---
_id: '1442'
abstract:
- lang: eng
text: We give a cohomological interpretation of both the Kac polynomial and the
refined Donaldson-Thomas-invariants of quivers. This interpretation yields a proof
of a conjecture of Kac from 1982 and gives a new perspective on recent work of
Kontsevich-Soibelman. Thisis achieved by computing, via an arithmetic Fourier
transform, the dimensions of the isotypical components of the cohomology of associated
Nakajima quiver varieties under the action of a Weyl group. The generating function
of the corresponding Poincare polynomials is an extension of Hua's formula for
Kac polynomials of quivers involving Hall-Littlewood symmetric functions. The
resulting formulae contain a wide range of information on the geometry of the
quiver varieties.
acknowledgement: |-
The first author thanks the Royal Society for funding his research 2005-2012 in the form of a Royal Society University Research Fellowship as well as the Mathematical Institute and Wadham College in Oxford for a very productive environment. The second author is supported by Agence Nationale de la Recherche grant
ANR-09-JCJC-0102-01. The third author is supported by the NSF grant DMS-1101484 and a Research Scholarship from the Clay Mathematical Institute.
author:
- first_name: Tamas
full_name: Tamas Hausel
id: 4A0666D8-F248-11E8-B48F-1D18A9856A87
last_name: Hausel
- first_name: Emmanuel
full_name: Letellier, Emmanuel
last_name: Letellier
- first_name: Fernando
full_name: Rodríguez Villegas, Fernando
last_name: Rodríguez Villegas
citation:
ama: Hausel T, Letellier E, Rodríguez Villegas F. Positivity for Kac polynomials
and DT-invariants of quivers. Annals of Mathematics. 2013;177(3):1147-1168.
doi:10.4007/annals.2013.177.3.8
apa: Hausel, T., Letellier, E., & Rodríguez Villegas, F. (2013). Positivity
for Kac polynomials and DT-invariants of quivers. Annals of Mathematics.
Princeton University Press. https://doi.org/10.4007/annals.2013.177.3.8
chicago: Hausel, Tamás, Emmanuel Letellier, and Fernando Rodríguez Villegas. “Positivity
for Kac Polynomials and DT-Invariants of Quivers.” Annals of Mathematics.
Princeton University Press, 2013. https://doi.org/10.4007/annals.2013.177.3.8.
ieee: T. Hausel, E. Letellier, and F. Rodríguez Villegas, “Positivity for Kac polynomials
and DT-invariants of quivers,” Annals of Mathematics, vol. 177, no. 3.
Princeton University Press, pp. 1147–1168, 2013.
ista: Hausel T, Letellier E, Rodríguez Villegas F. 2013. Positivity for Kac polynomials
and DT-invariants of quivers. Annals of Mathematics. 177(3), 1147–1168.
mla: Hausel, Tamás, et al. “Positivity for Kac Polynomials and DT-Invariants of
Quivers.” Annals of Mathematics, vol. 177, no. 3, Princeton University
Press, 2013, pp. 1147–68, doi:10.4007/annals.2013.177.3.8.
short: T. Hausel, E. Letellier, F. Rodríguez Villegas, Annals of Mathematics 177
(2013) 1147–1168.
date_created: 2018-12-11T11:52:02Z
date_published: 2013-01-01T00:00:00Z
date_updated: 2021-01-12T06:50:47Z
day: '01'
doi: 10.4007/annals.2013.177.3.8
extern: 1
intvolume: ' 177'
issue: '3'
main_file_link:
- open_access: '1'
url: http://arxiv.org/abs/1204.2375
month: '01'
oa: 1
page: 1147 - 1168
publication: Annals of Mathematics
publication_status: published
publisher: Princeton University Press
publist_id: '5754'
quality_controlled: 0
status: public
title: Positivity for Kac polynomials and DT-invariants of quivers
type: journal_article
volume: 177
year: '2013'
...
---
_id: '1443'
abstract:
- lang: eng
text: 'Here we survey several results and conjectures on the cohomology of the total
space of the Hitchin system: the moduli space of semi-stable rank n and degree
d Higgs bundles on a complex algebraic curve C. The picture emerging is a dynamic
mixture of ideas originating in theoretical physics such as gauge theory and mirror
symmetry, Weil conjectures in arithmetic algebraic geometry, representation theory
of finite groups of Lie type and Langlands duality in number theory.'
alternative_title:
- Advanced Lectures in Mathematics
author:
- first_name: Tamas
full_name: Tamas Hausel
id: 4A0666D8-F248-11E8-B48F-1D18A9856A87
last_name: Hausel
citation:
ama: 'Hausel T. Global topology of the Hitchin system. In: Handbook of Moduli:
Volume II. Vol 25. International Press; 2013:29-70.'
apa: 'Hausel, T. (2013). Global topology of the Hitchin system. In Handbook of
Moduli: Volume II (Vol. 25, pp. 29–70). International Press.'
chicago: 'Hausel, Tamás. “Global Topology of the Hitchin System.” In Handbook
of Moduli: Volume II, 25:29–70. International Press, 2013.'
ieee: 'T. Hausel, “Global topology of the Hitchin system,” in Handbook of Moduli:
Volume II, vol. 25, International Press, 2013, pp. 29–70.'
ista: 'Hausel T. 2013.Global topology of the Hitchin system. In: Handbook of Moduli:
Volume II. Advanced Lectures in Mathematics, vol. 25, 29–70.'
mla: 'Hausel, Tamás. “Global Topology of the Hitchin System.” Handbook of Moduli:
Volume II, vol. 25, International Press, 2013, pp. 29–70.'
short: 'T. Hausel, in:, Handbook of Moduli: Volume II, International Press, 2013,
pp. 29–70.'
date_created: 2018-12-11T11:52:03Z
date_published: 2013-03-15T00:00:00Z
date_updated: 2021-01-12T06:50:47Z
day: '15'
extern: 1
intvolume: ' 25'
main_file_link:
- open_access: '1'
url: http://arxiv.org/abs/1102.1717
month: '03'
oa: 1
page: 29 - 70
publication: 'Handbook of Moduli: Volume II'
publication_status: published
publisher: International Press
publist_id: '5753'
quality_controlled: 0
status: public
title: Global topology of the Hitchin system
type: book_chapter
volume: 25
year: '2013'
...
---
_id: '1469'
abstract:
- lang: eng
text: We study connections between the topology of generic character varieties of
fundamental groups of punctured Riemann surfaces, Macdonald polynomials, quiver
representations, Hilbert schemes on Cx × Cx, modular forms and multiplicities
in tensor products of irreducible characters of finite general linear groups.
acknowledgement: During the preparation of this paper TH was supported by a Royal
Society University Research Fellowship at the University of Oxford. EL was supported
by ANR-09-JCJC-0102-01. FRV was supported by NSF grant DMS-0200605, an FRA from
the University of Texas at Austin, EPSRC grant EP/G027110/1, Visiting Fellowships
at All Souls and Wadham Colleges in Oxford and a Research Scholarship from the Clay
Mathematical Institute.
author:
- first_name: Tamas
full_name: Tamas Hausel
id: 4A0666D8-F248-11E8-B48F-1D18A9856A87
last_name: Hausel
- first_name: Emmanuel
full_name: Letellier, Emmanuel
last_name: Letellier
- first_name: Fernando
full_name: Rodríguez Villegas, Fernando
last_name: Rodríguez Villegas
citation:
ama: Hausel T, Letellier E, Rodríguez Villegas F. Arithmetic harmonic analysis on
character and quiver varieties II. Advances in Mathematics. 2013;234:85-128.
doi:10.1016/j.aim.2012.10.009
apa: Hausel, T., Letellier, E., & Rodríguez Villegas, F. (2013). Arithmetic
harmonic analysis on character and quiver varieties II. Advances in Mathematics.
Academic Press. https://doi.org/10.1016/j.aim.2012.10.009
chicago: Hausel, Tamás, Emmanuel Letellier, and Fernando Rodríguez Villegas. “Arithmetic
Harmonic Analysis on Character and Quiver Varieties II.” Advances in Mathematics.
Academic Press, 2013. https://doi.org/10.1016/j.aim.2012.10.009.
ieee: T. Hausel, E. Letellier, and F. Rodríguez Villegas, “Arithmetic harmonic analysis
on character and quiver varieties II,” Advances in Mathematics, vol. 234.
Academic Press, pp. 85–128, 2013.
ista: Hausel T, Letellier E, Rodríguez Villegas F. 2013. Arithmetic harmonic analysis
on character and quiver varieties II. Advances in Mathematics. 234, 85–128.
mla: Hausel, Tamás, et al. “Arithmetic Harmonic Analysis on Character and Quiver
Varieties II.” Advances in Mathematics, vol. 234, Academic Press, 2013,
pp. 85–128, doi:10.1016/j.aim.2012.10.009.
short: T. Hausel, E. Letellier, F. Rodríguez Villegas, Advances in Mathematics 234
(2013) 85–128.
date_created: 2018-12-11T11:52:12Z
date_published: 2013-02-15T00:00:00Z
date_updated: 2021-01-12T06:50:57Z
day: '15'
doi: 10.1016/j.aim.2012.10.009
extern: 1
intvolume: ' 234'
month: '02'
page: 85 - 128
publication: Advances in Mathematics
publication_status: published
publisher: Academic Press
publist_id: '5724'
quality_controlled: 0
status: public
title: Arithmetic harmonic analysis on character and quiver varieties II
type: journal_article
volume: 234
year: '2013'
...
