---
_id: '2264'
abstract:
- lang: eng
text: Faithful progression through the cell cycle is crucial to the maintenance
and developmental potential of stem cells. Here, we demonstrate that neural stem
cells (NSCs) and intermediate neural progenitor cells (NPCs) employ a zinc-finger
transcription factor specificity protein 2 (Sp2) as a cell cycle regulator in
two temporally and spatially distinct progenitor domains. Differential conditional
deletion of Sp2 in early embryonic cerebral cortical progenitors, and perinatal
olfactory bulb progenitors disrupted transitions through G1, G2 and M phases,
whereas DNA synthesis appeared intact. Cell-autonomous function of Sp2 was identified
by deletion of Sp2 using mosaic analysis with double markers, which clearly established
that conditional Sp2-null NSCs and NPCs are M phase arrested in vivo. Importantly,
conditional deletion of Sp2 led to a decline in the generation of NPCs and neurons
in the developing and postnatal brains. Our findings implicate Sp2-dependent mechanisms
as novel regulators of cell cycle progression, the absence of which disrupts neurogenesis
in the embryonic and postnatal brain.
article_processing_charge: No
author:
- first_name: Huixuan
full_name: Liang, Huixuan
last_name: Liang
- first_name: Guanxi
full_name: Xiao, Guanxi
last_name: Xiao
- first_name: Haifeng
full_name: Yin, Haifeng
last_name: Yin
- first_name: Simon
full_name: Hippenmeyer, Simon
id: 37B36620-F248-11E8-B48F-1D18A9856A87
last_name: Hippenmeyer
orcid: 0000-0003-2279-1061
- first_name: Jonathan
full_name: Horowitz, Jonathan
last_name: Horowitz
- first_name: Troy
full_name: Ghashghaei, Troy
last_name: Ghashghaei
citation:
ama: Liang H, Xiao G, Yin H, Hippenmeyer S, Horowitz J, Ghashghaei T. Neural development
is dependent on the function of specificity protein 2 in cell cycle progression.
Development. 2013;140(3):552-561. doi:10.1242/dev.085621
apa: Liang, H., Xiao, G., Yin, H., Hippenmeyer, S., Horowitz, J., & Ghashghaei,
T. (2013). Neural development is dependent on the function of specificity protein
2 in cell cycle progression. Development. Company of Biologists. https://doi.org/10.1242/dev.085621
chicago: Liang, Huixuan, Guanxi Xiao, Haifeng Yin, Simon Hippenmeyer, Jonathan Horowitz,
and Troy Ghashghaei. “Neural Development Is Dependent on the Function of Specificity
Protein 2 in Cell Cycle Progression.” Development. Company of Biologists,
2013. https://doi.org/10.1242/dev.085621.
ieee: H. Liang, G. Xiao, H. Yin, S. Hippenmeyer, J. Horowitz, and T. Ghashghaei,
“Neural development is dependent on the function of specificity protein 2 in cell
cycle progression,” Development, vol. 140, no. 3. Company of Biologists,
pp. 552–561, 2013.
ista: Liang H, Xiao G, Yin H, Hippenmeyer S, Horowitz J, Ghashghaei T. 2013. Neural
development is dependent on the function of specificity protein 2 in cell cycle
progression. Development. 140(3), 552–561.
mla: Liang, Huixuan, et al. “Neural Development Is Dependent on the Function of
Specificity Protein 2 in Cell Cycle Progression.” Development, vol. 140,
no. 3, Company of Biologists, 2013, pp. 552–61, doi:10.1242/dev.085621.
short: H. Liang, G. Xiao, H. Yin, S. Hippenmeyer, J. Horowitz, T. Ghashghaei, Development
140 (2013) 552–561.
date_created: 2018-12-11T11:56:39Z
date_published: 2013-02-01T00:00:00Z
date_updated: 2021-01-12T06:56:23Z
day: '01'
department:
- _id: SiHi
doi: 10.1242/dev.085621
external_id:
pmid:
- '23293287'
intvolume: ' 140'
issue: '3'
language:
- iso: eng
main_file_link:
- open_access: '1'
url: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3561788/
month: '02'
oa: 1
oa_version: Submitted Version
page: 552 - 561
pmid: 1
publication: Development
publication_status: published
publisher: Company of Biologists
publist_id: '4681'
quality_controlled: '1'
scopus_import: 1
status: public
title: Neural development is dependent on the function of specificity protein 2 in
cell cycle progression
type: journal_article
user_id: 3E5EF7F0-F248-11E8-B48F-1D18A9856A87
volume: 140
year: '2013'
...
