---
_id: '1710'
abstract:
- lang: eng
text: 'We consider the hollow on the half-plane {(x, y) : y ≤ 0} ⊂ ℝ2 defined by
a function u : (-1, 1) → ℝ, u(x) < 0, and a vertical flow of point particles
incident on the hollow. It is assumed that u satisfies the so-called single impact
condition (SIC): each incident particle is elastically reflected by graph(u) and
goes away without hitting the graph of u anymore. We solve the problem: find the
function u minimizing the force of resistance created by the flow. We show that
the graph of the minimizer is formed by two arcs of parabolas symmetric to each
other with respect to the y-axis. Assuming that the resistance of u ≡ 0 equals
1, we show that the minimal resistance equals π/2 - 2arctan(1/2) ≈ 0.6435. This
result completes the previously obtained result [SIAM J. Math. Anal., 46 (2014),
pp. 2730-2742] stating in particular that the minimal resistance of a hollow in
higher dimensions equals 0.5. We additionally consider a similar problem of minimal
resistance, where the hollow in the half-space {(x1,...,xd,y) : y ≤ 0} ⊂ ℝd+1
is defined by a radial function U satisfying the SIC, U(x) = u(|x|), with x =
(x1,...,xd), u(ξ) < 0 for 0 ≤ ξ < 1, and u(ξ) = 0 for ξ ≥ 1, and the flow
is parallel to the y-axis. The minimal resistance is greater than 0.5 (and coincides
with 0.6435 when d = 1) and converges to 0.5 as d → ∞.'
author:
- first_name: Arseniy
full_name: Akopyan, Arseniy
id: 430D2C90-F248-11E8-B48F-1D18A9856A87
last_name: Akopyan
orcid: 0000-0002-2548-617X
- first_name: Alexander
full_name: Plakhov, Alexander
last_name: Plakhov
citation:
ama: Akopyan A, Plakhov A. Minimal resistance of curves under the single impact
assumption. Society for Industrial and Applied Mathematics. 2015;47(4):2754-2769.
doi:10.1137/140993843
apa: Akopyan, A., & Plakhov, A. (2015). Minimal resistance of curves under the
single impact assumption. Society for Industrial and Applied Mathematics.
SIAM. https://doi.org/10.1137/140993843
chicago: Akopyan, Arseniy, and Alexander Plakhov. “Minimal Resistance of Curves
under the Single Impact Assumption.” Society for Industrial and Applied Mathematics.
SIAM, 2015. https://doi.org/10.1137/140993843.
ieee: A. Akopyan and A. Plakhov, “Minimal resistance of curves under the single
impact assumption,” Society for Industrial and Applied Mathematics, vol.
47, no. 4. SIAM, pp. 2754–2769, 2015.
ista: Akopyan A, Plakhov A. 2015. Minimal resistance of curves under the single
impact assumption. Society for Industrial and Applied Mathematics. 47(4), 2754–2769.
mla: Akopyan, Arseniy, and Alexander Plakhov. “Minimal Resistance of Curves under
the Single Impact Assumption.” Society for Industrial and Applied Mathematics,
vol. 47, no. 4, SIAM, 2015, pp. 2754–69, doi:10.1137/140993843.
short: A. Akopyan, A. Plakhov, Society for Industrial and Applied Mathematics 47
(2015) 2754–2769.
date_created: 2018-12-11T11:53:36Z
date_published: 2015-07-14T00:00:00Z
date_updated: 2021-01-12T06:52:41Z
day: '14'
department:
- _id: HeEd
doi: 10.1137/140993843
ec_funded: 1
intvolume: ' 47'
issue: '4'
language:
- iso: eng
main_file_link:
- open_access: '1'
url: http://arxiv.org/abs/1410.3736
month: '07'
oa: 1
oa_version: Preprint
page: 2754 - 2769
project:
- _id: 25681D80-B435-11E9-9278-68D0E5697425
call_identifier: FP7
grant_number: '291734'
name: International IST Postdoc Fellowship Programme
publication: Society for Industrial and Applied Mathematics
publication_status: published
publisher: SIAM
publist_id: '5423'
quality_controlled: '1'
scopus_import: 1
status: public
title: Minimal resistance of curves under the single impact assumption
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 47
year: '2015'
...
---
_id: '1730'
abstract:
- lang: eng
text: How much cutting is needed to simplify the topology of a surface? We provide
bounds for several instances of this question, for the minimum length of topologically
non-trivial closed curves, pants decompositions, and cut graphs with a given combinatorial
map in triangulated combinatorial surfaces (or their dual cross-metric counterpart).
Our work builds upon Riemannian systolic inequalities, which bound the minimum
length of non-trivial closed curves in terms of the genus and the area of the
surface. We first describe a systematic way to translate Riemannian systolic inequalities
to a discrete setting, and vice-versa. This implies a conjecture by Przytycka
and Przytycki (Graph structure theory. Contemporary Mathematics, vol. 147, 1993),
a number of new systolic inequalities in the discrete setting, and the fact that
a theorem of Hutchinson on the edge-width of triangulated surfaces and Gromov’s
systolic inequality for surfaces are essentially equivalent. We also discuss how
these proofs generalize to higher dimensions. Then we focus on topological decompositions
of surfaces. Relying on ideas of Buser, we prove the existence of pants decompositions
of length O(g^(3/2)n^(1/2)) for any triangulated combinatorial surface of genus
g with n triangles, and describe an O(gn)-time algorithm to compute such a decomposition.
Finally, we consider the problem of embedding a cut graph (or more generally a
cellular graph) with a given combinatorial map on a given surface. Using random
triangulations, we prove (essentially) that, for any choice of a combinatorial
map, there are some surfaces on which any cellular embedding with that combinatorial
map has length superlinear in the number of triangles of the triangulated combinatorial
surface. There is also a similar result for graphs embedded on polyhedral triangulations.
author:
- first_name: Éric
full_name: Colin De Verdière, Éric
last_name: Colin De Verdière
- first_name: Alfredo
full_name: Hubard, Alfredo
last_name: Hubard
- first_name: Arnaud N
full_name: De Mesmay, Arnaud N
id: 3DB2F25C-F248-11E8-B48F-1D18A9856A87
last_name: De Mesmay
citation:
ama: Colin De Verdière É, Hubard A, de Mesmay AN. Discrete systolic inequalities
and decompositions of triangulated surfaces. Discrete & Computational Geometry.
2015;53(3):587-620. doi:10.1007/s00454-015-9679-9
apa: Colin De Verdière, É., Hubard, A., & de Mesmay, A. N. (2015). Discrete
systolic inequalities and decompositions of triangulated surfaces. Discrete
& Computational Geometry. Springer. https://doi.org/10.1007/s00454-015-9679-9
chicago: Colin De Verdière, Éric, Alfredo Hubard, and Arnaud N de Mesmay. “Discrete
Systolic Inequalities and Decompositions of Triangulated Surfaces.” Discrete
& Computational Geometry. Springer, 2015. https://doi.org/10.1007/s00454-015-9679-9.
ieee: É. Colin De Verdière, A. Hubard, and A. N. de Mesmay, “Discrete systolic inequalities
and decompositions of triangulated surfaces,” Discrete & Computational
Geometry, vol. 53, no. 3. Springer, pp. 587–620, 2015.
ista: Colin De Verdière É, Hubard A, de Mesmay AN. 2015. Discrete systolic inequalities
and decompositions of triangulated surfaces. Discrete & Computational Geometry.
53(3), 587–620.
mla: Colin De Verdière, Éric, et al. “Discrete Systolic Inequalities and Decompositions
of Triangulated Surfaces.” Discrete & Computational Geometry, vol.
53, no. 3, Springer, 2015, pp. 587–620, doi:10.1007/s00454-015-9679-9.
short: É. Colin De Verdière, A. Hubard, A.N. de Mesmay, Discrete & Computational
Geometry 53 (2015) 587–620.
date_created: 2018-12-11T11:53:42Z
date_published: 2015-04-02T00:00:00Z
date_updated: 2021-01-12T06:52:49Z
day: '02'
department:
- _id: UlWa
doi: 10.1007/s00454-015-9679-9
intvolume: ' 53'
issue: '3'
language:
- iso: eng
main_file_link:
- open_access: '1'
url: http://arxiv.org/abs/1408.4036
month: '04'
oa: 1
oa_version: Preprint
page: 587 - 620
publication: Discrete & Computational Geometry
publication_status: published
publisher: Springer
publist_id: '5397'
quality_controlled: '1'
scopus_import: 1
status: public
title: Discrete systolic inequalities and decompositions of triangulated surfaces
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 53
year: '2015'
...
---
_id: '1728'
abstract:
- lang: eng
text: 'In the vertebrate neural tube, the morphogen Sonic Hedgehog (Shh) establishes
a characteristic pattern of gene expression. Here we quantify the Shh gradient
in the developing mouse neural tube and show that while the amplitude of the gradient
increases over time, the activity of the pathway transcriptional effectors, Gli
proteins, initially increases but later decreases. Computational analysis of the
pathway suggests three mechanisms that could contribute to this adaptation: transcriptional
upregulation of the inhibitory receptor Ptch1, transcriptional downregulation
of Gli and the differential stability of active and inactive Gli isoforms. Consistent
with this, Gli2 protein expression is downregulated during neural tube patterning
and adaptation continues when the pathway is stimulated downstream of Ptch1. Moreover,
the Shh-induced upregulation of Gli2 transcription prevents Gli activity levels
from adapting in a different cell type, NIH3T3 fibroblasts, despite the upregulation
of Ptch1. Multiple mechanisms therefore contribute to the intracellular dynamics
of Shh signalling, resulting in different signalling dynamics in different cell
types.'
acknowledgement: C.P.B. gratefully acknowledges funding from the Wellcome Trust through
a Research Career Development Fellowship (097319/Z/11/Z). This work was supported
by the Medical Research Council (U117560541) and Wellcome Trust (WT098326MA, WT098325MA).
author:
- first_name: Michael
full_name: Cohen, Michael H
last_name: Cohen
- first_name: Anna
full_name: Anna Kicheva
id: 3959A2A0-F248-11E8-B48F-1D18A9856A87
last_name: Kicheva
orcid: 0000-0003-4509-4998
- first_name: Ana
full_name: Ribeiro, Ana C
last_name: Ribeiro
- first_name: Robert
full_name: Blassberg, Robert A
last_name: Blassberg
- first_name: Karen
full_name: Page, Karen M
last_name: Page
- first_name: Chris
full_name: Barnes, Chris P
last_name: Barnes
- first_name: James
full_name: Briscoe, James
last_name: Briscoe
citation:
ama: Cohen M, Kicheva A, Ribeiro A, et al. Ptch1 and Gli regulate Shh signalling
dynamics via multiple mechanisms. Nature Communications. 2015;6. doi:10.1038/ncomms7709
apa: Cohen, M., Kicheva, A., Ribeiro, A., Blassberg, R., Page, K., Barnes, C., &
Briscoe, J. (2015). Ptch1 and Gli regulate Shh signalling dynamics via multiple
mechanisms. Nature Communications. Nature Publishing Group. https://doi.org/10.1038/ncomms7709
chicago: Cohen, Michael, Anna Kicheva, Ana Ribeiro, Robert Blassberg, Karen Page,
Chris Barnes, and James Briscoe. “Ptch1 and Gli Regulate Shh Signalling Dynamics
via Multiple Mechanisms.” Nature Communications. Nature Publishing Group,
2015. https://doi.org/10.1038/ncomms7709.
ieee: M. Cohen et al., “Ptch1 and Gli regulate Shh signalling dynamics via
multiple mechanisms,” Nature Communications, vol. 6. Nature Publishing
Group, 2015.
ista: Cohen M, Kicheva A, Ribeiro A, Blassberg R, Page K, Barnes C, Briscoe J. 2015.
Ptch1 and Gli regulate Shh signalling dynamics via multiple mechanisms. Nature
Communications. 6.
mla: Cohen, Michael, et al. “Ptch1 and Gli Regulate Shh Signalling Dynamics via
Multiple Mechanisms.” Nature Communications, vol. 6, Nature Publishing
Group, 2015, doi:10.1038/ncomms7709.
short: M. Cohen, A. Kicheva, A. Ribeiro, R. Blassberg, K. Page, C. Barnes, J. Briscoe,
Nature Communications 6 (2015).
date_created: 2018-12-11T11:53:42Z
date_published: 2015-04-02T00:00:00Z
date_updated: 2021-01-12T06:52:48Z
day: '02'
doi: 10.1038/ncomms7709
extern: 1
intvolume: ' 6'
month: '04'
publication: Nature Communications
publication_status: published
publisher: Nature Publishing Group
publist_id: '5399'
quality_controlled: 0
status: public
title: Ptch1 and Gli regulate Shh signalling dynamics via multiple mechanisms
tmp:
image: /images/cc_by.png
legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
short: CC BY (4.0)
type: journal_article
volume: 6
year: '2015'
...
---
_id: '1735'
abstract:
- lang: eng
text: This work presents a method for efficiently simplifying the pressure projection
step in a liquid simulation. We first devise a straightforward dimension reduction
technique that dramatically reduces the cost of solving the pressure projection.
Next, we introduce a novel change of basis that satisfies free-surface boundary
conditions exactly, regardless of the accuracy of the pressure solve. When combined,
these ideas greatly reduce the computational complexity of the pressure solve
without compromising free surface boundary conditions at the highest level of
detail. Our techniques are easy to parallelize, and they effectively eliminate
the computational bottleneck for large liquid simulations.
acknowledgement: The first author was supported by a JSPS Postdoctoral Fellowship
for Research Abroad
author:
- first_name: Ryoichi
full_name: Ando, Ryoichi
last_name: Ando
- first_name: Nils
full_name: Thürey, Nils
last_name: Thürey
- first_name: Christopher J
full_name: Wojtan, Christopher J
id: 3C61F1D2-F248-11E8-B48F-1D18A9856A87
last_name: Wojtan
orcid: 0000-0001-6646-5546
citation:
ama: Ando R, Thürey N, Wojtan C. A dimension-reduced pressure solver for liquid
simulations. Computer Graphics Forum. 2015;34(2):473-480. doi:10.1111/cgf.12576
apa: Ando, R., Thürey, N., & Wojtan, C. (2015). A dimension-reduced pressure
solver for liquid simulations. Computer Graphics Forum. Wiley. https://doi.org/10.1111/cgf.12576
chicago: Ando, Ryoichi, Nils Thürey, and Chris Wojtan. “A Dimension-Reduced Pressure
Solver for Liquid Simulations.” Computer Graphics Forum. Wiley, 2015. https://doi.org/10.1111/cgf.12576.
ieee: R. Ando, N. Thürey, and C. Wojtan, “A dimension-reduced pressure solver for
liquid simulations,” Computer Graphics Forum, vol. 34, no. 2. Wiley, pp.
473–480, 2015.
ista: Ando R, Thürey N, Wojtan C. 2015. A dimension-reduced pressure solver for
liquid simulations. Computer Graphics Forum. 34(2), 473–480.
mla: Ando, Ryoichi, et al. “A Dimension-Reduced Pressure Solver for Liquid Simulations.”
Computer Graphics Forum, vol. 34, no. 2, Wiley, 2015, pp. 473–80, doi:10.1111/cgf.12576.
short: R. Ando, N. Thürey, C. Wojtan, Computer Graphics Forum 34 (2015) 473–480.
date_created: 2018-12-11T11:53:44Z
date_published: 2015-05-01T00:00:00Z
date_updated: 2023-02-23T10:12:11Z
day: '01'
ddc:
- '000'
department:
- _id: ChWo
doi: 10.1111/cgf.12576
file:
- access_level: open_access
checksum: 590752bf977855b337a80f78a9bc2404
content_type: application/pdf
creator: system
date_created: 2018-12-12T10:16:30Z
date_updated: 2020-07-14T12:45:15Z
file_id: '5218'
file_name: IST-2016-607-v1+1_coarsegrid.pdf
file_size: 6312352
relation: main_file
file_date_updated: 2020-07-14T12:45:15Z
has_accepted_license: '1'
intvolume: ' 34'
issue: '2'
language:
- iso: eng
month: '05'
oa: 1
oa_version: Submitted Version
page: 473 - 480
publication: Computer Graphics Forum
publication_status: published
publisher: Wiley
publist_id: '5389'
pubrep_id: '607'
quality_controlled: '1'
scopus_import: 1
status: public
title: A dimension-reduced pressure solver for liquid simulations
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 34
year: '2015'
...
---
_id: '1734'
abstract:
- lang: eng
text: Facial appearance capture is now firmly established within academic research
and used extensively across various application domains, perhaps most prominently
in the entertainment industry through the design of virtual characters in video
games and films. While significant progress has occurred over the last two decades,
no single survey currently exists that discusses the similarities, differences,
and practical considerations of the available appearance capture techniques as
applied to human faces. A central difficulty of facial appearance capture is the
way light interacts with skin-which has a complex multi-layered structure-and
the interactions that occur below the skin surface can, by definition, only be
observed indirectly. In this report, we distinguish between two broad strategies
for dealing with this complexity. "Image-based methods" try to exhaustively
capture the exact face appearance under different lighting and viewing conditions,
and then render the face through weighted image combinations. "Parametric
methods" instead fit the captured reflectance data to some parametric appearance
model used during rendering, allowing for a more lightweight and flexible representation
but at the cost of potentially increased rendering complexity or inexact reproduction.
The goal of this report is to provide an overview that can guide practitioners
and researchers in assessing the tradeoffs between current approaches and identifying
directions for future advances in facial appearance capture.
author:
- first_name: Oliver
full_name: Klehm, Oliver
last_name: Klehm
- first_name: Fabrice
full_name: Rousselle, Fabrice
last_name: Rousselle
- first_name: Marios
full_name: Papas, Marios
last_name: Papas
- first_name: Derek
full_name: Bradley, Derek
last_name: Bradley
- first_name: Christophe
full_name: Hery, Christophe
last_name: Hery
- first_name: Bernd
full_name: Bickel, Bernd
id: 49876194-F248-11E8-B48F-1D18A9856A87
last_name: Bickel
orcid: 0000-0001-6511-9385
- first_name: Wojciech
full_name: Jarosz, Wojciech
last_name: Jarosz
- first_name: Thabo
full_name: Beeler, Thabo
last_name: Beeler
citation:
ama: Klehm O, Rousselle F, Papas M, et al. Recent advances in facial appearance
capture. Computer Graphics Forum. 2015;34(2):709-733. doi:10.1111/cgf.12594
apa: Klehm, O., Rousselle, F., Papas, M., Bradley, D., Hery, C., Bickel, B., … Beeler,
T. (2015). Recent advances in facial appearance capture. Computer Graphics
Forum. Wiley-Blackwell. https://doi.org/10.1111/cgf.12594
chicago: Klehm, Oliver, Fabrice Rousselle, Marios Papas, Derek Bradley, Christophe
Hery, Bernd Bickel, Wojciech Jarosz, and Thabo Beeler. “Recent Advances in Facial
Appearance Capture.” Computer Graphics Forum. Wiley-Blackwell, 2015. https://doi.org/10.1111/cgf.12594.
ieee: O. Klehm et al., “Recent advances in facial appearance capture,” Computer
Graphics Forum, vol. 34, no. 2. Wiley-Blackwell, pp. 709–733, 2015.
ista: Klehm O, Rousselle F, Papas M, Bradley D, Hery C, Bickel B, Jarosz W, Beeler
T. 2015. Recent advances in facial appearance capture. Computer Graphics Forum.
34(2), 709–733.
mla: Klehm, Oliver, et al. “Recent Advances in Facial Appearance Capture.” Computer
Graphics Forum, vol. 34, no. 2, Wiley-Blackwell, 2015, pp. 709–33, doi:10.1111/cgf.12594.
short: O. Klehm, F. Rousselle, M. Papas, D. Bradley, C. Hery, B. Bickel, W. Jarosz,
T. Beeler, Computer Graphics Forum 34 (2015) 709–733.
date_created: 2018-12-11T11:53:43Z
date_published: 2015-05-01T00:00:00Z
date_updated: 2021-01-12T06:52:52Z
day: '01'
department:
- _id: BeBi
doi: 10.1111/cgf.12594
intvolume: ' 34'
issue: '2'
language:
- iso: eng
main_file_link:
- url: https://graphics.ethz.ch/~mpapas/publications/fac_star.pdf
month: '05'
oa_version: None
page: 709 - 733
publication: Computer Graphics Forum
publication_status: published
publisher: Wiley-Blackwell
publist_id: '5391'
quality_controlled: '1'
scopus_import: 1
status: public
title: Recent advances in facial appearance capture
type: journal_article
user_id: 3E5EF7F0-F248-11E8-B48F-1D18A9856A87
volume: 34
year: '2015'
...
---
_id: '1789'
abstract:
- lang: eng
text: Intellectual disability (ID) has an estimated prevalence of 2-3%. Due to its
extreme heterogeneity, the genetic basis of ID remains elusive in many cases.
Recently, whole exome sequencing (WES) studies revealed that a large proportion
of sporadic cases are caused by de novo gene variants. To identify further genes
involved in ID, we performed WES in 250 patients with unexplained ID and their
unaffected parents and included exomes of 51 previously sequenced child-parents
trios in the analysis. Exome analysis revealed de novo intragenic variants in
SET domain-containing 5 (SETD5) in two patients. One patient carried a nonsense
variant, and the other an 81 bp deletion located across a splice-donor site. Chromosomal
microarray diagnostics further identified four de novo non-recurrent microdeletions
encompassing SETD5. CRISPR/Cas9 mutation modelling of the two intragenic variants
demonstrated nonsense-mediated decay of the resulting transcripts, pointing to
a loss-of-function (LoF) and haploinsufficiency as the common disease-causing
mechanism of intragenic SETD5 sequence variants and SETD5-containing microdeletions.
In silico domain prediction of SETD5, a predicted SET domain-containing histone
methyltransferase (HMT), substantiated the presence of a SET domain and identified
a novel putative PHD domain, strengthening a functional link to well-known histone-modifying
ID genes. All six patients presented with ID and certain facial dysmorphisms,
suggesting that SETD5 sequence variants contribute substantially to the microdeletion
3p25.3 phenotype. The present report of two SETD5 LoF variants in 301 patients
demonstrates a prevalence of 0.7% and thus SETD5 variants as a relatively frequent
cause of ID.
author:
- first_name: Alma
full_name: Kuechler, Alma
last_name: Kuechler
- first_name: Alexander
full_name: Zink, Alexander
last_name: Zink
- first_name: Thomas
full_name: Wieland, Thomas
last_name: Wieland
- first_name: Hermann
full_name: Lüdecke, Hermann
last_name: Lüdecke
- first_name: Kirsten
full_name: Cremer, Kirsten
last_name: Cremer
- first_name: Leonardo
full_name: Salviati, Leonardo
last_name: Salviati
- first_name: Pamela
full_name: Magini, Pamela
last_name: Magini
- first_name: Kimia
full_name: Najafi, Kimia
last_name: Najafi
- first_name: Christiane
full_name: Zweier, Christiane
last_name: Zweier
- first_name: Johanna
full_name: Czeschik, Johanna
last_name: Czeschik
- first_name: Stefan
full_name: Aretz, Stefan
last_name: Aretz
- first_name: Sabine
full_name: Endele, Sabine
last_name: Endele
- first_name: Federica
full_name: Tamburrino, Federica
last_name: Tamburrino
- first_name: Claudia
full_name: Pinato, Claudia
last_name: Pinato
- first_name: Maurizio
full_name: Clementi, Maurizio
last_name: Clementi
- first_name: Jasmin
full_name: Gundlach, Jasmin
last_name: Gundlach
- first_name: Carina
full_name: Maylahn, Carina
last_name: Maylahn
- first_name: Laura
full_name: Mazzanti, Laura
last_name: Mazzanti
- first_name: Eva
full_name: Wohlleber, Eva
last_name: Wohlleber
- first_name: Thomas
full_name: Schwarzmayr, Thomas
last_name: Schwarzmayr
- first_name: Roxana
full_name: Kariminejad, Roxana
last_name: Kariminejad
- first_name: Avner
full_name: Schlessinger, Avner
last_name: Schlessinger
- first_name: Dagmar
full_name: Wieczorek, Dagmar
last_name: Wieczorek
- first_name: Tim
full_name: Strom, Tim
last_name: Strom
- first_name: Gaia
full_name: Novarino, Gaia
id: 3E57A680-F248-11E8-B48F-1D18A9856A87
last_name: Novarino
orcid: 0000-0002-7673-7178
- first_name: Hartmut
full_name: Engels, Hartmut
last_name: Engels
citation:
ama: Kuechler A, Zink A, Wieland T, et al. Loss-of-function variants of SETD5 cause
intellectual disability and the core phenotype of microdeletion 3p25.3 syndrome.
European Journal of Human Genetics. 2015;23(6):753-760. doi:10.1038/ejhg.2014.165
apa: Kuechler, A., Zink, A., Wieland, T., Lüdecke, H., Cremer, K., Salviati, L.,
… Engels, H. (2015). Loss-of-function variants of SETD5 cause intellectual disability
and the core phenotype of microdeletion 3p25.3 syndrome. European Journal of
Human Genetics. Nature Publishing Group. https://doi.org/10.1038/ejhg.2014.165
chicago: Kuechler, Alma, Alexander Zink, Thomas Wieland, Hermann Lüdecke, Kirsten
Cremer, Leonardo Salviati, Pamela Magini, et al. “Loss-of-Function Variants of
SETD5 Cause Intellectual Disability and the Core Phenotype of Microdeletion 3p25.3
Syndrome.” European Journal of Human Genetics. Nature Publishing Group,
2015. https://doi.org/10.1038/ejhg.2014.165.
ieee: A. Kuechler et al., “Loss-of-function variants of SETD5 cause intellectual
disability and the core phenotype of microdeletion 3p25.3 syndrome,” European
Journal of Human Genetics, vol. 23, no. 6. Nature Publishing Group, pp. 753–760,
2015.
ista: Kuechler A, Zink A, Wieland T, Lüdecke H, Cremer K, Salviati L, Magini P,
Najafi K, Zweier C, Czeschik J, Aretz S, Endele S, Tamburrino F, Pinato C, Clementi
M, Gundlach J, Maylahn C, Mazzanti L, Wohlleber E, Schwarzmayr T, Kariminejad
R, Schlessinger A, Wieczorek D, Strom T, Novarino G, Engels H. 2015. Loss-of-function
variants of SETD5 cause intellectual disability and the core phenotype of microdeletion
3p25.3 syndrome. European Journal of Human Genetics. 23(6), 753–760.
mla: Kuechler, Alma, et al. “Loss-of-Function Variants of SETD5 Cause Intellectual
Disability and the Core Phenotype of Microdeletion 3p25.3 Syndrome.” European
Journal of Human Genetics, vol. 23, no. 6, Nature Publishing Group, 2015,
pp. 753–60, doi:10.1038/ejhg.2014.165.
short: A. Kuechler, A. Zink, T. Wieland, H. Lüdecke, K. Cremer, L. Salviati, P.
