TY - JOUR
AB - Hill's Conjecture states that the crossing number cr(đŸđ) of the complete graph đŸđ in the plane (equivalently, the sphere) is 14âđ2ââđâ12ââđâ22ââđâ32â=đ4/64+đ(đ3) . Moon proved that the expected number of crossings in a spherical drawing in which the points are randomly distributed and joined by geodesics is precisely đ4/64+đ(đ3) , thus matching asymptotically the conjectured value of cr(đŸđ) . Let crđ(đș) denote the crossing number of a graph đș in the projective plane. Recently, Elkies proved that the expected number of crossings in a naturally defined random projective plane drawing of đŸđ is (đ4/8đ2)+đ(đ3) . In analogy with the relation of Moon's result to Hill's conjecture, Elkies asked if limđâââcrđ(đŸđ)/đ4=1/8đ2 . We construct drawings of đŸđ in the projective plane that disprove this.
AU - Arroyo Guevara, Alan M
AU - Mcquillan, Dan
AU - Richter, R. Bruce
AU - Salazar, Gelasio
AU - Sullivan, Matthew
ID - 9295
JF - Journal of Graph Theory
SN - 0364-9024
TI - Drawings of complete graphs in the projective plane
ER -
TY - JOUR
AB - We consider planning problems for graphs, Markov Decision Processes (MDPs), and games on graphs in an explicit state space. While graphs represent the most basic planning model, MDPs represent interaction with nature and games on graphs represent interaction with an adversarial environment. We consider two planning problems with k different target sets: (a) the coverage problem asks whether there is a plan for each individual target set; and (b) the sequential target reachability problem asks whether the targets can be reached in a given sequence. For the coverage problem, we present a linear-time algorithm for graphs, and quadratic conditional lower bound for MDPs and games on graphs. For the sequential target problem, we present a linear-time algorithm for graphs, a sub-quadratic algorithm for MDPs, and a quadratic conditional lower bound for games on graphs. Our results with conditional lower bounds, based on the boolean matrix multiplication (BMM) conjecture and strong exponential time hypothesis (SETH), establish (i) model-separation results showing that for the coverage problem MDPs and games on graphs are harder than graphs, and for the sequential reachability problem games on graphs are harder than MDPs and graphs; and (ii) problem-separation results showing that for MDPs the coverage problem is harder than the sequential target problem.
AU - Chatterjee, Krishnendu
AU - DvoĆĂĄk, Wolfgang
AU - Henzinger, Monika
AU - Svozil, Alexander
ID - 9293
IS - 8
JF - Artificial Intelligence
SN - 00043702
TI - Algorithms and conditional lower bounds for planning problems
VL - 297
ER -
TY - JOUR
AB - In this issue of Developmental Cell, Doyle and colleagues identify periodic anterior contraction as a characteristic feature of fibroblasts and mesenchymal cancer cells embedded in 3D collagen gels. This contractile mechanism generates a matrix prestrain required for crawling in fibrous 3D environments.
AU - GĂ€rtner, Florian R
AU - Sixt, Michael K
ID - 9294
IS - 6
JF - Developmental Cell
SN - 15345807
TI - Engaging the front wheels to drive through fibrous terrain
VL - 56
ER -
TY - JOUR
AB - We establish finite time extinction with probability one for weak solutions of the CauchyâDirichlet problem for the 1D stochastic porous medium equation with Stratonovich transport noise and compactly supported smooth initial datum. Heuristically, this is expected to hold because Brownian motion has average spread rate O(t12) whereas the support of solutions to the deterministic PME grows only with rate O(t1m+1). The rigorous proof relies on a contraction principle up to time-dependent shift for WongâZakai type approximations, the transformation to a deterministic PME with two copies of a Brownian path as the lateral boundary, and techniques from the theory of viscosity solutions.
