-11E8-B48F-1D18A9856A87
last_name: Bollenbach
orcid: 0000-0003-4398-476X
- first_name: Ana
full_name: Ribeiro, Ana
last_name: Ribeiro
- first_name: Helena
full_name: Pérez Valle, Helena
last_name: Pérez Valle
- first_name: Robin
full_name: Lovell Badge, Robin
last_name: Lovell Badge
- first_name: Vasso
full_name: Episkopou, Vasso
last_name: Episkopou
- first_name: James
full_name: Briscoe, James
last_name: Briscoe
citation:
ama: Kicheva A, Bollenbach MT, Ribeiro A, et al. Coordination of progenitor specification
and growth in mouse and chick spinal cord. Science. 2014;345(6204). doi:10.1126/science.1254927
apa: Kicheva, A., Bollenbach, M. T., Ribeiro, A., Pérez Valle, H., Lovell Badge,
R., Episkopou, V., & Briscoe, J. (2014). Coordination of progenitor specification
and growth in mouse and chick spinal cord. Science. American Association
for the Advancement of Science. https://doi.org/10.1126/science.1254927
chicago: Kicheva, Anna, Mark Tobias Bollenbach, Ana Ribeiro, Helena Pérez Valle,
Robin Lovell Badge, Vasso Episkopou, and James Briscoe. “Coordination of Progenitor
Specification and Growth in Mouse and Chick Spinal Cord.” Science. American
Association for the Advancement of Science, 2014. https://doi.org/10.1126/science.1254927.
ieee: A. Kicheva et al., “Coordination of progenitor specification and growth
in mouse and chick spinal cord,” Science, vol. 345, no. 6204. American
Association for the Advancement of Science, 2014.
ista: Kicheva A, Bollenbach MT, Ribeiro A, Pérez Valle H, Lovell Badge R, Episkopou
V, Briscoe J. 2014. Coordination of progenitor specification and growth in mouse
and chick spinal cord. Science. 345(6204), 1254927.
mla: Kicheva, Anna, et al. “Coordination of Progenitor Specification and Growth
in Mouse and Chick Spinal Cord.” Science, vol. 345, no. 6204, 1254927,
American Association for the Advancement of Science, 2014, doi:10.1126/science.1254927.
short: A. Kicheva, M.T. Bollenbach, A. Ribeiro, H. Pérez Valle, R. Lovell Badge,
V. Episkopou, J. Briscoe, Science 345 (2014).
date_created: 2018-12-11T11:55:22Z
date_published: 2014-09-26T00:00:00Z
date_updated: 2021-01-12T06:54:55Z
day: '26'
department:
- _id: ToBo
doi: 10.1126/science.1254927
intvolume: ' 345'
issue: '6204'
language:
- iso: eng
main_file_link:
- open_access: '1'
url: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4228193/
month: '09'
oa: 1
oa_version: Submitted Version
publication: Science
publication_status: published
publisher: American Association for the Advancement of Science
publist_id: '5011'
quality_controlled: '1'
scopus_import: 1
status: public
title: Coordination of progenitor specification and growth in mouse and chick spinal
cord
type: journal_article
user_id: 4435EBFC-F248-11E8-B48F-1D18A9856A87
volume: 345
year: '2014'
...
---
_id: '2047'
abstract:
- lang: eng
text: Following the publication of an attack on genome-wide association studies
(GWAS) data proposed by Homer et al., considerable attention has been given to
developing methods for releasing GWAS data in a privacy-preserving way. Here,
we develop an end-to-end differentially private method for solving regression
problems with convex penalty functions and selecting the penalty parameters by
cross-validation. In particular, we focus on penalized logistic regression with
elastic-net regularization, a method widely used to in GWAS analyses to identify
disease-causing genes. We show how a differentially private procedure for penalized
logistic regression with elastic-net regularization can be applied to the analysis
of GWAS data and evaluate our method’s performance.
acknowledgement: This research was partially supported by BCS- 0941518 to the Department
of Statistics at Carnegie Mellon University.
alternative_title:
- LNCS
author:
- first_name: Fei
full_name: Yu, Fei
last_name: Yu
- first_name: Michal
full_name: Rybar, Michal
id: 2B3E3DE8-F248-11E8-B48F-1D18A9856A87
last_name: Rybar
- first_name: Caroline
full_name: Uhler, Caroline
id: 49ADD78E-F248-11E8-B48F-1D18A9856A87
last_name: Uhler
orcid: 0000-0002-7008-0216
- first_name: Stephen
full_name: Fienberg, Stephen
last_name: Fienberg
citation:
ama: 'Yu F, Rybar M, Uhler C, Fienberg S. Differentially-private logistic regression
for detecting multiple-SNP association in GWAS databases. In: Domingo Ferrer J,
ed. Lecture Notes in Computer Science (Including Subseries Lecture Notes in
Artificial Intelligence and Lecture Notes in Bioinformatics). Vol 8744. Springer;
2014:170-184. doi:10.1007/978-3-319-11257-2_14'
apa: 'Yu, F., Rybar, M., Uhler, C., & Fienberg, S. (2014). Differentially-private
logistic regression for detecting multiple-SNP association in GWAS databases.
In J. Domingo Ferrer (Ed.), Lecture Notes in Computer Science (including subseries
Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics)
(Vol. 8744, pp. 170–184). Ibiza, Spain: Springer. https://doi.org/10.1007/978-3-319-11257-2_14'
chicago: Yu, Fei, Michal Rybar, Caroline Uhler, and Stephen Fienberg. “Differentially-Private
Logistic Regression for Detecting Multiple-SNP Association in GWAS Databases.”
