--- _id: '7284' abstract: - lang: eng text: In this issue of Joule, Dongmin Im and coworkers from Samsung in South Korea describe a prototype lithium-O2 battery that reaches ∼700 Wh kg–1 and ∼600 Wh L–1 on the cell level. They cut all components to the minimum to reach this value. Difficulties filling the pores with discharge product and inhomogeneous cell utilization turn out to limit the achievable energy. Their work underlines the importance of reporting performance with respect to full cell weight and volume. article_processing_charge: No article_type: review author: - first_name: Christian full_name: Prehal, Christian last_name: Prehal - first_name: Stefan Alexander full_name: Freunberger, Stefan Alexander id: A8CA28E6-CE23-11E9-AD2D-EC27E6697425 last_name: Freunberger orcid: 0000-0003-2902-5319 citation: ama: Prehal C, Freunberger SA. Li-O2 cell-scale energy densities. Joule. 2019;3(2):321-323. doi:10.1016/j.joule.2019.01.020 apa: Prehal, C., & Freunberger, S. A. (2019). Li-O2 cell-scale energy densities. Joule. Elsevier. https://doi.org/10.1016/j.joule.2019.01.020 chicago: Prehal, Christian, and Stefan Alexander Freunberger. “Li-O2 Cell-Scale Energy Densities.” Joule. Elsevier, 2019. https://doi.org/10.1016/j.joule.2019.01.020. ieee: C. Prehal and S. A. Freunberger, “Li-O2 cell-scale energy densities,” Joule, vol. 3, no. 2. Elsevier, pp. 321–323, 2019. ista: Prehal C, Freunberger SA. 2019. Li-O2 cell-scale energy densities. Joule. 3(2), 321–323. mla: Prehal, Christian, and Stefan Alexander Freunberger. “Li-O2 Cell-Scale Energy Densities.” Joule, vol. 3, no. 2, Elsevier, 2019, pp. 321–23, doi:10.1016/j.joule.2019.01.020. short: C. Prehal, S.A. Freunberger, Joule 3 (2019) 321–323. date_created: 2020-01-15T12:13:15Z date_published: 2019-02-20T00:00:00Z date_updated: 2021-01-12T08:12:45Z day: '20' doi: 10.1016/j.joule.2019.01.020 extern: '1' intvolume: ' 3' issue: '2' language: - iso: eng main_file_link: - open_access: '1' url: https://www.doi.org/10.1016/j.joule.2019.01.020 month: '02' oa: 1 oa_version: Published Version page: 321-323 publication: Joule publication_identifier: issn: - 2542-4351 publication_status: published publisher: Elsevier quality_controlled: '1' status: public title: Li-O2 cell-scale energy densities type: journal_article user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87 volume: 3 year: '2019' ... --- _id: '7358' abstract: - lang: eng text: Telencephalic organoids generated from human pluripotent stem cells (hPSCs) are emerging as an effective system to study the distinct features of the developing human brain and the underlying causes of many neurological disorders. While progress in organoid technology has been steadily advancing, many challenges remain including rampant batch-to-batch and cell line-to-cell line variability and irreproducibility. Here, we demonstrate that a major contributor to successful cortical organoid production is the manner in which hPSCs are maintained prior to differentiation. Optimal results were achieved using fibroblast-feeder-supported hPSCs compared to feeder-independent cells, related to differences in their transcriptomic states. Feeder-supported hPSCs display elevated activation of diverse TGFβ superfamily signaling pathways and increased expression of genes associated with naïve pluripotency. We further identify combinations of TGFβ-related growth factors that are necessary and together sufficient to impart broad telencephalic organoid competency to feeder-free hPSCs and enable reproducible formation of brain structures suitable for disease modeling. article_processing_charge: No author: - first_name: Momoko full_name: Watanabe, Momoko last_name: Watanabe - first_name: Jillian R. full_name: Haney, Jillian R. last_name: Haney - first_name: Neda full_name: Vishlaghi, Neda last_name: Vishlaghi - first_name: Felix full_name: Turcios, Felix last_name: Turcios - first_name: Jessie E. full_name: Buth, Jessie E. last_name: Buth - first_name: Wen full_name: Gu, Wen last_name: Gu - first_name: Amanda