Magini, K. Najafi, C. Zweier, J. Czeschik, S. Aretz, S. Endele, F. Tamburrino,
C. Pinato, M. Clementi, J. Gundlach, C. Maylahn, L. Mazzanti, E. Wohlleber, T.
Schwarzmayr, R. Kariminejad, A. Schlessinger, D. Wieczorek, T. Strom, G. Novarino,
H. Engels, European Journal of Human Genetics 23 (2015) 753–760.
date_created: 2018-12-11T11:54:01Z
date_published: 2015-06-15T00:00:00Z
date_updated: 2021-01-12T06:53:12Z
day: '15'
department:
- _id: GaNo
doi: 10.1038/ejhg.2014.165
external_id:
pmid:
- '25138099'
intvolume: ' 23'
issue: '6'
language:
- iso: eng
main_file_link:
- open_access: '1'
url: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4795044/
month: '06'
oa: 1
oa_version: Submitted Version
page: 753 - 760
pmid: 1
publication: European Journal of Human Genetics
publication_status: published
publisher: Nature Publishing Group
publist_id: '5324'
quality_controlled: '1'
status: public
title: Loss-of-function variants of SETD5 cause intellectual disability and the core
phenotype of microdeletion 3p25.3 syndrome
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 23
year: '2015'
...
---
_id: '1788'
abstract:
- lang: eng
text: We fabricate and characterize a microscale silicon opto-electromechanical
system whose mechanical motion is coupled capacitively to an electrical circuit
and optically via radiation pressure to a photonic crystal cavity. To achieve
large electromechanical interaction strength, we implement an inverse shadow mask
fabrication scheme which obtains capacitor gaps as small as 30 nm while maintaining
a silicon surface quality necessary for minimizing optical loss. Using the sensitive
optical read-out of the photonic crystal cavity, we characterize the linear and
nonlinear capacitive coupling to the fundamental ωm=2π = 63 MHz in-plane flexural
motion of the structure, showing that the large electromechanical coupling in
such devices may be suitable for realizing efficient microwave-to-optical signal
conversion.
acknowledgement: This work was supported by the DARPA MESO program, the AFOSR Hybrid
Nanophotonics MURI, the Institute for Quantum Information and Matter, an NSF Physics
Frontiers Center with support of the Gordon and Betty Moore Foundation, and the
Kavli Nanoscience Institute at Caltech. AP gratefully acknowledge funding from EU
through Marie Curie Actions, project NEMO (GA 298861). AT acknowledges partial financial
support from the ERC through the advanced grant SoulMan
author:
- first_name: Alessandro
full_name: Pitanti, Alessandro
last_name: Pitanti
- first_name: Johannes M
full_name: Johannes Fink
id: 4B591CBA-F248-11E8-B48F-1D18A9856A87
last_name: Fink
orcid: 0000-0001-8112-028X
- first_name: Amir
full_name: Safavi-Naeini, Amir H
last_name: Safavi Naeini
- first_name: Jeff
full_name: Hill, Jeff T
last_name: Hill
- first_name: Chan
full_name: Lei, Chan U
last_name: Lei
- first_name: Alessandro
full_name: Tredicucci, Alessandro
last_name: Tredicucci
- first_name: Oskar
full_name: Painter, Oskar J
last_name: Painter
citation:
ama: Pitanti A, Fink JM, Safavi Naeini A, et al. Strong opto-electro-mechanical
coupling in a silicon photonic crystal cavity. Optics Express. 2015;23(3):3196-3208.
doi:10.1364/OE.23.003196
apa: Pitanti, A., Fink, J. M., Safavi Naeini, A., Hill, J., Lei, C., Tredicucci,
A., & Painter, O. (2015). Strong opto-electro-mechanical coupling in a silicon
photonic crystal cavity. Optics Express. Optical Society of America. https://doi.org/10.1364/OE.23.003196
chicago: Pitanti, Alessandro, Johannes M Fink, Amir Safavi Naeini, Jeff Hill, Chan
Lei, Alessandro Tredicucci, and Oskar Painter. “Strong Opto-Electro-Mechanical
Coupling in a Silicon Photonic Crystal Cavity.” Optics Express. Optical
Society of America, 2015. https://doi.org/10.1364/OE.23.003196.
ieee: A. Pitanti et al., “Strong opto-electro-mechanical coupling in a silicon
photonic crystal cavity,” Optics Express, vol. 23, no. 3. Optical Society
of America, pp. 3196–3208, 2015.
ista: Pitanti A, Fink JM, Safavi Naeini A, Hill J, Lei C, Tredicucci A, Painter
O. 2015. Strong opto-electro-mechanical coupling in a silicon photonic crystal
cavity. Optics Express. 23(3), 3196–3208.
mla: Pitanti, Alessandro, et al. “Strong Opto-Electro-Mechanical Coupling in a Silicon
Photonic Crystal Cavity.” Optics Express, vol. 23, no. 3, Optical Society
of America, 2015, pp. 3196–208, doi:10.1364/OE.23.003196.
short: A. Pitanti, J.M. Fink, A. Safavi Naeini, J. Hill, C. Lei, A. Tredicucci,
O. Painter, Optics Express 23 (2015) 3196–3208.
date_created: 2018-12-11T11:54:01Z
date_published: 2015-02-09T00:00:00Z
date_updated: 2021-01-12T06:53:12Z
day: '09'
doi: 10.1364/OE.23.003196
extern: 1
intvolume: ' 23'
issue: '3'
month: '02'
page: 3196 - 3208
publication: Optics Express
publication_status: published
publisher: Optical Society of America
publist_id: '5325'
quality_controlled: 0
status: public
title: Strong opto-electro-mechanical coupling in a silicon photonic crystal cavity
type: journal_article
volume: 23
year: '2015'
...
---
_id: '1804'
abstract:
- lang: eng
text: It is known that in classical fluids turbulence typically occurs at high Reynolds
numbers. But can turbulence occur at low Reynolds numbers? Here we investigate
the transition to turbulence in the classic Taylor-Couette system in which the
rotating fluids are manufactured ferrofluids with magnetized nanoparticles embedded
in liquid carriers. We find that, in the presence of a magnetic field transverse
to the symmetry axis of the system, turbulence can occur at Reynolds numbers that
are at least one order of magnitude smaller than those in conventional fluids.
This is established by extensive computational ferrohydrodynamics through a detailed
investigation of transitions in the flow structure, and characterization of behaviors
of physical quantities such as the energy, the wave number, and the angular momentum
through the bifurcations. A finding is that, as the magnetic field is increased,
onset of turbulence can be determined accurately and reliably. Our results imply
that experimental investigation of turbulence may be feasible by using ferrofluids.
Our study of transition to and evolution of turbulence in the Taylor-Couette ferrofluidic
flow system provides insights into the challenging problem of turbulence control.
article_number: '10781'
author:
- first_name: Sebastian
full_name: Altmeyer, Sebastian
id: 2EE67FDC-F248-11E8-B48F-1D18A9856A87
last_name: Altmeyer
orcid: 0000-0001-5964-0203
- first_name: Younghae
full_name: Do, Younghae
last_name: Do
- first_name: Ying
full_name: Lai, Ying
last_name: Lai
citation:
ama: Altmeyer S, Do Y, Lai Y. Transition to turbulence in Taylor-Couette ferrofluidic
flow. Scientific Reports. 2015;5. doi:10.1038/srep10781
apa: Altmeyer, S., Do, Y., & Lai, Y. (2015). Transition to turbulence in Taylor-Couette
ferrofluidic flow. Scientific Reports. Nature Publishing Group. https://doi.org/10.1038/srep10781
chicago: Altmeyer, Sebastian, Younghae Do, and Ying Lai. “Transition to Turbulence
in Taylor-Couette Ferrofluidic Flow.” Scientific Reports. Nature Publishing
Group, 2015. https://doi.org/10.1038/srep10781.
ieee: S. Altmeyer, Y. Do, and Y. Lai, “Transition to turbulence in Taylor-Couette
ferrofluidic flow,” Scientific Reports, vol. 5. Nature Publishing Group,
2015.
ista: Altmeyer S, Do Y, Lai Y. 2015. Transition to turbulence in Taylor-Couette
ferrofluidic flow. Scientific Reports. 5, 10781.
mla: Altmeyer, Sebastian, et al. “Transition to Turbulence in Taylor-Couette Ferrofluidic
Flow.” Scientific Reports, vol. 5, 10781, Nature Publishing Group, 2015,
doi:10.1038/srep10781.
short: S. Altmeyer, Y. Do, Y. Lai, Scientific Reports 5 (2015).
date_created: 2018-12-11T11:54:06Z
date_published: 2015-06-12T00:00:00Z
date_updated: 2021-01-12T06:53:18Z
day: '12'
ddc:
- '530'
department:
- _id: BjHo
doi: 10.1038/srep10781
file:
- access_level: open_access
checksum: 7716f582f8c9d82d8f2bf80bf896b440
content_type: application/pdf
creator: system
date_created: 2018-12-12T10:17:26Z
date_updated: 2020-07-14T12:45:16Z
file_id: '5280'
file_name: IST-2016-450-v1+1_srep10781.pdf
file_size: 2449723
relation: main_file
file_date_updated: 2020-07-14T12:45:16Z
has_accepted_license: '1'
intvolume: ' 5'
language:
- iso: eng
month: '06'
oa: 1
oa_version: Published Version
publication: Scientific Reports
publication_status: published
publisher: Nature Publishing Group
publist_id: '5306'
pubrep_id: '450'
quality_controlled: '1'
scopus_import: 1
status: public
title: Transition to turbulence in Taylor-Couette ferrofluidic flow
tmp:
image: /images/cc_by.png
legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
short: CC BY (4.0)
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 5
year: '2015'
...
---
_id: '1803'
abstract:
- lang: eng
text: Repeated stress has been suggested to underlie learning and memory deficits
via the basolateral amygdala (BLA) and the hippocampus; however, the functional
contribution of BLA inputs to the hippocampus and their molecular repercussions
are not well understood. Here we show that repeated stress is accompanied by generation
of the Cdk5 (cyclin-dependent kinase 5)-activator p25, up-regulation and phosphorylation
of glucocorticoid receptors, increased HDAC2 expression, and reduced expression
of memoryrelated genes in the hippocampus. A combination of optogenetic and pharmacosynthetic
approaches shows that BLA activation is both necessary and sufficient for stress-associated
molecular changes and memory impairments. Furthermore, we show that this effect
relies on direct glutamatergic projections from the BLA to the dorsal hippocampus.
Finally, we show that p25 generation is necessary for the stress-induced memory
dysfunction. Taken together, our data provide a neural circuit model for stress-induced
hippocampal memory deficits through BLA activity-dependent p25 generation.
acknowledgement: |-
AG047661; NIH; Schweizerische Nationalfonds zur Förderung der Wissenschaftlichen Forschung
NS051874; NIH; Schweizerische Nationalfonds zur Förderung der Wissenschaftlichen Forschung
SNSF; Schweizerische Nationalfonds zur Förderung der Wissenschaftlichen Forschung
author:
- first_name: Damien
full_name: Rei, Damien
last_name: Rei
- first_name: Xenos
full_name: Mason, Xenos
last_name: Mason
- first_name: Jinsoo
full_name: Seo, Jinsoo
last_name: Seo
- first_name: Johannes
full_name: Gräff, Johannes
last_name: Gräff
- first_name: Andrii
full_name: Rudenko, Andrii
last_name: Rudenko
- first_name: Jùn
full_name: Wang, Jùn
last_name: Wang
- first_name: Richard
full_name: Rueda, Richard
last_name: Rueda
- first_name: Sandra
full_name: Sandra Siegert
id: 36ACD32E-F248-11E8-B48F-1D18A9856A87
last_name: Siegert
orcid: 0000-0001-8635-0877
- first_name: Sukhee
full_name: Cho, Sukhee
last_name: Cho
- first_name: Rebecca
full_name: Canter, Rebecca G
last_name: Canter
- first_name: Alison
full_name: Mungenast, Alison E
last_name: Mungenast
- first_name: Karl
full_name: Deisseroth, Karl A
last_name: Deisseroth
- first_name: Lihuei
full_name: Tsai, Lihuei
last_name: Tsai
citation:
ama: Rei D, Mason X, Seo J, et al. Basolateral amygdala bidirectionally modulates
stress induced hippocampal learning and memory deficits through a p25/Cdk5-dependent
pathway. PNAS. 2015;112(23):7291-7296. doi:10.1073/pnas.1415845112
apa: Rei, D., Mason, X., Seo, J., Gräff, J., Rudenko, A., Wang, J., … Tsai, L. (2015).
Basolateral amygdala bidirectionally modulates stress induced hippocampal learning
and memory deficits through a p25/Cdk5-dependent pathway. PNAS. National
Academy of Sciences. https://doi.org/10.1073/pnas.1415845112
chicago: Rei, Damien, Xenos Mason, Jinsoo Seo, Johannes Gräff, Andrii Rudenko, Jùn
Wang, Richard Rueda, et al. “Basolateral Amygdala Bidirectionally Modulates Stress
Induced Hippocampal Learning and Memory Deficits through a P25/Cdk5-Dependent
Pathway.” PNAS. National Academy of Sciences, 2015. https://doi.org/10.1073/pnas.1415845112.
ieee: D. Rei et al., “Basolateral amygdala bidirectionally modulates stress
induced hippocampal learning and memory deficits through a p25/Cdk5-dependent
pathway,” PNAS, vol. 112, no. 23. National Academy of Sciences, pp. 7291–7296,
2015.
ista: Rei D, Mason X, Seo J, Gräff J, Rudenko A, Wang J, Rueda R, Siegert S, Cho
S, Canter R, Mungenast A, Deisseroth K, Tsai L. 2015. Basolateral amygdala bidirectionally
modulates stress induced hippocampal learning and memory deficits through a p25/Cdk5-dependent
pathway. PNAS. 112(23), 7291–7296.
mla: Rei, Damien, et al. “Basolateral Amygdala Bidirectionally Modulates Stress
Induced Hippocampal Learning and Memory Deficits through a P25/Cdk5-Dependent
Pathway.” PNAS, vol. 112, no. 23, National Academy of Sciences, 2015, pp.
7291–96, doi:10.1073/pnas.1415845112.
short: D. Rei, X. Mason, J. Seo, J. Gräff, A. Rudenko, J. Wang, R. Rueda, S. Siegert,
S. Cho, R. Canter, A. Mungenast, K. Deisseroth, L. Tsai, PNAS 112 (2015) 7291–7296.
date_created: 2018-12-11T11:54:06Z
date_published: 2015-06-09T00:00:00Z
date_updated: 2021-01-12T06:53:18Z
day: '09'
doi: 10.1073/pnas.1415845112
extern: 1
intvolume: ' 112'
issue: '23'
month: '06'
page: 7291 - 7296
publication: PNAS
publication_status: published
publisher: National Academy of Sciences
publist_id: '5307'
quality_controlled: 0
status: public
title: Basolateral amygdala bidirectionally modulates stress induced hippocampal learning
and memory deficits through a p25/Cdk5-dependent pathway
type: journal_article
volume: 112
year: '2015'
...
---
_id: '1807'
abstract:
- lang: eng
text: We study a double Cahn-Hilliard type functional related to the Gross-Pitaevskii
energy of two-components Bose-Einstein condensates. In the case of large but same
order intercomponent and intracomponent coupling strengths, we prove Γ-convergence
to a perimeter minimisation functional with an inhomogeneous surface tension.
We study the asymptotic behavior of the surface tension as the ratio between the
intercomponent and intracomponent coupling strengths becomes very small or very
large and obtain good agreement with the physical literature. We obtain as a consequence,
symmetry breaking of the minimisers for the harmonic potential.
author:
- first_name: Michael
full_name: Goldman, Michael
last_name: Goldman
- first_name: Jimena
full_name: Royo-Letelier, Jimena
id: 4D3BED28-F248-11E8-B48F-1D18A9856A87
last_name: Royo-Letelier
citation:
ama: Goldman M, Royo-Letelier J. Sharp interface limit for two components Bose-Einstein
condensates. ESAIM - Control, Optimisation and Calculus of Variations.
2015;21(3):603-624. doi:10.1051/cocv/2014040
apa: Goldman, M., & Royo-Letelier, J. (2015). Sharp interface limit for two
components Bose-Einstein condensates. ESAIM - Control, Optimisation and Calculus
of Variations. EDP Sciences. https://doi.org/10.1051/cocv/2014040
chicago: Goldman, Michael, and Jimena Royo-Letelier. “Sharp Interface Limit for
Two Components Bose-Einstein Condensates.” ESAIM - Control, Optimisation and
Calculus of Variations. EDP Sciences, 2015. https://doi.org/10.1051/cocv/2014040.
ieee: M. Goldman and J. Royo-Letelier, “Sharp interface limit for two components
Bose-Einstein condensates,” ESAIM - Control, Optimisation and Calculus of Variations,
vol. 21, no. 3. EDP Sciences, pp. 603–624, 2015.
ista: Goldman M, Royo-Letelier J. 2015. Sharp interface limit for two components
Bose-Einstein condensates. ESAIM - Control, Optimisation and Calculus of Variations.
21(3), 603–624.
mla: Goldman, Michael, and Jimena Royo-Letelier. “Sharp Interface Limit for Two
Components Bose-Einstein Condensates.” ESAIM - Control, Optimisation and Calculus
of Variations, vol. 21, no. 3, EDP Sciences, 2015, pp. 603–24, doi:10.1051/cocv/2014040.
short: M. Goldman, J. Royo-Letelier, ESAIM - Control, Optimisation and Calculus
of Variations 21 (2015) 603–624.
date_created: 2018-12-11T11:54:07Z
date_published: 2015-05-01T00:00:00Z
date_updated: 2021-01-12T06:53:20Z
day: '01'
department:
- _id: RoSe
doi: 10.1051/cocv/2014040
intvolume: ' 21'
issue: '3'
language:
- iso: eng
main_file_link:
- open_access: '1'
url: http://arxiv.org/abs/1401.1727
month: '05'
oa: 1
oa_version: Preprint
page: 603 - 624
publication: ESAIM - Control, Optimisation and Calculus of Variations
publication_status: published
publisher: EDP Sciences
publist_id: '5303'
quality_controlled: '1'
scopus_import: 1
status: public
title: Sharp interface limit for two components Bose-Einstein condensates
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 21
year: '2015'
...
---
_id: '1802'
abstract:
- lang: eng
text: Noncoding variants in the human MIR137 gene locus increase schizophrenia risk
with genome-wide significance. However, the functional consequence of these risk
alleles is unknown. Here we examined induced human neurons harboring the minor
alleles of four disease-associated single nucleotide polymorphisms in MIR137.
We observed increased MIR137 levels compared to those in major allele–carrying
cells. microRNA-137 gain of function caused downregulation of the presynaptic
target genes complexin-1 (Cplx1), Nsf and synaptotagmin-1 (Syt1), leading to impaired
vesicle release. In vivo, miR-137 gain of function resulted in changes in synaptic
vesicle pool distribution, impaired induction of mossy fiber long-term potentiation
and deficits in hippocampus-dependent learning and memory. By sequestering endogenous
miR-137, we were able to ameliorate the synaptic phenotypes. Moreover, reinstatement
of Syt1 expression partially restored synaptic plasticity, demonstrating the importance
of Syt1 as a miR-137 target. Our data provide new insight into the mechanism by
which miR-137 dysregulation can impair synaptic plasticity in the hippocampus.
acknowledgement: S.S. was supported by a Human Frontier Science Program (HFSP) long-term
postdoctoral fellowship and a Swiss National Science Foundation fellowship for prospective
researchers. E.J.K. was supported by a Simons Foundation Postdoctoral Fellowship.
A.R. was supported by a NARSAD Young Investigator Award. This work was supported
by a Seed Grant from the Simons Center for the Social Brain and US National Institutes
of Health grant RO1 MH 091115 to L.-H.T.
author:
- first_name: Sandra
full_name: Sandra Siegert
id: 36ACD32E-F248-11E8-B48F-1D18A9856A87
last_name: Siegert
orcid: 0000-0001-8635-0877
- first_name: Jinsoo
full_name: Seo, Jinsoo
last_name: Seo
- first_name: Ester
full_name: Kwon, Ester J
last_name: Kwon
- first_name: Andrii
full_name: Rudenko, Andrii
last_name: Rudenko
- first_name: Sukhee
full_name: Cho, Sukhee
last_name: Cho
- first_name: Wenyuan
full_name: Wang, Wenyuan
last_name: Wang
- first_name: Zachary
full_name: Flood, Zachary C
last_name: Flood
- first_name: Anthony
full_name: Martorell, Anthony J
last_name: Martorell
- first_name: Maria
full_name: Ericsson, Maria
last_name: Ericsson
- first_name: Alison
full_name: Mungenast, Alison E
last_name: Mungenast
- first_name: Lihuei
full_name: Tsai, Lihuei
last_name: Tsai
citation:
ama: Siegert S, Seo J, Kwon E, et al. The schizophrenia risk gene product miR-137
alters presynaptic plasticity. Nature Neuroscience. 2015;18:1008-1016.
doi:10.1038/nn.4023
apa: Siegert, S., Seo, J., Kwon, E., Rudenko, A., Cho, S., Wang, W., … Tsai, L.
(2015). The schizophrenia risk gene product miR-137 alters presynaptic plasticity.
Nature Neuroscience. Nature Publishing Group. https://doi.org/10.1038/nn.4023
chicago: Siegert, Sandra, Jinsoo Seo, Ester Kwon, Andrii Rudenko, Sukhee Cho, Wenyuan
Wang, Zachary Flood, et al. “The Schizophrenia Risk Gene Product MiR-137 Alters
Presynaptic Plasticity.” Nature Neuroscience. Nature Publishing Group,
2015. https://doi.org/10.1038/nn.4023.
ieee: S. Siegert et al., “The schizophrenia risk gene product miR-137 alters
presynaptic plasticity,” Nature Neuroscience, vol. 18. Nature Publishing
Group, pp. 1008–1016, 2015.
ista: Siegert S, Seo J, Kwon E, Rudenko A, Cho S, Wang W, Flood Z, Martorell A,
Ericsson M, Mungenast A, Tsai L. 2015. The schizophrenia risk gene product miR-137
alters presynaptic plasticity. Nature Neuroscience. 18, 1008–1016.
mla: Siegert, Sandra, et al. “The Schizophrenia Risk Gene Product MiR-137 Alters
Presynaptic Plasticity.” Nature Neuroscience, vol. 18, Nature Publishing
Group, 2015, pp. 1008–16, doi:10.1038/nn.4023.
short: S. Siegert, J. Seo, E. Kwon, A. Rudenko, S. Cho, W. Wang, Z. Flood, A. Martorell,
M. Ericsson, A. Mungenast, L. Tsai, Nature Neuroscience 18 (2015) 1008–1016.
date_created: 2018-12-11T11:54:05Z
date_published: 2015-07-01T00:00:00Z
date_updated: 2021-01-12T06:53:18Z
day: '01'
doi: 10.1038/nn.4023
extern: 1
intvolume: ' 18'
month: '07'
page: 1008 - 1016
publication: Nature Neuroscience
publication_status: published
publisher: Nature Publishing Group
publist_id: '5308'
quality_controlled: 0
status: public
title: The schizophrenia risk gene product miR-137 alters presynaptic plasticity
type: journal_article
volume: 18
year: '2015'
...
---
_id: '1810'
abstract:
- lang: eng
text: Combining antibiotics is a promising strategy for increasing treatment efficacy
and for controlling resistance evolution. When drugs are combined, their effects
on cells may be amplified or weakened, that is the drugs may show synergistic
or antagonistic interactions. Recent work revealed the underlying mechanisms of
such drug interactions by elucidating the drugs'; joint effects on cell physiology.
Moreover, new treatment strategies that use drug combinations to exploit evolutionary
tradeoffs were shown to affect the rate of resistance evolution in predictable
ways. High throughput studies have further identified drug candidates based on
their interactions with established antibiotics and general principles that enable
the prediction of drug interactions were suggested. Overall, the conceptual and
technical foundation for the rational design of potent drug combinations is rapidly
developing.
author:
- first_name: Mark Tobias
full_name: Bollenbach, Mark Tobias
id: 3E6DB97A-F248-11E8-B48F-1D18A9856A87
last_name: Bollenbach
orcid: 0000-0003-4398-476X
citation:
ama: 'Bollenbach MT. Antimicrobial interactions: Mechanisms and implications for
drug discovery and resistance evolution. Current Opinion in Microbiology.
2015;27:1-9. doi:10.1016/j.mib.2015.05.008'
apa: 'Bollenbach, M. T. (2015). Antimicrobial interactions: Mechanisms and implications
for drug discovery and resistance evolution. Current Opinion in Microbiology.
Elsevier. https://doi.org/10.1016/j.mib.2015.05.008'
chicago: 'Bollenbach, Mark Tobias. “Antimicrobial Interactions: Mechanisms and Implications
for Drug Discovery and Resistance Evolution.” Current Opinion in Microbiology.
Elsevier, 2015. https://doi.org/10.1016/j.mib.2015.05.008.'
ieee: 'M. T. Bollenbach, “Antimicrobial interactions: Mechanisms and implications
for drug discovery and resistance evolution,” Current Opinion in Microbiology,
vol. 27. Elsevier, pp. 1–9, 2015.'
ista: 'Bollenbach MT. 2015. Antimicrobial interactions: Mechanisms and implications
for drug discovery and resistance evolution. Current Opinion in Microbiology.
27, 1–9.'
mla: 'Bollenbach, Mark Tobias. “Antimicrobial Interactions: Mechanisms and Implications
for Drug Discovery and Resistance Evolution.” Current Opinion in Microbiology,
vol. 27, Elsevier, 2015, pp. 1–9, doi:10.1016/j.mib.2015.05.008.'
short: M.T. Bollenbach, Current Opinion in Microbiology 27 (2015) 1–9.
date_created: 2018-12-11T11:54:08Z
date_published: 2015-06-01T00:00:00Z
date_updated: 2021-01-12T06:53:21Z
day: '01'
ddc:
- '570'
department:
- _id: ToBo
doi: 10.1016/j.mib.2015.05.008
ec_funded: 1
file:
- access_level: open_access
checksum: 1683bb0f42ef892a5b3b71a050d65d25
content_type: application/pdf
creator: system
date_created: 2018-12-12T10:17:23Z
date_updated: 2020-07-14T12:45:17Z
file_id: '5277'
file_name: IST-2016-493-v1+1_1-s2.0-S1369527415000594-main.pdf
file_size: 1047255
relation: main_file
file_date_updated: 2020-07-14T12:45:17Z
has_accepted_license: '1'
intvolume: ' 27'
language:
- iso: eng
month: '06'
oa: 1
oa_version: Published Version
page: 1 - 9
project:
- _id: 25E9AF9E-B435-11E9-9278-68D0E5697425
call_identifier: FWF
grant_number: P27201-B22
name: Revealing the mechanisms underlying drug interactions
- _id: 25E83C2C-B435-11E9-9278-68D0E5697425
call_identifier: FP7
grant_number: '303507'
name: Optimality principles in responses to antibiotics
- _id: 25EB3A80-B435-11E9-9278-68D0E5697425
grant_number: RGP0042/2013
name: Revealing the fundamental limits of cell growth
publication: Current Opinion in Microbiology
publication_status: published
publisher: Elsevier
publist_id: '5298'
pubrep_id: '493'
quality_controlled: '1'
scopus_import: 1
status: public
title: 'Antimicrobial interactions: Mechanisms and implications for drug discovery
and resistance evolution'
tmp:
image: /images/cc_by.png
legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
short: CC BY (4.0)
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 27
year: '2015'
...