---
_id: '1470'
abstract:
- lang: eng
text: We show that a natural isomorphism between the rational cohomology groups
of the two zero-dimensional Hilbert schemes of n-points of two surfaces, the affine
plane minus the axes and the cotangent bundle of an elliptic curve, exchanges
the weight filtration on the first set of cohomology groups with the perverse
Leray filtration associated with a natural fibration on the second set of cohomology
groups. We discuss some associated hard Lefschetz phenomena.
acknowledgement: Mark Andrea A. de Cataldo was partially supported by N.S.A. and N.S.F.
Tamás Hausel was supported by a Royal Society University Research Fellowship. Luca
Migliorini was partially supported by PRIN 2007 project "Spazi di moduli e teoria
di Lie"
author:
- first_name: Mark
full_name: De Cataldo, Mark A
last_name: De Cataldo
- first_name: Tamas
full_name: Tamas Hausel
id: 4A0666D8-F248-11E8-B48F-1D18A9856A87
last_name: Hausel
- first_name: Luca
full_name: Migliorini, Luca
last_name: Migliorini
citation:
ama: De Cataldo M, Hausel T, Migliorini L. Exchange between perverse and weight
filtration for the Hilbert schemes of points of two surfaces. Journal of Singularities.
2013;7:23-38. doi:10.5427/jsing.2013.7c
apa: De Cataldo, M., Hausel, T., & Migliorini, L. (2013). Exchange between perverse
and weight filtration for the Hilbert schemes of points of two surfaces. Journal
of Singularities. Worldwide Center of Mathematics. https://doi.org/10.5427/jsing.2013.7c
chicago: De Cataldo, Mark, Tamás Hausel, and Luca Migliorini. “Exchange between
Perverse and Weight Filtration for the Hilbert Schemes of Points of Two Surfaces.”
Journal of Singularities. Worldwide Center of Mathematics, 2013. https://doi.org/10.5427/jsing.2013.7c.
ieee: M. De Cataldo, T. Hausel, and L. Migliorini, “Exchange between perverse and
weight filtration for the Hilbert schemes of points of two surfaces,” Journal
of Singularities, vol. 7. Worldwide Center of Mathematics, pp. 23–38, 2013.
ista: De Cataldo M, Hausel T, Migliorini L. 2013. Exchange between perverse and
weight filtration for the Hilbert schemes of points of two surfaces. Journal of
Singularities. 7, 23–38.
mla: De Cataldo, Mark, et al. “Exchange between Perverse and Weight Filtration for
the Hilbert Schemes of Points of Two Surfaces.” Journal of Singularities,
vol. 7, Worldwide Center of Mathematics, 2013, pp. 23–38, doi:10.5427/jsing.2013.7c.
short: M. De Cataldo, T. Hausel, L. Migliorini, Journal of Singularities 7 (2013)
23–38.
date_created: 2018-12-11T11:52:12Z
date_published: 2013-01-01T00:00:00Z
date_updated: 2021-01-12T06:50:58Z
day: '01'
doi: 10.5427/jsing.2013.7c
extern: 1
intvolume: ' 7'
main_file_link:
- open_access: '1'
url: http://arxiv.org/abs/1012.2583
month: '01'
oa: 1
page: 23 - 38
publication: Journal of Singularities
publication_status: published
publisher: Worldwide Center of Mathematics
publist_id: '5725'
quality_controlled: 0
status: public
title: Exchange between perverse and weight filtration for the Hilbert schemes of
points of two surfaces
type: journal_article
volume: 7
year: '2013'
...
---
_id: '11758'
article_processing_charge: No
article_type: letter_note
author:
- first_name: Luca
full_name: Aceto, Luca
last_name: Aceto
- first_name: Monika H
full_name: Henzinger, Monika H
id: 540c9bbd-f2de-11ec-812d-d04a5be85630
last_name: Henzinger
orcid: 0000-0002-5008-6530
- first_name: Jiří
full_name: Sgall, Jiří
last_name: Sgall
citation:
ama: Aceto L, Henzinger MH, Sgall J. 38th International Colloquium on Automata,
Languages and Programming. Information and Computation. 2013;222(1):1.
doi:10.1016/j.ic.2012.11.002
apa: Aceto, L., Henzinger, M. H., & Sgall, J. (2013). 38th International Colloquium
on Automata, Languages and Programming. Information and Computation. Elsevier.
https://doi.org/10.1016/j.ic.2012.11.002
chicago: Aceto, Luca, Monika H Henzinger, and Jiří Sgall. “38th International Colloquium
on Automata, Languages and Programming.” Information and Computation. Elsevier,
2013. https://doi.org/10.1016/j.ic.2012.11.002.
ieee: L. Aceto, M. H. Henzinger, and J. Sgall, “38th International Colloquium on
Automata, Languages and Programming,” Information and Computation, vol.
222, no. 1. Elsevier, p. 1, 2013.
ista: Aceto L, Henzinger MH, Sgall J. 2013. 38th International Colloquium on Automata,
Languages and Programming. Information and Computation. 222(1), 1.
mla: Aceto, Luca, et al. “38th International Colloquium on Automata, Languages and
Programming.” Information and Computation, vol. 222, no. 1, Elsevier, 2013,
p. 1, doi:10.1016/j.ic.2012.11.002.
short: L. Aceto, M.H. Henzinger, J. Sgall, Information and Computation 222 (2013)
1.
date_created: 2022-08-08T11:25:34Z
date_published: 2013-01-01T00:00:00Z
date_updated: 2023-02-23T10:09:19Z
day: '01'
doi: 10.1016/j.ic.2012.11.002
extern: '1'
intvolume: ' 222'
issue: '1'
language:
- iso: eng
month: '01'
oa_version: None
page: '1'
publication: Information and Computation
publication_identifier:
issn:
- 0890-5401
publication_status: published
publisher: Elsevier
quality_controlled: '1'
scopus_import: '1'
status: public
title: 38th International Colloquium on Automata, Languages and Programming
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 222
year: '2013'
...
---
_id: '1726'
abstract:
- lang: eng
text: The development of a functional tissue requires coordination of the amplification
of progenitors and their differentiation into specific cell types. The molecular
basis for this coordination during myotome ontogeny is not well understood. Dermomytome
progenitors that colonize the myotome first acquire myocyte identity and subsequently
proliferate as Pax7-expressing progenitors before undergoing terminal differentiation.
We show that the dynamics of sonic hedgehog (Shh) signaling is crucial for this
transition in both avian and mouse embryos. Initially, Shh ligand emanating from
notochord/floor plate reaches the dermomyotome, where it both maintains the proliferation
of dermomyotome cells and promotes myogenic differentiation of progenitors that
colonized the myotome. Interfering with Shh signaling at this stage produces small
myotomes and accumulation of Pax7-expressing progenitors. An in vivo reporter
of Shh activity combined with mouse genetics revealed the existence of both activator
and repressor Shh activities operating on distinct subsets of cells during the
epaxial myotomal maturation. In contrast to observations in mice, in avians Shh
promotes the differentiation of both epaxial and hypaxial myotome domains. Subsequently,
myogenic progenitors become refractory to Shh; this is likely to occur at the
level of, or upstream of, smoothened signaling. The end of responsiveness to Shh
coincides with, and is thus likely to enable, the transition into the growth phase
of the myotome.
acknowledgement: This study was supported by grants from the Israel Science Foundation
(ISF) [11/09 to C.K.]; the Association Francaise contre les Myopathies (AFM) [15642
to C.K.]; the German Research Foundation (DFG) [UN 34/27-1 to C.K.]; the UK Medical
Research Council (MRC) [U117560541 to J.B. and A.K.]; Fondation Pour la Recherche
Médicale (FRM) (post-doctoral fellowship to V.R.). Deposited in PMC for release
after 6 months
author:
- first_name: Nitza
full_name: Kahane, Nitza
last_name: Kahane
- first_name: Vanessa
full_name: Ribes, Vanessa
last_name: Ribes
- first_name: Anna
full_name: Anna Kicheva
id: 3959A2A0-F248-11E8-B48F-1D18A9856A87
last_name: Kicheva
orcid: 0000-0003-4509-4998
- first_name: James
full_name: Briscoe, James
last_name: Briscoe
- first_name: Chaya
full_name: Kalcheim, Chaya
last_name: Kalcheim
citation:
ama: Kahane N, Ribes V, Kicheva A, Briscoe J, Kalcheim C. The transition from differentiation
to growth during dermomyotome-derived myogenesis depends on temporally restricted
hedgehog signaling. Development. 2013;140(8):1740-1750. doi:10.1242/dev.092726
apa: Kahane, N., Ribes, V., Kicheva, A., Briscoe, J., & Kalcheim, C. (2013).
The transition from differentiation to growth during dermomyotome-derived myogenesis
depends on temporally restricted hedgehog signaling. Development. Company
of Biologists. https://doi.org/10.1242/dev.092726
chicago: Kahane, Nitza, Vanessa Ribes, Anna Kicheva, James Briscoe, and Chaya Kalcheim.
“The Transition from Differentiation to Growth during Dermomyotome-Derived Myogenesis
Depends on Temporally Restricted Hedgehog Signaling.” Development. Company
of Biologists, 2013. https://doi.org/10.1242/dev.092726.
ieee: N. Kahane, V. Ribes, A. Kicheva, J. Briscoe, and C. Kalcheim, “The transition
from differentiation to growth during dermomyotome-derived myogenesis depends
on temporally restricted hedgehog signaling,” Development, vol. 140, no.