J. full_name: Collier, Amanda J. last_name: Collier - first_name: Osvaldo full_name: Miranda, Osvaldo id: 862A3C56-A8BF-11E9-B4FA-D9E3E5697425 last_name: Miranda orcid: 0000-0001-6618-6889 - first_name: Di full_name: Chen, Di last_name: Chen - first_name: Shan full_name: Sabri, Shan last_name: Sabri - first_name: Amander T. full_name: Clark, Amander T. last_name: Clark - first_name: Kathrin full_name: Plath, Kathrin last_name: Plath - first_name: Heather R. full_name: Christofk, Heather R. last_name: Christofk - first_name: Michael J. full_name: Gandal, Michael J. last_name: Gandal - first_name: Bennett G. full_name: Novitch, Bennett G. last_name: Novitch citation: ama: Watanabe M, Haney JR, Vishlaghi N, et al. TGFβ superfamily signaling regulates the state of human stem cell pluripotency and competency to create telencephalic organoids. bioRxiv. 2019. doi:10.1101/2019.12.13.875773 apa: Watanabe, M., Haney, J. R., Vishlaghi, N., Turcios, F., Buth, J. E., Gu, W., … Novitch, B. G. (2019). TGFβ superfamily signaling regulates the state of human stem cell pluripotency and competency to create telencephalic organoids. bioRxiv. Cold Spring Harbor Laboratory. https://doi.org/10.1101/2019.12.13.875773 chicago: Watanabe, Momoko, Jillian R. Haney, Neda Vishlaghi, Felix Turcios, Jessie E. Buth, Wen Gu, Amanda J. Collier, et al. “TGFβ Superfamily Signaling Regulates the State of Human Stem Cell Pluripotency and Competency to Create Telencephalic Organoids.” BioRxiv. Cold Spring Harbor Laboratory, 2019. https://doi.org/10.1101/2019.12.13.875773. ieee: M. Watanabe et al., “TGFβ superfamily signaling regulates the state of human stem cell pluripotency and competency to create telencephalic organoids,” bioRxiv. Cold Spring Harbor Laboratory, 2019. ista: Watanabe M, Haney JR, Vishlaghi N, Turcios F, Buth JE, Gu W, Collier AJ, Miranda O, Chen D, Sabri S, Clark AT, Plath K, Christofk HR, Gandal MJ, Novitch BG. 2019. TGFβ superfamily signaling regulates the state of human stem cell pluripotency and competency to create telencephalic organoids. bioRxiv, 10.1101/2019.12.13.875773. mla: Watanabe, Momoko, et al. “TGFβ Superfamily Signaling Regulates the State of Human Stem Cell Pluripotency and Competency to Create Telencephalic Organoids.” BioRxiv, Cold Spring Harbor Laboratory, 2019, doi:10.1101/2019.12.13.875773. short: M. Watanabe, J.R. Haney, N. Vishlaghi, F. Turcios, J.E. Buth, W. Gu, A.J. Collier, O. Miranda, D. Chen, S. Sabri, A.T. Clark, K. Plath, H.R. Christofk, M.J. Gandal, B.G. Novitch, BioRxiv (2019). date_created: 2020-01-23T09:53:40Z date_published: 2019-12-13T00:00:00Z date_updated: 2022-06-17T08:03:32Z day: '13' doi: 10.1101/2019.12.13.875773 extern: '1' language: - iso: eng main_file_link: - open_access: '1' url: https://doi.org/10.1101/2019.12.13.875773 month: '12' oa: 1 oa_version: Preprint page: '75' publication: bioRxiv publication_status: published publisher: Cold Spring Harbor Laboratory status: public title: TGFβ superfamily signaling regulates the state of human stem cell pluripotency and competency to create telencephalic organoids type: preprint user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87 year: '2019' ... --- _id: '7401' abstract: - lang: eng text: 'The genus g(G) of a graph G is the minimum g such that G has an embedding on the orientable surface M_g of genus g. A drawing of a graph on a surface is independently even if every pair of nonadjacent edges in the drawing crosses an even number of times. The Z_2-genus of a graph G, denoted by g_0(G), is the minimum g such that G has an independently even drawing on M_g. By a result of Battle, Harary, Kodama and Youngs from 1962, the graph genus is additive over 2-connected blocks. In 2013, Schaefer and Stefankovic proved that the Z_2-genus of a graph is additive over 2-connected blocks as well, and asked whether this result can be extended to so-called 2-amalgamations, as an analogue of results by Decker, Glover, Huneke, and Stahl for the genus. We give the following partial answer. If G=G_1 cup G_2, G_1 and