---
_id: '1812'
abstract:
- lang: eng
text: "We investigate the occurrence of rotons in a quadrupolar Bose–Einstein condensate
confined to two dimensions. Depending on the particle density, the ratio of the
contact and quadrupole–quadrupole interactions, and the alignment of the quadrupole
moments with respect to the confinement plane, the dispersion relation features
two or four point-like roton minima or one ring-shaped minimum. We map out the
entire parameter space of the roton behavior and identify the instability regions.
We propose to observe the exotic rotons by monitoring the characteristic density
wave dynamics resulting from a short local perturbation, and discuss the possibilities
to detect the predicted effects in state-of-the-art experiments with ultracold
homonuclear molecules.\r\n"
article_number: '045005'
article_processing_charge: No
author:
- first_name: Martin
full_name: Lahrz, Martin
last_name: Lahrz
- first_name: Mikhail
full_name: Lemeshko, Mikhail
id: 37CB05FA-F248-11E8-B48F-1D18A9856A87
last_name: Lemeshko
orcid: 0000-0002-6990-7802
- first_name: Ludwig
full_name: Mathey, Ludwig
last_name: Mathey
citation:
ama: Lahrz M, Lemeshko M, Mathey L. Exotic roton excitations in quadrupolar Bose–Einstein
condensates . New Journal of Physics. 2015;17(4). doi:10.1088/1367-2630/17/4/045005
apa: Lahrz, M., Lemeshko, M., & Mathey, L. (2015). Exotic roton excitations
in quadrupolar Bose–Einstein condensates . New Journal of Physics. IOP
Publishing Ltd. https://doi.org/10.1088/1367-2630/17/4/045005
chicago: Lahrz, Martin, Mikhail Lemeshko, and Ludwig Mathey. “Exotic Roton Excitations
in Quadrupolar Bose–Einstein Condensates .” New Journal of Physics. IOP
Publishing Ltd., 2015. https://doi.org/10.1088/1367-2630/17/4/045005.
ieee: M. Lahrz, M. Lemeshko, and L. Mathey, “Exotic roton excitations in quadrupolar
Bose–Einstein condensates ,” New Journal of Physics, vol. 17, no. 4. IOP
Publishing Ltd., 2015.
ista: Lahrz M, Lemeshko M, Mathey L. 2015. Exotic roton excitations in quadrupolar
Bose–Einstein condensates . New Journal of Physics. 17(4), 045005.
mla: Lahrz, Martin, et al. “Exotic Roton Excitations in Quadrupolar Bose–Einstein
Condensates .” New Journal of Physics, vol. 17, no. 4, 045005, IOP Publishing
Ltd., 2015, doi:10.1088/1367-2630/17/4/045005.
short: M. Lahrz, M. Lemeshko, L. Mathey, New Journal of Physics 17 (2015).
date_created: 2018-12-11T11:54:09Z
date_published: 2015-04-01T00:00:00Z
date_updated: 2021-01-12T06:53:22Z
day: '01'
ddc:
- '530'
department:
- _id: MiLe
doi: 10.1088/1367-2630/17/4/045005
file:
- access_level: open_access
checksum: 551f751a75b39b89a1db2f7f498f9a49
content_type: application/pdf
creator: system
date_created: 2018-12-12T10:15:59Z
date_updated: 2020-07-14T12:45:17Z
file_id: '5184'
file_name: IST-2016-446-v1+1_document.pdf
file_size: 1900925
relation: main_file
file_date_updated: 2020-07-14T12:45:17Z
has_accepted_license: '1'
intvolume: ' 17'
issue: '4'
language:
- iso: eng
month: '04'
oa: 1
oa_version: Published Version
publication: New Journal of Physics
publication_status: published
publisher: IOP Publishing Ltd.
publist_id: '5294'
pubrep_id: '446'
quality_controlled: '1'
scopus_import: 1
status: public
title: 'Exotic roton excitations in quadrupolar Bose–Einstein condensates '
tmp:
image: /images/cc_by.png
legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
short: CC BY (4.0)
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 17
year: '2015'
...
---
_id: '1811'
abstract:
- lang: eng
text: Atomic form factors are widely used for the characterization of targets and
specimens, from crystallography to biology. By using recent mathematical results,
here we derive an analytical expression for the atomic form factor within the
independent particle model constructed from nonrelativistic screened hydrogenic
wave functions. The range of validity of this analytical expression is checked
by comparing the analytically obtained form factors with the ones obtained within
the Hartee-Fock method. As an example, we apply our analytical expression for
the atomic form factor to evaluate the differential cross section for Rayleigh
scattering off neutral atoms.
acknowledgement: The research leading to these results has received funding from the
People Programme (Marie Curie Actions) of the European Union’s Seventh Framework
Programme (FP7/2007-2013) under REA grant agreement n◦ [291734]. F.F. acknowledges
support by Fundação de Amparo à Pesquisa do estado de Minas Gerais (FAPEMIG), by
Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq), and by the
Austrian Science Fund (FWF) through the START Grant No. Y 591-N16.
article_number: '052105'
author:
- first_name: Laleh
full_name: Safari, Laleh
id: 3C325E5E-F248-11E8-B48F-1D18A9856A87
last_name: Safari
- first_name: José
full_name: Santos, José
last_name: Santos
- first_name: Pedro
full_name: Amaro, Pedro
last_name: Amaro
- first_name: Kari
full_name: Jänkälä, Kari
last_name: Jänkälä
- first_name: Filippo
full_name: Fratini, Filippo
last_name: Fratini
citation:
ama: 'Safari L, Santos J, Amaro P, Jänkälä K, Fratini F. Analytical evaluation of
atomic form factors: Application to Rayleigh scattering. Journal of Mathematical
Physics. 2015;56(5). doi:10.1063/1.4921227'
apa: 'Safari, L., Santos, J., Amaro, P., Jänkälä, K., & Fratini, F. (2015).
Analytical evaluation of atomic form factors: Application to Rayleigh scattering.
Journal of Mathematical Physics. American Institute of Physics. https://doi.org/10.1063/1.4921227'
chicago: 'Safari, Laleh, José Santos, Pedro Amaro, Kari Jänkälä, and Filippo Fratini.
“Analytical Evaluation of Atomic Form Factors: Application to Rayleigh Scattering.”
Journal of Mathematical Physics. American Institute of Physics, 2015. https://doi.org/10.1063/1.4921227.'
ieee: 'L. Safari, J. Santos, P. Amaro, K. Jänkälä, and F. Fratini, “Analytical evaluation
of atomic form factors: Application to Rayleigh scattering,” Journal of Mathematical
Physics, vol. 56, no. 5. American Institute of Physics, 2015.'
ista: 'Safari L, Santos J, Amaro P, Jänkälä K, Fratini F. 2015. Analytical evaluation
of atomic form factors: Application to Rayleigh scattering. Journal of Mathematical
Physics. 56(5), 052105.'
mla: 'Safari, Laleh, et al. “Analytical Evaluation of Atomic Form Factors: Application
to Rayleigh Scattering.” Journal of Mathematical Physics, vol. 56, no.
5, 052105, American Institute of Physics, 2015, doi:10.1063/1.4921227.'
short: L. Safari, J. Santos, P. Amaro, K. Jänkälä, F. Fratini, Journal of Mathematical
Physics 56 (2015).
date_created: 2018-12-11T11:54:08Z
date_published: 2015-05-20T00:00:00Z
date_updated: 2021-01-12T06:53:21Z
day: '20'
department:
- _id: MiLe
doi: 10.1063/1.4921227
ec_funded: 1
intvolume: ' 56'
issue: '5'
language:
- iso: eng
main_file_link:
- open_access: '1'
url: http://arxiv.org/abs/1409.0110
month: '05'
oa: 1
oa_version: Preprint
project:
- _id: 25681D80-B435-11E9-9278-68D0E5697425
call_identifier: FP7
grant_number: '291734'
name: International IST Postdoc Fellowship Programme
publication: Journal of Mathematical Physics
publication_status: published
publisher: American Institute of Physics
publist_id: '5295'
scopus_import: 1
status: public
title: 'Analytical evaluation of atomic form factors: Application to Rayleigh scattering'
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 56
year: '2015'
...
---
_id: '1813'
abstract:
- lang: eng
text: We develop a microscopic theory describing a quantum impurity whose rotational
degree of freedom is coupled to a many-particle bath. We approach the problem
by introducing the concept of an “angulon”—a quantum rotor dressed by a quantum
field—and reveal its quasiparticle properties using a combination of variational
and diagrammatic techniques. Our theory predicts renormalization of the impurity
rotational structure, such as that observed in experiments with molecules in superfluid
helium droplets, in terms of a rotational Lamb shift induced by the many-particle
environment. Furthermore, we discover a rich many-body-induced fine structure,
emerging in rotational spectra due to a redistribution of angular momentum within
the quantum many-body system.
article_number: '203001'
author:
- first_name: Richard
full_name: Schmidt, Richard
last_name: Schmidt
- first_name: Mikhail
full_name: Lemeshko, Mikhail
id: 37CB05FA-F248-11E8-B48F-1D18A9856A87
last_name: Lemeshko
orcid: 0000-0002-6990-7802
citation:
ama: Schmidt R, Lemeshko M. Rotation of quantum impurities in the presence of a
many-body environment. Physical Review Letters. 2015;114(20). doi:10.1103/PhysRevLett.114.203001
apa: Schmidt, R., & Lemeshko, M. (2015). Rotation of quantum impurities in the
presence of a many-body environment. Physical Review Letters. American
Physical Society. https://doi.org/10.1103/PhysRevLett.114.203001
chicago: Schmidt, Richard, and Mikhail Lemeshko. “Rotation of Quantum Impurities
in the Presence of a Many-Body Environment.” Physical Review Letters. American
Physical Society, 2015. https://doi.org/10.1103/PhysRevLett.114.203001.
ieee: R. Schmidt and M. Lemeshko, “Rotation of quantum impurities in the presence
of a many-body environment,” Physical Review Letters, vol. 114, no. 20.
American Physical Society, 2015.
ista: Schmidt R, Lemeshko M. 2015. Rotation of quantum impurities in the presence
of a many-body environment. Physical Review Letters. 114(20), 203001.
mla: Schmidt, Richard, and Mikhail Lemeshko. “Rotation of Quantum Impurities in
the Presence of a Many-Body Environment.” Physical Review Letters, vol.
114, no. 20, 203001, American Physical Society, 2015, doi:10.1103/PhysRevLett.114.203001.
short: R. Schmidt, M. Lemeshko, Physical Review Letters 114 (2015).
date_created: 2018-12-11T11:54:09Z
date_published: 2015-05-18T00:00:00Z
date_updated: 2021-01-12T06:53:22Z
day: '18'
department:
- _id: MiLe
doi: 10.1103/PhysRevLett.114.203001
intvolume: ' 114'
issue: '20'
language:
- iso: eng
main_file_link:
- open_access: '1'
url: http://arxiv.org/abs/1502.03447
month: '05'
oa: 1
oa_version: Preprint
publication: Physical Review Letters
publication_status: published
publisher: American Physical Society
publist_id: '5293'
quality_controlled: '1'
scopus_import: 1
status: public
title: Rotation of quantum impurities in the presence of a many-body environment
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 114
year: '2015'
...
---
_id: '1808'
article_number: '7'
author:
- first_name: Ashutosh
full_name: Gupta, Ashutosh
id: 335E5684-F248-11E8-B48F-1D18A9856A87
last_name: Gupta
- first_name: Thomas A
full_name: Henzinger, Thomas A
id: 40876CD8-F248-11E8-B48F-1D18A9856A87
last_name: Henzinger
orcid: 0000−0002−2985−7724
citation:
ama: Gupta A, Henzinger TA. Guest editors’ introduction to special issue on computational
methods in systems biology. ACM Transactions on Modeling and Computer Simulation.
2015;25(2). doi:10.1145/2745799
apa: Gupta, A., & Henzinger, T. A. (2015). Guest editors’ introduction to special
issue on computational methods in systems biology. ACM Transactions on Modeling
and Computer Simulation. ACM. https://doi.org/10.1145/2745799
chicago: Gupta, Ashutosh, and Thomas A Henzinger. “Guest Editors’ Introduction to
Special Issue on Computational Methods in Systems Biology.” ACM Transactions
on Modeling and Computer Simulation. ACM, 2015. https://doi.org/10.1145/2745799.
ieee: A. Gupta and T. A. Henzinger, “Guest editors’ introduction to special issue
on computational methods in systems biology,” ACM Transactions on Modeling
and Computer Simulation, vol. 25, no. 2. ACM, 2015.
ista: Gupta A, Henzinger TA. 2015. Guest editors’ introduction to special issue
on computational methods in systems biology. ACM Transactions on Modeling and
Computer Simulation. 25(2), 7.
mla: Gupta, Ashutosh, and Thomas A. Henzinger. “Guest Editors’ Introduction to Special
Issue on Computational Methods in Systems Biology.” ACM Transactions on Modeling
and Computer Simulation, vol. 25, no. 2, 7, ACM, 2015, doi:10.1145/2745799.
short: A. Gupta, T.A. Henzinger, ACM Transactions on Modeling and Computer Simulation
25 (2015).
date_created: 2018-12-11T11:54:07Z
date_published: 2015-05-01T00:00:00Z
date_updated: 2021-01-12T06:53:20Z
day: '01'
department:
- _id: ToHe
doi: 10.1145/2745799
intvolume: ' 25'
issue: '2'
language:
- iso: eng
month: '05'
oa_version: None
publication: ACM Transactions on Modeling and Computer Simulation
publication_status: published
publisher: ACM
publist_id: '5302'
quality_controlled: '1'
status: public
title: Guest editors' introduction to special issue on computational methods in systems
biology
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 25
year: '2015'
...
---
_id: '1817'
abstract:
- lang: eng
text: 'Vertebrates have a unique 3D body shape in which correct tissue and organ
shape and alignment are essential for function. For example, vision requires the
lens to be centred in the eye cup which must in turn be correctly positioned in
the head. Tissue morphogenesis depends on force generation, force transmission
through the tissue, and response of tissues and extracellular matrix to force.
Although a century ago D''Arcy Thompson postulated that terrestrial animal body
shapes are conditioned by gravity, there has been no animal model directly demonstrating
how the aforementioned mechano-morphogenetic processes are coordinated to generate
a body shape that withstands gravity. Here we report a unique medaka fish (Oryzias
latipes) mutant, hirame (hir), which is sensitive to deformation by gravity. hir
embryos display a markedly flattened body caused by mutation of YAP, a nuclear
executor of Hippo signalling that regulates organ size. We show that actomyosin-mediated
tissue tension is reduced in hir embryos, leading to tissue flattening and tissue
misalignment, both of which contribute to body flattening. By analysing YAP function
in 3D spheroids of human cells, we identify the Rho GTPase activating protein
ARHGAP18 as an effector of YAP in controlling tissue tension. Together, these
findings reveal a previously unrecognised function of YAP in regulating tissue
shape and alignment required for proper 3D body shape. Understanding this morphogenetic
function of YAP could facilitate the use of embryonic stem cells to generate complex
organs requiring correct alignment of multiple tissues. '
author:
- first_name: Sean
full_name: Porazinski, Sean
last_name: Porazinski
- first_name: Huijia
full_name: Wang, Huijia
last_name: Wang
- first_name: Yoichi
full_name: Asaoka, Yoichi
last_name: Asaoka
- first_name: Martin
full_name: Behrndt, Martin
id: 3ECECA3A-F248-11E8-B48F-1D18A9856A87
last_name: Behrndt
- first_name: Tatsuo
full_name: Miyamoto, Tatsuo
last_name: Miyamoto
- first_name: Hitoshi
full_name: Morita, Hitoshi
id: 4C6E54C6-F248-11E8-B48F-1D18A9856A87
last_name: Morita
- first_name: Shoji
full_name: Hata, Shoji
last_name: Hata
- first_name: Takashi
full_name: Sasaki, Takashi
last_name: Sasaki
- first_name: Gabriel
full_name: Krens, Gabriel
id: 2B819732-F248-11E8-B48F-1D18A9856A87
last_name: Krens
orcid: 0000-0003-4761-5996
- first_name: Yumi
full_name: Osada, Yumi
last_name: Osada
- first_name: Satoshi
full_name: Asaka, Satoshi
last_name: Asaka
- first_name: Akihiro
full_name: Momoi, Akihiro
last_name: Momoi
- first_name: Sarah
full_name: Linton, Sarah
last_name: Linton
- first_name: Joel
full_name: Miesfeld, Joel
last_name: Miesfeld
- first_name: Brian
full_name: Link, Brian
last_name: Link
- first_name: Takeshi
full_name: Senga, Takeshi
last_name: Senga
- first_name: Atahualpa
full_name: Castillo Morales, Atahualpa
last_name: Castillo Morales
- first_name: Araxi
full_name: Urrutia, Araxi
last_name: Urrutia
- first_name: Nobuyoshi
full_name: Shimizu, Nobuyoshi
last_name: Shimizu
- first_name: Hideaki
full_name: Nagase, Hideaki
last_name: Nagase
- first_name: Shinya
full_name: Matsuura, Shinya
last_name: Matsuura
- first_name: Stefan
full_name: Bagby, Stefan
last_name: Bagby
- first_name: Hisato
full_name: Kondoh, Hisato
last_name: Kondoh
- first_name: Hiroshi
full_name: Nishina, Hiroshi
last_name: Nishina
- first_name: Carl-Philipp J
full_name: Heisenberg, Carl-Philipp J
id: 39427864-F248-11E8-B48F-1D18A9856A87
last_name: Heisenberg
orcid: 0000-0002-0912-4566
- first_name: Makoto
full_name: Furutani Seiki, Makoto
last_name: Furutani Seiki
citation:
ama: Porazinski S, Wang H, Asaoka Y, et al. YAP is essential for tissue tension
to ensure vertebrate 3D body shape. Nature. 2015;521(7551):217-221. doi:10.1038/nature14215
apa: Porazinski, S., Wang, H., Asaoka, Y., Behrndt, M., Miyamoto, T., Morita, H.,
… Furutani Seiki, M. (2015). YAP is essential for tissue tension to ensure vertebrate
3D body shape. Nature. Nature Publishing Group. https://doi.org/10.1038/nature14215
chicago: Porazinski, Sean, Huijia Wang, Yoichi Asaoka, Martin Behrndt, Tatsuo Miyamoto,
Hitoshi Morita, Shoji Hata, et al. “YAP Is Essential for Tissue Tension to Ensure
Vertebrate 3D Body Shape.” Nature. Nature Publishing Group, 2015. https://doi.org/10.1038/nature14215.
ieee: S. Porazinski et al., “YAP is essential for tissue tension to ensure
vertebrate 3D body shape,” Nature, vol. 521, no. 7551. Nature Publishing
Group, pp. 217–221, 2015.
ista: Porazinski S, Wang H, Asaoka Y, Behrndt M, Miyamoto T, Morita H, Hata S, Sasaki
T, Krens G, Osada Y, Asaka S, Momoi A, Linton S, Miesfeld J, Link B, Senga T,
Castillo Morales A, Urrutia A, Shimizu N, Nagase H, Matsuura S, Bagby S, Kondoh
H, Nishina H, Heisenberg C-PJ, Furutani Seiki M. 2015. YAP is essential for tissue
tension to ensure vertebrate 3D body shape. Nature. 521(7551), 217–221.
mla: Porazinski, Sean, et al. “YAP Is Essential for Tissue Tension to Ensure Vertebrate
3D Body Shape.” Nature, vol. 521, no. 7551, Nature Publishing Group, 2015,
pp. 217–21, doi:10.1038/nature14215.
short: S. Porazinski, H. Wang, Y. Asaoka, M. Behrndt, T. Miyamoto, H. Morita, S.
Hata, T. Sasaki, G. Krens, Y. Osada, S. Asaka, A. Momoi, S. Linton, J. Miesfeld,
B. Link, T. Senga, A. Castillo Morales, A. Urrutia, N. Shimizu, H. Nagase, S.
Matsuura, S. Bagby, H. Kondoh, H. Nishina, C.-P.J. Heisenberg, M. Furutani Seiki,
Nature 521 (2015) 217–221.
date_created: 2018-12-11T11:54:10Z
date_published: 2015-03-16T00:00:00Z
date_updated: 2021-01-12T06:53:23Z
day: '16'
department:
- _id: CaHe
doi: 10.1038/nature14215
external_id:
pmid:
- '25778702'
intvolume: ' 521'
issue: '7551'
language:
- iso: eng
main_file_link:
- open_access: '1'
url: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4720436/
month: '03'
oa: 1
oa_version: Submitted Version
page: 217 - 221
pmid: 1
publication: Nature
publication_status: published
publisher: Nature Publishing Group
publist_id: '5289'
quality_controlled: '1'
scopus_import: 1
status: public
title: YAP is essential for tissue tension to ensure vertebrate 3D body shape
type: journal_article
user_id: 2EBD1598-F248-11E8-B48F-1D18A9856A87
volume: 521
year: '2015'
...
---
_id: '1820'
abstract:
- lang: eng
text: 'We consider partially observable Markov decision processes (POMDPs) with
a set of target states and every transition is associated with an integer cost.
The optimization objec- tive we study asks to minimize the expected total cost
till the target set is reached, while ensuring that the target set is reached
almost-surely (with probability 1). We show that for integer costs approximating
the optimal cost is undecidable. For positive costs, our results are as follows:
(i) we establish matching lower and upper bounds for the optimal cost and the
bound is double exponential; (ii) we show that the problem of approximating the
optimal cost is decidable and present ap- proximation algorithms developing on
the existing algorithms for POMDPs with finite-horizon objectives. While the worst-
case running time of our algorithm is double exponential, we present efficient
stopping criteria for the algorithm and show experimentally that it performs well
in many examples.'
acknowledgement: ' The research was partly supported by Austrian Science Fund (FWF)
Grant No P23499-N23, FWF NFN Grant No S11407-N23 (RiSE), ERC Start grant (279307:
Graph Games), and Microsoft faculty fellows award.'
alternative_title:
- Artifical Intelligence
author:
- first_name: Krishnendu
full_name: Chatterjee, Krishnendu
id: 2E5DCA20-F248-11E8-B48F-1D18A9856A87
last_name: Chatterjee
orcid: 0000-0002-4561-241X
- first_name: Martin
full_name: Chmelik, Martin
id: 3624234E-F248-11E8-B48F-1D18A9856A87
last_name: Chmelik
- first_name: Raghav
full_name: Gupta, Raghav
last_name: Gupta
- first_name: Ayush
full_name: Kanodia, Ayush
last_name: Kanodia
citation:
ama: 'Chatterjee K, Chmelik M, Gupta R, Kanodia A. Optimal cost almost-sure reachability
in POMDPs. In: Proceedings of the Twenty-Ninth AAAI Conference on Artificial
Intelligence . Vol 5. AAAI Press; 2015:3496-3502.'
apa: 'Chatterjee, K., Chmelik, M., Gupta, R., & Kanodia, A. (2015). Optimal
cost almost-sure reachability in POMDPs. In Proceedings of the Twenty-Ninth
AAAI Conference on Artificial Intelligence (Vol. 5, pp. 3496–3502). Austin,
TX, USA: AAAI Press.'
chicago: Chatterjee, Krishnendu, Martin Chmelik, Raghav Gupta, and Ayush Kanodia.
“Optimal Cost Almost-Sure Reachability in POMDPs.” In Proceedings of the Twenty-Ninth
AAAI Conference on Artificial Intelligence , 5:3496–3502. AAAI Press, 2015.
ieee: K. Chatterjee, M. Chmelik, R. Gupta, and A. Kanodia, “Optimal cost almost-sure
reachability in POMDPs,” in Proceedings of the Twenty-Ninth AAAI Conference
on Artificial Intelligence , Austin, TX, USA, 2015, vol. 5, pp. 3496–3502.
ista: 'Chatterjee K, Chmelik M, Gupta R, Kanodia A. 2015. Optimal cost almost-sure
reachability in POMDPs. Proceedings of the Twenty-Ninth AAAI Conference on Artificial
Intelligence . IAAI: Innovative Applications of Artificial Intelligence, Artifical
Intelligence, vol. 5, 3496–3502.'
mla: Chatterjee, Krishnendu, et al. “Optimal Cost Almost-Sure Reachability in POMDPs.”
Proceedings of the Twenty-Ninth AAAI Conference on Artificial Intelligence
, vol. 5, AAAI Press, 2015, pp. 3496–502.
short: K. Chatterjee, M. Chmelik, R. Gupta, A. Kanodia, in:, Proceedings of the
Twenty-Ninth AAAI Conference on Artificial Intelligence , AAAI Press, 2015, pp.
3496–3502.
conference:
end_date: 2015-01-30
location: Austin, TX, USA
name: 'IAAI: Innovative Applications of Artificial Intelligence'
start_date: 2015-01-25
date_created: 2018-12-11T11:54:11Z
date_published: 2015-06-01T00:00:00Z
date_updated: 2023-02-23T10:02:57Z
day: '01'
department:
- _id: KrCh
ec_funded: 1
external_id:
arxiv:
- '1411.3880'
intvolume: ' 5'
language:
- iso: eng
main_file_link:
- open_access: '1'
url: http://arxiv.org/abs/1411.3880
month: '06'
oa: 1
oa_version: Preprint
page: 3496-3502
project:
- _id: 2584A770-B435-11E9-9278-68D0E5697425
call_identifier: FWF
grant_number: P 23499-N23
name: Modern Graph Algorithmic Techniques in Formal Verification
- _id: 25832EC2-B435-11E9-9278-68D0E5697425
call_identifier: FWF
grant_number: S 11407_N23
name: Rigorous Systems Engineering
- _id: 2581B60A-B435-11E9-9278-68D0E5697425
call_identifier: FP7
grant_number: '279307'
name: 'Quantitative Graph Games: Theory and Applications'
publication: 'Proceedings of the Twenty-Ninth AAAI Conference on Artificial Intelligence '
publication_status: published
publisher: AAAI Press
publist_id: '5286'
quality_controlled: '1'
related_material:
record:
- id: '1529'
relation: later_version
status: public
scopus_import: 1
status: public
title: Optimal cost almost-sure reachability in POMDPs
type: conference
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 5
year: '2015'
...
