[{"author":[{"last_name":"Lemeshko","first_name":"Mikhail","orcid":"0000-0002-6990-7802","id":"37CB05FA-F248-11E8-B48F-1D18A9856A87","full_name":"Mikhail Lemeshko"}],"date_created":"2018-12-11T11:56:17Z","date_updated":"2021-01-12T06:55:55Z","volume":83,"year":"2011","_id":"2198","publication_status":"published","title":"Shaping interactions between polar molecules with far-off-resonant light","status":"public","intvolume":" 83","publisher":"American Physical Society","abstract":[{"text":"We show that dressing polar molecules with a far-off-resonant optical field leads to new types of intermolecular potentials, which undergo a crossover from the inverse power to oscillating behavior depending on the intermolecular distance, and whose parameters can be tuned by varying the laser intensity and wavelength. We present analytic expressions for the potential energy surfaces, thereby providing direct access to the parameters of an optical field required to design intermolecular interactions experimentally.","lang":"eng"}],"issue":"5","publist_id":"4775","extern":1,"type":"journal_article","date_published":"2011-05-27T00:00:00Z","doi":"10.1103/PhysRevA.83.051402","publication":"Physical Review A - Atomic, Molecular, and Optical Physics","citation":{"ieee":"M. Lemeshko, “Shaping interactions between polar molecules with far-off-resonant light,” Physical Review A - Atomic, Molecular, and Optical Physics, vol. 83, no. 5. American Physical Society, 2011.","apa":"Lemeshko, M. (2011). Shaping interactions between polar molecules with far-off-resonant light. Physical Review A - Atomic, Molecular, and Optical Physics. American Physical Society. https://doi.org/10.1103/PhysRevA.83.051402","ista":"Lemeshko M. 2011. Shaping interactions between polar molecules with far-off-resonant light. Physical Review A - Atomic, Molecular, and Optical Physics. 83(5).","ama":"Lemeshko M. Shaping interactions between polar molecules with far-off-resonant light. Physical Review A - Atomic, Molecular, and Optical Physics. 2011;83(5). doi:10.1103/PhysRevA.83.051402","chicago":"Lemeshko, Mikhail. “Shaping Interactions between Polar Molecules with Far-off-Resonant Light.” Physical Review A - Atomic, Molecular, and Optical Physics. American Physical Society, 2011. https://doi.org/10.1103/PhysRevA.83.051402.","short":"M. Lemeshko, Physical Review A - Atomic, Molecular, and Optical Physics 83 (2011).","mla":"Lemeshko, Mikhail. “Shaping Interactions between Polar Molecules with Far-off-Resonant Light.” Physical Review A - Atomic, Molecular, and Optical Physics, vol. 83, no. 5, American Physical Society, 2011, doi:10.1103/PhysRevA.83.051402."},"main_file_link":[{"url":"http://arxiv.org/abs/1104.1046","open_access":"1"}],"oa":1,"quality_controlled":0,"month":"05","day":"27"},{"month":"01","day":"01","quality_controlled":0,"page":"70 - 79","publication":"Cell","citation":{"short":"G. Novarino, N. Akizu, J. Gleeson, Cell 147 (2011) 70–79.","mla":"Novarino, Gaia, et al. “Modeling Human Disease in Humans: The Ciliopathies.” Cell, vol. 147, no. 1, Cell Press, 2011, pp. 70–79, doi:10.1016/j.cell.2011.09.014.","chicago":"Novarino, Gaia, Naiara Akizu, and Joseph Gleeson. “Modeling Human Disease in Humans: The Ciliopathies.” Cell. Cell Press, 2011. https://doi.org/10.1016/j.cell.2011.09.014.","ama":"Novarino G, Akizu N, Gleeson J. Modeling human disease in humans: The ciliopathies. Cell. 2011;147(1):70-79. doi:10.1016/j.cell.2011.09.014","ieee":"G. Novarino, N. Akizu, and J. Gleeson, “Modeling human disease in humans: The ciliopathies,” Cell, vol. 147, no. 1. Cell Press, pp. 70–79, 2011.","apa":"Novarino, G., Akizu, N., & Gleeson, J. (2011). Modeling human disease in humans: The ciliopathies. Cell. Cell Press. https://doi.org/10.1016/j.cell.2011.09.014","ista":"Novarino G, Akizu N, Gleeson J. 2011. Modeling human disease in humans: The ciliopathies. Cell. 147(1), 70–79."},"doi":"10.1016/j.cell.2011.09.014","date_published":"2011-01-01T00:00:00Z","type":"review","extern":1,"abstract":[{"lang":"eng","text":"Soon, the genetic basis of most human Mendelian diseases will be solved. The next challenge will be to leverage this information to uncover basic mechanisms of disease and develop new therapies. To understand how this transformation is already beginning to unfold, we focus on the ciliopathies, a class of multi-organ diseases caused by disruption of the primary cilium. Through a convergence of data involving mutant gene discovery, proteomics, and cell biology, more than a dozen phenotypically distinguishable conditions are now united as ciliopathies. Sitting at the interface between simple and complex genetic conditions, these diseases provide clues to the future direction of human genetics."}],"issue":"1","publist_id":"4615","publication_status":"published","title":"Modeling human disease in humans: The ciliopathies","status":"public","publisher":"Cell Press","intvolume":" 147","year":"2011","_id":"2312","date_created":"2018-12-11T11:56:55Z","date_updated":"2019-04-26T07:22:10Z","volume":147,"author":[{"orcid":"0000-0002-7673-7178","id":"3E57A680-F248-11E8-B48F-1D18A9856A87","last_name":"Novarino","first_name":"Gaia","full_name":"Gaia Novarino"},{"full_name":"Akizu, Naiara","first_name":"Naiara","last_name":"Akizu"},{"last_name":"Gleeson","first_name":"Joseph","full_name":"Gleeson, Joseph G"}]},{"date_created":"2018-12-11T11:56:58Z","date_updated":"2021-01-12T06:56:45Z","author":[{"last_name":"Frank","first_name":"Rupert","full_name":"Frank, Rupert L"},{"full_name":"Lieb, Élliott H","first_name":"Élliott","last_name":"Lieb"},{"first_name":"Robert","last_name":"Seiringer","id":"4AFD0470-F248-11E8-B48F-1D18A9856A87","orcid":"0000-0002-6781-0521","full_name":"Robert Seiringer"},{"first_name":"Lawrence","last_name":"Thomas","full_name":"Thomas, Lawrence E"}],"publisher":"World Scientific Publishing","publication_status":"published","title":"Binding, stability, and non-binding of multi-polaron systems","status":"public","year":"2011","_id":"2320","extern":1,"publist_id":"4607","abstract":[{"text":"The binding of polarons, or its absence, is an old and subtle topic. After defining the model we state some recent theorems of ours. First, the transition from many-body collapse to the existence of a thermodynamic limit for N polarons occurs precisely at U = 2α, where U is the electronic Coulomb repulsion and α is the polaron coupling constant. Second, if U is large enough, there is no multi-polaron binding of any kind. We also discuss the Pekar-Tomasevich approximation to the ground state energy, which is valid for large α. Finally, we derive exact results, not reported before, about the one-dimensional toy model introduced by E. P. Gross.","lang":"eng"}],"type":"conference","date_published":"2011-05-26T00:00:00Z","doi":"10.1142/9789814350365_0002","conference":{"name":"QMath: Mathematical Results in Quantum Physics"},"page":"21 - 32","quality_controlled":0,"citation":{"ama":"Frank R, Lieb É, Seiringer R, Thomas L. Binding, stability, and non-binding of multi-polaron systems. In: World Scientific Publishing; 2011:21-32. doi:10.1142/9789814350365_0002","ieee":"R. Frank, É. Lieb, R. Seiringer, and L. Thomas, “Binding, stability, and non-binding of multi-polaron systems,” presented at the QMath: Mathematical Results in Quantum Physics, 2011, pp. 21–32.","apa":"Frank, R., Lieb, É., Seiringer, R., & Thomas, L. (2011). Binding, stability, and non-binding of multi-polaron systems (pp. 21–32). Presented at the QMath: Mathematical Results in Quantum Physics, World Scientific Publishing. https://doi.org/10.1142/9789814350365_0002","ista":"Frank R, Lieb É, Seiringer R, Thomas L. 2011. Binding, stability, and non-binding of multi-polaron systems. QMath: Mathematical Results in Quantum Physics, 21–32.","short":"R. Frank, É. Lieb, R. Seiringer, L. Thomas, in:, World Scientific Publishing, 2011, pp. 21–32.","mla":"Frank, Rupert, et al. Binding, Stability, and Non-Binding of Multi-Polaron Systems. World Scientific Publishing, 2011, pp. 21–32, doi:10.1142/9789814350365_0002.","chicago":"Frank, Rupert, Élliott Lieb, Robert Seiringer, and Lawrence Thomas. “Binding, Stability, and Non-Binding of Multi-Polaron Systems,” 21–32. World Scientific Publishing, 2011. https://doi.org/10.1142/9789814350365_0002."},"main_file_link":[{"url":"http://arxiv.org/abs/1010.0737","open_access":"1"}],"oa":1,"month":"05","day":"26"},{"abstract":[{"lang":"eng","text":"We derive a sharp bound on the location of non-positive eigenvalues of Schrödinger operators on the half-line with complex-valued potentials."}],"publist_id":"4606","extern":1,"type":"conference","alternative_title":["Operator Theory: Advances and Applications"],"author":[{"first_name":"Rupert","last_name":"Frank","full_name":"Frank, Rupert L"},{"last_name":"Laptev","first_name":"Ari","full_name":"Laptev, Ari"},{"full_name":"Robert Seiringer","last_name":"Seiringer","first_name":"Robert","orcid":"0000-0002-6781-0521","id":"4AFD0470-F248-11E8-B48F-1D18A9856A87"}],"date_created":"2018-12-11T11:56:59Z","date_updated":"2021-01-12T06:56:46Z","volume":214,"year":"2011","_id":"2321","publication_status":"published","status":"public","title":" A sharp bound on eigenvalues of Schrödinger operators on the halfline with complex-valued potentials","intvolume":" 214","publisher":"Springer","day":"31","month":"03","conference":{"name":"OTAMP: Operator Theory, Analysis and Mathematical Physics"},"date_published":"2011-03-31T00:00:00Z","doi":"10.1007/978-3-7643-9994-8_3","oa":1,"citation":{"chicago":"Frank, Rupert, Ari Laptev, and Robert Seiringer. “ A Sharp Bound on Eigenvalues of Schrödinger Operators on the Halfline with Complex-Valued Potentials,” 214:39–44. Springer, 2011. https://doi.org/10.1007/978-3-7643-9994-8_3.","mla":"Frank, Rupert, et al. A Sharp Bound on Eigenvalues of Schrödinger Operators on the Halfline with Complex-Valued Potentials. Vol. 214, Springer, 2011, pp. 39–44, doi:10.1007/978-3-7643-9994-8_3.","short":"R. Frank, A. Laptev, R. Seiringer, in:, Springer, 2011, pp. 39–44.","ista":"Frank R, Laptev A, Seiringer R. 2011. A sharp bound on eigenvalues of Schrödinger operators on the halfline with complex-valued potentials. OTAMP: Operator Theory, Analysis and Mathematical Physics, Operator Theory: Advances and Applications, vol. 214, 39–44.","ieee":"R. Frank, A. Laptev, and R. Seiringer, “ A sharp bound on eigenvalues of Schrödinger operators on the halfline with complex-valued potentials,” presented at the OTAMP: Operator Theory, Analysis and Mathematical Physics, 2011, vol. 214, pp. 39–44.","apa":"Frank, R., Laptev, A., & Seiringer, R. (2011). A sharp bound on eigenvalues of Schrödinger operators on the halfline with complex-valued potentials (Vol. 214, pp. 39–44). Presented at the OTAMP: Operator Theory, Analysis and Mathematical Physics, Springer. https://doi.org/10.1007/978-3-7643-9994-8_3","ama":"Frank R, Laptev A, Seiringer R. A sharp bound on eigenvalues of Schrödinger operators on the halfline with complex-valued potentials. In: Vol 214. Springer; 2011:39-44. doi:10.1007/978-3-7643-9994-8_3"},"main_file_link":[{"url":"http://arxiv.org/abs/0903.2053","open_access":"1"}],"quality_controlled":0,"page":"39 - 44"},{"quality_controlled":0,"page":"139 - 150","publication":"Archiv der Mathematik","citation":{"chicago":"Browning, Timothy D. “Power-Free Values of Polynomials.” Archiv Der Mathematik. Birkhäuser, 2011. https://doi.org/10.1007/s00013-011-0224-7.","short":"T.D. Browning, Archiv Der Mathematik 96 (2011) 139–150.","mla":"Browning, Timothy D. “Power-Free Values of Polynomials.” Archiv Der Mathematik, vol. 96, no. 2, Birkhäuser, 2011, pp. 139–50, doi:10.1007/s00013-011-0224-7.","apa":"Browning, T. D. (2011). Power-free values of polynomials. Archiv Der Mathematik. Birkhäuser. https://doi.org/10.1007/s00013-011-0224-7","ieee":"T. D. Browning, “Power-free values of polynomials,” Archiv der Mathematik, vol. 96, no. 2. Birkhäuser, pp. 139–150, 2011.","ista":"Browning TD. 2011. Power-free values of polynomials. Archiv der Mathematik. 96(2), 139–150.","ama":"Browning TD. Power-free values of polynomials. Archiv der Mathematik. 2011;96(2):139-150. doi:10.1007/s00013-011-0224-7"},"doi":"10.1007/s00013-011-0224-7","date_published":"2011-02-19T00:00:00Z","day":"19","month":"02","publication_status":"published","title":"Power-free values of polynomials","status":"public","intvolume":" 96","publisher":"Birkhäuser","_id":"233","acknowledgement":"EP/E053262/1\tEngineering and Physical Sciences Research Council","year":"2011","date_updated":"2021-01-12T06:56:49Z","date_created":"2018-12-11T11:45:21Z","volume":96,"author":[{"orcid":"0000-0002-8314-0177","id":"35827D50-F248-11E8-B48F-1D18A9856A87","last_name":"Browning","first_name":"Timothy D","full_name":"Timothy Browning"}],"type":"journal_article","extern":1,"abstract":[{"lang":"eng","text":"For an irreducible polynomial in at most two variables the problem of representing power-free integers is investigated. "}],"publist_id":"7670","issue":"2"},{"page":"579 - 602","quality_controlled":0,"citation":{"apa":"Browning, T. D. (2011). The divisor problem for binary cubic forms. Journal de Theorie Des Nombres de Bordeaux. Universite de Bordeaux. https://doi.org/10.5802/jtnb.778","ieee":"T. D. Browning, “The divisor problem for binary cubic forms,” Journal de Theorie des Nombres de Bordeaux, vol. 23, no. 3. Universite de Bordeaux, pp. 579–602, 2011.","ista":"Browning TD. 2011. The divisor problem for binary cubic forms. Journal de Theorie des Nombres de Bordeaux. 23(3), 579–602.","ama":"Browning TD. The divisor problem for binary cubic forms. Journal de Theorie des Nombres de Bordeaux. 2011;23(3):579-602. doi:10.5802/jtnb.778","chicago":"Browning, Timothy D. “The Divisor Problem for Binary Cubic Forms.” Journal de Theorie Des Nombres de Bordeaux. Universite de Bordeaux, 2011. https://doi.org/10.5802/jtnb.778.","short":"T.D. Browning, Journal de Theorie Des Nombres de Bordeaux 23 (2011) 579–602.","mla":"Browning, Timothy D. “The Divisor Problem for Binary Cubic Forms.” Journal de Theorie Des Nombres de Bordeaux, vol. 23, no. 3, Universite de Bordeaux, 2011, pp. 579–602, doi:10.5802/jtnb.778."},"publication":"Journal de Theorie des Nombres de Bordeaux","date_published":"2011-01-01T00:00:00Z","doi":"10.5802/jtnb.778","month":"01","day":"01","publisher":"Universite de Bordeaux","intvolume":" 23","status":"public","title":"The divisor problem for binary cubic forms","publication_status":"published","_id":"234","year":"2011","volume":23,"date_updated":"2021-01-12T06:56:53Z","date_created":"2018-12-11T11:45:21Z","author":[{"full_name":"Timothy Browning","id":"35827D50-F248-11E8-B48F-1D18A9856A87","orcid":"0000-0002-8314-0177","first_name":"Timothy D","last_name":"Browning"}],"type":"journal_article","extern":1,"issue":"3","publist_id":"7671","abstract":[{"lang":"eng","text":"We investigate the average order of the divisor function at values of binary cubic forms that are reducible over Q and discuss some applications."}]},{"date_published":"2011-07-01T00:00:00Z","language":[{"iso":"eng"}],"publication":"Illinois Journal of Mathematics","citation":{"ieee":"T. D. Browning and C. Elsholtz, “The number of representations of rationals as a sum of unit fractions,” Illinois Journal of Mathematics, vol. 55, no. 2. University of Illinois Press, pp. 685–696, 2011.","apa":"Browning, T. D., & Elsholtz, C. (2011). The number of representations of rationals as a sum of unit fractions. Illinois Journal of Mathematics. University of Illinois Press.","ista":"Browning TD, Elsholtz C. 2011. The number of representations of rationals as a sum of unit fractions. Illinois Journal of Mathematics. 