8. Company of Biologists, pp. 1740–1750, 2013.
ista: Kahane N, Ribes V, Kicheva A, Briscoe J, Kalcheim C. 2013. The transition
from differentiation to growth during dermomyotome-derived myogenesis depends
on temporally restricted hedgehog signaling. Development. 140(8), 1740–1750.
mla: Kahane, Nitza, et al. “The Transition from Differentiation to Growth during
Dermomyotome-Derived Myogenesis Depends on Temporally Restricted Hedgehog Signaling.”
Development, vol. 140, no. 8, Company of Biologists, 2013, pp. 1740–50,
doi:10.1242/dev.092726.
short: N. Kahane, V. Ribes, A. Kicheva, J. Briscoe, C. Kalcheim, Development 140
(2013) 1740–1750.
date_created: 2018-12-11T11:53:41Z
date_published: 2013-04-18T00:00:00Z
date_updated: 2021-01-12T06:52:47Z
day: '18'
doi: 10.1242/dev.092726
extern: 1
intvolume: ' 140'
issue: '8'
month: '04'
page: 1740 - 1750
publication: Development
publication_status: published
publisher: Company of Biologists
publist_id: '5402'
quality_controlled: 0
status: public
title: The transition from differentiation to growth during dermomyotome-derived myogenesis
depends on temporally restricted hedgehog signaling
type: journal_article
volume: 140
year: '2013'
...
---
_id: '1727'
abstract:
- lang: eng
text: 'Cells at different positions in a developing tissue receive different concentrations
of signaling molecules, called morphogens, and this influences their cell fate.
Morphogen concentration gradients have been proposed to control patterning as
well as growth in many developing tissues. Some outstanding questions about tissue
patterning by morphogen gradients are the following: What are the mechanisms that
regulate gradient formation and shape? Is the positional information encoded in
the gradient sufficiently precise to determine the positions of target gene domain
boundaries? What are the temporal dynamics of gradients and how do they relate
to patterning and growth? These questions are inherently quantitative in nature
and addressing them requires measuring morphogen concentrations in cells, levels
of downstream signaling activity, and kinetics of morphogen transport. Here we
first present methods for quantifying morphogen gradient shape in which the measurements
can be calibrated to reflect actual morphogen concentrations. We then discuss
using fluorescence recovery after photobleaching to study the kinetics of morphogen
transport at the tissue level. Finally, we present particle tracking as a method
to study morphogen intracellular trafficking.'
author:
- first_name: Anna
full_name: Anna Kicheva
id: 3959A2A0-F248-11E8-B48F-1D18A9856A87
last_name: Kicheva
orcid: 0000-0003-4509-4998
- first_name: Laurent
full_name: Holtzer, Laurent
last_name: Holtzer
- first_name: Ortrud
full_name: Wartlick, Ortrud
last_name: Wartlick
- first_name: Thomas
full_name: Schmidt, Thomas S
last_name: Schmidt
- first_name: Marcos
full_name: González-Gaitán, Marcos A
last_name: González Gaitán
citation:
ama: Kicheva A, Holtzer L, Wartlick O, Schmidt T, González Gaitán M. Quantitative
imaging of morphogen gradients in drosophila imaginal discs. Cold Spring Harbor
Protocols. 2013;8(5):387-403. doi:10.1101/pdb.top074237
apa: Kicheva, A., Holtzer, L., Wartlick, O., Schmidt, T., & González Gaitán,
M. (2013). Quantitative imaging of morphogen gradients in drosophila imaginal
discs. Cold Spring Harbor Protocols. Cold Spring Harbor Laboratory Press.
https://doi.org/10.1101/pdb.top074237
chicago: Kicheva, Anna, Laurent Holtzer, Ortrud Wartlick, Thomas Schmidt, and Marcos
González Gaitán. “Quantitative Imaging of Morphogen Gradients in Drosophila Imaginal
Discs.” Cold Spring Harbor Protocols. Cold Spring Harbor Laboratory Press,
2013. https://doi.org/10.1101/pdb.top074237.
ieee: A. Kicheva, L. Holtzer, O. Wartlick, T. Schmidt, and M. González Gaitán, “Quantitative
imaging of morphogen gradients in drosophila imaginal discs,” Cold Spring Harbor
Protocols, vol. 8, no. 5. Cold Spring Harbor Laboratory Press, pp. 387–403,
2013.
ista: Kicheva A, Holtzer L, Wartlick O, Schmidt T, González Gaitán M. 2013. Quantitative
imaging of morphogen gradients in drosophila imaginal discs. Cold Spring Harbor
Protocols. 8(5), 387–403.
mla: Kicheva, Anna, et al. “Quantitative Imaging of Morphogen Gradients in Drosophila
Imaginal Discs.” Cold Spring Harbor Protocols, vol. 8, no. 5, Cold Spring
Harbor Laboratory Press, 2013, pp. 387–403, doi:10.1101/pdb.top074237.
short: A. Kicheva, L. Holtzer, O. Wartlick, T. Schmidt, M. González Gaitán, Cold
Spring Harbor Protocols 8 (2013) 387–403.
date_created: 2018-12-11T11:53:41Z
date_published: 2013-05-01T00:00:00Z
date_updated: 2021-01-12T06:52:47Z
day: '01'
doi: 10.1101/pdb.top074237
extern: 1
intvolume: ' 8'
issue: '5'
month: '05'
page: 387 - 403
publication: Cold Spring Harbor Protocols
publication_status: published
publisher: Cold Spring Harbor Laboratory Press
publist_id: '5401'
quality_controlled: 0
status: public
title: Quantitative imaging of morphogen gradients in drosophila imaginal discs
type: journal_article
volume: 8
year: '2013'
...
---
_id: '1760'
abstract:
- lang: eng
text: We report on hole g-factor measurements in three terminal SiGe self-assembled
quantum dot devices with a top gate electrode positioned very close to the nanostructure.
Measurements of both the perpendicular as well as the parallel g-factor reveal
significant changes for a small modulation of the top gate voltage. From the observed
modulations, we estimate that, for realistic experimental conditions, hole spins
can be electrically manipulated with Rabi frequencies in the order of 100 MHz.
This work emphasises the potential of hole-based nano-devices for efficient spin
manipulation by means of the g-tensor modulation technique.
acknowledgement: We acknowledge the financial support from the Nanosciences Foundation
(Grenoble, France), the Commission for a Marie Curie Carrer Integration Grant, the
Austrian Science Fund (FWF) for a Lise-Meitner Fellowship (M1435-N30), the DOE under
Contract No. DE-FG02-08ER46482 (Yale), the European Starting Grant program, and
the Agence Nationale de la Recherche
author:
- first_name: Natalia
full_name: Ares, Natalia
last_name: Ares
- first_name: Georgios
full_name: Georgios Katsaros
id: 38DB5788-F248-11E8-B48F-1D18A9856A87
last_name: Katsaros
- first_name: Vitaly
full_name: Golovach, Vitaly N
last_name: Golovach
- first_name: Jianjun
full_name: Zhang, Jianjun
last_name: Zhang
- first_name: Aaron
full_name: Prager, Aaron A
last_name: Prager
- first_name: Leonid
full_name: Glazman, Leonid I
last_name: Glazman
- first_name: Oliver
full_name: Schmidt, Oliver G
last_name: Schmidt
- first_name: Silvano
full_name: De Franceschi, Silvano
last_name: De Franceschi
citation:
ama: Ares N, Katsaros G, Golovach V, et al. SiGe quantum dots for fast hole spin
Rabi oscillations. Applied Physics Letters. 2013;103(26). doi:10.1063/1.4858959
apa: Ares, N., Katsaros, G., Golovach, V., Zhang, J., Prager, A., Glazman, L., …
De Franceschi, S. (2013). SiGe quantum dots for fast hole spin Rabi oscillations.
Applied Physics Letters. American Institute of Physics. https://doi.org/10.1063/1.4858959
chicago: Ares, Natalia, Georgios Katsaros, Vitaly Golovach, Jianjun Zhang, Aaron
Prager, Leonid Glazman, Oliver Schmidt, and Silvano De Franceschi. “SiGe Quantum
Dots for Fast Hole Spin Rabi Oscillations.” Applied Physics Letters. American
Institute of Physics, 2013. https://doi.org/10.1063/1.4858959.
ieee: N. Ares et al., “SiGe quantum dots for fast hole spin Rabi oscillations,”
Applied Physics Letters, vol. 103, no. 26. American Institute of Physics,
2013.
ista: Ares N, Katsaros G, Golovach V, Zhang J, Prager A, Glazman L, Schmidt O, De
Franceschi S. 2013. SiGe quantum dots for fast hole spin Rabi oscillations. Applied
Physics Letters. 103(26).
mla: Ares, Natalia, et al. “SiGe Quantum Dots for Fast Hole Spin Rabi Oscillations.”
Applied Physics Letters, vol. 103, no. 26, American Institute of Physics,
2013, doi:10.1063/1.4858959.
short: N. Ares, G. Katsaros, V. Golovach, J. Zhang, A. Prager, L. Glazman, O. Schmidt,
S. De Franceschi, Applied Physics Letters 103 (2013).
date_created: 2018-12-11T11:53:52Z
date_published: 2013-01-23T00:00:00Z
date_updated: 2021-01-12T06:53:02Z
day: '23'
doi: 10.1063/1.4858959
extern: 1
intvolume: ' 103'
issue: '26'
main_file_link:
- open_access: '1'
url: http://arxiv.org/abs/1307.7196
month: '01'
oa: 1
publication: Applied Physics Letters
publication_status: published
publisher: American Institute of Physics
publist_id: '5364'
quality_controlled: 0
status: public
title: SiGe quantum dots for fast hole spin Rabi oscillations
type: journal_article
volume: 103
year: '2013'
...