G_2 intersect in two vertices u and v, and G-u-v has k connected components (among which we count the edge uv if present), then |g_0(G)-(g_0(G_1)+g_0(G_2))|<=k+1. For complete bipartite graphs K_{m,n}, with n >= m >= 3, we prove that g_0(K_{m,n})/g(K_{m,n})=1-O(1/n). Similar results are proved also for the Euler Z_2-genus. We express the Z_2-genus of a graph using the minimum rank of partial symmetric matrices over Z_2; a problem that might be of independent interest. ' alternative_title: - LIPIcs article_number: '39' article_processing_charge: No author: - first_name: Radoslav full_name: Fulek, Radoslav id: 39F3FFE4-F248-11E8-B48F-1D18A9856A87 last_name: Fulek orcid: 0000-0001-8485-1774 - first_name: Jan full_name: Kyncl, Jan last_name: Kyncl citation: ama: 'Fulek R, Kyncl J. Z_2-Genus of graphs and minimum rank of partial symmetric matrices. In: 35th International Symposium on Computational Geometry (SoCG 2019). Vol 129. Schloss Dagstuhl - Leibniz-Zentrum für Informatik; 2019. doi:10.4230/LIPICS.SOCG.2019.39' apa: 'Fulek, R., & Kyncl, J. (2019). Z_2-Genus of graphs and minimum rank of partial symmetric matrices. In 35th International Symposium on Computational Geometry (SoCG 2019) (Vol. 129). Portland, OR, United States: Schloss Dagstuhl - Leibniz-Zentrum für Informatik. https://doi.org/10.4230/LIPICS.SOCG.2019.39' chicago: Fulek, Radoslav, and Jan Kyncl. “Z_2-Genus of Graphs and Minimum Rank of Partial Symmetric Matrices.” In 35th International Symposium on Computational Geometry (SoCG 2019), Vol. 129. Schloss Dagstuhl - Leibniz-Zentrum für Informatik, 2019. https://doi.org/10.4230/LIPICS.SOCG.2019.39. ieee: R. Fulek and J. Kyncl, “Z_2-Genus of graphs and minimum rank of partial symmetric matrices,” in 35th International Symposium on Computational Geometry (SoCG 2019), Portland, OR, United States, 2019, vol. 129. ista: 'Fulek R, Kyncl J. 2019. Z_2-Genus of graphs and minimum rank of partial symmetric matrices. 35th International Symposium on Computational Geometry (SoCG 2019). SoCG: Symposium on Computational Geometry, LIPIcs, vol. 129, 39.' mla: Fulek, Radoslav, and Jan Kyncl. “Z_2-Genus of Graphs and Minimum Rank of Partial Symmetric Matrices.” 35th International Symposium on Computational Geometry (SoCG 2019), vol. 129, 39, Schloss Dagstuhl - Leibniz-Zentrum für Informatik, 2019, doi:10.4230/LIPICS.SOCG.2019.39. short: R. Fulek, J. Kyncl, in:, 35th International Symposium on Computational Geometry (SoCG 2019), Schloss Dagstuhl - Leibniz-Zentrum für Informatik, 2019. conference: end_date: 2019-06-21 location: Portland, OR, United States name: 'SoCG: Symposium on Computational Geometry' start_date: 2019-06-18 date_created: 2020-01-29T16:17:05Z date_published: 2019-06-01T00:00:00Z date_updated: 2021-01-12T08:13:24Z day: '01' ddc: - '000' department: - _id: UlWa doi: 10.4230/LIPICS.SOCG.2019.39 external_id: arxiv: - '1903.08637' file: - access_level: open_access checksum: aac37b09118cc0ab58cf77129e691f8c content_type: application/pdf creator: dernst date_created: 2020-02-04T09:14:31Z date_updated: 2020-07-14T12:47:57Z file_id: '7445' file_name: 2019_LIPIcs_Fulek.pdf file_size: 628347 relation: main_file file_date_updated: 2020-07-14T12:47:57Z has_accepted_license: '1' intvolume: ' 129' language: - iso: eng license: https://creativecommons.org/licenses/by/4.0/ month: '06' oa: 1 oa_version: Published Version project: - _id: 261FA626-B435-11E9-9278-68D0E5697425 call_identifier: FWF grant_number: M02281 name: Eliminating intersections in drawings of graphs publication: 35th International Symposium on Computational Geometry (SoCG 2019) publication_identifier: isbn: - 978-3-95977-104-7 issn: - 1868-8969 publication_status: published publisher: Schloss Dagstuhl - Leibniz-Zentrum für Informatik quality_controlled: '1' scopus_import: 1 status: public title: Z_2-Genus of graphs and minimum rank of partial symmetric matrices tmp: image: /images/cc_by.png legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0) short: CC BY (4.0) type: conference