---
_id: '8697'
abstract:
- lang: eng
text: In the computation of the material properties of random alloys, the method
of 'special quasirandom structures' attempts to approximate the properties of
the alloy on a finite volume with higher accuracy by replicating certain statistics
of the random atomic lattice in the finite volume as accurately as possible. In
the present work, we provide a rigorous justification for a variant of this method
in the framework of the Thomas–Fermi–von Weizsäcker (TFW) model. Our approach
is based on a recent analysis of a related variance reduction method in stochastic
homogenization of linear elliptic PDEs and the locality properties of the TFW
model. Concerning the latter, we extend an exponential locality result by Nazar
and Ortner to include point charges, a result that may be of independent interest.
article_processing_charge: Yes (via OA deal)
article_type: original
author:
- first_name: Julian L
full_name: Fischer, Julian L
id: 2C12A0B0-F248-11E8-B48F-1D18A9856A87
last_name: Fischer
orcid: 0000-0002-0479-558X
- first_name: Michael
full_name: Kniely, Michael
id: 2CA2C08C-F248-11E8-B48F-1D18A9856A87
last_name: Kniely
orcid: 0000-0001-5645-4333
citation:
ama: Fischer JL, Kniely M. Variance reduction for effective energies of random lattices
in the Thomas-Fermi-von Weizsäcker model. Nonlinearity. 2020;33(11):5733-5772.
doi:10.1088/1361-6544/ab9728
apa: Fischer, J. L., & Kniely, M. (2020). Variance reduction for effective energies
of random lattices in the Thomas-Fermi-von Weizsäcker model. Nonlinearity.
IOP Publishing. https://doi.org/10.1088/1361-6544/ab9728
chicago: Fischer, Julian L, and Michael Kniely. “Variance Reduction for Effective
Energies of Random Lattices in the Thomas-Fermi-von Weizsäcker Model.” Nonlinearity.
IOP Publishing, 2020. https://doi.org/10.1088/1361-6544/ab9728.
ieee: J. L. Fischer and M. Kniely, “Variance reduction for effective energies of
random lattices in the Thomas-Fermi-von Weizsäcker model,” Nonlinearity,
vol. 33, no. 11. IOP Publishing, pp. 5733–5772, 2020.
ista: Fischer JL, Kniely M. 2020. Variance reduction for effective energies of random
lattices in the Thomas-Fermi-von Weizsäcker model. Nonlinearity. 33(11), 5733–5772.
mla: Fischer, Julian L., and Michael Kniely. “Variance Reduction for Effective Energies
of Random Lattices in the Thomas-Fermi-von Weizsäcker Model.” Nonlinearity,
vol. 33, no. 11, IOP Publishing, 2020, pp. 5733–72, doi:10.1088/1361-6544/ab9728.
short: J.L. Fischer, M. Kniely, Nonlinearity 33 (2020) 5733–5772.
date_created: 2020-10-25T23:01:16Z
date_published: 2020-11-01T00:00:00Z
date_updated: 2023-08-22T10:38:38Z
day: '01'
ddc:
- '510'
department:
- _id: JuFi
doi: 10.1088/1361-6544/ab9728
external_id:
arxiv:
- '1906.12245'
isi:
- '000576492700001'
file:
- access_level: open_access
checksum: ed90bc6eb5f32ee6157fef7f3aabc057
content_type: application/pdf
creator: cziletti
date_created: 2020-10-27T12:09:57Z
date_updated: 2020-10-27T12:09:57Z
file_id: '8710'
file_name: 2020_Nonlinearity_Fischer.pdf
file_size: 1223899
relation: main_file
success: 1
file_date_updated: 2020-10-27T12:09:57Z
has_accepted_license: '1'
intvolume: ' 33'
isi: 1
issue: '11'
language:
- iso: eng
license: https://creativecommons.org/licenses/by/3.0/
month: '11'
oa: 1
oa_version: Published Version
page: 5733-5772
publication: Nonlinearity
publication_identifier:
eissn:
- '13616544'
issn:
- '09517715'
publication_status: published
publisher: IOP Publishing
quality_controlled: '1'
scopus_import: '1'
status: public
title: Variance reduction for effective energies of random lattices in the Thomas-Fermi-von
Weizsäcker model
tmp:
image: /images/cc_by.png
legal_code_url: https://creativecommons.org/licenses/by/3.0/legalcode
name: Creative Commons Attribution 3.0 Unported (CC BY 3.0)
short: CC BY (3.0)
type: journal_article
user_id: 4359f0d1-fa6c-11eb-b949-802e58b17ae8
volume: 33
year: '2020'
...
---
_id: '8680'
abstract:
- lang: eng
text: Animal development entails the organization of specific cell types in space
and time, and spatial patterns must form in a robust manner. In the zebrafish
spinal cord, neural progenitors form stereotypic patterns despite noisy morphogen
signaling and large-scale cellular rearrangements during morphogenesis and growth.
By directly measuring adhesion forces and preferences for three types of endogenous
neural progenitors, we provide evidence for the differential adhesion model in
which differences in intercellular adhesion mediate cell sorting. Cell type–specific
combinatorial expression of different classes of cadherins (N-cadherin, cadherin
11, and protocadherin 19) results in homotypic preference ex vivo and patterning
robustness in vivo. Furthermore, the differential adhesion code is regulated by
the sonic hedgehog morphogen gradient. We propose that robust patterning during
tissue morphogenesis results from interplay between adhesion-based self-organization
and morphogen-directed patterning.
acknowledgement: "We thank the members of the Megason and Heisenberg labs for critical
discussions of and technical assistance during the work and B. Appel, S. Holley,
J. Jontes, and D. Gilmour for transgenic fish. This work is supported by the Damon
Runyon Cancer Foundation, a NICHD K99 fellowship (1K99HD092623), a Travelling Fellowship
of the Company of Biologists, a Collaborative Research grant from the Burroughs
Wellcome Foundation (T.Y.-C.T.), NIH grant 01GM107733 (T.Y.-C.T. and S.G.M.), NIH
grant R01NS102322 (T.C.-C. and H.K.), and an ERC advanced grant\r\n(MECSPEC) (C.-P.H.)."
article_processing_charge: No
article_type: original
author:
- first_name: Tony Y.-C.
full_name: Tsai, Tony Y.-C.
last_name: Tsai
- first_name: Mateusz K
full_name: Sikora, Mateusz K
id: 2F74BCDE-F248-11E8-B48F-1D18A9856A87
last_name: Sikora
- first_name: Peng
full_name: Xia, Peng
id: 4AB6C7D0-F248-11E8-B48F-1D18A9856A87
last_name: Xia
orcid: 0000-0002-5419-7756
- first_name: Tugba
full_name: Colak-Champollion, Tugba
last_name: Colak-Champollion
- first_name: Holger
full_name: Knaut, Holger
last_name: Knaut
- first_name: Carl-Philipp J
full_name: Heisenberg, Carl-Philipp J
id: 39427864-F248-11E8-B48F-1D18A9856A87
last_name: Heisenberg
orcid: 0000-0002-0912-4566
- first_name: Sean G.
full_name: Megason, Sean G.
last_name: Megason
citation:
ama: Tsai TY-C, Sikora MK, Xia P, et al. An adhesion code ensures robust pattern
formation during tissue morphogenesis. Science. 2020;370(6512):113-116.
doi:10.1126/science.aba6637
apa: Tsai, T. Y.-C., Sikora, M. K., Xia, P., Colak-Champollion, T., Knaut, H., Heisenberg,
C.-P. J., & Megason, S. G. (2020). An adhesion code ensures robust pattern
formation during tissue morphogenesis. Science. American Association for
the Advancement of Science. https://doi.org/10.1126/science.aba6637
chicago: Tsai, Tony Y.-C., Mateusz K Sikora, Peng Xia, Tugba Colak-Champollion,
Holger Knaut, Carl-Philipp J Heisenberg, and Sean G. Megason. “An Adhesion Code
Ensures Robust Pattern Formation during Tissue Morphogenesis.” Science.
American Association for the Advancement of Science, 2020. https://doi.org/10.1126/science.aba6637.
ieee: T. Y.-C. Tsai et al., “An adhesion code ensures robust pattern formation
during tissue morphogenesis,” Science, vol. 370, no. 6512. American Association
for the Advancement of Science, pp. 113–116, 2020.
ista: Tsai TY-C, Sikora MK, Xia P, Colak-Champollion T, Knaut H, Heisenberg C-PJ,
Megason SG. 2020. An adhesion code ensures robust pattern formation during tissue
morphogenesis. Science. 370(6512), 113–116.
mla: Tsai, Tony Y. C., et al. “An Adhesion Code Ensures Robust Pattern Formation
during Tissue Morphogenesis.” Science, vol. 370, no. 6512, American Association
for the Advancement of Science, 2020, pp. 113–16, doi:10.1126/science.aba6637.
short: T.Y.-C. Tsai, M.K. Sikora, P. Xia, T. Colak-Champollion, H. Knaut, C.-P.J.
Heisenberg, S.G. Megason, Science 370 (2020) 113–116.
date_created: 2020-10-19T14:09:38Z
date_published: 2020-10-02T00:00:00Z
date_updated: 2023-08-22T10:36:35Z
day: '02'
department:
- _id: CaHe
doi: 10.1126/science.aba6637
ec_funded: 1
external_id:
isi:
- '000579169000053'
intvolume: ' 370'
isi: 1
issue: '6512'
keyword:
- Multidisciplinary
language:
- iso: eng
main_file_link:
- open_access: '1'
url: https://www.biorxiv.org/content/10.1101/803635v1
month: '10'
oa: 1
oa_version: Preprint
page: 113-116
project:
- _id: 260F1432-B435-11E9-9278-68D0E5697425
call_identifier: H2020
grant_number: '742573'
name: Interaction and feedback between cell mechanics and fate specification in
vertebrate gastrulation
publication: Science
publication_identifier:
eissn:
- 1095-9203
issn:
- 0036-8075
publication_status: published
publisher: American Association for the Advancement of Science
quality_controlled: '1'
related_material:
link:
- description: News on IST Homepage
relation: press_release
url: https://ist.ac.at/en/news/sticking-together/
scopus_import: '1'
status: public
title: An adhesion code ensures robust pattern formation during tissue morphogenesis
type: journal_article
user_id: 4359f0d1-fa6c-11eb-b949-802e58b17ae8
volume: 370
year: '2020'
...
---
_id: '8707'
abstract:
- lang: eng
text: Dynamic changes in the three-dimensional (3D) organization of chromatin are
associated with central biological processes, such as transcription, replication
and development. Therefore, the comprehensive identification and quantification
of these changes is fundamental to understanding of evolutionary and regulatory
mechanisms. Here, we present Comparison of Hi-C Experiments using Structural Similarity
(CHESS), an algorithm for the comparison of chromatin contact maps and automatic
differential feature extraction. We demonstrate the robustness of CHESS to experimental
variability and showcase its biological applications on (1) interspecies comparisons
of syntenic regions in human and mouse models; (2) intraspecies identification
of conformational changes in Zelda-depleted Drosophila embryos; (3) patient-specific
aberrant chromatin conformation in a diffuse large B-cell lymphoma sample; and
(4) the systematic identification of chromatin contact differences in high-resolution
Capture-C data. In summary, CHESS is a computationally efficient method for the
comparison and classification of changes in chromatin contact data.
acknowledgement: 'Work in the Vaquerizas laboratory is funded by the Max Planck Society,
the Deutsche Forschungsgemeinschaft (DFG) Priority Programme SPP 2202 ‘Spatial Genome
Architecture in Development and Disease’ (project no. 422857230 to J.M.V.), the
DFG Clinical Research Unit CRU326 ‘Male Germ Cells: from Genes to Function’ (project
no. 329621271 to J.M.V.), the European Union’s Horizon 2020 research and innovation
programme under the Marie Skłodowska-Curie grant agreement no. 643062—ZENCODE-ITN
to J.M.V.) and the Medical Research Council in the UK. This research was partially
funded by the European Union’s H2020 Framework Programme through the European Research
Council (grant no. 609989 to M.A.M.-R.). We thank the support of the Spanish Ministerio
de Ciencia, Innovación y Universidades through grant no. BFU2017-85926-P to M.A.M.-R.
The Centre for Genomic Regulation thanks the support of the Ministerio de Ciencia,
Innovación y Universidades to the European Molecular Biology Laboratory partnership,
the ‘Centro de Excelencia Severo Ochoa 2013–2017’, agreement no. SEV-2012-0208,
the CERCA Programme/Generalitat de Catalunya, Spanish Ministerio de Ciencia, Innovación
y Universidades through the Instituto de Salud Carlos III, the Generalitat de Catalunya
through the Departament de Salut and Departament d’Empresa i Coneixement and cofinancing
by the Spanish Ministerio de Ciencia, Innovación y Universidades with funds from
the European Regional Development Fund corresponding to the 2014–2020 Smart Growth
Operating Program. S.G. thanks the support from the Company of Biologists (grant
no. JCSTF181158) and the European Molecular Biology Organization Short-Term Fellowship
programme.'
article_processing_charge: No
article_type: original
author:
- first_name: Silvia
full_name: ' Galan, Silvia'
last_name: ' Galan'
- first_name: Nick N
full_name: Machnik, Nick N
id: 3591A0AA-F248-11E8-B48F-1D18A9856A87
last_name: Machnik
orcid: 0000-0001-6617-9742
- first_name: Kai
full_name: Kruse, Kai
last_name: Kruse
- first_name: Noelia
full_name: Díaz, Noelia
last_name: Díaz
- first_name: Marc A
full_name: Marti-Renom, Marc A
last_name: Marti-Renom
- first_name: Juan M
full_name: Vaquerizas, Juan M
last_name: Vaquerizas
citation:
ama: Galan S, Machnik NN, Kruse K, Díaz N, Marti-Renom MA, Vaquerizas JM. CHESS
enables quantitative comparison of chromatin contact data and automatic feature
extraction. Nature Genetics. 2020;52:1247-1255. doi:10.1038/s41588-020-00712-y
apa: Galan, S., Machnik, N. N., Kruse, K., Díaz, N., Marti-Renom, M. A., & Vaquerizas,
J. M. (2020). CHESS enables quantitative comparison of chromatin contact data
and automatic feature extraction. Nature Genetics. Springer Nature. https://doi.org/10.1038/s41588-020-00712-y
chicago: Galan, Silvia, Nick N Machnik, Kai Kruse, Noelia Díaz, Marc A Marti-Renom,
and Juan M Vaquerizas. “CHESS Enables Quantitative Comparison of Chromatin Contact
Data and Automatic Feature Extraction.” Nature Genetics. Springer Nature,
2020. https://doi.org/10.1038/s41588-020-00712-y.
ieee: S. Galan, N. N. Machnik, K. Kruse, N. Díaz, M. A. Marti-Renom, and J. M.
Vaquerizas, “CHESS enables quantitative comparison of chromatin contact data and
automatic feature extraction,” Nature Genetics, vol. 52. Springer Nature,
pp. 1247–1255, 2020.
ista: Galan S, Machnik NN, Kruse K, Díaz N, Marti-Renom MA, Vaquerizas JM. 2020.
CHESS enables quantitative comparison of chromatin contact data and automatic
feature extraction. Nature Genetics. 52, 1247–1255.
mla: Galan, Silvia, et al. “CHESS Enables Quantitative Comparison of Chromatin Contact
Data and Automatic Feature Extraction.” Nature Genetics, vol. 52, Springer
Nature, 2020, pp. 1247–55, doi:10.1038/s41588-020-00712-y.
short: S. Galan, N.N. Machnik, K. Kruse, N. Díaz, M.A. Marti-Renom, J.M. Vaquerizas,
Nature Genetics 52 (2020) 1247–1255.
date_created: 2020-10-25T23:01:20Z
date_published: 2020-10-19T00:00:00Z
date_updated: 2023-08-22T10:37:10Z
day: '19'
department:
- _id: FyKo
doi: 10.1038/s41588-020-00712-y
external_id:
isi:
- '000579693500004'
pmid:
- '33077914'
intvolume: ' 52'
isi: 1
language:
- iso: eng
month: '10'
oa_version: None
page: 1247-1255
pmid: 1
publication: Nature Genetics
publication_identifier:
eissn:
- '15461718'
issn:
- '10614036'
publication_status: published
publisher: Springer Nature
quality_controlled: '1'
scopus_import: '1'
status: public
title: CHESS enables quantitative comparison of chromatin contact data and automatic
feature extraction
type: journal_article
user_id: 4359f0d1-fa6c-11eb-b949-802e58b17ae8
volume: 52
year: '2020'
...
---
_id: '8679'
abstract:
- lang: eng
text: A central goal of artificial intelligence in high-stakes decision-making applications
is to design a single algorithm that simultaneously expresses generalizability
by learning coherent representations of their world and interpretable explanations
of its dynamics. Here, we combine brain-inspired neural computation principles
and scalable deep learning architectures to design compact neural controllers
for task-specific compartments of a full-stack autonomous vehicle control system.
We discover that a single algorithm with 19 control neurons, connecting 32 encapsulated
input features to outputs by 253 synapses, learns to map high-dimensional inputs
into steering commands. This system shows superior generalizability, interpretability
and robustness compared with orders-of-magnitude larger black-box learning systems.
The obtained neural agents enable high-fidelity autonomy for task-specific parts
of a complex autonomous system.
article_processing_charge: No
article_type: original
author:
- first_name: Mathias
full_name: Lechner, Mathias
id: 3DC22916-F248-11E8-B48F-1D18A9856A87
last_name: Lechner
- first_name: Ramin
full_name: Hasani, Ramin
last_name: Hasani
- first_name: Alexander
full_name: Amini, Alexander
last_name: Amini
- first_name: Thomas A
full_name: Henzinger, Thomas A
id: 40876CD8-F248-11E8-B48F-1D18A9856A87
last_name: Henzinger
orcid: 0000-0002-2985-7724
- first_name: Daniela
full_name: Rus, Daniela
last_name: Rus
- first_name: Radu
full_name: Grosu, Radu
last_name: Grosu
citation:
ama: Lechner M, Hasani R, Amini A, Henzinger TA, Rus D, Grosu R. Neural circuit
policies enabling auditable autonomy. Nature Machine Intelligence. 2020;2:642-652.
doi:10.1038/s42256-020-00237-3
apa: Lechner, M., Hasani, R., Amini, A., Henzinger, T. A., Rus, D., & Grosu,
R. (2020). Neural circuit policies enabling auditable autonomy. Nature Machine
Intelligence. Springer Nature. https://doi.org/10.1038/s42256-020-00237-3
chicago: Lechner, Mathias, Ramin Hasani, Alexander Amini, Thomas A Henzinger, Daniela
Rus, and Radu Grosu. “Neural Circuit Policies Enabling Auditable Autonomy.” Nature
Machine Intelligence. Springer Nature, 2020. https://doi.org/10.1038/s42256-020-00237-3.
ieee: M. Lechner, R. Hasani, A. Amini, T. A. Henzinger, D. Rus, and R. Grosu, “Neural
circuit policies enabling auditable autonomy,” Nature Machine Intelligence,
vol. 2. Springer Nature, pp. 642–652, 2020.
ista: Lechner M, Hasani R, Amini A, Henzinger TA, Rus D, Grosu R. 2020. Neural circuit
policies enabling auditable autonomy. Nature Machine Intelligence. 2, 642–652.
mla: Lechner, Mathias, et al. “Neural Circuit Policies Enabling Auditable Autonomy.”
Nature Machine Intelligence, vol. 2, Springer Nature, 2020, pp. 642–52,
doi:10.1038/s42256-020-00237-3.
short: M. Lechner, R. Hasani, A. Amini, T.A. Henzinger, D. Rus, R. Grosu, Nature
Machine Intelligence 2 (2020) 642–652.
date_created: 2020-10-19T13:46:06Z
date_published: 2020-10-01T00:00:00Z
date_updated: 2023-08-22T10:36:06Z
day: '01'
department:
- _id: ToHe
doi: 10.1038/s42256-020-00237-3
external_id:
isi:
- '000583337200011'
intvolume: ' 2'
isi: 1
language:
- iso: eng
month: '10'
oa_version: None
page: 642-652
project:
- _id: 25F42A32-B435-11E9-9278-68D0E5697425
call_identifier: FWF
grant_number: Z211
name: The Wittgenstein Prize
publication: Nature Machine Intelligence
publication_identifier:
eissn:
- 2522-5839
publication_status: published
publisher: Springer Nature
quality_controlled: '1'
related_material:
link:
- description: News on IST Homepage
relation: press_release
url: https://ist.ac.at/en/news/new-deep-learning-models/
scopus_import: '1'
status: public
title: Neural circuit policies enabling auditable autonomy
type: journal_article
user_id: 4359f0d1-fa6c-11eb-b949-802e58b17ae8
volume: 2
year: '2020'
...
---
_id: '8670'
abstract:
- lang: eng
text: The α–z Rényi relative entropies are a two-parameter family of Rényi relative
entropies that are quantum generalizations of the classical α-Rényi relative entropies.
In the work [Adv. Math. 365, 107053 (2020)], we decided the full range of (α,
z) for which the data processing inequality (DPI) is valid. In this paper, we
give algebraic conditions for the equality in DPI. For the full range of parameters
(α, z), we give necessary conditions and sufficient conditions. For most parameters,
we give equivalent conditions. This generalizes and strengthens the results of
Leditzky et al. [Lett. Math. Phys. 107, 61–80 (2017)].
acknowledgement: This research was supported by the European Union’s Horizon 2020
research and innovation program under the Marie Skłodowska-Curie Grant Agreement
No. 754411. The author would like to thank Anna Vershynina and Sarah Chehade for
their helpful comments.
article_number: '102201'
article_processing_charge: No
article_type: original
author:
- first_name: Haonan
full_name: Zhang, Haonan
id: D8F41E38-9E66-11E9-A9E2-65C2E5697425
last_name: Zhang
citation:
ama: Zhang H. Equality conditions of data processing inequality for α-z Rényi relative
entropies. Journal of Mathematical Physics. 2020;61(10). doi:10.1063/5.0022787
apa: Zhang, H. (2020). Equality conditions of data processing inequality for α-z
Rényi relative entropies. Journal of Mathematical Physics. AIP Publishing.
https://doi.org/10.1063/5.0022787
chicago: Zhang, Haonan. “Equality Conditions of Data Processing Inequality for α-z
Rényi Relative Entropies.” Journal of Mathematical Physics. AIP Publishing,
2020. https://doi.org/10.1063/5.0022787.
ieee: H. Zhang, “Equality conditions of data processing inequality for α-z Rényi
relative entropies,” Journal of Mathematical Physics, vol. 61, no. 10.
AIP Publishing, 2020.
ista: Zhang H. 2020. Equality conditions of data processing inequality for α-z Rényi
relative entropies. Journal of Mathematical Physics. 61(10), 102201.
mla: Zhang, Haonan. “Equality Conditions of Data Processing Inequality for α-z Rényi
Relative Entropies.” Journal of Mathematical Physics, vol. 61, no. 10,
102201, AIP Publishing, 2020, doi:10.1063/5.0022787.
short: H. Zhang, Journal of Mathematical Physics 61 (2020).
date_created: 2020-10-18T22:01:36Z
date_published: 2020-10-01T00:00:00Z
date_updated: 2023-08-22T10:32:29Z
day: '01'
department:
- _id: JaMa
doi: 10.1063/5.0022787
ec_funded: 1
external_id:
arxiv:
- '2007.06644'
isi:
- '000578529200001'
intvolume: ' 61'
isi: 1
issue: '10'
language:
- iso: eng
main_file_link:
- open_access: '1'
url: https://arxiv.org/abs/2007.06644
month: '10'
oa: 1
oa_version: Preprint
project:
- _id: 260C2330-B435-11E9-9278-68D0E5697425
call_identifier: H2020
grant_number: '754411'
name: ISTplus - Postdoctoral Fellowships
publication: Journal of Mathematical Physics
publication_identifier:
issn:
- '00222488'
publication_status: published
publisher: AIP Publishing
quality_controlled: '1'
scopus_import: '1'
status: public
title: Equality conditions of data processing inequality for α-z Rényi relative entropies
type: journal_article
user_id: 4359f0d1-fa6c-11eb-b949-802e58b17ae8
volume: 61
year: '2020'
...
---
_id: '8698'
abstract:
- lang: eng
text: The brain represents and reasons probabilistically about complex stimuli and
motor actions using a noisy, spike-based neural code. A key building block for
such neural computations, as well as the basis for supervised and unsupervised
learning, is the ability to estimate the surprise or likelihood of incoming high-dimensional
neural activity patterns. Despite progress in statistical modeling of neural responses
and deep learning, current approaches either do not scale to large neural populations
or cannot be implemented using biologically realistic mechanisms. Inspired by
the sparse and random connectivity of real neuronal circuits, we present a model
for neural codes that accurately estimates the likelihood of individual spiking
patterns and has a straightforward, scalable, efficient, learnable, and realistic
neural implementation. This model’s performance on simultaneously recorded spiking
activity of >100 neurons in the monkey visual and prefrontal cortices is comparable
with or better than that of state-of-the-art models. Importantly, the model can
be learned using a small number of samples and using a local learning rule that
utilizes noise intrinsic to neural circuits. Slower, structural changes in random
connectivity, consistent with rewiring and pruning processes, further improve
the efficiency and sparseness of the resulting neural representations. Our results
merge insights from neuroanatomy, machine learning, and theoretical neuroscience
to suggest random sparse connectivity as a key design principle for neuronal computation.
acknowledgement: We thank Udi Karpas, Roy Harpaz, Tal Tamir, Adam Haber, and Amir
Bar for discussions and suggestions; and especially Oren Forkosh and Walter Senn
for invaluable discussions of the learning rule. This work was supported by European
Research Council Grant 311238 (to E.S.) and Israel Science Foundation Grant 1629/12
(to E.S.); as well as research support from Martin Kushner Schnur and Mr. and Mrs.
Lawrence Feis (E.S.); National Institute of Mental Health Grant R01MH109180 (to
R.K.); a Pew Scholarship in Biomedical Sciences (to R.K.); Simons Collaboration
on the Global Brain Grant 542997 (to R.K. and E.S.); and a CRCNS (Collaborative
Research in Computational Neuroscience) grant (to R.K. and E.S.).
article_processing_charge: No
article_type: original
author:
- first_name: Ori
full_name: Maoz, Ori
last_name: Maoz
- first_name: Gašper
full_name: Tkačik, Gašper
id: 3D494DCA-F248-11E8-B48F-1D18A9856A87
last_name: Tkačik
orcid: 0000-0002-6699-1455
- first_name: Mohamad Saleh
full_name: Esteki, Mohamad Saleh
last_name: Esteki
- first_name: Roozbeh
full_name: Kiani, Roozbeh
last_name: Kiani
- first_name: Elad
full_name: Schneidman, Elad
last_name: Schneidman
citation:
ama: Maoz O, Tkačik G, Esteki MS, Kiani R, Schneidman E. Learning probabilistic
neural representations with randomly connected circuits. Proceedings of the
National Academy of Sciences of the United States of America. 2020;117(40):25066-25073.
doi:10.1073/pnas.1912804117
apa: Maoz, O., Tkačik, G., Esteki, M. S., Kiani, R., & Schneidman, E. (2020).
Learning probabilistic neural representations with randomly connected circuits.
Proceedings of the National Academy of Sciences of the United States of America.
National Academy of Sciences. https://doi.org/10.1073/pnas.1912804117
chicago: Maoz, Ori, Gašper Tkačik, Mohamad Saleh Esteki, Roozbeh Kiani, and Elad
Schneidman. “Learning Probabilistic Neural Representations with Randomly Connected
Circuits.” Proceedings of the National Academy of Sciences of the United States
of America. National Academy of Sciences, 2020. https://doi.org/10.1073/pnas.1912804117.
ieee: O. Maoz, G. Tkačik, M. S. Esteki, R. Kiani, and E. Schneidman, “Learning probabilistic
neural representations with randomly connected circuits,” Proceedings of the
National Academy of Sciences of the United States of America, vol. 117, no.
40. National Academy of Sciences, pp. 25066–25073, 2020.
ista: Maoz O, Tkačik G, Esteki MS, Kiani R, Schneidman E. 2020. Learning probabilistic
neural representations with randomly connected circuits. Proceedings of the National
Academy of Sciences of the United States of America. 117(40), 25066–25073.
mla: Maoz, Ori, et al. “Learning Probabilistic Neural Representations with Randomly
Connected Circuits.” Proceedings of the National Academy of Sciences of the
United States of America, vol. 117, no. 40, National Academy of Sciences,
2020, pp. 25066–73, doi:10.1073/pnas.1912804117.
short: O. Maoz, G. Tkačik, M.S. Esteki, R. Kiani, E. Schneidman, Proceedings of
the National Academy of Sciences of the United States of America 117 (2020) 25066–25073.
date_created: 2020-10-25T23:01:16Z
date_published: 2020-10-06T00:00:00Z
date_updated: 2023-08-22T12:11:23Z
day: '06'
ddc:
- '570'
department:
- _id: GaTk
doi: 10.1073/pnas.1912804117
external_id:
isi:
- '000579045200012'
pmid:
- '32948691'
file:
- access_level: open_access
checksum: c6a24fdecf3f28faf447078e7a274a88
content_type: application/pdf
creator: cziletti
date_created: 2020-10-27T14:57:50Z
date_updated: 2020-10-27T14:57:50Z
file_id: '8713'
file_name: 2020_PNAS_Maoz.pdf
file_size: 1755359
relation: main_file
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issue: '40'
language:
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license: https://creativecommons.org/licenses/by-nc-nd/4.0/
month: '10'
oa: 1
oa_version: Published Version
page: 25066-25073
pmid: 1
publication: Proceedings of the National Academy of Sciences of the United States
of America
publication_identifier:
eissn:
- '10916490'
issn:
- '00278424'
publication_status: published
publisher: National Academy of Sciences
quality_controlled: '1'
scopus_import: '1'
status: public
title: Learning probabilistic neural representations with randomly connected circuits
tmp:
image: /images/cc_by_nc_nd.png
legal_code_url: https://creativecommons.org/licenses/by-nc-nd/4.0/legalcode
name: Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International
(CC BY-NC-ND 4.0)
short: CC BY-NC-ND (4.0)
type: journal_article
user_id: 4359f0d1-fa6c-11eb-b949-802e58b17ae8
volume: 117
year: '2020'
...
---
_id: '8704'
abstract:
- lang: eng
text: Traditional robotic control suits require profound task-specific knowledge
for designing, building and testing control software. The rise of Deep Learning
has enabled end-to-end solutions to be learned entirely from data, requiring minimal
knowledge about the application area. We design a learning scheme to train end-to-end
linear dynamical systems (LDS)s by gradient descent in imitation learning robotic
domains. We introduce a new regularization loss component together with a learning
algorithm that improves the stability of the learned autonomous system, by forcing
the eigenvalues of the internal state updates of an LDS to be negative reals.
We evaluate our approach on a series of real-life and simulated robotic experiments,
in comparison to linear and nonlinear Recurrent Neural Network (RNN) architectures.
Our results show that our stabilizing method significantly improves test performance
of LDS, enabling such linear models to match the performance of contemporary nonlinear
RNN architectures. A video of the obstacle avoidance performance of our method
on a mobile robot, in unseen environments, compared to other methods can be viewed
at https://youtu.be/mhEsCoNao5E.
acknowledgement: M.L. is supported in parts by the Austrian Science Fund (FWF) under
grant Z211-N23 (Wittgenstein Award). R.H., and R.G. are partially supported by the
Horizon-2020 ECSELProject grant No. 783163 (iDev40), and the Austrian Research Promotion
Agency (FFG), Project No. 860424. R.H. and D.R. is partially supported by the Boeing
Company.
alternative_title:
- ICRA
article_processing_charge: No
author:
- first_name: Mathias
full_name: Lechner, Mathias
id: 3DC22916-F248-11E8-B48F-1D18A9856A87
last_name: Lechner
- first_name: Ramin
full_name: Hasani, Ramin
last_name: Hasani
- first_name: Daniela
full_name: Rus, Daniela
last_name: Rus
- first_name: Radu
full_name: Grosu, Radu
last_name: Grosu
citation:
ama: 'Lechner M, Hasani R, Rus D, Grosu R. Gershgorin loss stabilizes the recurrent
neural network compartment of an end-to-end robot learning scheme. In: Proceedings
- IEEE International Conference on Robotics and Automation. IEEE; 2020:5446-5452.
doi:10.1109/ICRA40945.2020.9196608'
apa: 'Lechner, M., Hasani, R., Rus, D., & Grosu, R. (2020). Gershgorin loss
stabilizes the recurrent neural network compartment of an end-to-end robot learning
scheme. In Proceedings - IEEE International Conference on Robotics and Automation
(pp. 5446–5452). Paris, France: IEEE. https://doi.org/10.1109/ICRA40945.2020.9196608'
chicago: Lechner, Mathias, Ramin Hasani, Daniela Rus, and Radu Grosu. “Gershgorin
Loss Stabilizes the Recurrent Neural Network Compartment of an End-to-End Robot
Learning Scheme.” In Proceedings - IEEE International Conference on Robotics
and Automation, 5446–52. IEEE, 2020. https://doi.org/10.1109/ICRA40945.2020.9196608.
ieee: M. Lechner, R. Hasani, D. Rus, and R. Grosu, “Gershgorin loss stabilizes the
recurrent neural network compartment of an end-to-end robot learning scheme,”
in Proceedings - IEEE International Conference on Robotics and Automation,
Paris, France, 2020, pp. 5446–5452.
ista: 'Lechner M, Hasani R, Rus D, Grosu R. 2020. Gershgorin loss stabilizes the
recurrent neural network compartment of an end-to-end robot learning scheme. Proceedings
- IEEE International Conference on Robotics and Automation. ICRA: International
Conference on Robotics and Automation, ICRA, , 5446–5452.'
mla: Lechner, Mathias, et al. “Gershgorin Loss Stabilizes the Recurrent Neural Network
Compartment of an End-to-End Robot Learning Scheme.” Proceedings - IEEE International
Conference on Robotics and Automation, IEEE, 2020, pp. 5446–52, doi:10.1109/ICRA40945.2020.9196608.
short: M. Lechner, R. Hasani, D. Rus, R. Grosu, in:, Proceedings - IEEE International
Conference on Robotics and Automation, IEEE, 2020, pp. 5446–5452.
conference:
end_date: 2020-08-31
location: Paris, France
name: 'ICRA: International Conference on Robotics and Automation'
start_date: 2020-05-31
date_created: 2020-10-25T23:01:19Z
date_published: 2020-05-01T00:00:00Z
date_updated: 2023-08-22T10:40:15Z
day: '01'
ddc:
- '000'
department:
- _id: ToHe
doi: 10.1109/ICRA40945.2020.9196608
external_id:
isi:
- '000712319503110'
file:
- access_level: open_access
checksum: fccf7b986ac78046918a298cc6849a50
content_type: application/pdf
creator: dernst
date_created: 2020-11-06T10:58:49Z
date_updated: 2020-11-06T10:58:49Z
file_id: '8733'
file_name: 2020_ICRA_Lechner.pdf
file_size: 1070010
relation: main_file
success: 1
file_date_updated: 2020-11-06T10:58:49Z
has_accepted_license: '1'
isi: 1
language:
- iso: eng
month: '05'
oa: 1
oa_version: Submitted Version
page: 5446-5452
project:
- _id: 25F42A32-B435-11E9-9278-68D0E5697425
call_identifier: FWF
grant_number: Z211
name: The Wittgenstein Prize
publication: Proceedings - IEEE International Conference on Robotics and Automation
publication_identifier:
isbn:
- '9781728173955'
issn:
- '10504729'
publication_status: published
publisher: IEEE
quality_controlled: '1'
scopus_import: '1'
status: public
title: Gershgorin loss stabilizes the recurrent neural network compartment of an end-to-end
robot learning scheme
type: conference
user_id: 4359f0d1-fa6c-11eb-b949-802e58b17ae8
year: '2020'
...