---
_id: '1814'
abstract:
- lang: eng
text: 'We present an efficient wavefront tracking algorithm for animating bodies
of water that interact with their environment. Our contributions include: a novel
wavefront tracking technique that enables dispersion, refraction, reflection,
and diffraction in the same simulation; a unique multivalued function interpolation
method that enables our simulations to elegantly sidestep the Nyquist limit; a
dispersion approximation for efficiently amplifying the number of simulated waves
by several orders of magnitude; and additional extensions that allow for time-dependent
effects and interactive artistic editing of the resulting animation. Our contributions
combine to give us multitudes more wave details than similar algorithms, while
maintaining high frame rates and allowing close camera zooms.'
article_number: '27'
author:
- first_name: Stefan
full_name: Jeschke, Stefan
id: 44D6411A-F248-11E8-B48F-1D18A9856A87
last_name: Jeschke
- first_name: Christopher J
full_name: Wojtan, Christopher J
id: 3C61F1D2-F248-11E8-B48F-1D18A9856A87
last_name: Wojtan
orcid: 0000-0001-6646-5546
citation:
ama: Jeschke S, Wojtan C. Water wave animation via wavefront parameter interpolation.
ACM Transactions on Graphics. 2015;34(3). doi:10.1145/2714572
apa: Jeschke, S., & Wojtan, C. (2015). Water wave animation via wavefront parameter
interpolation. ACM Transactions on Graphics. ACM. https://doi.org/10.1145/2714572
chicago: Jeschke, Stefan, and Chris Wojtan. “Water Wave Animation via Wavefront
Parameter Interpolation.” ACM Transactions on Graphics. ACM, 2015. https://doi.org/10.1145/2714572.
ieee: S. Jeschke and C. Wojtan, “Water wave animation via wavefront parameter interpolation,”
ACM Transactions on Graphics, vol. 34, no. 3. ACM, 2015.
ista: Jeschke S, Wojtan C. 2015. Water wave animation via wavefront parameter interpolation.
ACM Transactions on Graphics. 34(3), 27.
mla: Jeschke, Stefan, and Chris Wojtan. “Water Wave Animation via Wavefront Parameter
Interpolation.” ACM Transactions on Graphics, vol. 34, no. 3, 27, ACM,
2015, doi:10.1145/2714572.
short: S. Jeschke, C. Wojtan, ACM Transactions on Graphics 34 (2015).
date_created: 2018-12-11T11:54:09Z
date_published: 2015-04-01T00:00:00Z
date_updated: 2023-02-23T10:15:40Z
day: '01'
ddc:
- '000'
department:
- _id: ChWo
doi: 10.1145/2714572
ec_funded: 1
file:
- access_level: open_access
checksum: 67c9f4fa370def68cdf31299e48bc91f
content_type: application/pdf
creator: system
date_created: 2018-12-12T10:12:15Z
date_updated: 2020-07-14T12:45:17Z
file_id: '4933'
file_name: IST-2016-575-v1+1_wavefront_preprint.pdf
file_size: 23712153
relation: main_file
file_date_updated: 2020-07-14T12:45:17Z
has_accepted_license: '1'
intvolume: ' 34'
issue: '3'
language:
- iso: eng
month: '04'
oa: 1
oa_version: Submitted Version
project:
- _id: 25357BD2-B435-11E9-9278-68D0E5697425
call_identifier: FWF
grant_number: P 24352-N23
name: 'Deep Pictures: Creating Visual and Haptic Vector Images'
- _id: 2533E772-B435-11E9-9278-68D0E5697425
call_identifier: H2020
grant_number: '638176'
name: Efficient Simulation of Natural Phenomena at Extremely Large Scales
publication: ACM Transactions on Graphics
publication_status: published
publisher: ACM
publist_id: '5292'
pubrep_id: '575'
quality_controlled: '1'
scopus_import: 1
status: public
title: Water wave animation via wavefront parameter interpolation
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 34
year: '2015'
...
---
_id: '1818'
abstract:
- lang: eng
text: 'Why do species not adapt to ever-wider ranges of conditions, gradually expanding
their ecological niche and geographic range? Gene flow across environments has
two conflicting effects: although it increases genetic variation, which is a prerequisite
for adaptation, gene flow may swamp adaptation to local conditions. In 1956, Haldane
proposed that, when the environment varies across space, "swamping"
by gene flow creates a positive feedback between low population size and maladaptation,
leading to a sharp range margin. However, current deterministic theory shows that,
when variance can evolve, there is no such limit. Using simple analytical tools
and simulations, we show that genetic drift can generate a sharp margin to a species''
range, by reducing genetic variance below the level needed for adaptation to spatially
variable conditions. Aided by separation of ecological and evolutionary timescales,
the identified effective dimensionless parameters reveal a simple threshold that
predicts when adaptation at the range margin fails. Two observable parameters
determine the threshold: (i) the effective environmental gradient, which can be
measured by the loss of fitness due to dispersal to a different environment; and
(ii) the efficacy of selection relative to genetic drift. The theory predicts
sharp range margins even in the absence of abrupt changes in the environment.
Furthermore, it implies that gradual worsening of conditions across a species''
habitat may lead to a sudden range fragmentation, when adaptation to a wide span
of conditions within a single species becomes impossible.'
author:
- first_name: Jitka
full_name: Polechova, Jitka
id: 3BBFB084-F248-11E8-B48F-1D18A9856A87
last_name: Polechova
orcid: 0000-0003-0951-3112
- first_name: Nicholas H
full_name: Barton, Nicholas H
id: 4880FE40-F248-11E8-B48F-1D18A9856A87
last_name: Barton
orcid: 0000-0002-8548-5240
citation:
ama: Polechova J, Barton NH. Limits to adaptation along environmental gradients.
PNAS. 2015;112(20):6401-6406. doi:10.1073/pnas.1421515112
apa: Polechova, J., & Barton, N. H. (2015). Limits to adaptation along environmental
gradients. PNAS. National Academy of Sciences. https://doi.org/10.1073/pnas.1421515112
chicago: Polechova, Jitka, and Nicholas H Barton. “Limits to Adaptation along Environmental
Gradients.” PNAS. National Academy of Sciences, 2015. https://doi.org/10.1073/pnas.1421515112.
ieee: J. Polechova and N. H. Barton, “Limits to adaptation along environmental gradients,”
PNAS, vol. 112, no. 20. National Academy of Sciences, pp. 6401–6406, 2015.
ista: Polechova J, Barton NH. 2015. Limits to adaptation along environmental gradients.
PNAS. 112(20), 6401–6406.
mla: Polechova, Jitka, and Nicholas H. Barton. “Limits to Adaptation along Environmental
Gradients.” PNAS, vol. 112, no. 20, National Academy of Sciences, 2015,
pp. 6401–06, doi:10.1073/pnas.1421515112.
short: J. Polechova, N.H. Barton, PNAS 112 (2015) 6401–6406.
date_created: 2018-12-11T11:54:11Z
date_published: 2015-05-19T00:00:00Z
date_updated: 2021-01-12T06:53:24Z
day: '19'
department:
- _id: NiBa
doi: 10.1073/pnas.1421515112
ec_funded: 1
external_id:
pmid:
- '25941385'
intvolume: ' 112'
issue: '20'
language:
- iso: eng
main_file_link:
- open_access: '1'
url: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4443383/
month: '05'
oa: 1
oa_version: Submitted Version
page: 6401 - 6406
pmid: 1
project:
- _id: 25B07788-B435-11E9-9278-68D0E5697425
call_identifier: FP7
grant_number: '250152'
name: Limits to selection in biology and in evolutionary computation
publication: PNAS
publication_status: published
publisher: National Academy of Sciences
publist_id: '5288'
quality_controlled: '1'
scopus_import: 1
status: public
title: Limits to adaptation along environmental gradients
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 112
year: '2015'
...
---
_id: '1819'
abstract:
- lang: eng
text: 'The sessile life style of plants creates the need to deal with an often adverse
environment, in which water availability can change on a daily basis, challenging
the cellular physiology and integrity. Changes in osmotic conditions disrupt the
equilibrium of the plasma membrane: hypoosmotic conditions increase and hyperosmotic
environment decrease the cell volume. Here, we show that short-term extracellular
osmotic treatments are closely followed by a shift in the balance between endocytosis
and exocytosis in root meristem cells. Acute hyperosmotic treatments (ionic and
nonionic) enhance clathrin-mediated endocytosis simultaneously attenuating exocytosis,
whereas hypoosmotic treatments have the opposite effects. In addition to clathrin
recruitment to the plasma membrane, components of early endocytic trafficking
are essential during hyperosmotic stress responses. Consequently, growth of seedlings
defective in elements of clathrin or early endocytic machinery is more sensitive
to hyperosmotic treatments. We also found that the endocytotic response to a change
of osmotic status in the environment is dominant over the presumably evolutionary
more recent regulatory effect of plant hormones, such as auxin. These results
imply that osmotic perturbation influences the balance between endocytosis and
exocytosis acting through clathrin-mediated endocytosis. We propose that tension
on the plasma membrane determines the addition or removal of membranes at the
cell surface, thus preserving cell integrity.'
acknowledgement: This work was supported by the European Research Council (project
ERC-2011-StG-20101109-PSDP); European Social Fund (CZ.1.07/2.3.00/20.0043) and the
Czech Science Foundation GAČR (GA13-40637S) to J.F.; project Postdoc I. (CZ.1.07/2.3.00/30.0009)
co-financed by the European Social Fund and the state budget of the Czech Republic
to M.Z. and T.N..
author:
- first_name: Marta
full_name: Zwiewka, Marta
last_name: Zwiewka
- first_name: Tomasz
full_name: Nodzyński, Tomasz
last_name: Nodzyński
- first_name: Stéphanie
full_name: Robert, Stéphanie
last_name: Robert
- first_name: Steffen
full_name: Vanneste, Steffen
last_name: Vanneste
- first_name: Jiřĺ
full_name: Friml, Jiřĺ
id: 4159519E-F248-11E8-B48F-1D18A9856A87
last_name: Friml
orcid: 0000-0002-8302-7596
citation:
ama: Zwiewka M, Nodzyński T, Robert S, Vanneste S, Friml J. Osmotic stress modulates
the balance between exocytosis and clathrin mediated endocytosis in Arabidopsis
thaliana. Molecular Plant. 2015;8(8):1175-1187. doi:10.1016/j.molp.2015.03.007
apa: Zwiewka, M., Nodzyński, T., Robert, S., Vanneste, S., & Friml, J. (2015).
Osmotic stress modulates the balance between exocytosis and clathrin mediated
endocytosis in Arabidopsis thaliana. Molecular Plant. Elsevier. https://doi.org/10.1016/j.molp.2015.03.007
chicago: Zwiewka, Marta, Tomasz Nodzyński, Stéphanie Robert, Steffen Vanneste, and
Jiří Friml. “Osmotic Stress Modulates the Balance between Exocytosis and Clathrin
Mediated Endocytosis in Arabidopsis Thaliana.” Molecular Plant. Elsevier,
2015. https://doi.org/10.1016/j.molp.2015.03.007.
ieee: M. Zwiewka, T. Nodzyński, S. Robert, S. Vanneste, and J. Friml, “Osmotic stress
modulates the balance between exocytosis and clathrin mediated endocytosis in
Arabidopsis thaliana,” Molecular Plant, vol. 8, no. 8. Elsevier, pp. 1175–1187,
2015.
ista: Zwiewka M, Nodzyński T, Robert S, Vanneste S, Friml J. 2015. Osmotic stress
modulates the balance between exocytosis and clathrin mediated endocytosis in
Arabidopsis thaliana. Molecular Plant. 8(8), 1175–1187.
mla: Zwiewka, Marta, et al. “Osmotic Stress Modulates the Balance between Exocytosis
and Clathrin Mediated Endocytosis in Arabidopsis Thaliana.” Molecular Plant,
vol. 8, no. 8, Elsevier, 2015, pp. 1175–87, doi:10.1016/j.molp.2015.03.007.
short: M. Zwiewka, T. Nodzyński, S. Robert, S. Vanneste, J. Friml, Molecular Plant
8 (2015) 1175–1187.
date_created: 2018-12-11T11:54:11Z
date_published: 2015-08-03T00:00:00Z
date_updated: 2021-01-12T06:53:24Z
day: '03'
department:
- _id: JiFr
doi: 10.1016/j.molp.2015.03.007
ec_funded: 1
intvolume: ' 8'
issue: '8'
language:
- iso: eng
month: '08'
oa_version: None
page: 1175 - 1187
project:
- _id: 25716A02-B435-11E9-9278-68D0E5697425
call_identifier: FP7
grant_number: '282300'
name: Polarity and subcellular dynamics in plants
publication: Molecular Plant
publication_status: published
publisher: Elsevier
publist_id: '5287'
quality_controlled: '1'
scopus_import: 1
status: public
title: Osmotic stress modulates the balance between exocytosis and clathrin mediated
endocytosis in Arabidopsis thaliana
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 8
year: '2015'
...
---
_id: '1823'
abstract:
- lang: eng
text: Abstract Drug combinations are increasingly important in disease treatments,
for combating drug resistance, and for elucidating fundamental relationships in
cell physiology. When drugs are combined, their individual effects on cells may
be amplified or weakened. Such drug interactions are crucial for treatment efficacy,
but their underlying mechanisms remain largely unknown. To uncover the causes
of drug interactions, we developed a systematic approach based on precise quantification
of the individual and joint effects of antibiotics on growth of genome-wide Escherichia
coli gene deletion strains. We found that drug interactions between antibiotics
representing the main modes of action are highly robust to genetic perturbation.
This robustness is encapsulated in a general principle of bacterial growth, which
enables the quantitative prediction of mutant growth rates under drug combinations.
Rare violations of this principle exposed recurring cellular functions controlling
drug interactions. In particular, we found that polysaccharide and ATP synthesis
control multiple drug interactions with previously unexplained mechanisms, and
small molecule adjuvants targeting these functions synthetically reshape drug
interactions in predictable ways. These results provide a new conceptual framework
for the design of multidrug combinations and suggest that there are universal
mechanisms at the heart of most drug interactions. Synopsis A general principle
of bacterial growth enables the prediction of mutant growth rates under drug combinations.
Rare violations of this principle expose cellular functions that control drug
interactions and can be targeted by small molecules to alter drug interactions
in predictable ways. Drug interactions between antibiotics are highly robust to
genetic perturbations. A general principle of bacterial growth enables the prediction
of mutant growth rates under drug combinations. Rare violations of this principle
expose cellular functions that control drug interactions. Diverse drug interactions
are controlled by recurring cellular functions, including LPS synthesis and ATP
synthesis. A general principle of bacterial growth enables the prediction of mutant
growth rates under drug combinations. Rare violations of this principle expose
cellular functions that control drug interactions and can be targeted by small
molecules to alter drug interactions in predictable ways.
article_number: '807'
author:
- first_name: Guillaume
full_name: Chevereau, Guillaume
id: 424D78A0-F248-11E8-B48F-1D18A9856A87
last_name: Chevereau
- first_name: Mark Tobias
full_name: Bollenbach, Mark Tobias
id: 3E6DB97A-F248-11E8-B48F-1D18A9856A87
last_name: Bollenbach
orcid: 0000-0003-4398-476X
citation:
ama: Chevereau G, Bollenbach MT. Systematic discovery of drug interaction mechanisms.
Molecular Systems Biology. 2015;11(4). doi:10.15252/msb.20156098
apa: Chevereau, G., & Bollenbach, M. T. (2015). Systematic discovery of drug
interaction mechanisms. Molecular Systems Biology. Nature Publishing Group.
https://doi.org/10.15252/msb.20156098
chicago: Chevereau, Guillaume, and Mark Tobias Bollenbach. “Systematic Discovery
of Drug Interaction Mechanisms.” Molecular Systems Biology. Nature Publishing
Group, 2015. https://doi.org/10.15252/msb.20156098.
ieee: G. Chevereau and M. T. Bollenbach, “Systematic discovery of drug interaction
mechanisms,” Molecular Systems Biology, vol. 11, no. 4. Nature Publishing
Group, 2015.
ista: Chevereau G, Bollenbach MT. 2015. Systematic discovery of drug interaction
mechanisms. Molecular Systems Biology. 11(4), 807.
mla: Chevereau, Guillaume, and Mark Tobias Bollenbach. “Systematic Discovery of
Drug Interaction Mechanisms.” Molecular Systems Biology, vol. 11, no. 4,
807, Nature Publishing Group, 2015, doi:10.15252/msb.20156098.
short: G. Chevereau, M.T. Bollenbach, Molecular Systems Biology 11 (2015).
date_created: 2018-12-11T11:54:12Z
date_published: 2015-04-01T00:00:00Z
date_updated: 2021-01-12T06:53:26Z
day: '01'
ddc:
- '570'
department:
- _id: ToBo
doi: 10.15252/msb.20156098
ec_funded: 1
file:
- access_level: open_access
checksum: 4289b518fbe2166682fb1a1ef9b405f3
content_type: application/pdf
creator: system
date_created: 2018-12-12T10:14:34Z
date_updated: 2020-07-14T12:45:17Z
file_id: '5087'
file_name: IST-2015-395-v1+1_807.full.pdf
file_size: 1273573
relation: main_file
file_date_updated: 2020-07-14T12:45:17Z
has_accepted_license: '1'
intvolume: ' 11'
issue: '4'
language:
- iso: eng
month: '04'
oa: 1
oa_version: Published Version
project:
- _id: 25E9AF9E-B435-11E9-9278-68D0E5697425
call_identifier: FWF
grant_number: P27201-B22
name: Revealing the mechanisms underlying drug interactions
- _id: 25EB3A80-B435-11E9-9278-68D0E5697425
grant_number: RGP0042/2013
name: Revealing the fundamental limits of cell growth
- _id: 25E83C2C-B435-11E9-9278-68D0E5697425
call_identifier: FP7
grant_number: '303507'
name: Optimality principles in responses to antibiotics
publication: Molecular Systems Biology
publication_status: published
publisher: Nature Publishing Group
publist_id: '5283'
pubrep_id: '395'
quality_controlled: '1'
scopus_import: 1
status: public
title: Systematic discovery of drug interaction mechanisms
tmp:
image: /images/cc_by.png
legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
short: CC BY (4.0)
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 11
year: '2015'
...
---
_id: '1824'
abstract:
- lang: eng
text: Condensation phenomena arise through a collective behaviour of particles.
They are observed in both classical and quantum systems, ranging from the formation
of traffic jams in mass transport models to the macroscopic occupation of the
energetic ground state in ultra-cold bosonic gases (Bose-Einstein condensation).
Recently, it has been shown that a driven and dissipative system of bosons may
form multiple condensates. Which states become the condensates has, however, remained
elusive thus far. The dynamics of this condensation are described by coupled birth-death
processes, which also occur in evolutionary game theory. Here we apply concepts
from evolutionary game theory to explain the formation of multiple condensates
in such driven-dissipative bosonic systems. We show that the vanishing of relative
entropy production determines their selection. The condensation proceeds exponentially
fast, but the system never comes to rest. Instead, the occupation numbers of condensates
may oscillate, as we demonstrate for a rock-paper-scissors game of condensates.
article_number: '6977'
author:
- first_name: Johannes
full_name: Knebel, Johannes
last_name: Knebel
- first_name: Markus
full_name: Weber, Markus
last_name: Weber
- first_name: Torben H
full_name: Krüger, Torben H
id: 3020C786-F248-11E8-B48F-1D18A9856A87
last_name: Krüger
orcid: 0000-0002-4821-3297
- first_name: Erwin
full_name: Frey, Erwin
last_name: Frey
citation:
ama: Knebel J, Weber M, Krüger TH, Frey E. Evolutionary games of condensates in
coupled birth-death processes. Nature Communications. 2015;6. doi:10.1038/ncomms7977
apa: Knebel, J., Weber, M., Krüger, T. H., & Frey, E. (2015). Evolutionary games
of condensates in coupled birth-death processes. Nature Communications.
Nature Publishing Group. https://doi.org/10.1038/ncomms7977
chicago: Knebel, Johannes, Markus Weber, Torben H Krüger, and Erwin Frey. “Evolutionary
Games of Condensates in Coupled Birth-Death Processes.” Nature Communications.
Nature Publishing Group, 2015. https://doi.org/10.1038/ncomms7977.
ieee: J. Knebel, M. Weber, T. H. Krüger, and E. Frey, “Evolutionary games of condensates
in coupled birth-death processes,” Nature Communications, vol. 6. Nature
Publishing Group, 2015.
ista: Knebel J, Weber M, Krüger TH, Frey E. 2015. Evolutionary games of condensates
in coupled birth-death processes. Nature Communications. 6, 6977.
mla: Knebel, Johannes, et al. “Evolutionary Games of Condensates in Coupled Birth-Death
Processes.” Nature Communications, vol. 6, 6977, Nature Publishing Group,
2015, doi:10.1038/ncomms7977.
short: J. Knebel, M. Weber, T.H. Krüger, E. Frey, Nature Communications 6 (2015).
date_created: 2018-12-11T11:54:13Z
date_published: 2015-04-24T00:00:00Z
date_updated: 2021-01-12T06:53:26Z
day: '24'
ddc:
- '530'
department:
- _id: LaEr
doi: 10.1038/ncomms7977
file:
- access_level: open_access
checksum: c4cffb5c8b245e658a34eac71a03e7cc
content_type: application/pdf
creator: system
date_created: 2018-12-12T10:16:54Z
date_updated: 2020-07-14T12:45:17Z
file_id: '5245'
file_name: IST-2016-451-v1+1_ncomms7977.pdf
file_size: 1151501
relation: main_file
file_date_updated: 2020-07-14T12:45:17Z
has_accepted_license: '1'
intvolume: ' 6'
language:
- iso: eng
month: '04'
oa: 1
oa_version: Published Version
publication: Nature Communications
publication_status: published
publisher: Nature Publishing Group
publist_id: '5282'
pubrep_id: '451'
quality_controlled: '1'
scopus_import: 1
status: public
title: Evolutionary games of condensates in coupled birth-death processes
tmp:
image: /images/cc_by.png
legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
short: CC BY (4.0)
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 6
year: '2015'
...
---
_id: '1831'
abstract:
- lang: eng
text: This paper introduces a theme issue presenting the latest developments in
research on the impacts of sociality on health and fitness. The articles that
follow cover research on societies ranging from insects to humans. Variation in
measures of fitness (i.e. survival and reproduction) has been linked to various
aspects of sociality in humans and animals alike, and variability in individual
health and condition has been recognized as a key mediator of these relationships.
Viewed from a broad evolutionary perspective, the evolutionary transitions from
a solitary lifestyle to group living have resulted in several new health-related
costs and benefits of sociality. Social transmission of parasites within groups
represents a major cost of group living, but some behavioural mechanisms, such
as grooming, have evolved repeatedly to reduce this cost. Group living also has
created novel costs in terms of altered susceptibility to infectious and non-infectious
disease as a result of the unavoidable physiological consequences of social competition
and integration, which are partly alleviated by social buffering in some vertebrates.
Here, we define the relevant aspects of sociality, summarize their health-related
costs and benefits, and discuss possible fitness measures in different study systems.
Given the pervasive effects of social factors on health and fitness, we propose
a synthesis of existing conceptual approaches in disease ecology, ecological immunology
and behavioural neurosciences by adding sociality as a key factor, with the goal
to generate a broader framework for organismal integration of health-related research.
acknowledgement: We thank the German Research Foundation (DFG), the Ministry of Science
and Culture of Lower-Saxony (MWK Hannover) and the German Primate Centre (DPZ) for
their support of the 9. Göttinger Freilandtage in 2013, a conference at which most
contributions to this issue were first presented, the referees of the contributions
to this issue for their constructive comments, Meggan Craft for comments, and Helen
Eaton for her support in producing this theme issue.
article_number: '20140116'
author:
- first_name: Peter
full_name: Kappeler, Peter
last_name: Kappeler
- first_name: Sylvia
full_name: Cremer, Sylvia
id: 2F64EC8C-F248-11E8-B48F-1D18A9856A87
last_name: Cremer
orcid: 0000-0002-2193-3868
- first_name: Charles
full_name: Nunn, Charles
last_name: Nunn
citation:
ama: 'Kappeler P, Cremer S, Nunn C. Sociality and health: Impacts of sociality on
disease susceptibility and transmission in animal and human societies. Philosophical
Transactions of the Royal Society of London Series B, Biological Sciences.
2015;370(1669). doi:10.1098/rstb.2014.0116'
apa: 'Kappeler, P., Cremer, S., & Nunn, C. (2015). Sociality and health: Impacts
of sociality on disease susceptibility and transmission in animal and human societies.
Philosophical Transactions of the Royal Society of London. Series B, Biological
Sciences. Royal Society. https://doi.org/10.1098/rstb.2014.0116'
chicago: 'Kappeler, Peter, Sylvia Cremer, and Charles Nunn. “Sociality and Health:
Impacts of Sociality on Disease Susceptibility and Transmission in Animal and
Human Societies.” Philosophical Transactions of the Royal Society of London.
Series B, Biological Sciences. Royal Society, 2015. https://doi.org/10.1098/rstb.2014.0116.'
ieee: 'P. Kappeler, S. Cremer, and C. Nunn, “Sociality and health: Impacts of sociality
on disease susceptibility and transmission in animal and human societies,” Philosophical
Transactions of the Royal Society of London. Series B, Biological Sciences,
vol. 370, no. 1669. Royal Society, 2015.'
ista: 'Kappeler P, Cremer S, Nunn C. 2015. Sociality and health: Impacts of sociality
on disease susceptibility and transmission in animal and human societies. Philosophical
Transactions of the Royal Society of London. Series B, Biological Sciences. 370(1669),
20140116.'
mla: 'Kappeler, Peter, et al. “Sociality and Health: Impacts of Sociality on Disease
Susceptibility and Transmission in Animal and Human Societies.” Philosophical
Transactions of the Royal Society of London. Series B, Biological Sciences,
vol. 370, no. 1669, 20140116, Royal Society, 2015, doi:10.1098/rstb.2014.0116.'
short: P. Kappeler, S. Cremer, C. Nunn, Philosophical Transactions of the Royal
Society of London. Series B, Biological Sciences 370 (2015).
date_created: 2018-12-11T11:54:15Z
date_published: 2015-05-01T00:00:00Z
date_updated: 2021-01-12T06:53:29Z
day: '01'
department:
- _id: SyCr
doi: 10.1098/rstb.2014.0116
external_id:
pmid:
- '25870402'
intvolume: ' 370'
issue: '1669'
language:
- iso: eng
main_file_link:
- open_access: '1'
url: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4410382/
month: '05'
oa: 1
oa_version: Submitted Version
pmid: 1
publication: Philosophical Transactions of the Royal Society of London. Series B,
Biological Sciences
publication_status: published
publisher: Royal Society
publist_id: '5272'
quality_controlled: '1'
scopus_import: 1
status: public
title: 'Sociality and health: Impacts of sociality on disease susceptibility and transmission
in animal and human societies'
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 370
year: '2015'
...