In Lecture Notes in Computer Science (Including Subseries Lecture Notes in
Artificial Intelligence and Lecture Notes in Bioinformatics), edited by Josep
Domingo Ferrer, 8744:170–84. Springer, 2014. https://doi.org/10.1007/978-3-319-11257-2_14.
ieee: F. Yu, M. Rybar, C. Uhler, and S. Fienberg, “Differentially-private logistic
regression for detecting multiple-SNP association in GWAS databases,” in Lecture
Notes in Computer Science (including subseries Lecture Notes in Artificial Intelligence
and Lecture Notes in Bioinformatics), Ibiza, Spain, 2014, vol. 8744, pp. 170–184.
ista: 'Yu F, Rybar M, Uhler C, Fienberg S. 2014. Differentially-private logistic
regression for detecting multiple-SNP association in GWAS databases. Lecture Notes
in Computer Science (including subseries Lecture Notes in Artificial Intelligence
and Lecture Notes in Bioinformatics). PSD: Privacy in Statistical Databases, LNCS,
vol. 8744, 170–184.'
mla: Yu, Fei, et al. “Differentially-Private Logistic Regression for Detecting Multiple-SNP
Association in GWAS Databases.” Lecture Notes in Computer Science (Including
Subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics),
edited by Josep Domingo Ferrer, vol. 8744, Springer, 2014, pp. 170–84, doi:10.1007/978-3-319-11257-2_14.
short: F. Yu, M. Rybar, C. Uhler, S. Fienberg, in:, J. Domingo Ferrer (Ed.), Lecture
Notes in Computer Science (Including Subseries Lecture Notes in Artificial Intelligence
and Lecture Notes in Bioinformatics), Springer, 2014, pp. 170–184.
conference:
end_date: 2014-09-19
location: Ibiza, Spain
name: 'PSD: Privacy in Statistical Databases'
start_date: 2014-09-17
date_created: 2018-12-11T11:55:24Z
date_published: 2014-01-01T00:00:00Z
date_updated: 2021-01-12T06:54:57Z
day: '01'
department:
- _id: KrPi
- _id: CaUh
doi: 10.1007/978-3-319-11257-2_14
editor:
- first_name: Josep
full_name: Domingo Ferrer, Josep
last_name: Domingo Ferrer
external_id:
arxiv:
- '1407.8067'
intvolume: ' 8744'
language:
- iso: eng
main_file_link:
- open_access: '1'
url: http://arxiv.org/abs/1407.8067
month: '01'
oa: 1
oa_version: Submitted Version
page: 170 - 184
project:
- _id: 25636330-B435-11E9-9278-68D0E5697425
grant_number: 11-NSF-1070
name: ROOTS Genome-wide Analysis of Root Traits
publication: Lecture Notes in Computer Science (including subseries Lecture Notes
in Artificial Intelligence and Lecture Notes in Bioinformatics)
publication_status: published
publisher: Springer
publist_id: '5004'
quality_controlled: '1'
scopus_import: 1
status: public
title: Differentially-private logistic regression for detecting multiple-SNP association
in GWAS databases
type: conference
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 8744
year: '2014'
...
---
_id: '2053'
abstract:
- lang: eng
text: In contrast to the usual understanding of probabilistic systems as stochastic
processes, recently these systems have also been regarded as transformers of probabilities.
In this paper, we give a natural definition of strong bisimulation for probabilistic
systems corresponding to this view that treats probability distributions as first-class
citizens. Our definition applies in the same way to discrete systems as well as
to systems with uncountable state and action spaces. Several examples demonstrate
that our definition refines the understanding of behavioural equivalences of probabilistic
systems. In particular, it solves a longstanding open problem concerning the representation
of memoryless continuous time by memoryfull continuous time. Finally, we give
algorithms for computing this bisimulation not only for finite but also for classes
of uncountably infinite systems.
acknowledgement: This work is supported by the EU 7th Framework Programme under grant
agreements 295261 (MEALS) and 318490 (SENSATION), Czech Science Foundation under
grant agreement P202/12/G061, the DFG Transregional Collaborative Research Centre
SFB/TR 14 AVACS, and by the CAS/SAFEA International Partnership Program for Creative
Research Teams.
alternative_title:
- LNCS
author:
- first_name: Holger
full_name: Hermanns, Holger
last_name: Hermanns
- first_name: Jan
full_name: Krčál, Jan
last_name: Krčál
- first_name: Jan
full_name: Kretinsky, Jan
id: 44CEF464-F248-11E8-B48F-1D18A9856A87
last_name: Kretinsky
orcid: 0000-0002-8122-2881
citation:
ama: 'Hermanns H, Krčál J, Kretinsky J. Probabilistic bisimulation: Naturally on
distributions. In: Baldan P, Gorla D, eds. Lecture Notes in Computer Science
(Including Subseries Lecture Notes in Artificial Intelligence and Lecture Notes
in Bioinformatics). Vol 8704. Schloss Dagstuhl - Leibniz-Zentrum für Informatik;
2014:249-265. doi:10.1007/978-3-662-44584-6_18'
apa: 'Hermanns, H., Krčál, J., & Kretinsky, J. (2014). Probabilistic bisimulation:
Naturally on distributions. In P. Baldan & D. Gorla (Eds.), Lecture Notes
in Computer Science (including subseries Lecture Notes in Artificial Intelligence
and Lecture Notes in Bioinformatics) (Vol. 8704, pp. 249–265). Rome, Italy:
Schloss Dagstuhl - Leibniz-Zentrum für Informatik. https://doi.org/10.1007/978-3-662-44584-6_18'
chicago: 'Hermanns, Holger, Jan Krčál, and Jan Kretinsky. “Probabilistic Bisimulation:
Naturally on Distributions.” In Lecture Notes in Computer Science (Including
Subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics),
edited by Paolo Baldan and Daniele Gorla, 8704:249–65. Schloss Dagstuhl - Leibniz-Zentrum
für Informatik, 2014. https://doi.org/10.1007/978-3-662-44584-6_18.'
ieee: 'H. Hermanns, J. Krčál, and J. Kretinsky, “Probabilistic bisimulation: Naturally
on distributions,” in Lecture Notes in Computer Science (including subseries
Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics),
Rome, Italy, 2014, vol. 8704, pp. 249–265.'
ista: 'Hermanns H, Krčál J, Kretinsky J. 2014. Probabilistic bisimulation: Naturally
on distributions. Lecture Notes in Computer Science (including subseries Lecture
Notes in Artificial Intelligence and Lecture Notes in Bioinformatics). CONCUR:
Concurrency Theory, LNCS, vol. 8704, 249–265.'
mla: 'Hermanns, Holger, et al. “Probabilistic Bisimulation: Naturally on Distributions.”