55(2), 685–696.","ama":"Browning TD, Elsholtz C. The number of representations of rationals as a sum of unit fractions. Illinois Journal of Mathematics. 2011;55(2):685-696.","chicago":"Browning, Timothy D, and Christian Elsholtz. “The Number of Representations of Rationals as a Sum of Unit Fractions.” Illinois Journal of Mathematics. University of Illinois Press, 2011.","short":"T.D. Browning, C. Elsholtz, Illinois Journal of Mathematics 55 (2011) 685–696.","mla":"Browning, Timothy D., and Christian Elsholtz. “The Number of Representations of Rationals as a Sum of Unit Fractions.” Illinois Journal of Mathematics, vol. 55, no. 2, University of Illinois Press, 2011, pp. 685–96."},"quality_controlled":"1","article_type":"original","page":"685 - 696","month":"07","day":"01","article_processing_charge":"No","author":[{"id":"35827D50-F248-11E8-B48F-1D18A9856A87","orcid":"0000-0002-8314-0177","first_name":"Timothy D","last_name":"Browning","full_name":"Browning, Timothy D"},{"full_name":"Elsholtz, Christian","first_name":"Christian","last_name":"Elsholtz"}],"date_created":"2018-12-11T11:45:21Z","date_updated":"2021-01-12T06:56:57Z","volume":55,"oa_version":"None","year":"2011","_id":"235","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","publication_status":"published","status":"public","title":"The number of representations of rationals as a sum of unit fractions","publisher":"University of Illinois Press","intvolume":" 55","abstract":[{"text":"For given positive integers m and n, we consider the frequency of representations of m/n as a sum of unit fractions.","lang":"eng"}],"publist_id":"7669","issue":"2","extern":"1","type":"journal_article"},{"abstract":[{"lang":"eng","text":"An asymptotic formula is established for the number of Q-rational points of bounded height on a nonsingular quartic Del Pezzo surface with a conic bundle structure."}],"publist_id":"7668","issue":"1","extern":1,"type":"journal_article","author":[{"full_name":"de la Bretèche, Régis","last_name":"De La Bretèche","first_name":"Régis"},{"full_name":"Timothy Browning","orcid":"0000-0002-8314-0177","id":"35827D50-F248-11E8-B48F-1D18A9856A87","last_name":"Browning","first_name":"Timothy D"}],"date_updated":"2021-01-12T06:57:00Z","date_created":"2018-12-11T11:45:21Z","volume":160,"year":"2011","_id":"236","acknowledgement":"EP/E053262/1\tEngineering and Physical Sciences Research Council","status":"public","publication_status":"published","title":"Manin's conjecture for quartic Del Pezzo surfaces with a conic fibration","intvolume":" 160","publisher":"Duke University Press","month":"09","day":"27","doi":"10.1215/00127094-1443466","date_published":"2011-09-27T00:00:00Z","publication":"Duke Mathematical Journal","citation":{"chicago":"De La Bretèche, Régis, and Timothy D Browning. “Manin’s Conjecture for Quartic Del Pezzo Surfaces with a Conic Fibration.” Duke Mathematical Journal. Duke University Press, 2011. https://doi.org/10.1215/00127094-1443466.","short":"R. De La Bretèche, T.D. Browning, Duke Mathematical Journal 160 (2011) 1–69.","mla":"De La Bretèche, Régis, and Timothy D. Browning. “Manin’s Conjecture for Quartic Del Pezzo Surfaces with a Conic Fibration.” Duke Mathematical Journal, vol. 160, no. 1, Duke University Press, 2011, pp. 1–69, doi:10.1215/00127094-1443466.","apa":"De La Bretèche, R., & Browning, T. D. (2011). Manin’s conjecture for quartic Del Pezzo surfaces with a conic fibration. Duke Mathematical Journal. Duke University Press. https://doi.org/10.1215/00127094-1443466","ieee":"R. De La Bretèche and T. D. Browning, “Manin’s conjecture for quartic Del Pezzo surfaces with a conic fibration,” Duke Mathematical Journal, vol. 160, no. 1. Duke University Press, pp. 1–69, 2011.","ista":"De La Bretèche R, Browning TD. 2011. Manin’s conjecture for quartic Del Pezzo surfaces with a conic fibration. Duke Mathematical Journal. 160(1), 1–69.","ama":"De La Bretèche R, Browning TD. Manin’s conjecture for quartic Del Pezzo surfaces with a conic fibration. Duke Mathematical Journal. 2011;160(1):1-69. doi:10.1215/00127094-1443466"},"quality_controlled":0,"page":"1 - 69"},{"page":"39 - 67","quality_controlled":0,"oa":1,"main_file_link":[{"url":"http://arxiv.org/abs/1004.4892","open_access":"1"}],"citation":{"ama":"Frank R, Lieb É, Seiringer R, Thomas L. Stability and absence of binding for multi-polaron systems. Publications Mathematiques de l Institut des Hautes Etudes Scientifiques. 2011;113(1):39-67. doi:10.1007/s10240-011-0031-5","ieee":"R. Frank, É. Lieb, R. Seiringer, and L. Thomas, “Stability and absence of binding for multi-polaron systems,” Publications Mathematiques de l Institut des Hautes Etudes Scientifiques, vol. 113, no. 1. Springer, pp. 39–67, 2011.","apa":"Frank, R., Lieb, É., Seiringer, R., & Thomas, L. (2011). Stability and absence of binding for multi-polaron systems. Publications Mathematiques de l Institut Des Hautes Etudes Scientifiques. Springer. https://doi.org/10.1007/s10240-011-0031-5","ista":"Frank R, Lieb É, Seiringer R, Thomas L. 2011. Stability and absence of binding for multi-polaron systems. Publications Mathematiques de l Institut des Hautes Etudes Scientifiques. 113(1), 39–67.","short":"R. Frank, É. Lieb, R. Seiringer, L. Thomas, Publications Mathematiques de l Institut Des Hautes Etudes Scientifiques 113 (2011) 39–67.","mla":"Frank, Rupert, et al. “Stability and Absence of Binding for Multi-Polaron Systems.” Publications Mathematiques de l Institut Des Hautes Etudes Scientifiques, vol. 113, no. 1, Springer, 2011, pp. 39–67, doi:10.1007/s10240-011-0031-5.","chicago":"Frank, Rupert, Élliott Lieb, Robert Seiringer, and Lawrence Thomas. “Stability and Absence of Binding for Multi-Polaron Systems.” Publications Mathematiques de l Institut Des Hautes Etudes Scientifiques. Springer, 2011. https://doi.org/10.1007/s10240-011-0031-5."},"publication":"Publications Mathematiques de l Institut des Hautes Etudes Scientifiques","date_published":"2011-06-01T00:00:00Z","doi":"10.1007/s10240-011-0031-5","month":"06","day":"01","intvolume":" 113","publisher":"Springer","publication_status":"published","status":"public","title":"Stability and absence of binding for multi-polaron systems","year":"2011","_id":"2390","volume":113,"date_updated":"2021-01-12T06:57:12Z","date_created":"2018-12-11T11:57:23Z","author":[{"last_name":"Frank","first_name":"Rupert","full_name":"Frank, Rupert L"},{"last_name":"Lieb","first_name":"Élliott","full_name":"Lieb, Élliott H"},{"full_name":"Robert Seiringer","last_name":"Seiringer","first_name":"Robert","orcid":"0000-0002-6781-0521","id":"4AFD0470-F248-11E8-B48F-1D18A9856A87"},{"first_name":"Lawrence","last_name":"Thomas","full_name":"Thomas, Lawrence E"}],"type":"journal_article","extern":1,"publist_id":"4534","issue":"1","abstract":[{"text":"We resolve several longstanding problems concerning the stability and the absence of multi-particle binding for N≥2 polarons. Fröhlich's 1937 polaron model describes non-relativistic particles interacting with a scalar quantized field with coupling √α, and with each other by Coulomb repulsion of strength U. We prove the following: (i) While there is a known thermodynamic instability for U<2α, stability of matter does hold for U>2α, that is, the ground state energy per particle has a finite limit as N→∞. (ii) There is no binding of any kind if U exceeds a critical value that depends on α but not on N. The same results are shown to hold for the Pekar-Tomasevich model.","lang":"eng"}]},{"doi":"10.1103/PhysRevLett.106.150402","date_published":"2011-01-01T00:00:00Z","quality_controlled":0,"citation":{"chicago":"Frank, Rupert, Mathieu Lewin, Élliott Lieb, and Robert Seiringer. “Energy Cost to Make a Hole in the Fermi Sea.” Physical Review Letters. American Physical Society, 2011. https://doi.org/10.1103/PhysRevLett.106.150402.","mla":"Frank, Rupert, et al. “Energy Cost to Make a Hole in the Fermi Sea.” Physical Review Letters, vol. 106, no. 15, American Physical Society, 2011, doi:10.1103/PhysRevLett.106.150402.","short":"R. Frank, M. Lewin, É. Lieb, R. Seiringer, Physical Review Letters 106 (2011).","ista":"Frank R, Lewin M, Lieb É, Seiringer R. 2011. Energy cost to make a hole in the fermi sea. Physical Review Letters. 106(15).","apa":"Frank, R., Lewin, M., Lieb, É., & Seiringer, R. (2011). Energy cost to make a hole in the fermi sea. Physical Review Letters. American Physical Society. https://doi.org/10.1103/PhysRevLett.106.150402","ieee":"R. Frank, M. Lewin, É. Lieb, and R. Seiringer, “Energy cost to make a hole in the fermi sea,” Physical Review Letters, vol. 106, no. 15. American Physical Society, 2011.","ama":"Frank R, Lewin M, Lieb É, Seiringer R. Energy cost to make a hole in the fermi sea. Physical Review Letters. 2011;106(15). doi:10.1103/PhysRevLett.106.150402"},"main_file_link":[{"url":"http://arxiv.org/abs/1102.1414","open_access":"1"}],"oa":1,"publication":"Physical Review Letters","day":"01","month":"01","volume":106,"date_updated":"2021-01-12T06:57:12Z","date_created":"2018-12-11T11:57:24Z","author":[{"full_name":"Frank, Rupert L","first_name":"Rupert","last_name":"Frank"},{"last_name":"Lewin","first_name":"Mathieu","full_name":"Lewin, Mathieu"},{"first_name":"Élliott","last_name":"Lieb","full_name":"Lieb, Élliott H"},{"orcid":"0000-0002-6781-0521","id":"4AFD0470-F248-11E8-B48F-1D18A9856A87","last_name":"Seiringer","first_name":"Robert","full_name":"Robert Seiringer"}],"publisher":"American Physical Society","intvolume":" 106","title":"Energy cost to make a hole in the fermi sea","status":"public","publication_status":"published","_id":"2391","year":"2011","extern":1,"issue":"15","publist_id":"4535","abstract":[{"lang":"eng","text":"The change in energy of an ideal Fermi gas when a local one-body potential is inserted into the system, or when the density is changed locally, are important quantities in condensed matter physics. We show that they can be rigorously bounded from below by a universal constant times the value given by the semiclassical approximation."}],"type":"journal_article"},{"status":"public","title":"Least zero of a cubic form","publication_status":"published","publisher":"Springer","intvolume":" 352","_id":"239","year":"2011","acknowledgement":"EP/E053262/1\tEngineering and Physical Sciences Research Council","date_updated":"2021-01-12T06:57:11Z","date_created":"2018-12-11T11:45:22Z","volume":352,"author":[{"first_name":"Timothy D","last_name":"Browning","id":"35827D50-F248-11E8-B48F-1D18A9856A87","orcid":"0000-0002-8314-0177","full_name":"Timothy Browning"},{"first_name":"Rainer","last_name":"Dietmann","full_name":"Dietmann, Rainer"},{"first_name":"Peter","last_name":"Elliott","full_name":"Elliott, Peter"}],"type":"journal_article","extern":1,"abstract":[{"text":"An effective search bound is established for the least non-trivial integer zero of an arbitrary cubic form C ε ℤ[X 1,...,X n], provided that n ≥ 17.","lang":"eng"}],"issue":"3","publist_id":"7665","quality_controlled":0,"page":"745 - 778","publication":"Mathematische Annalen","citation":{"short":"T.D. Browning, R. Dietmann, P. Elliott, Mathematische Annalen 352 (2011) 745–778.","mla":"Browning, Timothy D., et al. “Least Zero of a Cubic Form.” Mathematische Annalen, vol. 352, no. 3, Springer, 2011, pp. 745–78, doi:10.1007/s00208-011-0651-6.","chicago":"Browning, Timothy D, Rainer Dietmann, and Peter Elliott. “Least Zero of a Cubic Form.” Mathematische Annalen. Springer, 2011. https://doi.org/10.1007/s00208-011-0651-6.","ama":"Browning TD, Dietmann R, Elliott P. Least zero of a cubic form. Mathematische Annalen. 2011;352(3):745-778. doi:10.1007/s00208-011-0651-6","apa":"Browning, T. D., Dietmann, R., & Elliott, P. (2011). Least zero of a cubic form. Mathematische Annalen. Springer. https://doi.org/10.1007/s00208-011-0651-6","ieee":"T. D. Browning, R. Dietmann, and P. Elliott, “Least zero of a cubic form,” Mathematische Annalen, vol. 352, no. 3. Springer, pp. 745–778, 2011.","ista":"Browning TD, Dietmann R, Elliott P. 2011. Least zero of a cubic form. Mathematische Annalen. 352(3), 745–778."},"doi":"10.1007/s00208-011-0651-6","date_published":"2011-03-06T00:00:00Z","month":"03","day":"06"},{"publist_id":"4533","issue":"2","abstract":[{"text":"We investigate the low energy excitation spectrum of a Bose gas with weak, long range repulsive interactions. In particular, we prove that the Bogoliubov spectrum of elementary excitations with linear dispersion relation for small momentum becomes exact in the mean-field limit.","lang":"eng"}],"extern":1,"type":"journal_article","author":[{"full_name":"Robert Seiringer","id":"4AFD0470-F248-11E8-B48F-1D18A9856A87","orcid":"0000-0002-6781-0521","first_name":"Robert","last_name":"Seiringer"}],"volume":306,"date_created":"2018-12-11T11:57:24Z","date_updated":"2021-01-12T06:57:13Z","_id":"2393","year":"2011","publisher":"Springer","intvolume":" 306","title":"The excitation spectrum for weakly interacting Bosons","status":"public","publication_status":"published","day":"01","month":"09","doi":"10.1007/s00220-011-1261-6","date_published":"2011-09-01T00:00:00Z","oa":1,"main_file_link":[{"open_access":"1","url":"http://arxiv.org/abs/1008.5349"}],"citation":{"ama":"Seiringer R. The excitation spectrum for weakly interacting Bosons. Communications in Mathematical Physics. 2011;306(2):565-578. doi:10.1007/s00220-011-1261-6","ieee":"R. Seiringer, “The excitation spectrum for weakly interacting Bosons,” Communications in Mathematical Physics, vol. 306, no. 2. Springer, pp. 565–578, 2011.","apa":"Seiringer, R. (2011). The excitation spectrum for weakly interacting Bosons. Communications in Mathematical Physics. Springer. https://doi.org/10.1007/s00220-011-1261-6","ista":"Seiringer R. 2011. The excitation spectrum for weakly interacting Bosons. Communications in Mathematical Physics. 306(2), 565–578.","short":"R. Seiringer, Communications in Mathematical Physics 306 (2011) 565–578.","mla":"Seiringer, Robert. “The Excitation Spectrum for Weakly Interacting Bosons.” Communications in Mathematical Physics, vol. 306, no. 2, Springer, 2011, pp. 565–78, doi:10.1007/s00220-011-1261-6.","chicago":"Seiringer, Robert. “The Excitation Spectrum for Weakly Interacting Bosons.” Communications in Mathematical Physics. Springer, 2011. https://doi.org/10.1007/s00220-011-1261-6."