---
_id: '8700'
abstract:
- lang: eng
text: Translation termination is a finishing step of protein biosynthesis. The significant
role in this process belongs not only to protein factors of translation termination
but also to the nearest nucleotide environment of stop codons. There are numerous
descriptions of stop codons readthrough, which is due to specific nucleotide sequences
behind them. However, represented data are segmental and don’t explain the mechanism
of the nucleotide context influence on translation termination. It is well known
that stop codon UAA usage is preferential for A/T-rich genes, and UAG, UGA—for
G/C-rich genes, which is related to an expression level of these genes. We investigated
the connection between a frequency of nucleotides occurrence in 3' area of stop
codons in the human genome and their influence on translation termination efficiency.
We found that 3' context motif, which is cognate to the sequence of a stop codon,
stimulates translation termination. At the same time, the nucleotide composition
of 3' sequence that differs from stop codon, decreases translation termination
efficiency.
acknowledgement: We would like to thank the staff of CCU Genome for sequencing, Tat’yana
Pestova, Christopher Helen, and Lyudmila Yur’evna Frolova for the plasmids provided,
as well as the laboratory staff for productive discussion of the results. We also
thank former laboratory employees Yuliya Vladimirovna Bocharova and Polina Nikolaevna
Kryuchkova for the exceptional contribution to the present work.
article_processing_charge: No
article_type: original
author:
- first_name: E. E.
full_name: Sokolova, E. E.
last_name: Sokolova
- first_name: Petr
full_name: Vlasov, Petr
id: 38BB9AC4-F248-11E8-B48F-1D18A9856A87
last_name: Vlasov
- first_name: T. V.
full_name: Egorova, T. V.
last_name: Egorova
- first_name: A. V.
full_name: Shuvalov, A. V.
last_name: Shuvalov
- first_name: E. Z.
full_name: Alkalaeva, E. Z.
last_name: Alkalaeva
citation:
ama: Sokolova EE, Vlasov P, Egorova TV, Shuvalov AV, Alkalaeva EZ. The influence
of A/G composition of 3’ stop codon contexts on translation termination efficiency
in eukaryotes. Molecular Biology. 2020;54(5):739-748. doi:10.1134/S0026893320050088
apa: Sokolova, E. E., Vlasov, P., Egorova, T. V., Shuvalov, A. V., & Alkalaeva,
E. Z. (2020). The influence of A/G composition of 3’ stop codon contexts on translation
termination efficiency in eukaryotes. Molecular Biology. Springer Nature.
https://doi.org/10.1134/S0026893320050088
chicago: Sokolova, E. E., Petr Vlasov, T. V. Egorova, A. V. Shuvalov, and E. Z.
Alkalaeva. “The Influence of A/G Composition of 3’ Stop Codon Contexts on Translation
Termination Efficiency in Eukaryotes.” Molecular Biology. Springer Nature,
2020. https://doi.org/10.1134/S0026893320050088.
ieee: E. E. Sokolova, P. Vlasov, T. V. Egorova, A. V. Shuvalov, and E. Z. Alkalaeva,
“The influence of A/G composition of 3’ stop codon contexts on translation termination
efficiency in eukaryotes,” Molecular Biology, vol. 54, no. 5. Springer
Nature, pp. 739–748, 2020.
ista: Sokolova EE, Vlasov P, Egorova TV, Shuvalov AV, Alkalaeva EZ. 2020. The influence
of A/G composition of 3’ stop codon contexts on translation termination efficiency
in eukaryotes. Molecular Biology. 54(5), 739–748.
mla: Sokolova, E. E., et al. “The Influence of A/G Composition of 3’ Stop Codon
Contexts on Translation Termination Efficiency in Eukaryotes.” Molecular Biology,
vol. 54, no. 5, Springer Nature, 2020, pp. 739–48, doi:10.1134/S0026893320050088.
short: E.E. Sokolova, P. Vlasov, T.V. Egorova, A.V. Shuvalov, E.Z. Alkalaeva, Molecular
Biology 54 (2020) 739–748.
date_created: 2020-10-25T23:01:17Z
date_published: 2020-09-01T00:00:00Z
date_updated: 2023-08-22T10:39:38Z
day: '01'
department:
- _id: FyKo
doi: 10.1134/S0026893320050088
external_id:
isi:
- '000579441200009'
intvolume: ' 54'
isi: 1
issue: '5'
language:
- iso: eng
month: '09'
oa_version: None
page: 739-748
publication: Molecular Biology
publication_identifier:
eissn:
- '16083245'
issn:
- '00268933'
publication_status: published
publisher: Springer Nature
quality_controlled: '1'
related_material:
record:
- id: '8701'
relation: original
status: public
scopus_import: '1'
status: public
title: The influence of A/G composition of 3' stop codon contexts on translation termination
efficiency in eukaryotes
type: journal_article
user_id: 4359f0d1-fa6c-11eb-b949-802e58b17ae8
volume: 54
year: '2020'
...
---
_id: '8701'
abstract:
- lang: eng
text: Translation termination is a finishing step of protein biosynthesis. The significant
role in this process belongs not only to protein factors of translation termination
but also to the nearest nucleotide environment of stop codons. There are numerous
descriptions of stop codons readthrough, which is due to specific nucleotide sequences
behind them. However, represented data are segmental and don’t explain the mechanism
of the nucleotide context influence on translation termination. It is well known
that stop codon UAA usage is preferential for A/T-rich genes, and UAG, UGA—for
G/C-rich genes, which is related to an expression level of these genes. We investigated
the connection between a frequency of nucleotides occurrence in 3' area of stop
codons in the human genome and their influence on translation termination efficiency.
We found that 3' context motif, which is cognate to the sequence of a stop codon,
stimulates translation termination. At the same time, the nucleotide composition
of 3' sequence that differs from stop codon, decreases translation termination
efficiency.
article_processing_charge: No
article_type: original
author:
- first_name: E. E.
full_name: Sokolova, E. E.
last_name: Sokolova
- first_name: Petr
full_name: Vlasov, Petr
id: 38BB9AC4-F248-11E8-B48F-1D18A9856A87
last_name: Vlasov
- first_name: T. V.
full_name: Egorova, T. V.
last_name: Egorova
- first_name: A. V.
full_name: Shuvalov, A. V.
last_name: Shuvalov
- first_name: E. Z.
full_name: Alkalaeva, E. Z.
last_name: Alkalaeva
citation:
ama: Sokolova EE, Vlasov P, Egorova TV, Shuvalov AV, Alkalaeva EZ. The influence
of A/G composition of 3’ stop codon contexts on translation termination efficiency
in eukaryotes. Molekuliarnaia biologiia. 2020;54(5):837-848. doi:10.31857/S0026898420050080
apa: Sokolova, E. E., Vlasov, P., Egorova, T. V., Shuvalov, A. V., & Alkalaeva,
E. Z. (2020). The influence of A/G composition of 3’ stop codon contexts on translation
termination efficiency in eukaryotes. Molekuliarnaia biologiia. Russian
Academy of Sciences. https://doi.org/10.31857/S0026898420050080
chicago: Sokolova, E. E., Petr Vlasov, T. V. Egorova, A. V. Shuvalov, and E. Z.
Alkalaeva. “The influence of A/G composition of 3’ stop codon contexts on translation
termination efficiency in eukaryotes.” Molekuliarnaia biologiia. Russian
Academy of Sciences, 2020. https://doi.org/10.31857/S0026898420050080.
ieee: E. E. Sokolova, P. Vlasov, T. V. Egorova, A. V. Shuvalov, and E. Z. Alkalaeva,
“The influence of A/G composition of 3’ stop codon contexts on translation termination
efficiency in eukaryotes,” Molekuliarnaia biologiia, vol. 54, no. 5. Russian
Academy of Sciences, pp. 837–848, 2020.
ista: Sokolova EE, Vlasov P, Egorova TV, Shuvalov AV, Alkalaeva EZ. 2020. The influence
of A/G composition of 3’ stop codon contexts on translation termination efficiency
in eukaryotes. Molekuliarnaia biologiia. 54(5), 837–848.
mla: Sokolova, E. E., et al. “The influence of A/G composition of 3’ stop codon
contexts on translation termination efficiency in eukaryotes.” Molekuliarnaia
biologiia, vol. 54, no. 5, Russian Academy of Sciences, 2020, pp. 837–48,
doi:10.31857/S0026898420050080.
short: E.E. Sokolova, P. Vlasov, T.V. Egorova, A.V. Shuvalov, E.Z. Alkalaeva, Molekuliarnaia
biologiia 54 (2020) 837–848.
date_created: 2020-10-25T23:01:17Z
date_published: 2020-09-01T00:00:00Z
date_updated: 2023-08-22T10:39:37Z
day: '01'
department:
- _id: FyKo
doi: 10.31857/S0026898420050080
external_id:
pmid:
- '33009793'
intvolume: ' 54'
issue: '5'
language:
- iso: rus
month: '09'
oa_version: None
page: 837-848
pmid: 1
publication: Molekuliarnaia biologiia
publication_identifier:
issn:
- '00268984'
publication_status: published
publisher: Russian Academy of Sciences
quality_controlled: '1'
related_material:
record:
- id: '8700'
relation: translation
status: public
scopus_import: '1'
status: public
title: The influence of A/G composition of 3' stop codon contexts on translation termination
efficiency in eukaryotes
type: journal_article
user_id: D865714E-FA4E-11E9-B85B-F5C5E5697425
volume: 54
year: '2020'
...
---
_id: '14096'
abstract:
- lang: eng
text: A binary neutron star merger has been observed in a multi-messenger detection
of gravitational wave (GW) and electromagnetic (EM) radiation. Binary neutron
stars that merge within a Hubble time, as well as many other compact binaries,
are expected to form via common envelope evolution. Yet five decades of research
on common envelope evolution have not yet resulted in a satisfactory understanding
of the multi-spatial multi-timescale evolution for the systems that lead to compact
binaries. In this paper, we report on the first successful simulations of common
envelope ejection leading to binary neutron star formation in 3D hydrodynamics.
We simulate the dynamical inspiral phase of the interaction between a 12M⊙ red
supergiant and a 1.4M⊙ neutron star for different initial separations and initial
conditions. For all of our simulations, we find complete envelope ejection and
final orbital separations of af≈1.3-5.1R⊙ depending on the simulation and criterion,
leading to binary neutron stars that can merge within a Hubble time. We find αCE-equivalent
efficiencies of ≈0.1-2.7 depending on the simulation and criterion, but this may
be specific for these extended progenitors. We fully resolve the core of the star
to ≲0.005R⊙ and our 3D hydrodynamics simulations are informed by an adjusted 1D
analytic energy formalism and a 2D kinematics study in order to overcome the prohibitive
computational cost of simulating these systems. The framework we develop in this
paper can be used to simulate a wide variety of interactions between stars, from
stellar mergers to common envelope episodes leading to GW sources.
article_number: '2011.06630'
article_processing_charge: No
author:
- first_name: Jamie A. P. Law-Smith
full_name: Jamie A. P. Law-Smith, Jamie A. P. Law-Smith
last_name: Jamie A. P. Law-Smith
- first_name: Rosa Wallace
full_name: Everson, Rosa Wallace
last_name: Everson
- first_name: Enrico Ramirez-Ruiz
full_name: Enrico Ramirez-Ruiz, Enrico Ramirez-Ruiz
last_name: Enrico Ramirez-Ruiz
- first_name: Selma E. de
full_name: Mink, Selma E. de
last_name: Mink
- first_name: Lieke A. C. van
full_name: Son, Lieke A. C. van
last_name: Son
- first_name: Ylva Louise Linsdotter
full_name: Götberg, Ylva Louise Linsdotter
id: d0648d0c-0f64-11ee-a2e0-dd0faa2e4f7d
last_name: Götberg
orcid: 0000-0002-6960-6911
- first_name: Stefan
full_name: Zellmann, Stefan
last_name: Zellmann
- first_name: Alejandro Vigna-Gómez
full_name: Alejandro Vigna-Gómez, Alejandro Vigna-Gómez
last_name: Alejandro Vigna-Gómez
- first_name: Mathieu
full_name: Renzo, Mathieu
last_name: Renzo
- first_name: Samantha
full_name: Wu, Samantha
last_name: Wu
- first_name: Sophie L.
full_name: Schrøder, Sophie L.
last_name: Schrøder
- first_name: Ryan J.
full_name: Foley, Ryan J.
last_name: Foley
- first_name: Tenley Hutchinson-Smith
full_name: Tenley Hutchinson-Smith, Tenley Hutchinson-Smith
last_name: Tenley Hutchinson-Smith
citation:
ama: Jamie A. P. Law-Smith JAPL-S, Everson RW, Enrico Ramirez-Ruiz ER-R, et al.
Successful common envelope ejection and binary neutron star formation in 3D hydrodynamics.
arXiv. doi:10.48550/arXiv.2011.06630
apa: Jamie A. P. Law-Smith, J. A. P. L.-S., Everson, R. W., Enrico Ramirez-Ruiz,
E. R.-R., Mink, S. E. de, Son, L. A. C. van, Götberg, Y. L. L., … Tenley Hutchinson-Smith,
T. H.-S. (n.d.). Successful common envelope ejection and binary neutron star formation
in 3D hydrodynamics. arXiv. https://doi.org/10.48550/arXiv.2011.06630
chicago: Jamie A. P. Law-Smith, Jamie A. P. Law-Smith, Rosa Wallace Everson, Enrico
Ramirez-Ruiz Enrico Ramirez-Ruiz, Selma E. de Mink, Lieke A. C. van Son, Ylva
Louise Linsdotter Götberg, Stefan Zellmann, et al. “Successful Common Envelope
Ejection and Binary Neutron Star Formation in 3D Hydrodynamics.” ArXiv,
n.d. https://doi.org/10.48550/arXiv.2011.06630.
ieee: J. A. P. L.-S. Jamie A. P. Law-Smith et al., “Successful common envelope
ejection and binary neutron star formation in 3D hydrodynamics,” arXiv.
.
ista: Jamie A. P. Law-Smith JAPL-S, Everson RW, Enrico Ramirez-Ruiz ER-R, Mink SE
de, Son LAC van, Götberg YLL, Zellmann S, Alejandro Vigna-Gómez AV-G, Renzo M,
Wu S, Schrøder SL, Foley RJ, Tenley Hutchinson-Smith TH-S. Successful common envelope
ejection and binary neutron star formation in 3D hydrodynamics. arXiv, 2011.06630.
mla: Jamie A. P. Law-Smith, Jamie A. P. Law-Smith, et al. “Successful Common Envelope
Ejection and Binary Neutron Star Formation in 3D Hydrodynamics.” ArXiv,
2011.06630, doi:10.48550/arXiv.2011.06630.
short: J.A.P.L.-S. Jamie A. P. Law-Smith, R.W. Everson, E.R.-R. Enrico Ramirez-Ruiz,
S.E. de Mink, L.A.C. van Son, Y.L.L. Götberg, S. Zellmann, A.V.-G. Alejandro Vigna-Gómez,
M. Renzo, S. Wu, S.L. Schrøder, R.J. Foley, T.H.-S. Tenley Hutchinson-Smith, ArXiv
(n.d.).
date_created: 2023-08-21T10:10:41Z
date_published: 2020-11-12T00:00:00Z
date_updated: 2023-08-22T11:03:00Z
day: '12'
doi: 10.48550/arXiv.2011.06630
external_id:
arxiv:
- '2011.06630'
language:
- iso: eng
main_file_link:
- open_access: '1'
url: https://doi.org/10.48550/arXiv.2011.06630
month: '11'
oa: 1
oa_version: Preprint
publication: arXiv
publication_status: submitted
status: public
title: Successful common envelope ejection and binary neutron star formation in 3D
hydrodynamics
type: preprint
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
year: '2020'
...
---
_id: '8699'
abstract:
- lang: eng
text: In the high spin–orbit-coupled Sr2IrO4, the high sensitivity of the ground
state to the details of the local lattice structure shows a large potential for
the manipulation of the functional properties by inducing local lattice distortions.
We use epitaxial strain to modify the Ir–O bond geometry in Sr2IrO4 and perform
momentum-dependent resonant inelastic X-ray scattering (RIXS) at the metal and
at the ligand sites to unveil the response of the low-energy elementary excitations.
We observe that the pseudospin-wave dispersion for tensile-strained Sr2IrO4 films
displays large softening along the [h,0] direction, while along the [h,h] direction
it shows hardening. This evolution reveals a renormalization of the magnetic interactions
caused by a strain-driven cross-over from anisotropic to isotropic interactions
between the magnetic moments. Moreover, we detect dispersive electron–hole pair
excitations which shift to lower (higher) energies upon compressive (tensile)
strain, manifesting a reduction (increase) in the size of the charge gap. This
behavior shows an intimate coupling between charge excitations and lattice distortions
in Sr2IrO4, originating from the modified hopping elements between the t2g orbitals.
Our work highlights the central role played by the lattice degrees of freedom
in determining both the pseudospin and charge excitations of Sr2IrO4 and provides
valuable information toward the control of the ground state of complex oxides
in the presence of high spin–orbit coupling.
acknowledgement: 'We gratefully acknowledge C. Sahle for experimental support at the
ID20 beamline of the ESRF. The soft X-ray experiments were carried out at the ADRESS
beamline of the Swiss Light Source, Paul Scherrer Institut (PSI). E. Paris and T.S.
thank X. Lu and C. Monney for valuable discussions. The work at PSI is supported
by the Swiss National Science Foundation (SNSF) through Project 200021_178867, the
NCCR (National Centre of Competence in Research) MARVEL (Materials’ Revolution:
Computational Design and Discovery of Novel Materials) and the Sinergia network
Mott Physics Beyond the Heisenberg Model (MPBH) (SNSF Research Grants CRSII2_160765/1
and CRSII2_141962). K.W. acknowledges support by the Narodowe Centrum Nauki Projects
2016/22/E/ST3/00560 and 2016/23/B/ST3/00839. E.M.P. and M.N. acknowledge funding
from the European Union’s Horizon 2020 research and innovation programme under the
Marie Sklodowska-Curie Grant Agreements 754411 and 701647, respectively. M.R. was
supported by the Swiss National Science Foundation under Project 200021 – 182695.
This research used resources of the APS, a U.S. Department of Energy (DOE) Office
of Science User Facility operated for the DOE Office of Science by Argonne National
Laboratory under Contract DE-AC02-06CH11357.'
article_processing_charge: No
article_type: original
author:
- first_name: Eugenio
full_name: Paris, Eugenio
last_name: Paris
- first_name: Yi
full_name: Tseng, Yi
last_name: Tseng
- first_name: Ekaterina
full_name: Paerschke, Ekaterina
id: 8275014E-6063-11E9-9B7F-6338E6697425
last_name: Paerschke
orcid: 0000-0003-0853-8182
- first_name: Wenliang
full_name: Zhang, Wenliang
last_name: Zhang
- first_name: Mary H
full_name: Upton, Mary H
last_name: Upton
- first_name: Anna
full_name: Efimenko, Anna
last_name: Efimenko
- first_name: Katharina
full_name: Rolfs, Katharina
last_name: Rolfs
- first_name: Daniel E
full_name: McNally, Daniel E
last_name: McNally
- first_name: Laura
full_name: Maurel, Laura
last_name: Maurel
- first_name: Muntaser
full_name: Naamneh, Muntaser
last_name: Naamneh
- first_name: Marco
full_name: Caputo, Marco
last_name: Caputo
- first_name: Vladimir N
full_name: Strocov, Vladimir N
last_name: Strocov
- first_name: Zhiming
full_name: Wang, Zhiming
last_name: Wang
- first_name: Diego
full_name: Casa, Diego
last_name: Casa
- first_name: Christof W
full_name: Schneider, Christof W
last_name: Schneider
- first_name: Ekaterina
full_name: Pomjakushina, Ekaterina
last_name: Pomjakushina
- first_name: Krzysztof
full_name: Wohlfeld, Krzysztof
last_name: Wohlfeld
- first_name: Milan
full_name: Radovic, Milan
last_name: Radovic
- first_name: Thorsten
full_name: Schmitt, Thorsten
last_name: Schmitt
citation:
ama: Paris E, Tseng Y, Paerschke E, et al. Strain engineering of the charge and
spin-orbital interactions in Sr2IrO4. Proceedings of the National Academy of
Sciences of the United States of America. 2020;117(40):24764-24770. doi:10.1073/pnas.2012043117
apa: Paris, E., Tseng, Y., Paerschke, E., Zhang, W., Upton, M. H., Efimenko, A.,
… Schmitt, T. (2020). Strain engineering of the charge and spin-orbital interactions
in Sr2IrO4. Proceedings of the National Academy of Sciences of the United States
of America. National Academy of Sciences. https://doi.org/10.1073/pnas.2012043117
chicago: Paris, Eugenio, Yi Tseng, Ekaterina Paerschke, Wenliang Zhang, Mary H Upton,
Anna Efimenko, Katharina Rolfs, et al. “Strain Engineering of the Charge and Spin-Orbital
Interactions in Sr2IrO4.” Proceedings of the National Academy of Sciences of
the United States of America. National Academy of Sciences, 2020. https://doi.org/10.1073/pnas.2012043117.
ieee: E. Paris et al., “Strain engineering of the charge and spin-orbital
interactions in Sr2IrO4,” Proceedings of the National Academy of Sciences of
the United States of America, vol. 117, no. 40. National Academy of Sciences,
pp. 24764–24770, 2020.
ista: Paris E, Tseng Y, Paerschke E, Zhang W, Upton MH, Efimenko A, Rolfs K, McNally
DE, Maurel L, Naamneh M, Caputo M, Strocov VN, Wang Z, Casa D, Schneider CW, Pomjakushina
E, Wohlfeld K, Radovic M, Schmitt T. 2020. Strain engineering of the charge and
spin-orbital interactions in Sr2IrO4. Proceedings of the National Academy of Sciences
of the United States of America. 117(40), 24764–24770.
mla: Paris, Eugenio, et al. “Strain Engineering of the Charge and Spin-Orbital Interactions
in Sr2IrO4.” Proceedings of the National Academy of Sciences of the United
States of America, vol. 117, no. 40, National Academy of Sciences, 2020, pp.
24764–70, doi:10.1073/pnas.2012043117.
short: E. Paris, Y. Tseng, E. Paerschke, W. Zhang, M.H. Upton, A. Efimenko, K. Rolfs,
D.E. McNally, L. Maurel, M. Naamneh, M. Caputo, V.N. Strocov, Z. Wang, D. Casa,
C.W. Schneider, E. Pomjakushina, K. Wohlfeld, M. Radovic, T. Schmitt, Proceedings
of the National Academy of Sciences of the United States of America 117 (2020)
24764–24770.
date_created: 2020-10-25T23:01:17Z
date_published: 2020-10-06T00:00:00Z
date_updated: 2023-08-22T12:11:52Z
day: '06'
ddc:
- '530'
department:
- _id: MiLe
doi: 10.1073/pnas.2012043117
ec_funded: 1
external_id:
arxiv:
- '2009.12262'
isi:
- '000579059100029'
pmid:
- '32958669'
file:
- access_level: open_access
checksum: 1638fa36b442e2868576c6dd7d6dc505
content_type: application/pdf
creator: cziletti
date_created: 2020-10-28T11:53:12Z
date_updated: 2020-10-28T11:53:12Z
file_id: '8715'
file_name: 2020_PNAS_Paris.pdf
file_size: 1176522
relation: main_file
success: 1
file_date_updated: 2020-10-28T11:53:12Z
has_accepted_license: '1'
intvolume: ' 117'
isi: 1
issue: '40'
language:
- iso: eng
month: '10'
oa: 1
oa_version: Published Version
page: 24764-24770
pmid: 1
project:
- _id: 260C2330-B435-11E9-9278-68D0E5697425
call_identifier: H2020
grant_number: '754411'
name: ISTplus - Postdoctoral Fellowships
publication: Proceedings of the National Academy of Sciences of the United States
of America
publication_identifier:
eissn:
- '10916490'
issn:
- '00278424'
publication_status: published
publisher: National Academy of Sciences
quality_controlled: '1'
scopus_import: '1'
status: public
title: Strain engineering of the charge and spin-orbital interactions in Sr2IrO4
tmp:
image: /images/cc_by_nc_nd.png
legal_code_url: https://creativecommons.org/licenses/by-nc-nd/4.0/legalcode
name: Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International
(CC BY-NC-ND 4.0)
short: CC BY-NC-ND (4.0)
type: journal_article
user_id: 4359f0d1-fa6c-11eb-b949-802e58b17ae8
volume: 117
year: '2020'
...
---
_id: '8737'
abstract:
- lang: eng
text: Mitochondrial complex I couples NADH:ubiquinone oxidoreduction to proton pumping
by an unknown mechanism. Here, we present cryo-electron microscopy structures
of ovine complex I in five different conditions, including turnover, at resolutions
up to 2.3 to 2.5 angstroms. Resolved water molecules allowed us to experimentally
define the proton translocation pathways. Quinone binds at three positions along
the quinone cavity, as does the inhibitor rotenone that also binds within subunit
ND4. Dramatic conformational changes around the quinone cavity couple the redox
reaction to proton translocation during open-to-closed state transitions of the
enzyme. In the induced deactive state, the open conformation is arrested by the
ND6 subunit. We propose a detailed molecular coupling mechanism of complex I,
which is an unexpected combination of conformational changes and electrostatic
interactions.
acknowledged_ssus:
- _id: LifeSc
- _id: EM-Fac
acknowledgement: We thank J. Novacek (CEITEC Brno) and V.-V. Hodirnau (IST Austria)
for their help with collecting cryo-EM datasets. We thank the IST Life Science and
Electron Microscopy Facilities for providing equipment. This work has been supported
by iNEXT,project number 653706, funded by the Horizon 2020 program of the European
Union. This article reflects only the authors’view,and the European Commission is
not responsible for any use that may be made of the information it contains. CIISB
research infrastructure project LM2015043 funded by MEYS CR is gratefully acknowledged
for the financial support of the measurements at the CF Cryo-electron Microscopy
and Tomography CEITEC MU.This project has received funding from the European Union’s
Horizon 2020 research and innovation program under the Marie Skłodowska-Curie Grant
Agreement no. 665385
article_number: eabc4209
article_processing_charge: No
article_type: original
author:
- first_name: Domen
full_name: Kampjut, Domen
id: 37233050-F248-11E8-B48F-1D18A9856A87
last_name: Kampjut
- first_name: Leonid A
full_name: Sazanov, Leonid A
id: 338D39FE-F248-11E8-B48F-1D18A9856A87
last_name: Sazanov
orcid: 0000-0002-0977-7989
citation:
ama: Kampjut D, Sazanov LA. The coupling mechanism of mammalian respiratory complex
I. Science. 2020;370(6516). doi:10.1126/science.abc4209
apa: Kampjut, D., & Sazanov, L. A. (2020). The coupling mechanism of mammalian
respiratory complex I. Science. American Association for the Advancement
of Science. https://doi.org/10.1126/science.abc4209
chicago: Kampjut, Domen, and Leonid A Sazanov. “The Coupling Mechanism of Mammalian
Respiratory Complex I.” Science. American Association for the Advancement
of Science, 2020. https://doi.org/10.1126/science.abc4209.
ieee: D. Kampjut and L. A. Sazanov, “The coupling mechanism of mammalian respiratory
complex I,” Science, vol. 370, no. 6516. American Association for the Advancement
of Science, 2020.
ista: Kampjut D, Sazanov LA. 2020. The coupling mechanism of mammalian respiratory
complex I. Science. 370(6516), eabc4209.
mla: Kampjut, Domen, and Leonid A. Sazanov. “The Coupling Mechanism of Mammalian
Respiratory Complex I.” Science, vol. 370, no. 6516, eabc4209, American
Association for the Advancement of Science, 2020, doi:10.1126/science.abc4209.
short: D. Kampjut, L.A. Sazanov, Science 370 (2020).
date_created: 2020-11-08T23:01:23Z
date_published: 2020-10-30T00:00:00Z
date_updated: 2023-08-22T12:35:38Z
day: '30'
ddc:
- '572'
department:
- _id: LeSa
doi: 10.1126/science.abc4209
ec_funded: 1
external_id:
isi:
- '000583031800004'
pmid:
- '32972993'
file:
- access_level: open_access
checksum: 658ba90979ca9528a2efdfac8547047a
content_type: application/pdf
creator: lsazanov
date_created: 2020-11-26T18:47:58Z
date_updated: 2020-11-26T18:47:58Z
file_id: '8820'
file_name: Full_manuscript_with_SI_opt_red.pdf
file_size: 7618987
relation: main_file
success: 1
file_date_updated: 2020-11-26T18:47:58Z
has_accepted_license: '1'
intvolume: ' 370'
isi: 1
issue: '6516'
language:
- iso: eng
month: '10'
oa: 1
oa_version: Submitted Version
pmid: 1
project:
- _id: 2564DBCA-B435-11E9-9278-68D0E5697425
call_identifier: H2020
grant_number: '665385'
name: International IST Doctoral Program
publication: Science
publication_identifier:
eissn:
- '10959203'
publication_status: published
publisher: American Association for the Advancement of Science
quality_controlled: '1'
scopus_import: '1'
status: public
title: The coupling mechanism of mammalian respiratory complex I
type: journal_article
user_id: 4359f0d1-fa6c-11eb-b949-802e58b17ae8
volume: 370
year: '2020'
...
---
_id: '8722'
abstract:
- lang: eng
text: "Load imbalance pervasively exists in distributed deep learning training systems,
either caused by the inherent imbalance in learned tasks or by the system itself.
Traditional synchronous Stochastic Gradient Descent (SGD)\r\nachieves good accuracy
for a wide variety of tasks, but relies on global synchronization to accumulate
the gradients at every training step. In this paper, we propose eager-SGD, which
relaxes the global synchronization for\r\ndecentralized accumulation. To implement
eager-SGD, we propose to use two partial collectives: solo and majority. With
solo allreduce, the faster processes contribute their gradients eagerly without
waiting for the slower processes, whereas with majority allreduce, at least half
of the participants must contribute gradients before continuing, all without using
a central parameter server. We theoretically prove the convergence of the algorithms
and describe the partial collectives in detail. Experimental results on load-imbalanced
environments (CIFAR-10, ImageNet, and UCF101 datasets) show\r\nthat eager-SGD
achieves 1.27x speedup over the state-of-the-art synchronous SGD, without losing
accuracy."
article_processing_charge: No
author:
- first_name: Shigang
full_name: Li, Shigang
last_name: Li
- first_name: Tal Ben-Nun
full_name: Tal Ben-Nun, Tal Ben-Nun
last_name: Tal Ben-Nun
- first_name: Salvatore Di
full_name: Girolamo, Salvatore Di
last_name: Girolamo
- first_name: Dan-Adrian
full_name: Alistarh, Dan-Adrian
id: 4A899BFC-F248-11E8-B48F-1D18A9856A87
last_name: Alistarh
orcid: 0000-0003-3650-940X
- first_name: Torsten
full_name: Hoefler, Torsten
last_name: Hoefler
citation:
ama: 'Li S, Tal Ben-Nun TB-N, Girolamo SD, Alistarh D-A, Hoefler T. Taming unbalanced
training workloads in deep learning with partial collective operations. In: Proceedings
of the 25th ACM SIGPLAN Symposium on Principles and Practice of Parallel Programming.
Association for Computing Machinery; 2020:45-61. doi:10.1145/3332466.3374528'
apa: 'Li, S., Tal Ben-Nun, T. B.-N., Girolamo, S. D., Alistarh, D.-A., & Hoefler,
T. (2020). Taming unbalanced training workloads in deep learning with partial
collective operations. In Proceedings of the 25th ACM SIGPLAN Symposium on
Principles and Practice of Parallel Programming (pp. 45–61). San Diego, CA,
United States: Association for Computing Machinery. https://doi.org/10.1145/3332466.3374528'
chicago: Li, Shigang, Tal Ben-Nun Tal Ben-Nun, Salvatore Di Girolamo, Dan-Adrian
Alistarh, and Torsten Hoefler. “Taming Unbalanced Training Workloads in Deep Learning
with Partial Collective Operations.” In Proceedings of the 25th ACM SIGPLAN
Symposium on Principles and Practice of Parallel Programming, 45–61. Association
for Computing Machinery, 2020. https://doi.org/10.1145/3332466.3374528.
ieee: S. Li, T. B.-N. Tal Ben-Nun, S. D. Girolamo, D.-A. Alistarh, and T. Hoefler,
“Taming unbalanced training workloads in deep learning with partial collective
operations,” in Proceedings of the 25th ACM SIGPLAN Symposium on Principles
and Practice of Parallel Programming, San Diego, CA, United States, 2020,
pp. 45–61.
ista: 'Li S, Tal Ben-Nun TB-N, Girolamo SD, Alistarh D-A, Hoefler T. 2020. Taming
unbalanced training workloads in deep learning with partial collective operations.
Proceedings of the 25th ACM SIGPLAN Symposium on Principles and Practice of Parallel
Programming. PPoPP: Sympopsium on Principles and Practice of Parallel Programming,
45–61.'
mla: Li, Shigang, et al. “Taming Unbalanced Training Workloads in Deep Learning
with Partial Collective Operations.” Proceedings of the 25th ACM SIGPLAN Symposium
on Principles and Practice of Parallel Programming, Association for Computing
Machinery, 2020, pp. 45–61, doi:10.1145/3332466.3374528.
short: S. Li, T.B.-N. Tal Ben-Nun, S.D. Girolamo, D.-A. Alistarh, T. Hoefler, in:,
Proceedings of the 25th ACM SIGPLAN Symposium on Principles and Practice of Parallel
Programming, Association for Computing Machinery, 2020, pp. 45–61.
conference:
end_date: 2020-02-26
location: San Diego, CA, United States
name: 'PPoPP: Sympopsium on Principles and Practice of Parallel Programming'
start_date: 2020-02-22
date_created: 2020-11-05T15:25:30Z
date_published: 2020-02-01T00:00:00Z
date_updated: 2023-08-22T12:13:48Z
day: '01'
department:
- _id: DaAl
doi: 10.1145/3332466.3374528
ec_funded: 1
external_id:
arxiv:
- '1908.04207'
isi:
- '000564476500004'
isi: 1
language:
- iso: eng
main_file_link:
- open_access: '1'
url: https://arxiv.org/abs/1908.04207
month: '02'
oa: 1
oa_version: Preprint
page: 45-61
project:
- _id: 268A44D6-B435-11E9-9278-68D0E5697425
call_identifier: H2020
grant_number: '805223'
name: Elastic Coordination for Scalable Machine Learning
publication: Proceedings of the 25th ACM SIGPLAN Symposium on Principles and Practice
of Parallel Programming
publication_status: published
publisher: Association for Computing Machinery
quality_controlled: '1'
status: public
title: Taming unbalanced training workloads in deep learning with partial collective
operations
type: conference
user_id: 4359f0d1-fa6c-11eb-b949-802e58b17ae8
year: '2020'
...