---
_id: '1759'
abstract:
- lang: eng
text: We report an electric-field-induced giant modulation of the hole g factor
in SiGe nanocrystals. The observed effect is ascribed to a so-far overlooked contribution
to the g factor that stems from the mixing between heavy- and light-hole wave
functions. We show that the relative displacement between the confined heavy-
and light-hole states, occurring upon application of the electric field, alters
their mixing strength leading to a strong nonmonotonic modulation of the g factor.
acknowledgement: We acknowledge financial support from the Nanosciences Foundation
(Grenoble, France), DOE under Contract No. DEFG02-08ER46482 (Yale), the Agence Nationale
de la Recherche, and the European Starting Grant. G. K. acknowledges support from
the European Commission via a Marie Curie Carrer Integration Grant and the FWF for
a Lise-Meitner Fellowship
author:
- first_name: Natalia
full_name: Ares, Natalia
last_name: Ares
- first_name: Vitaly
full_name: Golovach, Vitaly N
last_name: Golovach
- first_name: Georgios
full_name: Georgios Katsaros
id: 38DB5788-F248-11E8-B48F-1D18A9856A87
last_name: Katsaros
- first_name: Mathieu
full_name: Stoffel, Mathieu
last_name: Stoffel
- first_name: Frank
full_name: Fournel, Frank
last_name: Fournel
- first_name: Leonid
full_name: Glazman, Leonid I
last_name: Glazman
- first_name: Oliver
full_name: Schmidt, Oliver G
last_name: Schmidt
- first_name: Silvano
full_name: De Franceschi, Silvano
last_name: De Franceschi
citation:
ama: Ares N, Golovach V, Katsaros G, et al. Nature of tunable hole g factors in
quantum dots. Physical Review Letters. 2013;110(4). doi:10.1103/PhysRevLett.110.046602
apa: Ares, N., Golovach, V., Katsaros, G., Stoffel, M., Fournel, F., Glazman, L.,
… De Franceschi, S. (2013). Nature of tunable hole g factors in quantum dots.
Physical Review Letters. American Physical Society. https://doi.org/10.1103/PhysRevLett.110.046602
chicago: Ares, Natalia, Vitaly Golovach, Georgios Katsaros, Mathieu Stoffel, Frank
Fournel, Leonid Glazman, Oliver Schmidt, and Silvano De Franceschi. “Nature of
Tunable Hole g Factors in Quantum Dots.” Physical Review Letters. American
Physical Society, 2013. https://doi.org/10.1103/PhysRevLett.110.046602.
ieee: N. Ares et al., “Nature of tunable hole g factors in quantum dots,”
Physical Review Letters, vol. 110, no. 4. American Physical Society, 2013.
ista: Ares N, Golovach V, Katsaros G, Stoffel M, Fournel F, Glazman L, Schmidt O,
De Franceschi S. 2013. Nature of tunable hole g factors in quantum dots. Physical
Review Letters. 110(4).
mla: Ares, Natalia, et al. “Nature of Tunable Hole g Factors in Quantum Dots.” Physical
Review Letters, vol. 110, no. 4, American Physical Society, 2013, doi:10.1103/PhysRevLett.110.046602.
short: N. Ares, V. Golovach, G. Katsaros, M. Stoffel, F. Fournel, L. Glazman, O.
Schmidt, S. De Franceschi, Physical Review Letters 110 (2013).
date_created: 2018-12-11T11:53:51Z
date_published: 2013-01-23T00:00:00Z
date_updated: 2021-01-12T06:53:01Z
day: '23'
doi: 10.1103/PhysRevLett.110.046602
extern: 1
intvolume: ' 110'
issue: '4'
main_file_link:
- open_access: '1'
url: http://arxiv.org/abs/1208.0476
month: '01'
oa: 1
publication: Physical Review Letters
publication_status: published
publisher: American Physical Society
publist_id: '5365'
quality_controlled: 0
status: public
title: Nature of tunable hole g factors in quantum dots
type: journal_article
volume: 110
year: '2013'
...
---
_id: '1785'
abstract:
- lang: eng
text: The geometric aspects of quantum mechanics are emphasized most prominently
by the concept of geometric phases, which are acquired whenever a quantum system
evolves along a path in Hilbert space, that is, the space of quantum states of
the system. The geometric phase is determined only by the shape of this path and
is, in its simplest form, a real number. However, if the system has degenerate
energy levels, then matrix-valued geometric state transformations, known as non-Abelian
holonomies-the effect of which depends on the order of two consecutive paths-can
be obtained. They are important, for example, for the creation of synthetic gauge
fields in cold atomic gases or the description of non-Abelian anyon statistics.
Moreover, there are proposals to exploit non-Abelian holonomic gates for the purposes
of noise-resilient quantum computation. In contrast to Abelian geometric operations,
non-Abelian ones have been observed only in nuclear quadrupole resonance experiments
with a large number of spins, and without full characterization of the geometric
process and its non-commutative nature. Here we realize non-Abelian non-adiabatic
holonomic quantum operations on a single, superconducting, artificial three-level
atom by applying a well-controlled, two-tone microwave drive. Using quantum process
tomography, we determine fidelities of the resulting non-commuting gates that
exceed 95 per cent. We show that two different quantum gates, originating from
two distinct paths in Hilbert space, yield non-equivalent transformations when
applied in different orders. This provides evidence for the non-Abelian character
of the implemented holonomic quantum operations. In combination with a non-trivial
two-quantum-bit gate, our method suggests a way to universal holonomic quantum
computing.
acknowledgement: This work is supported financially by GEOMDISS, the Swiss National
Science Foundation and ETH Zurich
author:
- first_name: Abdufarrukh
full_name: Abdumalikov, Abdufarrukh A
last_name: Abdumalikov
- first_name: Johannes M
full_name: Johannes Fink
id: 4B591CBA-F248-11E8-B48F-1D18A9856A87
last_name: Fink
orcid: 0000-0001-8112-028X
- first_name: K
full_name: Juliusson, K
last_name: Juliusson
- first_name: M
full_name: Pechal, M
last_name: Pechal
- first_name: Stefan
full_name: Berger, Stefan T
last_name: Berger
- first_name: Andreas
full_name: Wallraff, Andreas
last_name: Wallraff
- first_name: Stefan
full_name: Filipp, Stefan
last_name: Filipp
citation:
ama: Abdumalikov A, Fink JM, Juliusson K, et al. Experimental realization of non-Abelian
non-adiabatic geometric gates. Nature. 2013;496(7446):482-485. doi:10.1038/nature12010
apa: Abdumalikov, A., Fink, J. M., Juliusson, K., Pechal, M., Berger, S., Wallraff,
A., & Filipp, S. (2013). Experimental realization of non-Abelian non-adiabatic
geometric gates. Nature. Nature Publishing Group. https://doi.org/10.1038/nature12010
chicago: Abdumalikov, Abdufarrukh, Johannes M Fink, K Juliusson, M Pechal, Stefan
Berger, Andreas Wallraff, and Stefan Filipp. “Experimental Realization of Non-Abelian
Non-Adiabatic Geometric Gates.” Nature. Nature Publishing Group, 2013.
https://doi.org/10.1038/nature12010.
ieee: A. Abdumalikov et al., “Experimental realization of non-Abelian non-adiabatic
geometric gates,” Nature, vol. 496, no. 7446. Nature Publishing Group,
pp. 482–485, 2013.
ista: Abdumalikov A, Fink JM, Juliusson K, Pechal M, Berger S, Wallraff A, Filipp
S. 2013. Experimental realization of non-Abelian non-adiabatic geometric gates.
Nature. 496(7446), 482–485.
mla: Abdumalikov, Abdufarrukh, et al. “Experimental Realization of Non-Abelian Non-Adiabatic
Geometric Gates.” Nature, vol. 496, no. 7446, Nature Publishing Group,
2013, pp. 482–85, doi:10.1038/nature12010.
short: A. Abdumalikov, J.M. Fink, K. Juliusson, M. Pechal, S. Berger, A. Wallraff,
S. Filipp, Nature 496 (2013) 482–485.
date_created: 2018-12-11T11:54:00Z
date_published: 2013-04-25T00:00:00Z
date_updated: 2021-01-12T06:53:11Z
day: '25'
doi: 10.1038/nature12010
extern: 1
intvolume: ' 496'
issue: '7446'
month: '04'
page: 482 - 485
publication: Nature
publication_status: published
publisher: Nature Publishing Group
publist_id: '5329'
quality_controlled: 0
status: public
title: Experimental realization of non-Abelian non-adiabatic geometric gates
type: journal_article
volume: 496
year: '2013'
...
---
_id: '1787'
abstract:
- lang: eng
text: When two indistinguishable single photons impinge at the two inputs of a beam
splitter they coalesce into a pair of photons appearing in either one of its two
outputs. This effect is due to the bosonic nature of photons and was first experimentally
observed by Hong, Ou and Mandel. Here, we present the observation of the Hong-Ou-Mandel
effect with two independent single-photon sources in the microwave frequency domain.
We probe the indistinguishability of single photons, created with a controllable
delay, in time-resolved second-order cross- and auto-correlation function measurements.