},"publication":"Communications in Mathematical Physics","page":"565 - 578","quality_controlled":0},{"abstract":[{"lang":"eng","text":"Let EMBEDk→d be the following algorithmic problem: Given a finite simplicial complex K of dimension at most k, does there exist a (piecewise linear) embedding of K into Rd? Known results easily imply the polynomiality of EMBEDk→2 (k = 1; 2; the case k = 1, d = 2 is graph planarity) and of EMBEDk→2k for all k ≥ 3. We show that the celebrated result of Novikov on the algorithmic unsolvability of recognizing the 5-sphere implies that EMBEDd→d and EMBED (d-1)→d are undecidable for each d ≥ 5. Our main result is the NP-hardness of EMBED2→4 and, more generally, of EMBED k→d for all k; d with d ≥ 4 and d ≥ k ≥ (2d - 2)/3. These dimensions fall outside the metastable range of a theorem of Haefliger and Weber, which characterizes embeddability using the deleted product obstruction. Our reductions are based on examples, due to Segal, Spież, Freedman, Krushkal, Teichner, and Skopenkov, showing that outside the metastable range the deleted product obstruction is not sufficient to characterize embeddability. "}],"issue":"2","publist_id":"4470","extern":1,"type":"journal_article","author":[{"last_name":"Matoušek","first_name":"Jiří","full_name":"Matoušek, Jiří"},{"full_name":"Martin Tancer","orcid":"0000-0002-1191-6714","id":"38AC689C-F248-11E8-B48F-1D18A9856A87","last_name":"Tancer","first_name":"Martin"},{"full_name":"Uli Wagner","id":"36690CA2-F248-11E8-B48F-1D18A9856A87","orcid":"0000-0002-1494-0568","first_name":"Uli","last_name":"Wagner"}],"date_created":"2018-12-11T11:57:39Z","date_updated":"2021-01-12T06:57:28Z","volume":13,"acknowledgement":"We would like to thank Colin Rourke for explanations concerning PL topology and for examples showing the difference between PL embeddability and topological embeddability\nmentioned in Section 2. We also thank Michael Joswig, Gil Kalai, Frank Lutz, Alexander Nabutovsky, and Robin Thomas for kindly answering our questions. The second author would also like to thank Sergio Cabello for helpful discussions regarding linear-time algorithms for EMBED2!2.\nFinally, we are grateful to two anonymous referees for careful reading and valuable suggestions.\nResearch of U.Wagner was supported by the Swiss National Science Foundation (SNF Projects\n200021-116741 and 200021-125309).","_id":"2436","year":"2011","status":"public","publication_status":"published","title":"Hardness of embedding simplicial complexes in Rd","publisher":"European Mathematical Society","intvolume":" 13","day":"01","month":"01","date_published":"2011-01-01T00:00:00Z","doi":"10.4171/JEMS/252","publication":"Journal of the European Mathematical Society","citation":{"mla":"Matoušek, Jiří, et al. “Hardness of Embedding Simplicial Complexes in Rd.” Journal of the European Mathematical Society, vol. 13, no. 2, European Mathematical Society, 2011, pp. 259–95, doi:10.4171/JEMS/252.","short":"J. Matoušek, M. Tancer, U. Wagner, Journal of the European Mathematical Society 13 (2011) 259–295.","chicago":"Matoušek, Jiří, Martin Tancer, and Uli Wagner. “Hardness of Embedding Simplicial Complexes in Rd.” Journal of the European Mathematical Society. European Mathematical Society, 2011. https://doi.org/10.4171/JEMS/252.","ama":"Matoušek J, Tancer M, Wagner U. Hardness of embedding simplicial complexes in Rd. Journal of the European Mathematical Society. 2011;13(2):259-295. doi:10.4171/JEMS/252","ista":"Matoušek J, Tancer M, Wagner U. 2011. Hardness of embedding simplicial complexes in Rd. Journal of the European Mathematical Society. 13(2), 259–295.","ieee":"J. Matoušek, M. Tancer, and U. Wagner, “Hardness of embedding simplicial complexes in Rd,” Journal of the European Mathematical Society, vol. 13, no. 2. European Mathematical Society, pp. 259–295, 2011.","apa":"Matoušek, J., Tancer, M., & Wagner, U. (2011). Hardness of embedding simplicial complexes in Rd. Journal of the European Mathematical Society. European Mathematical Society. https://doi.org/10.4171/JEMS/252"},"quality_controlled":0,"page":"259 - 295"},{"_id":"2437","year":"2011","publisher":"ACM","publication_status":"published","title":"Minors in random and expanding hypergraphs","status":"public","author":[{"full_name":"Uli Wagner","last_name":"Wagner","first_name":"Uli","orcid":"0000-0002-1494-0568","id":"36690CA2-F248-11E8-B48F-1D18A9856A87"}],"date_updated":"2021-01-12T06:57:29Z","date_created":"2018-12-11T11:57:39Z","type":"conference","publist_id":"4469","abstract":[{"lang":"eng","text":"We introduce a new notion of minors for simplicial complexes (hypergraphs), so-called homological minors. Our motivation is to propose a general approach to attack certain extremal problems for sparse simplicial complexes and the corresponding threshold problems for random complexes. In this paper, we focus on threshold problems. The basic model for random complexes is the Linial-Meshulam model Xk(n, p). By definition, such a complex has n vertices, a complete (k -1)-dimensional skeleton, and every possible k-dimensional simplex is chosen independently with probability p. We show that for every k, t≥ 1, there is a constant C = C(k, t) such that for p≥ C/n, the random complex Xk(n, p) asymptotically almost surely contains K tk (the complete k-dimensional complex on t vertices) as a homological minor. As corollary, the threshold for (topological) embeddability of Xk(n, p) into R2k is at p = θ(1/n). The method can be extended to other models of random complexes (for which the lower skeleta are not necessarily complete) and also to more general Tverberg-type problems, where instead of continuous maps without doubly covered image points (embeddings), we consider maps without qfold covered image points."}],"extern":1,"citation":{"mla":"Wagner, Uli. Minors in Random and Expanding Hypergraphs. ACM, 2011, pp. 351–60, doi:10.1145/1998196.1998256.","short":"U. Wagner, in:, ACM, 2011, pp. 351–360.","chicago":"Wagner, Uli. “Minors in Random and Expanding Hypergraphs,” 351–60. ACM, 2011. https://doi.org/10.1145/1998196.1998256.","ama":"Wagner U. Minors in random and expanding hypergraphs. In: ACM; 2011:351-360. doi:10.1145/1998196.1998256","ista":"Wagner U. 2011. Minors in random and expanding hypergraphs. SGC: Symposuim on Computational Geometry, 351–360.","apa":"Wagner, U. (2011). Minors in random and expanding hypergraphs (pp. 351–360). Presented at the SGC: Symposuim on Computational Geometry, ACM. https://doi.org/10.1145/1998196.1998256","ieee":"U. Wagner, “Minors in random and expanding hypergraphs,” presented at the SGC: Symposuim on Computational Geometry, 2011, pp. 351–360."},"page":"351 - 360","quality_controlled":0,"date_published":"2011-01-01T00:00:00Z","doi":"10.1145/1998196.1998256","conference":{"name":"SGC: Symposuim on Computational Geometry"},"month":"01","day":"01"},{"author":[{"full_name":"Hongjiang Li","first_name":"Hongjiang","last_name":"Li","id":"33CA54A6-F248-11E8-B48F-1D18A9856A87","orcid":"0000-0001-5039-9660"},{"last_name":"Lin","first_name":"Deshu","full_name":"Lin, Deshu"},{"full_name":"Dhonukshe, Pankaj B","last_name":"Dhonukshe","first_name":"Pankaj"},{"last_name":"Nagawa","first_name":"Shingo","full_name":"Nagawa, Shingo"},{"full_name":"Chen, Dandan","last_name":"Chen","first_name":"Dandan"},{"last_name":"Friml","first_name":"Jirí","orcid":"0000-0002-8302-7596","id":"4159519E-F248-11E8-B48F-1D18A9856A87","full_name":"Jirí Friml"},{"full_name":"Scheres, Ben","last_name":"Scheres","first_name":"Ben"},{"full_name":"Guo, Hongwei","first_name":"Hongwei","last_name":"Guo"},{"last_name":"Yang","first_name":"Zhenbiao","full_name":"Yang, Zhenbiao"}],"volume":21,"date_created":"2018-12-11T11:57:45Z","date_updated":"2021-01-12T06:57:35Z","_id":"2454","year":"2011","intvolume":" 21","publisher":"Nature Publishing Group","publication_status":"published","title":"Phosphorylation switch modulates the interdigitated pattern of PIN1 localization and cell expansion in Arabidopsis leaf epidermis","status":"public","issue":"6","publist_id":"4449","abstract":[{"lang":"eng","text":"Within a multicellular tissue cells may coordinately form a singular or multiple polar axes, but it is unclear whether a common mechanism governs different types of polar axis formation. The phosphorylation status of PIN proteins, which is directly affected by the PINOID (PID) protein kinase and the PP2A protein phosphatase, is known to regulate the apical-basal polarity of PIN localization in bipolar cells of roots and shoot apices. Here, we provide evidence that the phosphorylation status-mediated PIN polarity switch is widely used to modulate cellular processes in Arabidopsis including multipolar pavement cells (PC) with interdigitated lobes and indentations. The degree of PC interdigitation was greatly reduced either when the FYPP1 gene, which encodes a PP2A called phytochrome-associated serine/threonine protein phosphatase, was knocked out or when the PID gene was overexpressed (35S:PID). These genetic modifications caused PIN1 localization to switch from lobe to indentation regions. The PP2A and PID mediated switching of PIN1 localization is strikingly similar to their regulation of the apical-basal polarity switch of PIN proteins in other cells. Our findings suggest a common mechanism for the regulation of PIN1 polarity formation, a fundamental cellular process that is crucial for pattern formation both at the tissue/organ and cellular levels."}],"extern":1,"type":"journal_article","doi":"10.1038/cr.2011.49","date_published":"2011-06-01T00:00:00Z","citation":{"ieee":"H. Li et al., “Phosphorylation switch modulates the interdigitated pattern of PIN1 localization and cell expansion in Arabidopsis leaf epidermis,” Cell Research, vol. 21, no. 6. Nature Publishing Group, pp. 970–978, 2011.","apa":"Li, H., Lin, D., Dhonukshe, P., Nagawa, S., Chen, D., Friml, J., … Yang, Z. (2011). Phosphorylation switch modulates the interdigitated pattern of PIN1 localization and cell expansion in Arabidopsis leaf epidermis. Cell Research. Nature Publishing Group. https://doi.org/10.1038/cr.2011.49","ista":"Li H, Lin D, Dhonukshe P, Nagawa S, Chen D, Friml J, Scheres B, Guo H, Yang Z. 2011. Phosphorylation switch modulates the interdigitated pattern of PIN1 localization and cell expansion in Arabidopsis leaf epidermis. Cell Research. 21(6), 970–978.","ama":"Li H, Lin D, Dhonukshe P, et al. Phosphorylation switch modulates the interdigitated pattern of PIN1 localization and cell expansion in Arabidopsis leaf epidermis. Cell Research. 2011;21(6):970-978. doi:10.1038/cr.2011.49","chicago":"Li, Hongjiang, Deshu Lin, Pankaj Dhonukshe, Shingo Nagawa, Dandan Chen, Jiří Friml, Ben Scheres, Hongwei Guo, and Zhenbiao Yang. “Phosphorylation Switch Modulates the Interdigitated Pattern of PIN1 Localization and Cell Expansion in Arabidopsis Leaf Epidermis.” Cell Research. Nature Publishing Group, 2011. https://doi.org/10.1038/cr.2011.49.","short":"H. Li, D. Lin, P. Dhonukshe, S. Nagawa, D. Chen, J. Friml, B. Scheres, H. Guo, Z. Yang, Cell Research 21 (2011) 970–978.","mla":"Li, Hongjiang, et al. “Phosphorylation Switch Modulates the Interdigitated Pattern of PIN1 Localization and Cell Expansion in Arabidopsis Leaf Epidermis.” Cell Research, vol. 21, no. 6, Nature Publishing Group, 2011, pp. 970–78, doi:10.1038/cr.2011.49."},"oa":1,"main_file_link":[{"open_access":"1","url":"http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3203702/"}],"publication":"Cell Research","page":"970 - 978","quality_controlled":0,"month":"06","day":"01"},{"abstract":[{"lang":"eng","text":"In unicellular and multicellular organisms, cell polarity is essential for a wide range of biological processes. An important feature of cell polarity is the asymmetric distribution of proteins in or at the plasma membrane. In plants such polar localized proteins play various specific roles ranging from organizing cell morphogenesis, asymmetric cell division, pathogen defense, nutrient transport and establishment of hormone gradients for developmental patterning. Moreover, flexible respecification of cell polarities enables plants to adjust their physiology and development to environmental changes. Having evolved multicellularity independently and lacking major cell polarity mechanisms of animal cells, plants came up with alternative solutions to generate and respecify cell polarity as well as to regulate polar domains at the plasma membrane."}],"publist_id":"4443","issue":"6","extern":"1","type":"journal_article","author":[{"full_name":"Dettmer, Jan","last_name":"Dettmer","first_name":"Jan"},{"orcid":"0000-0002-8302-7596","id":"4159519E-F248-11E8-B48F-1D18A9856A87","last_name":"Friml","first_name":"Jirí","full_name":"Friml, Jirí"}],"date_updated":"2021-01-12T06:57:37Z","date_created":"2018-12-11T11:57:47Z","oa_version":"None","volume":23,"user_id":"3E5EF7F0-F248-11E8-B48F-1D18A9856A87","_id":"2460","year":"2011","title":"Cell polarity in plants: When two do the same, it is not the same...","status":"public","publication_status":"published","intvolume":" 23","publisher":"Elsevier","day":"01","month":"12","doi":"10.1016/j.ceb.2011.09.006","date_published":"2011-12-01T00:00:00Z","language":[{"iso":"eng"}],"publication":"Current Opinion in Cell Biology","citation":{"apa":"Dettmer, J., & Friml, J. (2011). Cell polarity in plants: When two do the same, it is not the same... Current Opinion in Cell Biology. Elsevier. https://doi.org/10.1016/j.ceb.2011.09.006","ieee":"J. Dettmer and J. Friml, “Cell polarity in plants: When two do the same, it is not the same...,” Current Opinion in Cell Biology, vol. 23, no. 6. Elsevier, pp. 686–696, 2011.","ista":"Dettmer J, Friml J. 2011. Cell polarity in plants: When two do the same, it is not the same... Current Opinion in Cell Biology. 23(6), 686–696.","ama":"Dettmer J, Friml J. Cell polarity in plants: When two do the same, it is not the same... Current Opinion in Cell Biology. 2011;23(6):686-696. doi:10.1016/j.ceb.2011.09.006","chicago":"Dettmer, Jan, and Jiří Friml. “Cell Polarity in Plants: When Two Do the Same, It Is Not the Same...” Current Opinion in Cell Biology. Elsevier, 2011. https://doi.org/10.1016/j.ceb.2011.09.006.","short":"J. Dettmer, J. Friml, Current Opinion in Cell Biology 23 (2011) 686–696.","mla":"Dettmer, Jan, and Jiří Friml. “Cell Polarity in Plants: When Two Do the Same, It Is Not the Same...” Current Opinion in Cell Biology, vol. 23, no. 6, Elsevier, 2011, pp. 686–96, doi:10.1016/j.ceb.2011.09.006."},"quality_controlled":"1","page":"686 - 696"},{"month":"01","day":"01","date_published":"2011-01-01T00:00:00Z","doi":"10.1038/nn.2692","page":"85 - 94","quality_controlled":0,"citation":{"chicago":"Chan, Savio, Kelly Glajch, Tracy Gertler, Jaime Guzmán, Jeff Mercer, Alan Lewis, Alan Goldberg, et al. “HCN Channelopathy in External Globus Pallidus Neurons in Models of Parkinson s Disease.” Nature Neuroscience. Nature Publishing Group, 2011. https://doi.org/10.1038/nn.2692.","short":"S. Chan, K. Glajch, T. Gertler, J. Guzmán, J. Mercer, A. Lewis, A. Goldberg, T. Tkatch, R. Shigemoto, S. Fleming, D. Chetkovich, P. Osten, H. Kita, J. Surmeier, Nature Neuroscience 14 (2011) 85–94.","mla":"Chan, Savio, et al. “HCN Channelopathy in External Globus Pallidus Neurons in Models of Parkinson s Disease.” Nature Neuroscience, vol. 14, no. 1, Nature Publishing Group, 2011, pp. 85–94, doi:10.1038/nn.2692.","apa":"Chan, S., Glajch, K., Gertler, T., Guzmán, J., Mercer, J., Lewis, A., … Surmeier, J. (2011). HCN channelopathy in external globus pallidus neurons in models of Parkinson s disease. Nature Neuroscience. Nature Publishing Group. https://doi.org/10.1038/nn.2692","ieee":"S. Chan et al., “HCN channelopathy in external globus pallidus neurons in models of Parkinson s disease,” Nature Neuroscience, vol. 14, no. 1. Nature Publishing Group, pp. 85–94, 2011.","ista":"Chan S, Glajch K, Gertler T, Guzmán J, Mercer J, Lewis A, Goldberg A, Tkatch T, Shigemoto R, Fleming S, Chetkovich D, Osten P, Kita H, Surmeier J. 2011. HCN channelopathy in external globus pallidus neurons in models of Parkinson s disease. Nature Neuroscience. 14(1), 85–94.","ama":"Chan S, Glajch K, Gertler T, et al. HCN channelopathy in external globus pallidus neurons in models of Parkinson s disease. Nature Neuroscience. 