---
_id: '8744'
abstract:
- lang: eng
text: Understanding the conformational sampling of translation-arrested ribosome
nascent chain complexes is key to understand co-translational folding. Up to now,
coupling of cysteine oxidation, disulfide bond formation and structure formation
in nascent chains has remained elusive. Here, we investigate the eye-lens protein
γB-crystallin in the ribosomal exit tunnel. Using mass spectrometry, theoretical
simulations, dynamic nuclear polarization-enhanced solid-state nuclear magnetic
resonance and cryo-electron microscopy, we show that thiol groups of cysteine
residues undergo S-glutathionylation and S-nitrosylation and form non-native disulfide
bonds. Thus, covalent modification chemistry occurs already prior to nascent chain
release as the ribosome exit tunnel provides sufficient space even for disulfide
bond formation which can guide protein folding.
acknowledgement: 'We acknowledge help from Anja Seybert, Margot Frangakis, Diana Grewe,
Mikhail Eltsov, Utz Ermel, and Shintaro Aibara. The work was supported by Deutsche
Forschungsgemeinschaft in the CLiC graduate school. Work at the Center for Biomolecular
Magnetic Resonance (BMRZ) is supported by the German state of Hesse. The work at
BMRZ has been supported by the state of Hesse. L.S. has been supported by the DFG
graduate college: CLiC.'
article_number: '5569'
article_processing_charge: No
article_type: original
author:
- first_name: Linda
full_name: Schulte, Linda
last_name: Schulte
- first_name: Jiafei
full_name: Mao, Jiafei
last_name: Mao
- first_name: Julian
full_name: Reitz, Julian
last_name: Reitz
- first_name: Sridhar
full_name: Sreeramulu, Sridhar
last_name: Sreeramulu
- first_name: Denis
full_name: Kudlinzki, Denis
last_name: Kudlinzki
- first_name: Victor-Valentin
full_name: Hodirnau, Victor-Valentin
id: 3661B498-F248-11E8-B48F-1D18A9856A87
last_name: Hodirnau
- first_name: Jakob
full_name: Meier-Credo, Jakob
last_name: Meier-Credo
- first_name: Krishna
full_name: Saxena, Krishna
last_name: Saxena
- first_name: Florian
full_name: Buhr, Florian
last_name: Buhr
- first_name: Julian D.
full_name: Langer, Julian D.
last_name: Langer
- first_name: Martin
full_name: Blackledge, Martin
last_name: Blackledge
- first_name: Achilleas S.
full_name: Frangakis, Achilleas S.
last_name: Frangakis
- first_name: Clemens
full_name: Glaubitz, Clemens
last_name: Glaubitz
- first_name: Harald
full_name: Schwalbe, Harald
last_name: Schwalbe
citation:
ama: Schulte L, Mao J, Reitz J, et al. Cysteine oxidation and disulfide formation
in the ribosomal exit tunnel. Nature Communications. 2020;11. doi:10.1038/s41467-020-19372-x
apa: Schulte, L., Mao, J., Reitz, J., Sreeramulu, S., Kudlinzki, D., Hodirnau, V.-V.,
… Schwalbe, H. (2020). Cysteine oxidation and disulfide formation in the ribosomal
exit tunnel. Nature Communications. Springer Nature. https://doi.org/10.1038/s41467-020-19372-x
chicago: Schulte, Linda, Jiafei Mao, Julian Reitz, Sridhar Sreeramulu, Denis Kudlinzki,
Victor-Valentin Hodirnau, Jakob Meier-Credo, et al. “Cysteine Oxidation and Disulfide
Formation in the Ribosomal Exit Tunnel.” Nature Communications. Springer
Nature, 2020. https://doi.org/10.1038/s41467-020-19372-x.
ieee: L. Schulte et al., “Cysteine oxidation and disulfide formation in the
ribosomal exit tunnel,” Nature Communications, vol. 11. Springer Nature,
2020.
ista: Schulte L, Mao J, Reitz J, Sreeramulu S, Kudlinzki D, Hodirnau V-V, Meier-Credo
J, Saxena K, Buhr F, Langer JD, Blackledge M, Frangakis AS, Glaubitz C, Schwalbe
H. 2020. Cysteine oxidation and disulfide formation in the ribosomal exit tunnel.
Nature Communications. 11, 5569.
mla: Schulte, Linda, et al. “Cysteine Oxidation and Disulfide Formation in the Ribosomal
Exit Tunnel.” Nature Communications, vol. 11, 5569, Springer Nature, 2020,
doi:10.1038/s41467-020-19372-x.
short: L. Schulte, J. Mao, J. Reitz, S. Sreeramulu, D. Kudlinzki, V.-V. Hodirnau,
J. Meier-Credo, K. Saxena, F. Buhr, J.D. Langer, M. Blackledge, A.S. Frangakis,
C. Glaubitz, H. Schwalbe, Nature Communications 11 (2020).
date_created: 2020-11-09T07:49:36Z
date_published: 2020-11-04T00:00:00Z
date_updated: 2023-08-22T12:36:07Z
day: '04'
ddc:
- '570'
department:
- _id: EM-Fac
doi: 10.1038/s41467-020-19372-x
external_id:
isi:
- '000592028600001'
file:
- access_level: open_access
checksum: b2688f0347e69e6629bba582077278c5
content_type: application/pdf
creator: dernst
date_created: 2020-11-09T07:56:24Z
date_updated: 2020-11-09T07:56:24Z
file_id: '8745'
file_name: 2020_NatureComm_Schulte.pdf
file_size: 1670898
relation: main_file
success: 1
file_date_updated: 2020-11-09T07:56:24Z
has_accepted_license: '1'
intvolume: ' 11'
isi: 1
keyword:
- General Biochemistry
- Genetics and Molecular Biology
- General Physics and Astronomy
- General Chemistry
language:
- iso: eng
license: https://creativecommons.org/licenses/by/4.0/
month: '11'
oa: 1
oa_version: Published Version
publication: Nature Communications
publication_identifier:
issn:
- 2041-1723
publication_status: published
publisher: Springer Nature
quality_controlled: '1'
scopus_import: '1'
status: public
title: Cysteine oxidation and disulfide formation in the ribosomal exit tunnel
tmp:
image: /images/cc_by.png
legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
short: CC BY (4.0)
type: journal_article
user_id: 4359f0d1-fa6c-11eb-b949-802e58b17ae8
volume: 11
year: '2020'
...
---
_id: '8747'
abstract:
- lang: eng
text: "Appropriately designed nanocomposites allow improving the thermoelectric
performance by several mechanisms, including phonon scattering, modulation doping
and energy filtering, while additionally promoting better mechanical properties
than those of crystalline materials. Here, a strategy for producing Bi2Te3–Cu2xTe
nanocomposites based on the consolidation of heterostructured nanoparticles is
described and the thermoelectric properties of the obtained materials are investigated.
We first detail a two-step solution-based process to produce Bi2Te3–Cu2xTe heteronanostructures,
based on the growth of Cu2xTe nanocrystals on the surface of Bi2Te3 nanowires.
We characterize the structural and chemical properties of the synthesized nanostructures
and of the nanocomposites\r\nproduced by hot-pressing the particles at moderate
temperatures. Besides, the transport properties of the nanocomposites are investigated
as a function of the amount of Cu introduced. Overall, the presence of Cu decreases
the material thermal conductivity through promotion of phonon scattering, modulates
the charge carrier concentration through electron spillover, and increases the
Seebeck coefficient through filtering of charge carriers at energy barriers. These
effects result in an improvement of over 50% of the thermoelectric figure of merit
of Bi2Te3."
acknowledgement: "This work was supported by the European Regional Development Funds
and by the Spanish Ministerio de Economı´a y\r\nCompetitividad through the project
SEHTOP (ENE2016-77798-C4-3-R). Y. Z. and X. H., thank the China Scholarship Council
for scholarship support. M. C. has received funding from the European Union’s Horizon
2020 Research and Innovation programme under the Marie Skłodowska-Curie Grant Agreement
No. 665385. M. I. acknowledges financial support from IST Austria. Y. L. acknowledges
funding from the European Union’s Horizon 2020 Research and Innovation Programme
under the Marie Sklodowska-Curie grant agreement no. 754411. ICN2 acknowledges funding
from Generalitat de Catalunya 2017 SGR 327 and the Spanish MINECO project ENE2017-85087-C3.
ICN2 is supported by the Severo Ochoa program from the Spanish MINECO (grant no.
SEV-2017-0706) and is funded by the CERCA Programme/Generalitat de Catalunya. Part
of the present work has been performed in the framework of Universitat \r\nAuto`noma
de Barcelona Materials Science PhD program."
article_processing_charge: No
article_type: original
author:
- first_name: Yu
full_name: Zhang, Yu
last_name: Zhang
- first_name: Yu
full_name: Liu, Yu
id: 2A70014E-F248-11E8-B48F-1D18A9856A87
last_name: Liu
orcid: 0000-0001-7313-6740
- first_name: Mariano
full_name: Calcabrini, Mariano
last_name: Calcabrini
- first_name: Congcong
full_name: Xing, Congcong
last_name: Xing
- first_name: Xu
full_name: Han, Xu
last_name: Han
- first_name: Jordi
full_name: Arbiol, Jordi
last_name: Arbiol
- first_name: Doris
full_name: Cadavid, Doris
last_name: Cadavid
- first_name: Maria
full_name: Ibáñez, Maria
id: 43C61214-F248-11E8-B48F-1D18A9856A87
last_name: Ibáñez
orcid: 0000-0001-5013-2843
- first_name: Andreu
full_name: Cabot, Andreu
last_name: Cabot
citation:
ama: Zhang Y, Liu Y, Calcabrini M, et al. Bismuth telluride-copper telluride nanocomposites
from heterostructured building blocks. Journal of Materials Chemistry C.
2020;8(40):14092-14099. doi:10.1039/D0TC02182B
apa: Zhang, Y., Liu, Y., Calcabrini, M., Xing, C., Han, X., Arbiol, J., … Cabot,
A. (2020). Bismuth telluride-copper telluride nanocomposites from heterostructured
building blocks. Journal of Materials Chemistry C. Royal Society of Chemistry.
https://doi.org/10.1039/D0TC02182B
chicago: Zhang, Yu, Yu Liu, Mariano Calcabrini, Congcong Xing, Xu Han, Jordi Arbiol,
Doris Cadavid, Maria Ibáñez, and Andreu Cabot. “Bismuth Telluride-Copper Telluride
Nanocomposites from Heterostructured Building Blocks.” Journal of Materials
Chemistry C. Royal Society of Chemistry, 2020. https://doi.org/10.1039/D0TC02182B.
ieee: Y. Zhang et al., “Bismuth telluride-copper telluride nanocomposites
from heterostructured building blocks,” Journal of Materials Chemistry C,
vol. 8, no. 40. Royal Society of Chemistry, pp. 14092–14099, 2020.
ista: Zhang Y, Liu Y, Calcabrini M, Xing C, Han X, Arbiol J, Cadavid D, Ibáñez M,
Cabot A. 2020. Bismuth telluride-copper telluride nanocomposites from heterostructured
building blocks. Journal of Materials Chemistry C. 8(40), 14092–14099.
mla: Zhang, Yu, et al. “Bismuth Telluride-Copper Telluride Nanocomposites from Heterostructured
Building Blocks.” Journal of Materials Chemistry C, vol. 8, no. 40, Royal
Society of Chemistry, 2020, pp. 14092–99, doi:10.1039/D0TC02182B.
short: Y. Zhang, Y. Liu, M. Calcabrini, C. Xing, X. Han, J. Arbiol, D. Cadavid,
M. Ibáñez, A. Cabot, Journal of Materials Chemistry C 8 (2020) 14092–14099.
date_created: 2020-11-09T08:37:51Z
date_published: 2020-10-28T00:00:00Z
date_updated: 2023-08-22T12:41:05Z
day: '28'
department:
- _id: MaIb
doi: 10.1039/D0TC02182B
ec_funded: 1
external_id:
isi:
- '000581559100015'
intvolume: ' 8'
isi: 1
issue: '40'
language:
- iso: eng
month: '10'
oa_version: None
page: 14092-14099
project:
- _id: 260C2330-B435-11E9-9278-68D0E5697425
call_identifier: H2020
grant_number: '754411'
name: ISTplus - Postdoctoral Fellowships
publication: Journal of Materials Chemistry C
publication_status: published
publisher: Royal Society of Chemistry
quality_controlled: '1'
scopus_import: '1'
status: public
title: Bismuth telluride-copper telluride nanocomposites from heterostructured building
blocks
type: journal_article
user_id: 4359f0d1-fa6c-11eb-b949-802e58b17ae8
volume: 8
year: '2020'
...
---
_id: '14095'
abstract:
- lang: eng
text: 'The Habitable Exoplanet Observatory, or HabEx, has been designed to be the
Great Observatory of the 2030s. For the first time in human history, technologies
have matured sufficiently to enable an affordable space-based telescope mission
capable of discovering and characterizing Earthlike planets orbiting nearby bright
sunlike stars in order to search for signs of habitability and biosignatures.
Such a mission can also be equipped with instrumentation that will enable broad
and exciting general astrophysics and planetary science not possible from current
or planned facilities. HabEx is a space telescope with unique imaging and multi-object
spectroscopic capabilities at wavelengths ranging from ultraviolet (UV) to near-IR.
These capabilities allow for a broad suite of compelling science that cuts across
the entire NASA astrophysics portfolio. HabEx has three primary science goals:
(1) Seek out nearby worlds and explore their habitability; (2) Map out nearby
planetary systems and understand the diversity of the worlds they contain; (3)
Enable new explorations of astrophysical systems from our own solar system to
external galaxies by extending our reach in the UV through near-IR. This Great
Observatory science will be selected through a competed GO program, and will account
for about 50% of the HabEx primary mission. The preferred HabEx architecture is
a 4m, monolithic, off-axis telescope that is diffraction-limited at 0.4 microns
and is in an L2 orbit. HabEx employs two starlight suppression systems: a coronagraph
and a starshade, each with their own dedicated instrument.'
article_number: '2001.06683'
article_processing_charge: No
author:
- first_name: B. Scott
full_name: Gaudi, B. Scott
last_name: Gaudi
- first_name: Sara
full_name: Seager, Sara
last_name: Seager
- first_name: Bertrand
full_name: Mennesson, Bertrand
last_name: Mennesson
- first_name: Alina
full_name: Kiessling, Alina
last_name: Kiessling
- first_name: Keith
full_name: Warfield, Keith
last_name: Warfield
- first_name: Kerri
full_name: Cahoy, Kerri
last_name: Cahoy
- first_name: John T.
full_name: Clarke, John T.
last_name: Clarke
- first_name: Shawn Domagal-Goldman
full_name: Shawn Domagal-Goldman, Shawn Domagal-Goldman
last_name: Shawn Domagal-Goldman
- first_name: Lee
full_name: Feinberg, Lee
last_name: Feinberg
- first_name: Olivier
full_name: Guyon, Olivier
last_name: Guyon
- first_name: Jeremy
full_name: Kasdin, Jeremy
last_name: Kasdin
- first_name: Dimitri
full_name: Mawet, Dimitri
last_name: Mawet
- first_name: Peter
full_name: Plavchan, Peter
last_name: Plavchan
- first_name: Tyler
full_name: Robinson, Tyler
last_name: Robinson
- first_name: Leslie
full_name: Rogers, Leslie
last_name: Rogers
- first_name: Paul
full_name: Scowen, Paul
last_name: Scowen
- first_name: Rachel
full_name: Somerville, Rachel
last_name: Somerville
- first_name: Karl
full_name: Stapelfeldt, Karl
last_name: Stapelfeldt
- first_name: Christopher
full_name: Stark, Christopher
last_name: Stark
- first_name: Daniel
full_name: Stern, Daniel
last_name: Stern
- first_name: Margaret
full_name: Turnbull, Margaret
last_name: Turnbull
- first_name: Rashied
full_name: Amini, Rashied
last_name: Amini
- first_name: Gary
full_name: Kuan, Gary
last_name: Kuan
- first_name: Stefan
full_name: Martin, Stefan
last_name: Martin
- first_name: Rhonda
full_name: Morgan, Rhonda
last_name: Morgan
- first_name: David
full_name: Redding, David
last_name: Redding
- first_name: H. Philip
full_name: Stahl, H. Philip
last_name: Stahl
- first_name: Ryan
full_name: Webb, Ryan
last_name: Webb
- first_name: Oscar Alvarez-Salazar
full_name: Oscar Alvarez-Salazar, Oscar Alvarez-Salazar
last_name: Oscar Alvarez-Salazar
- first_name: William L.
full_name: Arnold, William L.
last_name: Arnold
- first_name: Manan
full_name: Arya, Manan
last_name: Arya
- first_name: Bala
full_name: Balasubramanian, Bala
last_name: Balasubramanian
- first_name: Mike
full_name: Baysinger, Mike
last_name: Baysinger
- first_name: Ray
full_name: Bell, Ray
last_name: Bell
- first_name: Chris
full_name: Below, Chris
last_name: Below
- first_name: Jonathan
full_name: Benson, Jonathan
last_name: Benson
- first_name: Lindsey
full_name: Blais, Lindsey
last_name: Blais
- first_name: Jeff
full_name: Booth, Jeff
last_name: Booth
- first_name: Robert
full_name: Bourgeois, Robert
last_name: Bourgeois
- first_name: Case
full_name: Bradford, Case
last_name: Bradford
- first_name: Alden
full_name: Brewer, Alden
last_name: Brewer
- first_name: Thomas
full_name: Brooks, Thomas
last_name: Brooks
- first_name: Eric
full_name: Cady, Eric
last_name: Cady
- first_name: Mary
full_name: Caldwell, Mary
last_name: Caldwell
- first_name: Rob
full_name: Calvet, Rob
last_name: Calvet
- first_name: Steven
full_name: Carr, Steven
last_name: Carr
- first_name: Derek
full_name: Chan, Derek
last_name: Chan
- first_name: Velibor
full_name: Cormarkovic, Velibor
last_name: Cormarkovic
- first_name: Keith
full_name: Coste, Keith
last_name: Coste
- first_name: Charlie
full_name: Cox, Charlie
last_name: Cox
- first_name: Rolf
full_name: Danner, Rolf
last_name: Danner
- first_name: Jacqueline
full_name: Davis, Jacqueline
last_name: Davis
- first_name: Larry
full_name: Dewell, Larry
last_name: Dewell
- first_name: Lisa
full_name: Dorsett, Lisa
last_name: Dorsett
- first_name: Daniel
full_name: Dunn, Daniel
last_name: Dunn
- first_name: Matthew
full_name: East, Matthew
last_name: East
- first_name: Michael
full_name: Effinger, Michael
last_name: Effinger
- first_name: Ron
full_name: Eng, Ron
last_name: Eng
- first_name: Greg
full_name: Freebury, Greg
last_name: Freebury
- first_name: Jay
full_name: Garcia, Jay
last_name: Garcia
- first_name: Jonathan
full_name: Gaskin, Jonathan
last_name: Gaskin
- first_name: Suzan
full_name: Greene, Suzan
last_name: Greene
- first_name: John
full_name: Hennessy, John
last_name: Hennessy
- first_name: Evan
full_name: Hilgemann, Evan
last_name: Hilgemann
- first_name: Brad
full_name: Hood, Brad
last_name: Hood
- first_name: Wolfgang
full_name: Holota, Wolfgang
last_name: Holota
- first_name: Scott
full_name: Howe, Scott
last_name: Howe
- first_name: Pei
full_name: Huang, Pei
last_name: Huang
- first_name: Tony
full_name: Hull, Tony
last_name: Hull
- first_name: Ron
full_name: Hunt, Ron
last_name: Hunt
- first_name: Kevin
full_name: Hurd, Kevin
last_name: Hurd
- first_name: Sandra
full_name: Johnson, Sandra
last_name: Johnson
- first_name: Andrew
full_name: Kissil, Andrew
last_name: Kissil
- first_name: Brent
full_name: Knight, Brent
last_name: Knight
- first_name: Daniel
full_name: Kolenz, Daniel
last_name: Kolenz
- first_name: Oliver
full_name: Kraus, Oliver
last_name: Kraus
- first_name: John
full_name: Krist, John
last_name: Krist
- first_name: Mary
full_name: Li, Mary
last_name: Li
- first_name: Doug
full_name: Lisman, Doug
last_name: Lisman
- first_name: Milan
full_name: Mandic, Milan
last_name: Mandic
- first_name: John
full_name: Mann, John
last_name: Mann
- first_name: Luis
full_name: Marchen, Luis
last_name: Marchen
- first_name: Colleen Marrese-Reading
full_name: Colleen Marrese-Reading, Colleen Marrese-Reading
last_name: Colleen Marrese-Reading
- first_name: Jonathan
full_name: McCready, Jonathan
last_name: McCready
- first_name: Jim
full_name: McGown, Jim
last_name: McGown
- first_name: Jessica
full_name: Missun, Jessica
last_name: Missun
- first_name: Andrew
full_name: Miyaguchi, Andrew
last_name: Miyaguchi
- first_name: Bradley
full_name: Moore, Bradley
last_name: Moore
- first_name: Bijan
full_name: Nemati, Bijan
last_name: Nemati
- first_name: Shouleh
full_name: Nikzad, Shouleh
last_name: Nikzad
- first_name: Joel
full_name: Nissen, Joel
last_name: Nissen
- first_name: Megan
full_name: Novicki, Megan
last_name: Novicki
- first_name: Todd
full_name: Perrine, Todd
last_name: Perrine
- first_name: Claudia
full_name: Pineda, Claudia
last_name: Pineda
- first_name: Otto
full_name: Polanco, Otto
last_name: Polanco
- first_name: Dustin
full_name: Putnam, Dustin
last_name: Putnam
- first_name: Atif
full_name: Qureshi, Atif
last_name: Qureshi
- first_name: Michael
full_name: Richards, Michael
last_name: Richards
- first_name: A. J. Eldorado
full_name: Riggs, A. J. Eldorado
last_name: Riggs
- first_name: Michael
full_name: Rodgers, Michael
last_name: Rodgers
- first_name: Mike
full_name: Rud, Mike
last_name: Rud
- first_name: Navtej
full_name: Saini, Navtej
last_name: Saini
- first_name: Dan
full_name: Scalisi, Dan
last_name: Scalisi
- first_name: Dan
full_name: Scharf, Dan
last_name: Scharf
- first_name: Kevin
full_name: Schulz, Kevin
last_name: Schulz
- first_name: Gene
full_name: Serabyn, Gene
last_name: Serabyn
- first_name: Norbert
full_name: Sigrist, Norbert
last_name: Sigrist
- first_name: Glory
full_name: Sikkia, Glory
last_name: Sikkia
- first_name: Andrew
full_name: Singleton, Andrew
last_name: Singleton
- first_name: Stuart
full_name: Shaklan, Stuart
last_name: Shaklan
- first_name: Scott
full_name: Smith, Scott
last_name: Smith
- first_name: Bart
full_name: Southerd, Bart
last_name: Southerd
- first_name: Mark
full_name: Stahl, Mark
last_name: Stahl
- first_name: John
full_name: Steeves, John
last_name: Steeves
- first_name: Brian
full_name: Sturges, Brian
last_name: Sturges
- first_name: Chris
full_name: Sullivan, Chris
last_name: Sullivan
- first_name: Hao
full_name: Tang, Hao
last_name: Tang
- first_name: Neil
full_name: Taras, Neil
last_name: Taras
- first_name: Jonathan
full_name: Tesch, Jonathan
last_name: Tesch
- first_name: Melissa
full_name: Therrell, Melissa
last_name: Therrell
- first_name: Howard
full_name: Tseng, Howard
last_name: Tseng
- first_name: Marty
full_name: Valente, Marty
last_name: Valente
- first_name: David Van
full_name: Buren, David Van
last_name: Buren
- first_name: Juan
full_name: Villalvazo, Juan
last_name: Villalvazo
- first_name: Steve
full_name: Warwick, Steve
last_name: Warwick
- first_name: David
full_name: Webb, David
last_name: Webb
- first_name: Thomas
full_name: Westerhoff, Thomas
last_name: Westerhoff
- first_name: Rush
full_name: Wofford, Rush
last_name: Wofford
- first_name: Gordon
full_name: Wu, Gordon
last_name: Wu
- first_name: Jahning
full_name: Woo, Jahning
last_name: Woo
- first_name: Milana
full_name: Wood, Milana
last_name: Wood
- first_name: John
full_name: Ziemer, John
last_name: Ziemer
- first_name: Giada
full_name: Arney, Giada
last_name: Arney
- first_name: Jay
full_name: Anderson, Jay
last_name: Anderson
- first_name: Jesús Maíz-Apellániz
full_name: Jesús Maíz-Apellániz, Jesús Maíz-Apellániz
last_name: Jesús Maíz-Apellániz
- first_name: James
full_name: Bartlett, James
last_name: Bartlett
- first_name: Ruslan
full_name: Belikov, Ruslan
last_name: Belikov
- first_name: Eduardo
full_name: Bendek, Eduardo
last_name: Bendek
- first_name: Brad
full_name: Cenko, Brad
last_name: Cenko
- first_name: Ewan
full_name: Douglas, Ewan
last_name: Douglas
- first_name: Shannon
full_name: Dulz, Shannon
last_name: Dulz
- first_name: Chris
full_name: Evans, Chris
last_name: Evans
- first_name: Virginie
full_name: Faramaz, Virginie
last_name: Faramaz
- first_name: Y. Katherina
full_name: Feng, Y. Katherina
last_name: Feng
- first_name: Harry
full_name: Ferguson, Harry
last_name: Ferguson
- first_name: Kate
full_name: Follette, Kate
last_name: Follette
- first_name: Saavik
full_name: Ford, Saavik
last_name: Ford
- first_name: Miriam
full_name: García, Miriam
last_name: García
- first_name: Marla
full_name: Geha, Marla
last_name: Geha
- first_name: Dawn
full_name: Gelino, Dawn
last_name: Gelino
- first_name: Ylva Louise Linsdotter
full_name: Götberg, Ylva Louise Linsdotter
id: d0648d0c-0f64-11ee-a2e0-dd0faa2e4f7d
last_name: Götberg
orcid: 0000-0002-6960-6911
- first_name: Sergi
full_name: Hildebrandt, Sergi
last_name: Hildebrandt
- first_name: Renyu
full_name: Hu, Renyu
last_name: Hu
- first_name: Knud
full_name: Jahnke, Knud
last_name: Jahnke
- first_name: Grant
full_name: Kennedy, Grant
last_name: Kennedy
- first_name: Laura
full_name: Kreidberg, Laura
last_name: Kreidberg
- first_name: Andrea
full_name: Isella, Andrea
last_name: Isella
- first_name: Eric
full_name: Lopez, Eric
last_name: Lopez
- first_name: Franck
full_name: Marchis, Franck
last_name: Marchis
- first_name: Lucas
full_name: Macri, Lucas
last_name: Macri
- first_name: Mark
full_name: Marley, Mark
last_name: Marley
- first_name: William
full_name: Matzko, William
last_name: Matzko
- first_name: Johan
full_name: Mazoyer, Johan
last_name: Mazoyer
- first_name: Stephan
full_name: McCandliss, Stephan
last_name: McCandliss
- first_name: Tiffany
full_name: Meshkat, Tiffany
last_name: Meshkat
- first_name: Christoph
full_name: Mordasini, Christoph
last_name: Mordasini
- first_name: Patrick
full_name: Morris, Patrick
last_name: Morris
- first_name: Eric
full_name: Nielsen, Eric
last_name: Nielsen
- first_name: Patrick
full_name: Newman, Patrick
last_name: Newman
- first_name: Erik
full_name: Petigura, Erik
last_name: Petigura
- first_name: Marc
full_name: Postman, Marc
last_name: Postman
- first_name: Amy
full_name: Reines, Amy
last_name: Reines
- first_name: Aki
full_name: Roberge, Aki
last_name: Roberge
- first_name: Ian
full_name: Roederer, Ian
last_name: Roederer
- first_name: Garreth
full_name: Ruane, Garreth
last_name: Ruane
- first_name: Edouard
full_name: Schwieterman, Edouard
last_name: Schwieterman
- first_name: Dan
full_name: Sirbu, Dan
last_name: Sirbu
- first_name: Christopher
full_name: Spalding, Christopher
last_name: Spalding
- first_name: Harry
full_name: Teplitz, Harry
last_name: Teplitz
- first_name: Jason
full_name: Tumlinson, Jason
last_name: Tumlinson
- first_name: Neal
full_name: Turner, Neal
last_name: Turner
- first_name: Jessica
full_name: Werk, Jessica
last_name: Werk
- first_name: Aida
full_name: Wofford, Aida
last_name: Wofford
- first_name: Mark
full_name: Wyatt, Mark
last_name: Wyatt
- first_name: Amber
full_name: Young, Amber
last_name: Young
- first_name: Rob
full_name: Zellem, Rob
last_name: Zellem
citation:
ama: Gaudi BS, Seager S, Mennesson B, et al. The habitable exoplanet observatory
(HabEx) mission concept study final report. arXiv. doi:10.48550/arXiv.2001.06683
apa: Gaudi, B. S., Seager, S., Mennesson, B., Kiessling, A., Warfield, K., Cahoy,
K., … Zellem, R. (n.d.). The habitable exoplanet observatory (HabEx) mission concept
study final report. arXiv. https://doi.org/10.48550/arXiv.2001.06683
chicago: Gaudi, B. Scott, Sara Seager, Bertrand Mennesson, Alina Kiessling, Keith
Warfield, Kerri Cahoy, John T. Clarke, et al. “The Habitable Exoplanet Observatory
(HabEx) Mission Concept Study Final Report.” ArXiv, n.d. https://doi.org/10.48550/arXiv.2001.06683.
ieee: B. S. Gaudi et al., “The habitable exoplanet observatory (HabEx) mission
concept study final report,” arXiv. .
ista: Gaudi BS et al. The habitable exoplanet observatory (HabEx) mission concept
study final report. arXiv, 2001.06683.
mla: Gaudi, B. Scott, et al. “The Habitable Exoplanet Observatory (HabEx) Mission
Concept Study Final Report.” ArXiv, 2001.06683, doi:10.48550/arXiv.2001.06683.
short: B.S. Gaudi, S. Seager, B. Mennesson, A. Kiessling, K. Warfield, K. Cahoy,
J.T. Clarke, S.D.-G. Shawn Domagal-Goldman, L. Feinberg, O. Guyon, J. Kasdin,
D. Mawet, P. Plavchan, T. Robinson, L. Rogers, P. Scowen, R. Somerville, K. Stapelfeldt,
C. Stark, D. Stern, M. Turnbull, R. Amini, G. Kuan, S. Martin, R. Morgan, D. Redding,
H.P. Stahl, R. Webb, O.A.-S. Oscar Alvarez-Salazar, W.L. Arnold, M. Arya, B. Balasubramanian,
M. Baysinger, R. Bell, C. Below, J. Benson, L. Blais, J. Booth, R. Bourgeois,
C. Bradford, A. Brewer, T. Brooks, E. Cady, M. Caldwell, R. Calvet, S. Carr, D.
Chan, V. Cormarkovic, K. Coste, C. Cox, R. Danner, J. Davis, L. Dewell, L. Dorsett,
D. Dunn, M. East, M. Effinger, R. Eng, G. Freebury, J. Garcia, J. Gaskin, S. Greene,
J. Hennessy, E. Hilgemann, B. Hood, W. Holota, S. Howe, P. Huang, T. Hull, R.
Hunt, K. Hurd, S. Johnson, A. Kissil, B. Knight, D. Kolenz, O. Kraus, J. Krist,
M. Li, D. Lisman, M. Mandic, J. Mann, L. Marchen, C.M.-R. Colleen Marrese-Reading,
J. McCready, J. McGown, J. Missun, A. Miyaguchi, B. Moore, B. Nemati, S. Nikzad,
J. Nissen, M. Novicki, T. Perrine, C. Pineda, O. Polanco, D. Putnam, A. Qureshi,
M. Richards, A.J.E. Riggs, M. Rodgers, M. Rud, N. Saini, D. Scalisi, D. Scharf,
K. Schulz, G. Serabyn, N. Sigrist, G. Sikkia, A. Singleton, S. Shaklan, S. Smith,
B. Southerd, M. Stahl, J. Steeves, B. Sturges, C. Sullivan, H. Tang, N. Taras,
J. Tesch, M. Therrell, H. Tseng, M. Valente, D.V. Buren, J. Villalvazo, S. Warwick,
D. Webb, T. Westerhoff, R. Wofford, G. Wu, J. Woo, M. Wood, J. Ziemer, G. Arney,
J. Anderson, J.M.-A. Jesús Maíz-Apellániz, J. Bartlett, R. Belikov, E. Bendek,
B. Cenko, E. Douglas, S. Dulz, C. Evans, V. Faramaz, Y.K. Feng, H. Ferguson, K.
Follette, S. Ford, M. García, M. Geha, D. Gelino, Y.L.L. Götberg, S. Hildebrandt,
R. Hu, K. Jahnke, G. Kennedy, L. Kreidberg, A. Isella, E. Lopez, F. Marchis, L.
Macri, M. Marley, W. Matzko, J. Mazoyer, S. McCandliss, T. Meshkat, C. Mordasini,
P. Morris, E. Nielsen, P. Newman, E. Petigura, M. Postman, A. Reines, A. Roberge,
I. Roederer, G. Ruane, E. Schwieterman, D. Sirbu, C. Spalding, H. Teplitz, J.
Tumlinson, N. Turner, J. Werk, A. Wofford, M. Wyatt, A. Young, R. Zellem, ArXiv
(n.d.).
date_created: 2023-08-21T10:10:21Z
date_published: 2020-01-18T00:00:00Z
date_updated: 2023-08-22T13:13:18Z
day: '18'
doi: 10.48550/arXiv.2001.06683
extern: '1'
external_id:
arxiv:
- '2001.06683'
language:
- iso: eng
main_file_link:
- open_access: '1'
url: ' https://doi.org/10.48550/arXiv.2001.06683'
month: '01'
oa: 1
oa_version: Preprint
publication: arXiv
publication_status: submitted
status: public
title: The habitable exoplanet observatory (HabEx) mission concept study final report
type: preprint
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
year: '2020'
...