Using quadrature amplitude detection we are able to resolve different photon numbers
and detect coherence in and between the output arms. This scheme allows us to
fully characterize the two-mode entanglement of the spatially separated beam-splitter
output modes. Our experiments constitute a first step towards using two-photon
interference at microwave frequencies for quantum communication and information
processing.
acknowledgement: This work was supported by the European Research Council (ERC) through
a Starting Grant and by ETHZ. L.S. was supported by EU IP SOLID. A.B. and M.J.W.
were supported by NSERC, CIFAR and the Alfred P. Sloan Foundation
author:
- first_name: C
full_name: Lang, C
last_name: Lang
- first_name: Christopher
full_name: Eichler, Christopher
last_name: Eichler
- first_name: L.
full_name: Steffen, L. Kraig
last_name: Steffen
- first_name: Johannes M
full_name: Johannes Fink
id: 4B591CBA-F248-11E8-B48F-1D18A9856A87
last_name: Fink
orcid: 0000-0001-8112-028X
- first_name: Matthew
full_name: Woolley, Matthew J
last_name: Woolley
- first_name: Alexandre
full_name: Blais, Alexandre
last_name: Blais
- first_name: Andreas
full_name: Wallraff, Andreas
last_name: Wallraff
citation:
ama: Lang C, Eichler C, Steffen L, et al. Correlations, indistinguishability and
entanglement in Hong-Ou-Mandel experiments at microwave frequencies. Nature
Physics. 2013;9(6):345-348. doi:10.1038/nphys2612
apa: Lang, C., Eichler, C., Steffen, L., Fink, J. M., Woolley, M., Blais, A., &
Wallraff, A. (2013). Correlations, indistinguishability and entanglement in Hong-Ou-Mandel
experiments at microwave frequencies. Nature Physics. Nature Publishing
Group. https://doi.org/10.1038/nphys2612
chicago: Lang, C, Christopher Eichler, L. Steffen, Johannes M Fink, Matthew Woolley,
Alexandre Blais, and Andreas Wallraff. “Correlations, Indistinguishability and
Entanglement in Hong-Ou-Mandel Experiments at Microwave Frequencies.” Nature
Physics. Nature Publishing Group, 2013. https://doi.org/10.1038/nphys2612.
ieee: C. Lang et al., “Correlations, indistinguishability and entanglement
in Hong-Ou-Mandel experiments at microwave frequencies,” Nature Physics,
vol. 9, no. 6. Nature Publishing Group, pp. 345–348, 2013.
ista: Lang C, Eichler C, Steffen L, Fink JM, Woolley M, Blais A, Wallraff A. 2013.
Correlations, indistinguishability and entanglement in Hong-Ou-Mandel experiments
at microwave frequencies. Nature Physics. 9(6), 345–348.
mla: Lang, C., et al. “Correlations, Indistinguishability and Entanglement in Hong-Ou-Mandel
Experiments at Microwave Frequencies.” Nature Physics, vol. 9, no. 6, Nature
Publishing Group, 2013, pp. 345–48, doi:10.1038/nphys2612.
short: C. Lang, C. Eichler, L. Steffen, J.M. Fink, M. Woolley, A. Blais, A. Wallraff,
Nature Physics 9 (2013) 345–348.
date_created: 2018-12-11T11:54:00Z
date_published: 2013-06-01T00:00:00Z
date_updated: 2021-01-12T06:53:11Z
day: '01'
doi: 10.1038/nphys2612
extern: 1
intvolume: ' 9'
issue: '6'
month: '06'
page: 345 - 348
publication: Nature Physics
publication_status: published
publisher: Nature Publishing Group
publist_id: '5327'
quality_controlled: 0
status: public
title: Correlations, indistinguishability and entanglement in Hong-Ou-Mandel experiments
at microwave frequencies
type: journal_article
volume: 9
year: '2013'
...
---
_id: '1786'
abstract:
- lang: eng
text: We report the experimental observation and a theoretical explanation of collective
suppression of linewidths for multiple superconducting qubits coupled to a good
cavity. This demonstrates how strong qubit-cavity coupling can significantly modify
the dephasing and dissipation processes that might be expected for individual
qubits, and can potentially improve coherence times in many-body circuit QED.
acknowledgement: J. K. acknowledges financial support from EPSRC program “TOPNES”
(EP/I031014/1) and EPSRC (EP/G004714/2)
author:
- first_name: Felix
full_name: Nissen, Felix
last_name: Nissen
- first_name: Johannes M
full_name: Johannes Fink
id: 4B591CBA-F248-11E8-B48F-1D18A9856A87
last_name: Fink
orcid: 0000-0001-8112-028X
- first_name: Jonas
full_name: Mlynek, Jonas A
last_name: Mlynek
- first_name: Andreas
full_name: Wallraff, Andreas
last_name: Wallraff
- first_name: Jonathan
full_name: Keeling, Jonathan M
last_name: Keeling
citation:
ama: Nissen F, Fink JM, Mlynek J, Wallraff A, Keeling J. Collective suppression
of linewidths in circuit QED. Physical Review Letters. 2013;110(20). doi:10.1103/PhysRevLett.110.203602
apa: Nissen, F., Fink, J. M., Mlynek, J., Wallraff, A., & Keeling, J. (2013).
Collective suppression of linewidths in circuit QED. Physical Review Letters.
American Physical Society. https://doi.org/10.1103/PhysRevLett.110.203602
chicago: Nissen, Felix, Johannes M Fink, Jonas Mlynek, Andreas Wallraff, and Jonathan
Keeling. “Collective Suppression of Linewidths in Circuit QED.” Physical Review
Letters. American Physical Society, 2013. https://doi.org/10.1103/PhysRevLett.110.203602.
ieee: F. Nissen, J. M. Fink, J. Mlynek, A. Wallraff, and J. Keeling, “Collective
suppression of linewidths in circuit QED,” Physical Review Letters, vol.
110, no. 20. American Physical Society, 2013.
ista: Nissen F, Fink JM, Mlynek J, Wallraff A, Keeling J. 2013. Collective suppression
of linewidths in circuit QED. Physical Review Letters. 110(20).
mla: Nissen, Felix, et al. “Collective Suppression of Linewidths in Circuit QED.”
Physical Review Letters, vol. 110, no. 20, American Physical Society, 2013,
doi:10.1103/PhysRevLett.110.203602.
short: F. Nissen, J.M. Fink, J. Mlynek, A. Wallraff, J. Keeling, Physical Review
Letters 110 (2013).
date_created: 2018-12-11T11:54:00Z
date_published: 2013-05-15T00:00:00Z
date_updated: 2021-01-12T06:53:11Z
day: '15'
doi: 10.1103/PhysRevLett.110.203602
extern: 1
intvolume: ' 110'
issue: '20'
main_file_link:
- open_access: '1'
url: http://arxiv.org/abs/1302.0665
month: '05'
oa: 1
publication: Physical Review Letters
publication_status: published
publisher: American Physical Society
publist_id: '5328'
quality_controlled: 0
status: public
title: Collective suppression of linewidths in circuit QED
type: journal_article
volume: 110
year: '2013'
...
---
_id: '1790'
abstract:
- lang: eng
text: In the September 12, 2013 issue of Nature, the Epi4K Consortium (. Allen etal.,
2013) reported sequencing 264patient trios with epileptic encephalopathies. The
Consortium focused on genes exceptionally intolerant to sequence variations and
found substantial interconnections with autism and intellectual disability gene
networks.
author:
- first_name: Gaia
full_name: Gaia Novarino
id: 3E57A680-F248-11E8-B48F-1D18A9856A87
last_name: Novarino
orcid: 0000-0002-7673-7178
- first_name: Seungtae
full_name: Baek, SeungTae
last_name: Baek
- first_name: Joseph
full_name: Gleeson, Joseph G
last_name: Gleeson
citation:
ama: 'Novarino G, Baek S, Gleeson J. The sacred disease: The puzzling genetics of
epileptic disorders. Neuron. 2013;80(1):9-11. doi:10.1016/j.neuron.2013.09.019'
apa: 'Novarino, G., Baek, S., & Gleeson, J. (2013). The sacred disease: The
puzzling genetics of epileptic disorders. Neuron. Elsevier. https://doi.org/10.1016/j.neuron.2013.09.019'
chicago: 'Novarino, Gaia, Seungtae Baek, and Joseph Gleeson. “The Sacred Disease:
The Puzzling Genetics of Epileptic Disorders.” Neuron. Elsevier, 2013.
https://doi.org/10.1016/j.neuron.2013.09.019.'
ieee: 'G. Novarino, S. Baek, and J. Gleeson, “The sacred disease: The puzzling genetics
of epileptic disorders,” Neuron, vol. 80, no. 1. Elsevier, pp. 9–11, 2013.'
ista: 'Novarino G, Baek S, Gleeson J. 2013. The sacred disease: The puzzling genetics
of epileptic disorders. Neuron. 80(1), 9–11.'
mla: 'Novarino, Gaia, et al. “The Sacred Disease: The Puzzling Genetics of Epileptic
Disorders.” Neuron, vol. 80, no. 1, Elsevier, 2013, pp. 9–11, doi:10.1016/j.neuron.2013.09.019.'
short: G. Novarino, S. Baek, J. Gleeson, Neuron 80 (2013) 9–11.
date_created: 2018-12-11T11:54:01Z
date_published: 2013-10-02T00:00:00Z
date_updated: 2021-01-12T06:53:13Z
day: '02'
doi: 10.1016/j.neuron.2013.09.019
extern: 1
intvolume: ' 80'
issue: '1'
month: '10'
page: 9 - 11
publication: Neuron
publication_status: published
publisher: Elsevier
publist_id: '5323'
quality_controlled: 0
status: public
title: 'The sacred disease: The puzzling genetics of epileptic disorders'
type: journal_article
volume: 80
year: '2013'
...