AU - Hensel, Sebastian
ID - 9307
JF - Stochastics and Partial Differential Equations: Analysis and Computations
SN - 21940401
TI - Finite time extinction for the 1D stochastic porous medium equation with transport noise
ER -
TY - JOUR
AB - The high processing cost, poor mechanical properties and moderate performance of Bi2Te3âbased alloys used in thermoelectric devices limit the cost-effectiveness of this energy conversion technology. Towards solving these current challenges, in the present work, we detail a low temperature solution-based approach to produce Bi2Te3-Cu2-xTe nanocomposites with improved thermoelectric performance. Our approach consists in combining proper ratios of colloidal nanoparticles and to consolidate the resulting mixture into nanocomposites using a hot press. The transport properties of the nanocomposites are characterized and compared with those of pure Bi2Te3 nanomaterials obtained following the same procedure. In contrast with most previous works, the presence of Cu2-xTe nanodomains does not result in a significant reduction of the lattice thermal conductivity of the reference Bi2Te3 nanomaterial, which is already very low. However, the introduction of Cu2-xTe yields a nearly threefold increase of the power factor associated to a simultaneous increase of the Seebeck coefficient and electrical conductivity at temperatures above 400 K. Taking into account the band alignment of the two materials, we rationalize this increase by considering that Cu2-xTe nanostructures, with a relatively low electron affinity, are able to inject electrons into Bi2Te3, enhancing in this way its electrical conductivity. The simultaneous increase of the Seebeck coefficient is related to the energy filtering of charge carriers at energy barriers within Bi2Te3 domains associated with the accumulation of electrons in regions nearby a Cu2-xTe/Bi2Te3 heterojunction. Overall, with the incorporation of a proper amount of Cu2-xTe nanoparticles, we demonstrate a 250% improvement of the thermoelectric figure of merit of Bi2Te3.
AU - Zhang, Yu
AU - Xing, Congcong
AU - Liu, Yu
AU - Li, Mengyao
AU - Xiao, Ke
AU - Guardia, Pablo
AU - Lee, Seungho
AU - Han, Xu
AU - Ostovari Moghaddam, Ahmad
AU - Josep Roa, Joan
AU - Arbiol, Jordi
AU - IbĂĄĂ±ez, Maria
AU - Pan, Kai
AU - Prato, Mirko
AU - Xie, Ying
AU - Cabot, Andreu
ID - 9304
IS - 8
JF - Chemical Engineering Journal
SN - 13858947
TI - Influence of copper telluride nanodomains on the transport properties of n-type bismuth telluride
VL - 418
ER -
TY - JOUR
AB - Several Ising-type magnetic van der Waals (vdW) materials exhibit stable magnetic ground states. Despite these clear experimental demonstrations, a complete theoretical and microscopic understanding of their magnetic anisotropy is still lacking. In particular, the validity limit of identifying their one-dimensional (1-D) Ising nature has remained uninvestigated in a quantitative way. Here we performed the complete mapping of magnetic anisotropy for a prototypical Ising vdW magnet FePS3 for the first time. Combining torque magnetometry measurements with their magnetostatic model analysis and the relativistic density functional total energy calculations, we successfully constructed the three-dimensional (3-D) mappings of the magnetic anisotropy in terms of magnetic torque and energy. The results not only quantitatively confirm that the easy axis is perpendicular to the ab plane, but also reveal the anisotropies within the ab, ac, and bc planes. Our approach can be applied to the detailed quantitative study of magnetism in vdW materials.
