TY - CONF AB - Fluxoid quantization provides a direct means to study phase coherence. In cuprate superconductors, there have been observations which suggest that phase coherent superconducting fluctuations may persist at temperatures significantly above Tc. The focus of this work is to study the vortex states in mesoscopic cuprate superconducting samples to directly probe phase coherence over a wide range of temperatures. We present cantilever torque susceptometry measurements of micron and sub-micron size Bi2212 rings and disks. The high sensitivity of this technique allowed observation of transitions between different fluxoid states of a single ring, and the discrete vortex states of micron size disks. The dependence of magnetic susceptibility on diameter and wall thickness of the ring was investigated. Measurements were made at different values of the in-plane magnetic field, and over a wide range of temperatures. AU - Polshyn, Hryhoriy AU - Budakian, Raffi AU - Gu, Genda ID - 10749 IS - 1 SN - 0003-0503 T2 - APS March Meeting 2013 TI - Cantilever micro-susceptometry of mesoscopic Bi2212 samples VL - 58 ER - TY - JOUR AB - Due to their sessile lifestyles, plants need to deal with the limitations and stresses imposed by the changing environment. Plants cope with these by a remarkable developmental flexibility, which is embedded in their strategy to survive. Plants can adjust their size, shape and number of organs, bend according to gravity and light, and regenerate tissues that were damaged, utilizing a coordinating, intercellular signal, the plant hormone, auxin. Another versatile signal is the cation, Ca2+, which is a crucial second messenger for many rapid cellular processes during responses to a wide range of endogenous and environmental signals, such as hormones, light, drought stress and others. Auxin is a good candidate for one of these Ca2+-activating signals. However, the role of auxin-induced Ca2+ signaling is poorly understood. Here, we will provide an overview of possible developmental and physiological roles, as well as mechanisms underlying the interconnection of Ca2+ and auxin signaling. AU - Vanneste, Steffen AU - Friml, Jiří ID - 10895 IS - 4 JF - Plants KW - Plant Science KW - Ecology KW - Ecology KW - Evolution KW - Behavior and Systematics SN - 2223-7747 TI - Calcium: The missing link in auxin action VL - 2 ER - TY - CONF AB - A prominent remedy to multicore scalability issues in concurrent data structure implementations is to relax the sequential specification of the data structure. We present distributed queues (DQ), a new family of relaxed concurrent queue implementations. DQs implement relaxed queues with linearizable emptiness check and either configurable or bounded out-of-order behavior or pool behavior. Our experiments show that DQs outperform and outscale in micro- and macrobenchmarks all strict and relaxed queue as well as pool implementations that we considered. AU - Haas, Andreas AU - Lippautz, Michael AU - Henzinger, Thomas A AU - Payer, Hannes AU - Sokolova, Ana AU - Kirsch, Christoph M. AU - Sezgin, Ali ID - 10898 IS - 5 SN - 978-145032053-5 T2 - Proceedings of the ACM International Conference on Computing Frontiers - CF '13 TI - Distributed queues in shared memory: Multicore performance and scalability through quantitative relaxation ER - TY - CHAP AU - Barton, Nicholas H ID - 10899 KW - Adaptive landscape KW - Cline KW - Coalescent process KW - Gene flow KW - Hybrid zone KW - Local adaptation KW - Natural selection KW - Neutral theory KW - Population structure KW - Speciation SN - 978-0-12-384720-1 T2 - Encyclopedia of Biodiversity TI - Differentiation ER - TY - JOUR AB - Faithful execution of developmental gene expression programs occurs at multiple levels and involves many different components such as transcription factors, histone-modification enzymes, and mRNA processing proteins. Recent evidence suggests that nucleoporins, well known components that control nucleo-cytoplasmic trafficking, have wide-ranging functions in developmental gene regulation that potentially extend beyond their role in nuclear transport. Whether the unexpected role of nuclear pore proteins in transcription regulation, which initially has been described in fungi and flies, also applies to human cells is unknown. Here we show at a genome-wide level that the nuclear pore protein NUP98 associates with developmentally regulated genes active during human embryonic stem cell differentiation. Overexpression of a dominant negative fragment of NUP98 levels decreases expression levels of NUP98-bound genes. In addition, we identify two modes of developmental gene regulation by NUP98 that are differentiated by the spatial localization of NUP98 target genes. Genes in the initial stage of developmental induction can associate with NUP98 that is embedded in the nuclear pores at the nuclear periphery. Alternatively, genes that are highly induced can interact with NUP98 in the nuclear interior, away from the nuclear pores. This work demonstrates for the first time that NUP98 dynamically associates with the human genome during differentiation, revealing a role of a nuclear pore protein in regulating developmental gene expression programs. AU - Liang, Yun AU - Franks, Tobias M. AU - Marchetto, Maria C. AU - Gage, Fred H. AU - HETZER, Martin W ID - 11086 IS - 2 JF - PLoS Genetics KW - Cancer Research KW - Genetics (clinical) KW - Genetics KW - Molecular Biology KW - Ecology KW - Evolution KW - Behavior and Systematics SN - 1553-7404 TI - Dynamic association of NUP98 with the human genome VL - 9 ER -