---
_id: '2269'
abstract:
- lang: eng
text: This paper presents a parallel, implementation-friendly analytic visibility
method for triangular meshes. Together with an analytic filter convolution, it
allows for a fully analytic solution to anti-aliased 3D mesh rendering on parallel
hardware. Building on recent works in computational geometry, we present a new
edge-triangle intersection algorithm and a novel method to complete the boundaries
of all visible triangle regions after a hidden line elimination step. All stages
of the method are embarrassingly parallel and easily implementable on parallel
hardware. A GPU implementation is discussed and performance characteristics of
the method are shown and compared to traditional sampling-based rendering methods.
acknowledgement: "Funding was provided by the FWF grant P20768-N13.\nWe want to thank
the reviewers for their insightful and helpful remarks and Gernot Ziegler for providing
help with CUDA. "
author:
- first_name: Thomas
full_name: Thomas Auzinger
id: 4718F954-F248-11E8-B48F-1D18A9856A87
last_name: Auzinger
orcid: 0000-0002-1546-3265
- first_name: Michael
full_name: Wimmer, Michael
last_name: Wimmer
- first_name: Stefan
full_name: Stefan Jeschke
id: 44D6411A-F248-11E8-B48F-1D18A9856A87
last_name: Jeschke
citation:
ama: 'Auzinger T, Wimmer M, Jeschke S. Analytic Visibility on the GPU. Computer
Graphics Forum. 2013;32(124):409-418. doi:DOI:
10.1111/cgf.12061'
apa: 'Auzinger, T., Wimmer, M., & Jeschke, S. (2013). Analytic Visibility on
the GPU. Computer Graphics Forum. Wiley-Blackwell. https://doi.org/DOI: 10.1111/cgf.12061'
chicago: 'Auzinger, Thomas, Michael Wimmer, and Stefan Jeschke. “Analytic Visibility
on the GPU.” Computer Graphics Forum. Wiley-Blackwell, 2013. https://doi.org/DOI: 10.1111/cgf.12061.'
ieee: T. Auzinger, M. Wimmer, and S. Jeschke, “Analytic Visibility on the GPU,”
Computer Graphics Forum, vol. 32, no. 124. Wiley-Blackwell, pp. 409–418,
2013.
ista: Auzinger T, Wimmer M, Jeschke S. 2013. Analytic Visibility on the GPU. Computer
Graphics Forum. 32(124), 409–418.
mla: 'Auzinger, Thomas, et al. “Analytic Visibility on the GPU.” Computer Graphics
Forum, vol. 32, no. 124, Wiley-Blackwell, 2013, pp. 409–18, doi:DOI: 10.1111/cgf.12061.'
short: T. Auzinger, M. Wimmer, S. Jeschke, Computer Graphics Forum 32 (2013) 409–418.
date_created: 2018-12-11T11:56:40Z
date_published: 2013-05-06T00:00:00Z
date_updated: 2021-01-12T06:56:25Z
day: '06'
doi: 'DOI: 10.1111/cgf.12061'
extern: 1
intvolume: ' 32'
issue: 124
month: '05'
page: 409 - 418
publication: Computer Graphics Forum
publication_status: published
publisher: Wiley-Blackwell
publist_id: '4675'
quality_controlled: 0
status: public
title: Analytic Visibility on the GPU
type: journal_article
volume: 32
year: '2013'
...
---
_id: '2270'
abstract:
- lang: eng
text: "Representation languages for coalitional games are a key research area in
algorithmic game theory. There is an inher-\r\nent tradeoff between how general
a language is, allowing it to capture more elaborate games, and how hard
\ it is computationally to optimize and solve such games. One prominent such
\ language is the simple yet expressive\r\nWeighted Graph Games (WGGs) representation
(Deng and Papadimitriou 1994), which maintains knowledge about synergies between
agents in the form of an edge weighted graph. We consider the problem of finding
\ the optimal coalition structure in WGGs. The agents in such games are vertices
in a graph, and the value of a coalition is the sum of the weights of the edges
present between coalition members. The optimal coalition structure is a partition
of the agents to coalitions, that maximizes the sum of utilities obtained by the
coalitions. We show that finding the optimal coalition structure is not
only hard for general graphs, but is also intractable for restricted families
such as planar graphs which are amenable for many other combinatorial problems.
\ We then provide algorithms with constant factor approximations for planar, minorfree
and bounded degree graphs."
author:
- first_name: Yoram
full_name: Bachrach, Yoram
last_name: Bachrach
- first_name: Pushmeet
full_name: Kohli, Pushmeet
last_name: Kohli
- first_name: Vladimir
full_name: Kolmogorov, Vladimir
id: 3D50B0BA-F248-11E8-B48F-1D18A9856A87
last_name: Kolmogorov
- first_name: Morteza
full_name: Zadimoghaddam, Morteza
last_name: Zadimoghaddam
citation:
ama: 'Bachrach Y, Kohli P, Kolmogorov V, Zadimoghaddam M. Optimal Coalition Structures
in Cooperative Graph Games. In: AAAI Press; 2013:81-87.'
apa: 'Bachrach, Y., Kohli, P., Kolmogorov, V., & Zadimoghaddam, M. (2013). Optimal
Coalition Structures in Cooperative Graph Games (pp. 81–87). Presented at the
AAAI: Conference on Artificial Intelligence, Bellevue, WA, United States: AAAI
Press.'
chicago: Bachrach, Yoram, Pushmeet Kohli, Vladimir Kolmogorov, and Morteza Zadimoghaddam.