AU - Nauman, Muhammad
AU - Kiem, Do Hoon
AU - Lee, Sungmin
AU - Son, Suhan
AU - Park, J-G
AU - Kang, Woun
AU - Han, Myung Joon
AU - Jo, Youn Jung
ID - 9282
JF - 2D Materials
KW - Mechanical Engineering
KW - General Materials Science
KW - Mechanics of Materials
KW - General Chemistry
KW - Condensed Matter Physics
SN - 2053-1583
TI - Complete mapping of magnetic anisotropy for prototype Ising van der Waals FePS3
ER -
TY - JOUR
AB - Assemblies of actin and its regulators underlie the dynamic morphology of all eukaryotic cells. To understand how actin regulatory proteins work together to generate actin-rich structures such as filopodia, we analyzed the localization of diverse actin regulators within filopodia in Drosophila embryos and in a complementary in vitro system of filopodia-like structures (FLSs). We found that the composition of the regulatory protein complex where actin is incorporated (the filopodial tip complex) is remarkably heterogeneous both in vivo and in vitro. Our data reveal that different pairs of proteins correlate with each other and with actin bundle length, suggesting the presence of functional subcomplexes. This is consistent with a theoretical framework where three or more redundant subcomplexes join the tip complex stochastically, with any two being sufficient to drive filopodia formation. We provide an explanation for the observed heterogeneity and suggest that a mechanism based on multiple components allows stereotypical filopodial dynamics to arise from diverse upstream signaling pathways.
AU - Dobramysl, Ulrich
AU - Jarsch, Iris Katharina
AU - Inoue, Yoshiko
AU - Shimo, Hanae
AU - Richier, Benjamin
AU - Gadsby, Jonathan R.
AU - Mason, Julia
AU - SzaĆapak, Alicja
AU - Ioannou, Pantelis Savvas
AU - Correia, Guilherme Pereira
AU - Walrant, Astrid
AU - Butler, Richard
AU - Hannezo, Edouard B
AU - Simons, Benjamin D.
AU - Gallop, Jennifer L.
ID - 9306
IS - 4
JF - The Journal of Cell Biology
TI - Stochastic combinations of actin regulatory proteins are sufficient to drive filopodia formation
VL - 220
ER -
TY - JOUR
AB - Copper chalcogenides are outstanding thermoelectric materials for applications in the medium-high temperature range. Among different chalcogenides, while Cu2âxSe is characterized by higher thermoelectric figures of merit, Cu2âxS provides advantages in terms of low cost and element abundance. In the present work, we investigate the effect of different dopants to enhance the Cu2âxS performance and also its thermal stability. Among the tested options, Pb-doped Cu2âxS shows the highest improvement in stability against sulfur volatilization. Additionally, Pb incorporation allows tuning charge carrier concentration, which enables a significant improvement of the power factor. We demonstrate here that the introduction of an optimal additive amount of just 0.3% results in a threefold increase of the power factor in the middle-temperature range (500â800 K) and a record dimensionless thermoelectric figure of merit above 2 at 880 K.
AU - Zhang, Yu
AU - Xing, Congcong
AU - Liu, Yu
AU - Spadaro, Maria Chiara
AU - Wang, Xiang
AU - Li, Mengyao
AU - Xiao, Ke
AU - Zhang, Ting
AU - Guardia, Pablo
AU - Lim, Khak Ho
AU - Moghaddam, Ahmad Ostovari
AU - Llorca, Jordi
AU - Arbiol, Jordi
AU - IbĂĄĂ±ez, Maria
AU - Cabot, Andreu
ID - 9305
IS - 7
JF - Nano Energy
SN - 22112855
TI - Doping-mediated stabilization of copper vacancies to promote thermoelectric properties of Cu2-xS
VL - 85
ER -
TY - JOUR
AB - Embryo morphogenesis is impacted by dynamic changes in tissue material properties, which have been proposed to occur via processes akin to phase transitions (PTs). Here, we show that rigidity percolation provides a simple and robust theoretical framework to predict material/structural PTs of embryonic tissues from local cell connectivity. By using percolation theory, combined with directly monitoring dynamic changes in tissue rheology and cell contact mechanics, we demonstrate that the zebrafish blastoderm undergoes a genuine rigidity PT, brought about by a small reduction in adhesion-dependent cell connectivity below a critical value. We quantitatively predict and experimentally verify hallmarks of PTs, including power-law exponents and associated discontinuities of macroscopic observables. Finally, we show that this uniform PT depends on blastoderm cells undergoing meta-synchronous divisions causing random and, consequently, uniform changes in cell connectivity. Collectively, our theoretical and experimental findings reveal the structural basis of material PTs in an organismal context.