Lecture Notes in Computer Science (Including Subseries Lecture Notes in Artificial
Intelligence and Lecture Notes in Bioinformatics), edited by Paolo Baldan
and Daniele Gorla, vol. 8704, Schloss Dagstuhl - Leibniz-Zentrum für Informatik,
2014, pp. 249–65, doi:10.1007/978-3-662-44584-6_18.'
short: H. Hermanns, J. Krčál, J. Kretinsky, in:, P. Baldan, D. Gorla (Eds.), Lecture
Notes in Computer Science (Including Subseries Lecture Notes in Artificial Intelligence
and Lecture Notes in Bioinformatics), Schloss Dagstuhl - Leibniz-Zentrum für Informatik,
2014, pp. 249–265.
conference:
end_date: 2014-09-05
location: Rome, Italy
name: 'CONCUR: Concurrency Theory'
start_date: 2014-09-02
date_created: 2018-12-11T11:55:27Z
date_published: 2014-09-01T00:00:00Z
date_updated: 2021-01-12T06:55:00Z
day: '01'
department:
- _id: ToHe
- _id: KrCh
doi: 10.1007/978-3-662-44584-6_18
ec_funded: 1
editor:
- first_name: Paolo
full_name: Baldan, Paolo
last_name: Baldan
- first_name: Daniele
full_name: Gorla, Daniele
last_name: Gorla
intvolume: ' 8704'
language:
- iso: eng
main_file_link:
- open_access: '1'
url: http://arxiv.org/abs/1404.5084
month: '09'
oa: 1
oa_version: Submitted Version
page: 249 - 265
project:
- _id: 25EE3708-B435-11E9-9278-68D0E5697425
call_identifier: FP7
grant_number: '267989'
name: Quantitative Reactive Modeling
- _id: 25F5A88A-B435-11E9-9278-68D0E5697425
call_identifier: FWF
grant_number: S11402-N23
name: Moderne Concurrency Paradigms
publication: Lecture Notes in Computer Science (including subseries Lecture Notes
in Artificial Intelligence and Lecture Notes in Bioinformatics)
publication_status: published
publisher: Schloss Dagstuhl - Leibniz-Zentrum für Informatik
publist_id: '4993'
status: public
title: 'Probabilistic bisimulation: Naturally on distributions'
type: conference
user_id: 4435EBFC-F248-11E8-B48F-1D18A9856A87
volume: 8704
year: '2014'
...
---
_id: '2052'
abstract:
- lang: eng
text: A standard technique for solving the parameterized model checking problem
is to reduce it to the classic model checking problem of finitely many finite-state
systems. This work considers some of the theoretical power and limitations of
this technique. We focus on concurrent systems in which processes communicate
via pairwise rendezvous, as well as the special cases of disjunctive guards and
token passing; specifications are expressed in indexed temporal logic without
the next operator; and the underlying network topologies are generated by suitable
Monadic Second Order Logic formulas and graph operations. First, we settle the
exact computational complexity of the parameterized model checking problem for
some of our concurrent systems, and establish new decidability results for others.
Second, we consider the cases that model checking the parameterized system can
be reduced to model checking some fixed number of processes, the number is known
as a cutoff. We provide many cases for when such cutoffs can be computed, establish
lower bounds on the size of such cutoffs, and identify cases where no cutoff exists.
Third, we consider cases for which the parameterized system is equivalent to a
single finite-state system (more precisely a Büchi word automaton), and establish
tight bounds on the sizes of such automata.
acknowledgement: The second, third, fourth and fifth authors were supported by the
Austrian National Research Network S11403-N23 (RiSE) of the Austrian Science Fund
(FWF) and by the Vienna Science and Technology Fund (WWTF) through grants PROSEED,
ICT12-059, and VRG11-005.
alternative_title:
- LNCS
author:
- first_name: Benjamin
full_name: Aminof, Benjamin
id: 4A55BD00-F248-11E8-B48F-1D18A9856A87
last_name: Aminof
- first_name: Tomer
full_name: Kotek, Tomer
last_name: Kotek
- first_name: Sacha
full_name: Rubin, Sacha
last_name: Rubin
- first_name: Francesco
full_name: Spegni, Francesco
last_name: Spegni
- first_name: Helmut
full_name: Veith, Helmut
last_name: Veith
citation:
ama: 'Aminof B, Kotek T, Rubin S, Spegni F, Veith H. Parameterized model checking
of rendezvous systems. In: Baldan P, Gorla D, eds. Lecture Notes in Computer
Science (Including Subseries Lecture Notes in Artificial Intelligence and Lecture
Notes in Bioinformatics). Vol 8704. Schloss Dagstuhl - Leibniz-Zentrum für
Informatik; 2014:109-124. doi:10.1007/978-3-662-44584-6_9'
apa: 'Aminof, B., Kotek, T., Rubin, S., Spegni, F., & Veith, H. (2014). Parameterized
model checking of rendezvous systems. In P. Baldan & D. Gorla (Eds.), Lecture
Notes in Computer Science (including subseries Lecture Notes in Artificial Intelligence
and Lecture Notes in Bioinformatics) (Vol. 8704, pp. 109–124). Rome, Italy:
Schloss Dagstuhl - Leibniz-Zentrum für Informatik. https://doi.org/10.1007/978-3-662-44584-6_9'
chicago: Aminof, Benjamin, Tomer Kotek, Sacha Rubin, Francesco Spegni, and Helmut
Veith. “Parameterized Model Checking of Rendezvous Systems.” In Lecture Notes
in Computer Science (Including Subseries Lecture Notes in Artificial Intelligence
and Lecture Notes in Bioinformatics), edited by Paolo Baldan and Daniele Gorla,
8704:109–24. Schloss Dagstuhl - Leibniz-Zentrum für Informatik, 2014. https://doi.org/10.1007/978-3-662-44584-6_9.
ieee: B. Aminof, T. Kotek, S. Rubin, F. Spegni, and H. Veith, “Parameterized model
checking of rendezvous systems,” in Lecture Notes in Computer Science (including
subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics),
Rome, Italy, 2014, vol. 8704, pp. 109–124.
ista: 'Aminof B, Kotek T, Rubin S, Spegni F, Veith H. 2014. Parameterized model
checking of rendezvous systems. Lecture Notes in Computer Science (including subseries
Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics).