“Optimal Coalition Structures in Cooperative Graph Games,” 81–87. AAAI Press,
2013.
ieee: 'Y. Bachrach, P. Kohli, V. Kolmogorov, and M. Zadimoghaddam, “Optimal Coalition
Structures in Cooperative Graph Games,” presented at the AAAI: Conference on Artificial
Intelligence, Bellevue, WA, United States, 2013, pp. 81–87.'
ista: 'Bachrach Y, Kohli P, Kolmogorov V, Zadimoghaddam M. 2013. Optimal Coalition
Structures in Cooperative Graph Games. AAAI: Conference on Artificial Intelligence,
81–87.'
mla: Bachrach, Yoram, et al. Optimal Coalition Structures in Cooperative Graph
Games. AAAI Press, 2013, pp. 81–87.
short: Y. Bachrach, P. Kohli, V. Kolmogorov, M. Zadimoghaddam, in:, AAAI Press,
2013, pp. 81–87.
conference:
end_date: 2013-07-18
location: Bellevue, WA, United States
name: 'AAAI: Conference on Artificial Intelligence'
start_date: 2013-07-14
date_created: 2018-12-11T11:56:41Z
date_published: 2013-12-31T00:00:00Z
date_updated: 2021-01-12T06:56:25Z
day: '31'
department:
- _id: VlKo
external_id:
arxiv:
- '1108.5248'
language:
- iso: eng
main_file_link:
- open_access: '1'
url: http://arxiv.org/abs/1108.5248
month: '12'
oa: 1
oa_version: None
page: 81-87
publication_status: published
publisher: AAAI Press
publist_id: '4674'
quality_controlled: '1'
status: public
title: Optimal Coalition Structures in Cooperative Graph Games
type: conference
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
year: '2013'
...
---
_id: '2273'
abstract:
- lang: eng
text: We propose a new family of message passing techniques for MAP estimation in
graphical models which we call Sequential Reweighted Message Passing (SRMP). Special
cases include well-known techniques such as Min-Sum Diusion (MSD) and a faster
Sequential Tree-Reweighted Message Passing (TRW-S). Importantly, our derivation
is simpler than the original derivation of TRW-S, and does not involve a decomposition
into trees. This allows easy generalizations. We present such a generalization
for the case of higher-order graphical models, and test it on several real-world
problems with promising results.
author:
- first_name: Vladimir
full_name: Vladimir Kolmogorov
id: 3D50B0BA-F248-11E8-B48F-1D18A9856A87
last_name: Kolmogorov
citation:
ama: Kolmogorov V. Reweighted Message Passing Revisited. IST Austria; 2013.
apa: Kolmogorov, V. (2013). Reweighted message passing revisited. IST Austria.
chicago: Kolmogorov, Vladimir. Reweighted Message Passing Revisited. IST
Austria, 2013.
ieee: V. Kolmogorov, Reweighted message passing revisited. IST Austria, 2013.
ista: Kolmogorov V. 2013. Reweighted message passing revisited, IST Austria,p.
mla: Kolmogorov, Vladimir. Reweighted Message Passing Revisited. IST Austria,
2013.
short: V. Kolmogorov, Reweighted Message Passing Revisited, IST Austria, 2013.
date_created: 2018-12-11T11:56:42Z
date_published: 2013-09-22T00:00:00Z
date_updated: 2019-01-24T13:07:32Z
day: '22'
department:
- _id: VlKo
extern: 0
main_file_link:
- open_access: '1'
url: http://arxiv.org/abs/1309.5655
month: '09'
oa: 1
publication_status: published
publisher: IST Austria
publist_id: '4671'
quality_controlled: 0
status: public
title: Reweighted message passing revisited
type: report
year: '2013'
...
---
_id: '2278'
abstract:
- lang: eng
text: It is firmly established that interactions between neurons and glia are fundamental
across species for the correct establishment of a functional brain. Here, we found
that the glia of the Drosophila larval brain display an essential non-autonomous
role during the development of the optic lobe. The optic lobe develops from neuroepithelial
cells that proliferate by dividing symmetrically until they switch to asymmetric/differentiative
divisions that generate neuroblasts. The proneural gene lethal of scute (l9sc)
is transiently activated by the epidermal growth factor receptor (EGFR)-Ras signal
transduction pathway at the leading edge of a proneural wave that sweeps from
medial to lateral neuroepithelium, promoting this switch. This process is tightly
regulated by the tissue-autonomous function within the neuroepithelium of multiple
signaling pathways, including EGFR-Ras and Notch. This study shows that the Notch
ligand Serrate (Ser) is expressed in the glia and it forms a complex in vivo with
Notch and Canoe, which colocalize at the adherens junctions of neuroepithelial
cells. This complex is crucial for interactions between glia and neuroepithelial
cells during optic lobe development. Ser is tissue-autonomously required in the
glia where it activates Notch to regulate its proliferation, and non-autonomously
in the neuroepithelium where Ser induces Notch signaling to avoid the premature
activation of the EGFR-Ras pathway and hence of L9sc. Interestingly, different
Notch activity reporters showed very different expression patterns in the glia
and in the neuroepithelium, suggesting the existence of tissue-specific factors
that promote the expression of particular Notch target genes or/and a reporter
response dependent on different thresholds of Notch signaling.