AU - Petridou, Nicoletta
AU - Corominas-Murtra, Bernat
AU - Heisenberg, Carl-Philipp J
AU - Hannezo, Edouard B
ID - 9316
IS - 7
JF - Cell
SN - 00928674
TI - Rigidity percolation uncovers a structural basis for embryonic tissue phase transitions
VL - 184
ER -
TY - JOUR
AB - Partially observable Markov decision processes (POMDPs) are standard models for dynamic systems with probabilistic and nondeterministic behaviour in uncertain environments. We prove that in POMDPs with long-run average objective, the decision maker has approximately optimal strategies with finite memory. This implies notably that approximating the long-run value is recursively enumerable, as well as a weak continuity property of the value with respect to the transition function.
AU - Chatterjee, Krishnendu
AU - Saona Urmeneta, Raimundo J
AU - Ziliotto, Bruno
ID - 9311
JF - Mathematics of Operations Research
KW - Management Science and Operations Research
KW - General Mathematics
KW - Computer Science Applications
SN - 0364-765X
TI - Finite-memory strategies in POMDPs with long-run average objectives
ER -
TY - JOUR
AB - We consider inertial iteration methods for FermatâWeber location problem and primalâdual three-operator splitting in real Hilbert spaces. To do these, we first obtain weak convergence analysis and nonasymptotic O(1/n) convergence rate of the inertial KrasnoselskiiâMann iteration for fixed point of nonexpansive operators in infinite dimensional real Hilbert spaces under some seemingly easy to implement conditions on the iterative parameters. One of our contributions is that the convergence analysis and rate of convergence results are obtained using conditions which appear not complicated and restrictive as assumed in other previous related results in the literature. We then show that FermatâWeber location problem and primalâdual three-operator splitting are special cases of fixed point problem of nonexpansive mapping and consequently obtain the convergence analysis of inertial iteration methods for FermatâWeber location problem and primalâdual three-operator splitting in real Hilbert spaces. Some numerical implementations are drawn from primalâdual three-operator splitting to support the theoretical analysis.
AU - Iyiola, Olaniyi S.
AU - Shehu, Yekini
ID - 9315
IS - 2
JF - Results in Mathematics
SN - 14226383
TI - New convergence results for inertial KrasnoselskiiâMann iterations in Hilbert spaces with applications
VL - 76
ER -
TY - JOUR
AB - The leaf is a crucial organ evolved with remarkable morphological diversity to maximize plant photosynthesis. The leaf shape is a key trait that affects photosynthesis, flowering rates, disease resistance, and yield. Although many genes regulating leaf development have been identified in the past years, the precise regulatory architecture underlying the generation of diverse leaf shapes remains to be elucidated. We used cotton as a reference model to probe the genetic framework underlying divergent leaf forms. Comparative transcriptome analysis revealed that the GhARF16â1 and GhKNOX2â1 genes might be potential regulators of leaf shape. We functionally characterized the auxinâresponsive factor ARF16â1 acting upstream of GhKNOX2â1 to determine leaf morphology in cotton. The transcription of GhARF16â1 was significantly higher in lobedâleaved cotton than in smoothâleaved cotton. Furthermore, the overexpression of GhARF16â1 led to the upregulation of GhKNOX2â1 and resulted in more and deeper serrations in cotton leaves, similar to the leaf shape of cotton plants overexpressing GhKNOX2â1. We found that GhARF16â1 specifically bound to the promoter of GhKNOX2â1 to induce its expression. The heterologous expression of GhARF16â1 and GhKNOX2â1 in Arabidopsis led to lobed and curly leaves, and a genetic analysis revealed that GhKNOX2â1 is epistatic to GhARF16â1 in Arabidopsis, suggesting that the GhARF16â1 and GhKNOX2â1 interaction paradigm also functions to regulate leaf shape in Arabidopsis. To our knowledge, our results uncover a novel mechanism by which auxin, through the key component ARF16â1 and its downstreamâactivated gene KNOX2â1, determines leaf morphology in eudicots.