---
_id: '8767'
abstract:
- lang: eng
text: Resources are rarely distributed uniformly within a population. Heterogeneity
in the concentration of a drug, the quality of breeding sites, or wealth can all
affect evolutionary dynamics. In this study, we represent a collection of properties
affecting the fitness at a given location using a color. A green node is rich
in resources while a red node is poorer. More colors can represent a broader spectrum
of resource qualities. For a population evolving according to the birth-death
Moran model, the first question we address is which structures, identified by
graph connectivity and graph coloring, are evolutionarily equivalent. We prove
that all properly two-colored, undirected, regular graphs are evolutionarily equivalent
(where “properly colored” means that no two neighbors have the same color). We
then compare the effects of background heterogeneity on properly two-colored graphs
to those with alternative schemes in which the colors are permuted. Finally, we
discuss dynamic coloring as a model for spatiotemporal resource fluctuations,
and we illustrate that random dynamic colorings often diminish the effects of
background heterogeneity relative to a proper two-coloring.
acknowledgement: 'We thank Igor Erovenko for many helpful comments on an earlier version
of this paper. : Army Research Laboratory (grant W911NF-18-2-0265) (M.A.N.); the
Bill & Melinda Gates Foundation (grant OPP1148627) (M.A.N.); the NVIDIA Corporation
(A.M.). The funders had no role in study design, data collection and analysis, decision
to publish, or preparation of the manuscript.'
article_number: e1008402
article_processing_charge: No
article_type: original
author:
- first_name: Kamran
full_name: Kaveh, Kamran
last_name: Kaveh
- first_name: Alex
full_name: McAvoy, Alex
last_name: McAvoy
- first_name: Krishnendu
full_name: Chatterjee, Krishnendu
id: 2E5DCA20-F248-11E8-B48F-1D18A9856A87
last_name: Chatterjee
orcid: 0000-0002-4561-241X
- first_name: Martin A.
full_name: Nowak, Martin A.
last_name: Nowak
citation:
ama: Kaveh K, McAvoy A, Chatterjee K, Nowak MA. The Moran process on 2-chromatic
graphs. PLOS Computational Biology. 2020;16(11). doi:10.1371/journal.pcbi.1008402
apa: Kaveh, K., McAvoy, A., Chatterjee, K., & Nowak, M. A. (2020). The Moran
process on 2-chromatic graphs. PLOS Computational Biology. Public Library
of Science. https://doi.org/10.1371/journal.pcbi.1008402
chicago: Kaveh, Kamran, Alex McAvoy, Krishnendu Chatterjee, and Martin A. Nowak.
“The Moran Process on 2-Chromatic Graphs.” PLOS Computational Biology.
Public Library of Science, 2020. https://doi.org/10.1371/journal.pcbi.1008402.
ieee: K. Kaveh, A. McAvoy, K. Chatterjee, and M. A. Nowak, “The Moran process on
2-chromatic graphs,” PLOS Computational Biology, vol. 16, no. 11. Public
Library of Science, 2020.
ista: Kaveh K, McAvoy A, Chatterjee K, Nowak MA. 2020. The Moran process on 2-chromatic
graphs. PLOS Computational Biology. 16(11), e1008402.
mla: Kaveh, Kamran, et al. “The Moran Process on 2-Chromatic Graphs.” PLOS Computational
Biology, vol. 16, no. 11, e1008402, Public Library of Science, 2020, doi:10.1371/journal.pcbi.1008402.
short: K. Kaveh, A. McAvoy, K. Chatterjee, M.A. Nowak, PLOS Computational Biology
16 (2020).
date_created: 2020-11-18T07:20:23Z
date_published: 2020-11-05T00:00:00Z
date_updated: 2023-08-22T12:49:18Z
day: '05'
ddc:
- '000'
department:
- _id: KrCh
doi: 10.1371/journal.pcbi.1008402
external_id:
isi:
- '000591317200004'
file:
- access_level: open_access
checksum: 555456dd0e47bcf9e0994bcb95577e88
content_type: application/pdf
creator: dernst
date_created: 2020-11-18T07:26:10Z
date_updated: 2020-11-18T07:26:10Z
file_id: '8768'
file_name: 2020_PlosCompBio_Kaveh.pdf
file_size: 2498594
relation: main_file
success: 1
file_date_updated: 2020-11-18T07:26:10Z
has_accepted_license: '1'
intvolume: ' 16'
isi: 1
issue: '11'
keyword:
- Ecology
- Modelling and Simulation
- Computational Theory and Mathematics
- Genetics
- Ecology
- Evolution
- Behavior and Systematics
- Molecular Biology
- Cellular and Molecular Neuroscience
language:
- iso: eng
month: '11'
oa: 1
oa_version: Published Version
publication: PLOS Computational Biology
publication_identifier:
eissn:
- 1553-7358
issn:
- 1553-734X
publication_status: published
publisher: Public Library of Science
quality_controlled: '1'
scopus_import: '1'
status: public
title: The Moran process on 2-chromatic graphs
tmp:
image: /images/cc_by.png
legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
short: CC BY (4.0)
type: journal_article
user_id: 4359f0d1-fa6c-11eb-b949-802e58b17ae8
volume: 16
year: '2020'
...
---
_id: '8750'
abstract:
- lang: eng
text: "Efficiently handling time-triggered and possibly nondeterministic switches\r\nfor
hybrid systems reachability is a challenging task. In this paper we present\r\nan
approach based on conservative set-based enclosure of the dynamics that can\r\nhandle
systems with uncertain parameters and inputs, where the uncertainties\r\nare bound
to given intervals. The method is evaluated on the plant model of an\r\nexperimental
electro-mechanical braking system with periodic controller. In\r\nthis model,
the fast-switching controller dynamics requires simulation time\r\nscales of the
order of nanoseconds. Accurate set-based computations for\r\nrelatively large
time horizons are known to be expensive. However, by\r\nappropriately decoupling
the time variable with respect to the spatial\r\nvariables, and enclosing the
uncertain parameters using interval matrix maps\r\nacting on zonotopes, we show
that the computation time can be lowered to 5000\r\ntimes faster with respect
to previous works. This is a step forward in formal\r\nverification of hybrid
systems because reduced run-times allow engineers to\r\nintroduce more expressiveness
in their models with a relatively inexpensive\r\ncomputational cost."
article_number: '9314994'
article_processing_charge: No
author:
- first_name: Marcelo
full_name: Forets, Marcelo
last_name: Forets
- first_name: Daniel
full_name: Freire, Daniel
last_name: Freire
- first_name: Christian
full_name: Schilling, Christian
id: 3A2F4DCE-F248-11E8-B48F-1D18A9856A87
last_name: Schilling
orcid: 0000-0003-3658-1065
citation:
ama: 'Forets M, Freire D, Schilling C. Efficient reachability analysis of parametric
linear hybrid systems with time-triggered transitions. In: 18th ACM-IEEE International
Conference on Formal Methods and Models for System Design. IEEE; 2020. doi:10.1109/MEMOCODE51338.2020.9314994'
apa: 'Forets, M., Freire, D., & Schilling, C. (2020). Efficient reachability
analysis of parametric linear hybrid systems with time-triggered transitions.
In 18th ACM-IEEE International Conference on Formal Methods and Models for
System Design. Virtual Conference: IEEE. https://doi.org/10.1109/MEMOCODE51338.2020.9314994'
chicago: Forets, Marcelo, Daniel Freire, and Christian Schilling. “Efficient Reachability
Analysis of Parametric Linear Hybrid Systems with Time-Triggered Transitions.”
In 18th ACM-IEEE International Conference on Formal Methods and Models for
System Design. IEEE, 2020. https://doi.org/10.1109/MEMOCODE51338.2020.9314994.
ieee: M. Forets, D. Freire, and C. Schilling, “Efficient reachability analysis of
parametric linear hybrid systems with time-triggered transitions,” in 18th
ACM-IEEE International Conference on Formal Methods and Models for System Design,
Virtual Conference, 2020.
ista: 'Forets M, Freire D, Schilling C. 2020. Efficient reachability analysis of
parametric linear hybrid systems with time-triggered transitions. 18th ACM-IEEE
International Conference on Formal Methods and Models for System Design. MEMOCODE:
Conference on Formal Methods and Models for System Design, 9314994.'
mla: Forets, Marcelo, et al. “Efficient Reachability Analysis of Parametric Linear
Hybrid Systems with Time-Triggered Transitions.” 18th ACM-IEEE International
Conference on Formal Methods and Models for System Design, 9314994, IEEE,
2020, doi:10.1109/MEMOCODE51338.2020.9314994.
short: M. Forets, D. Freire, C. Schilling, in:, 18th ACM-IEEE International Conference
on Formal Methods and Models for System Design, IEEE, 2020.
conference:
end_date: 2020-12-04
location: Virtual Conference
name: 'MEMOCODE: Conference on Formal Methods and Models for System Design'
start_date: 2020-12-02
date_created: 2020-11-10T07:04:57Z
date_published: 2020-12-04T00:00:00Z
date_updated: 2023-08-22T12:48:18Z
day: '04'
department:
- _id: ToHe
doi: 10.1109/MEMOCODE51338.2020.9314994
ec_funded: 1
external_id:
arxiv:
- '2006.12325'
isi:
- '000661920400013'
isi: 1
language:
- iso: eng
main_file_link:
- open_access: '1'
url: https://arxiv.org/abs/2006.12325
month: '12'
oa: 1
oa_version: Preprint
project:
- _id: 25F42A32-B435-11E9-9278-68D0E5697425
call_identifier: FWF
grant_number: Z211
name: The Wittgenstein Prize
- _id: 260C2330-B435-11E9-9278-68D0E5697425
call_identifier: H2020
grant_number: '754411'
name: ISTplus - Postdoctoral Fellowships
publication: 18th ACM-IEEE International Conference on Formal Methods and Models for
System Design
publication_identifier:
isbn:
- '9781728191485'
publication_status: published
publisher: IEEE
quality_controlled: '1'
scopus_import: '1'
status: public
title: Efficient reachability analysis of parametric linear hybrid systems with time-triggered
transitions
type: conference
user_id: 4359f0d1-fa6c-11eb-b949-802e58b17ae8
year: '2020'
...
---
_id: '8758'
abstract:
- lang: eng
text: We consider various modeling levels for spatially homogeneous chemical reaction
systems, namely the chemical master equation, the chemical Langevin dynamics,
and the reaction-rate equation. Throughout we restrict our study to the case where
the microscopic system satisfies the detailed-balance condition. The latter allows
us to enrich the systems with a gradient structure, i.e. the evolution is given
by a gradient-flow equation. We present the arising links between the associated
gradient structures that are driven by the relative entropy of the detailed-balance
steady state. The limit of large volumes is studied in the sense of evolutionary
Γ-convergence of gradient flows. Moreover, we use the gradient structures to derive
hybrid models for coupling different modeling levels.
acknowledgement: The research of A.M. was partially supported by the Deutsche Forschungsgemeinschaft
(DFG) via the Collaborative Research Center SFB 1114 Scaling Cascades in Complex
Systems (Project No. 235221301), through the Subproject C05 Effective models for
materials and interfaces with multiple scales. J.M. gratefully acknowledges support
by the European Research Council (ERC) under the European Union’s Horizon 2020 research
and innovation programme (Grant Agreement No. 716117), and by the Austrian Science
Fund (FWF), Project SFB F65. The authors thank Christof Schütte, Robert I. A. Patterson,
and Stefanie Winkelmann for helpful and stimulating discussions. Open access funding
provided by Austrian Science Fund (FWF).
article_processing_charge: No
article_type: original
author:
- first_name: Jan
full_name: Maas, Jan
id: 4C5696CE-F248-11E8-B48F-1D18A9856A87
last_name: Maas
orcid: 0000-0002-0845-1338
- first_name: Alexander
full_name: Mielke, Alexander
last_name: Mielke
citation:
ama: Maas J, Mielke A. Modeling of chemical reaction systems with detailed balance
using gradient structures. Journal of Statistical Physics. 2020;181(6):2257-2303.
doi:10.1007/s10955-020-02663-4
apa: Maas, J., & Mielke, A. (2020). Modeling of chemical reaction systems with
detailed balance using gradient structures. Journal of Statistical Physics.
Springer Nature. https://doi.org/10.1007/s10955-020-02663-4
chicago: Maas, Jan, and Alexander Mielke. “Modeling of Chemical Reaction Systems
with Detailed Balance Using Gradient Structures.” Journal of Statistical Physics.
Springer Nature, 2020. https://doi.org/10.1007/s10955-020-02663-4.
ieee: J. Maas and A. Mielke, “Modeling of chemical reaction systems with detailed
balance using gradient structures,” Journal of Statistical Physics, vol.
181, no. 6. Springer Nature, pp. 2257–2303, 2020.
ista: Maas J, Mielke A. 2020. Modeling of chemical reaction systems with detailed
balance using gradient structures. Journal of Statistical Physics. 181(6), 2257–2303.
mla: Maas, Jan, and Alexander Mielke. “Modeling of Chemical Reaction Systems with
Detailed Balance Using Gradient Structures.” Journal of Statistical Physics,
vol. 181, no. 6, Springer Nature, 2020, pp. 2257–303, doi:10.1007/s10955-020-02663-4.
short: J. Maas, A. Mielke, Journal of Statistical Physics 181 (2020) 2257–2303.
date_created: 2020-11-15T23:01:18Z
date_published: 2020-12-01T00:00:00Z
date_updated: 2023-08-22T13:24:27Z
day: '01'
ddc:
- '510'
department:
- _id: JaMa
doi: 10.1007/s10955-020-02663-4
ec_funded: 1
external_id:
arxiv:
- '2004.02831'
isi:
- '000587107200002'
file:
- access_level: open_access
checksum: bc2b63a90197b97cbc73eccada4639f5
content_type: application/pdf
creator: dernst
date_created: 2021-02-04T10:29:11Z
date_updated: 2021-02-04T10:29:11Z
file_id: '9087'
file_name: 2020_JourStatPhysics_Maas.pdf
file_size: 753596
relation: main_file
success: 1
file_date_updated: 2021-02-04T10:29:11Z
has_accepted_license: '1'
intvolume: ' 181'
isi: 1
issue: '6'
language:
- iso: eng
month: '12'
oa: 1
oa_version: Published Version
page: 2257-2303
project:
- _id: 256E75B8-B435-11E9-9278-68D0E5697425
call_identifier: H2020
grant_number: '716117'
name: Optimal Transport and Stochastic Dynamics
- _id: 260482E2-B435-11E9-9278-68D0E5697425
call_identifier: FWF
grant_number: ' F06504'
name: Taming Complexity in Partial Di erential Systems
publication: Journal of Statistical Physics
publication_identifier:
eissn:
- '15729613'
issn:
- '00224715'
publication_status: published
publisher: Springer Nature
quality_controlled: '1'
scopus_import: '1'
status: public
title: Modeling of chemical reaction systems with detailed balance using gradient
structures
tmp:
image: /images/cc_by.png
legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
short: CC BY (4.0)
type: journal_article
user_id: 4359f0d1-fa6c-11eb-b949-802e58b17ae8
volume: 181
year: '2020'
...
---
_id: '13070'
abstract:
- lang: eng
text: This dataset comprises all data shown in the figures of the submitted article
"Surpassing the resistance quantum with a geometric superinductor". Additional
raw data are available from the corresponding author on reasonable request.
article_processing_charge: No
author:
- first_name: Matilda
full_name: Peruzzo, Matilda
id: 3F920B30-F248-11E8-B48F-1D18A9856A87
last_name: Peruzzo
orcid: 0000-0002-3415-4628
- first_name: Andrea
full_name: Trioni, Andrea
id: 42F71B44-F248-11E8-B48F-1D18A9856A87
last_name: Trioni
- first_name: Farid
full_name: Hassani, Farid
id: 2AED110C-F248-11E8-B48F-1D18A9856A87
last_name: Hassani
orcid: 0000-0001-6937-5773
- first_name: Martin
full_name: Zemlicka, Martin
id: 2DCF8DE6-F248-11E8-B48F-1D18A9856A87
last_name: Zemlicka
- first_name: Johannes M
full_name: Fink, Johannes M
id: 4B591CBA-F248-11E8-B48F-1D18A9856A87
last_name: Fink
orcid: 0000-0001-8112-028X
citation:
ama: Peruzzo M, Trioni A, Hassani F, Zemlicka M, Fink JM. Surpassing the resistance
quantum with a geometric superinductor. 2020. doi:10.5281/ZENODO.4052882
apa: Peruzzo, M., Trioni, A., Hassani, F., Zemlicka, M., & Fink, J. M. (2020).
Surpassing the resistance quantum with a geometric superinductor. Zenodo. https://doi.org/10.5281/ZENODO.4052882
chicago: Peruzzo, Matilda, Andrea Trioni, Farid Hassani, Martin Zemlicka, and Johannes
M Fink. “Surpassing the Resistance Quantum with a Geometric Superinductor.” Zenodo,
2020. https://doi.org/10.5281/ZENODO.4052882.
ieee: M. Peruzzo, A. Trioni, F. Hassani, M. Zemlicka, and J. M. Fink, “Surpassing
the resistance quantum with a geometric superinductor.” Zenodo, 2020.
ista: Peruzzo M, Trioni A, Hassani F, Zemlicka M, Fink JM. 2020. Surpassing the
resistance quantum with a geometric superinductor, Zenodo, 10.5281/ZENODO.4052882.
mla: Peruzzo, Matilda, et al. Surpassing the Resistance Quantum with a Geometric
Superinductor. Zenodo, 2020, doi:10.5281/ZENODO.4052882.
short: M. Peruzzo, A. Trioni, F. Hassani, M. Zemlicka, J.M. Fink, (2020).
date_created: 2023-05-23T16:42:30Z
date_published: 2020-09-27T00:00:00Z
date_updated: 2023-08-22T13:23:57Z
day: '27'
ddc:
- '530'
department:
- _id: JoFi
doi: 10.5281/ZENODO.4052882
main_file_link:
- open_access: '1'
url: https://doi.org/10.5281/zenodo.4052883
month: '09'
oa: 1
oa_version: Published Version
publisher: Zenodo
related_material:
record:
- id: '8755'
relation: used_in_publication
status: public
status: public
title: Surpassing the resistance quantum with a geometric superinductor
tmp:
image: /images/cc_by.png
legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
short: CC BY (4.0)
type: research_data_reference
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
year: '2020'
...
---
_id: '8787'
abstract:
- lang: eng
text: Breakdown of vascular barriers is a major complication of inflammatory diseases.
Anucleate platelets form blood-clots during thrombosis, but also play a crucial
role in inflammation. While spatio-temporal dynamics of clot formation are well
characterized, the cell-biological mechanisms of platelet recruitment to inflammatory
micro-environments remain incompletely understood. Here we identify Arp2/3-dependent
lamellipodia formation as a prominent morphological feature of immune-responsive
platelets. Platelets use lamellipodia to scan for fibrin(ogen) deposited on the
inflamed vasculature and to directionally spread, to polarize and to govern haptotactic
migration along gradients of the adhesive ligand. Platelet-specific abrogation
of Arp2/3 interferes with haptotactic repositioning of platelets to microlesions,
thus impairing vascular sealing and provoking inflammatory microbleeding. During
infection, haptotaxis promotes capture of bacteria and prevents hematogenic dissemination,
rendering platelets gate-keepers of the inflamed microvasculature. Consequently,
these findings identify haptotaxis as a key effector function of immune-responsive
platelets.
acknowledgement: "We thank Sebastian Helmer, Nicole Blount, Christine Mann, and Beate
Jantz for technical assistance; Hellen Ishikawa-Ankerhold for help and advice; Michael
Sixt for critical\r\ndiscussions. This study was supported by the DFG SFB 914 (S.M.
[B02 and Z01], K.Sch.\r\n[B02], B.W. [A02 and Z03], C.A.R. [B03], C.S. [A10], J.P.
[Gerok position]), the DFG\r\nSFB 1123 (S.M. [B06]), the DFG FOR 2033 (S.M. and
F.G.), the German Center for\r\nCardiovascular Research (DZHK) (Clinician Scientist
Program [L.N.], MHA 1.4VD\r\n[S.M.], Postdoc Start-up Grant, 81×3600213 [F.G.]),
FP7 program (project 260309,\r\nPRESTIGE [S.M.]), FöFoLe project 1015/1009 (L.N.),
FöFoLe project 947 (F.G.), the\r\nFriedrich-Baur-Stiftung project 41/16 (F.G.),
and LMUexcellence NFF (F.G.). This project has received funding from the European
Research Council (ERC) under the European Union’s Horizon 2020 research and innovation
program (grant agreement no.\r\n833440) (S.M.). F.G. received funding from the European
Union’s Horizon 2020 research\r\nand innovation program under the Marie Skłodowska-Curie
grant agreement no.\r\n747687."
article_number: '5778'
article_processing_charge: No
article_type: original
author:
- first_name: Leo
full_name: Nicolai, Leo
last_name: Nicolai
- first_name: Karin
full_name: Schiefelbein, Karin
last_name: Schiefelbein
- first_name: Silvia
full_name: Lipsky, Silvia
last_name: Lipsky
- first_name: Alexander
full_name: Leunig, Alexander
last_name: Leunig
- first_name: Marie
full_name: Hoffknecht, Marie
last_name: Hoffknecht
- first_name: Kami
full_name: Pekayvaz, Kami
last_name: Pekayvaz
- first_name: Ben
full_name: Raude, Ben
last_name: Raude
- first_name: Charlotte
full_name: Marx, Charlotte
last_name: Marx
- first_name: Andreas
full_name: Ehrlich, Andreas
last_name: Ehrlich
- first_name: Joachim
full_name: Pircher, Joachim
last_name: Pircher
- first_name: Zhe
full_name: Zhang, Zhe
last_name: Zhang
- first_name: Inas
full_name: Saleh, Inas
last_name: Saleh
- first_name: Anna-Kristina
full_name: Marel, Anna-Kristina
last_name: Marel
- first_name: Achim
full_name: Löf, Achim
last_name: Löf
- first_name: Tobias
full_name: Petzold, Tobias
last_name: Petzold
- first_name: Michael
full_name: Lorenz, Michael
last_name: Lorenz
- first_name: Konstantin
full_name: Stark, Konstantin
last_name: Stark
- first_name: Robert
full_name: Pick, Robert
last_name: Pick
- first_name: Gerhild
full_name: Rosenberger, Gerhild
last_name: Rosenberger
- first_name: Ludwig
full_name: Weckbach, Ludwig
last_name: Weckbach
- first_name: Bernd
full_name: Uhl, Bernd
last_name: Uhl
- first_name: Sheng
full_name: Xia, Sheng
last_name: Xia
- first_name: Christoph Andreas
full_name: Reichel, Christoph Andreas
last_name: Reichel
- first_name: Barbara
full_name: Walzog, Barbara
last_name: Walzog
- first_name: Christian
full_name: Schulz, Christian
last_name: Schulz
- first_name: Vanessa
full_name: Zheden, Vanessa
id: 39C5A68A-F248-11E8-B48F-1D18A9856A87
last_name: Zheden
orcid: 0000-0002-9438-4783
- first_name: Markus
full_name: Bender, Markus
last_name: Bender
- first_name: Rong
full_name: Li, Rong
last_name: Li
- first_name: Steffen
full_name: Massberg, Steffen
last_name: Massberg
- first_name: Florian R
full_name: Gärtner, Florian R
id: 397A88EE-F248-11E8-B48F-1D18A9856A87
last_name: Gärtner
orcid: 0000-0001-6120-3723
citation:
ama: Nicolai L, Schiefelbein K, Lipsky S, et al. Vascular surveillance by haptotactic
blood platelets in inflammation and infection. Nature Communications. 2020;11.
doi:10.1038/s41467-020-19515-0
apa: Nicolai, L., Schiefelbein, K., Lipsky, S., Leunig, A., Hoffknecht, M., Pekayvaz,
K., … Gärtner, F. R. (2020). Vascular surveillance by haptotactic blood platelets
in inflammation and infection. Nature Communications. Springer Nature.
https://doi.org/10.1038/s41467-020-19515-0
chicago: Nicolai, Leo, Karin Schiefelbein, Silvia Lipsky, Alexander Leunig, Marie
Hoffknecht, Kami Pekayvaz, Ben Raude, et al. “Vascular Surveillance by Haptotactic
Blood Platelets in Inflammation and Infection.” Nature Communications.
Springer Nature, 2020. https://doi.org/10.1038/s41467-020-19515-0.
ieee: L. Nicolai et al., “Vascular surveillance by haptotactic blood platelets
in inflammation and infection,” Nature Communications, vol. 11. Springer
Nature, 2020.
ista: Nicolai L, Schiefelbein K, Lipsky S, Leunig A, Hoffknecht M, Pekayvaz K, Raude
B, Marx C, Ehrlich A, Pircher J, Zhang Z, Saleh I, Marel A-K, Löf A, Petzold T,
Lorenz M, Stark K, Pick R, Rosenberger G, Weckbach L, Uhl B, Xia S, Reichel CA,
Walzog B, Schulz C, Zheden V, Bender M, Li R, Massberg S, Gärtner FR. 2020. Vascular
surveillance by haptotactic blood platelets in inflammation and infection. Nature
Communications. 11, 5778.
mla: Nicolai, Leo, et al. “Vascular Surveillance by Haptotactic Blood Platelets
in Inflammation and Infection.” Nature Communications, vol. 11, 5778, Springer
Nature, 2020, doi:10.1038/s41467-020-19515-0.
short: L. Nicolai, K. Schiefelbein, S. Lipsky, A. Leunig, M. Hoffknecht, K. Pekayvaz,
B. Raude, C. Marx, A. Ehrlich, J. Pircher, Z. Zhang, I. Saleh, A.-K. Marel, A.
Löf, T. Petzold, M. Lorenz, K. Stark, R. Pick, G. Rosenberger, L. Weckbach, B.
Uhl, S. Xia, C.A. Reichel, B. Walzog, C. Schulz, V. Zheden, M. Bender, R. Li,
S. Massberg, F.R. Gärtner, Nature Communications 11 (2020).
date_created: 2020-11-22T23:01:23Z
date_published: 2020-11-13T00:00:00Z
date_updated: 2023-08-22T13:26:26Z
day: '13'
ddc:
- '570'
department:
- _id: MiSi
- _id: EM-Fac
doi: 10.1038/s41467-020-19515-0
ec_funded: 1
external_id:
isi:
- '000594648000014'
pmid:
- '33188196'
file:
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content_type: application/pdf
creator: dernst
date_created: 2020-11-23T13:29:49Z
date_updated: 2020-11-23T13:29:49Z
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intvolume: ' 11'
isi: 1
language:
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month: '11'
oa: 1
oa_version: Published Version
pmid: 1
project:
- _id: 260AA4E2-B435-11E9-9278-68D0E5697425
call_identifier: H2020
grant_number: '747687'
name: Mechanical Adaptation of Lamellipodial Actin Networks in Migrating Cells
publication: Nature Communications
publication_identifier:
eissn:
- '20411723'
publication_status: published
publisher: Springer Nature
quality_controlled: '1'
related_material:
link:
- relation: erratum
url: https://doi.org/10.1038/s41467-022-31310-7
scopus_import: '1'
status: public
title: Vascular surveillance by haptotactic blood platelets in inflammation and infection
tmp:
image: /images/cc_by.png
legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
short: CC BY (4.0)
type: journal_article
user_id: 4359f0d1-fa6c-11eb-b949-802e58b17ae8
volume: 11
year: '2020'
...
---
_id: '8789'
abstract:
- lang: eng
text: Cooperation is a ubiquitous and beneficial behavioural trait despite being
prone to exploitation by free-riders. Hence, cooperative populations are prone
to invasions by selfish individuals. However, a population consisting of only
free-riders typically does not survive. Thus, cooperators and free-riders often
coexist in some proportion. An evolutionary version of a Snowdrift Game proved
its efficiency in analysing this phenomenon. However, what if the system has already
reached its stable state but was perturbed due to a change in environmental conditions?
Then, individuals may have to re-learn their effective strategies. To address
this, we consider behavioural mistakes in strategic choice execution, which we
refer to as incompetence. Parametrising the propensity to make such mistakes allows
for a mathematical description of learning. We compare strategies based on their
relative strategic advantage relying on both fitness and learning factors. When
strategies are learned at distinct rates, allowing learning according to a prescribed
order is optimal. Interestingly, the strategy with the lowest strategic advantage
should be learnt first if we are to optimise fitness over the learning path. Then,
the differences between strategies are balanced out in order to minimise the effect
of behavioural uncertainty.
acknowledgement: "This work was supported by the European Union’s Horizon 2020 research
and innovation program under the Marie Sklodowska-Curie Grant Agreement #754411,
the Australian Research Council Discovery Grants DP160101236 and DP150100618, and
the European Research Council Consolidator Grant 863818 (FoRM-SMArt).\r\nAuthors
would like to thank Patrick McKinlay for his work on the preliminary results for
this paper."
article_number: '1945'
article_processing_charge: No
article_type: original
author:
- first_name: Maria
full_name: Kleshnina, Maria
id: 4E21749C-F248-11E8-B48F-1D18A9856A87
last_name: Kleshnina
- first_name: Sabrina
full_name: Streipert, Sabrina
last_name: Streipert
- first_name: Jerzy
full_name: Filar, Jerzy
last_name: Filar
- first_name: Krishnendu
full_name: Chatterjee, Krishnendu
id: 2E5DCA20-F248-11E8-B48F-1D18A9856A87
last_name: Chatterjee
orcid: 0000-0002-4561-241X
citation:
ama: Kleshnina M, Streipert S, Filar J, Chatterjee K. Prioritised learning in snowdrift-type
games. Mathematics. 2020;8(11). doi:10.3390/math8111945
apa: Kleshnina, M., Streipert, S., Filar, J., & Chatterjee, K. (2020). Prioritised
learning in snowdrift-type games. Mathematics. MDPI. https://doi.org/10.3390/math8111945
chicago: Kleshnina, Maria, Sabrina Streipert, Jerzy Filar, and Krishnendu Chatterjee.
“Prioritised Learning in Snowdrift-Type Games.” Mathematics. MDPI, 2020.
https://doi.org/10.3390/math8111945.
ieee: M. Kleshnina, S. Streipert, J. Filar, and K. Chatterjee, “Prioritised learning
in snowdrift-type games,” Mathematics, vol. 8, no. 11. MDPI, 2020.
ista: Kleshnina M, Streipert S, Filar J, Chatterjee K. 2020. Prioritised learning
in snowdrift-type games. Mathematics. 8(11), 1945.
mla: Kleshnina, Maria, et al. “Prioritised Learning in Snowdrift-Type Games.” Mathematics,
vol. 8, no. 11, 1945, MDPI, 2020, doi:10.3390/math8111945.
short: M. Kleshnina, S. Streipert, J. Filar, K. Chatterjee, Mathematics 8 (2020).
date_created: 2020-11-22T23:01:24Z
date_published: 2020-11-04T00:00:00Z
date_updated: 2023-08-22T13:25:45Z
day: '04'
ddc:
- '000'
department:
- _id: KrCh
doi: 10.3390/math8111945
ec_funded: 1
external_id:
isi:
- '000593962100001'
file:
- access_level: open_access
checksum: 61cfcc3b35760656ce7a9385a4ace5d2
content_type: application/pdf
creator: dernst
date_created: 2020-11-23T13:06:30Z
date_updated: 2020-11-23T13:06:30Z
file_id: '8797'
file_name: 2020_Mathematics_Kleshnina.pdf
file_size: 565191
relation: main_file
success: 1
file_date_updated: 2020-11-23T13:06:30Z
has_accepted_license: '1'
intvolume: ' 8'
isi: 1
issue: '11'
language:
- iso: eng
month: '11'
oa: 1
oa_version: Published Version
project:
- _id: 260C2330-B435-11E9-9278-68D0E5697425
call_identifier: H2020
grant_number: '754411'
name: ISTplus - Postdoctoral Fellowships
- _id: 0599E47C-7A3F-11EA-A408-12923DDC885E
call_identifier: H2020
grant_number: '863818'
name: 'Formal Methods for Stochastic Models: Algorithms and Applications'
publication: Mathematics
publication_identifier:
eissn:
- '22277390'
publication_status: published
publisher: MDPI
quality_controlled: '1'
scopus_import: '1'
status: public
title: Prioritised learning in snowdrift-type games
tmp:
image: /images/cc_by.png
legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
short: CC BY (4.0)
type: journal_article
user_id: 4359f0d1-fa6c-11eb-b949-802e58b17ae8
volume: 8
year: '2020'
...
---
_id: '8287'
abstract:
- lang: eng
text: Reachability analysis aims at identifying states reachable by a system within
a given time horizon. This task is known to be computationally expensive for linear
hybrid systems. Reachability analysis works by iteratively applying continuous
and discrete post operators to compute states reachable according to continuous
and discrete dynamics, respectively. In this paper, we enhance both of these operators
and make sure that most of the involved computations are performed in low-dimensional
state space. In particular, we improve the continuous-post operator by performing
computations in high-dimensional state space only for time intervals relevant
for the subsequent application of the discrete-post operator. Furthermore, the
new discrete-post operator performs low-dimensional computations by leveraging
the structure of the guard and assignment of a considered transition. We illustrate
the potential of our approach on a number of challenging benchmarks.
article_processing_charge: No
author:
- first_name: Sergiy
full_name: Bogomolov, Sergiy
last_name: Bogomolov
- first_name: Marcelo
full_name: Forets, Marcelo
last_name: Forets
- first_name: Goran
full_name: Frehse, Goran
last_name: Frehse
- first_name: Kostiantyn
full_name: Potomkin, Kostiantyn
last_name: Potomkin
- first_name: Christian
full_name: Schilling, Christian
id: 3A2F4DCE-F248-11E8-B48F-1D18A9856A87
last_name: Schilling
orcid: 0000-0003-3658-1065
citation:
ama: 'Bogomolov S, Forets M, Frehse G, Potomkin K, Schilling C. Reachability analysis
of linear hybrid systems via block decomposition. In: Proceedings of the International
Conference on Embedded Software. ; 2020.'
apa: Bogomolov, S., Forets, M., Frehse, G., Potomkin, K., & Schilling, C. (2020).