author:
- first_name: Raquel
full_name: Pérez Gómez, Raquel
last_name: Pérez Gómez
- first_name: Jana
full_name: Slovakova, Jana
id: 30F3F2F0-F248-11E8-B48F-1D18A9856A87
last_name: Slovakova
- first_name: Noemí
full_name: Rives Quinto, Noemí
last_name: Rives Quinto
- first_name: Alena
full_name: Krejčí, Alena
last_name: Krejčí
- first_name: Ana
full_name: Carmena, Ana
last_name: Carmena
citation:
ama: Pérez Gómez R, Slovakova J, Rives Quinto N, Krejčí A, Carmena A. A serrate-notch-canoe
complex mediates essential interactions between glia and neuroepithelial cells
during Drosophila optic lobe development. Journal of Cell Science. 2013;126(21):4873-4884.
doi:10.1242/jcs.125617
apa: Pérez Gómez, R., Slovakova, J., Rives Quinto, N., Krejčí, A., & Carmena,
A. (2013). A serrate-notch-canoe complex mediates essential interactions between
glia and neuroepithelial cells during Drosophila optic lobe development. Journal
of Cell Science. Company of Biologists. https://doi.org/10.1242/jcs.125617
chicago: Pérez Gómez, Raquel, Jana Slovakova, Noemí Rives Quinto, Alena Krejčí,
and Ana Carmena. “A Serrate-Notch-Canoe Complex Mediates Essential Interactions
between Glia and Neuroepithelial Cells during Drosophila Optic Lobe Development.”
Journal of Cell Science. Company of Biologists, 2013. https://doi.org/10.1242/jcs.125617.
ieee: R. Pérez Gómez, J. Slovakova, N. Rives Quinto, A. Krejčí, and A. Carmena,
“A serrate-notch-canoe complex mediates essential interactions between glia and
neuroepithelial cells during Drosophila optic lobe development,” Journal of
Cell Science, vol. 126, no. 21. Company of Biologists, pp. 4873–4884, 2013.
ista: Pérez Gómez R, Slovakova J, Rives Quinto N, Krejčí A, Carmena A. 2013. A serrate-notch-canoe
complex mediates essential interactions between glia and neuroepithelial cells
during Drosophila optic lobe development. Journal of Cell Science. 126(21), 4873–4884.
mla: Pérez Gómez, Raquel, et al. “A Serrate-Notch-Canoe Complex Mediates Essential
Interactions between Glia and Neuroepithelial Cells during Drosophila Optic Lobe
Development.” Journal of Cell Science, vol. 126, no. 21, Company of Biologists,
2013, pp. 4873–84, doi:10.1242/jcs.125617.
short: R. Pérez Gómez, J. Slovakova, N. Rives Quinto, A. Krejčí, A. Carmena, Journal
of Cell Science 126 (2013) 4873–4884.
date_created: 2018-12-11T11:56:43Z
date_published: 2013-11-01T00:00:00Z
date_updated: 2021-01-12T06:56:29Z
day: '01'
department:
- _id: CaHe
doi: 10.1242/jcs.125617
intvolume: ' 126'
issue: '21'
language:
- iso: eng
month: '11'
oa_version: None
page: 4873 - 4884
publication: Journal of Cell Science
publication_status: published
publisher: Company of Biologists
publist_id: '4658'
quality_controlled: '1'
scopus_import: 1
status: public
title: A serrate-notch-canoe complex mediates essential interactions between glia
and neuroepithelial cells during Drosophila optic lobe development
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 126
year: '2013'
...
---
_id: '2276'
abstract:
- lang: eng
text: The problem of minimizing the Potts energy function frequently occurs in computer
vision applications. One way to tackle this NP-hard problem was proposed by Kovtun
[19, 20]. It identifies a part of an optimal solution by running k maxflow computations,
where k is the number of labels. The number of “labeled” pixels can be significant
in some applications, e.g. 50-93% in our tests for stereo. We show how to reduce
the runtime to O (log k) maxflow computations (or one parametric maxflow computation).
Furthermore, the output of our algorithm allows to speed-up the subsequent alpha
expansion for the unlabeled part, or can be used as it is for time-critical applications.