CONCUR: Concurrency Theory, LNCS, vol. 8704, 109–124.'
mla: Aminof, Benjamin, et al. “Parameterized Model Checking of Rendezvous Systems.”
Lecture Notes in Computer Science (Including Subseries Lecture Notes in Artificial
Intelligence and Lecture Notes in Bioinformatics), edited by Paolo Baldan
and Daniele Gorla, vol. 8704, Schloss Dagstuhl - Leibniz-Zentrum für Informatik,
2014, pp. 109–24, doi:10.1007/978-3-662-44584-6_9.
short: B. Aminof, T. Kotek, S. Rubin, F. Spegni, H. Veith, in:, P. Baldan, D. Gorla
(Eds.), Lecture Notes in Computer Science (Including Subseries Lecture Notes in
Artificial Intelligence and Lecture Notes in Bioinformatics), Schloss Dagstuhl
- Leibniz-Zentrum für Informatik, 2014, pp. 109–124.
conference:
end_date: 2014-09-05
location: Rome, Italy
name: 'CONCUR: Concurrency Theory'
start_date: 2014-09-02
date_created: 2018-12-11T11:55:26Z
date_published: 2014-09-01T00:00:00Z
date_updated: 2021-01-12T06:54:59Z
day: '01'
department:
- _id: KrCh
doi: 10.1007/978-3-662-44584-6_9
editor:
- first_name: Paolo
full_name: Baldan, Paolo
last_name: Baldan
- first_name: Daniele
full_name: Gorla, Daniele
last_name: Gorla
intvolume: ' 8704'
language:
- iso: eng
month: '09'
oa_version: None
page: 109 - 124
publication: Lecture Notes in Computer Science (including subseries Lecture Notes
in Artificial Intelligence and Lecture Notes in Bioinformatics)
publication_status: published
publisher: Schloss Dagstuhl - Leibniz-Zentrum für Informatik
publist_id: '4994'
quality_controlled: '1'
status: public
title: Parameterized model checking of rendezvous systems
type: conference
user_id: 4435EBFC-F248-11E8-B48F-1D18A9856A87
volume: 8704
year: '2014'
...
---
_id: '2046'
abstract:
- lang: eng
text: 'We introduce policy-based signatures (PBS), where a signer can only sign
messages conforming to some authority-specified policy. The main requirements
are unforgeability and privacy, the latter meaning that signatures not reveal
the policy. PBS offers value along two fronts: (1) On the practical side, they
allow a corporation to control what messages its employees can sign under the
corporate key. (2) On the theoretical side, they unify existing work, capturing
other forms of signatures as special cases or allowing them to be easily built.
Our work focuses on definitions of PBS, proofs that this challenging primitive
is realizable for arbitrary policies, efficient constructions for specific policies,
and a few representative applications.'
acknowledgement: Part of his work was done while at Bristol University, supported
by EPSRC grant EP/H043454/1.
alternative_title:
- LNCS
author:
- first_name: Mihir
full_name: Bellare, Mihir
last_name: Bellare
- first_name: Georg
full_name: Fuchsbauer, Georg
id: 46B4C3EE-F248-11E8-B48F-1D18A9856A87
last_name: Fuchsbauer
citation:
ama: 'Bellare M, Fuchsbauer G. Policy-based signatures. In: Krawczyk H, ed. Lecture
Notes in Computer Science (Including Subseries Lecture Notes in Artificial Intelligence
and Lecture Notes in Bioinformatics). Vol 8383. Springer; 2014:520-537. doi:10.1007/978-3-642-54631-0_30'
apa: 'Bellare, M., & Fuchsbauer, G. (2014). Policy-based signatures. In H. Krawczyk
(Ed.), Lecture Notes in Computer Science (including subseries Lecture Notes
in Artificial Intelligence and Lecture Notes in Bioinformatics) (Vol. 8383,
pp. 520–537). Buenos Aires, Argentina: Springer. https://doi.org/10.1007/978-3-642-54631-0_30'
chicago: Bellare, Mihir, and Georg Fuchsbauer. “Policy-Based Signatures.” In Lecture
Notes in Computer Science (Including Subseries Lecture Notes in Artificial Intelligence
and Lecture Notes in Bioinformatics), edited by Hugo Krawczyk, 8383:520–37.
Springer, 2014. https://doi.org/10.1007/978-3-642-54631-0_30.
ieee: M. Bellare and G. Fuchsbauer, “Policy-based signatures,” in Lecture Notes
in Computer Science (including subseries Lecture Notes in Artificial Intelligence
and Lecture Notes in Bioinformatics), Buenos Aires, Argentina, 2014, vol.
8383, pp. 520–537.
ista: 'Bellare M, Fuchsbauer G. 2014. Policy-based signatures. Lecture Notes in
Computer Science (including subseries Lecture Notes in Artificial Intelligence
and Lecture Notes in Bioinformatics). PKC: Public Key Crypography, LNCS, vol.
8383, 520–537.'
mla: Bellare, Mihir, and Georg Fuchsbauer. “Policy-Based Signatures.” Lecture
Notes in Computer Science (Including Subseries Lecture Notes in Artificial Intelligence
and Lecture Notes in Bioinformatics), edited by Hugo Krawczyk, vol. 8383,
Springer, 2014, pp. 520–37, doi:10.1007/978-3-642-54631-0_30.
short: M. Bellare, G. Fuchsbauer, in:, H. Krawczyk (Ed.), Lecture Notes in Computer
Science (Including Subseries Lecture Notes in Artificial Intelligence and Lecture
Notes in Bioinformatics), Springer, 2014, pp. 520–537.
conference:
end_date: 2014-05-28
location: Buenos Aires, Argentina
name: 'PKC: Public Key Crypography'
start_date: 2014-05-26
date_created: 2018-12-11T11:55:24Z
date_published: 2014-01-01T00:00:00Z
date_updated: 2021-01-12T06:54:57Z
day: '01'
department:
- _id: KrPi
doi: 10.1007/978-3-642-54631-0_30
ec_funded: 1
editor:
- first_name: Hugo
full_name: Krawczyk, Hugo
last_name: Krawczyk
intvolume: ' 8383'
language:
- iso: eng
main_file_link:
- open_access: '1'
url: https://eprint.iacr.org/2013/413
month: '01'
oa: 1
oa_version: Submitted Version
page: 520 - 537
project:
- _id: 258C570E-B435-11E9-9278-68D0E5697425
call_identifier: FP7
grant_number: '259668'
name: Provable Security for Physical Cryptography
publication: Lecture Notes in Computer Science (including subseries Lecture Notes
in Artificial Intelligence and Lecture Notes in Bioinformatics)
publication_status: published
publisher: Springer
publist_id: '5005'
quality_controlled: '1'
scopus_import: 1
status: public
title: Policy-based signatures
type: conference
user_id: 4435EBFC-F248-11E8-B48F-1D18A9856A87
volume: 8383
year: '2014'
...