2011;14(1):85-94. doi:10.1038/nn.2692"},"publication":"Nature Neuroscience","extern":1,"issue":"1","publist_id":"4390","abstract":[{"text":"Parkinson's disease is a common neurodegenerative disorder characterized by a profound motor disability that is traceable to the emergence of synchronous, rhythmic spiking in neurons of the external segment of the globus pallidus (GPe). The origins of this pathophysiology are poorly defined for the generation of pacemaking. After the induction of a parkinsonian state in mice, there was a progressive decline in autonomous GPe pacemaking, which normally serves to desynchronize activity. The loss was attributable to the downregulation of an ion channel that is essential in pacemaking, the hyperpolarization and cyclic nucleotide-gated (HCN) channel. Viral delivery of HCN2 subunits restored pacemaking and reduced burst spiking in GPe neurons. However, the motor disability induced by dopamine (DA) depletion was not reversed, suggesting that the loss of pacemaking was a consequence, rather than a cause, of key network pathophysiology, a conclusion that is consistent with the ability of L-type channel antagonists to attenuate silencing after DA depletion.","lang":"eng"}],"type":"journal_article","volume":14,"date_updated":"2021-01-12T06:57:56Z","date_created":"2018-12-11T11:58:06Z","author":[{"full_name":"Chan, Savio","first_name":"Savio","last_name":"Chan"},{"first_name":"Kelly","last_name":"Glajch","full_name":"Glajch, Kelly E"},{"full_name":"Gertler, Tracy S","last_name":"Gertler","first_name":"Tracy"},{"full_name":"Guzmán, Jaime N","first_name":"Jaime","last_name":"Guzmán"},{"full_name":"Mercer, Jeff N","first_name":"Jeff","last_name":"Mercer"},{"full_name":"Lewis, Alan S","first_name":"Alan","last_name":"Lewis"},{"full_name":"Goldberg, Alan B","first_name":"Alan","last_name":"Goldberg"},{"full_name":"Tkatch, Tatiana","last_name":"Tkatch","first_name":"Tatiana"},{"full_name":"Ryuichi Shigemoto","orcid":"0000-0001-8761-9444","id":"499F3ABC-F248-11E8-B48F-1D18A9856A87","last_name":"Shigemoto","first_name":"Ryuichi"},{"full_name":"Fleming, Sheila M","first_name":"Sheila","last_name":"Fleming"},{"last_name":"Chetkovich","first_name":"Dane","full_name":"Chetkovich, Dane M"},{"first_name":"Pavel","last_name":"Osten","full_name":"Osten, Pavel"},{"last_name":"Kita","first_name":"Hitoshi","full_name":"Kita, Hitoshi"},{"first_name":"James","last_name":"Surmeier","full_name":"Surmeier, James D"}],"publisher":"Nature Publishing Group","intvolume":" 14","status":"public","title":"HCN channelopathy in external globus pallidus neurons in models of Parkinson s disease","publication_status":"published","year":"2011","_id":"2511"},{"abstract":[{"lang":"eng","text":"GABAergic inhibition plays a central role in the control of pyramidal cell ensemble activities; thus, any signaling mechanism that regulates inhibition is able to fine-tune network patterns. Here, we provide evidence that the retrograde nitric oxide (NO)- cGMP cascade triggered by NMDA receptor (NMDAR) activation plays a role in the control of hippocampal GABAergic transmission in mice. GABAergic synapses express neuronal nitric oxide synthase (nNOS) postsynaptically and NO receptors (NO-sensitive guanylyl cyclase) in the presynaptic terminals. We hypothesized that-similar to glutamatergic synapses-the Ca 2+ transients required to activate nNOS were provided by NMDA receptor activation. Indeed, administration of 5 μm NMDA induced a robust nNOS-dependent cGMP production in GABAergic terminals, selectively in the CA1 and CA3c areas. Furthermore, using preembedding, postembedding, and SDS-digested freeze-fracture replica immunogold labeling, we provided quantitative immunocytochemical evidence that NMDAR subunits GluN1, GluN2A, and GluN2B were present in most somatic GABAergic synapses postsynaptically. These data indicate that NMDARs can modulate hippocampal GABAergic inhibition via NO- cGMP signaling in an activity-dependent manner and that this effect is subregion specific in the mouse hippocampus."}],"issue":"16","publist_id":"4389","extern":1,"type":"journal_article","author":[{"full_name":"Szabadits, Eszter","first_name":"Eszter","last_name":"Szabadits"},{"first_name":"Csaba","last_name":"Cserép","full_name":"Cserép, Csaba"},{"last_name":"Szonyi","first_name":"András","full_name":"Szonyi, András"},{"full_name":"Fukazawa, Yugo","first_name":"Yugo","last_name":"Fukazawa"},{"first_name":"Ryuichi","last_name":"Shigemoto","id":"499F3ABC-F248-11E8-B48F-1D18A9856A87","orcid":"0000-0001-8761-9444","full_name":"Ryuichi Shigemoto"},{"first_name":"Masahiko","last_name":"Watanabe","full_name":"Watanabe, Masahiko"},{"full_name":"Itohara, Shigeyoshi","first_name":"Shigeyoshi","last_name":"Itohara"},{"first_name":"Tamás","last_name":"Freund","full_name":"Freund, Tamás F"},{"last_name":"Nyíri","first_name":"Gábor","full_name":"Nyíri, Gábor"}],"date_updated":"2021-01-12T06:57:56Z","date_created":"2018-12-11T11:58:06Z","volume":31,"year":"2011","_id":"2512","status":"public","title":"NMDA receptors in hippocampal GABAergic synapses and their role in nitric oxide signaling","publication_status":"published","publisher":"Society for Neuroscience","intvolume":" 31","day":"20","month":"04","doi":"10.1523/JNEUROSCI.5938-10.2011","date_published":"2011-04-20T00:00:00Z","publication":"Journal of Neuroscience","citation":{"ama":"Szabadits E, Cserép C, Szonyi A, et al. NMDA receptors in hippocampal GABAergic synapses and their role in nitric oxide signaling. Journal of Neuroscience. 2011;31(16):5893-5904. doi:10.1523/JNEUROSCI.5938-10.2011","apa":"Szabadits, E., Cserép, C., Szonyi, A., Fukazawa, Y., Shigemoto, R., Watanabe, M., … Nyíri, G. (2011). NMDA receptors in hippocampal GABAergic synapses and their role in nitric oxide signaling. Journal of Neuroscience. Society for Neuroscience. https://doi.org/10.1523/JNEUROSCI.5938-10.2011","ieee":"E. Szabadits et al., “NMDA receptors in hippocampal GABAergic synapses and their role in nitric oxide signaling,” Journal of Neuroscience, vol. 31, no. 16. Society for Neuroscience, pp. 5893–5904, 2011.","ista":"Szabadits E, Cserép C, Szonyi A, Fukazawa Y, Shigemoto R, Watanabe M, Itohara S, Freund T, Nyíri G. 2011. NMDA receptors in hippocampal GABAergic synapses and their role in nitric oxide signaling. Journal of Neuroscience. 31(16), 5893–5904.","short":"E. Szabadits, C. Cserép, A. Szonyi, Y. Fukazawa, R. Shigemoto, M. Watanabe, S. Itohara, T. Freund, G. Nyíri, Journal of Neuroscience 31 (2011) 5893–5904.","mla":"Szabadits, Eszter, et al. “NMDA Receptors in Hippocampal GABAergic Synapses and Their Role in Nitric Oxide Signaling.” Journal of Neuroscience, vol. 31, no. 16, Society for Neuroscience, 2011, pp. 5893–904, doi:10.1523/JNEUROSCI.5938-10.2011.","chicago":"Szabadits, Eszter, Csaba Cserép, András Szonyi, Yugo Fukazawa, Ryuichi Shigemoto, Masahiko Watanabe, Shigeyoshi Itohara, Tamás Freund, and Gábor Nyíri. “NMDA Receptors in Hippocampal GABAergic Synapses and Their Role in Nitric Oxide Signaling.” Journal of Neuroscience. Society for Neuroscience, 2011. https://doi.org/10.1523/JNEUROSCI.5938-10.2011."},"quality_controlled":0,"page":"5893 - 5904"},{"day":"01","month":"06","publication":"Nature Neuroscience","citation":{"apa":"Allen, D., Bond, C., Luján, R., Ballesteros Merino, C., Lin, M., Wang, K., … Adelman, J. (2011). The SK2-long isoform directs synaptic localization and function of SK2-containing channels. Nature Neuroscience. Nature Publishing Group. https://doi.org/10.1038/nn.2832","ieee":"D. Allen et al., “The SK2-long isoform directs synaptic localization and function of SK2-containing channels,” Nature Neuroscience, vol. 14, no. 6. Nature Publishing Group, pp. 744–749, 2011.","ista":"Allen D, Bond C, Luján R, Ballesteros Merino C, Lin M, Wang K, Klett N, Watanabe M, Shigemoto R, Stackman R, Maylie J, Adelman J. 2011. The SK2-long isoform directs synaptic localization and function of SK2-containing channels. Nature Neuroscience. 14(6), 744–749.","ama":"Allen D, Bond C, Luján R, et al. The SK2-long isoform directs synaptic localization and function of SK2-containing channels. Nature Neuroscience. 2011;14(6):744-749. doi:10.1038/nn.2832","chicago":"Allen, Duane, Chris Bond, Rafael Luján, Carmen Ballesteros Merino, Michael Lin, Kang Wang, Nathan Klett, et al. “The SK2-Long Isoform Directs Synaptic Localization and Function of SK2-Containing Channels.” Nature Neuroscience. Nature Publishing Group, 2011. https://doi.org/10.1038/nn.2832.","short":"D. Allen, C. Bond, R. Luján, C. Ballesteros Merino, M. Lin, K. Wang, N. Klett, M. Watanabe, R. Shigemoto, R. Stackman, J. Maylie, J. Adelman, Nature Neuroscience 14 (2011) 744–749.","mla":"Allen, Duane, et al. “The SK2-Long Isoform Directs Synaptic Localization and Function of SK2-Containing Channels.” Nature Neuroscience, vol. 14, no. 6, Nature Publishing Group, 2011, pp. 744–49, doi:10.1038/nn.2832."},"quality_controlled":0,"page":"744 - 749","date_published":"2011-06-01T00:00:00Z","doi":"10.1038/nn.2832","type":"journal_article","abstract":[{"lang":"eng","text":"SK2-containing channels are expressed in the postsynaptic density (PSD) of dendritic spines on mouse hippocampal area CA1 pyramidal neurons and influence synaptic responses, plasticity and learning. The Sk2 gene (also known as Kcnn2) encodes two isoforms that differ only in the length of their N-terminal domains. SK2-long (SK2-L) and SK2-short (SK2-S) are coexpressed in CA1 pyramidal neurons and likely form heteromeric channels. In mice lacking SK2-L (SK2-S only mice), SK2-S-containing channels were expressed in the extrasynaptic membrane, but were excluded from the PSD. The SK channel contribution to excitatory postsynaptic potentials was absent in SK2-S only mice and was restored by SK2-L re-expression. Blocking SK channels increased the amount of long-term potentiation induced in area CA1 in slices from wild-type mice but had no effect in slices from SK2-S only mice. Furthermore, SK2-S only mice outperformed wild-type mice in the novel object recognition task. These results indicate that SK2-L directs synaptic SK2-containing channel expression and is important for normal synaptic signaling, plasticity and learning. "}],"issue":"6","publist_id":"4388","extern":1,"year":"2011","_id":"2513","publication_status":"published","title":"The SK2-long isoform directs synaptic localization and function of SK2-containing channels","status":"public","publisher":"Nature Publishing Group","intvolume":" 14","author":[{"full_name":"Allen, Duane H","last_name":"Allen","first_name":"Duane"},{"full_name":"Bond, Chris T","first_name":"Chris","last_name":"Bond"},{"last_name":"Luján","first_name":"Rafael","full_name":"Luján, Rafael"},{"first_name":"Carmen","last_name":"Ballesteros Merino","full_name":"Ballesteros-Merino, Carmen"},{"full_name":"Lin, Michael T","first_name":"Michael","last_name":"Lin"},{"full_name":"Wang, Kang","last_name":"Wang","first_name":"Kang"},{"last_name":"Klett","first_name":"Nathan","full_name":"Klett, Nathan"},{"full_name":"Watanabe, Masahiko","last_name":"Watanabe","first_name":"Masahiko"},{"full_name":"Ryuichi Shigemoto","orcid":"0000-0001-8761-9444","id":"499F3ABC-F248-11E8-B48F-1D18A9856A87","last_name":"Shigemoto","first_name":"Ryuichi"},{"first_name":"Robert","last_name":"Stackman","full_name":"Stackman, Robert W"},{"last_name":"Maylie","first_name":"James","full_name":"Maylie, James G"},{"full_name":"Adelman, John P","last_name":"Adelman","first_name":"John"}],"date_updated":"2021-01-12T06:57:56Z","date_created":"2018-12-11T11:58:07Z","volume":14},{"doi":"10.1007/s00220-011-1204-2","date_published":"2011-04-01T00:00:00Z","publication":"Communications in Mathematical Physics","citation":{"chicago":"Erdös, László, and Antti Knowles. “Quantum Diffusion and Eigenfunction Delocalization in a Random Band Matrix Model.” Communications in Mathematical Physics. Springer, 2011. https://doi.org/10.1007/s00220-011-1204-2.","mla":"Erdös, László, and Antti Knowles. “Quantum Diffusion and Eigenfunction Delocalization in a Random Band Matrix Model.” Communications in Mathematical Physics, vol. 303, no. 2, Springer, 2011, pp. 509–54, doi:10.1007/s00220-011-1204-2.","short":"L. Erdös, A. Knowles, Communications in Mathematical Physics 303 (2011) 509–554.","ista":"Erdös L, Knowles A. 2011. Quantum diffusion and eigenfunction delocalization in a random band matrix model. Communications in Mathematical Physics. 303(2), 509–554.","ieee":"L. Erdös and A. Knowles, “Quantum diffusion and eigenfunction delocalization in a random band matrix model,” Communications in Mathematical Physics, vol. 303, no. 2. Springer, pp. 509–554, 2011.","apa":"Erdös, L., & Knowles, A. (2011). Quantum diffusion and eigenfunction delocalization in a random band matrix model. Communications in Mathematical Physics. Springer. https://doi.org/10.1007/s00220-011-1204-2","ama":"Erdös L, Knowles A. Quantum diffusion and eigenfunction delocalization in a random band matrix model. Communications in Mathematical Physics. 2011;303(2):509-554. doi:10.1007/s00220-011-1204-2"},"quality_controlled":0,"page":"509 - 554","day":"01","month":"04","author":[{"first_name":"László","last_name":"Erdös","id":"4DBD5372-F248-11E8-B48F-1D18A9856A87","orcid":"0000-0001-5366-9603","full_name":"László Erdös"},{"full_name":"Knowles, Antti","last_name":"Knowles","first_name":"Antti"}],"date_created":"2018-12-11T11:59:14Z","date_updated":"2021-01-12T06:59:15Z","volume":303,"year":"2011","_id":"2717","status":"public","title":"Quantum diffusion and eigenfunction delocalization in a random band matrix model","publication_status":"published","publisher":"Springer","intvolume":" 303","abstract":[{"lang":"eng","text":"We consider Hermitian and symmetric random band matrices H in d ≥ 1 dimensions. The matrix elements H xy, indexed by, are independent, uniformly distributed random variables if {pipe}x-y{pipe} is less than the band width W, and zero otherwise. We prove that the time evolution of a quantum particle subject to the Hamiltonian H is diffusive on time scales. We also show that the localization length of the eigenvectors of H is larger than a factor W d/6 times the band width. All results are uniform in the size of the matrix. "}],"issue":"2","publist_id":"4175","extern":1,"type":"journal_article"},{"doi":"10.1070/RM2011v066n03ABEH004749","date_published":"2011-01-01T00:00:00Z","quality_controlled":0,"page":"507 - 626","publication":"Russian Mathematical Surveys","main_file_link":[{"url":"http://arxiv.org/abs/1004.0861","open_access":"0"}],"citation":{"ieee":"L. Erdös, “Universality of Wigner random matrices: A survey of recent results,” Russian Mathematical Surveys, vol. 66, no. 3. IOP Publishing Ltd., pp. 507–626, 2011.","apa":"Erdös, L. (2011). Universality of Wigner random matrices: A survey of recent results. Russian Mathematical Surveys. IOP Publishing Ltd. https://doi.org/10.1070/RM2011v066n03ABEH004749","ista":"Erdös L. 2011. Universality of Wigner random matrices: A survey of recent results. Russian Mathematical Surveys. 66(3), 507–626.","ama":"Erdös L. Universality of Wigner random matrices: A survey of recent results. Russian Mathematical Surveys. 