To derive our technique, we generalize the algorithm of Felzenszwalb et al. [7]
for Tree Metrics . We also show a connection to k-submodular functions from combinatorial
optimization, and discuss k-submodular relaxations for general energy functions.
author:
- first_name: Igor
full_name: Gridchyn, Igor
id: 4B60654C-F248-11E8-B48F-1D18A9856A87
last_name: Gridchyn
- first_name: Vladimir
full_name: Kolmogorov, Vladimir
id: 3D50B0BA-F248-11E8-B48F-1D18A9856A87
last_name: Kolmogorov
citation:
ama: 'Gridchyn I, Kolmogorov V. Potts model, parametric maxflow and k-submodular
functions. In: IEEE; 2013:2320-2327. doi:10.1109/ICCV.2013.288'
apa: 'Gridchyn, I., & Kolmogorov, V. (2013). Potts model, parametric maxflow
and k-submodular functions (pp. 2320–2327). Presented at the ICCV: International
Conference on Computer Vision, Sydney, Australia: IEEE. https://doi.org/10.1109/ICCV.2013.288'
chicago: Gridchyn, Igor, and Vladimir Kolmogorov. “Potts Model, Parametric Maxflow
and k-Submodular Functions,” 2320–27. IEEE, 2013. https://doi.org/10.1109/ICCV.2013.288.
ieee: 'I. Gridchyn and V. Kolmogorov, “Potts model, parametric maxflow and k-submodular
functions,” presented at the ICCV: International Conference on Computer Vision,
Sydney, Australia, 2013, pp. 2320–2327.'
ista: 'Gridchyn I, Kolmogorov V. 2013. Potts model, parametric maxflow and k-submodular
functions. ICCV: International Conference on Computer Vision, 2320–2327.'
mla: Gridchyn, Igor, and Vladimir Kolmogorov. Potts Model, Parametric Maxflow
and k-Submodular Functions. IEEE, 2013, pp. 2320–27, doi:10.1109/ICCV.2013.288.
short: I. Gridchyn, V. Kolmogorov, in:, IEEE, 2013, pp. 2320–2327.
conference:
end_date: 2013-12-08
location: Sydney, Australia
name: 'ICCV: International Conference on Computer Vision'
start_date: 2013-12-01
date_created: 2018-12-11T11:56:43Z
date_published: 2013-12-01T00:00:00Z
date_updated: 2021-01-12T06:56:28Z
day: '01'
department:
- _id: JoCs
- _id: VlKo
doi: 10.1109/ICCV.2013.288
external_id:
arxiv:
- '1310.1771'
language:
- iso: eng
main_file_link:
- open_access: '1'
url: http://arxiv.org/abs/1310.1771
month: '12'
oa: 1
oa_version: Preprint
page: 2320 - 2327
publication_status: published
publisher: IEEE
publist_id: '4668'
quality_controlled: '1'
status: public
title: Potts model, parametric maxflow and k-submodular functions
type: conference
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
year: '2013'
...
---
_id: '2280'
abstract:
- lang: eng
text: The problem of packing ellipsoids of different sizes and shapes into an ellipsoidal
container so as to minimize a measure of overlap between ellipsoids is considered.
A bilevel optimization formulation is given, together with an algorithm for the
general case and a simpler algorithm for the special case in which all ellipsoids
are in fact spheres. Convergence results are proved and computational experience
is described and illustrated. The motivating application-chromosome organization
in the human cell nucleus-is discussed briefly, and some illustrative results
are presented.
author:
- first_name: Caroline
full_name: Uhler, Caroline
id: 49ADD78E-F248-11E8-B48F-1D18A9856A87
last_name: Uhler
orcid: 0000-0002-7008-0216
- first_name: Stephen
full_name: Wright, Stephen
last_name: Wright
citation:
ama: Uhler C, Wright S. Packing ellipsoids with overlap. SIAM Review. 2013;55(4):671-706.
doi:10.1137/120872309
apa: Uhler, C., & Wright, S. (2013). Packing ellipsoids with overlap. SIAM
Review. Society for Industrial and Applied Mathematics . https://doi.org/10.1137/120872309
chicago: Uhler, Caroline, and Stephen Wright. “Packing Ellipsoids with Overlap.”
SIAM Review. Society for Industrial and Applied Mathematics , 2013. https://doi.org/10.1137/120872309.
ieee: C. Uhler and S. Wright, “Packing ellipsoids with overlap,” SIAM Review,
vol. 55, no. 4. Society for Industrial and Applied Mathematics , pp. 671–706,
2013.
ista: Uhler C, Wright S. 2013. Packing ellipsoids with overlap. SIAM Review. 55(4),
671–706.
mla: Uhler, Caroline, and Stephen Wright. “Packing Ellipsoids with Overlap.” SIAM
Review, vol. 55, no. 4, Society for Industrial and Applied Mathematics , 2013,
pp. 671–706, doi:10.1137/120872309.
short: C. Uhler, S. Wright, SIAM Review 55 (2013) 671–706.
date_created: 2018-12-11T11:56:44Z
date_published: 2013-11-07T00:00:00Z
date_updated: 2021-01-12T06:56:30Z
day: '07'
department:
- _id: CaUh
doi: 10.1137/120872309
external_id:
arxiv:
- '1204.0235'
intvolume: ' 55'
issue: '4'
language:
- iso: eng
main_file_link:
- open_access: '1'
url: http://arxiv.org/abs/1204.0235
month: '11'
oa: 1
oa_version: Preprint
page: 671 - 706
publication: SIAM Review
publication_status: published
publisher: 'Society for Industrial and Applied Mathematics '
publist_id: '4655'
quality_controlled: '1'
scopus_import: 1
status: public
title: Packing ellipsoids with overlap
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 55
year: '2013'
...