---
_id: '2050'
abstract:
- lang: eng
text: The flow instability and further transition to turbulence in a toroidal pipe
(torus) with curvature ratio (tube-to-coiling diameter) 0.049 is investigated
experimentally. The flow inside the toroidal pipe is driven by a steel sphere
fitted to the inner pipe diameter. The sphere is moved with constant azimuthal
velocity from outside the torus by a moving magnet. The experiment is designed
to investigate curved pipe flow by optical measurement techniques. Using stereoscopic
particle image velocimetry, laser Doppler velocimetry and pressure drop measurements,
the flow is measured for Reynolds numbers ranging from 1000 to 15 000. Time- and
space-resolved velocity fields are obtained and analysed. The steady axisymmetric
basic flow is strongly influenced by centrifugal effects. On an increase of the
Reynolds number we find a sequence of bifurcations. For Re=4075±2% a supercritical
bifurcation to an oscillatory flow is found in which waves travel in the streamwise
direction with a phase velocity slightly faster than the mean flow. The oscillatory
flow is superseded by a presumably quasi-periodic flow at a further increase of
the Reynolds number before turbulence sets in. The results are found to be compatible,
in general, with earlier experimental and numerical investigations on transition
to turbulence in helical and curved pipes. However, important aspects of the bifurcation
scenario differ considerably.
article_processing_charge: No
author:
- first_name: Jakob
full_name: Kühnen, Jakob
id: 3A47AE32-F248-11E8-B48F-1D18A9856A87
last_name: Kühnen
orcid: 0000-0003-4312-0179
- first_name: Markus
full_name: Holzner, Markus
last_name: Holzner
- first_name: Björn
full_name: Hof, Björn
id: 3A374330-F248-11E8-B48F-1D18A9856A87
last_name: Hof
orcid: 0000-0003-2057-2754
- first_name: Hendrik
full_name: Kuhlmann, Hendrik
last_name: Kuhlmann
citation:
ama: Kühnen J, Holzner M, Hof B, Kuhlmann H. Experimental investigation of transitional
flow in a toroidal pipe. Journal of Fluid Mechanics. 2014;738:463-491.
doi:10.1017/jfm.2013.603
apa: Kühnen, J., Holzner, M., Hof, B., & Kuhlmann, H. (2014). Experimental investigation
of transitional flow in a toroidal pipe. Journal of Fluid Mechanics. Cambridge
University Press. https://doi.org/10.1017/jfm.2013.603
chicago: Kühnen, Jakob, Markus Holzner, Björn Hof, and Hendrik Kuhlmann. “Experimental
Investigation of Transitional Flow in a Toroidal Pipe.” Journal of Fluid Mechanics.
Cambridge University Press, 2014. https://doi.org/10.1017/jfm.2013.603.
ieee: J. Kühnen, M. Holzner, B. Hof, and H. Kuhlmann, “Experimental investigation
of transitional flow in a toroidal pipe,” Journal of Fluid Mechanics, vol.
738. Cambridge University Press, pp. 463–491, 2014.
ista: Kühnen J, Holzner M, Hof B, Kuhlmann H. 2014. Experimental investigation of
transitional flow in a toroidal pipe. Journal of Fluid Mechanics. 738, 463–491.
mla: Kühnen, Jakob, et al. “Experimental Investigation of Transitional Flow in a
Toroidal Pipe.” Journal of Fluid Mechanics, vol. 738, Cambridge University
Press, 2014, pp. 463–91, doi:10.1017/jfm.2013.603.
short: J. Kühnen, M. Holzner, B. Hof, H. Kuhlmann, Journal of Fluid Mechanics 738
(2014) 463–491.
date_created: 2018-12-11T11:55:25Z
date_published: 2014-01-10T00:00:00Z
date_updated: 2021-01-12T06:54:59Z
day: '10'
department:
- _id: BjHo
doi: 10.1017/jfm.2013.603
external_id:
arxiv:
- '1508.06546'
intvolume: ' 738'
language:
- iso: eng
main_file_link:
- open_access: '1'
url: https://arxiv.org/abs/1508.06546
month: '01'
oa: 1
oa_version: Submitted Version
page: 463 - 491
publication: Journal of Fluid Mechanics
publication_status: published
publisher: Cambridge University Press
publist_id: '5001'
quality_controlled: '1'
scopus_import: 1
status: public
title: Experimental investigation of transitional flow in a toroidal pipe
type: journal_article
user_id: 3E5EF7F0-F248-11E8-B48F-1D18A9856A87
volume: 738
year: '2014'
...
---
_id: '2051'
abstract:
- lang: eng
text: We show that the usual score function for conditional Markov networks can
be written as the expectation over the scores of their spanning trees. We also
show that a small random sample of these output trees can attain a significant
fraction of the margin obtained by the complete graph and we provide conditions
under which we can perform tractable inference. The experimental results confirm
that practical learning is scalable to realistic datasets using this approach.
author:
- first_name: Mario
full_name: Marchand, Mario
last_name: Marchand
- first_name: Su
full_name: Hongyu, Su
last_name: Hongyu
- first_name: Emilie
full_name: Emilie Morvant
id: 4BAC2A72-F248-11E8-B48F-1D18A9856A87
last_name: Morvant
orcid: 0000-0002-8301-7240
- first_name: Juho
full_name: Rousu, Juho
last_name: Rousu
- first_name: John
full_name: Shawe-Taylor, John
last_name: Shawe Taylor
citation:
ama: 'Marchand M, Hongyu S, Morvant E, Rousu J, Shawe Taylor J. Multilabel structured
output learning with random spanning trees of max-margin Markov networks. In:
Neural Information Processing Systems; 2014.'
apa: 'Marchand, M., Hongyu, S., Morvant, E., Rousu, J., & Shawe Taylor, J. (2014).