2011;66(3):507-626. doi:10.1070/RM2011v066n03ABEH004749","chicago":"Erdös, László. “Universality of Wigner Random Matrices: A Survey of Recent Results.” Russian Mathematical Surveys. IOP Publishing Ltd., 2011. https://doi.org/10.1070/RM2011v066n03ABEH004749.","short":"L. Erdös, Russian Mathematical Surveys 66 (2011) 507–626.","mla":"Erdös, László. “Universality of Wigner Random Matrices: A Survey of Recent Results.” Russian Mathematical Surveys, vol. 66, no. 3, IOP Publishing Ltd., 2011, pp. 507–626, doi:10.1070/RM2011v066n03ABEH004749."},"day":"01","month":"01","date_created":"2018-12-11T11:59:29Z","date_updated":"2019-04-26T07:22:20Z","volume":66,"author":[{"first_name":"László","last_name":"Erdös","id":"4DBD5372-F248-11E8-B48F-1D18A9856A87","orcid":"0000-0001-5366-9603","full_name":"László Erdös"}],"status":"public","publication_status":"published","title":"Universality of Wigner random matrices: A survey of recent results","publisher":"IOP Publishing Ltd.","intvolume":" 66","_id":"2765","year":"2011","extern":1,"abstract":[{"lang":"eng","text":"This is a study of the universality of spectral statistics for large random matrices. Considered are N×N symmetric, Hermitian, or quaternion self-dual random matrices with independent identically distributed entries (Wigner matrices), where the probability distribution of each matrix element is given by a measure v with zero expectation and with subexponential decay. The main result is that the correlation functions of the local eigenvalue statistics in the bulk of the spectrum coincide with those of the Gaussian Orthogonal Ensemble (GOE), the Gaussian Unitary Ensemble (GUE), and the Gaussian Symplectic Ensemble (GSE), respectively, in the limit as N → ∞. This approach is based on a study of the Dyson Brownian motion via a related new dynamics, the local relaxation flow. As a main input, it is established that the density of the eigenvalues converges to the Wigner semicircle law, and this holds even down to the smallest possible scale. Moreover, it is shown that the eigenvectors are completely delocalized. These results hold even without the condition that the matrix elements are identically distributed: only independence is used. In fact, for the matrix elements of the Green function strong estimates are given that imply that the local statistics of any two ensembles in the bulk are identical if the first four moments of the matrix elements match. Universality at the spectral edges requires matching only two moments. A Wigner-type estimate is also proved, and it is shown that the eigenvalues repel each other on arbitrarily small scales."}],"publist_id":"4125","issue":"3","type":"review"},{"year":"2011","_id":"2766","intvolume":" 12","publisher":"Birkhäuser","publication_status":"published","status":"public","title":"Quantum diffusion and delocalization for band matrices with general distribution","author":[{"full_name":"László Erdös","orcid":"0000-0001-5366-9603","id":"4DBD5372-F248-11E8-B48F-1D18A9856A87","last_name":"Erdös","first_name":"László"},{"full_name":"Knowles, Antti","last_name":"Knowles","first_name":"Antti"}],"volume":12,"date_updated":"2021-01-12T06:59:33Z","date_created":"2018-12-11T11:59:29Z","type":"journal_article","publist_id":"4124","issue":"7","abstract":[{"lang":"eng","text":"We consider Hermitian and symmetric random band matrices H in d ≥ dimensions. The matrix elements Hxy, indexed by x,y ∈ Λ ⊂ ℤd are independent and their variances satisfy σ2xy:= E{pipe}Hxy{pipe}2 = W-d f((x-y)/W for some probability density f. We assume that the law of each matrix element Hxy is symmetric and exhibits subexponential decay. We prove that the time evolution of a quantum particle subject to the Hamiltonian H is diffusive on time scales ≪ Wd/3. We also show that the localization length of the eigenvectors of H is larger than a factor Wd/6 times the band width W. All results are uniform in the size {pipe}Λ{pipe} of the matrix. This extends our recent result (Erdo{double acute}s and Knowles in Commun. Math. Phys., 2011) to general band matrices. As another consequence of our proof we show that, for a larger class of random matrices satisfying Σx σ2xy for all y, the largest eigenvalue of H is bounded with high probability by 2+M-2/3+e{open} for any e{open} > 0, where M:= 1/(maxx,y σ2xy)."}],"extern":1,"citation":{"ama":"Erdös L, Knowles A. Quantum diffusion and delocalization for band matrices with general distribution. Annales Henri Poincare. 2011;12(7):1227-1319. doi:10.1007/s00023-011-0104-5","ista":"Erdös L, Knowles A. 2011. Quantum diffusion and delocalization for band matrices with general distribution. Annales Henri Poincare. 12(7), 1227–1319.","apa":"Erdös, L., & Knowles, A. (2011). Quantum diffusion and delocalization for band matrices with general distribution. Annales Henri Poincare. Birkhäuser. https://doi.org/10.1007/s00023-011-0104-5","ieee":"L. Erdös and A. Knowles, “Quantum diffusion and delocalization for band matrices with general distribution,” Annales Henri Poincare, vol. 12, no. 7. Birkhäuser, pp. 1227–1319, 2011.","mla":"Erdös, László, and Antti Knowles. “Quantum Diffusion and Delocalization for Band Matrices with General Distribution.” Annales Henri Poincare, vol. 12, no. 7, Birkhäuser, 2011, pp. 1227–319, doi:10.1007/s00023-011-0104-5.","short":"L. Erdös, A. Knowles, Annales Henri Poincare 12 (2011) 1227–1319.","chicago":"Erdös, László, and Antti Knowles. “Quantum Diffusion and Delocalization for Band Matrices with General Distribution.” Annales Henri Poincare. Birkhäuser, 2011. https://doi.org/10.1007/s00023-011-0104-5."},"publication":"Annales Henri Poincare","page":"1227 - 1319","quality_controlled":0,"date_published":"2011-11-01T00:00:00Z","doi":"10.1007/s00023-011-0104-5","day":"01","month":"11"},{"month":"07","day":"01","citation":{"ista":"Erdös L, Schlein B, Yau H. 2011. Universality of random matrices and local relaxation flow. Inventiones Mathematicae. 185(1), 75–119.","ieee":"L. Erdös, B. Schlein, and H. Yau, “Universality of random matrices and local relaxation flow,” Inventiones Mathematicae, vol. 185, no. 1. Springer, pp. 75–119, 2011.","apa":"Erdös, L., Schlein, B., & Yau, H. (2011). Universality of random matrices and local relaxation flow. Inventiones Mathematicae. Springer. https://doi.org/10.1007/s00222-010-0302-7","ama":"Erdös L, Schlein B, Yau H. Universality of random matrices and local relaxation flow. Inventiones Mathematicae. 2011;185(1):75-119. doi:10.1007/s00222-010-0302-7","chicago":"Erdös, László, Benjamin Schlein, and Horng Yau. “Universality of Random Matrices and Local Relaxation Flow.” Inventiones Mathematicae. Springer, 2011. https://doi.org/10.1007/s00222-010-0302-7.","mla":"Erdös, László, et al. “Universality of Random Matrices and Local Relaxation Flow.” Inventiones Mathematicae, vol. 185, no. 1, Springer, 2011, pp. 75–119, doi:10.1007/s00222-010-0302-7.","short":"L. Erdös, B. Schlein, H. Yau, Inventiones Mathematicae 185 (2011) 75–119."},"publication":"Inventiones Mathematicae","page":"75 - 119","quality_controlled":0,"doi":"10.1007/s00222-010-0302-7","date_published":"2011-07-01T00:00:00Z","type":"journal_article","publist_id":"4126","issue":"1","abstract":[{"lang":"eng","text":"Consider the Dyson Brownian motion with parameter β, where β=1,2,4 corresponds to the eigenvalue flows for the eigenvalues of symmetric, hermitian and quaternion self-dual ensembles. For any β≥1, we prove that the relaxation time to local equilibrium for the Dyson Brownian motion is bounded above by N -ζ for some ζ> 0. The proof is based on an estimate of the entropy flow of the Dyson Brownian motion w. r. t. a "pseudo equilibrium measure". As an application of this estimate, we prove that the eigenvalue spacing statistics in the bulk of the spectrum for N×N symmetric Wigner ensemble is the same as that of the Gaussian Orthogonal Ensemble (GOE) in the limit N→∞. The assumptions on the probability distribution of the matrix elements of the Wigner ensemble are a subexponential decay and some minor restriction on the support."}],"extern":1,"_id":"2764","year":"2011","publisher":"Springer","intvolume":" 185","title":"Universality of random matrices and local relaxation flow","status":"public","publication_status":"published","author":[{"full_name":"László Erdös","orcid":"0000-0001-5366-9603","id":"4DBD5372-F248-11E8-B48F-1D18A9856A87","last_name":"Erdös","first_name":"László"},{"full_name":"Schlein, Benjamin","first_name":"Benjamin","last_name":"Schlein"},{"full_name":"Yau, Horng-Tzer","last_name":"Yau","first_name":"Horng"}],"volume":185,"date_updated":"2021-01-12T06:59:32Z","date_created":"2018-12-11T11:59:29Z"},{"date_published":"2011-07-08T00:00:00Z","doi":"10.1126/science.1203223","citation":{"ieee":"K. Avila, D. Moxey, A. De Lózar, M. Avila, D. Barkley, and B. Hof, “The onset of turbulence in pipe flow,” Science, vol. 333, no. 6039. American Association for the Advancement of Science, pp. 192–196, 2011.","apa":"Avila, K., Moxey, D., De Lózar, A., Avila, M., Barkley, D., & Hof, B. (2011). The onset of turbulence in pipe flow. Science. American Association for the Advancement of Science. https://doi.org/10.1126/science.1203223","ista":"Avila K, Moxey D, De Lózar A, Avila M, Barkley D, Hof B. 2011. The onset of turbulence in pipe flow. Science. 333(6039), 192–196.","ama":"Avila K, Moxey D, De Lózar A, Avila M, Barkley D, Hof B. The onset of turbulence in pipe flow. Science. 2011;333(6039):192-196. doi:10.1126/science.1203223","chicago":"Avila, Kerstin, David Moxey, Alberto De Lózar, Marc Avila, Dwight Barkley, and Björn Hof. “The Onset of Turbulence in Pipe Flow.” Science. American Association for the Advancement of Science, 2011. https://doi.org/10.1126/science.1203223.","short":"K. Avila, D. Moxey, A. De Lózar, M. Avila, D. Barkley, B. Hof, Science 333 (2011) 192–196.","mla":"Avila, Kerstin, et al. “The Onset of Turbulence in Pipe Flow.” Science, vol. 333, no. 6039, American Association for the Advancement of Science, 2011, pp. 192–96, doi:10.1126/science.1203223."},"publication":"Science","page":"192 - 196","quality_controlled":0,"day":"08","month":"07","author":[{"last_name":"Avila","first_name":"Kerstin","full_name":"Avila, Kerstin"},{"first_name":"David","last_name":"Moxey","full_name":"Moxey, David"},{"last_name":"De Lózar","first_name":"Alberto","full_name":"de Lózar, Alberto"},{"last_name":"Avila","first_name":"Marc","full_name":"Avila, Marc"},{"first_name":"Dwight","last_name":"Barkley","full_name":"Barkley, Dwight"},{"id":"3A374330-F248-11E8-B48F-1D18A9856A87","orcid":"0000-0003-2057-2754","first_name":"Björn","last_name":"Hof","full_name":"Björn Hof"}],"volume":333,"date_updated":"2021-01-12T06:59:47Z","date_created":"2018-12-11T11:59:39Z","_id":"2799","year":"2011","intvolume":" 333","publisher":"American Association for the Advancement of Science","publication_status":"published","status":"public","title":"The onset of turbulence in pipe flow","issue":"6039","publist_id":"4090","abstract":[{"lang":"eng","text":"Shear flows undergo a sudden transition from laminar to turbulent motion as the velocity increases, and the onset of turbulence radically changes transport efficiency and mixing properties. Even for the well-studied case of pipe flow, it has not been possible to determine at what Reynolds number the motion will be either persistently turbulent or ultimately laminar. We show that in pipes, turbulence that is transient at low Reynolds numbers becomes sustained at a distinct critical point. Through extensive experiments and computer simulations, we were able to identify and characterize the processes ultimately responsible for sustaining turbulence. In contrast to the classical Landau-Ruelle-Takens view that turbulence arises from an increase in the temporal complexity of fluid motion, here, spatial proliferation of chaotic domains is the decisive process and intrinsic to the nature of fluid turbulence."}],"extern":1,"type":"journal_article"},{"abstract":[{"text":"In shear flows, turbulence first occurs in the form of localized structures (puffs/spots) surrounded by laminar fluid. We here investigate such spatially intermittent flows in a pipe experiment showing that turbulent puffs have a well-defined interaction distance, which sets their minimum spacing as well as the maximum observable turbulent fraction. Two methodologies are employed. Starting from a laminar flow, puffs are first created by locally injecting a jet of fluid through the pipe wall. When the perturbation is applied periodically at low frequencies, as expected, a regular sequence of puffs is observed where the puff spacing is given by the ratio of the mean flow speed to the perturbation frequency. At large frequencies however puffs are found to interact and annihilate each other. Varying the perturbation frequency, an interaction distance is determined which sets the highest possible turbulence fraction. This enables us to establish an upper bound for the friction factor in the transitional regime, which provides a well-defined link between the Blasius and the Hagen-Poiseuille friction laws. In the second set of experiments, the Reynolds number is reduced suddenly from fully turbulent to the intermittent regime. The resulting flow reorganizes itself to a sequence of constant size puffs which, unlike in Couette and Taylor–Couette flow are randomly spaced. The minimum distance between the turbulent patches is identical to the puff interaction length. The puff interaction length is found to be in agreement with the wavelength of regular stripe and spiral patterns in plane Couette and Taylor–Couette flow.","lang":"eng"}],"publist_id":"4089","extern":1,"type":"journal_article","author":[{"last_name":"Samanta","first_name":"Devranjan","full_name":"Samanta, Devranjan"},{"last_name":"De Lózar","first_name":"Alberto","full_name":"de Lózar, Alberto"},{"full_name":"Björn Hof","orcid":"0000-0003-2057-2754","id":"3A374330-F248-11E8-B48F-1D18A9856A87","last_name":"Hof","first_name":"Björn"}],"date_updated":"2021-01-12T06:59:48Z","date_created":"2018-12-11T11:59:40Z","volume":681,"_id":"2800","year":"2011","title":"Experimental investigation of laminar turbulent intermittency in pipe flow","publication_status":"published","status":"public","publisher":"Cambridge University Press","intvolume":" 681","day":"25","month":"08","date_published":"2011-08-25T00:00:00Z","doi":"10.1017/jfm.2011.189","publication":"Journal of Fluid Mechanics","citation":{"mla":"Samanta, Devranjan, et al. “Experimental Investigation of Laminar Turbulent Intermittency in Pipe Flow.” Journal of Fluid Mechanics, vol. 681, Cambridge University Press, 2011, pp. 193–204, doi:10.1017/jfm.2011.189.","short":"D. Samanta, A. De Lózar, B. Hof, Journal of Fluid Mechanics 681 (2011) 193–204.","chicago":"Samanta, Devranjan, Alberto De Lózar, and Björn Hof. “Experimental Investigation of Laminar Turbulent Intermittency in Pipe Flow.” Journal of Fluid Mechanics. Cambridge University Press, 2011. https://doi.org/10.1017/jfm.2011.189.","ama":"Samanta D, De Lózar A, Hof B. Experimental investigation of laminar turbulent intermittency in pipe flow. Journal of Fluid Mechanics. 2011;681:193-204. doi:10.1017/jfm.2011.189","ista":"Samanta D, De Lózar A, Hof B. 2011. Experimental investigation of laminar turbulent intermittency in pipe flow. Journal of Fluid Mechanics. 681, 193–204.","apa":"Samanta, D., De Lózar, A., & Hof, B. (2011). Experimental investigation of laminar turbulent intermittency in pipe flow. Journal of Fluid Mechanics. Cambridge University Press. https://doi.org/10.1017/jfm.2011.189","ieee":"D. Samanta, A. De Lózar, and B. Hof, “Experimental investigation of laminar turbulent intermittency in pipe flow,” Journal of Fluid Mechanics, vol. 681. Cambridge University Press, pp. 193–204, 2011."