---
_id: '2287'
abstract:
- lang: eng
text: Negative frequency-dependent selection should result in equal sex ratios in
large populations of dioecious flowering plants, but deviations from equality
are commonly reported. A variety of ecological and genetic factors can explain
biased sex ratios, although the mechanisms involved are not well understood. Most
dioecious species are long-lived and/or clonal complicating efforts to identify
stages during the life cycle when biases develop. We investigated the demographic
correlates of sex-ratio variation in two chromosome races of Rumex hastatulus,
an annual, wind-pollinated colonizer of open habitats from the southern USA. We
examined sex ratios in 46 populations and evaluated the hypothesis that the proximity
of males in the local mating environment, through its influence on gametophytic
selection, is the primary cause of female-biased sex ratios. Female-biased sex
ratios characterized most populations of R. hastatulus (mean sex ratio = 0.62),
with significant female bias in 89% of populations. Large, high-density populations
had the highest proportion of females, whereas smaller, low-density populations
had sex ratios closer to equality. Progeny sex ratios were more female biased
when males were in closer proximity to females, a result consistent with the gametophytic
selection hypothesis. Our results suggest that interactions between demographic
and genetic factors are probably the main cause of female-biased sex ratios in
R. hastatulus. The annual life cycle of this species may limit the scope for selection
against males and may account for the weaker degree of bias in comparison with
perennial Rumex species.
author:
- first_name: Melinda
full_name: Pickup, Melinda
id: 2C78037E-F248-11E8-B48F-1D18A9856A87
last_name: Pickup
orcid: 0000-0001-6118-0541
- first_name: Spencer
full_name: Barrett, Spencer
last_name: Barrett
citation:
ama: Pickup M, Barrett S. The influence of demography and local mating environment
on sex ratios in a wind-pollinated dioecious plant. Ecology and Evolution.
2013;3(3):629-639. doi:10.1002/ece3.465
apa: Pickup, M., & Barrett, S. (2013). The influence of demography and local
mating environment on sex ratios in a wind-pollinated dioecious plant. Ecology
and Evolution. Wiley-Blackwell. https://doi.org/10.1002/ece3.465
chicago: Pickup, Melinda, and Spencer Barrett. “The Influence of Demography and
Local Mating Environment on Sex Ratios in a Wind-Pollinated Dioecious Plant.”
Ecology and Evolution. Wiley-Blackwell, 2013. https://doi.org/10.1002/ece3.465.
ieee: M. Pickup and S. Barrett, “The influence of demography and local mating environment
on sex ratios in a wind-pollinated dioecious plant,” Ecology and Evolution,
vol. 3, no. 3. Wiley-Blackwell, pp. 629–639, 2013.
ista: Pickup M, Barrett S. 2013. The influence of demography and local mating environment
on sex ratios in a wind-pollinated dioecious plant. Ecology and Evolution. 3(3),
629–639.
mla: Pickup, Melinda, and Spencer Barrett. “The Influence of Demography and Local
Mating Environment on Sex Ratios in a Wind-Pollinated Dioecious Plant.” Ecology
and Evolution, vol. 3, no. 3, Wiley-Blackwell, 2013, pp. 629–39, doi:10.1002/ece3.465.
short: M. Pickup, S. Barrett, Ecology and Evolution 3 (2013) 629–639.
date_created: 2018-12-11T11:56:47Z
date_published: 2013-03-01T00:00:00Z
date_updated: 2021-01-12T06:56:32Z
day: '01'
ddc:
- '576'
department:
- _id: NiBa
doi: 10.1002/ece3.465
file:
- access_level: open_access
checksum: b5531bab4c0dec396bf5c8497fe178bf
content_type: application/pdf
creator: system
date_created: 2018-12-12T10:17:35Z
date_updated: 2020-07-14T12:45:37Z
file_id: '5290'
file_name: IST-2016-416-v1+1_Pickup_et_al-2013-Ecology_and_Evolution.pdf
file_size: 626949
relation: main_file
file_date_updated: 2020-07-14T12:45:37Z
has_accepted_license: '1'
intvolume: ' 3'
issue: '3'
language:
- iso: eng
month: '03'
oa: 1
oa_version: Published Version
page: 629 - 639
publication: Ecology and Evolution
publication_status: published
publisher: Wiley-Blackwell
publist_id: '4644'
pubrep_id: '416'
quality_controlled: '1'
scopus_import: 1
status: public
title: The influence of demography and local mating environment on sex ratios in a
wind-pollinated dioecious plant
tmp:
image: /images/cc_by.png
legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
short: CC BY (4.0)
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 3
year: '2013'
...