Reachability analysis of linear hybrid systems via block decomposition. In Proceedings
of the International Conference on Embedded Software. Virtual .
chicago: Bogomolov, Sergiy, Marcelo Forets, Goran Frehse, Kostiantyn Potomkin, and
Christian Schilling. “Reachability Analysis of Linear Hybrid Systems via Block
Decomposition.” In Proceedings of the International Conference on Embedded
Software, 2020.
ieee: S. Bogomolov, M. Forets, G. Frehse, K. Potomkin, and C. Schilling, “Reachability
analysis of linear hybrid systems via block decomposition,” in Proceedings
of the International Conference on Embedded Software, Virtual , 2020.
ista: 'Bogomolov S, Forets M, Frehse G, Potomkin K, Schilling C. 2020. Reachability
analysis of linear hybrid systems via block decomposition. Proceedings of the
International Conference on Embedded Software. EMSOFT: International Conference
on Embedded Software.'
mla: Bogomolov, Sergiy, et al. “Reachability Analysis of Linear Hybrid Systems via
Block Decomposition.” Proceedings of the International Conference on Embedded
Software, 2020.
short: S. Bogomolov, M. Forets, G. Frehse, K. Potomkin, C. Schilling, in:, Proceedings
of the International Conference on Embedded Software, 2020.
conference:
end_date: 2020-09-25
location: 'Virtual '
name: 'EMSOFT: International Conference on Embedded Software'
start_date: 2020-09-20
date_created: 2020-08-24T12:56:20Z
date_published: 2020-01-01T00:00:00Z
date_updated: 2023-08-22T13:27:32Z
ddc:
- '000'
department:
- _id: ToHe
ec_funded: 1
external_id:
arxiv:
- '1905.02458'
file:
- access_level: open_access
checksum: d19e97d0f8a3a441dc078ec812297d75
content_type: application/pdf
creator: cschilli
date_created: 2020-08-24T12:53:15Z
date_updated: 2020-08-24T12:53:15Z
file_id: '8288'
file_name: 2020EMSOFT.pdf
file_size: 696384
relation: main_file
success: 1
file_date_updated: 2020-08-24T12:53:15Z
has_accepted_license: '1'
keyword:
- reachability
- hybrid systems
- decomposition
language:
- iso: eng
oa: 1
oa_version: Preprint
project:
- _id: 25832EC2-B435-11E9-9278-68D0E5697425
call_identifier: FWF
grant_number: S 11407_N23
name: Rigorous Systems Engineering
- _id: 25C5A090-B435-11E9-9278-68D0E5697425
call_identifier: FWF
grant_number: Z00312
name: The Wittgenstein Prize
- _id: 260C2330-B435-11E9-9278-68D0E5697425
call_identifier: H2020
grant_number: '754411'
name: ISTplus - Postdoctoral Fellowships
publication: Proceedings of the International Conference on Embedded Software
publication_status: published
quality_controlled: '1'
related_material:
record:
- id: '8790'
relation: later_version
status: public
status: public
title: Reachability analysis of linear hybrid systems via block decomposition
tmp:
image: /images/cc_by.png
legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
short: CC BY (4.0)
type: conference
user_id: 8b945eb4-e2f2-11eb-945a-df72226e66a9
year: '2020'
...
---
_id: '8788'
abstract:
- lang: eng
text: 'We consider a real-time setting where an environment releases sequences of
firm-deadline tasks, and an online scheduler chooses on-the-fly the ones to execute
on a single processor so as to maximize cumulated utility. The competitive ratio
is a well-known performance measure for the scheduler: it gives the worst-case
ratio, among all possible choices for the environment, of the cumulated utility
of the online scheduler versus an offline scheduler that knows these choices in
advance. Traditionally, competitive analysis is performed by hand, while automated
techniques are rare and only handle static environments with independent tasks.
We present a quantitative-verification framework for precedence-aware competitive
analysis, where task releases may depend on preceding scheduling choices, i.e.,
the environment can respond to scheduling decisions dynamically . We consider
two general classes of precedences: 1) follower precedences force the release
of a dependent task upon the completion of a set of precursor tasks, while and
2) pairing precedences modify the characteristics of a dependent task provided
the completion of a set of precursor tasks. Precedences make competitive analysis
challenging, as the online and offline schedulers operate on diverging sequences.
We make a formal presentation of our framework, and use a GPU-based implementation
to analyze ten well-known schedulers on precedence-based application examples
taken from the existing literature: 1) a handshake protocol (HP); 2) network packet-switching;
3) query scheduling (QS); and 4) a sporadic-interrupt setting. Our experimental
results show that precedences and task parameters can vary drastically the best
scheduler. Our framework thus supports application designers in choosing the best
scheduler among a given set automatically.'
acknowledgement: 'This work was supported by the Austrian Science Foundation (FWF)
under the NFN RiSE/SHiNE under Grant S11405 and Grant S11407. This article was presented
in the International Conference on Embedded Software 2020 and appears as part of
the ESWEEK-TCAD special issue. '
article_processing_charge: No
article_type: original
author:
- first_name: Andreas
full_name: Pavlogiannis, Andreas
id: 49704004-F248-11E8-B48F-1D18A9856A87
last_name: Pavlogiannis
orcid: 0000-0002-8943-0722
- first_name: Nico
full_name: Schaumberger, Nico
last_name: Schaumberger
- first_name: Ulrich
full_name: Schmid, Ulrich
last_name: Schmid
- first_name: Krishnendu
full_name: Chatterjee, Krishnendu
id: 2E5DCA20-F248-11E8-B48F-1D18A9856A87
last_name: Chatterjee
orcid: 0000-0002-4561-241X
citation:
ama: Pavlogiannis A, Schaumberger N, Schmid U, Chatterjee K. Precedence-aware automated
competitive analysis of real-time scheduling. IEEE Transactions on Computer-Aided
Design of Integrated Circuits and Systems. 2020;39(11):3981-3992. doi:10.1109/TCAD.2020.3012803
apa: Pavlogiannis, A., Schaumberger, N., Schmid, U., & Chatterjee, K. (2020).
Precedence-aware automated competitive analysis of real-time scheduling. IEEE
Transactions on Computer-Aided Design of Integrated Circuits and Systems.
IEEE. https://doi.org/10.1109/TCAD.2020.3012803
chicago: Pavlogiannis, Andreas, Nico Schaumberger, Ulrich Schmid, and Krishnendu
Chatterjee. “Precedence-Aware Automated Competitive Analysis of Real-Time Scheduling.”
IEEE Transactions on Computer-Aided Design of Integrated Circuits and Systems.
IEEE, 2020. https://doi.org/10.1109/TCAD.2020.3012803.
ieee: A. Pavlogiannis, N. Schaumberger, U. Schmid, and K. Chatterjee, “Precedence-aware
automated competitive analysis of real-time scheduling,” IEEE Transactions
on Computer-Aided Design of Integrated Circuits and Systems, vol. 39, no.
11. IEEE, pp. 3981–3992, 2020.
ista: Pavlogiannis A, Schaumberger N, Schmid U, Chatterjee K. 2020. Precedence-aware
automated competitive analysis of real-time scheduling. IEEE Transactions on Computer-Aided
Design of Integrated Circuits and Systems. 39(11), 3981–3992.
mla: Pavlogiannis, Andreas, et al. “Precedence-Aware Automated Competitive Analysis
of Real-Time Scheduling.” IEEE Transactions on Computer-Aided Design of Integrated
Circuits and Systems, vol. 39, no. 11, IEEE, 2020, pp. 3981–92, doi:10.1109/TCAD.2020.3012803.
short: A. Pavlogiannis, N. Schaumberger, U. Schmid, K. Chatterjee, IEEE Transactions
on Computer-Aided Design of Integrated Circuits and Systems 39 (2020) 3981–3992.
date_created: 2020-11-22T23:01:24Z
date_published: 2020-11-01T00:00:00Z
date_updated: 2023-08-22T13:27:05Z
day: '01'
department:
- _id: KrCh
doi: 10.1109/TCAD.2020.3012803
external_id:
isi:
- '000587712700069'
intvolume: ' 39'
isi: 1
issue: '11'
language:
- iso: eng
month: '11'
oa_version: None
page: 3981-3992
project:
- _id: 25832EC2-B435-11E9-9278-68D0E5697425
call_identifier: FWF
grant_number: S 11407_N23
name: Rigorous Systems Engineering
- _id: 25863FF4-B435-11E9-9278-68D0E5697425
call_identifier: FWF
grant_number: S11407
name: Game Theory
publication: IEEE Transactions on Computer-Aided Design of Integrated Circuits and
Systems
publication_identifier:
eissn:
- '19374151'
issn:
- '02780070'
publication_status: published
publisher: IEEE
quality_controlled: '1'
scopus_import: '1'
status: public
title: Precedence-aware automated competitive analysis of real-time scheduling
type: journal_article
user_id: 4359f0d1-fa6c-11eb-b949-802e58b17ae8
volume: 39
year: '2020'
...
---
_id: '8790'
abstract:
- lang: eng
text: Reachability analysis aims at identifying states reachable by a system within
a given time horizon. This task is known to be computationally expensive for linear
hybrid systems. Reachability analysis works by iteratively applying continuous
and discrete post operators to compute states reachable according to continuous
and discrete dynamics, respectively. In this article, we enhance both of these
operators and make sure that most of the involved computations are performed in
low-dimensional state space. In particular, we improve the continuous-post operator
by performing computations in high-dimensional state space only for time intervals
relevant for the subsequent application of the discrete-post operator. Furthermore,
the new discrete-post operator performs low-dimensional computations by leveraging
the structure of the guard and assignment of a considered transition. We illustrate
the potential of our approach on a number of challenging benchmarks.
acknowledgement: 'This research was supported in part by the Austrian Science Fund
(FWF) under grants S11402-N23 (RiSE/SHiNE) and Z211-N23 (Wittgenstein Award), the
European Union’s Horizon 2020 research and innovation programme under the Marie
Skłodowska-Curie grant agreement No. 754411, and the Air Force Office of Scientific
Research under award number FA2386-17-1-4065. Any opinions, findings, and conclusions
or recommendations expressed in this material are those of the authors and do not
necessarily reflect the views of the United States Air Force. '
article_processing_charge: No
article_type: original
author:
- first_name: Sergiy
full_name: Bogomolov, Sergiy
id: 369D9A44-F248-11E8-B48F-1D18A9856A87
last_name: Bogomolov
orcid: 0000-0002-0686-0365
- first_name: Marcelo
full_name: Forets, Marcelo
last_name: Forets
- first_name: Goran
full_name: Frehse, Goran
last_name: Frehse
- first_name: Kostiantyn
full_name: Potomkin, Kostiantyn
last_name: Potomkin
- first_name: Christian
full_name: Schilling, Christian
id: 3A2F4DCE-F248-11E8-B48F-1D18A9856A87
last_name: Schilling
orcid: 0000-0003-3658-1065
citation:
ama: Bogomolov S, Forets M, Frehse G, Potomkin K, Schilling C. Reachability analysis
of linear hybrid systems via block decomposition. IEEE Transactions on Computer-Aided
Design of Integrated Circuits and Systems. 2020;39(11):4018-4029. doi:10.1109/TCAD.2020.3012859
apa: Bogomolov, S., Forets, M., Frehse, G., Potomkin, K., & Schilling, C. (2020).
Reachability analysis of linear hybrid systems via block decomposition. IEEE
Transactions on Computer-Aided Design of Integrated Circuits and Systems.
IEEE. https://doi.org/10.1109/TCAD.2020.3012859
chicago: Bogomolov, Sergiy, Marcelo Forets, Goran Frehse, Kostiantyn Potomkin, and
Christian Schilling. “Reachability Analysis of Linear Hybrid Systems via Block
Decomposition.” IEEE Transactions on Computer-Aided Design of Integrated Circuits
and Systems. IEEE, 2020. https://doi.org/10.1109/TCAD.2020.3012859.
ieee: S. Bogomolov, M. Forets, G. Frehse, K. Potomkin, and C. Schilling, “Reachability
analysis of linear hybrid systems via block decomposition,” IEEE Transactions
on Computer-Aided Design of Integrated Circuits and Systems, vol. 39, no.
11. IEEE, pp. 4018–4029, 2020.
ista: Bogomolov S, Forets M, Frehse G, Potomkin K, Schilling C. 2020. Reachability
analysis of linear hybrid systems via block decomposition. IEEE Transactions on
Computer-Aided Design of Integrated Circuits and Systems. 39(11), 4018–4029.
mla: Bogomolov, Sergiy, et al. “Reachability Analysis of Linear Hybrid Systems via
Block Decomposition.” IEEE Transactions on Computer-Aided Design of Integrated
Circuits and Systems, vol. 39, no. 11, IEEE, 2020, pp. 4018–29, doi:10.1109/TCAD.2020.3012859.
short: S. Bogomolov, M. Forets, G. Frehse, K. Potomkin, C. Schilling, IEEE Transactions
on Computer-Aided Design of Integrated Circuits and Systems 39 (2020) 4018–4029.
date_created: 2020-11-22T23:01:25Z
date_published: 2020-11-01T00:00:00Z
date_updated: 2023-08-22T13:27:33Z
day: '01'
department:
- _id: ToHe
doi: 10.1109/TCAD.2020.3012859
ec_funded: 1
external_id:
arxiv:
- '1905.02458'
isi:
- '000587712700072'
intvolume: ' 39'
isi: 1
issue: '11'
language:
- iso: eng
main_file_link:
- open_access: '1'
url: https://arxiv.org/abs/1905.02458
month: '11'
oa: 1
oa_version: Preprint
page: 4018-4029
project:
- _id: 25832EC2-B435-11E9-9278-68D0E5697425
call_identifier: FWF
grant_number: S 11407_N23
name: Rigorous Systems Engineering
- _id: 25F42A32-B435-11E9-9278-68D0E5697425
call_identifier: FWF
grant_number: Z211
name: The Wittgenstein Prize
- _id: 260C2330-B435-11E9-9278-68D0E5697425
call_identifier: H2020
grant_number: '754411'
name: ISTplus - Postdoctoral Fellowships
publication: IEEE Transactions on Computer-Aided Design of Integrated Circuits and
Systems
publication_identifier:
eissn:
- '19374151'
issn:
- '02780070'
publication_status: published
publisher: IEEE
quality_controlled: '1'
related_material:
record:
- id: '8287'
relation: earlier_version
status: public
scopus_import: '1'
status: public
title: Reachability analysis of linear hybrid systems via block decomposition
type: journal_article
user_id: 4359f0d1-fa6c-11eb-b949-802e58b17ae8
volume: 39
year: '2020'
...
---
_id: '8924'
abstract:
- lang: eng
text: 'Maintaining fertility in a fluctuating environment is key to the reproductive
success of flowering plants. Meiosis and pollen formation are particularly sensitive
to changes in growing conditions, especially temperature. We have previously identified
cyclin-dependent kinase G1 (CDKG1) as a master regulator of temperature-dependent
meiosis and this may involve the regulation of alternative splicing (AS), including
of its own transcript. CDKG1 mRNA can undergo several AS events, potentially producing
two protein variants: CDKG1L and CDKG1S, differing in their N-terminal domain
which may be involved in co-factor interaction. In leaves, both isoforms have
distinct temperature-dependent functions on target mRNA processing, but their
role in pollen development is unknown. In the present study, we characterize the
role of CDKG1L and CDKG1S in maintaining Arabidopsis fertility. We show that the
long (L) form is necessary and sufficient to rescue the fertility defects of the
cdkg1-1 mutant, while the short (S) form is unable to rescue fertility. On the
other hand, an extra copy of CDKG1L reduces fertility. In addition, mutation of
the ATP binding pocket of the kinase indicates that kinase activity is necessary
for the function of CDKG1. Kinase mutants of CDKG1L and CDKG1S correctly localize
to the cell nucleus and nucleus and cytoplasm, respectively, but are unable to
rescue either the fertility or the splicing defects of the cdkg1-1 mutant. Furthermore,
we show that there is partial functional overlap between CDKG1 and its paralog
CDKG2 that could in part be explained by overlapping gene expression.'
acknowledgement: CN, DD, NF-F, and JD were funded by the BBSRC (grant number BB/M009459/1).
NK and AM were funded through the ERASMUS+Program. NC was funded by the VIPS Program
of the Austrian Federal Ministry of Science and Research and the City of Vienna.
article_number: '586870'
article_processing_charge: No
article_type: original
author:
- first_name: Candida
full_name: Nibau, Candida
last_name: Nibau
- first_name: Despoina
full_name: Dadarou, Despoina
last_name: Dadarou
- first_name: Nestoras
full_name: Kargios, Nestoras
last_name: Kargios
- first_name: Areti
full_name: Mallioura, Areti
last_name: Mallioura
- first_name: Narcis
full_name: Fernandez-Fuentes, Narcis
last_name: Fernandez-Fuentes
- first_name: Nicola
full_name: Cavallari, Nicola
id: 457160E6-F248-11E8-B48F-1D18A9856A87
last_name: Cavallari
- first_name: John H.
full_name: Doonan, John H.
last_name: Doonan
citation:
ama: Nibau C, Dadarou D, Kargios N, et al. A functional kinase is necessary for
cyclin-dependent kinase G1 (CDKG1) to maintain fertility at high ambient temperature
in Arabidopsis. Frontiers in Plant Science. 2020;11. doi:10.3389/fpls.2020.586870
apa: Nibau, C., Dadarou, D., Kargios, N., Mallioura, A., Fernandez-Fuentes, N.,
Cavallari, N., & Doonan, J. H. (2020). A functional kinase is necessary for
cyclin-dependent kinase G1 (CDKG1) to maintain fertility at high ambient temperature
in Arabidopsis. Frontiers in Plant Science. Frontiers. https://doi.org/10.3389/fpls.2020.586870
chicago: Nibau, Candida, Despoina Dadarou, Nestoras Kargios, Areti Mallioura, Narcis
Fernandez-Fuentes, Nicola Cavallari, and John H. Doonan. “A Functional Kinase
Is Necessary for Cyclin-Dependent Kinase G1 (CDKG1) to Maintain Fertility at High
Ambient Temperature in Arabidopsis.” Frontiers in Plant Science. Frontiers,
2020. https://doi.org/10.3389/fpls.2020.586870.
ieee: C. Nibau et al., “A functional kinase is necessary for cyclin-dependent
kinase G1 (CDKG1) to maintain fertility at high ambient temperature in Arabidopsis,”
Frontiers in Plant Science, vol. 11. Frontiers, 2020.
ista: Nibau C, Dadarou D, Kargios N, Mallioura A, Fernandez-Fuentes N, Cavallari
N, Doonan JH. 2020. A functional kinase is necessary for cyclin-dependent kinase
G1 (CDKG1) to maintain fertility at high ambient temperature in Arabidopsis. Frontiers
in Plant Science. 11, 586870.
mla: Nibau, Candida, et al. “A Functional Kinase Is Necessary for Cyclin-Dependent
Kinase G1 (CDKG1) to Maintain Fertility at High Ambient Temperature in Arabidopsis.”
Frontiers in Plant Science, vol. 11, 586870, Frontiers, 2020, doi:10.3389/fpls.2020.586870.
short: C. Nibau, D. Dadarou, N. Kargios, A. Mallioura, N. Fernandez-Fuentes, N.
Cavallari, J.H. Doonan, Frontiers in Plant Science 11 (2020).
date_created: 2020-12-06T23:01:14Z
date_published: 2020-11-10T00:00:00Z
date_updated: 2023-08-24T10:50:00Z
day: '10'
ddc:
- '580'
department:
- _id: EvBe
doi: 10.3389/fpls.2020.586870
external_id:
isi:
- '000591637000001'
file:
- access_level: open_access
checksum: 1c0ee6ce9950aa665d6a5cc64aa6b752
content_type: application/pdf
creator: dernst
date_created: 2020-12-09T09:14:19Z
date_updated: 2020-12-09T09:14:19Z
file_id: '8929'
file_name: 2020_Frontiers_Nibau.pdf
file_size: 1833244
relation: main_file
success: 1
file_date_updated: 2020-12-09T09:14:19Z
has_accepted_license: '1'
intvolume: ' 11'
isi: 1
language:
- iso: eng
month: '11'
oa: 1
oa_version: Published Version
publication: Frontiers in Plant Science
publication_identifier:
eissn:
- 1664-462X
publication_status: published
publisher: Frontiers
quality_controlled: '1'
scopus_import: '1'
status: public
title: A functional kinase is necessary for cyclin-dependent kinase G1 (CDKG1) to
maintain fertility at high ambient temperature in Arabidopsis
tmp:
image: /images/cc_by.png
legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
short: CC BY (4.0)
type: journal_article
user_id: 4359f0d1-fa6c-11eb-b949-802e58b17ae8
volume: 11
year: '2020'
...
---
_id: '8926'
abstract:
- lang: eng
text: 'Bimetallic nanoparticles with tailored size and specific composition have
shown promise as stable and selective catalysts for electrochemical reduction
of CO2 (CO2R) in batch systems. Yet, limited effort was devoted to understand
the effect of ligand coverage and postsynthesis treatments on CO2 reduction, especially
under industrially applicable conditions, such as at high currents (>100 mA/cm2)
using gas diffusion electrodes (GDE) and flow reactors. In this work, Cu–Ag core–shell
nanoparticles (11 ± 2 nm) were prepared with three different surface modes: (i)
capped with oleylamine, (ii) capped with monoisopropylamine, and (iii) surfactant-free
with a reducing borohydride agent; Cu–Ag (OAm), Cu–Ag (MIPA), and Cu–Ag (NaBH4),
respectively. The ligand exchange and removal was evidenced by infrared spectroscopy
(ATR-FTIR) analysis, whereas high-resolution scanning transmission electron microscopy
(HAADF-STEM) showed their effect on the interparticle distance and nanoparticle
rearrangement. Later on, we developed a process-on-substrate method to track these
effects on CO2R. Cu–Ag (OAm) gave a lower on-set potential for hydrocarbon production,
whereas Cu–Ag (MIPA) and Cu–Ag (NaBH4) promoted syngas production. The electrochemical
impedance and surface area analysis on the well-controlled electrodes showed gradual
increases in the electrical conductivity and active surface area after each surface
treatment. We found that the increasing amount of the triple phase boundaries
(the meeting point for the electron–electrolyte–CO2 reactant) affect the required
electrode potential and eventually the C+2e̅/C2e̅ product ratio. This study highlights
the importance of the electron transfer to those active sites affected by the
capping agents—particularly on larger substrates that are crucial for their industrial
application.'
acknowledgement: The authors also acknowledge financial support from the University
Research Fund (BOF-GOA-PS ID No. 33928). S.L. has received funding from the European
Union’s Horizon 2020 research and innovation program under the Marie Skłodowska-Curie
Grant Agreement No. 665385.
article_processing_charge: No
article_type: original
author:
- first_name: Erdem
full_name: Irtem, Erdem
last_name: Irtem
- first_name: Daniel
full_name: Arenas Esteban, Daniel
last_name: Arenas Esteban
- first_name: Miguel
full_name: Duarte, Miguel
last_name: Duarte
- first_name: Daniel
full_name: Choukroun, Daniel
last_name: Choukroun
- first_name: Seungho
full_name: Lee, Seungho
id: BB243B88-D767-11E9-B658-BC13E6697425
last_name: Lee
orcid: 0000-0002-6962-8598
- first_name: Maria
full_name: Ibáñez, Maria
id: 43C61214-F248-11E8-B48F-1D18A9856A87
last_name: Ibáñez
orcid: 0000-0001-5013-2843
- first_name: Sara
full_name: Bals, Sara
last_name: Bals
- first_name: Tom
full_name: Breugelmans, Tom
last_name: Breugelmans
citation:
ama: Irtem E, Arenas Esteban D, Duarte M, et al. Ligand-mode directed selectivity
in Cu-Ag core-shell based gas diffusion electrodes for CO2 electroreduction. ACS
Catalysis. 2020;10(22):13468-13478. doi:10.1021/acscatal.0c03210
apa: Irtem, E., Arenas Esteban, D., Duarte, M., Choukroun, D., Lee, S., Ibáñez,
M., … Breugelmans, T. (2020). Ligand-mode directed selectivity in Cu-Ag core-shell
based gas diffusion electrodes for CO2 electroreduction. ACS Catalysis.
American Chemical Society. https://doi.org/10.1021/acscatal.0c03210
chicago: Irtem, Erdem, Daniel Arenas Esteban, Miguel Duarte, Daniel Choukroun, Seungho
Lee, Maria Ibáñez, Sara Bals, and Tom Breugelmans. “Ligand-Mode Directed Selectivity
in Cu-Ag Core-Shell Based Gas Diffusion Electrodes for CO2 Electroreduction.”
ACS Catalysis. American Chemical Society, 2020. https://doi.org/10.1021/acscatal.0c03210.
ieee: E. Irtem et al., “Ligand-mode directed selectivity in Cu-Ag core-shell
based gas diffusion electrodes for CO2 electroreduction,” ACS Catalysis,
vol. 10, no. 22. American Chemical Society, pp. 13468–13478, 2020.
ista: Irtem E, Arenas Esteban D, Duarte M, Choukroun D, Lee S, Ibáñez M, Bals S,
Breugelmans T. 2020. Ligand-mode directed selectivity in Cu-Ag core-shell based
gas diffusion electrodes for CO2 electroreduction. ACS Catalysis. 10(22), 13468–13478.
mla: Irtem, Erdem, et al. “Ligand-Mode Directed Selectivity in Cu-Ag Core-Shell
Based Gas Diffusion Electrodes for CO2 Electroreduction.” ACS Catalysis,
vol. 10, no. 22, American Chemical Society, 2020, pp. 13468–78, doi:10.1021/acscatal.0c03210.
short: E. Irtem, D. Arenas Esteban, M. Duarte, D. Choukroun, S. Lee, M. Ibáñez,
S. Bals, T. Breugelmans, ACS Catalysis 10 (2020) 13468–13478.
date_created: 2020-12-06T23:01:15Z
date_published: 2020-11-20T00:00:00Z
date_updated: 2023-08-24T10:52:32Z
day: '20'
department:
- _id: MaIb
doi: 10.1021/acscatal.0c03210
ec_funded: 1
external_id:
isi:
- '000592978900031'
intvolume: ' 10'
isi: 1
issue: '22'
language:
- iso: eng
month: '11'
oa_version: None
page: 13468-13478
project:
- _id: 2564DBCA-B435-11E9-9278-68D0E5697425
call_identifier: H2020
grant_number: '665385'
name: International IST Doctoral Program
publication: ACS Catalysis
publication_identifier:
eissn:
- '21555435'
publication_status: published
publisher: American Chemical Society
quality_controlled: '1'
scopus_import: '1'
status: public
title: Ligand-mode directed selectivity in Cu-Ag core-shell based gas diffusion electrodes
for CO2 electroreduction
type: journal_article
user_id: 4359f0d1-fa6c-11eb-b949-802e58b17ae8
volume: 10
year: '2020'
...
---
_id: '8944'
abstract:
- lang: eng
text: "Superconductor insulator transition in transverse magnetic field is studied
in the highly disordered MoC film with the product of the Fermi momentum and the
mean free path kF*l close to unity. Surprisingly, the Zeeman paramagnetic effects
dominate over orbital coupling on both sides of the transition. In superconducting
state it is evidenced by a high upper critical magnetic field \U0001D435\U0001D4502,
by its square root dependence on temperature, as well as by the Zeeman splitting
of the quasiparticle density of states (DOS) measured by scanning tunneling microscopy.
At \U0001D435\U0001D4502 a logarithmic anomaly in DOS is observed. This anomaly
is further enhanced in increasing magnetic field, which is explained by the Zeeman
splitting of the Altshuler-Aronov DOS driving\r\nthe system into a more insulating
or resistive state. Spin dependent Altshuler-Aronov correction is also needed
to explain the transport behavior above \U0001D435\U0001D4502."
acknowledgement: 'We gratefully acknowledge helpful conversations with B.L. Altshuler
and R. Hlubina. The work was supported by the projects APVV-18-0358, VEGA 2/0058/20,
VEGA 1/0743/19 the European Microkelvin Platform, the COST action CA16218 (Nanocohybri)
and by U.S. Steel Košice. '
article_number: '180508'
article_processing_charge: No
article_type: original
author:
- first_name: Martin
full_name: Zemlicka, Martin
id: 2DCF8DE6-F248-11E8-B48F-1D18A9856A87
last_name: Zemlicka
- first_name: M.
full_name: Kopčík, M.
last_name: Kopčík
- first_name: P.
full_name: Szabó, P.
last_name: Szabó
- first_name: T.
full_name: Samuely, T.
last_name: Samuely
- first_name: J.
full_name: Kačmarčík, J.
last_name: Kačmarčík
- first_name: P.
full_name: Neilinger, P.
last_name: Neilinger
- first_name: M.
full_name: Grajcar, M.
last_name: Grajcar
- first_name: P.
full_name: Samuely, P.
last_name: Samuely
citation:
ama: 'Zemlicka M, Kopčík M, Szabó P, et al. Zeeman-driven superconductor-insulator
transition in strongly disordered MoC films: Scanning tunneling microscopy and
transport studies in a transverse magnetic field. Physical Review B. 2020;102(18).
doi:10.1103/PhysRevB.102.180508'
apa: 'Zemlicka, M., Kopčík, M., Szabó, P., Samuely, T., Kačmarčík, J., Neilinger,
P., … Samuely, P. (2020). Zeeman-driven superconductor-insulator transition in
strongly disordered MoC films: Scanning tunneling microscopy and transport studies
in a transverse magnetic field. Physical Review B. American Physical Society.
https://doi.org/10.1103/PhysRevB.102.180508'
chicago: 'Zemlicka, Martin, M. Kopčík, P. Szabó, T. Samuely, J. Kačmarčík, P. Neilinger,
M. Grajcar, and P. Samuely. “Zeeman-Driven Superconductor-Insulator Transition
in Strongly Disordered MoC Films: Scanning Tunneling Microscopy and Transport
Studies in a Transverse Magnetic Field.” Physical Review B. American Physical
Society, 2020. https://doi.org/10.1103/PhysRevB.102.180508.'
ieee: 'M. Zemlicka et al., “Zeeman-driven superconductor-insulator transition
in strongly disordered MoC films: Scanning tunneling microscopy and transport
studies in a transverse magnetic field,” Physical Review B, vol. 102, no.
18. American Physical Society, 2020.'
ista: 'Zemlicka M, Kopčík M, Szabó P, Samuely T, Kačmarčík J, Neilinger P, Grajcar
M, Samuely P. 2020. Zeeman-driven superconductor-insulator transition in strongly
disordered MoC films: Scanning tunneling microscopy and transport studies in a
transverse magnetic field. Physical Review B. 102(18), 180508.'
mla: 'Zemlicka, Martin, et al. “Zeeman-Driven Superconductor-Insulator Transition
in Strongly Disordered MoC Films: Scanning Tunneling Microscopy and Transport
Studies in a Transverse Magnetic Field.” Physical Review B, vol. 102, no.
18, 180508, American Physical Society, 2020, doi:10.1103/PhysRevB.102.180508.'
short: M. Zemlicka, M. Kopčík, P. Szabó, T. Samuely, J. Kačmarčík, P. Neilinger,
M. Grajcar, P. Samuely, Physical Review B 102 (2020).
date_created: 2020-12-13T23:01:21Z
date_published: 2020-11-01T00:00:00Z
date_updated: 2023-08-24T10:53:36Z
day: '01'
department:
- _id: JoFi
doi: 10.1103/PhysRevB.102.180508
external_id:
arxiv:
- '2011.04329'
isi:
- '000591509900003'
intvolume: ' 102'
isi: 1
issue: '18'
language:
- iso: eng
main_file_link:
- open_access: '1'
url: https://arxiv.org/abs/2011.04329
month: '11'
oa: 1
oa_version: Preprint
publication: Physical Review B
publication_identifier:
eissn:
- '24699969'
issn:
- '24699950'
publication_status: published
publisher: American Physical Society
quality_controlled: '1'
scopus_import: '1'
status: public
title: 'Zeeman-driven superconductor-insulator transition in strongly disordered MoC
films: Scanning tunneling microscopy and transport studies in a transverse magnetic
field'
type: journal_article
user_id: 4359f0d1-fa6c-11eb-b949-802e58b17ae8
volume: 102
year: '2020'
...
---
_id: '8955'
abstract:
- lang: eng
text: Skeletal muscle activity is continuously modulated across physiologic states
to provide coordination, flexibility and responsiveness to body tasks and external
inputs. Despite the central role the muscular system plays in facilitating vital
body functions, the network of brain-muscle interactions required to control hundreds
of muscles and synchronize their activation in relation to distinct physiologic
states has not been investigated. Recent approaches have focused on general associations
between individual brain rhythms and muscle activation during movement tasks.
However, the specific forms of coupling, the functional network of cortico-muscular
coordination, and how network structure and dynamics are modulated by autonomic
regulation across physiologic states remains unknown. To identify and quantify
the cortico-muscular interaction network and uncover basic features of neuro-autonomic
control of muscle function, we investigate the coupling between synchronous bursts
in cortical rhythms and peripheral muscle activation during sleep and wake. Utilizing
the concept of time delay stability and a novel network physiology approach, we
find that the brain-muscle network exhibits complex dynamic patterns of communication
involving multiple brain rhythms across cortical locations and different electromyographic
frequency bands. Moreover, our results show that during each physiologic state
the cortico-muscular network is characterized by a specific profile of network
links strength, where particular brain rhythms play role of main mediators of
interaction and control. Further, we discover a hierarchical reorganization in
network structure across physiologic states, with high connectivity and network
link strength during wake, intermediate during REM and light sleep, and low during
deep sleep, a sleep-stage stratification that demonstrates a unique association
between physiologic states and cortico-muscular network structure. The reported
empirical observations are consistent across individual subjects, indicating universal
behavior in network structure and dynamics, and high sensitivity of cortico-muscular
control to changes in autonomic regulation, even at low levels of physical activity
and muscle tone during sleep. Our findings demonstrate previously unrecognized
basic principles of brain-muscle network communication and control, and provide
new perspectives on the regulatory mechanisms of brain dynamics and locomotor
activation, with potential clinical implications for neurodegenerative, movement
and sleep disorders, and for developing efficient treatment strategies.
acknowledgement: We acknowledge support from the W. M. Keck Foundation, National Institutes
of Health (NIH Grant 1R01-HL098437), the US-Israel Binational Science Foundation
(BSF Grant 2012219), and the Office of Naval Research (ONR Grant 000141010078).
FL acknowledges support also from the European Union's Horizon 2020 research and
innovation program under the Marie Sklodowska-Curie Grant Agreement No. 754411.
article_number: '558070'
article_processing_charge: No
article_type: original
author:
- first_name: Rossella
full_name: Rizzo, Rossella
last_name: Rizzo
- first_name: Xiyun
full_name: Zhang, Xiyun
last_name: Zhang
- first_name: Jilin W.J.L.
full_name: Wang, Jilin W.J.L.
last_name: Wang
- first_name: Fabrizio
full_name: Lombardi, Fabrizio
id: A057D288-3E88-11E9-986D-0CF4E5697425
last_name: Lombardi
orcid: 0000-0003-2623-5249
- first_name: Plamen Ch
full_name: Ivanov, Plamen Ch
last_name: Ivanov
citation:
ama: Rizzo R, Zhang X, Wang JWJL, Lombardi F, Ivanov PC. Network physiology of cortico–muscular
interactions. Frontiers in Physiology. 2020;11. doi:10.3389/fphys.2020.558070
apa: Rizzo, R., Zhang, X., Wang, J. W. J. L., Lombardi, F., & Ivanov, P. C.
(2020). Network physiology of cortico–muscular interactions. Frontiers in Physiology.