},"quality_controlled":0,"page":"193 - 204"},{"alternative_title":["Journal of Physics: Conference Series"],"type":"conference","extern":1,"publist_id":"4088","issue":"5","abstract":[{"text":"Turbulent puffs in pipe flow are characterized by a sharp laminar-turbulent interface at the trailing edge and a more diffused leading interface. It is known that these laminar-turbulent interfaces propagate at a speed that is approximately equal to the flow rate. Our results from direct numerical simulation show that, locally, the interface velocity relative to the fluid (i) counteracts the advection due to the laminar velocity profile so that the puff can preserve its characteristic overall shape, (ii) is very small in magnitude, but involves a large interface area so that the global propagation velocity relative to the mean flow can be large and (iii) is determined by both inertial and viscous effects. The analysis provides some new insights into the mechanisms that sustain or expand localized turbulence and might be relevant for the design of new control strategies.","lang":"eng"}],"intvolume":" 318","publisher":"IOP Publishing Ltd.","publication_status":"published","title":"A Lagrangian approach to the interface velocity of turbulent puffs in pipe flow","status":"public","year":"2011","_id":"2801","volume":318,"date_updated":"2019-04-26T07:22:20Z","date_created":"2018-12-11T11:59:40Z","author":[{"full_name":"Holzner, Markus","first_name":"Markus","last_name":"Holzner"},{"full_name":"Avila, Marc","last_name":"Avila","first_name":"Marc"},{"last_name":"De Lózar","first_name":"Alberto","full_name":"de Lózar, Alberto"},{"full_name":"Björn Hof","id":"3A374330-F248-11E8-B48F-1D18A9856A87","orcid":"0000-0003-2057-2754","first_name":"Björn","last_name":"Hof"}],"month":"09","day":"01","quality_controlled":0,"citation":{"ista":"Holzner M, Avila M, De Lózar A, Hof B. 2011. A Lagrangian approach to the interface velocity of turbulent puffs in pipe flow. ETC13: European Turbulence Conference, Journal of Physics: Conference Series, vol. 318.","apa":"Holzner, M., Avila, M., De Lózar, A., & Hof, B. (2011). A Lagrangian approach to the interface velocity of turbulent puffs in pipe flow (Vol. 318). Presented at the ETC13: European Turbulence Conference, IOP Publishing Ltd. https://doi.org/10.1088/1742-6596/318/5/052031","ieee":"M. Holzner, M. Avila, A. De Lózar, and B. Hof, “A Lagrangian approach to the interface velocity of turbulent puffs in pipe flow,” presented at the ETC13: European Turbulence Conference, 2011, vol. 318, no. 5.","ama":"Holzner M, Avila M, De Lózar A, Hof B. A Lagrangian approach to the interface velocity of turbulent puffs in pipe flow. In: Vol 318. IOP Publishing Ltd.; 2011. doi:10.1088/1742-6596/318/5/052031","chicago":"Holzner, Markus, Marc Avila, Alberto De Lózar, and Björn Hof. “A Lagrangian Approach to the Interface Velocity of Turbulent Puffs in Pipe Flow,” Vol. 318. IOP Publishing Ltd., 2011. https://doi.org/10.1088/1742-6596/318/5/052031.","mla":"Holzner, Markus, et al. A Lagrangian Approach to the Interface Velocity of Turbulent Puffs in Pipe Flow. Vol. 318, no. 5, IOP Publishing Ltd., 2011, doi:10.1088/1742-6596/318/5/052031.","short":"M. Holzner, M. Avila, A. De Lózar, B. Hof, in:, IOP Publishing Ltd., 2011."},"doi":"10.1088/1742-6596/318/5/052031","date_published":"2011-09-01T00:00:00Z","conference":{"name":"ETC13: European Turbulence Conference"}},{"date_published":"2011-08-01T00:00:00Z","doi":"10.1111/j.1365-313X.2011.04621.x","page":"622 - 634","quality_controlled":0,"citation":{"ama":"Gallego Bartolomé J, Arana M, Vandenbussche F, et al. Hierarchy of hormone action controlling apical hook development in Arabidopsis. Plant Journal. 2011;67(4):622-634. doi:10.1111/j.1365-313X.2011.04621.x","apa":"Gallego Bartolomé, J., Arana, M., Vandenbussche, F., Žádníková, P., Minguet, E., Guardiola, V., … Blázquez, M. (2011). Hierarchy of hormone action controlling apical hook development in Arabidopsis. Plant Journal. Wiley-Blackwell. https://doi.org/10.1111/j.1365-313X.2011.04621.x","ieee":"J. Gallego Bartolomé et al., “Hierarchy of hormone action controlling apical hook development in Arabidopsis,” Plant Journal, vol. 67, no. 4. Wiley-Blackwell, pp. 622–634, 2011.","ista":"Gallego Bartolomé J, Arana M, Vandenbussche F, Žádníková P, Minguet E, Guardiola V, Van Der Straeten D, Benková E, Alabadí D, Blázquez M. 2011. Hierarchy of hormone action controlling apical hook development in Arabidopsis. Plant Journal. 67(4), 622–634.","short":"J. Gallego Bartolomé, M. Arana, F. Vandenbussche, P. Žádníková, E. Minguet, V. Guardiola, D. Van Der Straeten, E. Benková, D. Alabadí, M. Blázquez, Plant Journal 67 (2011) 622–634.","mla":"Gallego Bartolomé, Javier, et al. “Hierarchy of Hormone Action Controlling Apical Hook Development in Arabidopsis.” Plant Journal, vol. 67, no. 4, Wiley-Blackwell, 2011, pp. 622–34, doi:10.1111/j.1365-313X.2011.04621.x.","chicago":"Gallego Bartolomé, Javier, María Arana, Filip Vandenbussche, Petra Žádníková, Eugenio Minguet, Vicente Guardiola, Dominique Van Der Straeten, Eva Benková, David Alabadí, and Miguel Blázquez. “Hierarchy of Hormone Action Controlling Apical Hook Development in Arabidopsis.” Plant Journal. Wiley-Blackwell, 2011. https://doi.org/10.1111/j.1365-313X.2011.04621.x."},"publication":"Plant Journal","month":"08","day":"01","volume":67,"date_updated":"2021-01-12T07:00:24Z","date_created":"2018-12-11T12:00:04Z","author":[{"full_name":"Gallego-Bartolomé, Javier","last_name":"Gallego Bartolomé","first_name":"Javier"},{"last_name":"Arana","first_name":"María","full_name":"Arana, María V"},{"first_name":"Filip","last_name":"Vandenbussche","full_name":"Vandenbussche, Filip"},{"first_name":"Petra","last_name":"Žádníková","full_name":"Žádníková, Petra"},{"last_name":"Minguet","first_name":"Eugenio","full_name":"Minguet, Eugenio G"},{"full_name":"Guardiola, Vicente","first_name":"Vicente","last_name":"Guardiola"},{"first_name":"Dominique","last_name":"Van Der Straeten","full_name":"Van Der Straeten, Dominique"},{"full_name":"Eva Benková","id":"38F4F166-F248-11E8-B48F-1D18A9856A87","orcid":"0000-0002-8510-9739","first_name":"Eva","last_name":"Benková"},{"first_name":"David","last_name":"Alabadí","full_name":"Alabadí, David"},{"full_name":"Blázquez, Miguel A","last_name":"Blázquez","first_name":"Miguel"}],"publisher":"Wiley-Blackwell","intvolume":" 67","title":"Hierarchy of hormone action controlling apical hook development in Arabidopsis","status":"public","publication_status":"published","_id":"2874","year":"2011","extern":1,"publist_id":"3891","issue":"4","abstract":[{"text":"The apical hook develops in the upper part of the hypocotyl when seeds buried in the soil germinate, and serves to protect cotyledons and the shoot apical meristem from possible damage caused by pushing through the soil. The curvature is formed through differential cell growth that occurs at the two opposite sides of the hypocotyl, and it is established by a gradient of auxin activity and refined by the coordinated action of auxin and ethylene. Here we show that gibberellins (GAs) promote hook development through the transcriptional regulation of several genes of the ethylene and auxin pathways in Arabidopsis. The level of GA activity determines the speed of hook formation and the extent of the curvature during the formation phase independently of ethylene, probably by modulating auxin transport and response through HLS1, PIN3, and PIN7. Moreover, GAs cooperate with ethylene in preventing hook opening, in part through the induction of ethylene production mediated by ACS5/ETO2 and ACS8.","lang":"eng"}],"type":"journal_article"},{"type":"journal_article","issue":"1","publist_id":"3894","abstract":[{"text":"Despite their relatively simple appearance, roots are incredibly complex organs that are highly adapted to differing environments. Many aspects of root development are co-ordinated by subtle spatial differences in the concentrations of the phytohormones auxin and cytokinin. Events from the formation of a root during embryogenesis to the determination of the network of lateral roots are controlled by interactions between these hormones. Recently, interactions have been defined where auxin signaling promotes the expression of cytokinin signaling inhibitors, cytokinin signaling promotes the expression of auxin signaling inhibitors and finally where cytokinin signaling regulates the complex network of auxin transport proteins to position zones of high auxin signaling. We are witnessing a period of discovery in which we are beginning to understand how these hormonal pathways communicate to regulate root formation.","lang":"eng"}],"extern":1,"_id":"2871","year":"2011","intvolume":" 14","publisher":"Elsevier","publication_status":"published","title":"Sending mixed messages: Auxin-cytokinin crosstalk in roots","status":"public","author":[{"full_name":"Bishopp, Anthony","first_name":"Anthony","last_name":"Bishopp"},{"full_name":"Eva Benková","orcid":"0000-0002-8510-9739","id":"38F4F166-F248-11E8-B48F-1D18A9856A87","last_name":"Benková","first_name":"Eva"},{"last_name":"Helariutta","first_name":"Ykä","full_name":"Helariutta, Ykä"}],"volume":14,"date_updated":"2021-01-12T07:00:23Z","date_created":"2018-12-11T12:00:03Z","day":"01","month":"02","citation":{"short":"A. Bishopp, E. Benková, Y. Helariutta, Current Opinion in Plant Biology 14 (2011) 10–16.","mla":"Bishopp, Anthony, et al. “Sending Mixed Messages: Auxin-Cytokinin Crosstalk in Roots.” Current Opinion in Plant Biology, vol. 14, no. 1, Elsevier, 2011, pp. 10–16, doi:10.1016/j.pbi.2010.08.014.","chicago":"Bishopp, Anthony, Eva Benková, and Ykä Helariutta. “Sending Mixed Messages: Auxin-Cytokinin Crosstalk in Roots.” Current Opinion in Plant Biology. Elsevier, 2011. https://doi.org/10.1016/j.pbi.2010.08.014.","ama":"Bishopp A, Benková E, Helariutta Y. Sending mixed messages: Auxin-cytokinin crosstalk in roots. Current Opinion in Plant Biology. 2011;14(1):10-16. doi:10.1016/j.pbi.2010.08.014","ieee":"A. Bishopp, E. Benková, and Y. Helariutta, “Sending mixed messages: Auxin-cytokinin crosstalk in roots,” Current Opinion in Plant Biology, vol. 14, no. 1. Elsevier, pp. 10–16, 2011.","apa":"Bishopp, A., Benková, E., & Helariutta, Y. (2011). Sending mixed messages: Auxin-cytokinin crosstalk in roots. Current Opinion in Plant Biology. Elsevier. https://doi.org/10.1016/j.pbi.2010.08.014","ista":"Bishopp A, Benková E, Helariutta Y. 2011. Sending mixed messages: Auxin-cytokinin crosstalk in roots. Current Opinion in Plant Biology. 14(1), 10–16."},"publication":"Current Opinion in Plant Biology","page":"10 - 16","quality_controlled":0,"doi":"10.1016/j.pbi.2010.08.014","date_published":"2011-02-01T00:00:00Z"},{"month":"03","day":"01","publication":"Evolution; International Journal of Organic Evolution","citation":{"ama":"Paixao T, Phadke S, Azevedo R, Zufall R. Sex ratio evolution under probabilistic sex determination. Evolution; International Journal of Organic Evolution. 2011;65(7):2050-2060. doi:10.1111/j.1558-5646.2011.01266.x","ista":"Paixao T, Phadke S, Azevedo R, Zufall R. 2011. Sex ratio evolution under probabilistic sex determination. Evolution; International Journal of Organic Evolution. 65(7), 2050–2060.","ieee":"T. Paixao, S. Phadke, R. Azevedo, and R. Zufall, “Sex ratio evolution under probabilistic sex determination,” Evolution; International Journal of Organic Evolution, vol. 65, no. 7. Wiley-Blackwell, pp. 2050–2060, 2011.","apa":"Paixao, T., Phadke, S., Azevedo, R., & Zufall, R. (2011). Sex ratio evolution under probabilistic sex determination. Evolution; International Journal of Organic Evolution. Wiley-Blackwell. https://doi.org/10.1111/j.1558-5646.2011.01266.x","mla":"Paixao, Tiago, et al. “Sex Ratio Evolution under Probabilistic Sex Determination.” Evolution; International Journal of Organic Evolution, vol. 65, no. 7, Wiley-Blackwell, 2011, pp. 2050–60, doi:10.1111/j.1558-5646.2011.01266.x.","short":"T. Paixao, S. Phadke, R. Azevedo, R. Zufall, Evolution; International Journal of Organic Evolution 65 (2011) 2050–2060.","chicago":"Paixao, Tiago, Sujal Phadke, Ricardo Azevedo, and Rebecca Zufall. “Sex Ratio Evolution under Probabilistic Sex Determination.” Evolution; International Journal of Organic Evolution. Wiley-Blackwell, 2011. https://doi.org/10.1111/j.1558-5646.2011.01266.x."},"quality_controlled":0,"page":"2050 - 2060","doi":"10.1111/j.1558-5646.2011.01266.x","date_published":"2011-03-01T00:00:00Z","type":"journal_article","abstract":[{"text":"Sex allocation theory has been remarkably successful at explaining the prevalence of even sex ratios in natural populations and at identifying specific conditions that can result in biased sex ratios. Much of this theory focuses on parental sex determination (SD) strategies. Here, we consider instead the evolutionary causes and consequences of mixed offspring SD strategies, in which the genotype of an individual determines not its sex, but the probability of developing one of multiple sexes. We find that alleles specifying mixed offspring SD strategies can generally outcompete alleles that specify pure strategies, but generate constraints that may prevent a population from reaching an even sex ratio. We use our model to analyze sex ratios in natural populations of Tetrahymena thermophila, a ciliate with seven sexes determined by mixed SD alleles. We show that probabilistic SD is sufficient to account for the occurrence of skewed sex ratios in natural populations of T. thermophila, provided that their effective population sizes are small. Our results highlight the importance of genetic drift in sex ratio evolution and suggest that mixed offspring SD strategies should be more common than currently thought.","lang":"eng"}],"issue":"7","publist_id":"3860","extern":1,"year":"2011","_id":"2898","publication_status":"published","status":"public","title":"Sex ratio evolution under probabilistic sex determination","publisher":"Wiley-Blackwell","intvolume":" 65","author":[{"full_name":"Tiago Paixao","orcid":"0000-0003-2361-3953","id":"2C5658E6-F248-11E8-B48F-1D18A9856A87","last_name":"Paixao","first_name":"Tiago"},{"first_name":"Sujal","last_name":"Phadke","full_name":"Phadke, Sujal S"},{"full_name":"Azevedo, Ricardo B","first_name":"Ricardo","last_name":"Azevedo"},{"full_name":"Zufall, Rebecca A","last_name":"Zufall","first_name":"Rebecca"}],"date_created":"2018-12-11T12:00:13Z","date_updated":"2021-01-12T07:00:33Z","volume":65},{"extern":1,"issue":"7","publist_id":"3861","type":"journal_article","date_created":"2018-12-11T12:00:13Z","date_updated":"2021-01-12T07:00:33Z","volume":6,"author":[{"orcid":"0000-0003-2361-3953","id":"2C5658E6-F248-11E8-B48F-1D18A9856A87","last_name":"Paixao","first_name":"Tiago","full_name":"Tiago Paixao"},{"full_name":"Azevedo, Ricardo B","last_name":"Azevedo","first_name":"Ricardo"}],"publication_status":"published","status":"public","title":"Redundancy and the Evolution of Cis Regulatory Element Multiplicity","publisher":"Public Library of Science","intvolume":" 6","year":"2011","_id":"2897","acknowledgement":"TFs regulate gene expression by binding to specific sequences in the promoter regions of their target genes. Promoters often contain multiple copies of the same TF binding sites. How does this multiplicity evolve? One possibility is that individuals with multiple, redundant binding sites have higher fitness. However, nonadaptive processes are also likely to be important. Here, we develop a mathematical model of the evolution of TF binding sites to help us disentangle how different evolutionary mechanisms contribute to the evolution of binding site redundancy and multiplicity. We show that recombination is expected to promote the evolution of multiple binding sites. This prediction is corroborated by genome-wide data from yeast. Another important factor in the evolution of multiplicity predicted in our analysis is TF promiscuity, that is, the ability of a TF to bind to multiple sequences. In addition, our analysis indicated that direct selection can have large effects on the evolution of redundancy and multiplicity. Data from yeast identified selection for changes in expression level as a candidate mechanism for the evolution of multiple binding sites. We conclude that, although selection may play a major role in the evolution of multiplicity in regulatory regions, nonadaptive forces can also lead to high levels of multiplicity.","month":"01","day":"01","date_published":"2011-01-01T00:00:00Z","doi":"10.1371/journal.pcbi.1000848","quality_controlled":0,"publication":"PLoS Computational Biology","tmp":{"name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)","legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode","short":"CC BY (4.0)","image":"/images/cc_by.png"},"citation":{"ama":"Paixao T, Azevedo R. Redundancy and the Evolution of Cis Regulatory Element Multiplicity. PLoS Computational Biology. 