---
_id: '2282'
abstract:
- lang: eng
text: Epithelial spreading is a common and fundamental aspect of various developmental
and disease-related processes such as epithelial closure and wound healing. A
key challenge for epithelial tissues undergoing spreading is to increase their
surface area without disrupting epithelial integrity. Here we show that orienting
cell divisions by tension constitutes an efficient mechanism by which the enveloping
cell layer (EVL) releases anisotropic tension while undergoing spreading during
zebrafish epiboly. The control of EVL cell-division orientation by tension involves
cell elongation and requires myosin II activity to align the mitotic spindle with
the main tension axis. We also found that in the absence of tension-oriented cell
divisions and in the presence of increased tissue tension, EVL cells undergo ectopic
fusions, suggesting that the reduction of tension anisotropy by oriented cell
divisions is required to prevent EVL cells from fusing. We conclude that cell-division
orientation by tension constitutes a key mechanism for limiting tension anisotropy
and thus promoting tissue spreading during EVL epiboly.
acknowledged_ssus:
- _id: PreCl
- _id: Bio
acknowledgement: 'This work was supported by the IST Austria and MPI-CBG '
author:
- first_name: Pedro
full_name: Campinho, Pedro
id: 3AFBBC42-F248-11E8-B48F-1D18A9856A87
last_name: Campinho
orcid: 0000-0002-8526-5416
- first_name: Martin
full_name: Behrndt, Martin
id: 3ECECA3A-F248-11E8-B48F-1D18A9856A87
last_name: Behrndt
- first_name: Jonas
full_name: Ranft, Jonas
last_name: Ranft
- first_name: Thomas
full_name: Risler, Thomas
last_name: Risler
- first_name: Nicolas
full_name: Minc, Nicolas
last_name: Minc
- first_name: Carl-Philipp J
full_name: Heisenberg, Carl-Philipp J
id: 39427864-F248-11E8-B48F-1D18A9856A87
last_name: Heisenberg
orcid: 0000-0002-0912-4566
citation:
ama: Campinho P, Behrndt M, Ranft J, Risler T, Minc N, Heisenberg C-PJ. Tension-oriented
cell divisions limit anisotropic tissue tension in epithelial spreading during
zebrafish epiboly. Nature Cell Biology. 2013;15:1405-1414. doi:10.1038/ncb2869
apa: Campinho, P., Behrndt, M., Ranft, J., Risler, T., Minc, N., & Heisenberg,
C.-P. J. (2013). Tension-oriented cell divisions limit anisotropic tissue tension
in epithelial spreading during zebrafish epiboly. Nature Cell Biology.
Nature Publishing Group. https://doi.org/10.1038/ncb2869
chicago: Campinho, Pedro, Martin Behrndt, Jonas Ranft, Thomas Risler, Nicolas Minc,
and Carl-Philipp J Heisenberg. “Tension-Oriented Cell Divisions Limit Anisotropic
Tissue Tension in Epithelial Spreading during Zebrafish Epiboly.” Nature Cell
Biology. Nature Publishing Group, 2013. https://doi.org/10.1038/ncb2869.
ieee: P. Campinho, M. Behrndt, J. Ranft, T. Risler, N. Minc, and C.-P. J. Heisenberg,
“Tension-oriented cell divisions limit anisotropic tissue tension in epithelial
spreading during zebrafish epiboly,” Nature Cell Biology, vol. 15. Nature
Publishing Group, pp. 1405–1414, 2013.
ista: Campinho P, Behrndt M, Ranft J, Risler T, Minc N, Heisenberg C-PJ. 2013. Tension-oriented
cell divisions limit anisotropic tissue tension in epithelial spreading during
zebrafish epiboly. Nature Cell Biology. 15, 1405–1414.
mla: Campinho, Pedro, et al. “Tension-Oriented Cell Divisions Limit Anisotropic
Tissue Tension in Epithelial Spreading during Zebrafish Epiboly.” Nature Cell
Biology, vol. 15, Nature Publishing Group, 2013, pp. 1405–14, doi:10.1038/ncb2869.
short: P. Campinho, M. Behrndt, J. Ranft, T. Risler, N. Minc, C.-P.J. Heisenberg,
Nature Cell Biology 15 (2013) 1405–1414.