AU - He, P
AU - Zhang, Yuzhou
AU - Li, H
AU - Fu, X
AU - Shang, H
AU - Zou, C
AU - Friml, JiĆĂ
AU - Xiao, G
ID - 8606
IS - 3
JF - Plant Biotechnology Journal
SN - 1467-7644
TI - GhARF16-1 modulates leaf development by transcriptionally regulating the GhKNOX2-1 gene in cotton
VL - 19
ER -
TY - JOUR
AB - Collective cell migration offers a rich field of study for non-equilibrium physics and cellular biology, revealing phenomena such as glassy dynamics, pattern formation and active turbulence. However, how mechanical and chemical signalling are integrated at the cellular level to give rise to such collective behaviours remains unclear. We address this by focusing on the highly conserved phenomenon of spatiotemporal waves of density and extracellular signal-regulated kinase (ERK) activation, which appear both in vitro and in vivo during collective cell migration and wound healing. First, we propose a biophysical theory, backed by mechanical and optogenetic perturbation experiments, showing that patterns can be quantitatively explained by a mechanochemical coupling between active cellular tensions and the mechanosensitive ERK pathway. Next, we demonstrate how this biophysical mechanism can robustly induce long-ranged order and migration in a desired orientation, and we determine the theoretically optimal wavelength and period for inducing maximal migration towards free edges, which fits well with experimentally observed dynamics. We thereby provide a bridge between the biophysical origin of spatiotemporal instabilities and the design principles of robust and efficient long-ranged migration.
AU - Boocock, Daniel R
AU - Hino, Naoya
AU - Ruzickova, Natalia
AU - Hirashima, Tsuyoshi
AU - Hannezo, Edouard B
ID - 8602
JF - Nature Physics
SN - 17452473
TI - Theory of mechanochemical patterning and optimal migration in cell monolayers
VL - 17
ER -
TY - JOUR
AB - The Mytilus complex of marine mussel species forms a mosaic of hybrid zones, found across temperate regions of the globe. This allows us to study âreplicatedâ instances of secondary contact between closely related species. Previous work on this complex has shown that local introgression is both widespread and highly heterogeneous, and has identified SNPs that are outliers of differentiation between lineages. Here, we developed an ancestryâinformative panel of such SNPs. We then compared their frequencies in newly sampled populations, including samples from within the hybrid zones, and parental populations at different distances from the contact. Results show that close to the hybrid zones, some outlier loci are near to fixation for the heterospecific allele, suggesting enhanced local introgression, or the local sweep of a shared ancestral allele. Conversely, genomic cline analyses, treating local parental populations as the reference, reveal a globally high concordance among loci, albeit with a few signals of asymmetric introgression. Enhanced local introgression at specific loci is consistent with the early transfer of adaptive variants after contact, possibly including asymmetric biâstable variants (DobzhanskyâMuller incompatibilities), or haplotypes loaded with fewer deleterious mutations. Having escaped one barrier, however, these variants can be trapped or delayed at the next barrier, confining the introgression locally. These results shed light on the decay of species barriers during phases of contact.