---
_id: '1828'
abstract:
- lang: eng
text: We construct a non-linear Markov process connected with a biological model
of a bacterial genome recombination. The description of invariant measures of
this process gives us the solution of one problem in elementary probability theory.
article_processing_charge: No
author:
- first_name: Arseniy
full_name: Akopyan, Arseniy
id: 430D2C90-F248-11E8-B48F-1D18A9856A87
last_name: Akopyan
orcid: 0000-0002-2548-617X
- first_name: Sergey
full_name: Pirogov, Sergey
last_name: Pirogov
- first_name: Aleksandr
full_name: Rybko, Aleksandr
last_name: Rybko
citation:
ama: Akopyan A, Pirogov S, Rybko A. Invariant measures of genetic recombination
process. Journal of Statistical Physics. 2015;160(1):163-167. doi:10.1007/s10955-015-1238-5
apa: Akopyan, A., Pirogov, S., & Rybko, A. (2015). Invariant measures of genetic
recombination process. Journal of Statistical Physics. Springer. https://doi.org/10.1007/s10955-015-1238-5
chicago: Akopyan, Arseniy, Sergey Pirogov, and Aleksandr Rybko. “Invariant Measures
of Genetic Recombination Process.” Journal of Statistical Physics. Springer,
2015. https://doi.org/10.1007/s10955-015-1238-5.
ieee: A. Akopyan, S. Pirogov, and A. Rybko, “Invariant measures of genetic recombination
process,” Journal of Statistical Physics, vol. 160, no. 1. Springer, pp.
163–167, 2015.
ista: Akopyan A, Pirogov S, Rybko A. 2015. Invariant measures of genetic recombination
process. Journal of Statistical Physics. 160(1), 163–167.
mla: Akopyan, Arseniy, et al. “Invariant Measures of Genetic Recombination Process.”
Journal of Statistical Physics, vol. 160, no. 1, Springer, 2015, pp. 163–67,
doi:10.1007/s10955-015-1238-5.
short: A. Akopyan, S. Pirogov, A. Rybko, Journal of Statistical Physics 160 (2015)
163–167.
date_created: 2018-12-11T11:54:14Z
date_published: 2015-07-01T00:00:00Z
date_updated: 2021-01-12T06:53:28Z
day: '01'
department:
- _id: HeEd
doi: 10.1007/s10955-015-1238-5
ec_funded: 1
intvolume: ' 160'
issue: '1'
language:
- iso: eng
main_file_link:
- open_access: '1'
url: arxiv.org/abs/1406.5313
month: '07'
oa: 1
oa_version: Preprint
page: 163 - 167
project:
- _id: 25681D80-B435-11E9-9278-68D0E5697425
call_identifier: FP7
grant_number: '291734'
name: International IST Postdoc Fellowship Programme
publication: Journal of Statistical Physics
publication_status: published
publisher: Springer
publist_id: '5276'
quality_controlled: '1'
scopus_import: 1
status: public
title: Invariant measures of genetic recombination process
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 160
year: '2015'
...
---
_id: '1836'
abstract:
- lang: eng
text: In the standard framework for worst-case execution time (WCET) analysis of
programs, the main data structure is a single instance of integer linear programming
(ILP) that represents the whole program. The instance of this NP-hard problem
must be solved to find an estimate forWCET, and it must be refined if the estimate
is not tight.We propose a new framework for WCET analysis, based on abstract segment
trees (ASTs) as the main data structure. The ASTs have two advantages. First,
they allow computing WCET by solving a number of independent small ILP instances.
Second, ASTs store more expressive constraints, thus enabling a more efficient
and precise refinement procedure. In order to realize our framework algorithmically,
we develop an algorithm for WCET estimation on ASTs, and we develop an interpolation-based
counterexample-guided refinement scheme for ASTs. Furthermore, we extend our framework
to obtain parametric estimates of WCET. We experimentally evaluate our approach
on a set of examples from WCET benchmark suites and linear-algebra packages. We
show that our analysis, with comparable effort, provides WCET estimates that in
many cases significantly improve those computed by existing tools.
alternative_title:
- LNCS
author:
- first_name: Pavol
full_name: Cerny, Pavol
id: 4DCBEFFE-F248-11E8-B48F-1D18A9856A87
last_name: Cerny
- first_name: Thomas A
full_name: Henzinger, Thomas A
id: 40876CD8-F248-11E8-B48F-1D18A9856A87
last_name: Henzinger
orcid: 0000−0002−2985−7724
- first_name: Laura
full_name: Kovács, Laura
last_name: Kovács
- first_name: Arjun
full_name: Radhakrishna, Arjun
id: 3B51CAC4-F248-11E8-B48F-1D18A9856A87
last_name: Radhakrishna
- first_name: Jakob
full_name: Zwirchmayr, Jakob
last_name: Zwirchmayr
citation:
ama: Cerny P, Henzinger TA, Kovács L, Radhakrishna A, Zwirchmayr J. Segment abstraction
for worst-case execution time analysis. 2015;9032:105-131. doi:10.1007/978-3-662-46669-8_5
apa: 'Cerny, P., Henzinger, T. A., Kovács, L., Radhakrishna, A., & Zwirchmayr,
J. (2015). Segment abstraction for worst-case execution time analysis. Presented
at the ESOP: European Symposium on Programming, London, United Kingdom: Springer.
https://doi.org/10.1007/978-3-662-46669-8_5'
chicago: Cerny, Pavol, Thomas A Henzinger, Laura Kovács, Arjun Radhakrishna, and
Jakob Zwirchmayr. “Segment Abstraction for Worst-Case Execution Time Analysis.”
Lecture Notes in Computer Science. Springer, 2015. https://doi.org/10.1007/978-3-662-46669-8_5.
ieee: P. Cerny, T. A. Henzinger, L. Kovács, A. Radhakrishna, and J. Zwirchmayr,
“Segment abstraction for worst-case execution time analysis,” vol. 9032. Springer,
pp. 105–131, 2015.
ista: Cerny P, Henzinger TA, Kovács L, Radhakrishna A, Zwirchmayr J. 2015. Segment
abstraction for worst-case execution time analysis. 9032, 105–131.
mla: Cerny, Pavol, et al. Segment Abstraction for Worst-Case Execution Time Analysis.
Vol. 9032, Springer, 2015, pp. 105–31, doi:10.1007/978-3-662-46669-8_5.
short: P. Cerny, T.A. Henzinger, L. Kovács, A. Radhakrishna, J. Zwirchmayr, 9032
(2015) 105–131.
conference:
end_date: 2015-04-18
location: London, United Kingdom
name: 'ESOP: European Symposium on Programming'
start_date: 2015-04-11
date_created: 2018-12-11T11:54:16Z
date_published: 2015-04-01T00:00:00Z
date_updated: 2020-08-11T10:09:32Z
day: '01'
department:
- _id: ToHe
doi: 10.1007/978-3-662-46669-8_5
ec_funded: 1
intvolume: ' 9032'
language:
- iso: eng
month: '04'
oa_version: None
page: 105 - 131
project:
- _id: 25EE3708-B435-11E9-9278-68D0E5697425
call_identifier: FP7
grant_number: '267989'
name: Quantitative Reactive Modeling
- _id: 25832EC2-B435-11E9-9278-68D0E5697425
call_identifier: FWF
grant_number: S 11407_N23
name: Rigorous Systems Engineering
publication_status: published
publisher: Springer
publist_id: '5266'
quality_controlled: '1'
scopus_import: 1
series_title: Lecture Notes in Computer Science
status: public
title: Segment abstraction for worst-case execution time analysis
type: conference
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 9032
year: '2015'
...
---
_id: '1838'
abstract:
- lang: eng
text: Synthesis of program parts is particularly useful for concurrent systems.
However, most approaches do not support common design tasks, like modifying a
single process without having to re-synthesize or verify the whole system. Assume-guarantee
synthesis (AGS) provides robustness against modifications of system parts, but
thus far has been limited to the perfect information setting. This means that
local variables cannot be hidden from other processes, which renders synthesis
results cumbersome or even impossible to realize.We resolve this shortcoming by
defining AGS under partial information. We analyze the complexity and decidability
in different settings, showing that the problem has a high worstcase complexity
and is undecidable in many interesting cases. Based on these observations, we
present a pragmatic algorithm based on bounded synthesis, and demonstrate its
practical applicability on several examples.
acknowledgement: 'This work was supported by the Austrian Science Fund (FWF) through
the research network RiSE (S11406-N23, S11407-N23) and grant nr. P23499-N23, by
the European Commission through an ERC Start grant (279307: Graph Games) and project
STANCE (317753), as well as by the German Research Foundation (DFG) through SFB/TR
14 AVACS and project ASDPS(JA 2357/2-1).'
alternative_title:
- LNCS
author:
- first_name: Roderick
full_name: Bloem, Roderick
last_name: Bloem
- first_name: Krishnendu
full_name: Chatterjee, Krishnendu
id: 2E5DCA20-F248-11E8-B48F-1D18A9856A87
last_name: Chatterjee
orcid: 0000-0002-4561-241X
- first_name: Swen
full_name: Jacobs, Swen
last_name: Jacobs
- first_name: Robert
full_name: Könighofer, Robert
last_name: Könighofer
citation:
ama: 'Bloem R, Chatterjee K, Jacobs S, Könighofer R. Assume-guarantee synthesis
for concurrent reactive programs with partial information. In: Vol 9035. Springer;
2015:517-532. doi:10.1007/978-3-662-46681-0_50'
apa: 'Bloem, R., Chatterjee, K., Jacobs, S., & Könighofer, R. (2015). Assume-guarantee
synthesis for concurrent reactive programs with partial information (Vol. 9035,
pp. 517–532). Presented at the TACAS: Tools and Algorithms for the Construction
and Analysis of Systems, London, United Kingdom: Springer. https://doi.org/10.1007/978-3-662-46681-0_50'
chicago: Bloem, Roderick, Krishnendu Chatterjee, Swen Jacobs, and Robert Könighofer.
“Assume-Guarantee Synthesis for Concurrent Reactive Programs with Partial Information,”
9035:517–32. Springer, 2015. https://doi.org/10.1007/978-3-662-46681-0_50.
ieee: 'R. Bloem, K. Chatterjee, S. Jacobs, and R. Könighofer, “Assume-guarantee
synthesis for concurrent reactive programs with partial information,” presented
at the TACAS: Tools and Algorithms for the Construction and Analysis of Systems,
London, United Kingdom, 2015, vol. 9035, pp. 517–532.'
ista: 'Bloem R, Chatterjee K, Jacobs S, Könighofer R. 2015. Assume-guarantee synthesis
for concurrent reactive programs with partial information. TACAS: Tools and Algorithms
for the Construction and Analysis of Systems, LNCS, vol. 9035, 517–532.'
mla: Bloem, Roderick, et al. Assume-Guarantee Synthesis for Concurrent Reactive
Programs with Partial Information. Vol. 9035, Springer, 2015, pp. 517–32,
doi:10.1007/978-3-662-46681-0_50.
short: R. Bloem, K. Chatterjee, S. Jacobs, R. Könighofer, in:, Springer, 2015, pp.
517–532.
conference:
end_date: 2015-04-18
location: London, United Kingdom
name: 'TACAS: Tools and Algorithms for the Construction and Analysis of Systems'
start_date: 2015-04-11
date_created: 2018-12-11T11:54:17Z
date_published: 2015-01-01T00:00:00Z
date_updated: 2021-01-12T06:53:32Z
day: '01'
department:
- _id: KrCh
doi: 10.1007/978-3-662-46681-0_50
ec_funded: 1
intvolume: ' 9035'
language:
- iso: eng
main_file_link:
- open_access: '1'
url: http://arxiv.org/abs/1411.4604
month: '01'
oa: 1
oa_version: Preprint
page: 517 - 532
project:
- _id: 25832EC2-B435-11E9-9278-68D0E5697425
call_identifier: FWF
grant_number: S 11407_N23
name: Rigorous Systems Engineering
- _id: 2584A770-B435-11E9-9278-68D0E5697425
call_identifier: FWF
grant_number: P 23499-N23
name: Modern Graph Algorithmic Techniques in Formal Verification
- _id: 2581B60A-B435-11E9-9278-68D0E5697425
call_identifier: FP7
grant_number: '279307'
name: 'Quantitative Graph Games: Theory and Applications'
publication_status: published
publisher: Springer
publist_id: '5264'
scopus_import: 1
status: public
title: Assume-guarantee synthesis for concurrent reactive programs with partial information
type: conference
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 9035
year: '2015'
...
---
_id: '1839'
abstract:
- lang: eng
text: We present MultiGain, a tool to synthesize strategies for Markov decision
processes (MDPs) with multiple mean-payoff objectives. Our models are described
in PRISM, and our tool uses the existing interface and simulator of PRISM. Our
tool extends PRISM by adding novel algorithms for multiple mean-payoff objectives,
and also provides features such as (i) generating strategies and exploring them
for simulation, and checking them with respect to other properties; and (ii) generating
an approximate Pareto curve for two mean-payoff objectives. In addition, we present
a new practical algorithm for the analysis of MDPs with multiple mean-payoff objectives
under memoryless strategies.
alternative_title:
- LNCS
author:
- first_name: Tomáš
full_name: Brázdil, Tomáš
last_name: Brázdil
- first_name: Krishnendu
full_name: Chatterjee, Krishnendu
id: 2E5DCA20-F248-11E8-B48F-1D18A9856A87
last_name: Chatterjee
orcid: 0000-0002-4561-241X
- first_name: Vojtěch
full_name: Forejt, Vojtěch
last_name: Forejt
- first_name: Antonín
full_name: Kučera, Antonín
last_name: Kučera
citation:
ama: 'Brázdil T, Chatterjee K, Forejt V, Kučera A. Multigain: A controller synthesis
tool for MDPs with multiple mean-payoff objectives. 2015;9035:181-187. doi:10.1007/978-3-662-46681-0_12'
apa: 'Brázdil, T., Chatterjee, K., Forejt, V., & Kučera, A. (2015). Multigain:
A controller synthesis tool for MDPs with multiple mean-payoff objectives. Presented
at the TACAS: Tools and Algorithms for the Construction and Analysis of Systems,
London, United Kingdom: Springer. https://doi.org/10.1007/978-3-662-46681-0_12'
chicago: 'Brázdil, Tomáš, Krishnendu Chatterjee, Vojtěch Forejt, and Antonín Kučera.
“Multigain: A Controller Synthesis Tool for MDPs with Multiple Mean-Payoff Objectives.”
Lecture Notes in Computer Science. Springer, 2015. https://doi.org/10.1007/978-3-662-46681-0_12.'
ieee: 'T. Brázdil, K. Chatterjee, V. Forejt, and A. Kučera, “Multigain: A controller
synthesis tool for MDPs with multiple mean-payoff objectives,” vol. 9035. Springer,
pp. 181–187, 2015.'
ista: 'Brázdil T, Chatterjee K, Forejt V, Kučera A. 2015. Multigain: A controller
synthesis tool for MDPs with multiple mean-payoff objectives. 9035, 181–187.'
mla: 'Brázdil, Tomáš, et al. Multigain: A Controller Synthesis Tool for MDPs
with Multiple Mean-Payoff Objectives. Vol. 9035, Springer, 2015, pp. 181–87,
doi:10.1007/978-3-662-46681-0_12.'
short: T. Brázdil, K. Chatterjee, V. Forejt, A. Kučera, 9035 (2015) 181–187.
conference:
end_date: 2015-04-18
location: London, United Kingdom
name: 'TACAS: Tools and Algorithms for the Construction and Analysis of Systems'
start_date: 2015-04-11
date_created: 2018-12-11T11:54:18Z
date_published: 2015-01-01T00:00:00Z
date_updated: 2020-01-21T13:18:52Z
day: '01'
department:
- _id: KrCh
doi: 10.1007/978-3-662-46681-0_12
ec_funded: 1
intvolume: ' 9035'
language:
- iso: eng
main_file_link:
- open_access: '1'
url: http://arxiv.org/abs/1501.03093
month: '01'
oa: 1
oa_version: Preprint
page: 181 - 187
project:
- _id: 2584A770-B435-11E9-9278-68D0E5697425
call_identifier: FWF
grant_number: P 23499-N23
name: Modern Graph Algorithmic Techniques in Formal Verification
- _id: 25832EC2-B435-11E9-9278-68D0E5697425
call_identifier: FWF
grant_number: S 11407_N23
name: Rigorous Systems Engineering
- _id: 2581B60A-B435-11E9-9278-68D0E5697425
call_identifier: FP7
grant_number: '279307'
name: 'Quantitative Graph Games: Theory and Applications'
publication_status: published
publisher: Springer
publist_id: '5263'
quality_controlled: '1'
series_title: Lecture Notes in Computer Science
status: public
title: 'Multigain: A controller synthesis tool for MDPs with multiple mean-payoff
objectives'
type: conference
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 9035
year: '2015'
...
---
_id: '1837'
abstract:
- lang: eng
text: 'Transition to turbulence in straight pipes occurs in spite of the linear
stability of the laminar Hagen-Poiseuille flow if both the amplitude of flow perturbations
and the Reynolds number Re exceed a minimum threshold (subcritical transition).
As the pipe curvature increases, centrifugal effects become important, modifying
the basic flow as well as the most unstable linear modes. If the curvature (tube-to-coiling
diameter d/D) is sufficiently large, a Hopf bifurcation (supercritical instability)
is encountered before turbulence can be excited (subcritical instability). We
trace the instability thresholds in the Re - d/D parameter space in the range
0.01 ≤ d/D\ ≤ 0.1 by means of laser-Doppler velocimetry and determine the point
where the subcritical and supercritical instabilities meet. Two different experimental
set-ups are used: a closed system where the pipe forms an axisymmetric torus and
an open system employing a helical pipe. Implications for the measurement of friction
factors in curved pipes are discussed.'
article_number: R3
article_processing_charge: No
article_type: original
author:
- first_name: Jakob
full_name: Kühnen, Jakob
id: 3A47AE32-F248-11E8-B48F-1D18A9856A87
last_name: Kühnen
orcid: 0000-0003-4312-0179
- first_name: P
full_name: Braunshier, P
last_name: Braunshier
- first_name: M
full_name: Schwegel, M
last_name: Schwegel
- first_name: Hendrik
full_name: Kuhlmann, Hendrik
last_name: Kuhlmann
- first_name: Björn
full_name: Hof, Björn
id: 3A374330-F248-11E8-B48F-1D18A9856A87
last_name: Hof
orcid: 0000-0003-2057-2754
citation:
ama: Kühnen J, Braunshier P, Schwegel M, Kuhlmann H, Hof B. Subcritical versus supercritical
transition to turbulence in curved pipes. Journal of Fluid Mechanics. 2015;770(5).
doi:10.1017/jfm.2015.184
apa: Kühnen, J., Braunshier, P., Schwegel, M., Kuhlmann, H., & Hof, B. (2015).
Subcritical versus supercritical transition to turbulence in curved pipes. Journal
of Fluid Mechanics. Cambridge University Press. https://doi.org/10.1017/jfm.2015.184
chicago: Kühnen, Jakob, P Braunshier, M Schwegel, Hendrik Kuhlmann, and Björn Hof.
“Subcritical versus Supercritical Transition to Turbulence in Curved Pipes.” Journal
of Fluid Mechanics. Cambridge University Press, 2015. https://doi.org/10.1017/jfm.2015.184.
ieee: J. Kühnen, P. Braunshier, M. Schwegel, H. Kuhlmann, and B. Hof, “Subcritical
versus supercritical transition to turbulence in curved pipes,” Journal of
Fluid Mechanics, vol. 770, no. 5. Cambridge University Press, 2015.
ista: Kühnen J, Braunshier P, Schwegel M, Kuhlmann H, Hof B. 2015. Subcritical versus
supercritical transition to turbulence in curved pipes. Journal of Fluid Mechanics.
770(5), R3.
mla: Kühnen, Jakob, et al. “Subcritical versus Supercritical Transition to Turbulence
in Curved Pipes.” Journal of Fluid Mechanics, vol. 770, no. 5, R3, Cambridge
University Press, 2015, doi:10.1017/jfm.2015.184.
short: J. Kühnen, P. Braunshier, M. Schwegel, H. Kuhlmann, B. Hof, Journal of Fluid
Mechanics 770 (2015).
date_created: 2018-12-11T11:54:17Z
date_published: 2015-04-08T00:00:00Z
date_updated: 2021-01-12T06:53:31Z
day: '08'
department:
- _id: BjHo
doi: 10.1017/jfm.2015.184
ec_funded: 1
external_id:
arxiv:
- '1508.06559'
intvolume: ' 770'
issue: '5'
language:
- iso: eng
main_file_link:
- open_access: '1'
url: https://arxiv.org/abs/1508.06559
month: '04'
oa: 1
oa_version: Preprint
project:
- _id: 25152F3A-B435-11E9-9278-68D0E5697425
call_identifier: FP7
grant_number: '306589'
name: Decoding the complexity of turbulence at its origin
publication: Journal of Fluid Mechanics
publication_status: published
publisher: Cambridge University Press
publist_id: '5265'
quality_controlled: '1'
scopus_import: 1
status: public
title: Subcritical versus supercritical transition to turbulence in curved pipes
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 770
year: '2015'
...
---
_id: '1848'
abstract:
- lang: eng
text: The ability to escape apoptosis is a hallmark of cancer-initiating cells and
a key factor of resistance to oncolytic therapy. Here, we identify FAM96A as a
ubiquitous, evolutionarily conserved apoptosome-activating protein and investigate
its potential pro-apoptotic tumor suppressor function in gastrointestinal stromal
tumors (GISTs). Interaction between FAM96A and apoptotic peptidase activating
factor 1 (APAF1) was identified in yeast two-hybrid screen and further studied
by deletion mutants, glutathione-S-transferase pull-down, co-immunoprecipitation
and immunofluorescence. Effects of FAM96A overexpression and knock-down on apoptosis
sensitivity were examined in cancer cells and zebrafish embryos. Expression of
FAM96A in GISTs and histogenetically related cells including interstitial cells
of Cajal (ICCs), “fibroblast-like cells” (FLCs) and ICC stem cells (ICC-SCs) was
investigated by Northern blotting, reverse transcription—polymerase chain reaction,
immunohistochemistry and Western immunoblotting. Tumorigenicity of GIST cells
and transformed murine ICC-SCs stably transduced to re-express FAM96A was studied
by xeno- and allografting into immunocompromised mice. FAM96A was found to bind
APAF1 and to enhance the induction of mitochondrial apoptosis. FAM96A protein
or mRNA was dramatically reduced or lost in 106 of 108 GIST samples representing
three independent patient cohorts. Whereas ICCs, ICC-SCs and FLCs, the presumed
normal counterparts of GIST, were found to robustly express FAM96A protein and
mRNA, FAM96A expression was much reduced in tumorigenic ICC-SCs. Re-expression
of FAM96A in GIST cells and transformed ICC-SCs increased apoptosis sensitivity
and diminished tumorigenicity. Our data suggest FAM96A is a novel pro-apoptotic
tumor suppressor that is lost during GIST tumorigenesis.
article_processing_charge: No
article_type: original
author:
- first_name: Bettina
full_name: Schwamb, Bettina
last_name: Schwamb
- first_name: Robert
full_name: Pick, Robert
last_name: Pick
- first_name: Sara
full_name: Fernández, Sara
last_name: Fernández
- first_name: Kirsten
full_name: Völp, Kirsten
last_name: Völp
- first_name: Jan
full_name: Heering, Jan
last_name: Heering
- first_name: Volker
full_name: Dötsch, Volker
last_name: Dötsch
- first_name: Susanne
full_name: Bösser, Susanne
last_name: Bösser
- first_name: Jennifer
full_name: Jung, Jennifer
last_name: Jung
- first_name: Rasa
full_name: Beinoravičiute Kellner, Rasa
last_name: Beinoravičiute Kellner
- first_name: Josephine
full_name: Wesely, Josephine
last_name: Wesely
- first_name: Inka
full_name: Zörnig, Inka
last_name: Zörnig
- first_name: Matthias
full_name: Hammerschmidt, Matthias
last_name: Hammerschmidt
- first_name: Matthias
full_name: Nowak, Matthias
id: 30845DAA-F248-11E8-B48F-1D18A9856A87
last_name: Nowak
- first_name: Roland
full_name: Penzel, Roland
last_name: Penzel
- first_name: Kurt
full_name: Zatloukal, Kurt
last_name: Zatloukal
- first_name: Stefan
full_name: Joos, Stefan
last_name: Joos
- first_name: Ralf
full_name: Rieker, Ralf
last_name: Rieker
- first_name: Abbas
full_name: Agaimy, Abbas
last_name: Agaimy
- first_name: Stephan
full_name: Söder, Stephan
last_name: Söder
- first_name: Kmarie
full_name: Reid Lombardo, Kmarie
last_name: Reid Lombardo
- first_name: Michael
full_name: Kendrick, Michael
last_name: Kendrick
- first_name: Michael
full_name: Bardsley, Michael
last_name: Bardsley
- first_name: Yujiro
full_name: Hayashi, Yujiro
last_name: Hayashi
- first_name: David
full_name: Asuzu, David
last_name: Asuzu
- first_name: Sabriya
full_name: Syed, Sabriya
last_name: Syed
- first_name: Tamás
full_name: Ördög, Tamás
last_name: Ördög
- first_name: Martin
full_name: Zörnig, Martin
last_name: Zörnig
citation:
ama: Schwamb B, Pick R, Fernández S, et al. FAM96A is a novel pro-apoptotic tumor
suppressor in gastrointestinal stromal tumors. International Journal of Cancer.
2015;137(6):1318-1329. doi:10.1002/ijc.29498
apa: Schwamb, B., Pick, R., Fernández, S., Völp, K., Heering, J., Dötsch, V., …
Zörnig, M. (2015). FAM96A is a novel pro-apoptotic tumor suppressor in gastrointestinal
stromal tumors. International Journal of Cancer. Wiley. https://doi.org/10.1002/ijc.29498
chicago: Schwamb, Bettina, Robert Pick, Sara Fernández, Kirsten Völp, Jan Heering,
Volker Dötsch, Susanne Bösser, et al. “FAM96A Is a Novel Pro-Apoptotic Tumor Suppressor
in Gastrointestinal Stromal Tumors.” International Journal of Cancer. Wiley,
2015. https://doi.org/10.1002/ijc.29498.
ieee: B. Schwamb et al., “FAM96A is a novel pro-apoptotic tumor suppressor
in gastrointestinal stromal tumors,” International Journal of Cancer, vol.
137, no. 6. Wiley, pp. 1318–1329, 2015.
ista: Schwamb B, Pick R, Fernández S, Völp K, Heering J, Dötsch V, Bösser S, Jung
J, Beinoravičiute Kellner R, Wesely J, Zörnig I, Hammerschmidt M, Nowak M, Penzel
R, Zatloukal K, Joos S, Rieker R, Agaimy A, Söder S, Reid Lombardo K, Kendrick
M, Bardsley M, Hayashi Y, Asuzu D, Syed S, Ördög T, Zörnig M. 2015. FAM96A is
a novel pro-apoptotic tumor suppressor in gastrointestinal stromal tumors. International
Journal of Cancer. 137(6), 1318–1329.
mla: Schwamb, Bettina, et al. “FAM96A Is a Novel Pro-Apoptotic Tumor Suppressor
in Gastrointestinal Stromal Tumors.” International Journal of Cancer, vol.
137, no. 6, Wiley, 2015, pp. 1318–29, doi:10.1002/ijc.29498.
short: B. Schwamb, R. Pick, S. Fernández, K. Völp, J. Heering, V. Dötsch, S. Bösser,
J. Jung, R. Beinoravičiute Kellner, J. Wesely, I. Zörnig, M. Hammerschmidt, M.
Nowak, R. Penzel, K. Zatloukal, S. Joos, R. Rieker, A. Agaimy, S. Söder, K. Reid
Lombardo, M. Kendrick, M. Bardsley, Y. Hayashi, D. Asuzu, S. Syed, T. Ördög, M.