user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87 volume: 129 year: '2019' ... --- _id: '7453' abstract: - lang: eng text: We illustrate the ingredients of the state-of-the-art of model-based approach for the formal design and verification of cyber-physical systems. To capture the interaction between a discrete controller and its continuously evolving environment, we use the formal models of timed and hybrid automata. We explain the steps of modeling and verification in the tools Uppaal and SpaceEx using a case study based on a dual-chamber implantable pacemaker monitoring a human heart. We show how to design a model as a composition of components, how to construct models at varying levels of detail, how to establish that one model is an abstraction of another, how to specify correctness requirements using temporal logic, and how to verify that a model satisfies a logical requirement. acknowledgement: This research was supported in part by the Austrian Science Fund (FWF) under grants S11402-N23(RiSE/SHiNE) and Z211-N23 (Wittgenstein Award). This research has received funding from the Sino-Danish Basic Research Centre, IDEA4CPS, funded by the Danish National Research Foundation and the National Science Foundation, China, the Innovation Fund Denmark centre DiCyPS, as well as the ERC Advanced Grant LASSO. alternative_title: - Lecture Notes in Computer Science article_processing_charge: No author: - first_name: Rajeev full_name: Alur, Rajeev last_name: Alur - first_name: Mirco full_name: Giacobbe, Mirco id: 3444EA5E-F248-11E8-B48F-1D18A9856A87 last_name: Giacobbe orcid: 0000-0001-8180-0904 - first_name: Thomas A full_name: Henzinger, Thomas A id: 40876CD8-F248-11E8-B48F-1D18A9856A87 last_name: Henzinger orcid: 0000−0002−2985−7724 - first_name: Kim G. full_name: Larsen, Kim G. last_name: Larsen - first_name: Marius full_name: Mikučionis, Marius last_name: Mikučionis citation: ama: 'Alur R, Giacobbe M, Henzinger TA, Larsen KG, Mikučionis M. Continuous-time models for system design and analysis. In: Steffen B, Woeginger G, eds. Computing and Software Science. Vol 10000. LNCS. Springer Nature; 2019:452-477. doi:10.1007/978-3-319-91908-9_22' apa: Alur, R., Giacobbe, M., Henzinger, T. A., Larsen, K. G., & Mikučionis, M. (2019). Continuous-time models for system design and analysis. In B. Steffen & G. Woeginger (Eds.), Computing and Software Science (Vol. 10000, pp. 452–477). Springer Nature. https://doi.org/10.1007/978-3-319-91908-9_22 chicago: Alur, Rajeev, Mirco Giacobbe, Thomas A Henzinger, Kim G. Larsen, and Marius Mikučionis. “Continuous-Time Models for System Design and Analysis.” In Computing and Software Science, edited by Bernhard Steffen and Gerhard Woeginger, 10000:452–77. LNCS. Springer Nature, 2019. https://doi.org/10.1007/978-3-319-91908-9_22. ieee: R. Alur, M. Giacobbe, T. A. Henzinger, K. G. Larsen, and M. Mikučionis, “Continuous-time models for system design and analysis,” in Computing and Software Science, vol. 10000, B. Steffen and G. Woeginger, Eds. Springer Nature, 2019, pp. 452–477. ista: 'Alur R, Giacobbe M, Henzinger TA, Larsen KG, Mikučionis M. 2019.Continuous-time models for system design and analysis. In: Computing and Software Science. Lecture Notes in Computer Science, vol. 10000, 452–477.' mla: Alur, Rajeev, et al. “Continuous-Time Models for System Design and Analysis.” Computing and Software Science, edited by Bernhard Steffen and Gerhard Woeginger, vol. 10000, Springer Nature, 2019, pp. 452–77, doi:10.1007/978-3-319-91908-9_22. short: R. Alur, M. Giacobbe, T.A. Henzinger, K.G. Larsen, M. Mikučionis, in:, B. Steffen, G. Woeginger (Eds.), Computing and Software Science, Springer Nature, 2019, pp. 452–477. date_created: 2020-02-05T10:51:44Z date_published: 2019-10-05T00:00:00Z date_updated: 2022-09-06T08:25:52Z day: '05' department: - _id: ToHe doi: 10.1007/978-3-319-91908-9_22 editor: - first_name: Bernhard full_name: Steffen, Bernhard last_name: Steffen - first_name: Gerhard full_name: Woeginger, Gerhard last_name: Woeginger intvolume: ' 10000' language: - iso: eng main_file_link: - open_access: '1' url: https://doi.org/10.1007/978-3-319-91908-9_22 month: '10' oa: 1 oa_version: Published Version page: 452-477 project: - _id: 25F2ACDE-B435-11E9-9278-68D0E5697425 call_identifier: FWF grant_number: S11402-N23 name: Rigorous Systems Engineering - _id: 25F42A32-B435-11E9-9278-68D0E5697425 call_identifier: FWF grant_number: Z211 name: The Wittgenstein Prize publication: Computing and Software Science publication_identifier: eisbn: - '9783319919089' eissn: - 0302-9743 isbn: - '9783319919072' issn: - 1611-3349 publication_status: published publisher: Springer Nature quality_controlled: '1' scopus_import: '1' series_title: LNCS status: public title: Continuous-time models for system design and analysis type: book_chapter user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87 volume: 10000 year: '2019' ... --- _id: '7459' abstract: - lang: eng text: We report the fabrication of BaTiO3-Ni magnetoelectric nanocomposites comprising of BaTiO3 nanotubes surrounded by Ni matrix. BaTiO3 nanotubes obtained from the hydrothermal transformation of TiO2 have both inner and outer surfaces, which facilitates greater magnetoelectric coupling with the surrounding Ni matrix. The magnetoelectric coupling was studied by measuring the piezoelectric behavior in the presence of an in-plane direct magnetic field. A higher magnetoelectric voltage coefficient of 110 mV/cm·Oe was obtained, because of better coupling between Ni and BaTiO3 through the walls of the nanotubes. Such nanocomposite developed directly on Ti substrate may lead to efficient fabrication of magnetoelectric devices. article_processing_charge: No article_type: original author: - first_name: Samba Siva full_name: Vadla, Samba Siva last_name: Vadla - first_name: Tommaso full_name: Costanzo, Tommaso id: D93824F4-D9BA-11E9-BB12-F207E6697425 last_name: Costanzo orcid: 0000-0001-9732-3815 - first_name: Subish full_name: John, Subish last_name: John - first_name: Gabriel full_name: Caruntu, Gabriel last_name: Caruntu - first_name: Somnath C. full_name: Roy, Somnath C. last_name: Roy citation: ama: Vadla SS, Costanzo T, John S, Caruntu G, Roy SC. Local probing of magnetoelectric coupling in BaTiO3-Ni 1–3 composites. Scripta Materialia. 2019;159:33-36. doi:10.1016/j.scriptamat.2018.09.003 apa: Vadla, S. S., Costanzo, T., John, S., Caruntu, G., & Roy, S. C. (2019). Local probing of magnetoelectric coupling in BaTiO3-Ni 1–3 composites. Scripta Materialia. Elsevier. https://doi.org/10.1016/j.scriptamat.2018.09.003 chicago: Vadla, Samba Siva, Tommaso Costanzo, Subish John, Gabriel Caruntu, and Somnath C. Roy. “Local Probing of Magnetoelectric Coupling in BaTiO3-Ni 1–3 Composites.” Scripta Materialia. Elsevier, 2019. https://doi.org/10.1016/j.scriptamat.2018.09.003. ieee: S. S. Vadla, T. Costanzo, S. John, G. Caruntu, and S. C. Roy, “Local probing of magnetoelectric coupling in BaTiO3-Ni 1–3 composites,” Scripta Materialia, vol. 159. Elsevier, pp. 33–36, 2019. ista: Vadla SS, Costanzo T, John S, Caruntu G, Roy SC. 2019. Local probing of magnetoelectric coupling in BaTiO3-Ni 1–3 composites. Scripta Materialia. 159, 33–36. mla: Vadla, Samba Siva, et al. “Local Probing of Magnetoelectric Coupling in BaTiO3-Ni 1–3 Composites.” Scripta Materialia, vol. 159, Elsevier, 2019, pp. 33–36, doi:10.1016/j.scriptamat.2018.09.003. short: S.S. Vadla, T. Costanzo, S. John, G. Caruntu, S.C. Roy, Scripta Materialia 159 (2019) 33–36. date_created: 2020-02-05T14:19:17Z date_published: 2019-01-15T00:00:00Z date_updated: 2023-02-23T13:08:31Z day: '15' doi: 10.1016/j.scriptamat.2018.09.003 extern: '1' intvolume: ' 159' language: - iso: eng month: '01' oa_version: None page: 33-36 publication: Scripta Materialia publication_identifier: issn: - 1359-6462 publication_status: published publisher: Elsevier quality_controlled: '1' status: public title: Local probing of magnetoelectric coupling in BaTiO3-Ni 1–3 composites type: journal_article user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87 volume: 159 year: '2019' ...