---
_id: '1977'
abstract:
- lang: eng
text: Complex I (NADH:ubiquinone oxidoreductase) is central to cellular energy production,
being the first and largest enzyme of the respiratory chain in mitochondria. It
couples electron transfer from NADH to ubiquinone with proton translocation across
the inner mitochondrial membrane and is involved in a wide range of human neurodegenerative
disorders. Mammalian complex I is composed of 44 different subunits, whereas the
'minimal' bacterial version contains 14 highly conserved 'core' subunits. The
L-shaped assembly consists of hydrophilic and membrane domains. We have determined
all known atomic structures of complex I, starting from the hydrophilic domain
of Thermus thermophilus enzyme (eight subunits, nine Fe-S clusters), followed
by the membrane domains of the Escherichia coli (six subunits, 55 transmembrane
helices) and T. thermophilus (seven subunits, 64 transmembrane helices) enzymes,
and finally culminating in a recent crystal structure of the entire intact complex
I from T. thermophilus (536 kDa, 16 subunits, nine Fe-S clusters, 64 transmembrane
helices). The structure suggests an unusual and unique coupling mechanism via
longrange conformational changes. Determination of the structure of the entire
complex was possible only through this step-by-step approach, building on from
smaller subcomplexes towards the entire assembly. Large membrane proteins are
notoriously difficult to crystallize, and so various non-standard and sometimes
counterintuitive approaches were employed in order to achieve crystal diffraction
to high resolution and solve the structures. These steps, as well as the implications
from the final structure, are discussed in the present review.
acknowledgement: This work was funded by the Medical Research Council.
author:
- first_name: Leonid A
full_name: Leonid Sazanov
id: 338D39FE-F248-11E8-B48F-1D18A9856A87
last_name: Sazanov
orcid: 0000-0002-0977-7989
- first_name: Rozbeh
full_name: 'Baradaran, Rozbeh '
last_name: Baradaran
- first_name: Rouslan
full_name: Efremov, Rouslan G
last_name: Efremov
- first_name: John
full_name: Berrisford, John M
last_name: Berrisford
- first_name: Gurdeep
full_name: Minhas, Gurdeep S
last_name: Minhas
citation:
ama: Sazanov LA, Baradaran R, Efremov R, Berrisford J, Minhas G. A long road towards
the structure of respiratory complex I, a giant molecular proton pump. Biochemical
Society Transactions. 2013;41(5):1265-1271. doi:10.1042/BST20130193
apa: Sazanov, L. A., Baradaran, R., Efremov, R., Berrisford, J., & Minhas, G.
(2013). A long road towards the structure of respiratory complex I, a giant molecular
proton pump. Biochemical Society Transactions. Portland Press. https://doi.org/10.1042/BST20130193
chicago: Sazanov, Leonid A, Rozbeh Baradaran, Rouslan Efremov, John Berrisford,
and Gurdeep Minhas. “A Long Road towards the Structure of Respiratory Complex
I, a Giant Molecular Proton Pump.” Biochemical Society Transactions. Portland
Press, 2013. https://doi.org/10.1042/BST20130193.
ieee: L. A. Sazanov, R. Baradaran, R. Efremov, J. Berrisford, and G. Minhas, “A
long road towards the structure of respiratory complex I, a giant molecular proton
pump,” Biochemical Society Transactions, vol. 41, no. 5. Portland Press,
pp. 1265–1271, 2013.
ista: Sazanov LA, Baradaran R, Efremov R, Berrisford J, Minhas G. 2013. A long road
towards the structure of respiratory complex I, a giant molecular proton pump.
Biochemical Society Transactions. 41(5), 1265–1271.
mla: Sazanov, Leonid A., et al. “A Long Road towards the Structure of Respiratory
Complex I, a Giant Molecular Proton Pump.” Biochemical Society Transactions,
vol. 41, no. 5, Portland Press, 2013, pp. 1265–71, doi:10.1042/BST20130193.
short: L.A. Sazanov, R. Baradaran, R. Efremov, J. Berrisford, G. Minhas, Biochemical
Society Transactions 41 (2013) 1265–1271.
date_created: 2018-12-11T11:55:00Z
date_published: 2013-10-01T00:00:00Z
date_updated: 2021-01-12T06:54:28Z
day: '01'
doi: 10.1042/BST20130193
extern: 1
intvolume: ' 41'
issue: '5'
month: '10'
page: 1265 - 1271
publication: Biochemical Society Transactions
publication_status: published
publisher: Portland Press
publist_id: '5106'
quality_controlled: 0
status: public
title: A long road towards the structure of respiratory complex I, a giant molecular
proton pump
type: journal_article
volume: 41
year: '2013'
...
---
_id: '1978'
abstract:
- lang: eng
text: Complex I is the first and largest enzyme of the respiratory chain and has
a central role in cellular energy production through the coupling of NADH:ubiquinone
electron transfer to proton translocation. It is also implicated in many common
human neurodegenerative diseases. Here, we report the first crystal structure
of the entire, intact complex I (from Thermus thermophilus) at 3.3 Å resolution.
The structure of the 536-kDa complex comprises 16 different subunits, with a total
of 64 transmembrane helices and 9 iron-sulphur clusters. The core fold of subunit
Nqo8 (ND1 in humans) is, unexpectedly, similar to a half-channel of the antiporter-like
subunits. Small subunits nearby form a linked second half-channel, which completes
the fourth proton-translocation pathway (present in addition to the channels in
three antiporter-like subunits). The quinone-binding site is unusually long, narrow
and enclosed. The quinone headgroup binds at the deep end of this chamber, near
iron-sulphur cluster N2. Notably, the chamber is linked to the fourth channel
by a 'funnel' of charged residues. The link continues over the entire membrane
domain as a flexible central axis of charged and polar residues, and probably
has a leading role in the propagation of conformational changes, aided by coupling
elements. The structure suggests that a unique, out-of-the-membrane quinone-reaction
chamber enables the redox energy to drive concerted long-range conformational
changes in the four antiporter-like domains, resulting in translocation of four
protons per cycle.
acknowledgement: This work was funded by the Medical Research Council.
author:
- first_name: Rozbeh
full_name: 'Baradaran, Rozbeh '
last_name: Baradaran
- first_name: John
full_name: Berrisford, John M
last_name: Berrisford
- first_name: Gurdeep
full_name: Minhas, Gurdeep S
last_name: Minhas
- first_name: Leonid A
full_name: Leonid Sazanov
id: 338D39FE-F248-11E8-B48F-1D18A9856A87
last_name: Sazanov
orcid: 0000-0002-0977-7989
citation:
ama: Baradaran R, Berrisford J, Minhas G, Sazanov LA. Crystal structure of the entire
respiratory complex i. Nature. 2013;494(7438):443-448. doi:10.1038/nature11871
apa: Baradaran, R., Berrisford, J., Minhas, G., & Sazanov, L. A. (2013). Crystal
structure of the entire respiratory complex i. Nature. Nature Publishing
Group. https://doi.org/10.1038/nature11871
chicago: Baradaran, Rozbeh, John Berrisford, Gurdeep Minhas, and Leonid A Sazanov.
“Crystal Structure of the Entire Respiratory Complex I.” Nature. Nature
Publishing Group, 2013. https://doi.org/10.1038/nature11871.
ieee: R. Baradaran, J. Berrisford, G. Minhas, and L. A. Sazanov, “Crystal structure
of the entire respiratory complex i,” Nature, vol. 494, no. 7438. Nature
Publishing Group, pp. 443–448, 2013.
ista: Baradaran R, Berrisford J, Minhas G, Sazanov LA. 2013. Crystal structure of
the entire respiratory complex i. Nature. 494(7438), 443–448.
mla: Baradaran, Rozbeh, et al. “Crystal Structure of the Entire Respiratory Complex
I.” Nature, vol. 494, no. 7438, Nature Publishing Group, 2013, pp. 443–48,
doi:10.1038/nature11871.
short: R. Baradaran, J. Berrisford, G. Minhas, L.A. Sazanov, Nature 494 (2013) 443–448.
date_created: 2018-12-11T11:55:01Z
date_published: 2013-02-28T00:00:00Z
date_updated: 2021-01-12T06:54:28Z
day: '28'
doi: 10.1038/nature11871
extern: 1
intvolume: ' 494'
issue: '7438'
month: '02'
page: 443 - 448
publication: Nature
publication_status: published
publisher: Nature Publishing Group
publist_id: '5107'
quality_controlled: 0
status: public
title: Crystal structure of the entire respiratory complex i
type: journal_article
volume: 494
year: '2013'
...
---
_id: '1991'
abstract:
- lang: eng
text: Although transitions of sex-determination mechanisms are frequent in species
with homomorphic sex chromosomes, heteromorphic sex chromosomes are thought to
represent a terminal evolutionary stage owing to chromosome-specific adaptations
such as dosage compensation or an accumulation of sex-specific mutations. Here
we show that an autosome of Drosophila, the dot chromosome, was ancestrally a
differentiated X chromosome. We analyse the whole genome of true fruitflies (Tephritidae),
flesh flies (Sarcophagidae) and soldier flies (Stratiomyidae) to show that genes
located on the dot chromosome of Drosophila are X-linked in outgroup species,
whereas Drosophila X-linked genes are autosomal. We date this chromosomal transition
to early drosophilid evolution by sequencing the genome of other Drosophilidae.