Zörnig, International Journal of Cancer 137 (2015) 1318–1329.
date_created: 2018-12-11T11:54:20Z
date_published: 2015-09-01T00:00:00Z
date_updated: 2021-01-12T06:53:36Z
day: '01'
department:
- _id: LifeSc
doi: 10.1002/ijc.29498
external_id:
pmid:
- '25716227'
intvolume: ' 137'
issue: '6'
language:
- iso: eng
main_file_link:
- open_access: '1'
url: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4497860/
month: '09'
oa: 1
oa_version: Submitted Version
page: 1318 - 1329
pmid: 1
publication: International Journal of Cancer
publication_status: published
publisher: Wiley
publist_id: '5253'
quality_controlled: '1'
scopus_import: 1
status: public
title: FAM96A is a novel pro-apoptotic tumor suppressor in gastrointestinal stromal
tumors
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 137
year: '2015'
...
---
_id: '1846'
abstract:
- lang: eng
text: Modal transition systems (MTS) is a well-studied specification formalism of
reactive systems supporting a step-wise refinement methodology. Despite its many
advantages, the formalism as well as its currently known extensions are incapable
of expressing some practically needed aspects in the refinement process like exclusive,
conditional and persistent choices. We introduce a new model called parametric
modal transition systems (PMTS) together with a general modal refinement notion
that overcomes many of the limitations. We investigate the computational complexity
of modal and thorough refinement checking on PMTS and its subclasses and provide
a direct encoding of the modal refinement problem into quantified Boolean formulae,
allowing us to employ state-of-the-art QBF solvers for modal refinement checking.
The experiments we report on show that the feasibility of refinement checking
is more influenced by the degree of nondeterminism rather than by the syntactic
restrictions on the types of formulae allowed in the description of the PMTS.
article_processing_charge: No
article_type: original
author:
- first_name: Nikola
full_name: Beneš, Nikola
last_name: Beneš
- first_name: Jan
full_name: Kretinsky, Jan
id: 44CEF464-F248-11E8-B48F-1D18A9856A87
last_name: Kretinsky
orcid: 0000-0002-8122-2881
- first_name: Kim
full_name: Larsen, Kim
last_name: Larsen
- first_name: Mikael
full_name: Möller, Mikael
last_name: Möller
- first_name: Salomon
full_name: Sickert, Salomon
last_name: Sickert
- first_name: Jiří
full_name: Srba, Jiří
last_name: Srba
citation:
ama: Beneš N, Kretinsky J, Larsen K, Möller M, Sickert S, Srba J. Refinement checking
on parametric modal transition systems. Acta Informatica. 2015;52(2-3):269-297.
doi:10.1007/s00236-015-0215-4
apa: Beneš, N., Kretinsky, J., Larsen, K., Möller, M., Sickert, S., & Srba,
J. (2015). Refinement checking on parametric modal transition systems. Acta
Informatica. Springer. https://doi.org/10.1007/s00236-015-0215-4
chicago: Beneš, Nikola, Jan Kretinsky, Kim Larsen, Mikael Möller, Salomon Sickert,
and Jiří Srba. “Refinement Checking on Parametric Modal Transition Systems.” Acta
Informatica. Springer, 2015. https://doi.org/10.1007/s00236-015-0215-4.
ieee: N. Beneš, J. Kretinsky, K. Larsen, M. Möller, S. Sickert, and J. Srba, “Refinement
checking on parametric modal transition systems,” Acta Informatica, vol.
52, no. 2–3. Springer, pp. 269–297, 2015.
ista: Beneš N, Kretinsky J, Larsen K, Möller M, Sickert S, Srba J. 2015. Refinement
checking on parametric modal transition systems. Acta Informatica. 52(2–3), 269–297.
mla: Beneš, Nikola, et al. “Refinement Checking on Parametric Modal Transition Systems.”
Acta Informatica, vol. 52, no. 2–3, Springer, 2015, pp. 269–97, doi:10.1007/s00236-015-0215-4.
short: N. Beneš, J. Kretinsky, K. Larsen, M. Möller, S. Sickert, J. Srba, Acta Informatica
52 (2015) 269–297.
date_created: 2018-12-11T11:54:20Z
date_published: 2015-04-01T00:00:00Z
date_updated: 2021-01-12T06:53:35Z
day: '01'
ddc:
- '000'
department:
- _id: ToHe
- _id: KrCh
doi: 10.1007/s00236-015-0215-4
ec_funded: 1
file:
- access_level: open_access
checksum: fb4037ddc4fc05f33080dd3547ede350
content_type: application/pdf
creator: dernst
date_created: 2020-05-15T08:57:44Z
date_updated: 2020-07-14T12:45:19Z
file_id: '7854'
file_name: 2015_ActaInfo_Benes.pdf
file_size: 488482
relation: main_file
file_date_updated: 2020-07-14T12:45:19Z
has_accepted_license: '1'
intvolume: ' 52'
issue: 2-3
language:
- iso: eng
month: '04'
oa: 1
oa_version: Submitted Version
page: 269 - 297
project:
- _id: 25EE3708-B435-11E9-9278-68D0E5697425
call_identifier: FP7
grant_number: '267989'
name: Quantitative Reactive Modeling
- _id: 25832EC2-B435-11E9-9278-68D0E5697425
call_identifier: FWF
grant_number: S 11407_N23
name: Rigorous Systems Engineering
publication: Acta Informatica
publication_status: published
publisher: Springer
publist_id: '5255'
quality_controlled: '1'
scopus_import: 1
status: public
title: Refinement checking on parametric modal transition systems
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 52
year: '2015'
...
---
_id: '1845'
abstract:
- lang: eng
text: Based on extrapolation from excitatory synapses, it is often assumed that
depletion of the releasable pool of synaptic vesicles is the main factor underlying
depression at inhibitory synapses. In this issue of Neuron, using subcellular
patch-clamp recording from inhibitory presynaptic terminals, Kawaguchi and Sakaba
(2015) show that at Purkinje cell-deep cerebellar nuclei neuron synapses, changes
in presynaptic action potential waveform substantially contribute to synaptic
depression. Based on extrapolation from excitatory synapses, it is often assumed
that depletion of the releasable pool of synaptic vesicles is the main factor
underlying depression at inhibitory synapses. In this issue of Neuron, using subcellular
patch-clamp recording from inhibitory presynaptic terminals, Kawaguchi and Sakaba
(2015) show that at Purkinje cell-deep cerebellar nuclei neuron synapses, changes
in presynaptic action potential waveform substantially contribute to synaptic
depression.
article_processing_charge: No
author:
- first_name: David H
full_name: Vandael, David H
id: 3AE48E0A-F248-11E8-B48F-1D18A9856A87
last_name: Vandael
orcid: 0000-0001-7577-1676
- first_name: 'Claudia '
full_name: 'Espinoza Martinez, Claudia '
id: 31FFEE2E-F248-11E8-B48F-1D18A9856A87
last_name: Espinoza Martinez
orcid: 0000-0003-4710-2082
- first_name: Peter M
full_name: Jonas, Peter M
id: 353C1B58-F248-11E8-B48F-1D18A9856A87
last_name: Jonas
orcid: 0000-0001-5001-4804
citation:
ama: Vandael DH, Espinoza Martinez C, Jonas PM. Excitement about inhibitory presynaptic
terminals. Neuron. 2015;85(6):1149-1151. doi:10.1016/j.neuron.2015.03.006
apa: Vandael, D. H., Espinoza Martinez, C., & Jonas, P. M. (2015). Excitement
about inhibitory presynaptic terminals. Neuron. Elsevier. https://doi.org/10.1016/j.neuron.2015.03.006
chicago: Vandael, David H, Claudia Espinoza Martinez, and Peter M Jonas. “Excitement
about Inhibitory Presynaptic Terminals.” Neuron. Elsevier, 2015. https://doi.org/10.1016/j.neuron.2015.03.006.
ieee: D. H. Vandael, C. Espinoza Martinez, and P. M. Jonas, “Excitement about inhibitory
presynaptic terminals,” Neuron, vol. 85, no. 6. Elsevier, pp. 1149–1151,
2015.
ista: Vandael DH, Espinoza Martinez C, Jonas PM. 2015. Excitement about inhibitory
presynaptic terminals. Neuron. 85(6), 1149–1151.
mla: Vandael, David H., et al. “Excitement about Inhibitory Presynaptic Terminals.”
Neuron, vol. 85, no. 6, Elsevier, 2015, pp. 1149–51, doi:10.1016/j.neuron.2015.03.006.
short: D.H. Vandael, C. Espinoza Martinez, P.M. Jonas, Neuron 85 (2015) 1149–1151.
date_created: 2018-12-11T11:54:19Z
date_published: 2015-03-18T00:00:00Z
date_updated: 2021-10-08T09:07:34Z
day: '18'
ddc:
- '570'
department:
- _id: PeJo
doi: 10.1016/j.neuron.2015.03.006
file:
- access_level: open_access
checksum: d1808550e376a0eca2a950fda017cfa6
content_type: application/pdf
creator: system
date_created: 2018-12-12T10:16:07Z
date_updated: 2020-07-14T12:45:19Z
file_id: '5192'
file_name: IST-2017-822-v1+1_Perspective_Fig__Final.pdf
file_size: 411832
relation: main_file
- access_level: open_access
checksum: a279f4ae61e6c8f33d68f69a0d02097d
content_type: application/pdf
creator: system
date_created: 2018-12-12T10:16:07Z
date_updated: 2020-07-14T12:45:19Z
file_id: '5193'
file_name: IST-2017-822-v1+2_Perspective_Final2.pdf
file_size: 100769
relation: main_file
file_date_updated: 2020-07-14T12:45:19Z
has_accepted_license: '1'
intvolume: ' 85'
issue: '6'
language:
- iso: eng
month: '03'
oa: 1
oa_version: Published Version
page: 1149 - 1151
publication: Neuron
publication_status: published
publisher: Elsevier
publist_id: '5256'
pubrep_id: '822'
quality_controlled: '1'
scopus_import: '1'
status: public
title: Excitement about inhibitory presynaptic terminals
tmp:
image: /images/cc_by_nc.png
legal_code_url: https://creativecommons.org/licenses/by-nc/4.0/legalcode
name: Creative Commons Attribution-NonCommercial 4.0 International (CC BY-NC 4.0)
short: CC BY-NC (4.0)
type: journal_article
user_id: 8b945eb4-e2f2-11eb-945a-df72226e66a9
volume: 85
year: '2015'
...
---
_id: '1840'
abstract:
- lang: eng
text: In this paper, we present a method for reducing a regular, discrete-time Markov
chain (DTMC) to another DTMC with a given, typically much smaller number of states.
The cost of reduction is defined as the Kullback-Leibler divergence rate between
a projection of the original process through a partition function and a DTMC on
the correspondingly partitioned state space. Finding the reduced model with minimal
cost is computationally expensive, as it requires an exhaustive search among all
state space partitions, and an exact evaluation of the reduction cost for each
candidate partition. Our approach deals with the latter problem by minimizing
an upper bound on the reduction cost instead of minimizing the exact cost. The
proposed upper bound is easy to compute and it is tight if the original chain
is lumpable with respect to the partition. Then, we express the problem in the
form of information bottleneck optimization, and propose using the agglomerative
information bottleneck algorithm for searching a suboptimal partition greedily,
rather than exhaustively. The theory is illustrated with examples and one application
scenario in the context of modeling bio-molecular interactions.
acknowledgement: "This work was supported by the Austrian Research Association under
Project 06/12684, by the Swiss National Science Foundation (SNSF) under Grant PP00P2
128503/1, by the SystemsX.ch (the Swiss Inititative for Systems Biology), and by
a SNSF Early Postdoc.Mobility Fellowship grant P2EZP2_148797.\r\n"
author:
- first_name: Bernhard
full_name: Geiger, Bernhard
last_name: Geiger
- first_name: Tatjana
full_name: Petrov, Tatjana
id: 3D5811FC-F248-11E8-B48F-1D18A9856A87
last_name: Petrov
orcid: 0000-0002-9041-0905
- first_name: Gernot
full_name: Kubin, Gernot
last_name: Kubin
- first_name: Heinz
full_name: Koeppl, Heinz
last_name: Koeppl
citation:
ama: Geiger B, Petrov T, Kubin G, Koeppl H. Optimal Kullback-Leibler aggregation
via information bottleneck. IEEE Transactions on Automatic Control. 2015;60(4):1010-1022.
doi:10.1109/TAC.2014.2364971
apa: Geiger, B., Petrov, T., Kubin, G., & Koeppl, H. (2015). Optimal Kullback-Leibler
aggregation via information bottleneck. IEEE Transactions on Automatic Control.
IEEE. https://doi.org/10.1109/TAC.2014.2364971
chicago: Geiger, Bernhard, Tatjana Petrov, Gernot Kubin, and Heinz Koeppl. “Optimal
Kullback-Leibler Aggregation via Information Bottleneck.” IEEE Transactions
on Automatic Control. IEEE, 2015. https://doi.org/10.1109/TAC.2014.2364971.
ieee: B. Geiger, T. Petrov, G. Kubin, and H. Koeppl, “Optimal Kullback-Leibler aggregation
via information bottleneck,” IEEE Transactions on Automatic Control, vol.
60, no. 4. IEEE, pp. 1010–1022, 2015.
ista: Geiger B, Petrov T, Kubin G, Koeppl H. 2015. Optimal Kullback-Leibler aggregation
via information bottleneck. IEEE Transactions on Automatic Control. 60(4), 1010–1022.
mla: Geiger, Bernhard, et al. “Optimal Kullback-Leibler Aggregation via Information
Bottleneck.” IEEE Transactions on Automatic Control, vol. 60, no. 4, IEEE,
2015, pp. 1010–22, doi:10.1109/TAC.2014.2364971.
short: B. Geiger, T. Petrov, G. Kubin, H. Koeppl, IEEE Transactions on Automatic
Control 60 (2015) 1010–1022.
date_created: 2018-12-11T11:54:18Z
date_published: 2015-04-01T00:00:00Z
date_updated: 2021-01-12T06:53:33Z
day: '01'
department:
- _id: CaGu
- _id: ToHe
doi: 10.1109/TAC.2014.2364971
intvolume: ' 60'
issue: '4'
language:
- iso: eng
main_file_link:
- open_access: '1'
url: http://arxiv.org/abs/1304.6603
month: '04'
oa: 1
oa_version: Preprint
page: 1010 - 1022
publication: IEEE Transactions on Automatic Control
publication_identifier:
issn:
- 0018-9286
publication_status: published
publisher: IEEE
publist_id: '5262'
quality_controlled: '1'
scopus_import: 1
status: public
title: Optimal Kullback-Leibler aggregation via information bottleneck
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 60
year: '2015'
...
---
_id: '1841'
abstract:
- lang: eng
text: We propose a new family of message passing techniques for MAP estimation in
graphical models which we call Sequential Reweighted Message Passing (SRMP). Special
cases include well-known techniques such as Min-Sum Diffusion (MSD) and a faster
Sequential Tree-Reweighted Message Passing (TRW-S). Importantly, our derivation
is simpler than the original derivation of TRW-S, and does not involve a decomposition
into trees. This allows easy generalizations. The new family of algorithms can
be viewed as a generalization of TRW-S from pairwise to higher-order graphical
models. We test SRMP on several real-world problems with promising results.
author:
- first_name: Vladimir
full_name: Kolmogorov, Vladimir
id: 3D50B0BA-F248-11E8-B48F-1D18A9856A87
last_name: Kolmogorov
citation:
ama: Kolmogorov V. A new look at reweighted message passing. IEEE Transactions
on Pattern Analysis and Machine Intelligence. 2015;37(5):919-930. doi:10.1109/TPAMI.2014.2363465
apa: Kolmogorov, V. (2015). A new look at reweighted message passing. IEEE Transactions
on Pattern Analysis and Machine Intelligence. IEEE. https://doi.org/10.1109/TPAMI.2014.2363465
chicago: Kolmogorov, Vladimir. “A New Look at Reweighted Message Passing.” IEEE
Transactions on Pattern Analysis and Machine Intelligence. IEEE, 2015. https://doi.org/10.1109/TPAMI.2014.2363465.
ieee: V. Kolmogorov, “A new look at reweighted message passing,” IEEE Transactions
on Pattern Analysis and Machine Intelligence, vol. 37, no. 5. IEEE, pp. 919–930,
2015.
ista: Kolmogorov V. 2015. A new look at reweighted message passing. IEEE Transactions
on Pattern Analysis and Machine Intelligence. 37(5), 919–930.
mla: Kolmogorov, Vladimir. “A New Look at Reweighted Message Passing.” IEEE Transactions
on Pattern Analysis and Machine Intelligence, vol. 37, no. 5, IEEE, 2015,
pp. 919–30, doi:10.1109/TPAMI.2014.2363465.
short: V. Kolmogorov, IEEE Transactions on Pattern Analysis and Machine Intelligence
37 (2015) 919–930.
date_created: 2018-12-11T11:54:18Z
date_published: 2015-05-01T00:00:00Z
date_updated: 2021-01-12T06:53:33Z
day: '01'
department:
- _id: VlKo
doi: 10.1109/TPAMI.2014.2363465
ec_funded: 1
intvolume: ' 37'
issue: '5'
language:
- iso: eng
main_file_link:
- open_access: '1'
url: http://arxiv.org/abs/1309.5655
month: '05'
oa: 1
oa_version: Preprint
page: 919 - 930
project:
- _id: 25FBA906-B435-11E9-9278-68D0E5697425
call_identifier: FP7
grant_number: '616160'
name: 'Discrete Optimization in Computer Vision: Theory and Practice'
publication: IEEE Transactions on Pattern Analysis and Machine Intelligence
publication_status: published
publisher: IEEE
publist_id: '5261'
quality_controlled: '1'
scopus_import: 1
status: public
title: A new look at reweighted message passing
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 37
year: '2015'
...
---
_id: '1849'
abstract:
- lang: eng
text: 'Cell polarity is a fundamental property of pro- and eukaryotic cells. It
is necessary for coordination of cell division, cell morphogenesis and signaling
processes. How polarity is generated and maintained is a complex issue governed
by interconnected feed-back regulations between small GTPase signaling and membrane
tension-based signaling that controls membrane trafficking, and cytoskeleton organization
and dynamics. Here, we will review the potential role for calcium as a crucial
signal that connects and coordinates the respective processes during polarization
processes in plants. This article is part of a Special Issue entitled: 13th European
Symposium on Calcium.'
acknowledgement: The contributing authors were supported by the Ghent University Special
Research Fund (to E.H.), the Interuniversity Attraction Poles Programme (IAP VI/33
and IUAP P7/29 ‘MARS’), the European Research Council (project ERC-2011-StG-20101109-PSDP,
to J.F.), and the Research Foundation Flanders (to S.V.).
author:
- first_name: Ellie
full_name: Himschoot, Ellie
last_name: Himschoot
- first_name: Tom
full_name: Beeckman, Tom
last_name: Beeckman
- first_name: Jiřĺ
full_name: Friml, Jiřĺ
id: 4159519E-F248-11E8-B48F-1D18A9856A87
last_name: Friml
orcid: 0000-0002-8302-7596
- first_name: Steffen
full_name: Vanneste, Steffen
last_name: Vanneste
citation:
ama: Himschoot E, Beeckman T, Friml J, Vanneste S. Calcium is an organizer of cell
polarity in plants. Biochimica et Biophysica Acta - Molecular Cell Research.
2015;1853(9):2168-2172. doi:10.1016/j.bbamcr.2015.02.017
apa: Himschoot, E., Beeckman, T., Friml, J., & Vanneste, S. (2015). Calcium
is an organizer of cell polarity in plants. Biochimica et Biophysica Acta -
Molecular Cell Research. Elsevier. https://doi.org/10.1016/j.bbamcr.2015.02.017
chicago: Himschoot, Ellie, Tom Beeckman, Jiří Friml, and Steffen Vanneste. “Calcium
Is an Organizer of Cell Polarity in Plants.” Biochimica et Biophysica Acta
- Molecular Cell Research. Elsevier, 2015. https://doi.org/10.1016/j.bbamcr.2015.02.017.
ieee: E. Himschoot, T. Beeckman, J. Friml, and S. Vanneste, “Calcium is an organizer
of cell polarity in plants,” Biochimica et Biophysica Acta - Molecular Cell
Research, vol. 1853, no. 9. Elsevier, pp. 2168–2172, 2015.
ista: Himschoot E, Beeckman T, Friml J, Vanneste S. 2015. Calcium is an organizer
of cell polarity in plants. Biochimica et Biophysica Acta - Molecular Cell Research.
1853(9), 2168–2172.
mla: Himschoot, Ellie, et al. “Calcium Is an Organizer of Cell Polarity in Plants.”
Biochimica et Biophysica Acta - Molecular Cell Research, vol. 1853, no.
9, Elsevier, 2015, pp. 2168–72, doi:10.1016/j.bbamcr.2015.02.017.
short: E. Himschoot, T. Beeckman, J. Friml, S. Vanneste, Biochimica et Biophysica
Acta - Molecular Cell Research 1853 (2015) 2168–2172.
date_created: 2018-12-11T11:54:21Z
date_published: 2015-09-01T00:00:00Z
date_updated: 2021-01-12T06:53:36Z
day: '01'
department:
- _id: JiFr
doi: 10.1016/j.bbamcr.2015.02.017
intvolume: ' 1853'
issue: '9'
language:
- iso: eng
month: '09'
oa_version: None
page: 2168 - 2172
publication: Biochimica et Biophysica Acta - Molecular Cell Research
publication_status: published
publisher: Elsevier
publist_id: '5252'
quality_controlled: '1'
scopus_import: 1
status: public
title: Calcium is an organizer of cell polarity in plants
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 1853
year: '2015'
...
---
_id: '1847'
acknowledgement: This work was supported by the European Research Council (project
ERC-2011-StG-20101109-PSDP), European Social Fund (CZ.1.07/2.3.00/20.0043), and
the Czech Science Foundation GAČR (GA13-40637S).
author:
- first_name: Peter
full_name: Grones, Peter
id: 399876EC-F248-11E8-B48F-1D18A9856A87
last_name: Grones
- first_name: Jiřĺ
full_name: Friml, Jiřĺ
id: 4159519E-F248-11E8-B48F-1D18A9856A87
last_name: Friml
orcid: 0000-0002-8302-7596
citation:
ama: 'Grones P, Friml J. ABP1: Finally docking. Molecular Plant. 2015;8(3):356-358.
doi:10.1016/j.molp.2014.12.013'
apa: 'Grones, P., & Friml, J. (2015). ABP1: Finally docking. Molecular Plant.
Elsevier. https://doi.org/10.1016/j.molp.2014.12.013'
chicago: 'Grones, Peter, and Jiří Friml. “ABP1: Finally Docking.” Molecular Plant.
Elsevier, 2015. https://doi.org/10.1016/j.molp.2014.12.013.'
ieee: 'P. Grones and J. Friml, “ABP1: Finally docking,” Molecular Plant,
vol. 8, no. 3. Elsevier, pp. 356–358, 2015.'
ista: 'Grones P, Friml J. 2015. ABP1: Finally docking. Molecular Plant. 8(3), 356–358.'
mla: 'Grones, Peter, and Jiří Friml. “ABP1: Finally Docking.” Molecular Plant,
vol. 8, no. 3, Elsevier, 2015, pp. 356–58, doi:10.1016/j.molp.2014.12.013.'
short: P. Grones, J. Friml, Molecular Plant 8 (2015) 356–358.
date_created: 2018-12-11T11:54:20Z
date_published: 2015-03-02T00:00:00Z
date_updated: 2021-01-12T06:53:35Z
day: '02'
department:
- _id: JiFr
doi: 10.1016/j.molp.2014.12.013
intvolume: ' 8'
issue: '3'
language:
- iso: eng
month: '03'
oa_version: None
page: 356 - 358
publication: Molecular Plant
publication_status: published
publisher: Elsevier
publist_id: '5254'
quality_controlled: '1'
scopus_import: 1
status: public
title: 'ABP1: Finally docking'
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 8
year: '2015'
...
---
_id: '1850'
abstract:
- lang: eng
text: 'Entomopathogenic fungi are potent biocontrol agents that are widely used
against insect pests, many of which are social insects. Nevertheless, theoretical
investigations of their particular life history are scarce. We develop a model
that takes into account the main distinguishing features between traditionally
studied diseases and obligate killing pathogens, like the (biocontrol-relevant)
insect-pathogenic fungi Metarhizium and Beauveria. First, obligate killing entomopathogenic
fungi produce new infectious particles (conidiospores) only after host death and
not yet on the living host. Second, the killing rates of entomopathogenic fungi
depend strongly on the initial exposure dosage, thus we explicitly consider the
pathogen load of individual hosts. Further, we make the model applicable not only
to solitary host species, but also to group living species by incorporating social
interactions between hosts, like the collective disease defences of insect societies.
Our results identify the optimal killing rate for the pathogen that minimises
its invasion threshold. Furthermore, we find that the rate of contact between
hosts has an ambivalent effect: dense interaction networks between individuals
are considered to facilitate disease outbreaks because of increased pathogen transmission.
In social insects, this is compensated by their collective disease defences, i.e.,
social immunity. For the type of pathogens considered here, we show that even
without social immunity, high contact rates between live individuals dilute the
pathogen in the host colony and hence can reduce individual pathogen loads below
disease-causing levels.'
author:
- first_name: Sebastian
full_name: Novak, Sebastian
id: 461468AE-F248-11E8-B48F-1D18A9856A87
last_name: Novak
- first_name: Sylvia
full_name: Cremer, Sylvia
id: 2F64EC8C-F248-11E8-B48F-1D18A9856A87
last_name: Cremer
orcid: 0000-0002-2193-3868
citation:
ama: 'Novak S, Cremer S. Fungal disease dynamics in insect societies: Optimal killing
rates and the ambivalent effect of high social interaction rates. Journal of
Theoretical Biology. 2015;372(5):54-64. doi:10.1016/j.jtbi.2015.02.018'
apa: 'Novak, S., & Cremer, S. (2015). Fungal disease dynamics in insect societies:
Optimal killing rates and the ambivalent effect of high social interaction rates.
Journal of Theoretical Biology. Elsevier. https://doi.org/10.1016/j.jtbi.2015.02.018'
chicago: 'Novak, Sebastian, and Sylvia Cremer. “Fungal Disease Dynamics in Insect
Societies: Optimal Killing Rates and the Ambivalent Effect of High Social Interaction
Rates.” Journal of Theoretical Biology. Elsevier, 2015. https://doi.org/10.1016/j.jtbi.2015.02.018.'
ieee: 'S. Novak and S. Cremer, “Fungal disease dynamics in insect societies: Optimal
killing rates and the ambivalent effect of high social interaction rates,” Journal
of Theoretical Biology, vol. 372, no. 5. Elsevier, pp. 54–64, 2015.'
ista: 'Novak S, Cremer S. 2015. Fungal disease dynamics in insect societies: Optimal
killing rates and the ambivalent effect of high social interaction rates. Journal
of Theoretical Biology. 372(5), 54–64.'
mla: 'Novak, Sebastian, and Sylvia Cremer. “Fungal Disease Dynamics in Insect Societies:
Optimal Killing Rates and the Ambivalent Effect of High Social Interaction Rates.”