AU - Simon, Alexis
AU - Fraisse, Christelle
AU - El Ayari, Tahani
AU - LiautardâHaag, Cathy
AU - Strelkov, Petr
AU - Welch, John J
AU - Bierne, Nicolas
ID - 8708
IS - 1
JF - Journal of Evolutionary Biology
SN - 1010061X
TI - How do species barriers decay? Concordance and local introgression in mosaic hybrid zones of mussels
VL - 34
ER -
TY - JOUR
AB - The synaptotrophic hypothesis posits that synapse formation stabilizes dendritic branches, yet this hypothesis has not been causally tested in vivo in the mammalian brain. Presynaptic ligand cerebellin-1 (Cbln1) and postsynaptic receptor GluD2 mediate synaptogenesis between granule cells and Purkinje cells in the molecular layer of the cerebellar cortex. Here we show that sparse but not global knockout of GluD2 causes under-elaboration of Purkinje cell dendrites in the deep molecular layer and overelaboration in the superficial molecular layer. Developmental, overexpression, structure-function, and genetic epistasis analyses indicate that dendrite morphogenesis defects result from competitive synaptogenesis in a Cbln1/GluD2-dependent manner. A generative model of dendritic growth based on competitive synaptogenesis largely recapitulates GluD2 sparse and global knockout phenotypes. Our results support the synaptotrophic hypothesis at initial stages of dendrite development, suggest a second mode in which cumulative synapse formation inhibits further dendrite growth, and highlight the importance of competition in dendrite morphogenesis.
AU - Takeo, Yukari H.
AU - Shuster, S. Andrew
AU - Jiang, Linnie
AU - Hu, Miley
AU - Luginbuhl, David J.
AU - RĂŒlicke, Thomas
AU - Contreras, Ximena
AU - Hippenmeyer, Simon
AU - Wagner, Mark J.
AU - Ganguli, Surya
AU - Luo, Liqun
ID - 8544
IS - 4
JF - Neuron
TI - GluD2- and Cbln1-mediated competitive synaptogenesis shapes the dendritic arbors of cerebellar Purkinje cells
VL - 109
ER -
TY - JOUR
AB - We consider a system of N bosons in the mean-field scaling regime for a class of interactions including the repulsive Coulomb potential. We derive an asymptotic expansion of the low-energy eigenstates and the corresponding energies, which provides corrections to Bogoliubov theory to any order in 1/N.
AU - Bossmann, Lea
AU - Petrat, SĂ¶ren P
AU - Seiringer, Robert
ID - 9318
JF - Forum of Mathematics, Sigma
TI - Asymptotic expansion of low-energy excitations for weakly interacting bosons
VL - 9
ER -
TY - JOUR
AB - In RuCl3, inelastic neutron scattering and Raman spectroscopy reveal a continuum of non-spin-wave excitations that persists to high temperature, suggesting the presence of a spin liquid state on a honeycomb lattice. In the context of the Kitaev model, finite magnetic fields introduce interactions between the elementary excitations, and thus the effects of high magnetic fields that are comparable to the spin-exchange energy scale must be explored. Here, we report measurements of the magnetotropic coefficientâthe thermodynamic coefficient associated with magnetic anisotropyâover a wide range of magnetic fields and temperatures. We find that magnetic field and temperature compete to determine the magnetic response in a way that is independent of the large intrinsic exchange-interaction energy. This emergent scale-invariant magnetic anisotropy provides evidence for a high degree of exchange frustration that favours the formation of a spin liquid state in RuCl3.
AU - Modic, Kimberly A
AU - McDonald, Ross D.
AU - Ruff, J.P.C.
AU - Bachmann, Maja D.
AU - Lai, You
AU - Palmstrom, Johanna C.
AU - Graf, David
AU - Chan, Mun K.
AU - Balakirev, F.F.
AU - Betts, J.B.
AU - Boebinger, G.S.
AU - Schmidt, Marcus
AU - Lawler, Michael J.
AU - Sokolov, D.A.
AU - Moll, Philip J.W.
AU - Ramshaw, B.J.