Frontiers. https://doi.org/10.3389/fphys.2020.558070
chicago: Rizzo, Rossella, Xiyun Zhang, Jilin W.J.L. Wang, Fabrizio Lombardi, and
Plamen Ch Ivanov. “Network Physiology of Cortico–Muscular Interactions.” Frontiers
in Physiology. Frontiers, 2020. https://doi.org/10.3389/fphys.2020.558070.
ieee: R. Rizzo, X. Zhang, J. W. J. L. Wang, F. Lombardi, and P. C. Ivanov, “Network
physiology of cortico–muscular interactions,” Frontiers in Physiology,
vol. 11. Frontiers, 2020.
ista: Rizzo R, Zhang X, Wang JWJL, Lombardi F, Ivanov PC. 2020. Network physiology
of cortico–muscular interactions. Frontiers in Physiology. 11, 558070.
mla: Rizzo, Rossella, et al. “Network Physiology of Cortico–Muscular Interactions.”
Frontiers in Physiology, vol. 11, 558070, Frontiers, 2020, doi:10.3389/fphys.2020.558070.
short: R. Rizzo, X. Zhang, J.W.J.L. Wang, F. Lombardi, P.C. Ivanov, Frontiers in
Physiology 11 (2020).
date_created: 2020-12-20T23:01:18Z
date_published: 2020-11-26T00:00:00Z
date_updated: 2023-08-24T11:00:45Z
day: '26'
ddc:
- '570'
department:
- _id: GaTk
doi: 10.3389/fphys.2020.558070
ec_funded: 1
external_id:
isi:
- '000596849400001'
pmid:
- '33324233'
file:
- access_level: open_access
checksum: ef9515b28c5619b7126c0f347958bcb3
content_type: application/pdf
creator: dernst
date_created: 2020-12-21T10:37:50Z
date_updated: 2020-12-21T10:37:50Z
file_id: '8961'
file_name: 2020_Frontiers_Rizzo.pdf
file_size: 13380030
relation: main_file
success: 1
file_date_updated: 2020-12-21T10:37:50Z
has_accepted_license: '1'
intvolume: ' 11'
isi: 1
language:
- iso: eng
month: '11'
oa: 1
oa_version: Published Version
pmid: 1
project:
- _id: 260C2330-B435-11E9-9278-68D0E5697425
call_identifier: H2020
grant_number: '754411'
name: ISTplus - Postdoctoral Fellowships
publication: Frontiers in Physiology
publication_identifier:
eissn:
- 1664042X
publication_status: published
publisher: Frontiers
quality_controlled: '1'
scopus_import: '1'
status: public
title: Network physiology of cortico–muscular interactions
tmp:
image: /images/cc_by.png
legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
short: CC BY (4.0)
type: journal_article
user_id: 4359f0d1-fa6c-11eb-b949-802e58b17ae8
volume: 11
year: '2020'
...
---
_id: '8949'
abstract:
- lang: eng
text: Development of the nervous system undergoes important transitions,
including one from neurogenesis to gliogenesis which occurs late during embryonic
gestation. Here we report on clonal analysis of gliogenesis in mice using Mosaic
Analysis with Double Markers (MADM) with quantitative and computational methods.
Results reveal that developmental gliogenesis in the cerebral cortex occurs in
a fraction of earlier neurogenic clones, accelerating around E16.5, and giving
rise to both astrocytes and oligodendrocytes. Moreover, MADM-based genetic deletion
of the epidermal growth factor receptor (Egfr) in gliogenic clones revealed that
Egfr is cell autonomously required for gliogenesis in the mouse dorsolateral cortices.
A broad range in the proliferation capacity, symmetry of clones, and competitive
advantage of MADM cells was evident in clones that contained one cellular lineage
with double dosage of Egfr relative to their environment, while their sibling
Egfr-null cells failed to generate glia. Remarkably, the total numbers of glia
in MADM clones balance out regardless of significant alterations in clonal symmetries.
The variability in glial clones shows stochastic patterns that we define mathematically,
which are different from the deterministic patterns in neuronal clones. This study
sets a foundation for studying the biological significance of stochastic and deterministic
clonal principles underlying tissue development, and identifying mechanisms that
differentiate between neurogenesis and gliogenesis.
acknowledgement: This research was funded by grants from the National Institutes of
Health to H.T.G. (R01NS098370 and R01NS089795). C.V.M. was supported by a National
Science Foundation Graduate Research Fellowship (DGE-1746939). R.B. was supported
by the FWF Lise-Meitner program (M 2416), and S.H. was supported by the European
Research Council (ERC) under the European Union’s Horizon 2020 research and innovation
programme (grant agreement No 725780 LinPro).The authors thank members of the Ghashghaei
lab for discussions, technical support, and help with preparation of the manuscript.
article_number: '2662'
article_processing_charge: No
article_type: original
author:
- first_name: Xuying
full_name: Zhang, Xuying
last_name: Zhang
- first_name: Christine V.
full_name: Mennicke, Christine V.
last_name: Mennicke
- first_name: Guanxi
full_name: Xiao, Guanxi
last_name: Xiao
- first_name: Robert J
full_name: Beattie, Robert J
id: 2E26DF60-F248-11E8-B48F-1D18A9856A87
last_name: Beattie
orcid: 0000-0002-8483-8753
- first_name: Mansoor
full_name: Haider, Mansoor
last_name: Haider
- first_name: Simon
full_name: Hippenmeyer, Simon
id: 37B36620-F248-11E8-B48F-1D18A9856A87
last_name: Hippenmeyer
orcid: 0000-0003-2279-1061
- first_name: H. Troy
full_name: Ghashghaei, H. Troy
last_name: Ghashghaei
citation:
ama: Zhang X, Mennicke CV, Xiao G, et al. Clonal analysis of gliogenesis in the
cerebral cortex reveals stochastic expansion of glia and cell autonomous responses
to Egfr dosage. Cells. 2020;9(12). doi:10.3390/cells9122662
apa: Zhang, X., Mennicke, C. V., Xiao, G., Beattie, R. J., Haider, M., Hippenmeyer,
S., & Ghashghaei, H. T. (2020). Clonal analysis of gliogenesis in the cerebral
cortex reveals stochastic expansion of glia and cell autonomous responses to Egfr
dosage. Cells. MDPI. https://doi.org/10.3390/cells9122662
chicago: Zhang, Xuying, Christine V. Mennicke, Guanxi Xiao, Robert J Beattie, Mansoor
Haider, Simon Hippenmeyer, and H. Troy Ghashghaei. “Clonal Analysis of Gliogenesis
in the Cerebral Cortex Reveals Stochastic Expansion of Glia and Cell Autonomous
Responses to Egfr Dosage.” Cells. MDPI, 2020. https://doi.org/10.3390/cells9122662.
ieee: X. Zhang et al., “Clonal analysis of gliogenesis in the cerebral cortex
reveals stochastic expansion of glia and cell autonomous responses to Egfr dosage,”
Cells, vol. 9, no. 12. MDPI, 2020.
ista: Zhang X, Mennicke CV, Xiao G, Beattie RJ, Haider M, Hippenmeyer S, Ghashghaei
HT. 2020. Clonal analysis of gliogenesis in the cerebral cortex reveals stochastic
expansion of glia and cell autonomous responses to Egfr dosage. Cells. 9(12),
2662.
mla: Zhang, Xuying, et al. “Clonal Analysis of Gliogenesis in the Cerebral Cortex
Reveals Stochastic Expansion of Glia and Cell Autonomous Responses to Egfr Dosage.”
Cells, vol. 9, no. 12, 2662, MDPI, 2020, doi:10.3390/cells9122662.
short: X. Zhang, C.V. Mennicke, G. Xiao, R.J. Beattie, M. Haider, S. Hippenmeyer,
H.T. Ghashghaei, Cells 9 (2020).
date_created: 2020-12-14T08:04:03Z
date_published: 2020-12-11T00:00:00Z
date_updated: 2023-08-24T10:57:48Z
day: '11'
ddc:
- '570'
department:
- _id: SiHi
doi: 10.3390/cells9122662
ec_funded: 1
external_id:
isi:
- '000601787300001'
file:
- access_level: open_access
checksum: 5095cbdc728c9a510c5761cf60a8861c
content_type: application/pdf
creator: dernst
date_created: 2020-12-14T08:09:43Z
date_updated: 2020-12-14T08:09:43Z
file_id: '8950'
file_name: 2020_Cells_Zhang.pdf
file_size: 3504525
relation: main_file
success: 1
file_date_updated: 2020-12-14T08:09:43Z
has_accepted_license: '1'
intvolume: ' 9'
isi: 1
issue: '12'
language:
- iso: eng
month: '12'
oa: 1
oa_version: Published Version
project:
- _id: 264E56E2-B435-11E9-9278-68D0E5697425
call_identifier: FWF
grant_number: M02416
name: Molecular Mechanisms Regulating Gliogenesis in the Cerebral Cortex
- _id: 260018B0-B435-11E9-9278-68D0E5697425
call_identifier: H2020
grant_number: '725780'
name: Principles of Neural Stem Cell Lineage Progression in Cerebral Cortex Development
publication: Cells
publication_identifier:
issn:
- 2073-4409
publication_status: published
publisher: MDPI
quality_controlled: '1'
status: public
title: Clonal analysis of gliogenesis in the cerebral cortex reveals stochastic expansion
of glia and cell autonomous responses to Egfr dosage
tmp:
image: /images/cc_by.png
legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
short: CC BY (4.0)
type: journal_article
user_id: 4359f0d1-fa6c-11eb-b949-802e58b17ae8
volume: 9
year: '2020'
...
---
_id: '8971'
abstract:
- lang: eng
text: The actin-related protein (Arp)2/3 complex nucleates branched actin filament
networks pivotal for cell migration, endocytosis and pathogen infection. Its activation
is tightly regulated and involves complex structural rearrangements and actin
filament binding, which are yet to be understood. Here, we report a 9.0 Å resolution
structure of the actin filament Arp2/3 complex branch junction in cells using
cryo-electron tomography and subtomogram averaging. This allows us to generate
an accurate model of the active Arp2/3 complex in the branch junction and its
interaction with actin filaments. Notably, our model reveals a previously undescribed
set of interactions of the Arp2/3 complex with the mother filament, significantly
different to the previous branch junction model. Our structure also indicates
a central role for the ArpC3 subunit in stabilizing the active conformation.
acknowledged_ssus:
- _id: ScienComp
- _id: LifeSc
- _id: Bio
- _id: EM-Fac
acknowledgement: "This research was supported by the Scientific Service Units (SSUs)
of IST Austria through resources provided by Scientific Computing (SciComp), the
Life Science Facility (LSF), the BioImaging Facility (BIF), and the Electron Microscopy
Facility (EMF). We also thank Dimitry Tegunov (MPI for Biophysical Chemistry) for
helpful discussions\r\nabout the M software, and Michael Sixt (IST Austria) and
Klemens Rottner (Technical University Braunschweig, HZI Braunschweig) for critical
reading of the manuscript. We also thank Gregory Voth (University of Chicago) for
providing us the MD-derived branch junction model for comparison. The authors acknowledge
support from IST Austria and from the Austrian Science Fund (FWF): M02495 to G.D.
and Austrian Science Fund (FWF): P33367 to F.K.M.S. "
article_number: '6437'
article_processing_charge: No
article_type: original
author:
- first_name: Florian
full_name: Fäßler, Florian
id: 404F5528-F248-11E8-B48F-1D18A9856A87
last_name: Fäßler
orcid: 0000-0001-7149-769X
- first_name: Georgi A
full_name: Dimchev, Georgi A
id: 38C393BE-F248-11E8-B48F-1D18A9856A87
last_name: Dimchev
orcid: 0000-0001-8370-6161
- first_name: Victor-Valentin
full_name: Hodirnau, Victor-Valentin
id: 3661B498-F248-11E8-B48F-1D18A9856A87
last_name: Hodirnau
- first_name: William
full_name: Wan, William
last_name: Wan
- first_name: Florian KM
full_name: Schur, Florian KM
id: 48AD8942-F248-11E8-B48F-1D18A9856A87
last_name: Schur
orcid: 0000-0003-4790-8078
citation:
ama: Fäßler F, Dimchev GA, Hodirnau V-V, Wan W, Schur FK. Cryo-electron tomography
structure of Arp2/3 complex in cells reveals new insights into the branch junction.
Nature Communications. 2020;11. doi:10.1038/s41467-020-20286-x
apa: Fäßler, F., Dimchev, G. A., Hodirnau, V.-V., Wan, W., & Schur, F. K. (2020).
Cryo-electron tomography structure of Arp2/3 complex in cells reveals new insights
into the branch junction. Nature Communications. Springer Nature. https://doi.org/10.1038/s41467-020-20286-x
chicago: Fäßler, Florian, Georgi A Dimchev, Victor-Valentin Hodirnau, William Wan,
and Florian KM Schur. “Cryo-Electron Tomography Structure of Arp2/3 Complex in
Cells Reveals New Insights into the Branch Junction.” Nature Communications.
Springer Nature, 2020. https://doi.org/10.1038/s41467-020-20286-x.
ieee: F. Fäßler, G. A. Dimchev, V.-V. Hodirnau, W. Wan, and F. K. Schur, “Cryo-electron
tomography structure of Arp2/3 complex in cells reveals new insights into the
branch junction,” Nature Communications, vol. 11. Springer Nature, 2020.
ista: Fäßler F, Dimchev GA, Hodirnau V-V, Wan W, Schur FK. 2020. Cryo-electron tomography
structure of Arp2/3 complex in cells reveals new insights into the branch junction.
Nature Communications. 11, 6437.
mla: Fäßler, Florian, et al. “Cryo-Electron Tomography Structure of Arp2/3 Complex
in Cells Reveals New Insights into the Branch Junction.” Nature Communications,
vol. 11, 6437, Springer Nature, 2020, doi:10.1038/s41467-020-20286-x.
short: F. Fäßler, G.A. Dimchev, V.-V. Hodirnau, W. Wan, F.K. Schur, Nature Communications
11 (2020).
date_created: 2020-12-23T08:25:45Z
date_published: 2020-12-22T00:00:00Z
date_updated: 2023-08-24T11:01:50Z
day: '22'
ddc:
- '570'
department:
- _id: FlSc
- _id: EM-Fac
doi: 10.1038/s41467-020-20286-x
external_id:
isi:
- '000603078000003'
file:
- access_level: open_access
checksum: 55d43ea0061cc4027ba45e966e1db8cc
content_type: application/pdf
creator: dernst
date_created: 2020-12-28T08:16:10Z
date_updated: 2020-12-28T08:16:10Z
file_id: '8975'
file_name: 2020_NatureComm_Faessler.pdf
file_size: 3958727
relation: main_file
success: 1
file_date_updated: 2020-12-28T08:16:10Z
has_accepted_license: '1'
intvolume: ' 11'
isi: 1
keyword:
- General Biochemistry
- Genetics and Molecular Biology
- General Physics and Astronomy
- General Chemistry
language:
- iso: eng
month: '12'
oa: 1
oa_version: Published Version
project:
- _id: 9B954C5C-BA93-11EA-9121-9846C619BF3A
grant_number: P33367
name: Structure and isoform diversity of the Arp2/3 complex
- _id: 2674F658-B435-11E9-9278-68D0E5697425
call_identifier: FWF
grant_number: M02495
name: Protein structure and function in filopodia across scales
publication: Nature Communications
publication_identifier:
issn:
- 2041-1723
publication_status: published
publisher: Springer Nature
quality_controlled: '1'
related_material:
link:
- description: News on IST Homepage
relation: press_release
url: https://ist.ac.at/en/news/cutting-edge-technology-reveals-structures-within-cells/
scopus_import: '1'
status: public
title: Cryo-electron tomography structure of Arp2/3 complex in cells reveals new insights
into the branch junction
tmp:
image: /images/cc_by.png
legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
short: CC BY (4.0)
type: journal_article
user_id: 4359f0d1-fa6c-11eb-b949-802e58b17ae8
volume: 11
year: '2020'
...
---
_id: '8987'
abstract:
- lang: eng
text: "Currently several projects aim at designing and implementing protocols for
privacy preserving automated contact tracing to help fight the current pandemic.
Those proposal are quite similar, and in their most basic form basically propose
an app for mobile phones which broadcasts frequently changing pseudorandom identifiers
via (low energy) Bluetooth, and at the same time, the app stores IDs broadcast
by phones in its proximity. Only if a user is tested positive, they upload either
the beacons they did broadcast (which is the case in decentralized proposals as
DP-3T, east and west coast PACT or Covid watch) or received (as in Popp-PT or
ROBERT) during the last two weeks or so.\r\n\r\nVaudenay [eprint 2020/399] observes
that this basic scheme (he considers the DP-3T proposal) succumbs to relay and
even replay attacks, and proposes more complex interactive schemes which prevent
those attacks without giving up too many privacy aspects. Unfortunately interaction
is problematic for this application for efficiency and security reasons. The countermeasures
that have been suggested so far are either not practical or give up on key privacy
aspects. We propose a simple non-interactive variant of the basic protocol that\r\n(security)
Provably prevents replay and (if location data is available) relay attacks.\r\n(privacy)
The data of all parties (even jointly) reveals no information on the location
or time where encounters happened.\r\n(efficiency) The broadcasted message can
fit into 128 bits and uses only basic crypto (commitments and secret key authentication).\r\n\r\nTowards
this end we introduce the concept of “delayed authentication”, which basically
is a message authentication code where verification can be done in two steps,
where the first doesn’t require the key, and the second doesn’t require the message."
article_processing_charge: No
author:
- first_name: Krzysztof Z
full_name: Pietrzak, Krzysztof Z
id: 3E04A7AA-F248-11E8-B48F-1D18A9856A87
last_name: Pietrzak
orcid: 0000-0002-9139-1654
citation:
ama: 'Pietrzak KZ. Delayed authentication: Preventing replay and relay attacks in
private contact tracing. In: Progress in Cryptology. Vol 12578. LNCS. Springer
Nature; 2020:3-15. doi:10.1007/978-3-030-65277-7_1'
apa: 'Pietrzak, K. Z. (2020). Delayed authentication: Preventing replay and relay
attacks in private contact tracing. In Progress in Cryptology (Vol. 12578,
pp. 3–15). Bangalore, India: Springer Nature. https://doi.org/10.1007/978-3-030-65277-7_1'
chicago: 'Pietrzak, Krzysztof Z. “Delayed Authentication: Preventing Replay and
Relay Attacks in Private Contact Tracing.” In Progress in Cryptology, 12578:3–15.
LNCS. Springer Nature, 2020. https://doi.org/10.1007/978-3-030-65277-7_1.'
ieee: 'K. Z. Pietrzak, “Delayed authentication: Preventing replay and relay attacks
in private contact tracing,” in Progress in Cryptology, Bangalore, India,
2020, vol. 12578, pp. 3–15.'
ista: 'Pietrzak KZ. 2020. Delayed authentication: Preventing replay and relay attacks
in private contact tracing. Progress in Cryptology. INDOCRYPT: International Conference
on Cryptology in IndiaLNCS vol. 12578, 3–15.'
mla: 'Pietrzak, Krzysztof Z. “Delayed Authentication: Preventing Replay and Relay
Attacks in Private Contact Tracing.” Progress in Cryptology, vol. 12578,
Springer Nature, 2020, pp. 3–15, doi:10.1007/978-3-030-65277-7_1.'
short: K.Z. Pietrzak, in:, Progress in Cryptology, Springer Nature, 2020, pp. 3–15.
conference:
end_date: 2020-12-16
location: Bangalore, India
name: 'INDOCRYPT: International Conference on Cryptology in India'
start_date: 2020-12-13
date_created: 2021-01-03T23:01:23Z
date_published: 2020-12-08T00:00:00Z
date_updated: 2023-08-24T11:08:58Z
day: '08'
department:
- _id: KrPi
doi: 10.1007/978-3-030-65277-7_1
ec_funded: 1
external_id:
isi:
- '000927592800001'
intvolume: ' 12578'
isi: 1
language:
- iso: eng
main_file_link:
- open_access: '1'
url: https://eprint.iacr.org/2020/418
month: '12'
oa: 1
oa_version: Preprint
page: 3-15
project:
- _id: 258AA5B2-B435-11E9-9278-68D0E5697425
call_identifier: H2020
grant_number: '682815'
name: Teaching Old Crypto New Tricks
publication: Progress in Cryptology
publication_identifier:
eissn:
- '16113349'
isbn:
- '9783030652760'
issn:
- '03029743'
publication_status: published
publisher: Springer Nature
quality_controlled: '1'
scopus_import: '1'
series_title: LNCS
status: public
title: 'Delayed authentication: Preventing replay and relay attacks in private contact
tracing'
type: conference
user_id: 4359f0d1-fa6c-11eb-b949-802e58b17ae8
volume: 12578
year: '2020'
...
---
_id: '8957'
abstract:
- lang: eng
text: Global tissue tension anisotropy has been shown to trigger stereotypical cell
division orientation by elongating mitotic cells along the main tension axis.
Yet, how tissue tension elongates mitotic cells despite those cells undergoing
mitotic rounding (MR) by globally upregulating cortical actomyosin tension remains
unclear. We addressed this question by taking advantage of ascidian embryos, consisting
of a small number of interphasic and mitotic blastomeres and displaying an invariant
division pattern. We found that blastomeres undergo MR by locally relaxing cortical
tension at their apex, thereby allowing extrinsic pulling forces from neighboring
interphasic blastomeres to polarize their shape and thus division orientation.
Consistently, interfering with extrinsic forces by reducing the contractility
of interphasic blastomeres or disrupting the establishment of asynchronous mitotic
domains leads to aberrant mitotic cell division orientations. Thus, apical relaxation
during MR constitutes a key mechanism by which tissue tension anisotropy controls
stereotypical cell division orientation.
acknowledged_ssus:
- _id: Bio
- _id: NanoFab
acknowledgement: 'We thank members of the Heisenberg and McDougall groups for technical
advice and discussion, Hitoyoshi Yasuo for sharing lab equipment, Lucas Leclère
and Hitoyoshi Yasuo for their comments on a preliminary version of the manuscript,
and Philippe Dru for the Rose plots. We are grateful to the Bioimaging and Nanofabrication
facilities of IST Austria and the Imaging Platform (PIM) and animal facility (CRB)
of Institut de la Mer de Villefranche (IMEV), which is supported by EMBRC-France,
whose French state funds are managed by the ANR within the Investments of the Future
program under reference ANR-10-INBS-0, for continuous support. This work was supported
by a grant from the French Government funding agency Agence National de la Recherche
(ANR “MorCell”: ANR-17-CE 13-002 8).'
article_processing_charge: No
article_type: original
author:
- first_name: Benoit G
full_name: Godard, Benoit G
id: 33280250-F248-11E8-B48F-1D18A9856A87
last_name: Godard
- first_name: Rémi
full_name: Dumollard, Rémi
last_name: Dumollard
- first_name: Edwin
full_name: Munro, Edwin
last_name: Munro
- first_name: Janet
full_name: Chenevert, Janet
last_name: Chenevert
- first_name: Céline
full_name: Hebras, Céline
last_name: Hebras
- first_name: Alex
full_name: Mcdougall, Alex
last_name: Mcdougall
- first_name: Carl-Philipp J
full_name: Heisenberg, Carl-Philipp J
id: 39427864-F248-11E8-B48F-1D18A9856A87
last_name: Heisenberg
orcid: 0000-0002-0912-4566
citation:
ama: Godard BG, Dumollard R, Munro E, et al. Apical relaxation during mitotic rounding
promotes tension-oriented cell division. Developmental Cell. 2020;55(6):695-706.
doi:10.1016/j.devcel.2020.10.016
apa: Godard, B. G., Dumollard, R., Munro, E., Chenevert, J., Hebras, C., Mcdougall,
A., & Heisenberg, C.-P. J. (2020). Apical relaxation during mitotic rounding
promotes tension-oriented cell division. Developmental Cell. Elsevier.
https://doi.org/10.1016/j.devcel.2020.10.016
chicago: Godard, Benoit G, Rémi Dumollard, Edwin Munro, Janet Chenevert, Céline
Hebras, Alex Mcdougall, and Carl-Philipp J Heisenberg. “Apical Relaxation during
Mitotic Rounding Promotes Tension-Oriented Cell Division.” Developmental Cell.
Elsevier, 2020. https://doi.org/10.1016/j.devcel.2020.10.016.
ieee: B. G. Godard et al., “Apical relaxation during mitotic rounding promotes
tension-oriented cell division,” Developmental Cell, vol. 55, no. 6. Elsevier,
pp. 695–706, 2020.
ista: Godard BG, Dumollard R, Munro E, Chenevert J, Hebras C, Mcdougall A, Heisenberg
C-PJ. 2020. Apical relaxation during mitotic rounding promotes tension-oriented
cell division. Developmental Cell. 55(6), 695–706.
mla: Godard, Benoit G., et al. “Apical Relaxation during Mitotic Rounding Promotes
Tension-Oriented Cell Division.” Developmental Cell, vol. 55, no. 6, Elsevier,
2020, pp. 695–706, doi:10.1016/j.devcel.2020.10.016.
short: B.G. Godard, R. Dumollard, E. Munro, J. Chenevert, C. Hebras, A. Mcdougall,
C.-P.J. Heisenberg, Developmental Cell 55 (2020) 695–706.
date_created: 2020-12-20T23:01:19Z
date_published: 2020-12-21T00:00:00Z
date_updated: 2023-08-24T11:01:22Z
day: '21'
department:
- _id: CaHe
doi: 10.1016/j.devcel.2020.10.016
external_id:
isi:
- '000600665700008'
pmid:
- '33207225'
intvolume: ' 55'
isi: 1
issue: '6'
language:
- iso: eng
month: '12'
oa_version: None
page: 695-706
pmid: 1
publication: Developmental Cell
publication_identifier:
eissn:
- '18781551'
issn:
- '15345807'
publication_status: published
publisher: Elsevier
quality_controlled: '1'
related_material:
link:
- description: News on IST Homepage
relation: press_release
url: https://ist.ac.at/en/news/relaxing-cell-divisions/
scopus_import: '1'
status: public
title: Apical relaxation during mitotic rounding promotes tension-oriented cell division
type: journal_article
user_id: 4359f0d1-fa6c-11eb-b949-802e58b17ae8
volume: 55
year: '2020'
...
---
_id: '9000'
abstract:
- lang: eng
text: 'In prokaryotes, thermodynamic models of gene regulation provide a highly
quantitative mapping from promoter sequences to gene-expression levels that is
compatible with in vivo and in vitro biophysical measurements. Such concordance
has not been achieved for models of enhancer function in eukaryotes. In equilibrium
models, it is difficult to reconcile the reported short transcription factor (TF)
residence times on the DNA with the high specificity of regulation. In nonequilibrium
models, progress is difficult due to an explosion in the number of parameters.
Here, we navigate this complexity by looking for minimal nonequilibrium enhancer
models that yield desired regulatory phenotypes: low TF residence time, high specificity,
and tunable cooperativity. We find that a single extra parameter, interpretable
as the “linking rate,” by which bound TFs interact with Mediator components, enables
our models to escape equilibrium bounds and access optimal regulatory phenotypes,
while remaining consistent with the reported phenomenology and simple enough to
be inferred from upcoming experiments. We further find that high specificity in
nonequilibrium models is in a trade-off with gene-expression noise, predicting
bursty dynamics—an experimentally observed hallmark of eukaryotic transcription.
By drastically reducing the vast parameter space of nonequilibrium enhancer models
to a much smaller subspace that optimally realizes biological function, we deliver
a rich class of models that could be tractably inferred from data in the near
future.'
acknowledgement: G.T. was supported by Human Frontiers Science Program Grant RGP0034/2018.
R.G. was supported by the Austrian Academy of Sciences DOC Fellowship. R.G. thanks
S. Avvakumov for helpful discussions.
article_processing_charge: No
article_type: original
author:
- first_name: Rok
full_name: Grah, Rok
id: 483E70DE-F248-11E8-B48F-1D18A9856A87
last_name: Grah
orcid: 0000-0003-2539-3560
- first_name: Benjamin
full_name: Zoller, Benjamin
last_name: Zoller
- first_name: Gašper
full_name: Tkačik, Gašper
id: 3D494DCA-F248-11E8-B48F-1D18A9856A87
last_name: Tkačik
orcid: 0000-0002-6699-1455
citation:
ama: Grah R, Zoller B, Tkačik G. Nonequilibrium models of optimal enhancer function.
PNAS. 2020;117(50):31614-31622. doi:10.1073/pnas.2006731117
apa: Grah, R., Zoller, B., & Tkačik, G. (2020). Nonequilibrium models of optimal
enhancer function. PNAS. National Academy of Sciences. https://doi.org/10.1073/pnas.2006731117
chicago: Grah, Rok, Benjamin Zoller, and Gašper Tkačik. “Nonequilibrium Models of
Optimal Enhancer Function.” PNAS. National Academy of Sciences, 2020. https://doi.org/10.1073/pnas.2006731117.
ieee: R. Grah, B. Zoller, and G. Tkačik, “Nonequilibrium models of optimal enhancer
function,” PNAS, vol. 117, no. 50. National Academy of Sciences, pp. 31614–31622,
2020.
ista: Grah R, Zoller B, Tkačik G. 2020. Nonequilibrium models of optimal enhancer
function. PNAS. 117(50), 31614–31622.
mla: Grah, Rok, et al. “Nonequilibrium Models of Optimal Enhancer Function.” PNAS,
vol. 117, no. 50, National Academy of Sciences, 2020, pp. 31614–22, doi:10.1073/pnas.2006731117.
short: R. Grah, B. Zoller, G. Tkačik, PNAS 117 (2020) 31614–31622.
date_created: 2021-01-10T23:01:17Z
date_published: 2020-12-15T00:00:00Z
date_updated: 2023-08-24T11:10:22Z
day: '15'
ddc:
- '570'
department:
- _id: GaTk
doi: 10.1073/pnas.2006731117
external_id:
isi:
- '000600608300015'
pmid:
- '33268497'
file:
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checksum: 69039cd402a571983aa6cb4815ffa863
content_type: application/pdf
creator: dernst
date_created: 2021-01-11T08:37:31Z
date_updated: 2021-01-11T08:37:31Z
file_id: '9004'
file_name: 2020_PNAS_Grah.pdf
file_size: 1199247
relation: main_file
success: 1
file_date_updated: 2021-01-11T08:37:31Z
has_accepted_license: '1'
intvolume: ' 117'
isi: 1
issue: '50'
language:
- iso: eng
month: '12'
oa: 1
oa_version: Published Version
page: 31614-31622
pmid: 1
project:
- _id: 2665AAFE-B435-11E9-9278-68D0E5697425
grant_number: RGP0034/2018
name: Can evolution minimize spurious signaling crosstalk to reach optimal performance?
- _id: 267C84F4-B435-11E9-9278-68D0E5697425
name: Biophysically realistic genotype-phenotype maps for regulatory networks
publication: PNAS
publication_identifier:
eissn:
- '10916490'
issn:
- '00278424'
publication_status: published
publisher: National Academy of Sciences
quality_controlled: '1'
related_material:
link:
- description: News on IST Homepage
relation: press_release
url: https://ist.ac.at/en/news/new-compact-model-for-gene-regulation-in-higher-organisms/
scopus_import: '1'
status: public
title: Nonequilibrium models of optimal enhancer function
tmp:
image: /images/cc_by_nc_nd.png
legal_code_url: https://creativecommons.org/licenses/by-nc-nd/4.0/legalcode
name: Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International
(CC BY-NC-ND 4.0)
short: CC BY-NC-ND (4.0)
type: journal_article
user_id: 4359f0d1-fa6c-11eb-b949-802e58b17ae8
volume: 117
year: '2020'
...
---
_id: '7910'
abstract:
- lang: eng
text: Quantum illumination uses entangled signal-idler photon pairs to boost the
detection efficiency of low-reflectivity objects in environments with bright thermal
noise. Its advantage is particularly evident at low signal powers, a promising
feature for applications such as noninvasive biomedical scanning or low-power
short-range radar. Here, we experimentally investigate the concept of quantum
illumination at microwave frequencies. We generate entangled fields to illuminate
a room-temperature object at a distance of 1 m in a free-space detection setup.
We implement a digital phase-conjugate receiver based on linear quadrature measurements
that outperforms a symmetric classical noise radar in the same conditions, despite
the entanglement-breaking signal path. Starting from experimental data, we also
simulate the case of perfect idler photon number detection, which results in a
quantum advantage compared with the relative classical benchmark. Our results
highlight the opportunities and challenges in the way toward a first room-temperature
application of microwave quantum circuits.
article_number: eabb0451
article_processing_charge: No
article_type: original
author:
- first_name: Shabir
full_name: Barzanjeh, Shabir
id: 2D25E1F6-F248-11E8-B48F-1D18A9856A87
last_name: Barzanjeh
orcid: 0000-0003-0415-1423
- first_name: S.
full_name: Pirandola, S.
last_name: Pirandola
- first_name: D
full_name: Vitali, D
last_name: Vitali
- first_name: Johannes M
full_name: Fink, Johannes M
id: 4B591CBA-F248-11E8-B48F-1D18A9856A87
last_name: Fink
orcid: 0000-0001-8112-028X
citation:
ama: Barzanjeh S, Pirandola S, Vitali D, Fink JM. Microwave quantum illumination
using a digital receiver. Science Advances. 2020;6(19). doi:10.1126/sciadv.abb0451
apa: Barzanjeh, S., Pirandola, S., Vitali, D., & Fink, J. M. (2020). Microwave
quantum illumination using a digital receiver. Science Advances. AAAS.
https://doi.org/10.1126/sciadv.abb0451
chicago: Barzanjeh, Shabir, S. Pirandola, D Vitali, and Johannes M Fink. “Microwave
Quantum Illumination Using a Digital Receiver.” Science Advances. AAAS,
2020. https://doi.org/10.1126/sciadv.abb0451.
ieee: S. Barzanjeh, S. Pirandola, D. Vitali, and J. M. Fink, “Microwave quantum
illumination using a digital receiver,” Science Advances, vol. 6, no. 19.
AAAS, 2020.
ista: Barzanjeh S, Pirandola S, Vitali D, Fink JM. 2020. Microwave quantum illumination
using a digital receiver. Science Advances. 6(19), eabb0451.
mla: Barzanjeh, Shabir, et al. “Microwave Quantum Illumination Using a Digital Receiver.”