Multilabel structured output learning with random spanning trees of max-margin
Markov networks. Presented at the NIPS: Neural Information Processing Systems,
Neural Information Processing Systems.'
chicago: Marchand, Mario, Su Hongyu, Emilie Morvant, Juho Rousu, and John Shawe
Taylor. “Multilabel Structured Output Learning with Random Spanning Trees of Max-Margin
Markov Networks.” Neural Information Processing Systems, 2014.
ieee: 'M. Marchand, S. Hongyu, E. Morvant, J. Rousu, and J. Shawe Taylor, “Multilabel
structured output learning with random spanning trees of max-margin Markov networks,”
presented at the NIPS: Neural Information Processing Systems, 2014.'
ista: 'Marchand M, Hongyu S, Morvant E, Rousu J, Shawe Taylor J. 2014. Multilabel
structured output learning with random spanning trees of max-margin Markov networks.
NIPS: Neural Information Processing Systems.'
mla: Marchand, Mario, et al. Multilabel Structured Output Learning with Random
Spanning Trees of Max-Margin Markov Networks. Neural Information Processing
Systems, 2014.
short: M. Marchand, S. Hongyu, E. Morvant, J. Rousu, J. Shawe Taylor, in:, Neural
Information Processing Systems, 2014.
conference:
name: 'NIPS: Neural Information Processing Systems'
date_created: 2018-12-11T11:55:26Z
date_published: 2014-01-01T00:00:00Z
date_updated: 2021-01-12T06:54:59Z
day: '01'
extern: 1
main_file_link:
- open_access: '1'
url: https://hal.archives-ouvertes.fr/hal-01065586
month: '01'
oa: 1
publication_status: published
publisher: Neural Information Processing Systems
publist_id: '4996'
quality_controlled: 0
status: public
title: Multilabel structured output learning with random spanning trees of max-margin
Markov networks
type: conference
year: '2014'
...
---
_id: '2059'
abstract:
- lang: eng
text: Plant embryogenesis is regulated by differential distribution of the plant
hormone auxin. However, the cells establishing these gradients during microspore
embryogenesis remain to be identified. For the first time, we describe, using
the DR5 or DR5rev reporter gene systems, the GFP- and GUS-based auxin biosensors
to monitor auxin during Brassica napus androgenesis at cellular resolution in
the initial stages. Our study provides evidence that the distribution of auxin
changes during embryo development and depends on the temperature-inducible in
vitro culture conditions. For this, microspores (mcs) were induced to embryogenesis
by heat treatment and then subjected to genetic modification via Agrobacterium
tumefaciens. The duration of high temperature treatment had a significant influence
on auxin distribution in isolated and in vitro-cultured microspores and on microspore-derived
embryo development. In the “mild” heat-treated (1 day at 32 °C) mcs, auxin localized
in a polar way already at the uni-nucleate microspore, which was critical for
the initiation of embryos with suspensor-like structure. Assuming a mean mcs radius
of 20 μm, endogenous auxin content in a single cell corresponded to concentration
of 1.01 μM. In mcs subjected to a prolonged heat (5 days at 32 °C), although auxin
concentration increased dozen times, auxin polarization was set up at a few-celled
pro-embryos without suspensor. Those embryos were enclosed in the outer wall called
the exine. The exine rupture was accompanied by the auxin gradient polarization.
Relative quantitative estimation of auxin, using time-lapse imaging, revealed
that primordia possess up to 1.3-fold higher amounts than those found in the root
apices of transgenic MDEs in the presence of exogenous auxin. Our results show,
for the first time, which concentration of endogenous auxin coincides with the
first cell division and how the high temperature interplays with auxin, by what
affects delay early establishing microspore polarity. Moreover, we present how
the local auxin accumulation demonstrates the apical–basal axis formation of the
androgenic embryo and directs the axiality of the adult haploid plant.
acknowledgement: The research was supported by the IPP PAS-IPGB SAS bilateral project
(“Molecular analysis of auxin distribution in oilseed androgenic embryos”), IPP
PAS-FWO VIB bilateral project (“Auxin as signaling molecule in doubled haploid production
of rape (B. napus var. oleifera)”), individual national research project 2011/01/D/NZ9/02547,
and VEGA 2-0090-14.
author:
- first_name: Ewa
full_name: Dubas, Ewa
last_name: Dubas
- first_name: Jana
full_name: Moravčíková, Jana
last_name: Moravčíková
- first_name: Jana
full_name: Libantová, Jana
last_name: Libantová
- first_name: Ildikó
full_name: Matušíková, Ildikó
last_name: Matušíková
- first_name: Eva
full_name: Benková, Eva
id: 38F4F166-F248-11E8-B48F-1D18A9856A87
last_name: Benková
orcid: 0000-0002-8510-9739
- first_name: Iwona
full_name: Zur, Iwona
last_name: Zur
- first_name: Monika
full_name: Krzewska, Monika
last_name: Krzewska
citation:
ama: Dubas E, Moravčíková J, Libantová J, et al. The influence of heat stress on
auxin distribution in transgenic B napus microspores and microspore derived embryos.
Protoplasma. 2014;251(5):1077-1087. doi:10.1007/s00709-014-0616-1
apa: Dubas, E., Moravčíková, J., Libantová, J., Matušíková, I., Benková, E., Zur,
I., & Krzewska, M. (2014). The influence of heat stress on auxin distribution
in transgenic B napus microspores and microspore derived embryos. Protoplasma.
Springer. https://doi.org/10.1007/s00709-014-0616-1
chicago: Dubas, Ewa, Jana Moravčíková, Jana Libantová, Ildikó Matušíková, Eva Benková,
Iwona Zur, and Monika Krzewska. “The Influence of Heat Stress on Auxin Distribution
in Transgenic B Napus Microspores and Microspore Derived Embryos.” Protoplasma.