2011;6(7). doi:10.1371/journal.pcbi.1000848","apa":"Paixao, T., & Azevedo, R. (2011). Redundancy and the Evolution of Cis Regulatory Element Multiplicity. PLoS Computational Biology. Public Library of Science. https://doi.org/10.1371/journal.pcbi.1000848","ieee":"T. Paixao and R. Azevedo, “Redundancy and the Evolution of Cis Regulatory Element Multiplicity,” PLoS Computational Biology, vol. 6, no. 7. Public Library of Science, 2011.","ista":"Paixao T, Azevedo R. 2011. Redundancy and the Evolution of Cis Regulatory Element Multiplicity. PLoS Computational Biology. 6(7).","short":"T. Paixao, R. Azevedo, PLoS Computational Biology 6 (2011).","mla":"Paixao, Tiago, and Ricardo Azevedo. “Redundancy and the Evolution of Cis Regulatory Element Multiplicity.” PLoS Computational Biology, vol. 6, no. 7, Public Library of Science, 2011, doi:10.1371/journal.pcbi.1000848.","chicago":"Paixao, Tiago, and Ricardo Azevedo. “Redundancy and the Evolution of Cis Regulatory Element Multiplicity.” PLoS Computational Biology. Public Library of Science, 2011. https://doi.org/10.1371/journal.pcbi.1000848."}},{"month":"01","day":"01","quality_controlled":0,"publication":"Markov Random Fields for Vision and Image Processing","citation":{"ama":"Vicente S, Kolmogorov V, Rother C. Graph-cut Based Image Segmentation with Connectivity Priors. In: Blake A, Kohli P, Rother C, eds. Markov Random Fields for Vision and Image Processing. Massachusetts Institute of Technology Press; 2011.","ista":"Vicente S, Kolmogorov V, Rother C. 2011.Graph-cut Based Image Segmentation with Connectivity Priors. In: Markov Random Fields for Vision and Image Processing. .","ieee":"S. Vicente, V. Kolmogorov, and C. Rother, “Graph-cut Based Image Segmentation with Connectivity Priors,” in Markov Random Fields for Vision and Image Processing, A. Blake, P. Kohli, and C. Rother, Eds. Massachusetts Institute of Technology Press, 2011.","apa":"Vicente, S., Kolmogorov, V., & Rother, C. (2011). Graph-cut Based Image Segmentation with Connectivity Priors. In A. Blake, P. Kohli, & C. Rother (Eds.), Markov Random Fields for Vision and Image Processing. Massachusetts Institute of Technology Press.","mla":"Vicente, Sara, et al. “Graph-Cut Based Image Segmentation with Connectivity Priors.” Markov Random Fields for Vision and Image Processing, edited by Andrew Blake et al., Massachusetts Institute of Technology Press, 2011.","short":"S. Vicente, V. Kolmogorov, C. Rother, in:, A. Blake, P. Kohli, C. Rother (Eds.), Markov Random Fields for Vision and Image Processing, Massachusetts Institute of Technology Press, 2011.","chicago":"Vicente, Sara, Vladimir Kolmogorov, and Carsten Rother. “Graph-Cut Based Image Segmentation with Connectivity Priors.” In Markov Random Fields for Vision and Image Processing, edited by Andrew Blake, Pushmeet Kohli, and Carsten Rother. Massachusetts Institute of Technology Press, 2011."},"date_published":"2011-01-01T00:00:00Z","type":"book_chapter","extern":1,"publist_id":"3815","status":"public","publication_status":"published","title":"Graph-cut Based Image Segmentation with Connectivity Priors","publisher":"Massachusetts Institute of Technology Press","editor":[{"full_name":"Blake, Andrew","last_name":"Blake","first_name":"Andrew"},{"full_name":"Kohli, Pushmeet","first_name":"Pushmeet","last_name":"Kohli"},{"first_name":"Carsten","last_name":"Rother","full_name":"Rother, Carsten"}],"_id":"2922","year":"2011","date_created":"2018-12-11T12:00:21Z","date_updated":"2021-01-12T07:00:43Z","author":[{"last_name":"Vicente","first_name":"Sara","full_name":"Vicente, Sara"},{"id":"3D50B0BA-F248-11E8-B48F-1D18A9856A87","first_name":"Vladimir","last_name":"Kolmogorov","full_name":"Vladimir Kolmogorov"},{"last_name":"Rother","first_name":"Carsten","full_name":"Rother, Carsten"}]},{"citation":{"short":"M.P. Kumar, V. Kolmogorov, P. Torr, in:, A. Blake, P. Kohli, C. Rother (Eds.), Markov Random Fields for Vision and Image Processing, Massachusetts Institute of Technology Press, 2011.","mla":"Kumar, M. Pawan, et al. “Analyzing Convex Relaxations for MAP Estimation.” Markov Random Fields for Vision and Image Processing, edited by Andrew Blake et al., Massachusetts Institute of Technology Press, 2011.","chicago":"Kumar, M Pawan, Vladimir Kolmogorov, and Philip Torr. “Analyzing Convex Relaxations for MAP Estimation.” In Markov Random Fields for Vision and Image Processing, edited by Andrew Blake, Pushmeet Kohli, and Carsten Rother. Massachusetts Institute of Technology Press, 2011.","ama":"Kumar MP, Kolmogorov V, Torr P. Analyzing Convex Relaxations for MAP Estimation. In: Blake A, Kohli P, Rother C, eds. Markov Random Fields for Vision and Image Processing. Massachusetts Institute of Technology Press; 2011.","ieee":"M. P. Kumar, V. Kolmogorov, and P. Torr, “Analyzing Convex Relaxations for MAP Estimation,” in Markov Random Fields for Vision and Image Processing, A. Blake, P. Kohli, and C. Rother, Eds. Massachusetts Institute of Technology Press, 2011.","apa":"Kumar, M. P., Kolmogorov, V., & Torr, P. (2011). Analyzing Convex Relaxations for MAP Estimation. In A. Blake, P. Kohli, & C. Rother (Eds.), Markov Random Fields for Vision and Image Processing. Massachusetts Institute of Technology Press.","ista":"Kumar MP, Kolmogorov V, Torr P. 2011.Analyzing Convex Relaxations for MAP Estimation. In: Markov Random Fields for Vision and Image Processing. ."},"publication":"Markov Random Fields for Vision and Image Processing","quality_controlled":0,"date_published":"2011-01-01T00:00:00Z","month":"01","day":"01","_id":"2923","year":"2011","editor":[{"last_name":"Blake","first_name":"Andrew","full_name":"Blake, Andrew"},{"full_name":"Kohli, Pushmeet","first_name":"Pushmeet","last_name":"Kohli"},{"full_name":"Rother, Carsten","last_name":"Rother","first_name":"Carsten"}],"publisher":"Massachusetts Institute of Technology Press","status":"public","title":"Analyzing Convex Relaxations for MAP Estimation","publication_status":"published","author":[{"full_name":"Kumar, M Pawan","last_name":"Kumar","first_name":"M Pawan"},{"full_name":"Vladimir Kolmogorov","id":"3D50B0BA-F248-11E8-B48F-1D18A9856A87","first_name":"Vladimir","last_name":"Kolmogorov"},{"last_name":"Torr","first_name":"Philip","full_name":"Torr, Philip H"}],"date_updated":"2021-01-12T07:00:43Z","date_created":"2018-12-11T12:00:21Z","type":"book_chapter","publist_id":"3814","extern":1},{"day":"01","month":"01","publication":"Markov Random Fields for Vision and Image Processing","citation":{"chicago":"Criminisi, Antonio, Geoffrey Cross, Andrew Blake, and Vladimir Kolmogorov. “Bilayer Segmentation of Video.” In Markov Random Fields for Vision and Image Processing, edited by Andrew Blake, Pushmeet Kohli, and Carsten Rother. Massachusetts Institute of Technology Press, 2011.","mla":"Criminisi, Antonio, et al. “Bilayer Segmentation of Video.” Markov Random Fields for Vision and Image Processing, edited by Andrew Blake et al., Massachusetts Institute of Technology Press, 2011.","short":"A. Criminisi, G. Cross, A. Blake, V. Kolmogorov, in:, A. Blake, P. Kohli, C. Rother (Eds.), Markov Random Fields for Vision and Image Processing, Massachusetts Institute of Technology Press, 2011.","ista":"Criminisi A, Cross G, Blake A, Kolmogorov V. 2011.Bilayer Segmentation of Video. In: Markov Random Fields for Vision and Image Processing. .","ieee":"A. Criminisi, G. Cross, A. Blake, and V. Kolmogorov, “Bilayer Segmentation of Video,” in Markov Random Fields for Vision and Image Processing, A. Blake, P. Kohli, and C. Rother, Eds. Massachusetts Institute of Technology Press, 2011.","apa":"Criminisi, A., Cross, G., Blake, A., & Kolmogorov, V. (2011). Bilayer Segmentation of Video. In A. Blake, P. Kohli, & C. Rother (Eds.), Markov Random Fields for Vision and Image Processing. Massachusetts Institute of Technology Press.","ama":"Criminisi A, Cross G, Blake A, Kolmogorov V. Bilayer Segmentation of Video. In: Blake A, Kohli P, Rother C, eds. Markov Random Fields for Vision and Image Processing. Massachusetts Institute of Technology Press; 2011."},"quality_controlled":0,"date_published":"2011-01-01T00:00:00Z","type":"book_chapter","publist_id":"3813","extern":1,"year":"2011","_id":"2924","status":"public","publication_status":"published","title":"Bilayer Segmentation of Video","editor":[{"first_name":"Andrew","last_name":"Blake","full_name":"Blake, Andrew"},{"full_name":"Kohli, Pushmeet","first_name":"Pushmeet","last_name":"Kohli"},{"full_name":"Rother, Carsten","last_name":"Rother","first_name":"Carsten"}],"publisher":"Massachusetts Institute of Technology Press","author":[{"last_name":"Criminisi","first_name":"Antonio","full_name":"Criminisi, Antonio"},{"first_name":"Geoffrey","last_name":"Cross","full_name":"Cross, Geoffrey"},{"full_name":"Blake, Andrew","first_name":"Andrew","last_name":"Blake"},{"full_name":"Vladimir Kolmogorov","id":"3D50B0BA-F248-11E8-B48F-1D18A9856A87","last_name":"Kolmogorov","first_name":"Vladimir"}],"date_updated":"2021-01-12T07:00:43Z","date_created":"2018-12-11T12:00:22Z"},{"date_updated":"2021-01-12T07:00:44Z","date_created":"2018-12-11T12:00:22Z","author":[{"full_name":"Rother, Carsten","first_name":"Carsten","last_name":"Rother"},{"full_name":"Vladimir Kolmogorov","first_name":"Vladimir","last_name":"Kolmogorov","id":"3D50B0BA-F248-11E8-B48F-1D18A9856A87"},{"full_name":"Boykov, Yuri","first_name":"Yuri","last_name":"Boykov"},{"last_name":"Blake","first_name":"Andrew","full_name":"Blake, Andrew"}],"publisher":"Massachusetts Institute of Technology Press","editor":[{"full_name":"Blake, Andrew","first_name":"Andrew","last_name":"Blake"},{"full_name":"Kohli, Pushmeet","last_name":"Kohli","first_name":"Pushmeet"},{"last_name":"Rother","first_name":"Carsten","full_name":"Rother, Carsten"}],"status":"public","title":"Interactive Foreground Extraction using graph cut","publication_status":"published","year":"2011","_id":"2925","extern":1,"publist_id":"3812","type":"book_chapter","date_published":"2011-01-01T00:00:00Z","quality_controlled":0,"citation":{"mla":"Rother, Carsten, et al. “Interactive Foreground Extraction Using Graph Cut.” Markov Random Fields for Vision and Image Processing, edited by Andrew Blake et al., Massachusetts Institute of Technology Press, 2011.","short":"C. Rother, V. Kolmogorov, Y. Boykov, A. Blake, in:, A. Blake, P. Kohli, C. Rother (Eds.), Markov Random Fields for Vision and Image Processing, Massachusetts Institute of Technology Press, 2011.","chicago":"Rother, Carsten, Vladimir Kolmogorov, Yuri Boykov, and Andrew Blake. “Interactive Foreground Extraction Using Graph Cut.” In Markov Random Fields for Vision and Image Processing, edited by Andrew Blake, Pushmeet Kohli, and Carsten Rother. Massachusetts Institute of Technology Press, 2011.","ama":"Rother C, Kolmogorov V, Boykov Y, Blake A. Interactive Foreground Extraction using graph cut. In: Blake A, Kohli P, Rother C, eds. Markov Random Fields for Vision and Image Processing. Massachusetts Institute of Technology Press; 2011.","ista":"Rother C, Kolmogorov V, Boykov Y, Blake A. 2011.Interactive Foreground Extraction using graph cut. In: Markov Random Fields for Vision and Image Processing. .","ieee":"C. Rother, V. Kolmogorov, Y. Boykov, and A. Blake, “Interactive Foreground Extraction using graph cut,” in Markov Random Fields for Vision and Image Processing, A. Blake, P. Kohli, and C. Rother, Eds. Massachusetts Institute of Technology Press, 2011.","apa":"Rother, C., Kolmogorov, V., Boykov, Y., & Blake, A. (2011). Interactive Foreground Extraction using graph cut. In A. Blake, P. Kohli, & C. Rother (Eds.), Markov Random Fields for Vision and Image Processing. Massachusetts Institute of Technology Press."},"publication":"Markov Random Fields for Vision and Image Processing","month":"01","day":"01"},{"day":"22","month":"07","date_published":"2011-07-22T00:00:00Z","publication":"Markov Random Fields for Vision and Image Processing","citation":{"ista":"Boykov Y, Kolmogorov V. 2011.Basic graph cut algorithms. In: Markov Random Fields for Vision and Image Processing. , 31–50.","ieee":"Y. Boykov and V. Kolmogorov, “Basic graph cut algorithms,” in Markov Random Fields for Vision and Image Processing, A. Blake, P. Kohli, and C. Rother, Eds. Massachusetts Institute of Technology Press, 2011, pp. 31–50.","apa":"Boykov, Y., & Kolmogorov, V. (2011). Basic graph cut algorithms. In A. Blake, P. Kohli, & C. Rother (Eds.), Markov Random Fields for Vision and Image Processing (pp. 31–50). Massachusetts Institute of Technology Press.","ama":"Boykov Y, Kolmogorov V. Basic graph cut algorithms. In: Blake A, Kohli P, Rother C, eds. Markov Random Fields for Vision and Image Processing. Massachusetts Institute of Technology Press; 2011:31-50.","chicago":"Boykov, Yuri, and Vladimir Kolmogorov. “Basic Graph Cut Algorithms.” In Markov Random Fields for Vision and Image Processing, edited by Andrew Blake, Pushmeet Kohli, and Carsten Rother, 31–50. Massachusetts Institute of Technology Press, 2011.","mla":"Boykov, Yuri, and Vladimir Kolmogorov. “Basic Graph Cut Algorithms.” Markov Random Fields for Vision and Image Processing, edited by Andrew Blake et al., Massachusetts Institute of Technology Press, 2011, pp. 31–50.","short":"Y. Boykov, V. Kolmogorov, in:, A. Blake, P. Kohli, C. Rother (Eds.), Markov Random Fields for Vision and Image Processing, Massachusetts Institute of Technology Press, 2011, pp. 31–50."