Science Advances, vol. 6, no. 19, eabb0451, AAAS, 2020, doi:10.1126/sciadv.abb0451.
short: S. Barzanjeh, S. Pirandola, D. Vitali, J.M. Fink, Science Advances 6 (2020).
date_created: 2020-05-31T22:00:49Z
date_published: 2020-05-06T00:00:00Z
date_updated: 2023-08-24T11:10:49Z
day: '06'
ddc:
- '530'
department:
- _id: JoFi
doi: 10.1126/sciadv.abb0451
ec_funded: 1
external_id:
arxiv:
- '1908.03058'
isi:
- '000531171100045'
file:
- access_level: open_access
checksum: 16fa61cc1951b444ee74c07188cda9da
content_type: application/pdf
creator: dernst
date_created: 2020-06-02T09:18:36Z
date_updated: 2020-07-14T12:48:05Z
file_id: '7913'
file_name: 2020_ScienceAdvances_Barzanjeh.pdf
file_size: 795822
relation: main_file
file_date_updated: 2020-07-14T12:48:05Z
has_accepted_license: '1'
intvolume: ' 6'
isi: 1
issue: '19'
language:
- iso: eng
month: '05'
oa: 1
oa_version: Published Version
project:
- _id: 26336814-B435-11E9-9278-68D0E5697425
call_identifier: H2020
grant_number: '758053'
name: A Fiber Optic Transceiver for Superconducting Qubits
- _id: 237CBA6C-32DE-11EA-91FC-C7463DDC885E
call_identifier: H2020
grant_number: '862644'
name: Quantum readout techniques and technologies
- _id: 258047B6-B435-11E9-9278-68D0E5697425
call_identifier: H2020
grant_number: '707438'
name: 'Microwave-to-Optical Quantum Link: Quantum Teleportation and Quantum Illumination
with cavity Optomechanics SUPEREOM'
- _id: 257EB838-B435-11E9-9278-68D0E5697425
call_identifier: H2020
grant_number: '732894'
name: Hybrid Optomechanical Technologies
- _id: 26927A52-B435-11E9-9278-68D0E5697425
call_identifier: FWF
grant_number: F07105
name: Integrating superconducting quantum circuits
publication: Science Advances
publication_identifier:
eissn:
- '23752548'
publication_status: published
publisher: AAAS
quality_controlled: '1'
related_material:
link:
- description: News on IST Homepage
relation: press_release
url: https://ist.ac.at/en/news/scientists-demonstrate-quantum-radar-prototype/
record:
- id: '9001'
relation: later_version
status: public
scopus_import: '1'
status: public
title: Microwave quantum illumination using a digital receiver
tmp:
image: /images/cc_by.png
legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
short: CC BY (4.0)
type: journal_article
user_id: 4359f0d1-fa6c-11eb-b949-802e58b17ae8
volume: 6
year: '2020'
...
---
_id: '9001'
abstract:
- lang: eng
text: Quantum illumination is a sensing technique that employs entangled signal-idler
beams to improve the detection efficiency of low-reflectivity objects in environments
with large thermal noise. The advantage over classical strategies is evident at
low signal brightness, a feature which could make the protocol an ideal prototype
for non-invasive scanning or low-power short-range radar. Here we experimentally
investigate the concept of quantum illumination at microwave frequencies, by generating
entangled fields using a Josephson parametric converter which are then amplified
to illuminate a room-temperature object at a distance of 1 meter. Starting from
experimental data, we simulate the case of perfect idler photon number detection,
which results in a quantum advantage compared to the relative classical benchmark.
Our results highlight the opportunities and challenges on the way towards a first
room-temperature application of microwave quantum circuits.
acknowledgement: "This work was supported by the Institute of Science and Technology
Austria (IST Austria), the European Research Council under grant agreement number
758053 (ERC StG QUNNECT) and the EU’s Horizon 2020 research and innovation programme
under grant agreement number 862644 (FET Open QUARTET). S.B. acknowledges support
from the Marie Skłodowska Curie\r\nfellowship number 707438 (MSC-IF SUPEREOM), DV
acknowledge support from EU’s Horizon 2020 research and innovation programme under
grant agreement number 732894 (FET Proactive HOT) and the Project QuaSeRT funded
by the QuantERA ERANET Cofund in Quantum Technologies, and J.M.F from the Austrian
Science Fund (FWF) through BeyondC (F71), a NOMIS foundation research grant, and
the EU’s Horizon 2020 research and\r\ninnovation programme under grant agreement
number 732894 (FET Proactive\r\nHOT)."
article_number: '9266397'
article_processing_charge: No
author:
- first_name: Shabir
full_name: Barzanjeh, Shabir
id: 2D25E1F6-F248-11E8-B48F-1D18A9856A87
last_name: Barzanjeh
orcid: 0000-0003-0415-1423
- first_name: Stefano
full_name: Pirandola, Stefano
last_name: Pirandola
- first_name: David
full_name: Vitali, David
last_name: Vitali
- first_name: Johannes M
full_name: Fink, Johannes M
id: 4B591CBA-F248-11E8-B48F-1D18A9856A87
last_name: Fink
orcid: 0000-0001-8112-028X
citation:
ama: 'Barzanjeh S, Pirandola S, Vitali D, Fink JM. Microwave quantum illumination
with a digital phase-conjugated receiver. In: IEEE National Radar Conference
- Proceedings. Vol 2020. IEEE; 2020. doi:10.1109/RadarConf2043947.2020.9266397'
apa: 'Barzanjeh, S., Pirandola, S., Vitali, D., & Fink, J. M. (2020). Microwave
quantum illumination with a digital phase-conjugated receiver. In IEEE National
Radar Conference - Proceedings (Vol. 2020). Florence, Italy: IEEE. https://doi.org/10.1109/RadarConf2043947.2020.9266397'
chicago: Barzanjeh, Shabir, Stefano Pirandola, David Vitali, and Johannes M Fink.
“Microwave Quantum Illumination with a Digital Phase-Conjugated Receiver.” In
IEEE National Radar Conference - Proceedings, Vol. 2020. IEEE, 2020. https://doi.org/10.1109/RadarConf2043947.2020.9266397.
ieee: S. Barzanjeh, S. Pirandola, D. Vitali, and J. M. Fink, “Microwave quantum
illumination with a digital phase-conjugated receiver,” in IEEE National Radar
Conference - Proceedings, Florence, Italy, 2020, vol. 2020, no. 9.
ista: 'Barzanjeh S, Pirandola S, Vitali D, Fink JM. 2020. Microwave quantum illumination
with a digital phase-conjugated receiver. IEEE National Radar Conference - Proceedings.
RadarConf: National Conference on Radar vol. 2020, 9266397.'
mla: Barzanjeh, Shabir, et al. “Microwave Quantum Illumination with a Digital Phase-Conjugated
Receiver.” IEEE National Radar Conference - Proceedings, vol. 2020, no.
9, 9266397, IEEE, 2020, doi:10.1109/RadarConf2043947.2020.9266397.
short: S. Barzanjeh, S. Pirandola, D. Vitali, J.M. Fink, in:, IEEE National Radar
Conference - Proceedings, IEEE, 2020.
conference:
end_date: 2020-09-25
location: Florence, Italy
name: 'RadarConf: National Conference on Radar'
start_date: 2020-09-21
date_created: 2021-01-10T23:01:17Z
date_published: 2020-09-21T00:00:00Z
date_updated: 2023-08-24T11:10:49Z
day: '21'
department:
- _id: JoFi
doi: 10.1109/RadarConf2043947.2020.9266397
ec_funded: 1
external_id:
arxiv:
- '1908.03058'
isi:
- '000612224900089'
intvolume: ' 2020'
isi: 1
issue: '9'
language:
- iso: eng
main_file_link:
- open_access: '1'
url: https://arxiv.org/abs/1908.03058
month: '09'
oa: 1
oa_version: Preprint
project:
- _id: 26336814-B435-11E9-9278-68D0E5697425
call_identifier: H2020
grant_number: '758053'
name: A Fiber Optic Transceiver for Superconducting Qubits
- _id: 237CBA6C-32DE-11EA-91FC-C7463DDC885E
call_identifier: H2020
grant_number: '862644'
name: Quantum readout techniques and technologies
- _id: 258047B6-B435-11E9-9278-68D0E5697425
call_identifier: H2020
grant_number: '707438'
name: 'Microwave-to-Optical Quantum Link: Quantum Teleportation and Quantum Illumination
with cavity Optomechanics SUPEREOM'
- _id: 257EB838-B435-11E9-9278-68D0E5697425
call_identifier: H2020
grant_number: '732894'
name: Hybrid Optomechanical Technologies
publication: IEEE National Radar Conference - Proceedings
publication_identifier:
isbn:
- '9781728189420'
issn:
- 1097-5659
publication_status: published
publisher: IEEE
quality_controlled: '1'
related_material:
record:
- id: '7910'
relation: earlier_version
status: public
scopus_import: '1'
status: public
title: Microwave quantum illumination with a digital phase-conjugated receiver
type: conference
user_id: 4359f0d1-fa6c-11eb-b949-802e58b17ae8
volume: 2020
year: '2020'
...
---
_id: '9007'
abstract:
- lang: eng
text: Motivated by a recent question of Peyre, we apply the Hardy–Littlewood circle
method to count “sufficiently free” rational points of bounded height on arbitrary
smooth projective hypersurfaces of low degree that are defined over the rationals.
article_processing_charge: No
article_type: original
author:
- first_name: Timothy D
full_name: Browning, Timothy D
id: 35827D50-F248-11E8-B48F-1D18A9856A87
last_name: Browning
orcid: 0000-0002-8314-0177
- first_name: Will
full_name: Sawin, Will
last_name: Sawin
citation:
ama: Browning TD, Sawin W. Free rational points on smooth hypersurfaces. Commentarii
Mathematici Helvetici. 2020;95(4):635-659. doi:10.4171/CMH/499
apa: Browning, T. D., & Sawin, W. (2020). Free rational points on smooth hypersurfaces.
Commentarii Mathematici Helvetici. European Mathematical Society. https://doi.org/10.4171/CMH/499
chicago: Browning, Timothy D, and Will Sawin. “Free Rational Points on Smooth Hypersurfaces.”
Commentarii Mathematici Helvetici. European Mathematical Society, 2020.
https://doi.org/10.4171/CMH/499.
ieee: T. D. Browning and W. Sawin, “Free rational points on smooth hypersurfaces,”
Commentarii Mathematici Helvetici, vol. 95, no. 4. European Mathematical
Society, pp. 635–659, 2020.
ista: Browning TD, Sawin W. 2020. Free rational points on smooth hypersurfaces.
Commentarii Mathematici Helvetici. 95(4), 635–659.
mla: Browning, Timothy D., and Will Sawin. “Free Rational Points on Smooth Hypersurfaces.”
Commentarii Mathematici Helvetici, vol. 95, no. 4, European Mathematical
Society, 2020, pp. 635–59, doi:10.4171/CMH/499.
short: T.D. Browning, W. Sawin, Commentarii Mathematici Helvetici 95 (2020) 635–659.
date_created: 2021-01-17T23:01:11Z
date_published: 2020-12-07T00:00:00Z
date_updated: 2023-08-24T11:11:36Z
day: '07'
department:
- _id: TiBr
doi: 10.4171/CMH/499
external_id:
arxiv:
- '1906.08463'
isi:
- '000596833300001'
intvolume: ' 95'
isi: 1
issue: '4'
language:
- iso: eng
main_file_link:
- open_access: '1'
url: https://arxiv.org/abs/1906.08463
month: '12'
oa: 1
oa_version: Preprint
page: 635-659
publication: Commentarii Mathematici Helvetici
publication_identifier:
eissn:
- '14208946'
issn:
- '00102571'
publication_status: published
publisher: European Mathematical Society
quality_controlled: '1'
scopus_import: '1'
status: public
title: Free rational points on smooth hypersurfaces
type: journal_article
user_id: 4359f0d1-fa6c-11eb-b949-802e58b17ae8
volume: 95
year: '2020'
...
---
_id: '9114'
abstract:
- lang: eng
text: "Microwave photonics lends the advantages of fiber optics to electronic sensing
and communication systems. In contrast to nonlinear optics, electro-optic devices
so far require classical modulation fields whose variance is dominated by electronic
or thermal noise rather than quantum fluctuations. Here we demonstrate bidirectional
single-sideband conversion of X band microwave to C band telecom light with a
microwave mode occupancy as low as 0.025 ± 0.005 and an added output noise of
less than or equal to 0.074 photons. This is facilitated by radiative cooling
and a triply resonant ultra-low-loss transducer operating at millikelvin temperatures.
The high bandwidth of 10.7 MHz and total (internal) photon conversion\r\nefficiency
of 0.03% (0.67%) combined with the extremely slow heating rate of 1.1 added output
noise photons per second for the highest available pump power of 1.48 mW puts
near-unity efficiency pulsed quantum transduction within reach. Together with
the non-Gaussian resources of superconducting qubits this might provide the practical
foundation to extend the range and scope of current quantum networks in analogy
to electrical repeaters in classical fiber optic communication."
acknowledged_ssus:
- _id: M-Shop
acknowledgement: "The authors acknowledge the support of T. Menner, A. Arslani, and
T. Asenov from the Miba machine shop for machining the microwave cavity, and thank
S. Barzanjeh, F. Sedlmeir, and C. Marquardt for fruitful discussions. This work
is supported by IST Austria and the European Research Council under Grant No. 758053
(ERC StG QUNNECT). W.H. is the recipient of an ISTplus postdoctoral fellowship with
funding from the European Union’s Horizon 2020 research and innovation program under
the Marie Skłodowska-Curie Grant No. 754411.\r\nG.A. is the recipient of a DOC fellowship
of the Austrian Academy of Sciences at IST Austria. J.M.F. acknowledges support
from the Austrian Science Fund (FWF) through BeyondC (F71) and the European Union’s
Horizon 2020 research and innovation program under Grant No. 899354 (FET Open SuperQuLAN).
H.G.L.S. acknowledges support from the Aotearoa/New Zealand’s MBIE Endeavour Smart
Ideas Grant No UOOX1805."
article_number: '020315'
article_processing_charge: No
article_type: original
author:
- first_name: William J
full_name: Hease, William J
id: 29705398-F248-11E8-B48F-1D18A9856A87
last_name: Hease
orcid: 0000-0001-9868-2166
- first_name: Alfredo R
full_name: Rueda Sanchez, Alfredo R
id: 3B82B0F8-F248-11E8-B48F-1D18A9856A87
last_name: Rueda Sanchez
orcid: 0000-0001-6249-5860
- first_name: Rishabh
full_name: Sahu, Rishabh
id: 47D26E34-F248-11E8-B48F-1D18A9856A87
last_name: Sahu
orcid: 0000-0001-6264-2162
- first_name: Matthias
full_name: Wulf, Matthias
id: 45598606-F248-11E8-B48F-1D18A9856A87
last_name: Wulf
orcid: 0000-0001-6613-1378
- first_name: Georg M
full_name: Arnold, Georg M
id: 3770C838-F248-11E8-B48F-1D18A9856A87
last_name: Arnold
orcid: 0000-0003-1397-7876
- first_name: Harald G.L.
full_name: Schwefel, Harald G.L.
last_name: Schwefel
- first_name: Johannes M
full_name: Fink, Johannes M
id: 4B591CBA-F248-11E8-B48F-1D18A9856A87
last_name: Fink
orcid: 0000-0001-8112-028X
citation:
ama: Hease WJ, Rueda Sanchez AR, Sahu R, et al. Bidirectional electro-optic wavelength
conversion in the quantum ground state. PRX Quantum. 2020;1(2). doi:10.1103/prxquantum.1.020315
apa: Hease, W. J., Rueda Sanchez, A. R., Sahu, R., Wulf, M., Arnold, G. M., Schwefel,
H. G. L., & Fink, J. M. (2020). Bidirectional electro-optic wavelength conversion
in the quantum ground state. PRX Quantum. American Physical Society. https://doi.org/10.1103/prxquantum.1.020315
chicago: Hease, William J, Alfredo R Rueda Sanchez, Rishabh Sahu, Matthias Wulf,
Georg M Arnold, Harald G.L. Schwefel, and Johannes M Fink. “Bidirectional Electro-Optic
Wavelength Conversion in the Quantum Ground State.” PRX Quantum. American
Physical Society, 2020. https://doi.org/10.1103/prxquantum.1.020315.
ieee: W. J. Hease et al., “Bidirectional electro-optic wavelength conversion
in the quantum ground state,” PRX Quantum, vol. 1, no. 2. American Physical
Society, 2020.
ista: Hease WJ, Rueda Sanchez AR, Sahu R, Wulf M, Arnold GM, Schwefel HGL, Fink
JM. 2020. Bidirectional electro-optic wavelength conversion in the quantum ground
state. PRX Quantum. 1(2), 020315.
mla: Hease, William J., et al. “Bidirectional Electro-Optic Wavelength Conversion
in the Quantum Ground State.” PRX Quantum, vol. 1, no. 2, 020315, American
Physical Society, 2020, doi:10.1103/prxquantum.1.020315.
short: W.J. Hease, A.R. Rueda Sanchez, R. Sahu, M. Wulf, G.M. Arnold, H.G.L. Schwefel,
J.M. Fink, PRX Quantum 1 (2020).
date_created: 2021-02-12T10:41:28Z
date_published: 2020-11-23T00:00:00Z
date_updated: 2023-08-24T11:16:36Z
day: '23'
ddc:
- '530'
department:
- _id: JoFi
doi: 10.1103/prxquantum.1.020315
ec_funded: 1
external_id:
isi:
- '000674680100001'
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date_created: 2021-02-12T11:16:16Z
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month: '11'
oa: 1
oa_version: Published Version
project:
- _id: 26336814-B435-11E9-9278-68D0E5697425
call_identifier: H2020
grant_number: '758053'
name: A Fiber Optic Transceiver for Superconducting Qubits
- _id: 260C2330-B435-11E9-9278-68D0E5697425
call_identifier: H2020
grant_number: '754411'
name: ISTplus - Postdoctoral Fellowships
- _id: 9B868D20-BA93-11EA-9121-9846C619BF3A
call_identifier: H2020
grant_number: '899354'
name: Quantum Local Area Networks with Superconducting Qubits
- _id: 26927A52-B435-11E9-9278-68D0E5697425
call_identifier: FWF
grant_number: F07105
name: Integrating superconducting quantum circuits
- _id: 2671EB66-B435-11E9-9278-68D0E5697425
name: Coherent on-chip conversion of superconducting qubit signals from microwaves
to optical frequencies
publication: PRX Quantum
publication_identifier:
issn:
- 2691-3399
publication_status: published
publisher: American Physical Society
quality_controlled: '1'
related_material:
link:
- description: News on IST Homepage
relation: press_release
url: https://ist.ac.at/en/news/how-to-transport-microwave-quantum-information-via-optical-fiber/
record:
- id: '13071'
relation: research_data
status: public
- id: '12900'
relation: dissertation_contains
status: public
- id: '13175'
relation: dissertation_contains
status: public
status: public
title: Bidirectional electro-optic wavelength conversion in the quantum ground state
tmp:
image: /images/cc_by.png
legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
short: CC BY (4.0)
type: journal_article
user_id: 4359f0d1-fa6c-11eb-b949-802e58b17ae8
volume: 1
year: '2020'
...
---
_id: '9194'
abstract:
- lang: eng
text: Quantum transduction, the process of converting quantum signals from one form
of energy to another, is an important area of quantum science and technology.
The present perspective article reviews quantum transduction between microwave
and optical photons, an area that has recently seen a lot of activity and progress
because of its relevance for connecting superconducting quantum processors over
long distances, among other applications. Our review covers the leading approaches
to achieving such transduction, with an emphasis on those based on atomic ensembles,
opto-electro-mechanics, and electro-optics. We briefly discuss relevant metrics
from the point of view of different applications, as well as challenges for the
future.
acknowledgement: "During the writing of this article we became aware of another review
of quantum transduction with somewhat different emphasis [99].\r\nWe would like
to thank the participants of the transduction workshop at Caltech in September 2018
for helpful and stimulating discussions. We particularly thank John Bartholomew,
Andrei Faraon, Johannes Fink, Jeff Holzgrafe, Linbo Shao, Marko Lončar, Daniel Oblak,
and Oskar Painter.\r\nN L and N S acknowledge support from the Alliance for Quantum
Technologies' (AQT) Intelligent Quantum Networks and Technologies (INQNET) research
program and by DOE/HEP QuantISED program grant, QCCFP (Quantum Communication Channels
for Fundamental Physics), award number DE-SC0019219. NS further acknowledges support
by the Natural Sciences and Engineering Research Council of Canada (NSERC). SB acknowledges
support from the Marie Skłodowska Curie fellowship number 707 438 (MSC-IF SUPEREOM).
JPC acknowledges support from the Caltech PMA prize postdoctoral fellowship. MS
acknowledges support from the ARL-CDQI and the National Science Foundation. CS acknowledges
NSERC, Quantum Alberta, and the Alberta Major Innovation Fund."
article_number: '020501'
article_processing_charge: No
article_type: review
author:
- first_name: Nikolai
full_name: Lauk, Nikolai
last_name: Lauk
- first_name: Neil
full_name: Sinclair, Neil
last_name: Sinclair
- first_name: Shabir
full_name: Barzanjeh, Shabir
id: 2D25E1F6-F248-11E8-B48F-1D18A9856A87
last_name: Barzanjeh
orcid: 0000-0003-0415-1423
- first_name: Jacob P
full_name: Covey, Jacob P
last_name: Covey
- first_name: Mark
full_name: Saffman, Mark
last_name: Saffman
- first_name: Maria
full_name: Spiropulu, Maria
last_name: Spiropulu
- first_name: Christoph
full_name: Simon, Christoph
last_name: Simon
citation:
ama: Lauk N, Sinclair N, Barzanjeh S, et al. Perspectives on quantum transduction.
Quantum Science and Technology. 2020;5(2). doi:10.1088/2058-9565/ab788a
apa: Lauk, N., Sinclair, N., Barzanjeh, S., Covey, J. P., Saffman, M., Spiropulu,
M., & Simon, C. (2020). Perspectives on quantum transduction. Quantum Science
and Technology. IOP Publishing. https://doi.org/10.1088/2058-9565/ab788a
chicago: Lauk, Nikolai, Neil Sinclair, Shabir Barzanjeh, Jacob P Covey, Mark Saffman,
Maria Spiropulu, and Christoph Simon. “Perspectives on Quantum Transduction.”
Quantum Science and Technology. IOP Publishing, 2020. https://doi.org/10.1088/2058-9565/ab788a.
ieee: N. Lauk et al., “Perspectives on quantum transduction,” Quantum
Science and Technology, vol. 5, no. 2. IOP Publishing, 2020.
ista: Lauk N, Sinclair N, Barzanjeh S, Covey JP, Saffman M, Spiropulu M, Simon C.
2020. Perspectives on quantum transduction. Quantum Science and Technology. 5(2),
020501.
mla: Lauk, Nikolai, et al. “Perspectives on Quantum Transduction.” Quantum Science
and Technology, vol. 5, no. 2, 020501, IOP Publishing, 2020, doi:10.1088/2058-9565/ab788a.
short: N. Lauk, N. Sinclair, S. Barzanjeh, J.P. Covey, M. Saffman, M. Spiropulu,
C. Simon, Quantum Science and Technology 5 (2020).
date_created: 2021-02-25T08:32:29Z
date_published: 2020-03-01T00:00:00Z
date_updated: 2023-08-24T11:17:48Z
day: '01'
ddc:
- '530'
department:
- _id: JoFi
doi: 10.1088/2058-9565/ab788a
ec_funded: 1
external_id:
isi:
- '000521449500001'
file:
- access_level: open_access
checksum: a8562c42124a66b86836fe2489eb5f4f
content_type: application/pdf
creator: dernst
date_created: 2021-03-02T09:47:13Z
date_updated: 2021-03-02T09:47:13Z
file_id: '9215'
file_name: 2020_QuantumScience_Lauk.pdf
file_size: 974399
relation: main_file
success: 1
file_date_updated: 2021-03-02T09:47:13Z
has_accepted_license: '1'
intvolume: ' 5'
isi: 1
issue: '2'
language:
- iso: eng
month: '03'
oa: 1
oa_version: Published Version
project:
- _id: 258047B6-B435-11E9-9278-68D0E5697425
call_identifier: H2020
grant_number: '707438'
name: 'Microwave-to-Optical Quantum Link: Quantum Teleportation and Quantum Illumination
with cavity Optomechanics SUPEREOM'
publication: Quantum Science and Technology
publication_identifier:
issn:
- 2058-9565
publication_status: published
publisher: IOP Publishing
quality_controlled: '1'
scopus_import: '1'
status: public
title: Perspectives on quantum transduction
tmp:
image: /images/cc_by.png
legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
short: CC BY (4.0)
type: journal_article
user_id: 4359f0d1-fa6c-11eb-b949-802e58b17ae8
volume: 5
year: '2020'
...
---
_id: '9039'
abstract:
- lang: eng
text: We give a short and self-contained proof for rates of convergence of the Allen--Cahn
equation towards mean curvature flow, assuming that a classical (smooth) solution
to the latter exists and starting from well-prepared initial data. Our approach
is based on a relative entropy technique. In particular, it does not require a
stability analysis for the linearized Allen--Cahn operator. As our analysis also
does not rely on the comparison principle, we expect it to be applicable to more
complex equations and systems.
acknowledgement: "This work was supported by the European Union's Horizon 2020 Research
and Innovation\r\nProgramme under Marie Sklodowska-Curie grant agreement 665385
and by the Deutsche\r\nForschungsgemeinschaft (DFG, German Research Foundation)
under Germany's Excellence Strategy, EXC-2047/1--390685813."
article_processing_charge: No
article_type: original
author:
- first_name: Julian L
full_name: Fischer, Julian L
id: 2C12A0B0-F248-11E8-B48F-1D18A9856A87
last_name: Fischer
orcid: 0000-0002-0479-558X
- first_name: Tim
full_name: Laux, Tim
last_name: Laux
- first_name: Theresa M.
full_name: Simon, Theresa M.
last_name: Simon
citation:
ama: 'Fischer JL, Laux T, Simon TM. Convergence rates of the Allen-Cahn equation
to mean curvature flow: A short proof based on relative entropies. SIAM Journal
on Mathematical Analysis. 2020;52(6):6222-6233. doi:10.1137/20M1322182'
apa: 'Fischer, J. L., Laux, T., & Simon, T. M. (2020). Convergence rates of
the Allen-Cahn equation to mean curvature flow: A short proof based on relative
entropies. SIAM Journal on Mathematical Analysis. Society for Industrial
and Applied Mathematics. https://doi.org/10.1137/20M1322182'
chicago: 'Fischer, Julian L, Tim Laux, and Theresa M. Simon. “Convergence Rates
of the Allen-Cahn Equation to Mean Curvature Flow: A Short Proof Based on Relative
Entropies.” SIAM Journal on Mathematical Analysis. Society for Industrial
and Applied Mathematics, 2020. https://doi.org/10.1137/20M1322182.'
ieee: 'J. L. Fischer, T. Laux, and T. M. Simon, “Convergence rates of the Allen-Cahn
equation to mean curvature flow: A short proof based on relative entropies,” SIAM
Journal on Mathematical Analysis, vol. 52, no. 6. Society for Industrial and
Applied Mathematics, pp. 6222–6233, 2020.'
ista: 'Fischer JL, Laux T, Simon TM. 2020. Convergence rates of the Allen-Cahn equation
to mean curvature flow: A short proof based on relative entropies. SIAM Journal
on Mathematical Analysis. 52(6), 6222–6233.'
mla: 'Fischer, Julian L., et al. “Convergence Rates of the Allen-Cahn Equation to
Mean Curvature Flow: A Short Proof Based on Relative Entropies.” SIAM Journal
on Mathematical Analysis, vol. 52, no. 6, Society for Industrial and Applied
Mathematics, 2020, pp. 6222–33, doi:10.1137/20M1322182.'
short: J.L. Fischer, T. Laux, T.M. Simon, SIAM Journal on Mathematical Analysis
52 (2020) 6222–6233.
date_created: 2021-01-24T23:01:09Z
date_published: 2020-12-15T00:00:00Z
date_updated: 2023-08-24T11:15:16Z
day: '15'
ddc:
- '510'
department:
- _id: JuFi
doi: 10.1137/20M1322182
ec_funded: 1
external_id:
isi:
- '000600695200027'
file:
- access_level: open_access
checksum: 21aa1cf4c30a86a00cae15a984819b5d
content_type: application/pdf
creator: dernst
date_created: 2021-01-25T07:48:39Z
date_updated: 2021-01-25T07:48:39Z
file_id: '9041'
file_name: 2020_SIAM_Fischer.pdf
file_size: 310655
relation: main_file
success: 1
file_date_updated: 2021-01-25T07:48:39Z
has_accepted_license: '1'
intvolume: ' 52'
isi: 1
issue: '6'
language:
- iso: eng
month: '12'
oa: 1
oa_version: Published Version
page: 6222-6233
project:
- _id: 2564DBCA-B435-11E9-9278-68D0E5697425
call_identifier: H2020
grant_number: '665385'
name: International IST Doctoral Program
publication: SIAM Journal on Mathematical Analysis
publication_identifier:
eissn:
- '10957154'
issn:
- '00361410'
publication_status: published
publisher: Society for Industrial and Applied Mathematics
quality_controlled: '1'
scopus_import: '1'
status: public
title: 'Convergence rates of the Allen-Cahn equation to mean curvature flow: A short
proof based on relative entropies'
tmp:
image: /images/cc_by.png
legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
short: CC BY (4.0)
type: journal_article
user_id: 4359f0d1-fa6c-11eb-b949-802e58b17ae8
volume: 52
year: '2020'
...
---
_id: '9104'
abstract:
- lang: eng
text: We consider the free additive convolution of two probability measures μ and
ν on the real line and show that μ ⊞ v is supported on a single interval if μ
and ν each has single interval support. Moreover, the density of μ ⊞ ν is proven
to vanish as a square root near the edges of its support if both μ and ν have
power law behavior with exponents between −1 and 1 near their edges. In particular,
these results show the ubiquity of the conditions in our recent work on optimal
local law at the spectral edges for addition of random matrices [5].
acknowledgement: "Supported in part by Hong Kong RGC Grant ECS 26301517.\r\nSupported
in part by ERC Advanced Grant RANMAT No. 338804.\r\nSupported in part by the Knut
and Alice Wallenberg Foundation and the Swedish Research Council Grant VR-2017-05195."
article_processing_charge: No
article_type: original
author:
- first_name: Zhigang
full_name: Bao, Zhigang
id: 442E6A6C-F248-11E8-B48F-1D18A9856A87
last_name: Bao
orcid: 0000-0003-3036-1475
- first_name: László
full_name: Erdös, László
id: 4DBD5372-F248-11E8-B48F-1D18A9856A87
last_name: Erdös
orcid: 0000-0001-5366-9603
- first_name: Kevin
full_name: Schnelli, Kevin
id: 434AD0AE-F248-11E8-B48F-1D18A9856A87
last_name: Schnelli
orcid: 0000-0003-0954-3231
citation:
ama: Bao Z, Erdös L, Schnelli K. On the support of the free additive convolution.
Journal d’Analyse Mathematique. 2020;142:323-348. doi:10.1007/s11854-020-0135-2
apa: Bao, Z., Erdös, L., & Schnelli, K. (2020). On the support of the free additive
convolution. Journal d’Analyse Mathematique. Springer Nature. https://doi.org/10.1007/s11854-020-0135-2
chicago: Bao, Zhigang, László Erdös, and Kevin Schnelli. “On the Support of the
Free Additive Convolution.” Journal d’Analyse Mathematique. Springer Nature,
2020. https://doi.org/10.1007/s11854-020-0135-2.
ieee: Z. Bao, L. Erdös, and K. Schnelli, “On the support of the free additive convolution,”
Journal d’Analyse Mathematique, vol. 142. Springer Nature, pp. 323–348,
2020.
ista: Bao Z, Erdös L, Schnelli K. 2020. On the support of the free additive convolution.
Journal d’Analyse Mathematique. 142, 323–348.
mla: Bao, Zhigang, et al. “On the Support of the Free Additive Convolution.” Journal
d’Analyse Mathematique, vol. 142, Springer Nature, 2020, pp. 323–48, doi:10.1007/s11854-020-0135-2.
short: Z. Bao, L. Erdös, K. Schnelli, Journal d’Analyse Mathematique 142 (2020)
323–348.
date_created: 2021-02-07T23:01:15Z
date_published: 2020-11-01T00:00:00Z
date_updated: 2023-08-24T11:16:03Z
day: '01'
department:
- _id: LaEr
doi: 10.1007/s11854-020-0135-2
ec_funded: 1
external_id:
arxiv:
- '1804.11199'
isi:
- '000611879400008'
intvolume: ' 142'
isi: 1
language:
- iso: eng
main_file_link:
- open_access: '1'
url: https://arxiv.org/abs/1804.11199
month: '11'
oa: 1
oa_version: Preprint
page: 323-348
project:
- _id: 258DCDE6-B435-11E9-9278-68D0E5697425
call_identifier: FP7
grant_number: '338804'
name: Random matrices, universality and disordered quantum systems
publication: Journal d'Analyse Mathematique
publication_identifier:
eissn:
- '15658538'
issn:
- '00217670'
publication_status: published
publisher: Springer Nature
quality_controlled: '1'
scopus_import: '1'
status: public
title: On the support of the free additive convolution
type: journal_article
user_id: 4359f0d1-fa6c-11eb-b949-802e58b17ae8
volume: 142
year: '2020'
...
---
_id: '13071'
abstract:
- lang: eng
text: This dataset comprises all data shown in the plots of the main part of the
submitted article "Bidirectional Electro-Optic Wavelength Conversion in the Quantum
Ground State". Additional raw data are available from the corresponding author
on reasonable request.
article_processing_charge: No
author:
- first_name: William J
full_name: Hease, William J
id: 29705398-F248-11E8-B48F-1D18A9856A87
last_name: Hease
orcid: 0000-0001-9868-2166
- first_name: Alfredo R
full_name: Rueda Sanchez, Alfredo R
id: 3B82B0F8-F248-11E8-B48F-1D18A9856A87
last_name: Rueda Sanchez
orcid: 0000-0001-6249-5860
- first_name: Rishabh
full_name: Sahu, Rishabh
id: 47D26E34-F248-11E8-B48F-1D18A9856A87
last_name: Sahu
orcid: 0000-0001-6264-2162
- first_name: Matthias
full_name: Wulf, Matthias
id: 45598606-F248-11E8-B48F-1D18A9856A87
last_name: Wulf
orcid: 0000-0001-6613-1378
- first_name: Georg M
full_name: Arnold, Georg M
id: 3770C838-F248-11E8-B48F-1D18A9856A87
last_name: Arnold
orcid: 0000-0003-1397-7876
- first_name: Harald
full_name: Schwefel, Harald
last_name: Schwefel
- first_name: Johannes M
full_name: Fink, Johannes M
id: 4B591CBA-F248-11E8-B48F-1D18A9856A87
last_name: Fink
orcid: 0000-0001-8112-028X
citation:
ama: Hease WJ, Rueda Sanchez AR, Sahu R, et al. Bidirectional electro-optic wavelength
conversion in the quantum ground state. 2020. doi:10.5281/ZENODO.4266025
apa: Hease, W. J., Rueda Sanchez, A. R., Sahu, R., Wulf, M., Arnold, G. M., Schwefel,
H., & Fink, J. M. (2020). Bidirectional electro-optic wavelength conversion
in the quantum ground state. Zenodo. https://doi.org/10.5281/ZENODO.4266025
chicago: Hease, William J, Alfredo R Rueda Sanchez, Rishabh Sahu, Matthias Wulf,
Georg M Arnold, Harald Schwefel, and Johannes M Fink. “Bidirectional Electro-Optic
Wavelength Conversion in the Quantum Ground State.” Zenodo, 2020. https://doi.org/10.5281/ZENODO.4266025.
ieee: W. J. Hease et al., “Bidirectional electro-optic wavelength conversion
in the quantum ground state.” Zenodo, 2020.
ista: Hease WJ, Rueda Sanchez AR, Sahu R, Wulf M, Arnold GM, Schwefel H, Fink JM.