Springer, 2014. https://doi.org/10.1007/s00709-014-0616-1.
ieee: E. Dubas et al., “The influence of heat stress on auxin distribution
in transgenic B napus microspores and microspore derived embryos,” Protoplasma,
vol. 251, no. 5. Springer, pp. 1077–1087, 2014.
ista: Dubas E, Moravčíková J, Libantová J, Matušíková I, Benková E, Zur I, Krzewska
M. 2014. The influence of heat stress on auxin distribution in transgenic B napus
microspores and microspore derived embryos. Protoplasma. 251(5), 1077–1087.
mla: Dubas, Ewa, et al. “The Influence of Heat Stress on Auxin Distribution in Transgenic
B Napus Microspores and Microspore Derived Embryos.” Protoplasma, vol.
251, no. 5, Springer, 2014, pp. 1077–87, doi:10.1007/s00709-014-0616-1.
short: E. Dubas, J. Moravčíková, J. Libantová, I. Matušíková, E. Benková, I. Zur,
M. Krzewska, Protoplasma 251 (2014) 1077–1087.
date_created: 2018-12-11T11:55:29Z
date_published: 2014-02-20T00:00:00Z
date_updated: 2021-01-12T06:55:02Z
day: '20'
ddc:
- '580'
department:
- _id: EvBe
doi: 10.1007/s00709-014-0616-1
file:
- access_level: open_access
checksum: d570a6073765118fc0bb83c31d96fa53
content_type: application/pdf
creator: system
date_created: 2018-12-12T10:18:31Z
date_updated: 2020-07-14T12:45:27Z
file_id: '5353'
file_name: IST-2015-394-v1+1_s00709-014-0616-1.pdf
file_size: 6377990
relation: main_file
file_date_updated: 2020-07-14T12:45:27Z
has_accepted_license: '1'
intvolume: ' 251'
issue: '5'
language:
- iso: eng
month: '02'
oa: 1
oa_version: Published Version
page: 1077 - 1087
publication: Protoplasma
publication_status: published
publisher: Springer
publist_id: '4987'
pubrep_id: '394'
quality_controlled: '1'
scopus_import: 1
status: public
title: The influence of heat stress on auxin distribution in transgenic B napus microspores
and microspore derived embryos
tmp:
image: /images/cc_by.png
legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
short: CC BY (4.0)
type: journal_article
user_id: 4435EBFC-F248-11E8-B48F-1D18A9856A87
volume: 251
year: '2014'
...
---
_id: '2062'
abstract:
- lang: eng
text: The success story of fast-spiking, parvalbumin-positive (PV+) GABAergic interneurons
(GABA, γ-aminobutyric acid) in the mammalian central nervous system is noteworthy.
In 1995, the properties of these interneurons were completely unknown. Twenty
years later, thanks to the massive use of subcellular patch-clamp techniques,
simultaneous multiple-cell recording, optogenetics, in vivo measurements, and
computational approaches, our knowledge about PV+ interneurons became more extensive
than for several types of pyramidal neurons. These findings have implications
beyond the “small world” of basic research on GABAergic cells. For example, the
results provide a first proof of principle that neuroscientists might be able
to close the gaps between the molecular, cellular, network, and behavioral levels,
representing one of the main challenges at the present time. Furthermore, the
results may form the basis for PV+ interneurons as therapeutic targets for brain
disease in the future. However, much needs to be learned about the basic function
of these interneurons before clinical neuroscientists will be able to use PV+
interneurons for therapeutic purposes.
article_number: '1255263'
author:
- first_name: Hua
full_name: Hu, Hua
id: 4AC0145C-F248-11E8-B48F-1D18A9856A87
last_name: Hu
- first_name: Jian
full_name: Gan, Jian
id: 3614E438-F248-11E8-B48F-1D18A9856A87
last_name: Gan
- first_name: Peter M
full_name: Jonas, Peter M
id: 353C1B58-F248-11E8-B48F-1D18A9856A87
last_name: Jonas
orcid: 0000-0001-5001-4804
citation:
ama: 'Hu H, Gan J, Jonas PM. Fast-spiking parvalbumin^+ GABAergic interneurons:
From cellular design to microcircuit function. Science. 2014;345(6196).
doi:10.1126/science.1255263'
apa: 'Hu, H., Gan, J., & Jonas, P. M. (2014). Fast-spiking parvalbumin^+ GABAergic
interneurons: From cellular design to microcircuit function. Science. American
Association for the Advancement of Science. https://doi.org/10.1126/science.1255263'
chicago: 'Hu, Hua, Jian Gan, and Peter M Jonas. “Fast-Spiking Parvalbumin^+ GABAergic
Interneurons: From Cellular Design to Microcircuit Function.” Science.
American Association for the Advancement of Science, 2014. https://doi.org/10.1126/science.1255263.'
ieee: 'H. Hu, J. Gan, and P. M. Jonas, “Fast-spiking parvalbumin^+ GABAergic interneurons:
From cellular design to microcircuit function,” Science, vol. 345, no.
6196. American Association for the Advancement of Science, 2014.'
ista: 'Hu H, Gan J, Jonas PM. 2014. Fast-spiking parvalbumin^+ GABAergic interneurons:
From cellular design to microcircuit function. Science. 345(6196), 1255263.'
mla: 'Hu, Hua, et al. “Fast-Spiking Parvalbumin^+ GABAergic Interneurons: From Cellular
Design to Microcircuit Function.” Science, vol. 345, no. 6196, 1255263,
American Association for the Advancement of Science, 2014, doi:10.1126/science.1255263.'
short: H. Hu, J. Gan, P.M. Jonas, Science 345 (2014).