Journal of Theoretical Biology, vol. 372, no. 5, Elsevier, 2015, pp. 54–64,
doi:10.1016/j.jtbi.2015.02.018.'
short: S. Novak, S. Cremer, Journal of Theoretical Biology 372 (2015) 54–64.
date_created: 2018-12-11T11:54:21Z
date_published: 2015-05-07T00:00:00Z
date_updated: 2021-01-12T06:53:37Z
day: '07'
ddc:
- '576'
department:
- _id: NiBa
- _id: SyCr
doi: 10.1016/j.jtbi.2015.02.018
ec_funded: 1
file:
- access_level: open_access
checksum: 3c0dcacc900bc45cc65a453dfda4ca43
content_type: application/pdf
creator: system
date_created: 2018-12-12T10:18:07Z
date_updated: 2020-07-14T12:45:19Z
file_id: '5326'
file_name: IST-2015-329-v1+1_manuscript.pdf
file_size: 1546914
relation: main_file
file_date_updated: 2020-07-14T12:45:19Z
has_accepted_license: '1'
intvolume: ' 372'
issue: '5'
language:
- iso: eng
month: '05'
oa: 1
oa_version: Submitted Version
page: 54 - 64
project:
- _id: 25B07788-B435-11E9-9278-68D0E5697425
call_identifier: FP7
grant_number: '250152'
name: Limits to selection in biology and in evolutionary computation
- _id: 25DC711C-B435-11E9-9278-68D0E5697425
call_identifier: FP7
grant_number: '243071'
name: 'Social Vaccination in Ant Colonies: from Individual Mechanisms to Society
Effects'
publication: Journal of Theoretical Biology
publication_status: published
publisher: Elsevier
publist_id: '5251'
pubrep_id: '329'
quality_controlled: '1'
scopus_import: 1
status: public
title: 'Fungal disease dynamics in insect societies: Optimal killing rates and the
ambivalent effect of high social interaction rates'
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 372
year: '2015'
...
---
_id: '1851'
abstract:
- lang: eng
text: We consider mating strategies for females who search for males sequentially
during a season of limited length. We show that the best strategy rejects a given
male type if encountered before a time-threshold but accepts him after. For frequency-independent
benefits, we obtain the optimal time-thresholds explicitly for both discrete and
continuous distributions of males, and allow for mistakes being made in assessing
the correct male type. When the benefits are indirect (genes for the offspring)
and the population is under frequency-dependent ecological selection, the benefits
depend on the mating strategy of other females as well. This case is particularly
relevant to speciation models that seek to explore the stability of reproductive
isolation by assortative mating under frequency-dependent ecological selection.
We show that the indirect benefits are to be quantified by the reproductive values
of couples, and describe how the evolutionarily stable time-thresholds can be
found. We conclude with an example based on the Levene model, in which we analyze
the evolutionarily stable assortative mating strategies and the strength of reproductive
isolation provided by them.
article_processing_charge: No
article_type: original
author:
- first_name: Tadeas
full_name: Priklopil, Tadeas
id: 3C869AA0-F248-11E8-B48F-1D18A9856A87
last_name: Priklopil
- first_name: Eva
full_name: Kisdi, Eva
last_name: Kisdi
- first_name: Mats
full_name: Gyllenberg, Mats
last_name: Gyllenberg
citation:
ama: Priklopil T, Kisdi E, Gyllenberg M. Evolutionarily stable mating decisions
for sequentially searching females and the stability of reproductive isolation
by assortative mating. Evolution. 2015;69(4):1015-1026. doi:10.1111/evo.12618
apa: Priklopil, T., Kisdi, E., & Gyllenberg, M. (2015). Evolutionarily stable
mating decisions for sequentially searching females and the stability of reproductive
isolation by assortative mating. Evolution. Wiley. https://doi.org/10.1111/evo.12618
chicago: Priklopil, Tadeas, Eva Kisdi, and Mats Gyllenberg. “Evolutionarily Stable
Mating Decisions for Sequentially Searching Females and the Stability of Reproductive
Isolation by Assortative Mating.” Evolution. Wiley, 2015. https://doi.org/10.1111/evo.12618.
ieee: T. Priklopil, E. Kisdi, and M. Gyllenberg, “Evolutionarily stable mating decisions
for sequentially searching females and the stability of reproductive isolation
by assortative mating,” Evolution, vol. 69, no. 4. Wiley, pp. 1015–1026,
2015.
ista: Priklopil T, Kisdi E, Gyllenberg M. 2015. Evolutionarily stable mating decisions
for sequentially searching females and the stability of reproductive isolation
by assortative mating. Evolution. 69(4), 1015–1026.
mla: Priklopil, Tadeas, et al. “Evolutionarily Stable Mating Decisions for Sequentially
Searching Females and the Stability of Reproductive Isolation by Assortative Mating.”
Evolution, vol. 69, no. 4, Wiley, 2015, pp. 1015–26, doi:10.1111/evo.12618.
short: T. Priklopil, E. Kisdi, M. Gyllenberg, Evolution 69 (2015) 1015–1026.
date_created: 2018-12-11T11:54:21Z
date_published: 2015-02-09T00:00:00Z
date_updated: 2022-06-07T10:52:37Z
day: '09'
ddc:
- '570'
department:
- _id: NiBa
- _id: KrCh
doi: 10.1111/evo.12618
ec_funded: 1
external_id:
pmid:
- '25662095'
file:
- access_level: open_access
checksum: 1e8be0b1d7598a78cd2623d8ee8e7798
content_type: application/pdf
creator: dernst
date_created: 2020-05-15T09:05:34Z
date_updated: 2020-07-14T12:45:19Z
file_id: '7855'
file_name: 2015_Evolution_Priklopil.pdf
file_size: 967214
relation: main_file
file_date_updated: 2020-07-14T12:45:19Z
has_accepted_license: '1'
intvolume: ' 69'
issue: '4'
language:
- iso: eng
month: '02'
oa: 1
oa_version: Submitted Version
page: 1015 - 1026
pmid: 1
project:
- _id: 25681D80-B435-11E9-9278-68D0E5697425
call_identifier: FP7
grant_number: '291734'
name: International IST Postdoc Fellowship Programme
publication: Evolution
publication_identifier:
eissn:
- 1558-5646
issn:
- 0014-3820
publication_status: published
publisher: Wiley
publist_id: '5249'
quality_controlled: '1'
scopus_import: '1'
status: public
title: Evolutionarily stable mating decisions for sequentially searching females and
the stability of reproductive isolation by assortative mating
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 69
year: '2015'
...
---
_id: '1859'
abstract:
- lang: eng
text: "Structural support vector machines (SSVMs) are amongst the best performing
models for structured computer vision tasks, such as semantic image segmentation
or human pose estimation. Training SSVMs, however, is computationally costly,
because it requires repeated calls to a structured prediction subroutine (called
\\emph{max-oracle}), which has to solve an optimization problem itself, e.g. a
graph cut.\r\nIn this work, we introduce a new algorithm for SSVM training that
is more efficient than earlier techniques when the max-oracle is computationally
expensive, as it is frequently the case in computer vision tasks. The main idea
is to (i) combine the recent stochastic Block-Coordinate Frank-Wolfe algorithm
with efficient hyperplane caching, and (ii) use an automatic selection rule for
deciding whether to call the exact max-oracle or to rely on an approximate one
based on the cached hyperplanes.\r\nWe show experimentally that this strategy
leads to faster convergence to the optimum with respect to the number of requires
oracle calls, and that this translates into faster convergence with respect to
the total runtime when the max-oracle is slow compared to the other steps of the
algorithm. "
author:
- first_name: Neel
full_name: Shah, Neel
id: 31ABAF80-F248-11E8-B48F-1D18A9856A87
last_name: Shah
- first_name: Vladimir
full_name: Kolmogorov, Vladimir
id: 3D50B0BA-F248-11E8-B48F-1D18A9856A87
last_name: Kolmogorov
- first_name: Christoph
full_name: Lampert, Christoph
id: 40C20FD2-F248-11E8-B48F-1D18A9856A87
last_name: Lampert
orcid: 0000-0001-8622-7887
citation:
ama: 'Shah N, Kolmogorov V, Lampert C. A multi-plane block-coordinate Frank-Wolfe
algorithm for training structural SVMs with a costly max-oracle. In: IEEE; 2015:2737-2745.
doi:10.1109/CVPR.2015.7298890'
apa: 'Shah, N., Kolmogorov, V., & Lampert, C. (2015). A multi-plane block-coordinate
Frank-Wolfe algorithm for training structural SVMs with a costly max-oracle (pp.
2737–2745). Presented at the CVPR: Computer Vision and Pattern Recognition, Boston,
MA, USA: IEEE. https://doi.org/10.1109/CVPR.2015.7298890'
chicago: Shah, Neel, Vladimir Kolmogorov, and Christoph Lampert. “A Multi-Plane
Block-Coordinate Frank-Wolfe Algorithm for Training Structural SVMs with a Costly
Max-Oracle,” 2737–45. IEEE, 2015. https://doi.org/10.1109/CVPR.2015.7298890.
ieee: 'N. Shah, V. Kolmogorov, and C. Lampert, “A multi-plane block-coordinate Frank-Wolfe
algorithm for training structural SVMs with a costly max-oracle,” presented at
the CVPR: Computer Vision and Pattern Recognition, Boston, MA, USA, 2015, pp.
2737–2745.'
ista: 'Shah N, Kolmogorov V, Lampert C. 2015. A multi-plane block-coordinate Frank-Wolfe
algorithm for training structural SVMs with a costly max-oracle. CVPR: Computer
Vision and Pattern Recognition, 2737–2745.'
mla: Shah, Neel, et al. A Multi-Plane Block-Coordinate Frank-Wolfe Algorithm
for Training Structural SVMs with a Costly Max-Oracle. IEEE, 2015, pp. 2737–45,
doi:10.1109/CVPR.2015.7298890.
short: N. Shah, V. Kolmogorov, C. Lampert, in:, IEEE, 2015, pp. 2737–2745.
conference:
end_date: 2015-06-12
location: Boston, MA, USA
name: 'CVPR: Computer Vision and Pattern Recognition'
start_date: 2015-06-07
date_created: 2018-12-11T11:54:24Z
date_published: 2015-06-01T00:00:00Z
date_updated: 2021-01-12T06:53:40Z
day: '01'
department:
- _id: VlKo
- _id: ChLa
doi: 10.1109/CVPR.2015.7298890
ec_funded: 1
language:
- iso: eng
main_file_link:
- open_access: '1'
url: http://arxiv.org/abs/1408.6804
month: '06'
oa: 1
oa_version: Preprint
page: 2737 - 2745
project:
- _id: 2532554C-B435-11E9-9278-68D0E5697425
call_identifier: FP7
grant_number: '308036'
name: Lifelong Learning of Visual Scene Understanding
- _id: 25FBA906-B435-11E9-9278-68D0E5697425
call_identifier: FP7
grant_number: '616160'
name: 'Discrete Optimization in Computer Vision: Theory and Practice'
publication_status: published
publisher: IEEE
publist_id: '5240'
quality_controlled: '1'
scopus_import: 1
status: public
title: A multi-plane block-coordinate Frank-Wolfe algorithm for training structural
SVMs with a costly max-oracle
type: conference
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
year: '2015'
...
---
_id: '1860'
abstract:
- lang: eng
text: Classifiers for object categorization are usually evaluated by their accuracy
on a set of i.i.d. test examples. This provides us with an estimate of the expected
error when applying the classifiers to a single new image. In real application,
however, classifiers are rarely only used for a single image and then discarded.
Instead, they are applied sequentially to many images, and these are typically
not i.i.d. samples from a fixed data distribution, but they carry dependencies
and their class distribution varies over time. In this work, we argue that the
phenomenon of correlated data at prediction time is not a nuisance, but a blessing
in disguise. We describe a probabilistic method for adapting classifiers at prediction
time without having to retrain them. We also introduce a framework for creating
realistically distributed image sequences, which offers a way to benchmark classifier
adaptation methods, such as the one we propose. Experiments on the ILSVRC2010
and ILSVRC2012 datasets show that adapting object classification systems at prediction
time can significantly reduce their error rate, even with no additional human
feedback.
author:
- first_name: Amélie
full_name: Royer, Amélie
last_name: Royer
- first_name: Christoph
full_name: Lampert, Christoph
id: 40C20FD2-F248-11E8-B48F-1D18A9856A87
last_name: Lampert
orcid: 0000-0001-8622-7887
citation:
ama: 'Royer A, Lampert C. Classifier adaptation at prediction time. In: IEEE; 2015:1401-1409.
doi:10.1109/CVPR.2015.7298746'
apa: 'Royer, A., & Lampert, C. (2015). Classifier adaptation at prediction time
(pp. 1401–1409). Presented at the CVPR: Computer Vision and Pattern Recognition,
Boston, MA, United States: IEEE. https://doi.org/10.1109/CVPR.2015.7298746'
chicago: Royer, Amélie, and Christoph Lampert. “Classifier Adaptation at Prediction
Time,” 1401–9. IEEE, 2015. https://doi.org/10.1109/CVPR.2015.7298746.
ieee: 'A. Royer and C. Lampert, “Classifier adaptation at prediction time,” presented
at the CVPR: Computer Vision and Pattern Recognition, Boston, MA, United States,
2015, pp. 1401–1409.'
ista: 'Royer A, Lampert C. 2015. Classifier adaptation at prediction time. CVPR:
Computer Vision and Pattern Recognition, 1401–1409.'
mla: Royer, Amélie, and Christoph Lampert. Classifier Adaptation at Prediction
Time. IEEE, 2015, pp. 1401–09, doi:10.1109/CVPR.2015.7298746.
short: A. Royer, C. Lampert, in:, IEEE, 2015, pp. 1401–1409.
conference:
end_date: 2015-06-12
location: Boston, MA, United States
name: 'CVPR: Computer Vision and Pattern Recognition'
start_date: 2015-06-07
date_created: 2018-12-11T11:54:24Z
date_published: 2015-06-01T00:00:00Z
date_updated: 2021-01-12T06:53:41Z
day: '01'
department:
- _id: ChLa
doi: 10.1109/CVPR.2015.7298746
ec_funded: 1
language:
- iso: eng
main_file_link:
- open_access: '1'
url: http://www.cv-foundation.org/openaccess/content_cvpr_2015/papers/Royer_Classifier_Adaptation_at_2015_CVPR_paper.pdf
month: '06'
oa: 1
oa_version: Submitted Version
page: 1401 - 1409
project:
- _id: 2532554C-B435-11E9-9278-68D0E5697425
call_identifier: FP7
grant_number: '308036'
name: Lifelong Learning of Visual Scene Understanding
publication_status: published
publisher: IEEE
publist_id: '5239'
quality_controlled: '1'
scopus_import: 1
status: public
title: Classifier adaptation at prediction time
type: conference
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
year: '2015'
...
---
_id: '1858'
abstract:
- lang: eng
text: 'We study the problem of predicting the future, though only in the probabilistic
sense of estimating a future state of a time-varying probability distribution.
This is not only an interesting academic problem, but solving this extrapolation
problem also has many practical application, e.g. for training classifiers that
have to operate under time-varying conditions. Our main contribution is a method
for predicting the next step of the time-varying distribution from a given sequence
of sample sets from earlier time steps. For this we rely on two recent machine
learning techniques: embedding probability distributions into a reproducing kernel
Hilbert space, and learning operators by vector-valued regression. We illustrate
the working principles and the practical usefulness of our method by experiments
on synthetic and real data. We also highlight an exemplary application: training
a classifier in a domain adaptation setting without having access to examples
from the test time distribution at training time.'
author:
- first_name: Christoph
full_name: Lampert, Christoph
id: 40C20FD2-F248-11E8-B48F-1D18A9856A87
last_name: Lampert
orcid: 0000-0001-8622-7887
citation:
ama: 'Lampert C. Predicting the future behavior of a time-varying probability distribution.
In: IEEE; 2015:942-950. doi:10.1109/CVPR.2015.7298696'
apa: 'Lampert, C. (2015). Predicting the future behavior of a time-varying probability
distribution (pp. 942–950). Presented at the CVPR: Computer Vision and Pattern
Recognition, Boston, MA, United States: IEEE. https://doi.org/10.1109/CVPR.2015.7298696'
chicago: Lampert, Christoph. “Predicting the Future Behavior of a Time-Varying Probability
Distribution,” 942–50. IEEE, 2015. https://doi.org/10.1109/CVPR.2015.7298696.
ieee: 'C. Lampert, “Predicting the future behavior of a time-varying probability
distribution,” presented at the CVPR: Computer Vision and Pattern Recognition,
Boston, MA, United States, 2015, pp. 942–950.'
ista: 'Lampert C. 2015. Predicting the future behavior of a time-varying probability
distribution. CVPR: Computer Vision and Pattern Recognition, 942–950.'
mla: Lampert, Christoph. Predicting the Future Behavior of a Time-Varying Probability
Distribution. IEEE, 2015, pp. 942–50, doi:10.1109/CVPR.2015.7298696.
short: C. Lampert, in:, IEEE, 2015, pp. 942–950.
conference:
end_date: 2015-06-12
location: Boston, MA, United States
name: 'CVPR: Computer Vision and Pattern Recognition'
start_date: 2015-06-07
date_created: 2018-12-11T11:54:24Z
date_published: 2015-10-15T00:00:00Z
date_updated: 2021-01-12T06:53:40Z
day: '15'
department:
- _id: ChLa
doi: 10.1109/CVPR.2015.7298696
external_id:
arxiv:
- '1406.5362'
language:
- iso: eng
main_file_link:
- open_access: '1'
url: https://arxiv.org/abs/1406.5362
month: '10'
oa: 1
oa_version: Preprint
page: 942 - 950
publication_status: published
publisher: IEEE
publist_id: '5241'
quality_controlled: '1'
scopus_import: 1
status: public
title: Predicting the future behavior of a time-varying probability distribution
type: conference
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
year: '2015'
...
---
_id: '1857'
abstract:
- lang: eng
text: 'Sharing information between multiple tasks enables algorithms to achieve
good generalization performance even from small amounts of training data. However,
in a realistic scenario of multi-task learning not all tasks are equally related
to each other, hence it could be advantageous to transfer information only between
the most related tasks. In this work we propose an approach that processes multiple
tasks in a sequence with sharing between subsequent tasks instead of solving all
tasks jointly. Subsequently, we address the question of curriculum learning of
tasks, i.e. finding the best order of tasks to be learned. Our approach is based
on a generalization bound criterion for choosing the task order that optimizes
the average expected classification performance over all tasks. Our experimental
results show that learning multiple related tasks sequentially can be more effective
than learning them jointly, the order in which tasks are being solved affects
the overall performance, and that our model is able to automatically discover
the favourable order of tasks. '
author:
- first_name: Anastasia
full_name: Pentina, Anastasia
id: 42E87FC6-F248-11E8-B48F-1D18A9856A87
last_name: Pentina
- first_name: Viktoriia
full_name: Sharmanska, Viktoriia
id: 2EA6D09E-F248-11E8-B48F-1D18A9856A87
last_name: Sharmanska
orcid: 0000-0003-0192-9308
- first_name: Christoph
full_name: Lampert, Christoph
id: 40C20FD2-F248-11E8-B48F-1D18A9856A87
last_name: Lampert
orcid: 0000-0001-8622-7887
citation:
ama: 'Pentina A, Sharmanska V, Lampert C. Curriculum learning of multiple tasks.
In: IEEE; 2015:5492-5500. doi:10.1109/CVPR.2015.7299188'
apa: 'Pentina, A., Sharmanska, V., & Lampert, C. (2015). Curriculum learning
of multiple tasks (pp. 5492–5500). Presented at the CVPR: Computer Vision and
Pattern Recognition, Boston, MA, United States: IEEE. https://doi.org/10.1109/CVPR.2015.7299188'
chicago: Pentina, Anastasia, Viktoriia Sharmanska, and Christoph Lampert. “Curriculum
Learning of Multiple Tasks,” 5492–5500. IEEE, 2015. https://doi.org/10.1109/CVPR.2015.7299188.
ieee: 'A. Pentina, V. Sharmanska, and C. Lampert, “Curriculum learning of multiple
tasks,” presented at the CVPR: Computer Vision and Pattern Recognition, Boston,
MA, United States, 2015, pp. 5492–5500.'
ista: 'Pentina A, Sharmanska V, Lampert C. 2015. Curriculum learning of multiple
tasks. CVPR: Computer Vision and Pattern Recognition, 5492–5500.'
mla: Pentina, Anastasia, et al. Curriculum Learning of Multiple Tasks. IEEE,
2015, pp. 5492–500, doi:10.1109/CVPR.2015.7299188.
short: A. Pentina, V. Sharmanska, C. Lampert, in:, IEEE, 2015, pp. 5492–5500.
conference:
end_date: 2015-06-12
location: Boston, MA, United States
name: 'CVPR: Computer Vision and Pattern Recognition'
start_date: 2015-06-07
date_created: 2018-12-11T11:54:23Z
date_published: 2015-06-01T00:00:00Z
date_updated: 2023-02-23T10:17:31Z
day: '01'
department:
- _id: ChLa
doi: 10.1109/CVPR.2015.7299188
language:
- iso: eng
main_file_link:
- open_access: '1'
url: http://arxiv.org/abs/1412.1353
month: '06'
oa: 1
oa_version: Preprint
page: 5492 - 5500
publication_status: published
publisher: IEEE
publist_id: '5243'
quality_controlled: '1'
scopus_import: 1
status: public
title: Curriculum learning of multiple tasks
type: conference
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
year: '2015'
...
---
_id: '1867'
abstract:
- lang: eng
text: Cultured mammalian cells essential are model systems in basic biology research,
production platforms of proteins for medical use, and testbeds in synthetic biology.
Flavin cofactors, in particular flavin mononucleotide (FMN) and flavin adenine
dinucleotide (FAD), are critical for cellular redox reactions and sense light
in naturally occurring photoreceptors and optogenetic tools. Here, we quantified
flavin contents of commonly used mammalian cell lines. We first compared three
procedures for extraction of free and noncovalently protein-bound flavins and
verified extraction using fluorescence spectroscopy. For separation, two CE methods
with different BGEs were established, and detection was performed by LED-induced
fluorescence with limit of detections (LODs 0.5-3.8 nM). We found that riboflavin
(RF), FMN, and FAD contents varied significantly between cell lines. RF (3.1-14
amol/cell) and FAD (2.2-17.0 amol/cell) were the predominant flavins, while FMN
(0.46-3.4 amol/cell) was found at markedly lower levels. Observed flavin contents
agree with those previously extracted from mammalian tissues, yet reduced forms
of RF were detected that were not described previously. Quantification of flavins
in mammalian cell lines will allow a better understanding of cellular redox reactions
and optogenetic tools.
author:
- first_name: Jens
full_name: Hühner, Jens
last_name: Hühner
- first_name: Álvaro
full_name: Inglés Prieto, Álvaro
id: 2A9DB292-F248-11E8-B48F-1D18A9856A87
last_name: Inglés Prieto
orcid: 0000-0002-5409-8571
- first_name: Christian
full_name: Neusüß, Christian
last_name: Neusüß
- first_name: Michael
full_name: Lämmerhofer, Michael
last_name: Lämmerhofer
- first_name: Harald L
full_name: Janovjak, Harald L
id: 33BA6C30-F248-11E8-B48F-1D18A9856A87
last_name: Janovjak
orcid: 0000-0002-8023-9315
citation:
ama: Hühner J, Inglés Prieto Á, Neusüß C, Lämmerhofer M, Janovjak HL. Quantification
of riboflavin, flavin mononucleotide, and flavin adenine dinucleotide in mammalian
model cells by CE with LED-induced fluorescence detection. Electrophoresis.
2015;36(4):518-525. doi:10.1002/elps.201400451
apa: Hühner, J., Inglés Prieto, Á., Neusüß, C., Lämmerhofer, M., & Janovjak,
H. L. (2015). Quantification of riboflavin, flavin mononucleotide, and flavin
adenine dinucleotide in mammalian model cells by CE with LED-induced fluorescence
detection. Electrophoresis. Wiley. https://doi.org/10.1002/elps.201400451
chicago: Hühner, Jens, Álvaro Inglés Prieto, Christian Neusüß, Michael Lämmerhofer,
and Harald L Janovjak. “Quantification of Riboflavin, Flavin Mononucleotide, and
Flavin Adenine Dinucleotide in Mammalian Model Cells by CE with LED-Induced Fluorescence
Detection.” Electrophoresis. Wiley, 2015. https://doi.org/10.1002/elps.201400451.
ieee: J. Hühner, Á. Inglés Prieto, C. Neusüß, M. Lämmerhofer, and H. L. Janovjak,
“Quantification of riboflavin, flavin mononucleotide, and flavin adenine dinucleotide
in mammalian model cells by CE with LED-induced fluorescence detection,” Electrophoresis,
vol. 36, no. 4. Wiley, pp. 518–525, 2015.
ista: Hühner J, Inglés Prieto Á, Neusüß C, Lämmerhofer M, Janovjak HL. 2015. Quantification
of riboflavin, flavin mononucleotide, and flavin adenine dinucleotide in mammalian
model cells by CE with LED-induced fluorescence detection. Electrophoresis. 36(4),
518–525.
mla: Hühner, Jens, et al. “Quantification of Riboflavin, Flavin Mononucleotide,
and Flavin Adenine Dinucleotide in Mammalian Model Cells by CE with LED-Induced
Fluorescence Detection.” Electrophoresis, vol. 36, no. 4, Wiley, 2015,
pp. 518–25, doi:10.1002/elps.201400451.
short: J. Hühner, Á. Inglés Prieto, C. Neusüß, M. Lämmerhofer, H.L. Janovjak, Electrophoresis
36 (2015) 518–525.
date_created: 2018-12-11T11:54:26Z
date_published: 2015-02-01T00:00:00Z
date_updated: 2021-01-12T06:53:43Z
day: '01'
department:
- _id: HaJa
doi: 10.1002/elps.201400451
ec_funded: 1
intvolume: ' 36'
issue: '4'
language:
- iso: eng
month: '02'
oa_version: None
page: 518 - 525
project:
- _id: 25548C20-B435-11E9-9278-68D0E5697425
call_identifier: FP7
grant_number: '303564'
name: Microbial Ion Channels for Synthetic Neurobiology
- _id: 255BFFFA-B435-11E9-9278-68D0E5697425
grant_number: RGY0084/2012
name: In situ real-time imaging of neurotransmitter signaling using designer optical
sensors (HFSP Young Investigator)
publication: Electrophoresis
publication_status: published
publisher: Wiley
publist_id: '5230'
pubrep_id: '836'
quality_controlled: '1'
scopus_import: 1
status: public
title: Quantification of riboflavin, flavin mononucleotide, and flavin adenine dinucleotide
in mammalian model cells by CE with LED-induced fluorescence detection
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 36
year: '2015'
...