2020. Bidirectional electro-optic wavelength conversion in the quantum ground
state, Zenodo, 10.5281/ZENODO.4266025.
mla: Hease, William J., et al. Bidirectional Electro-Optic Wavelength Conversion
in the Quantum Ground State. Zenodo, 2020, doi:10.5281/ZENODO.4266025.
short: W.J. Hease, A.R. Rueda Sanchez, R. Sahu, M. Wulf, G.M. Arnold, H. Schwefel,
J.M. Fink, (2020).
date_created: 2023-05-23T16:44:11Z
date_published: 2020-11-10T00:00:00Z
date_updated: 2023-08-24T11:16:35Z
day: '10'
ddc:
- '530'
department:
- _id: JoFi
doi: 10.5281/ZENODO.4266025
main_file_link:
- open_access: '1'
url: https://doi.org/10.5281/zenodo.4266026
month: '11'
oa: 1
oa_version: Published Version
publisher: Zenodo
related_material:
record:
- id: '9114'
relation: used_in_publication
status: public
status: public
title: Bidirectional electro-optic wavelength conversion in the quantum ground state
tmp:
image: /images/cc_by.png
legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
short: CC BY (4.0)
type: research_data_reference
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
year: '2020'
...
---
_id: '9195'
abstract:
- lang: eng
text: Quantum information technology based on solid state qubits has created much
interest in converting quantum states from the microwave to the optical domain.
Optical photons, unlike microwave photons, can be transmitted by fiber, making
them suitable for long distance quantum communication. Moreover, the optical domain
offers access to a large set of very well‐developed quantum optical tools, such
as highly efficient single‐photon detectors and long‐lived quantum memories. For
a high fidelity microwave to optical transducer, efficient conversion at single
photon level and low added noise is needed. Currently, the most promising approaches
to build such systems are based on second‐order nonlinear phenomena such as optomechanical
and electro‐optic interactions. Alternative approaches, although not yet as efficient,
include magneto‐optical coupling and schemes based on isolated quantum systems
like atoms, ions, or quantum dots. Herein, the necessary theoretical foundations
for the most important microwave‐to‐optical conversion experiments are provided,
their implementations are described, and the current limitations and future prospects
are discussed.
acknowledgement: The authors thank Amita Deb for useful comments on this manuscript.
The authors acknowledge support from the MBIE of New Zealand Endeavour Smart Ideas
fund. The reference numbers in Figure 8 were corrected in April 2020, after online
publication.
article_number: '1900077'
article_processing_charge: No
article_type: original
author:
- first_name: Nicholas J.
full_name: Lambert, Nicholas J.
last_name: Lambert
- first_name: Alfredo R
full_name: Rueda Sanchez, Alfredo R
id: 3B82B0F8-F248-11E8-B48F-1D18A9856A87
last_name: Rueda Sanchez
orcid: 0000-0001-6249-5860
- first_name: Florian
full_name: Sedlmeir, Florian
last_name: Sedlmeir
- first_name: Harald G. L.
full_name: Schwefel, Harald G. L.
last_name: Schwefel
citation:
ama: Lambert NJ, Rueda Sanchez AR, Sedlmeir F, Schwefel HGL. Coherent conversion
between microwave and optical photons - An overview of physical implementations.
Advanced Quantum Technologies. 2020;3(1). doi:10.1002/qute.201900077
apa: Lambert, N. J., Rueda Sanchez, A. R., Sedlmeir, F., & Schwefel, H. G. L.
(2020). Coherent conversion between microwave and optical photons - An overview
of physical implementations. Advanced Quantum Technologies. Wiley. https://doi.org/10.1002/qute.201900077
chicago: Lambert, Nicholas J., Alfredo R Rueda Sanchez, Florian Sedlmeir, and Harald
G. L. Schwefel. “Coherent Conversion between Microwave and Optical Photons - An
Overview of Physical Implementations.” Advanced Quantum Technologies. Wiley,
2020. https://doi.org/10.1002/qute.201900077.
ieee: N. J. Lambert, A. R. Rueda Sanchez, F. Sedlmeir, and H. G. L. Schwefel, “Coherent
conversion between microwave and optical photons - An overview of physical implementations,”
Advanced Quantum Technologies, vol. 3, no. 1. Wiley, 2020.
ista: Lambert NJ, Rueda Sanchez AR, Sedlmeir F, Schwefel HGL. 2020. Coherent conversion
between microwave and optical photons - An overview of physical implementations.
Advanced Quantum Technologies. 3(1), 1900077.
mla: Lambert, Nicholas J., et al. “Coherent Conversion between Microwave and Optical
Photons - An Overview of Physical Implementations.” Advanced Quantum Technologies,
vol. 3, no. 1, 1900077, Wiley, 2020, doi:10.1002/qute.201900077.
short: N.J. Lambert, A.R. Rueda Sanchez, F. Sedlmeir, H.G.L. Schwefel, Advanced
Quantum Technologies 3 (2020).
date_created: 2021-02-25T08:52:36Z
date_published: 2020-01-01T00:00:00Z
date_updated: 2023-08-24T13:53:02Z
day: '01'
ddc:
- '530'
department:
- _id: JoFi
doi: 10.1002/qute.201900077
external_id:
isi:
- '000548088300001'
file:
- access_level: open_access
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date_updated: 2021-03-02T12:30:03Z
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file_name: 2020_AdvQuantumTech_Lambert.pdf
file_size: 2410114
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isi: 1
issue: '1'
language:
- iso: eng
license: https://creativecommons.org/licenses/by-nc/4.0/
month: '01'
oa: 1
oa_version: Published Version
publication: Advanced Quantum Technologies
publication_identifier:
issn:
- 2511-9044
publication_status: published
publisher: Wiley
quality_controlled: '1'
related_material:
link:
- description: Cover Page
relation: poster
url: https://doi.org/10.1002/qute.202070011
status: public
title: Coherent conversion between microwave and optical photons - An overview of
physical implementations
tmp:
image: /images/cc_by_nc.png
legal_code_url: https://creativecommons.org/licenses/by-nc/4.0/legalcode
name: Creative Commons Attribution-NonCommercial 4.0 International (CC BY-NC 4.0)
short: CC BY-NC (4.0)
type: journal_article
user_id: 4359f0d1-fa6c-11eb-b949-802e58b17ae8
volume: 3
year: '2020'
...
---
_id: '9011'
abstract:
- lang: eng
text: "Distributed ledgers provide high availability and integrity, making them
a key enabler for practical and secure computation of distributed workloads among
mutually distrustful parties. Many practical applications also require strong
confidentiality, however. This work enhances permissioned and permissionless blockchains
with the ability to manage confidential data without forfeiting availability or
decentralization. The proposed Calypso architecture addresses two orthogonal challenges
confronting modern distributed ledgers: (a) enabling the auditable management
of secrets and (b) protecting distributed computations against arbitrage attacks
when their results depend on the ordering and secrecy of inputs.\r\n\r\nCalypso
introduces on-chain secrets, a novel abstraction that enforces atomic deposition
of an auditable trace whenever users access confidential data. Calypso provides
user-controlled consent management that ensures revocation atomicity and accountable
anonymity. To enable permissionless deployment, we introduce an incentive scheme
and provide users with the option to select their preferred trustees. We evaluated
our Calypso prototype with a confidential document-sharing application and a decentralized
lottery. Our benchmarks show that transaction-processing latency increases linearly
in terms of security (number of trustees) and is in the range of 0.2 to 8 seconds
for 16 to 128 trustees."
acknowledgement: 'We thank Nicolas Gailly, Vincent Graf, Jean-Pierre Hubaux, Wouter
Lueks, Massimo Marelli, Carmela Troncoso, Juan-Ramón Troncoso Pastoriza, Frédéric
Pont, and Sandra Siby for their valuable feedback. This project was supported in
part by the ETH domain under PHRT grant #2017−201, and by the AXA Research Fund,
Byzgen, DFINITY, and the Swiss Data Science Center (SDSC).'
article_processing_charge: No
article_type: original
author:
- first_name: Eleftherios
full_name: Kokoris Kogias, Eleftherios
id: f5983044-d7ef-11ea-ac6d-fd1430a26d30
last_name: Kokoris Kogias
- first_name: Enis Ceyhun
full_name: Alp, Enis Ceyhun
last_name: Alp
- first_name: Linus
full_name: Gasser, Linus
last_name: Gasser
- first_name: Philipp
full_name: Jovanovic, Philipp
last_name: Jovanovic
- first_name: Ewa
full_name: Syta, Ewa
last_name: Syta
- first_name: Bryan
full_name: Ford, Bryan
last_name: Ford
citation:
ama: 'Kokoris Kogias E, Alp EC, Gasser L, Jovanovic P, Syta E, Ford B. CALYPSO:
Private data management for decentralized ledgers. Proceedings of the VLDB
Endowment. 2020;14(4):586-599. doi:10.14778/3436905.3436917'
apa: 'Kokoris Kogias, E., Alp, E. C., Gasser, L., Jovanovic, P., Syta, E., &
Ford, B. (2020). CALYPSO: Private data management for decentralized ledgers. Proceedings
of the VLDB Endowment. Association for Computing Machinery. https://doi.org/10.14778/3436905.3436917'
chicago: 'Kokoris Kogias, Eleftherios, Enis Ceyhun Alp, Linus Gasser, Philipp Jovanovic,
Ewa Syta, and Bryan Ford. “CALYPSO: Private Data Management for Decentralized
Ledgers.” Proceedings of the VLDB Endowment. Association for Computing
Machinery, 2020. https://doi.org/10.14778/3436905.3436917.'
ieee: 'E. Kokoris Kogias, E. C. Alp, L. Gasser, P. Jovanovic, E. Syta, and B. Ford,
“CALYPSO: Private data management for decentralized ledgers,” Proceedings of
the VLDB Endowment, vol. 14, no. 4. Association for Computing Machinery, pp.
586–599, 2020.'
ista: 'Kokoris Kogias E, Alp EC, Gasser L, Jovanovic P, Syta E, Ford B. 2020. CALYPSO:
Private data management for decentralized ledgers. Proceedings of the VLDB Endowment.
14(4), 586–599.'
mla: 'Kokoris Kogias, Eleftherios, et al. “CALYPSO: Private Data Management for
Decentralized Ledgers.” Proceedings of the VLDB Endowment, vol. 14, no.
4, Association for Computing Machinery, 2020, pp. 586–99, doi:10.14778/3436905.3436917.'
short: E. Kokoris Kogias, E.C. Alp, L. Gasser, P. Jovanovic, E. Syta, B. Ford, Proceedings
of the VLDB Endowment 14 (2020) 586–599.
date_created: 2021-01-17T23:01:13Z
date_published: 2020-12-01T00:00:00Z
date_updated: 2023-08-24T13:57:13Z
day: '01'
department:
- _id: ElKo
doi: 10.14778/3436905.3436917
external_id:
isi:
- '000658495400012'
intvolume: ' 14'
isi: 1
issue: '4'
language:
- iso: eng
main_file_link:
- open_access: '1'
url: https://dl.acm.org/doi/10.14778/3436905.3436917
month: '12'
oa: 1
oa_version: Published Version
page: 586-599
publication: Proceedings of the VLDB Endowment
publication_identifier:
eissn:
- 2150-8097
publication_status: published
publisher: Association for Computing Machinery
quality_controlled: '1'
scopus_import: '1'
status: public
title: 'CALYPSO: Private data management for decentralized ledgers'
tmp:
image: /images/cc_by_nc_nd.png
legal_code_url: https://creativecommons.org/licenses/by-nc-nd/4.0/legalcode
name: Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International
(CC BY-NC-ND 4.0)
short: CC BY-NC-ND (4.0)
type: journal_article
user_id: 4359f0d1-fa6c-11eb-b949-802e58b17ae8
volume: 14
year: '2020'
...
---
_id: '8308'
abstract:
- lang: eng
text: 'Many-body localization provides a mechanism to avoid thermalization in isolated
interacting quantum systems. The breakdown of thermalization may be complete,
when all eigenstates in the many-body spectrum become localized, or partial, when
the so-called many-body mobility edge separates localized and delocalized parts
of the spectrum. Previously, De Roeck et al. [Phys. Rev. B 93, 014203 (2016)]
suggested a possible instability of the many-body mobility edge in energy density.
The local ergodic regions—so-called “bubbles”—resonantly spread throughout the
system, leading to delocalization. In order to study such instability mechanism,
in this work we design a model featuring many-body mobility edge in particle density:
the states at small particle density are localized, while increasing the density
of particles leads to delocalization. Using numerical simulations with matrix
product states, we demonstrate the stability of many-body localization with respect
to small bubbles in large dilute systems for experimentally relevant timescales.
In addition, we demonstrate that processes where the bubble spreads are favored
over processes that lead to resonant tunneling, suggesting a possible mechanism
behind the observed stability of many-body mobility edge. We conclude by proposing
experiments to probe particle density mobility edge in the Bose-Hubbard model.'
acknowledgement: 'Acknowledgments. We acknowledge useful discussions with W. De Roeck
and A. Michailidis. P.B. was supported by the European Union''s Horizon 2020 research
and innovation program under the Marie Sklodowska-Curie Grant Agreement No. 665385.
D.A. was supported by the Swiss National Science Foundation. M.S. was supported
by European Research Council (ERC) under the European Union''s Horizon 2020 research
and innovation program (Grant Agreement No. 850899). This work benefited from visits
to KITP, supported by the National Science Foundation under Grant No. NSF PHY-1748958
and from the program “Thermalization, Many Body Localization and Hydrodynamics”
at International Centre for Theoretical Sciences (Code: ICTS/hydrodynamics2019/11).'
article_number: 060202(R)
article_processing_charge: No
article_type: original
author:
- first_name: Pietro
full_name: Brighi, Pietro
id: 4115AF5C-F248-11E8-B48F-1D18A9856A87
last_name: Brighi
orcid: 0000-0002-7969-2729
- first_name: Dmitry A.
full_name: Abanin, Dmitry A.
last_name: Abanin
- first_name: Maksym
full_name: Serbyn, Maksym
id: 47809E7E-F248-11E8-B48F-1D18A9856A87
last_name: Serbyn
orcid: 0000-0002-2399-5827
citation:
ama: Brighi P, Abanin DA, Serbyn M. Stability of mobility edges in disordered interacting
systems. Physical Review B. 2020;102(6). doi:10.1103/physrevb.102.060202
apa: Brighi, P., Abanin, D. A., & Serbyn, M. (2020). Stability of mobility edges
in disordered interacting systems. Physical Review B. American Physical
Society. https://doi.org/10.1103/physrevb.102.060202
chicago: Brighi, Pietro, Dmitry A. Abanin, and Maksym Serbyn. “Stability of Mobility
Edges in Disordered Interacting Systems.” Physical Review B. American Physical
Society, 2020. https://doi.org/10.1103/physrevb.102.060202.
ieee: P. Brighi, D. A. Abanin, and M. Serbyn, “Stability of mobility edges in disordered
interacting systems,” Physical Review B, vol. 102, no. 6. American Physical
Society, 2020.
ista: Brighi P, Abanin DA, Serbyn M. 2020. Stability of mobility edges in disordered
interacting systems. Physical Review B. 102(6), 060202(R).
mla: Brighi, Pietro, et al. “Stability of Mobility Edges in Disordered Interacting
Systems.” Physical Review B, vol. 102, no. 6, 060202(R), American Physical
Society, 2020, doi:10.1103/physrevb.102.060202.
short: P. Brighi, D.A. Abanin, M. Serbyn, Physical Review B 102 (2020).
date_created: 2020-08-26T19:27:42Z
date_published: 2020-08-26T00:00:00Z
date_updated: 2023-08-24T14:20:21Z
day: '26'
ddc:
- '530'
department:
- _id: MaSe
doi: 10.1103/physrevb.102.060202
ec_funded: 1
external_id:
isi:
- '000562628300001'
file:
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checksum: 716442fa7861323fcc80b93718ca009c
content_type: application/pdf
creator: mserbyn
date_created: 2020-08-26T19:28:55Z
date_updated: 2020-08-26T19:28:55Z
file_id: '8309'
file_name: PhysRevB.102.060202.pdf
file_size: 488825
relation: main_file
success: 1
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content_type: application/pdf
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date_created: 2020-08-26T19:29:00Z
date_updated: 2020-08-26T19:29:00Z
file_id: '8310'
file_name: Supplementary-mbme.pdf
file_size: 711405
relation: main_file
success: 1
file_date_updated: 2020-08-26T19:29:00Z
has_accepted_license: '1'
intvolume: ' 102'
isi: 1
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language:
- iso: eng
month: '08'
oa: 1
oa_version: None
project:
- _id: 2564DBCA-B435-11E9-9278-68D0E5697425
call_identifier: H2020
grant_number: '665385'
name: International IST Doctoral Program
- _id: 23841C26-32DE-11EA-91FC-C7463DDC885E
call_identifier: H2020
grant_number: '850899'
name: 'Non-Ergodic Quantum Matter: Universality, Dynamics and Control'
publication: Physical Review B
publication_identifier:
eissn:
- 2469-9969
issn:
- 2469-9950
publication_status: published
publisher: American Physical Society
quality_controlled: '1'
related_material:
record:
- id: '12732'
relation: dissertation_contains
status: public
scopus_import: '1'
status: public
title: Stability of mobility edges in disordered interacting systems
type: journal_article
user_id: 4359f0d1-fa6c-11eb-b949-802e58b17ae8
volume: 102
year: '2020'
...
---
_id: '10862'
abstract:
- lang: eng
text: We consider the sum of two large Hermitian matrices A and B with a Haar unitary
conjugation bringing them into a general relative position. We prove that the
eigenvalue density on the scale slightly above the local eigenvalue spacing is
asymptotically given by the free additive convolution of the laws of A and B as
the dimension of the matrix increases. This implies optimal rigidity of the eigenvalues
and optimal rate of convergence in Voiculescu's theorem. Our previous works [4],
[5] established these results in the bulk spectrum, the current paper completely
settles the problem at the spectral edges provided they have the typical square-root
behavior. The key element of our proof is to compensate the deterioration of the
stability of the subordination equations by sharp error estimates that properly
account for the local density near the edge. Our results also hold if the Haar
unitary matrix is replaced by the Haar orthogonal matrix.
acknowledgement: Partially supported by ERC Advanced Grant RANMAT No. 338804.
article_number: '108639'
article_processing_charge: No
article_type: original
author:
- first_name: Zhigang
full_name: Bao, Zhigang
id: 442E6A6C-F248-11E8-B48F-1D18A9856A87
last_name: Bao
orcid: 0000-0003-3036-1475
- first_name: László
full_name: Erdös, László
id: 4DBD5372-F248-11E8-B48F-1D18A9856A87
last_name: Erdös
orcid: 0000-0001-5366-9603
- first_name: Kevin
full_name: Schnelli, Kevin
last_name: Schnelli
citation:
ama: Bao Z, Erdös L, Schnelli K. Spectral rigidity for addition of random matrices
at the regular edge. Journal of Functional Analysis. 2020;279(7). doi:10.1016/j.jfa.2020.108639
apa: Bao, Z., Erdös, L., & Schnelli, K. (2020). Spectral rigidity for addition
of random matrices at the regular edge. Journal of Functional Analysis.
Elsevier. https://doi.org/10.1016/j.jfa.2020.108639
chicago: Bao, Zhigang, László Erdös, and Kevin Schnelli. “Spectral Rigidity for
Addition of Random Matrices at the Regular Edge.” Journal of Functional Analysis.
Elsevier, 2020. https://doi.org/10.1016/j.jfa.2020.108639.
ieee: Z. Bao, L. Erdös, and K. Schnelli, “Spectral rigidity for addition of random
matrices at the regular edge,” Journal of Functional Analysis, vol. 279,
no. 7. Elsevier, 2020.
ista: Bao Z, Erdös L, Schnelli K. 2020. Spectral rigidity for addition of random
matrices at the regular edge. Journal of Functional Analysis. 279(7), 108639.
mla: Bao, Zhigang, et al. “Spectral Rigidity for Addition of Random Matrices at
the Regular Edge.” Journal of Functional Analysis, vol. 279, no. 7, 108639,
Elsevier, 2020, doi:10.1016/j.jfa.2020.108639.
short: Z. Bao, L. Erdös, K. Schnelli, Journal of Functional Analysis 279 (2020).
date_created: 2022-03-18T10:18:59Z
date_published: 2020-10-15T00:00:00Z
date_updated: 2023-08-24T14:08:42Z
day: '15'
department:
- _id: LaEr
doi: 10.1016/j.jfa.2020.108639
ec_funded: 1
external_id:
arxiv:
- '1708.01597'
isi:
- '000559623200009'
intvolume: ' 279'
isi: 1
issue: '7'
keyword:
- Analysis
language:
- iso: eng
main_file_link:
- open_access: '1'
url: https://arxiv.org/abs/1708.01597
month: '10'
oa: 1
oa_version: Preprint
project:
- _id: 258DCDE6-B435-11E9-9278-68D0E5697425
call_identifier: FP7
grant_number: '338804'
name: Random matrices, universality and disordered quantum systems
publication: Journal of Functional Analysis
publication_identifier:
issn:
- 0022-1236
publication_status: published
publisher: Elsevier
quality_controlled: '1'
scopus_import: '1'
status: public
title: Spectral rigidity for addition of random matrices at the regular edge
type: journal_article
user_id: 4359f0d1-fa6c-11eb-b949-802e58b17ae8
volume: 279
year: '2020'
...
---
_id: '10867'
abstract:
- lang: eng
text: In this paper we find a tight estimate for Gromov’s waist of the balls in
spaces of constant curvature, deduce the estimates for the balls in Riemannian
manifolds with upper bounds on the curvature (CAT(ϰ)-spaces), and establish similar
result for normed spaces.
acknowledgement: ' Supported by the Russian Foundation for Basic Research grant 18-01-00036.'
article_processing_charge: No
article_type: original
author:
- first_name: Arseniy
full_name: Akopyan, Arseniy
id: 430D2C90-F248-11E8-B48F-1D18A9856A87
last_name: Akopyan
orcid: 0000-0002-2548-617X
- first_name: Roman
full_name: Karasev, Roman
last_name: Karasev
citation:
ama: Akopyan A, Karasev R. Waist of balls in hyperbolic and spherical spaces. International
Mathematics Research Notices. 2020;2020(3):669-697. doi:10.1093/imrn/rny037
apa: Akopyan, A., & Karasev, R. (2020). Waist of balls in hyperbolic and spherical
spaces. International Mathematics Research Notices. Oxford University Press.
https://doi.org/10.1093/imrn/rny037
chicago: Akopyan, Arseniy, and Roman Karasev. “Waist of Balls in Hyperbolic and
Spherical Spaces.” International Mathematics Research Notices. Oxford University
Press, 2020. https://doi.org/10.1093/imrn/rny037.
ieee: A. Akopyan and R. Karasev, “Waist of balls in hyperbolic and spherical spaces,”
International Mathematics Research Notices, vol. 2020, no. 3. Oxford University
Press, pp. 669–697, 2020.
ista: Akopyan A, Karasev R. 2020. Waist of balls in hyperbolic and spherical spaces.
International Mathematics Research Notices. 2020(3), 669–697.
mla: Akopyan, Arseniy, and Roman Karasev. “Waist of Balls in Hyperbolic and Spherical
Spaces.” International Mathematics Research Notices, vol. 2020, no. 3,
Oxford University Press, 2020, pp. 669–97, doi:10.1093/imrn/rny037.
short: A. Akopyan, R. Karasev, International Mathematics Research Notices 2020 (2020)
669–697.
date_created: 2022-03-18T11:39:30Z
date_published: 2020-02-01T00:00:00Z
date_updated: 2023-08-24T14:19:55Z
day: '01'
department:
- _id: HeEd
doi: 10.1093/imrn/rny037
external_id:
arxiv:
- '1702.07513'
isi:
- '000522852700002'
intvolume: ' 2020'
isi: 1
issue: '3'
keyword:
- General Mathematics
language:
- iso: eng
main_file_link:
- open_access: '1'
url: https://arxiv.org/abs/1702.07513
month: '02'
oa: 1
oa_version: Preprint
page: 669-697
publication: International Mathematics Research Notices
publication_identifier:
eissn:
- 1687-0247
issn:
- 1073-7928
publication_status: published
publisher: Oxford University Press
quality_controlled: '1'
scopus_import: '1'
status: public
title: Waist of balls in hyperbolic and spherical spaces
type: journal_article
user_id: 4359f0d1-fa6c-11eb-b949-802e58b17ae8
volume: 2020
year: '2020'
...
---
_id: '9799'
abstract:
- lang: eng
text: Fitness interactions between mutations can influence a population’s evolution
in many different ways. While epistatic effects are difficult to measure precisely,
important information is captured by the mean and variance of log fitnesses for
individuals carrying different numbers of mutations. We derive predictions for
these quantities from a class of simple fitness landscapes, based on models of
optimizing selection on quantitative traits. We also explore extensions to the
models, including modular pleiotropy, variable effect sizes, mutational bias and
maladaptation of the wild type. We illustrate our approach by reanalysing a large
dataset of mutant effects in a yeast snoRNA. Though characterized by some large
epistatic effects, these data give a good overall fit to the non-epistatic null
model, suggesting that epistasis might have limited influence on the evolutionary
dynamics in this system. We also show how the amount of epistasis depends on both
the underlying fitness landscape and the distribution of mutations, and so is
expected to vary in consistent ways between new mutations, standing variation
and fixed mutations.
article_processing_charge: No
author:
- first_name: Christelle
full_name: Fraisse, Christelle
id: 32DF5794-F248-11E8-B48F-1D18A9856A87
last_name: Fraisse
orcid: 0000-0001-8441-5075
- first_name: John J.
full_name: Welch, John J.
last_name: Welch
citation:
ama: Fraisse C, Welch JJ. Simulation code for Fig S1 from the distribution of epistasis
on simple fitness landscapes. 2020. doi:10.6084/m9.figshare.7957469.v1
apa: Fraisse, C., & Welch, J. J. (2020). Simulation code for Fig S1 from the
distribution of epistasis on simple fitness landscapes. Royal Society of London.
https://doi.org/10.6084/m9.figshare.7957469.v1
chicago: Fraisse, Christelle, and John J. Welch. “Simulation Code for Fig S1 from
the Distribution of Epistasis on Simple Fitness Landscapes.” Royal Society of
London, 2020. https://doi.org/10.6084/m9.figshare.7957469.v1.
ieee: C. Fraisse and J. J. Welch, “Simulation code for Fig S1 from the distribution
of epistasis on simple fitness landscapes.” Royal Society of London, 2020.
ista: Fraisse C, Welch JJ. 2020. Simulation code for Fig S1 from the distribution
of epistasis on simple fitness landscapes, Royal Society of London, 10.6084/m9.figshare.7957469.v1.
mla: Fraisse, Christelle, and John J. Welch. Simulation Code for Fig S1 from
the Distribution of Epistasis on Simple Fitness Landscapes. Royal Society
of London, 2020, doi:10.6084/m9.figshare.7957469.v1.
short: C. Fraisse, J.J. Welch, (2020).
date_created: 2021-08-06T11:26:57Z
date_published: 2020-10-15T00:00:00Z
date_updated: 2023-08-25T10:34:41Z
day: '15'
department:
- _id: BeVi
- _id: NiBa
doi: 10.6084/m9.figshare.7957469.v1
main_file_link:
- open_access: '1'
url: https://doi.org/10.6084/m9.figshare.7957469.v1
month: '10'
oa: 1
oa_version: Published Version
publisher: Royal Society of London
related_material:
record:
- id: '6467'
relation: used_in_publication
status: public
status: public
title: Simulation code for Fig S1 from the distribution of epistasis on simple fitness
landscapes
type: research_data_reference
user_id: 6785fbc1-c503-11eb-8a32-93094b40e1cf
year: '2020'
...
---
_id: '9798'
abstract:
- lang: eng
text: Fitness interactions between mutations can influence a population’s evolution
in many different ways. While epistatic effects are difficult to measure precisely,
important information is captured by the mean and variance of log fitnesses for
individuals carrying different numbers of mutations. We derive predictions for
these quantities from a class of simple fitness landscapes, based on models of
optimizing selection on quantitative traits. We also explore extensions to the
models, including modular pleiotropy, variable effect sizes, mutational bias and
maladaptation of the wild type. We illustrate our approach by reanalysing a large
dataset of mutant effects in a yeast snoRNA. Though characterized by some large
epistatic effects, these data give a good overall fit to the non-epistatic null
model, suggesting that epistasis might have limited influence on the evolutionary
dynamics in this system. We also show how the amount of epistasis depends on both
the underlying fitness landscape and the distribution of mutations, and so is
expected to vary in consistent ways between new mutations, standing variation
and fixed mutations.
article_processing_charge: No
author:
- first_name: Christelle
full_name: Fraisse, Christelle
id: 32DF5794-F248-11E8-B48F-1D18A9856A87
last_name: Fraisse
orcid: 0000-0001-8441-5075
- first_name: John J.
full_name: Welch, John J.
last_name: Welch
citation:
ama: Fraisse C, Welch JJ. Simulation code for Fig S2 from the distribution of epistasis
on simple fitness landscapes. 2020. doi:10.6084/m9.figshare.7957472.v1
apa: Fraisse, C., & Welch, J. J. (2020). Simulation code for Fig S2 from the
distribution of epistasis on simple fitness landscapes. Royal Society of London.
https://doi.org/10.6084/m9.figshare.7957472.v1
chicago: Fraisse, Christelle, and John J. Welch. “Simulation Code for Fig S2 from
the Distribution of Epistasis on Simple Fitness Landscapes.” Royal Society of
London, 2020. https://doi.org/10.6084/m9.figshare.7957472.v1.
ieee: C. Fraisse and J. J. Welch, “Simulation code for Fig S2 from the distribution
of epistasis on simple fitness landscapes.” Royal Society of London, 2020.
ista: Fraisse C, Welch JJ. 2020. Simulation code for Fig S2 from the distribution
of epistasis on simple fitness landscapes, Royal Society of London, 10.6084/m9.figshare.7957472.v1.
mla: Fraisse, Christelle, and John J. Welch. Simulation Code for Fig S2 from
the Distribution of Epistasis on Simple Fitness Landscapes. Royal Society
of London, 2020, doi:10.6084/m9.figshare.7957472.v1.
short: C. Fraisse, J.J. Welch, (2020).
date_created: 2021-08-06T11:18:15Z
date_published: 2020-10-15T00:00:00Z
date_updated: 2023-08-25T10:34:41Z
day: '15'
department:
- _id: BeVi
- _id: NiBa
doi: 10.6084/m9.figshare.7957472.v1
main_file_link:
- open_access: '1'
url: https://doi.org/10.6084/m9.figshare.7957472.v1
month: '10'
oa: 1
oa_version: Published Version
publisher: Royal Society of London
related_material:
record:
- id: '6467'
relation: used_in_publication
status: public
status: public
title: Simulation code for Fig S2 from the distribution of epistasis on simple fitness
landscapes
type: research_data_reference
user_id: 6785fbc1-c503-11eb-8a32-93094b40e1cf
year: '2020'
...
---
_id: '6488'
abstract:
- lang: eng
text: We prove a central limit theorem for the difference of linear eigenvalue statistics
of a sample covariance matrix W˜ and its minor W. We find that the fluctuation
of this difference is much smaller than those of the individual linear statistics,
as a consequence of the strong correlation between the eigenvalues of W˜ and W.
Our result identifies the fluctuation of the spatial derivative of the approximate
Gaussian field in the recent paper by Dumitru and Paquette. Unlike in a similar
result for Wigner matrices, for sample covariance matrices, the fluctuation may
entirely vanish.
article_number: '2050006'
article_processing_charge: No
article_type: original
author:
- first_name: Giorgio
full_name: Cipolloni, Giorgio
id: 42198EFA-F248-11E8-B48F-1D18A9856A87
last_name: Cipolloni
orcid: 0000-0002-4901-7992
- first_name: László
full_name: Erdös, László
id: 4DBD5372-F248-11E8-B48F-1D18A9856A87
last_name: Erdös
orcid: 0000-0001-5366-9603
citation:
ama: 'Cipolloni G, Erdös L. Fluctuations for differences of linear eigenvalue statistics
for sample covariance matrices. Random Matrices: Theory and Application.
2020;9(3). doi:10.1142/S2010326320500069'
apa: 'Cipolloni, G., & Erdös, L. (2020). Fluctuations for differences of linear
eigenvalue statistics for sample covariance matrices. Random Matrices: Theory
and Application. World Scientific Publishing. https://doi.org/10.1142/S2010326320500069'
chicago: 'Cipolloni, Giorgio, and László Erdös. “Fluctuations for Differences of
Linear Eigenvalue Statistics for Sample Covariance Matrices.” Random Matrices:
Theory and Application. World Scientific Publishing, 2020. https://doi.org/10.1142/S2010326320500069.'
ieee: 'G. Cipolloni and L. Erdös, “Fluctuations for differences of linear eigenvalue
statistics for sample covariance matrices,” Random Matrices: Theory and Application,
vol. 9, no. 3. World Scientific Publishing, 2020.'
ista: 'Cipolloni G, Erdös L. 2020. Fluctuations for differences of linear eigenvalue
statistics for sample covariance matrices. Random Matrices: Theory and Application.
9(3), 2050006.'
mla: 'Cipolloni, Giorgio, and László Erdös. “Fluctuations for Differences of Linear
Eigenvalue Statistics for Sample Covariance Matrices.” Random Matrices: Theory
and Application, vol. 9, no. 3, 2050006, World Scientific Publishing, 2020,
doi:10.1142/S2010326320500069.'
short: 'G. Cipolloni, L. Erdös, Random Matrices: Theory and Application 9 (2020).'
date_created: 2019-05-26T21:59:14Z
date_published: 2020-07-01T00:00:00Z
date_updated: 2023-08-28T08:38:48Z
day: '01'
department:
- _id: LaEr
doi: 10.1142/S2010326320500069
ec_funded: 1
external_id:
arxiv:
- '1806.08751'
isi:
- '000547464400001'
intvolume: ' 9'
isi: 1
issue: '3'
language:
- iso: eng
main_file_link:
- open_access: '1'
url: https://arxiv.org/abs/1806.08751
month: '07'
oa: 1
oa_version: Preprint
project:
- _id: 258DCDE6-B435-11E9-9278-68D0E5697425
call_identifier: FP7
grant_number: '338804'
name: Random matrices, universality and disordered quantum systems
- _id: 2564DBCA-B435-11E9-9278-68D0E5697425
call_identifier: H2020
grant_number: '665385'
name: International IST Doctoral Program
publication: 'Random Matrices: Theory and Application'
publication_identifier:
eissn:
- '20103271'
issn:
- '20103263'
publication_status: published
publisher: World Scientific Publishing
quality_controlled: '1'
scopus_import: '1'
status: public
title: Fluctuations for differences of linear eigenvalue statistics for sample covariance
matrices
type: journal_article
user_id: 4359f0d1-fa6c-11eb-b949-802e58b17ae8
volume: 9
year: '2020'
...