date_created: 2018-12-11T11:55:29Z
date_published: 2014-08-01T00:00:00Z
date_updated: 2021-01-12T06:55:03Z
day: '01'
ddc:
- '570'
department:
- _id: PeJo
doi: 10.1126/science.1255263
ec_funded: 1
file:
- access_level: open_access
checksum: a0036a589037d37e86364fa25cc0a82f
content_type: application/pdf
creator: system
date_created: 2018-12-12T10:16:00Z
date_updated: 2020-07-14T12:45:27Z
file_id: '5185'
file_name: IST-2017-821-v1+1_1255263JonasPVReviewTextR_Final.pdf
file_size: 215514
relation: main_file
- access_level: open_access
checksum: e1f57d2713725449cb898fdcb8ef47b8
content_type: application/pdf
creator: system
date_created: 2018-12-12T10:16:01Z
date_updated: 2020-07-14T12:45:27Z
file_id: '5186'
file_name: IST-2017-821-v1+2_1255263JonasPVReviewFigures_Final.pdf
file_size: 1732723
relation: main_file
file_date_updated: 2020-07-14T12:45:27Z
has_accepted_license: '1'
intvolume: ' 345'
issue: '6196'
language:
- iso: eng
month: '08'
oa: 1
oa_version: Submitted Version
project:
- _id: 25C26B1E-B435-11E9-9278-68D0E5697425
call_identifier: FWF
grant_number: P24909-B24
name: Mechanisms of transmitter release at GABAergic synapses
- _id: 25C0F108-B435-11E9-9278-68D0E5697425
call_identifier: FP7
grant_number: '268548'
name: Nanophysiology of fast-spiking, parvalbumin-expressing GABAergic interneurons
publication: Science
publication_status: published
publisher: American Association for the Advancement of Science
publist_id: '4984'
pubrep_id: '821'
quality_controlled: '1'
scopus_import: 1
status: public
title: 'Fast-spiking parvalbumin^+ GABAergic interneurons: From cellular design to
microcircuit function'
type: journal_article
user_id: 4435EBFC-F248-11E8-B48F-1D18A9856A87
volume: 345
year: '2014'
...
---
_id: '2058'
abstract:
- lang: eng
text: We present a method for smoothly blending between existing liquid animations.
We introduce a semi-automatic method for matching two existing liquid animations,
which we use to create new fluid motion that plausibly interpolates the input.
Our contributions include a new space-time non-rigid iterative closest point algorithm
that incorporates user guidance, a subsampling technique for efficient registration
of meshes with millions of vertices, and a fast surface extraction algorithm that
produces 3D triangle meshes from a 4D space-time surface. Our technique can be
used to instantly create hundreds of new simulations, or to interactively explore
complex parameter spaces. Our method is guaranteed to produce output that does
not deviate from the input animations, and it generalizes to multiple dimensions.
Because our method runs at interactive rates after the initial precomputation
step, it has potential applications in games and training simulations.
article_number: '137'
article_processing_charge: No
author:
- first_name: Karthik
full_name: Raveendran, Karthik
last_name: Raveendran
- first_name: Christopher J
full_name: Wojtan, Christopher J
id: 3C61F1D2-F248-11E8-B48F-1D18A9856A87
last_name: Wojtan
orcid: 0000-0001-6646-5546
- first_name: Nils
full_name: Thuerey, Nils
last_name: Thuerey
- first_name: Greg
full_name: Türk, Greg
last_name: Türk
citation:
ama: 'Raveendran K, Wojtan C, Thuerey N, Türk G. Blending liquids. In: ACM Transactions
on Graphics. Vol 33. ACM; 2014. doi:10.1145/2601097.2601126'
apa: 'Raveendran, K., Wojtan, C., Thuerey, N., & Türk, G. (2014). Blending liquids.
In ACM Transactions on Graphics (Vol. 33). Vancouver, Canada: ACM. https://doi.org/10.1145/2601097.2601126'
chicago: Raveendran, Karthik, Chris Wojtan, Nils Thuerey, and Greg Türk. “Blending
Liquids.” In ACM Transactions on Graphics, Vol. 33. ACM, 2014. https://doi.org/10.1145/2601097.2601126.
ieee: K. Raveendran, C. Wojtan, N. Thuerey, and G. Türk, “Blending liquids,” in
ACM Transactions on Graphics, Vancouver, Canada, 2014, vol. 33, no. 4.
ista: 'Raveendran K, Wojtan C, Thuerey N, Türk G. 2014. Blending liquids. ACM Transactions
on Graphics. SIGGRAPH: International Conference and Exhibition on Computer Graphics
and Interactive Techniques vol. 33, 137.'
mla: Raveendran, Karthik, et al. “Blending Liquids.” ACM Transactions on Graphics,
vol. 33, no. 4, 137, ACM, 2014, doi:10.1145/2601097.2601126.
short: K. Raveendran, C. Wojtan, N. Thuerey, G. Türk, in:, ACM Transactions on Graphics,
ACM, 2014.
conference:
end_date: 2014-08-14
location: Vancouver, Canada
name: 'SIGGRAPH: International Conference and Exhibition on Computer Graphics and
Interactive Techniques'
start_date: 2014-08-10
date_created: 2018-12-11T11:55:28Z
date_published: 2014-07-01T00:00:00Z
date_updated: 2022-08-25T14:02:46Z
day: '01'
ddc:
- '000'
department:
- _id: ChWo
doi: 10.1145/2601097.2601126
file:
- access_level: open_access
checksum: 1752760a2e71e254537f31c0d10d9c6c
content_type: application/pdf
creator: system
date_created: 2018-12-12T10:08:27Z
date_updated: 2020-07-14T12:45:27Z
file_id: '4688'
file_name: IST-2016-606-v1+1_BlendingLiquids-Preprint.pdf
file_size: 8387384
relation: main_file
file_date_updated: 2020-07-14T12:45:27Z
has_accepted_license: '1'
intvolume: ' 33'
issue: '4'
language:
- iso: eng
month: '07'
oa: 1
oa_version: Submitted Version
project:
- _id: 25636330-B435-11E9-9278-68D0E5697425
grant_number: 11-NSF-1070
name: ROOTS Genome-wide Analysis of Root Traits
publication: ACM Transactions on Graphics
publication_status: published
publisher: ACM
publist_id: '4988'
pubrep_id: '606'
quality_controlled: '1'
scopus_import: '1'
status: public
title: Blending liquids
type: conference
user_id: 3E5EF7F0-F248-11E8-B48F-1D18A9856A87
volume: 33
year: '2014'
...