---
_id: '1865'
abstract:
- lang: eng
text: The plant hormone auxin and its directional transport are known to play a
crucial role in defining the embryonic axis and subsequent development of the
body plan. Although the role of PIN auxin efflux transporters has been clearly
assigned during embryonic shoot and root specification, the role of the auxin
influx carriers AUX1 and LIKE-AUX1 (LAX) proteins is not well established. Here,
we used chemical and genetic tools on Brassica napus microspore-derived embryos
and Arabidopsis thaliana zygotic embryos, and demonstrate that AUX1, LAX1 and
LAX2 are required for both shoot and root pole formation, in concert with PIN
efflux carriers. Furthermore, we uncovered a positive-feedback loop betweenMONOPTEROS(ARF5)-dependent
auxin signalling and auxin transport. ThisMONOPTEROSdependent transcriptional
regulation of auxin influx (AUX1, LAX1 and LAX2) and auxin efflux (PIN1 and PIN4)
carriers by MONOPTEROS helps to maintain proper auxin transport to the root tip.
These results indicate that auxin-dependent cell specification during embryo development
requires balanced auxin transport involving both influx and efflux mechanisms,
and that this transport is maintained by a positive transcriptional feedback on
auxin signalling.
acknowledgement: W.G. is a post-doctoral fellow of the Research Foundation Flanders.
H.S.R. is supported by Employment of Best Young Scientists for International Cooperation
Empowerment [CZ.1.07/2.3.00/30.0037], co-financed by the European Social Fund and
the state budget of the Czech Republic. Mi.S. was funded by the Ramón y Cajal program.
This work was supported by the European Research Council [project ERC-2011-StG-20101109-PSDP],
project ‘CEITEC – Central European Institute of Technology’ [CZ.1.05/1.1.00/02.0068],
the European Social Fund [CZ.1.07/2.3.00/20.0043] and the Czech Science Foundation
GACR [GA13-40637S] to J.F. We acknowledge funding from the Biological and Biotechnological
Science Research Council (BBSRC) and Engineering Physics Science Research Council
(EPSRC) to R.S. and M.B
author:
- first_name: Hélène
full_name: Robert, Hélène
last_name: Robert
- first_name: Wim
full_name: Grunewald, Wim
last_name: Grunewald
- first_name: Michael
full_name: Sauer, Michael
last_name: Sauer
- first_name: Bernard
full_name: Cannoot, Bernard
last_name: Cannoot
- first_name: Mercedes
full_name: Soriano, Mercedes
last_name: Soriano
- first_name: Ranjan
full_name: Swarup, Ranjan
last_name: Swarup
- first_name: Dolf
full_name: Weijers, Dolf
last_name: Weijers
- first_name: Malcolm
full_name: Bennett, Malcolm
last_name: Bennett
- first_name: Kim
full_name: Boutilier, Kim
last_name: Boutilier
- first_name: Jirí
full_name: Friml, Jirí
id: 4159519E-F248-11E8-B48F-1D18A9856A87
last_name: Friml
orcid: 0000-0002-8302-7596
citation:
ama: Robert H, Grunewald W, Sauer M, et al. Plant embryogenesis requires AUX/LAX-mediated
auxin influx. Development. 2015;142(4):702-711. doi:10.1242/dev.115832
apa: Robert, H., Grunewald, W., Sauer, M., Cannoot, B., Soriano, M., Swarup, R.,
… Friml, J. (2015). Plant embryogenesis requires AUX/LAX-mediated auxin influx.
Development. Company of Biologists. https://doi.org/10.1242/dev.115832
chicago: Robert, Hélène, Wim Grunewald, Michael Sauer, Bernard Cannoot, Mercedes
Soriano, Ranjan Swarup, Dolf Weijers, Malcolm Bennett, Kim Boutilier, and Jiří
Friml. “Plant Embryogenesis Requires AUX/LAX-Mediated Auxin Influx.” Development.
Company of Biologists, 2015. https://doi.org/10.1242/dev.115832.
ieee: H. Robert et al., “Plant embryogenesis requires AUX/LAX-mediated auxin
influx,” Development, vol. 142, no. 4. Company of Biologists, pp. 702–711,
2015.
ista: Robert H, Grunewald W, Sauer M, Cannoot B, Soriano M, Swarup R, Weijers D,
Bennett M, Boutilier K, Friml J. 2015. Plant embryogenesis requires AUX/LAX-mediated
auxin influx. Development. 142(4), 702–711.
mla: Robert, Hélène, et al. “Plant Embryogenesis Requires AUX/LAX-Mediated Auxin
Influx.” Development, vol. 142, no. 4, Company of Biologists, 2015, pp.
702–11, doi:10.1242/dev.115832.
short: H. Robert, W. Grunewald, M. Sauer, B. Cannoot, M. Soriano, R. Swarup, D.
Weijers, M. Bennett, K. Boutilier, J. Friml, Development 142 (2015) 702–711.
date_created: 2018-12-11T11:54:26Z
date_published: 2015-02-15T00:00:00Z
date_updated: 2021-01-12T06:53:43Z
day: '15'
department:
- _id: JiFr
doi: 10.1242/dev.115832
ec_funded: 1
intvolume: ' 142'
issue: '4'
language:
- iso: eng
month: '02'
oa_version: None
page: 702 - 711
project:
- _id: 25716A02-B435-11E9-9278-68D0E5697425
call_identifier: FP7
grant_number: '282300'
name: Polarity and subcellular dynamics in plants
publication: Development
publication_status: published
publisher: Company of Biologists
publist_id: '5231'
quality_controlled: '1'
scopus_import: 1
status: public
title: Plant embryogenesis requires AUX/LAX-mediated auxin influx
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 142
year: '2015'
...
---
_id: '1868'
abstract:
- lang: eng
text: We investigate high-dimensional nonlinear dynamical systems exhibiting multiple
resonances under adiabatic parameter variations. Our motivations come from experimental
considerations where time-dependent sweeping of parameters is a practical approach
to probing and characterizing the bifurcations of the system. The question is
whether bifurcations so detected are faithful representations of the bifurcations
intrinsic to the original stationary system. Utilizing a harmonically forced,
closed fluid flow system that possesses multiple resonances and solving the Navier-Stokes
equation under proper boundary conditions, we uncover the phenomenon of the early
effect. Specifically, as a control parameter, e.g., the driving frequency, is
adiabatically increased from an initial value, resonances emerge at frequency
values that are lower than those in the corresponding stationary system. The phenomenon
is established by numerical characterization of physical quantities through the
resonances, which include the kinetic energy and the vorticity field, and a heuristic
analysis based on the concept of instantaneous frequency. A simple formula is
obtained which relates the resonance points in the time-dependent and time-independent
systems. Our findings suggest that, in general, any true bifurcation of a nonlinear
dynamical system can be unequivocally uncovered through adiabatic parameter sweeping,
in spite of a shift in the bifurcation point, which is of value to experimental
studies of nonlinear dynamical systems.
article_number: '022906'
author:
- first_name: Youngyong
full_name: Park, Youngyong
last_name: Park
- first_name: Younghae
full_name: Do, Younghae
last_name: Do
- first_name: Sebastian
full_name: Altmeyer, Sebastian
id: 2EE67FDC-F248-11E8-B48F-1D18A9856A87
last_name: Altmeyer
orcid: 0000-0001-5964-0203
- first_name: Yingcheng
full_name: Lai, Yingcheng
last_name: Lai
- first_name: Gyuwon
full_name: Lee, Gyuwon
last_name: Lee
citation:
ama: Park Y, Do Y, Altmeyer S, Lai Y, Lee G. Early effect in time-dependent, high-dimensional
nonlinear dynamical systems with multiple resonances. Physical Review E.
2015;91(2). doi:10.1103/PhysRevE.91.022906
apa: Park, Y., Do, Y., Altmeyer, S., Lai, Y., & Lee, G. (2015). Early effect
in time-dependent, high-dimensional nonlinear dynamical systems with multiple
resonances. Physical Review E. American Physical Society. https://doi.org/10.1103/PhysRevE.91.022906
chicago: Park, Youngyong, Younghae Do, Sebastian Altmeyer, Yingcheng Lai, and Gyuwon
Lee. “Early Effect in Time-Dependent, High-Dimensional Nonlinear Dynamical Systems
with Multiple Resonances.” Physical Review E. American Physical Society,
2015. https://doi.org/10.1103/PhysRevE.91.022906.
ieee: Y. Park, Y. Do, S. Altmeyer, Y. Lai, and G. Lee, “Early effect in time-dependent,
high-dimensional nonlinear dynamical systems with multiple resonances,” Physical
Review E, vol. 91, no. 2. American Physical Society, 2015.
ista: Park Y, Do Y, Altmeyer S, Lai Y, Lee G. 2015. Early effect in time-dependent,
high-dimensional nonlinear dynamical systems with multiple resonances. Physical
Review E. 91(2), 022906.
mla: Park, Youngyong, et al. “Early Effect in Time-Dependent, High-Dimensional Nonlinear
Dynamical Systems with Multiple Resonances.” Physical Review E, vol. 91,
no. 2, 022906, American Physical Society, 2015, doi:10.1103/PhysRevE.91.022906.
short: Y. Park, Y. Do, S. Altmeyer, Y. Lai, G. Lee, Physical Review E 91 (2015).
date_created: 2018-12-11T11:54:27Z
date_published: 2015-02-09T00:00:00Z
date_updated: 2021-01-12T06:53:44Z
day: '09'
department:
- _id: BjHo
doi: 10.1103/PhysRevE.91.022906
intvolume: ' 91'
issue: '2'
language:
- iso: eng
month: '02'
oa_version: None
publication: Physical Review E
publication_identifier:
issn:
- 1539-3755
publication_status: published
publisher: American Physical Society
publist_id: '5229'
quality_controlled: '1'
scopus_import: 1
status: public
title: Early effect in time-dependent, high-dimensional nonlinear dynamical systems
with multiple resonances
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 91
year: '2015'
...
---
_id: '1864'
abstract:
- lang: eng
text: "The Altshuler–Shklovskii formulas (Altshuler and Shklovskii, BZh Eksp Teor
Fiz 91:200, 1986) predict, for any disordered quantum system in the diffusive
regime, a universal power law behaviour for the correlation functions of the mesoscopic
eigenvalue density. In this paper and its companion (Erdős and Knowles, The Altshuler–Shklovskii
formulas for random band matrices I: the unimodular case, 2013), we prove these
formulas for random band matrices. In (Erdős and Knowles, The Altshuler–Shklovskii
formulas for random band matrices I: the unimodular case, 2013) we introduced
a diagrammatic approach and presented robust estimates on general diagrams under
certain simplifying assumptions. In this paper, we remove these assumptions by
giving a general estimate of the subleading diagrams. We also give a precise analysis
of the leading diagrams which give rise to the Altschuler–Shklovskii power laws.
Moreover, we introduce a family of general random band matrices which interpolates
between real symmetric (β = 1) and complex Hermitian (β = 2) models, and track
the transition for the mesoscopic density–density correlation. Finally, we address
the higher-order correlation functions by proving that they behave asymptotically
according to a Gaussian process whose covariance is given by the Altshuler–Shklovskii
formulas.\r\n"
author:
- first_name: László
full_name: Erdös, László
id: 4DBD5372-F248-11E8-B48F-1D18A9856A87
last_name: Erdös
orcid: 0000-0001-5366-9603
- first_name: Antti
full_name: Knowles, Antti
last_name: Knowles
citation:
ama: 'Erdös L, Knowles A. The Altshuler–Shklovskii formulas for random band matrices
II: The general case. Annales Henri Poincare. 2015;16(3):709-799. doi:10.1007/s00023-014-0333-5'
apa: 'Erdös, L., & Knowles, A. (2015). The Altshuler–Shklovskii formulas for
random band matrices II: The general case. Annales Henri Poincare. Springer.
https://doi.org/10.1007/s00023-014-0333-5'
chicago: 'Erdös, László, and Antti Knowles. “The Altshuler–Shklovskii Formulas for
Random Band Matrices II: The General Case.” Annales Henri Poincare. Springer,
2015. https://doi.org/10.1007/s00023-014-0333-5.'
ieee: 'L. Erdös and A. Knowles, “The Altshuler–Shklovskii formulas for random band
matrices II: The general case,” Annales Henri Poincare, vol. 16, no. 3.
Springer, pp. 709–799, 2015.'
ista: 'Erdös L, Knowles A. 2015. The Altshuler–Shklovskii formulas for random band
matrices II: The general case. Annales Henri Poincare. 16(3), 709–799.'
mla: 'Erdös, László, and Antti Knowles. “The Altshuler–Shklovskii Formulas for Random
Band Matrices II: The General Case.” Annales Henri Poincare, vol. 16, no.
3, Springer, 2015, pp. 709–99, doi:10.1007/s00023-014-0333-5.'
short: L. Erdös, A. Knowles, Annales Henri Poincare 16 (2015) 709–799.
date_created: 2018-12-11T11:54:26Z
date_published: 2015-03-01T00:00:00Z
date_updated: 2021-01-12T06:53:42Z
day: '01'
department:
- _id: LaEr
doi: 10.1007/s00023-014-0333-5
ec_funded: 1
intvolume: ' 16'
issue: '3'
language:
- iso: eng
main_file_link:
- open_access: '1'
url: http://arxiv.org/abs/1309.5107
month: '03'
oa: 1
oa_version: Preprint
page: 709 - 799
project:
- _id: 258DCDE6-B435-11E9-9278-68D0E5697425
call_identifier: FP7
grant_number: '338804'
name: Random matrices, universality and disordered quantum systems
publication: Annales Henri Poincare
publication_status: published
publisher: Springer
publist_id: '5233'
scopus_import: 1
status: public
title: 'The Altshuler–Shklovskii formulas for random band matrices II: The general
case'
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 16
year: '2015'
...
---
_id: '1861'
abstract:
- lang: eng
text: Continuous-time Markov chains are commonly used in practice for modeling biochemical
reaction networks in which the inherent randomness of themolecular interactions
cannot be ignored. This has motivated recent research effort into methods for
parameter inference and experiment design for such models. The major difficulty
is that such methods usually require one to iteratively solve the chemical master
equation that governs the time evolution of the probability distribution of the
system. This, however, is rarely possible, and even approximation techniques remain
limited to relatively small and simple systems. An alternative explored in this
article is to base methods on only some low-order moments of the entire probability
distribution. We summarize the theory behind such moment-based methods for parameter
inference and experiment design and provide new case studies where we investigate
their performance.
acknowledgement: "HYCON2; EC; European Commission\r\n"
article_number: '8'
author:
- first_name: Jakob
full_name: Ruess, Jakob
id: 4A245D00-F248-11E8-B48F-1D18A9856A87
last_name: Ruess
orcid: 0000-0003-1615-3282
- first_name: John
full_name: Lygeros, John
last_name: Lygeros
citation:
ama: Ruess J, Lygeros J. Moment-based methods for parameter inference and experiment
design for stochastic biochemical reaction networks. ACM Transactions on Modeling
and Computer Simulation. 2015;25(2). doi:10.1145/2688906
apa: Ruess, J., & Lygeros, J. (2015). Moment-based methods for parameter inference
and experiment design for stochastic biochemical reaction networks. ACM Transactions
on Modeling and Computer Simulation. ACM. https://doi.org/10.1145/2688906
chicago: Ruess, Jakob, and John Lygeros. “Moment-Based Methods for Parameter Inference
and Experiment Design for Stochastic Biochemical Reaction Networks.” ACM Transactions
on Modeling and Computer Simulation. ACM, 2015. https://doi.org/10.1145/2688906.
ieee: J. Ruess and J. Lygeros, “Moment-based methods for parameter inference and
experiment design for stochastic biochemical reaction networks,” ACM Transactions
on Modeling and Computer Simulation, vol. 25, no. 2. ACM, 2015.
ista: Ruess J, Lygeros J. 2015. Moment-based methods for parameter inference and
experiment design for stochastic biochemical reaction networks. ACM Transactions
on Modeling and Computer Simulation. 25(2), 8.
mla: Ruess, Jakob, and John Lygeros. “Moment-Based Methods for Parameter Inference
and Experiment Design for Stochastic Biochemical Reaction Networks.” ACM Transactions
on Modeling and Computer Simulation, vol. 25, no. 2, 8, ACM, 2015, doi:10.1145/2688906.
short: J. Ruess, J. Lygeros, ACM Transactions on Modeling and Computer Simulation
25 (2015).
date_created: 2018-12-11T11:54:25Z
date_published: 2015-02-01T00:00:00Z
date_updated: 2021-01-12T06:53:41Z
day: '01'
department:
- _id: ToHe
- _id: GaTk
doi: 10.1145/2688906
intvolume: ' 25'
issue: '2'
language:
- iso: eng
month: '02'
oa_version: None
publication: ACM Transactions on Modeling and Computer Simulation
publication_status: published
publisher: ACM
publist_id: '5238'
quality_controlled: '1'
scopus_import: 1
status: public
title: Moment-based methods for parameter inference and experiment design for stochastic
biochemical reaction networks
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 25
year: '2015'
...
---
_id: '1866'
author:
- first_name: Thomas A
full_name: Henzinger, Thomas A
id: 40876CD8-F248-11E8-B48F-1D18A9856A87
last_name: Henzinger
orcid: 0000−0002−2985−7724
- first_name: Jean
full_name: Raskin, Jean
last_name: Raskin
citation:
ama: 'Henzinger TA, Raskin J. The equivalence problem for finite automata: Technical
perspective. Communications of the ACM. 2015;58(2):86-86. doi:10.1145/2701001'
apa: 'Henzinger, T. A., & Raskin, J. (2015). The equivalence problem for finite
automata: Technical perspective. Communications of the ACM. ACM. https://doi.org/10.1145/2701001'
chicago: 'Henzinger, Thomas A, and Jean Raskin. “The Equivalence Problem for Finite
Automata: Technical Perspective.” Communications of the ACM. ACM, 2015.
https://doi.org/10.1145/2701001.'
ieee: 'T. A. Henzinger and J. Raskin, “The equivalence problem for finite automata:
Technical perspective,” Communications of the ACM, vol. 58, no. 2. ACM,
pp. 86–86, 2015.'
ista: 'Henzinger TA, Raskin J. 2015. The equivalence problem for finite automata:
Technical perspective. Communications of the ACM. 58(2), 86–86.'
mla: 'Henzinger, Thomas A., and Jean Raskin. “The Equivalence Problem for Finite
Automata: Technical Perspective.” Communications of the ACM, vol. 58, no.
2, ACM, 2015, pp. 86–86, doi:10.1145/2701001.'
short: T.A. Henzinger, J. Raskin, Communications of the ACM 58 (2015) 86–86.
date_created: 2018-12-11T11:54:26Z
date_published: 2015-01-28T00:00:00Z
date_updated: 2021-01-12T06:53:43Z
day: '28'
department:
- _id: ToHe
doi: 10.1145/2701001
intvolume: ' 58'
issue: '2'
language:
- iso: eng
month: '01'
oa_version: None
page: 86-86
publication: Communications of the ACM
publication_status: published
publisher: ACM
publist_id: '5232'
scopus_import: 1
status: public
title: 'The equivalence problem for finite automata: Technical perspective'
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 58
year: '2015'
...
---
_id: '1871'
abstract:
- lang: eng
text: The plant hormone auxin is a key regulator of plant growth and development.
Differences in auxin distribution within tissues are mediated by the polar auxin
transport machinery, and cellular auxin responses occur depending on changes in
cellular auxin levels. Multiple receptor systems at the cell surface and in the
interior operate to sense and interpret fluctuations in auxin distribution that
occur during plant development. Until now, three proteins or protein complexes
that can bind auxin have been identified. SCFTIR1 [a SKP1-cullin-1-F-box complex
that contains transport inhibitor response 1 (TIR1) as the F-box protein] and
S-phase-kinaseassociated protein 2 (SKP2) localize to the nucleus, whereas auxinbinding
protein 1 (ABP1), predominantly associates with the endoplasmic reticulum and
cell surface. In this Cell Science at a Glance article, we summarize recent discoveries
in the field of auxin transport and signaling that have led to the identification
of new components of these pathways, as well as their mutual interaction.
acknowledgement: This work was supported by the European Research Council [project
ERC-2011-StG-20101109-PSDP]; European Social Fund [grant number CZ.1.07/2.3.00/20.0043]
and the Czech Science Foundation GAČR [grant number GA13-40637S]
author:
- first_name: Peter
full_name: Grones, Peter
id: 399876EC-F248-11E8-B48F-1D18A9856A87
last_name: Grones
- first_name: Jirí
full_name: Friml, Jirí
id: 4159519E-F248-11E8-B48F-1D18A9856A87
last_name: Friml
orcid: 0000-0002-8302-7596
citation:
ama: Grones P, Friml J. Auxin transporters and binding proteins at a glance. Journal
of Cell Science. 2015;128(1):1-7. doi:10.1242/jcs.159418
apa: Grones, P., & Friml, J. (2015). Auxin transporters and binding proteins
at a glance. Journal of Cell Science. Company of Biologists. https://doi.org/10.1242/jcs.159418
chicago: Grones, Peter, and Jiří Friml. “Auxin Transporters and Binding Proteins
at a Glance.” Journal of Cell Science. Company of Biologists, 2015. https://doi.org/10.1242/jcs.159418.
ieee: P. Grones and J. Friml, “Auxin transporters and binding proteins at a glance,”
Journal of Cell Science, vol. 128, no. 1. Company of Biologists, pp. 1–7,
2015.
ista: Grones P, Friml J. 2015. Auxin transporters and binding proteins at a glance.
Journal of Cell Science. 128(1), 1–7.
mla: Grones, Peter, and Jiří Friml. “Auxin Transporters and Binding Proteins at
a Glance.” Journal of Cell Science, vol. 128, no. 1, Company of Biologists,
2015, pp. 1–7, doi:10.1242/jcs.159418.
short: P. Grones, J. Friml, Journal of Cell Science 128 (2015) 1–7.
date_created: 2018-12-11T11:54:28Z
date_published: 2015-01-01T00:00:00Z
date_updated: 2021-01-12T06:53:45Z
day: '01'
ddc:
- '570'
department:
- _id: JiFr
doi: 10.1242/jcs.159418
file:
- access_level: open_access
checksum: 24c779f4cd9d549ca6833e26f486be27
content_type: application/pdf
creator: system
date_created: 2018-12-12T10:11:00Z
date_updated: 2020-07-14T12:45:19Z
file_id: '4852'
file_name: IST-2016-563-v1+1_1.full.pdf
file_size: 1688844
relation: main_file
file_date_updated: 2020-07-14T12:45:19Z
has_accepted_license: '1'
intvolume: ' 128'
issue: '1'
language:
- iso: eng
month: '01'
oa: 1
oa_version: Submitted Version
page: 1 - 7
publication: Journal of Cell Science
publication_status: published
publisher: Company of Biologists
publist_id: '5225'
pubrep_id: '563'
quality_controlled: '1'
scopus_import: 1
status: public
title: Auxin transporters and binding proteins at a glance
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 128
year: '2015'
...
---
_id: '1874'
abstract:
- lang: eng
text: 'The hippocampal region, comprising the hippocampal formation and the parahippocampal
region, has been one of the most intensively studied parts of the brain for decades.
Better understanding of its functional diversity and complexity has led to an
increased demand for specificity in experimental procedures and manipulations.
In view of the complex 3D structure of the hippocampal region, precisely positioned
experimental approaches require a fine-grained architectural description that
is available and readable to experimentalists lacking detailed anatomical experience.
In this paper, we provide the first cyto- and chemoarchitectural description of
the hippocampal formation and parahippocampal region in the rat at high resolution
and in the three standard sectional planes: coronal, horizontal and sagittal.
The atlas uses a series of adjacent sections stained for neurons and for a number
of chemical marker substances, particularly parvalbumin and calbindin. All the
borders defined in one plane have been cross-checked against their counterparts
in the other two planes. The entire dataset will be made available as a web-based
interactive application through the Rodent Brain WorkBench (http://www.rbwb.org)
which, together with this paper, provides a unique atlas resource.'
author:
- first_name: Charlotte
full_name: Boccara, Charlotte
id: 3FC06552-F248-11E8-B48F-1D18A9856A87
last_name: Boccara
orcid: 0000-0001-7237-5109
- first_name: Lisa
full_name: Kjønigsen, Lisa
last_name: Kjønigsen
- first_name: Ingvild
full_name: Hammer, Ingvild
last_name: Hammer
- first_name: Jan
full_name: Bjaalie, Jan
last_name: Bjaalie
- first_name: Trygve
full_name: Leergaard, Trygve
last_name: Leergaard
- first_name: Menno
full_name: Witter, Menno
last_name: Witter
citation:
ama: Boccara CN, Kjønigsen L, Hammer I, Bjaalie J, Leergaard T, Witter M. A three-plane
architectonic atlas of the rat hippocampal region. Hippocampus. 2015;25(7):838-857.
doi:10.1002/hipo.22407
apa: Boccara, C. N., Kjønigsen, L., Hammer, I., Bjaalie, J., Leergaard, T., &
Witter, M. (2015). A three-plane architectonic atlas of the rat hippocampal region.
Hippocampus. Wiley. https://doi.org/10.1002/hipo.22407
chicago: Boccara, Charlotte N., Lisa Kjønigsen, Ingvild Hammer, Jan Bjaalie, Trygve
Leergaard, and Menno Witter. “A Three-Plane Architectonic Atlas of the Rat Hippocampal
Region.” Hippocampus. Wiley, 2015. https://doi.org/10.1002/hipo.22407.
ieee: C. N. Boccara, L. Kjønigsen, I. Hammer, J. Bjaalie, T. Leergaard, and M. Witter,
“A three-plane architectonic atlas of the rat hippocampal region,” Hippocampus,
vol. 25, no. 7. Wiley, pp. 838–857, 2015.
ista: Boccara CN, Kjønigsen L, Hammer I, Bjaalie J, Leergaard T, Witter M. 2015.
A three-plane architectonic atlas of the rat hippocampal region. Hippocampus.
25(7), 838–857.
mla: Boccara, Charlotte N., et al. “A Three-Plane Architectonic Atlas of the Rat
Hippocampal Region.” Hippocampus, vol. 25, no. 7, Wiley, 2015, pp. 838–57,
doi:10.1002/hipo.22407.
short: C.N. Boccara, L. Kjønigsen, I. Hammer, J. Bjaalie, T. Leergaard, M. Witter,
Hippocampus 25 (2015) 838–857.
date_created: 2018-12-11T11:54:29Z
date_published: 2015-07-01T00:00:00Z
date_updated: 2021-01-12T06:53:46Z
day: '01'
department:
- _id: JoCs
doi: 10.1002/hipo.22407
intvolume: ' 25'
issue: '7'
language:
- iso: eng
month: '07'
oa_version: None
page: 838 - 857
publication: Hippocampus
publication_status: published
publisher: Wiley
publist_id: '5222'
quality_controlled: '1'
scopus_import: 1
status: public
title: A three-plane architectonic atlas of the rat hippocampal region
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 25
year: '2015'
...