date_created: 2018-12-11T11:56:45Z
date_published: 2013-11-10T00:00:00Z
date_updated: 2023-02-21T17:02:44Z
day: '10'
department:
- _id: CaHe
doi: 10.1038/ncb2869
intvolume: ' 15'
language:
- iso: eng
main_file_link:
- open_access: '1'
url: http://hal.upmc.fr/hal-00983313/
month: '11'
oa: 1
oa_version: Submitted Version
page: 1405 - 1414
project:
- _id: 252ABD0A-B435-11E9-9278-68D0E5697425
call_identifier: FWF
grant_number: I 930-B20
name: Control of Epithelial Cell Layer Spreading in Zebrafish
publication: Nature Cell Biology
publication_status: published
publisher: Nature Publishing Group
publist_id: '4652'
quality_controlled: '1'
related_material:
record:
- id: '1403'
relation: dissertation_contains
status: public
scopus_import: 1
status: public
title: Tension-oriented cell divisions limit anisotropic tissue tension in epithelial
spreading during zebrafish epiboly
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 15
year: '2013'
...
---
_id: '2283'
abstract:
- lang: eng
text: Pathogens exert a strong selection pressure on organisms to evolve effective
immune defences. In addition to individual immunity, social organisms can act
cooperatively to produce collective defences. In many ant species, queens have
the option to found a colony alone or in groups with other, often unrelated, conspecifics.
These associations are transient, usually lasting only as long as each queen benefits
from the presence of others. In fact, once the first workers emerge, queens fight
to the death for dominance. One potential advantage of co-founding may be that
queens benefit from collective disease defences, such as mutual grooming, that
act against common soil pathogens. We test this hypothesis by exposing single
and co-founding queens to a fungal parasite, in order to assess whether queens
in co-founding associations have improved survival. Surprisingly, co-foundresses
exposed to the entomopathogenic fungus Metarhizium did not engage in cooperative
disease defences, and consequently, we find no direct benefit of multiple queens
on survival. However, an indirect benefit was observed, with parasite-exposed
queens producing more brood when they co-founded, than when they were alone. We
suggest this is due to a trade-off between reproduction and immunity. Additionally,
we report an extraordinary ability of the queens to tolerate an infection for
long periods after parasite exposure. Our study suggests that there are no social
immunity benefits for co-founding ant queens, but that in parasite-rich environments,
the presence of additional queens may nevertheless improve the chances of colony
founding success.
author:
- first_name: Christopher
full_name: Pull, Christopher
id: 3C7F4840-F248-11E8-B48F-1D18A9856A87
last_name: Pull
orcid: 0000-0003-1122-3982
- first_name: William
full_name: Hughes, William
last_name: Hughes
- first_name: Markus
full_name: Brown, Markus
id: 3DAB9AFC-F248-11E8-B48F-1D18A9856A87
last_name: Brown
citation:
ama: 'Pull C, Hughes W, Brown M. Tolerating an infection: an indirect benefit of
co-founding queen associations in the ant Lasius niger . Naturwissenschaften.
2013;100(12):1125-1136. doi:10.1007/s00114-013-1115-5'
apa: 'Pull, C., Hughes, W., & Brown, M. (2013). Tolerating an infection: an
indirect benefit of co-founding queen associations in the ant Lasius niger . Naturwissenschaften.
Springer. https://doi.org/10.1007/s00114-013-1115-5'
chicago: 'Pull, Christopher, William Hughes, and Markus Brown. “Tolerating an Infection:
An Indirect Benefit of Co-Founding Queen Associations in the Ant Lasius Niger
.” Naturwissenschaften. Springer, 2013. https://doi.org/10.1007/s00114-013-1115-5.'
ieee: 'C. Pull, W. Hughes, and M. Brown, “Tolerating an infection: an indirect benefit
of co-founding queen associations in the ant Lasius niger ,” Naturwissenschaften,
vol. 100, no. 12. Springer, pp. 1125–1136, 2013.'
ista: 'Pull C, Hughes W, Brown M. 2013. Tolerating an infection: an indirect benefit
of co-founding queen associations in the ant Lasius niger . Naturwissenschaften.
100(12), 1125–1136.'
mla: 'Pull, Christopher, et al. “Tolerating an Infection: An Indirect Benefit of
Co-Founding Queen Associations in the Ant Lasius Niger .” Naturwissenschaften,
vol. 100, no. 12, Springer, 2013, pp. 1125–36, doi:10.1007/s00114-013-1115-5.'
short: C. Pull, W. Hughes, M. Brown, Naturwissenschaften 100 (2013) 1125–1136.
date_created: 2018-12-11T11:56:45Z
date_published: 2013-11-14T00:00:00Z
date_updated: 2021-01-12T06:56:31Z
day: '14'
department:
- _id: SyCr
doi: 10.1007/s00114-013-1115-5
intvolume: ' 100'
issue: '12'
language:
- iso: eng
month: '11'
oa_version: None
page: 1125 - 1136
publication: Naturwissenschaften
publication_status: published
publisher: Springer
publist_id: '4649'
quality_controlled: '1'
scopus_import: 1
status: public
title: 'Tolerating an infection: an indirect benefit of co-founding queen associations
in the ant Lasius niger '
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 100
year: '2013'
...