Our results reveal several puzzling aspects of Drosophila dot chromosome biology
to be possible remnants of its former life as a sex chromosome, such as its minor
feminizing role in sex determination or its targeting by a chromosome-specific
regulatory mechanism. We also show that patterns of biased gene expression of
the dot chromosome during early embryogenesis, oogenesis and spermatogenesis resemble
that of the current X chromosome. Thus, although sex chromosomes are not necessarily
evolutionary end points and can revert back to an autosomal inheritance, the highly
specialized genome architecture of this former X chromosome suggests that severe
fitness costs must be overcome for such a turnover to occur.
acknowledgement: Funded by National Institutes of Health grants (R01GM076007 and R01GM093182)
and a Packard Fellowship to D.B.
author:
- first_name: Beatriz
full_name: Beatriz Vicoso
id: 49E1C5C6-F248-11E8-B48F-1D18A9856A87
last_name: Vicoso
orcid: 0000-0002-4579-8306
- first_name: Doris
full_name: Bachtrog, Doris
last_name: Bachtrog
citation:
ama: Vicoso B, Bachtrog D. Reversal of an ancient sex chromosome to an autosome
in Drosophila. Nature. 2013;499(7458):332-335. doi:10.1038/nature12235
apa: Vicoso, B., & Bachtrog, D. (2013). Reversal of an ancient sex chromosome
to an autosome in Drosophila. Nature. Nature Publishing Group. https://doi.org/10.1038/nature12235
chicago: Vicoso, Beatriz, and Doris Bachtrog. “Reversal of an Ancient Sex Chromosome
to an Autosome in Drosophila.” Nature. Nature Publishing Group, 2013. https://doi.org/10.1038/nature12235.
ieee: B. Vicoso and D. Bachtrog, “Reversal of an ancient sex chromosome to an autosome
in Drosophila,” Nature, vol. 499, no. 7458. Nature Publishing Group, pp.
332–335, 2013.
ista: Vicoso B, Bachtrog D. 2013. Reversal of an ancient sex chromosome to an autosome
in Drosophila. Nature. 499(7458), 332–335.
mla: Vicoso, Beatriz, and Doris Bachtrog. “Reversal of an Ancient Sex Chromosome
to an Autosome in Drosophila.” Nature, vol. 499, no. 7458, Nature Publishing
Group, 2013, pp. 332–35, doi:10.1038/nature12235.
short: B. Vicoso, D. Bachtrog, Nature 499 (2013) 332–335.
date_created: 2018-12-11T11:55:05Z
date_published: 2013-07-18T00:00:00Z
date_updated: 2021-01-12T06:54:33Z
day: '18'
doi: 10.1038/nature12235
extern: 1
intvolume: ' 499'
issue: '7458'
month: '07'
page: 332 - 335
publication: Nature
publication_status: published
publisher: Nature Publishing Group
publist_id: '5092'
quality_controlled: 0
status: public
title: Reversal of an ancient sex chromosome to an autosome in Drosophila
type: journal_article
volume: 499
year: '2013'
...
---
_id: '1988'
abstract:
- lang: eng
text: The rod-shaped bacterium Escherichia coli selects the cell center as site
of division with the help of the proteins MinC, MinD, and MinE. This protein system
collectively oscillates between the two cell poles by alternately binding to the
membrane in one of the two cell halves. This dynamic behavior, which emerges from
the interaction of the ATPase MinD and its activator MinE on the cell membrane,
has become a paradigm for protein self-organization. Recently, it has been found
that not only the binding of MinD to the membrane, but also interactions of MinE
with the membrane contribute to Min-protein self-organization. Here, we show that
by accounting for this finding in a computational model, we can comprehensively
describe all observed Min-protein patterns in vivo and in vitro. Furthermore,
by varying the system's geometry, our computations predict patterns that have
not yet been reported. We confirm these predictions experimentally.
author:
- first_name: Mike
full_name: 'Bonny, Mike '
last_name: Bonny
- first_name: Elisabeth
full_name: Fischer-Friedrich, Elisabeth
last_name: Fischer Friedrich
- first_name: Martin
full_name: Martin Loose
id: 462D4284-F248-11E8-B48F-1D18A9856A87
last_name: Loose
orcid: 0000-0001-7309-9724
- first_name: Petra
full_name: 'Schwille, Petra '
last_name: Schwille
- first_name: Karsten
full_name: Kruse, Karsten
last_name: Kruse
citation:
ama: Bonny M, Fischer Friedrich E, Loose M, Schwille P, Kruse K. Membrane binding
of MinE allows for a comprehensive description of Min-protein pattern formation.
PLoS Computational Biology. 2013;9(12). doi:10.1371/journal.pcbi.1003347
apa: Bonny, M., Fischer Friedrich, E., Loose, M., Schwille, P., & Kruse, K.
(2013). Membrane binding of MinE allows for a comprehensive description of Min-protein
pattern formation. PLoS Computational Biology. Public Library of Science.
https://doi.org/10.1371/journal.pcbi.1003347
chicago: Bonny, Mike, Elisabeth Fischer Friedrich, Martin Loose, Petra Schwille,
and Karsten Kruse. “Membrane Binding of MinE Allows for a Comprehensive Description
of Min-Protein Pattern Formation.” PLoS Computational Biology. Public Library
of Science, 2013. https://doi.org/10.1371/journal.pcbi.1003347.
ieee: M. Bonny, E. Fischer Friedrich, M. Loose, P. Schwille, and K. Kruse, “Membrane
binding of MinE allows for a comprehensive description of Min-protein pattern
formation,” PLoS Computational Biology, vol. 9, no. 12. Public Library
of Science, 2013.
ista: Bonny M, Fischer Friedrich E, Loose M, Schwille P, Kruse K. 2013. Membrane
binding of MinE allows for a comprehensive description of Min-protein pattern
formation. PLoS Computational Biology. 9(12).
mla: Bonny, Mike, et al. “Membrane Binding of MinE Allows for a Comprehensive Description
of Min-Protein Pattern Formation.” PLoS Computational Biology, vol. 9,
no. 12, Public Library of Science, 2013, doi:10.1371/journal.pcbi.1003347.
short: M. Bonny, E. Fischer Friedrich, M. Loose, P. Schwille, K. Kruse, PLoS Computational
Biology 9 (2013).
date_created: 2018-12-11T11:55:04Z
date_published: 2013-12-01T00:00:00Z
date_updated: 2021-01-12T06:54:32Z
day: '01'
doi: 10.1371/journal.pcbi.1003347
extern: 1
intvolume: ' 9'
issue: '12'
month: '12'
publication: PLoS Computational Biology
publication_status: published
publisher: Public Library of Science
publist_id: '5095'
quality_controlled: 0
status: public
title: Membrane binding of MinE allows for a comprehensive description of Min-protein
pattern formation
type: journal_article
volume: 9
year: '2013'
...
---
_id: '2010'
abstract:
- lang: eng
text: Many algorithms for inferring causality rely heavily on the faithfulness assumption.
The main justification for imposing this assumption is that the set of unfaithful
distributions has Lebesgue measure zero, since it can be seen as a collection
of hypersurfaces in a hypercube. However, due to sampling error the faithfulness
condition alone is not sufficient for statistical estimation, and strong-faithfulness
has been proposed and assumed to achieve uniform or high-dimensional consistency.
In contrast to the plain faithfulness assumption, the set of distributions that
is not strong-faithful has nonzero Lebesgue measure and in fact, can be surprisingly
large as we show in this paper. We study the strong-faithfulness condition from
a geometric and combinatorial point of view and give upper and lower bounds on
the Lebesgue measure of strong-faithful distributions for various classes of directed
acyclic graphs. Our results imply fundamental limitations for the PC-algorithm
and potentially also for other algorithms based on partial correlation testing
in the Gaussian case.
author:
- first_name: Caroline
full_name: Uhler, Caroline
id: 49ADD78E-F248-11E8-B48F-1D18A9856A87
last_name: Uhler
orcid: 0000-0002-7008-0216
- first_name: Garvesh
full_name: Raskutti, Garvesh
last_name: Raskutti
- first_name: Peter
full_name: Bühlmann, Peter
last_name: Bühlmann
- first_name: Bin
full_name: Yu, Bin
last_name: Yu
citation:
ama: Uhler C, Raskutti G, Bühlmann P, Yu B. Geometry of the faithfulness assumption
in causal inference. The Annals of Statistics. 2013;41(2):436-463. doi:10.1214/12-AOS1080
apa: Uhler, C., Raskutti, G., Bühlmann, P., & Yu, B. (2013). Geometry of the
faithfulness assumption in causal inference. The Annals of Statistics.
Institute of Mathematical Statistics. https://doi.org/10.1214/12-AOS1080
chicago: Uhler, Caroline, Garvesh Raskutti, Peter Bühlmann, and Bin Yu. “Geometry
of the Faithfulness Assumption in Causal Inference.” The Annals of Statistics.
Institute of Mathematical Statistics, 2013. https://doi.org/10.1214/12-AOS1080.
ieee: C. Uhler, G. Raskutti, P. Bühlmann, and B. Yu, “Geometry of the faithfulness
assumption in causal inference,” The Annals of Statistics, vol. 41, no.