AU - Shekhter, Arkady
ID - 8673
JF - Nature Physics
SN - 17452473
TI - Scale-invariant magnetic anisotropy in RuCl3 at high magnetic fields
VL - 17
ER -
TY - JOUR
AB - Given a locally finite XâRd and a radius râ„0, the k-fold cover of X and r consists of all points in Rd that have k or more points of X within distance r. We consider two filtrationsâone in scale obtained by fixing k and increasing r, and the other in depth obtained by fixing r and decreasing kâand we compute the persistence diagrams of both. While standard methods suffice for the filtration in scale, we need novel geometric and topological concepts for the filtration in depth. In particular, we introduce a rhomboid tiling in Rd+1 whose horizontal integer slices are the order-k Delaunay mosaics of X, and construct a zigzag module of Delaunay mosaics that is isomorphic to the persistence module of the multi-covers.
AU - Edelsbrunner, Herbert
AU - Osang, Georg F
ID - 9317
JF - Discrete and Computational Geometry
SN - 01795376
TI - The multi-cover persistence of Euclidean balls
ER -
TY - JOUR
AB - For automata, synchronization, the problem of bringing an automaton to a particular state regardless of its initial state, is important. It has several applications in practice and is related to a fifty-year-old conjecture on the length of the shortest synchronizing word. Although using shorter words increases the effectiveness in practice, finding a shortest one (which is not necessarily unique) is NP-hard. For this reason, there exist various heuristics in the literature. However, high-quality heuristics such as SynchroP producing relatively shorter sequences are very expensive and can take hours when the automaton has tens of thousands of states. The SynchroP heuristic has been frequently used as a benchmark to evaluate the performance of the new heuristics. In this work, we first improve the runtime of SynchroP and its variants by using algorithmic techniques. We then focus on adapting SynchroP for many-core architectures,
and overall, we obtain more than 1000Ă speedup on GPUs compared to naive sequential implementation that has been frequently used as a benchmark to evaluate new heuristics in the literature. We also propose two SynchroP variants and evaluate their performance.
AU - Sarac, Naci E
AU - Altun, Ămer Faruk
AU - Atam, Kamil Tolga
AU - Karahoda, Sertac
AU - Kaya, Kamer
AU - YenigĂŒn, HĂŒsnĂŒ
ID - 8912
IS - 4
JF - Expert Systems with Applications
SN - 09574174
TI - Boosting expensive synchronizing heuristics
VL - 167
ER -
TY - JOUR
AB - Domestication is a humanâinduced selection process that imprints the genomes of domesticated populations over a short evolutionary time scale and that occurs in a given demographic context. Reconstructing historical gene flow, effective population size changes and their timing is therefore of fundamental interest to understand how plant demography and human selection jointly shape genomic divergence during domestication. Yet, the comparison under a single statistical framework of independent domestication histories across different crop species has been little evaluated so far. Thus, it is unclear whether domestication leads to convergent demographic changes that similarly affect crop genomes. To address this question, we used existing and new transcriptome data on three crop species of Solanaceae (eggplant, pepper and tomato), together with their close wild relatives. We fitted twelve demographic models of increasing complexity on the unfolded joint allele frequency spectrum for each wild/crop pair, and we found evidence for both shared and speciesâspecific demographic processes between species. A convergent history of domestication with gene flow was inferred for all three species, along with evidence of strong reduction in the effective population size during the cultivation stage of tomato and pepper. The absence of any reduction in size of the crop in eggplant stands out from the classical view of the domestication process; as does the existence of a âprotracted periodâ of management before cultivation. Our results also suggest divergent management strategies of modern cultivars among species as their current demography substantially differs. Finally, the timing of domestication is speciesâspecific and supported by the few historical records available.
AU - Arnoux, StĂ©phanie
AU - Fraisse, Christelle
AU - Sauvage, Christopher
ID - 8928
IS - 2
JF - Journal of Evolutionary Biology
SN - 1010061X
TI - Genomic inference of complex domestication histories in three Solanaceae species
VL - 34
ER -