2. Institute of Mathematical Statistics, pp. 436–463, 2013.
ista: Uhler C, Raskutti G, Bühlmann P, Yu B. 2013. Geometry of the faithfulness
assumption in causal inference. The Annals of Statistics. 41(2), 436–463.
mla: Uhler, Caroline, et al. “Geometry of the Faithfulness Assumption in Causal
Inference.” The Annals of Statistics, vol. 41, no. 2, Institute of Mathematical
Statistics, 2013, pp. 436–63, doi:10.1214/12-AOS1080.
short: C. Uhler, G. Raskutti, P. Bühlmann, B. Yu, The Annals of Statistics 41 (2013)
436–463.
date_created: 2018-12-11T11:55:11Z
date_published: 2013-04-01T00:00:00Z
date_updated: 2021-01-12T06:54:42Z
day: '01'
department:
- _id: CaUh
doi: 10.1214/12-AOS1080
external_id:
arxiv:
- '1207.0547'
intvolume: ' 41'
issue: '2'
language:
- iso: eng
main_file_link:
- open_access: '1'
url: www.doi.org/10.1214/12-AOS1080
month: '04'
oa: 1
oa_version: Published Version
page: 436 - 463
publication: The Annals of Statistics
publication_status: published
publisher: Institute of Mathematical Statistics
publist_id: '5066'
quality_controlled: '1'
scopus_import: 1
status: public
title: Geometry of the faithfulness assumption in causal inference
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 41
year: '2013'
...
---
_id: '2009'
abstract:
- lang: eng
text: Traditional statistical methods for confidentiality protection of statistical
databases do not scale well to deal with GWAS databases especially in terms of
guarantees regarding protection from linkage to external information. The more
recent concept of differential privacy, introduced by the cryptographic community,
is an approach which provides a rigorous definition of privacy with meaningful
privacy guarantees in the presence of arbitrary external information, although
the guarantees may come at a serious price in terms of data utility. Building
on such notions, we propose new methods to release aggregate GWAS data without
compromising an individual’s privacy. We present methods for releasing differentially
private minor allele frequencies, chi-square statistics and p-values. We compare
these approaches on simulated data and on a GWAS study of canine hair length involving
685 dogs. We also propose a privacy-preserving method for finding genome-wide
associations based on a differentially-private approach to penalized logistic
regression.
article_processing_charge: No
author:
- first_name: Caroline
full_name: Uhler, Caroline
id: 49ADD78E-F248-11E8-B48F-1D18A9856A87
last_name: Uhler
orcid: 0000-0002-7008-0216
- first_name: Aleksandra
full_name: Slavkovic, Aleksandra
last_name: Slavkovic
- first_name: Stephen
full_name: Fienberg, Stephen
last_name: Fienberg
citation:
ama: Uhler C, Slavkovic A, Fienberg S. Privacy-preserving data sharing for genome-wide
association studies. Journal of Privacy and Confidentiality . 2013;5(1):137-166.
doi:10.29012/jpc.v5i1.629
apa: Uhler, C., Slavkovic, A., & Fienberg, S. (2013). Privacy-preserving data
sharing for genome-wide association studies. Journal of Privacy and Confidentiality
. Carnegie Mellon University. https://doi.org/10.29012/jpc.v5i1.629
chicago: Uhler, Caroline, Aleksandra Slavkovic, and Stephen Fienberg. “Privacy-Preserving
Data Sharing for Genome-Wide Association Studies.” Journal of Privacy and Confidentiality
. Carnegie Mellon University, 2013. https://doi.org/10.29012/jpc.v5i1.629.
ieee: C. Uhler, A. Slavkovic, and S. Fienberg, “Privacy-preserving data sharing
for genome-wide association studies,” Journal of Privacy and Confidentiality
, vol. 5, no. 1. Carnegie Mellon University, pp. 137–166, 2013.
ista: Uhler C, Slavkovic A, Fienberg S. 2013. Privacy-preserving data sharing for
genome-wide association studies. Journal of Privacy and Confidentiality . 5(1),
137–166.
mla: Uhler, Caroline, et al. “Privacy-Preserving Data Sharing for Genome-Wide Association
Studies.” Journal of Privacy and Confidentiality , vol. 5, no. 1, Carnegie
Mellon University, 2013, pp. 137–66, doi:10.29012/jpc.v5i1.629.
short: C. Uhler, A. Slavkovic, S. Fienberg, Journal of Privacy and Confidentiality 5
(2013) 137–166.
date_created: 2018-12-11T11:55:11Z
date_published: 2013-08-01T00:00:00Z
date_updated: 2021-01-12T06:54:41Z
day: '01'
department:
- _id: CaUh
doi: 10.29012/jpc.v5i1.629
intvolume: ' 5'
issue: '1'
language:
- iso: eng
main_file_link:
- open_access: '1'
url: http://repository.cmu.edu/jpc/vol5/iss1/6
month: '08'
oa: 1
oa_version: Published Version
page: 137 - 166
publication: 'Journal of Privacy and Confidentiality '
publication_status: published
publisher: Carnegie Mellon University
publist_id: '5067'
quality_controlled: '1'
status: public
title: Privacy-preserving data sharing for genome-wide association studies
type: journal_article
user_id: 3E5EF7F0-F248-11E8-B48F-1D18A9856A87
volume: 5
year: '2013'
...
---
_id: '2074'
abstract:
- lang: eng
text: 'Sex chromosomes originate from autosomes. The accumulation of sexually antagonistic
mutations on protosex chromosomes selects for a loss of recombination and sets
in motion the evolutionary processes generating heteromorphic sex chromosomes.
Recombination suppression and differentiation are generally viewed as the default
path of sex chromosome evolution, and the occurrence of old, homomorphic sex chromosomes,
such as those of ratite birds, has remained a mystery. Here, we analyze the genome
and transcriptome of emu (Dromaius novaehollandiae) and confirm that most genes
on the sex chromosome are shared between the Z and W. Surprisingly, however, levels
of gene expression are generally sex-biased for all sex-linked genes relative
to autosomes, including those in the pseudoautosomal region, and the male-bias
increases after gonad formation. This expression bias suggests that the emu sex
chromosomes have become masculinized, even in the absence of ZW differentiation.
Thus, birds may have taken different evolutionary solutions to minimize the deleterious
effects imposed by sexually antagonistic mutations: some lineages eliminate recombination
along the protosex chromosomes to physically restrict sexually antagonistic alleles
to one sex, whereas ratites evolved sex-biased expression to confine the product
of a sexually antagonistic allele to the sex it benefits. This difference in conflict
resolution may explain the preservation of recombining, homomorphic sex chromosomes
in other lineages and illustrates the importance of sexually antagonistic mutations
driving the evolution of sex chromosomes. '
author:
- first_name: Beatriz
full_name: Beatriz Vicoso
id: 49E1C5C6-F248-11E8-B48F-1D18A9856A87
last_name: Vicoso
orcid: 0000-0002-4579-8306
- first_name: Vera
full_name: Kaiser, Vera B
last_name: Kaiser
- first_name: Doris
full_name: Bachtrog, Doris
last_name: Bachtrog
citation:
ama: Vicoso B, Kaiser V, Bachtrog D. Sex biased gene expression at homomorphic sex
chromosomes in emus and its implication for sex chromosome evolution. PNAS.
2013;110(16):6453-6458. doi:10.1073/pnas.1217027110
apa: Vicoso, B., Kaiser, V., & Bachtrog, D. (2013). Sex biased gene expression
at homomorphic sex chromosomes in emus and its implication for sex chromosome
evolution. PNAS. National Academy of Sciences. https://doi.org/10.1073/pnas.1217027110
chicago: Vicoso, Beatriz, Vera Kaiser, and Doris Bachtrog. “Sex Biased Gene Expression
at Homomorphic Sex Chromosomes in Emus and Its Implication for Sex Chromosome
Evolution.” PNAS. National Academy of Sciences, 2013. https://doi.org/10.1073/pnas.1217027110.
ieee: B. Vicoso, V. Kaiser, and D. Bachtrog, “Sex biased gene expression at homomorphic
sex chromosomes in emus and its implication for sex chromosome evolution,” PNAS,
vol. 110, no. 16. National Academy of Sciences, pp. 6453–6458, 2013.
ista: Vicoso B, Kaiser V, Bachtrog D. 2013. Sex biased gene expression at homomorphic
sex chromosomes in emus and its implication for sex chromosome evolution. PNAS.
110(16), 6453–6458.
mla: Vicoso, Beatriz, et al. “Sex Biased Gene Expression at Homomorphic Sex Chromosomes
in Emus and Its Implication for Sex Chromosome Evolution.” PNAS, vol. 110,
no. 16, National Academy of Sciences, 2013, pp. 6453–58, doi:10.1073/pnas.1217027110.
short: B. Vicoso, V. Kaiser, D. Bachtrog, PNAS 110 (2013) 6453–6458.
date_created: 2018-12-11T11:55:33Z
date_published: 2013-04-16T00:00:00Z
date_updated: 2021-01-12T06:55:08Z
day: '16'
doi: 10.1073/pnas.1217027110
extern: 1
intvolume: ' 110'
issue: '16'
month: '04'
page: 6453 - 6458
publication: PNAS
publication_status: published
publisher: National Academy of Sciences
publist_id: '4964'
quality_controlled: 0
status: public
title: Sex biased gene expression at homomorphic sex chromosomes in emus and its implication
for sex chromosome evolution
type: journal_article
volume: 110
year: '2013'
...