},"quality_controlled":0,"page":"31 - 50","publist_id":"3801","extern":1,"type":"book_chapter","author":[{"full_name":"Boykov, Yuri","first_name":"Yuri","last_name":"Boykov"},{"full_name":"Vladimir Kolmogorov","last_name":"Kolmogorov","first_name":"Vladimir","id":"3D50B0BA-F248-11E8-B48F-1D18A9856A87"}],"date_created":"2018-12-11T12:00:26Z","date_updated":"2021-01-12T07:39:53Z","_id":"2935","year":"2011","status":"public","title":"Basic graph cut algorithms","publication_status":"published","publisher":"Massachusetts Institute of Technology Press","editor":[{"full_name":"Blake, Andrew","last_name":"Blake","first_name":"Andrew"},{"last_name":"Kohli","first_name":"Pushmeet","full_name":"Kohli, Pushmeet"},{"full_name":"Rother, Carsten","first_name":"Carsten","last_name":"Rother"}]},{"date_published":"2011-01-01T00:00:00Z","doi":"http://dx.doi.org/10.18409/jas.v2i1.27","oa":1,"citation":{"ama":"Malaspinas A, Uhler C. Detecting epistasis via Markov bases. Journal of Algebraic Statistics. 2011;2(1):36-53. doi:http://dx.doi.org/10.18409/jas.v2i1.27","ista":"Malaspinas A, Uhler C. 2011. Detecting epistasis via Markov bases. Journal of Algebraic Statistics. 2(1), 36–53.","apa":"Malaspinas, A., & Uhler, C. (2011). Detecting epistasis via Markov bases. Journal of Algebraic Statistics. Public Knowledge Project. http://dx.doi.org/10.18409/jas.v2i1.27","ieee":"A. Malaspinas and C. Uhler, “Detecting epistasis via Markov bases,” Journal of Algebraic Statistics, vol. 2, no. 1. Public Knowledge Project, pp. 36–53, 2011.","mla":"Malaspinas, Anna, and Caroline Uhler. “Detecting Epistasis via Markov Bases.” Journal of Algebraic Statistics, vol. 2, no. 1, Public Knowledge Project, 2011, pp. 36–53, doi:http://dx.doi.org/10.18409/jas.v2i1.27.","short":"A. Malaspinas, C. Uhler, Journal of Algebraic Statistics 2 (2011) 36–53.","chicago":"Malaspinas, Anna, and Caroline Uhler. “Detecting Epistasis via Markov Bases.” Journal of Algebraic Statistics. Public Knowledge Project, 2011. http://dx.doi.org/10.18409/jas.v2i1.27."},"main_file_link":[{"open_access":"1","url":"http://arxiv.org/abs/1006.4929"}],"publication":"Journal of Algebraic Statistics","page":"36 - 53","quality_controlled":0,"day":"01","month":"01","author":[{"full_name":"Malaspinas, Anna-Sapfo ","last_name":"Malaspinas","first_name":"Anna"},{"first_name":"Caroline","last_name":"Uhler","id":"49ADD78E-F248-11E8-B48F-1D18A9856A87","orcid":"0000-0002-7008-0216","full_name":"Caroline Uhler"}],"volume":2,"date_updated":"2021-01-12T07:40:05Z","date_created":"2018-12-11T12:00:34Z","_id":"2961","year":"2011","acknowledgement":"Anna-Sapfo Malaspinas is supported by a Janggen-Poehn Fellowship. Caroline Uhler is supported by an International Fulbright Science and Technology Fellowship.","publisher":"Public Knowledge Project","intvolume":" 2","status":"public","publication_status":"published","title":"Detecting epistasis via Markov bases","publist_id":"3764","issue":"1","abstract":[{"lang":"eng","text":"Rapid research progress in genotyping techniques have allowed large genome-wide association studies. Existing methods often focus on determining associations between single loci and a specic phenotype. However, a particular phenotype is usually the result of complex relationships between multiple loci and the environment. In this paper, we describe a two-stage method for detecting epistasis by combining the traditionally used single-locus search with a search for multiway interactions. Our method is based on an extended version of Fisher's exact test. To\nperform this test, a Markov chain is constructed on the space of multidimensional contingency tables using the elements of a Markov basis as moves. We test our method on simulated data and compare it to a two-stage logistic regression method and to a fully Bayesian method, showing that we are able to detect the interacting loci when other methods fail to do so. Finally, we apply our method to a genome-wide data set consisting of 685 dogs and identify epistasis associated with canine hair length for four pairs of single nucleotide polymorphisms (SNPs)."}],"extern":1,"type":"journal_article"},{"doi":"10.1109/ICDMW.2011.140","date_published":"2011-01-01T00:00:00Z","conference":{"name":"Proceedings of the 11th IEEE International Conference on Data Mining"},"quality_controlled":0,"citation":{"ieee":"S. Fienberg, A. Slavkovic, and C. Uhler, “Privacy Preserving GWAS Data Sharing,” presented at the Proceedings of the 11th IEEE International Conference on Data Mining, 2011.","apa":"Fienberg, S., Slavkovic, A., & Uhler, C. (2011). Privacy Preserving GWAS Data Sharing. Presented at the Proceedings of the 11th IEEE International Conference on Data Mining, IEEE. https://doi.org/10.1109/ICDMW.2011.140","ista":"Fienberg S, Slavkovic A, Uhler C. 2011. Privacy Preserving GWAS Data Sharing. Proceedings of the 11th IEEE International Conference on Data Mining.","ama":"Fienberg S, Slavkovic A, Uhler C. Privacy Preserving GWAS Data Sharing. In: IEEE; 2011. doi:10.1109/ICDMW.2011.140","chicago":"Fienberg, Stephen, Aleksandra Slavkovic, and Caroline Uhler. “Privacy Preserving GWAS Data Sharing.” IEEE, 2011. https://doi.org/10.1109/ICDMW.2011.140.","short":"S. Fienberg, A. Slavkovic, C. Uhler, in:, IEEE, 2011.","mla":"Fienberg, Stephen, et al. Privacy Preserving GWAS Data Sharing. IEEE, 2011, doi:10.1109/ICDMW.2011.140."},"month":"01","day":"01","date_updated":"2021-01-12T07:40:05Z","date_created":"2018-12-11T12:00:34Z","author":[{"last_name":"Fienberg","first_name":"Stephen","full_name":"Fienberg, Stephen E"},{"full_name":"Slavkovic, Aleksandra","first_name":"Aleksandra","last_name":"Slavkovic"},{"full_name":"Caroline Uhler","first_name":"Caroline","last_name":"Uhler","id":"49ADD78E-F248-11E8-B48F-1D18A9856A87","orcid":"0000-0002-7008-0216"}],"publisher":"IEEE","title":"Privacy Preserving GWAS Data Sharing","publication_status":"published","status":"public","_id":"2960","year":"2011","extern":1,"publist_id":"3766","abstract":[{"lang":"eng","text":"Traditional statistical methods for the confidentiality protection for statistical databases do not scale well to deal with GWAS (genome-wide association studies) databases and external information on them. The more recent concept of differential privacy, introduced by the cryptographic community, is an approach which provides a rigorous definition of privacy with meaningful privacy guarantees in the presence of arbitrary external information. Building on such notions, we propose new methods to release aggregate GWAS data without compromising an individual's privacy. We present methods for releasing differentially private minor allele frequencies, chi-square statistics and p-values. We compare these approaches on simulated data and on a GWAS study of canine hair length involving 685 dogs. We also propose a privacy-preserving method for finding genome-wide associations based on a differentially private approach to penalized logistic regression."}],"type":"conference"},{"editor":[{"last_name":"Lee","first_name":"Dong","full_name":"Lee, Dong Hoon"},{"full_name":"Wang, Xiaoyun","first_name":"Xiaoyun","last_name":"Wang"}],"publisher":"Springer","intvolume":" 7073","title":"A Framework for Practical Universally Composable Zero-Knowledge Protocols","publication_status":"published","status":"public","acknowledgement":"This work was in part funded by the Swiss Hasler Foundation, and the EU FP7 grants 216483 and 216499, as well as by the NSF grant CNS-0716690.","_id":"2975","year":"2011","volume":7073,"date_created":"2018-12-11T12:00:39Z","date_updated":"2021-01-12T07:40:11Z","author":[{"full_name":"Camenisch, Jan","first_name":"Jan","last_name":"Camenisch"},{"full_name":"Stephan Krenn","orcid":"0000-0003-2835-9093","id":"329FCCF0-F248-11E8-B48F-1D18A9856A87","last_name":"Krenn","first_name":"Stephan"},{"full_name":"Shoup, Victor","first_name":"Victor","last_name":"Shoup"}],"alternative_title":["LNCS"],"type":"conference","extern":1,"publist_id":"3728","abstract":[{"lang":"eng","text":"Zero-knowledge proofs of knowledge (ZK-PoK) for discrete logarithms and related problems are indispensable for practical cryptographic protocols. Recently, Camenisch, Kiayias, and Yung provided a specification language (the CKY-language) for such protocols which allows for a modular design and protocol analysis: for every zero-knowledge proof specified in this language, protocol designers are ensured that there exists an efficient protocol which indeed proves the specified statement.\n\nHowever, the protocols resulting from their compilation techniques only satisfy the classical notion of ZK-PoK, which is not retained are when they used as building blocks for higher-level applications or composed with other protocols.\nThis problem can be tackled by moving to the Universal Composability (UC) framework, which guarantees retention of security when composing protocols in arbitrary ways. \nWhile there exist generic transformations from $\\Sigma$-protocols to UC-secure protocols, these transformation are often too inefficient for practice.\n \nIn this paper we introduce a specification language akin to the CKY-language and a compiler such that the resulting protocols are UC-secure and efficient. \nTo this end, we propose an extension of the UC-framework addressing the \nissue that UC-secure zero-knowledge proofs are by definition proofs of knowledge, and state a special composition theorem which allows one to use the weaker -- but more efficient and often sufficient -- notion of proofs of membership in the UC-framework. \nWe believe that our contributions enable the design of practically efficient protocols that are UC-secure and thus themselves can be used as building blocks."}],"page":"449 - 467","quality_controlled":0,"citation":{"ama":"Camenisch J, Krenn S, Shoup V. A Framework for Practical Universally Composable Zero-Knowledge Protocols. In: Lee D, Wang X, eds. Vol 7073. Springer; 2011:449-467. doi:10.1007/978-3-642-25385-0","ista":"Camenisch J, Krenn S, Shoup V. 2011. A Framework for Practical Universally Composable Zero-Knowledge Protocols. ASIACRYPT: Theory and Application of Cryptology and Information Security, LNCS, vol. 7073, 449–467.","apa":"Camenisch, J., Krenn, S., & Shoup, V. (2011). A Framework for Practical Universally Composable Zero-Knowledge Protocols. In D. Lee & X. Wang (Eds.) (Vol. 7073, pp. 449–467). Presented at the ASIACRYPT: Theory and Application of Cryptology and Information Security, Springer. https://doi.org/10.1007/978-3-642-25385-0","ieee":"J. Camenisch, S. Krenn, and V. Shoup, “A Framework for Practical Universally Composable Zero-Knowledge Protocols,” presented at the ASIACRYPT: Theory and Application of Cryptology and Information Security, 2011, vol. 7073, pp. 449–467.","mla":"Camenisch, Jan, et al. A Framework for Practical Universally Composable Zero-Knowledge Protocols. Edited by Dong Lee and Xiaoyun Wang, vol. 7073, Springer, 2011, pp. 449–67, doi:10.1007/978-3-642-25385-0.","short":"J. Camenisch, S. Krenn, V. Shoup, in:, D. Lee, X. Wang (Eds.), Springer, 2011, pp. 449–467.","chicago":"Camenisch, Jan, Stephan Krenn, and Victor Shoup. “A Framework for Practical Universally Composable Zero-Knowledge Protocols.” edited by Dong Lee and Xiaoyun Wang, 7073:449–67. Springer, 2011. https://doi.org/10.1007/978-3-642-25385-0."},"main_file_link":[{"url":"http://eprint.iacr.org/2011/228.pdf","open_access":"0"}],"doi":"10.1007/978-3-642-25385-0","date_published":"2011-11-21T00:00:00Z","conference":{"name":"ASIACRYPT: Theory and Application of Cryptology and Information Security"},"month":"11","day":"21"},{"extern":1,"publist_id":"3726","abstract":[{"text":"Cryptographic two-party protocols are used ubiquitously in\n everyday life. While some of these protocols are easy to\n understand and implement (e.g., key exchange or transmission of\n encrypted data), many of them are much more complex (e.g.,\n e-banking and e-voting applications, or anonymous authentication\n and credential systems).\n\n For a software engineer without appropriate cryptographic skills\n the implementation of such protocols is often difficult, time\n consuming and error-prone. For this reason, a number of compilers\n supporting programmers have been published in recent\n years. However, they are either designed for very specific\n cryptographic primitives (e.g., zero-knowledge proofs of\n knowledge), or they only offer a very low level of abstraction and\n thus again demand substantial mathematical and cryptographic\n skills from the programmer. Finally, some of the existing\n compilers do not produce executable code, but only metacode which\n has to be instantiated with mathematical libraries, encryption\n routines, etc. before it can actually be used.\n \n In this paper we present a cryptographically aware compiler which\n is equally useful to cryptographers who want to benchmark\n protocols designed on paper, and to programmers who want to\n implement complex security sensitive protocols without having to\n understand all subtleties. Our tool offers a high level of\n abstraction and outputs well-structured and documented Java\n code. We believe that our compiler can contribute to shortening\n the development cycles of cryptographic applications and to\n reducing their error-proneness.","lang":"eng"}],"type":"conference","date_created":"2018-12-11T12:00:39Z","date_updated":"2021-01-12T07:40:12Z","author":[{"first_name":"Endre","last_name":"Bangerter","full_name":"Bangerter, Endre"},{"full_name":"Stephan Krenn","orcid":"0000-0003-2835-9093","id":"329FCCF0-F248-11E8-B48F-1D18A9856A87","last_name":"Krenn","first_name":"Stephan"},{"first_name":"Martial","last_name":"Seifriz","full_name":"Seifriz, Martial"},{"full_name":"Ultes-Nitsche, Ulrich","last_name":"Ultes Nitsche","first_name":"Ulrich"}],"publisher":"IEEE","editor":[{"full_name":"Venter, Hein S.","first_name":"Hein","last_name":"Venter"},{"full_name":"Coetzee, Marijke","first_name":"Marijke","last_name":"Coetzee"},{"full_name":"Loock, Marianne","first_name":"Marianne","last_name":"Loock"}],"publication_status":"published","title":"cPLC - A Cryptographic Programming Language and Compiler","status":"public","year":"2011","_id":"2977","acknowledgement":"This work was in part funded by the European Community’s Seventh Framework Programme (FP7) under grant agreement no. 216499 and the Swiss Hasler Foundation under projects no. 09037 and 10069.","month":"08","day":"01","doi":"10.1109/ISSA.2011.6027533","date_published":"2011-08-01T00:00:00Z","conference":{"name":"ISSA: Information Security South Africa"},"quality_controlled":0,"citation":{"ama":"Bangerter E, Krenn S, Seifriz M, Ultes Nitsche U. cPLC - A Cryptographic Programming Language and Compiler. In: Venter H, Coetzee M, Loock M, eds. IEEE; 2011. doi:10.1109/ISSA.2011.6027533","ieee":"E. Bangerter, S. Krenn, M. Seifriz, and U. Ultes Nitsche, “cPLC - A Cryptographic Programming Language and Compiler,” presented at the ISSA: Information Security South Africa, 2011.","apa":"Bangerter, E., Krenn, S., Seifriz, M., & Ultes Nitsche, U. (2011). cPLC - A Cryptographic Programming Language and Compiler. In H. Venter, M. Coetzee, & M. Loock (Eds.). Presented at the ISSA: Information Security South Africa, IEEE. https://doi.org/10.1109/ISSA.2011.6027533","ista":"Bangerter E, Krenn S, Seifriz M, Ultes Nitsche U. 2011. cPLC - A Cryptographic Programming Language and Compiler. ISSA: Information Security South Africa.","short":"E. Bangerter, S. Krenn, M. Seifriz, U. Ultes Nitsche, in:, H. Venter, M. Coetzee, M. Loock (Eds.), IEEE, 2011.","mla":"Bangerter, Endre, et al. CPLC - A Cryptographic Programming Language and Compiler. Edited by Hein Venter et al., IEEE, 2011, doi:10.1109/ISSA.2011.6027533.","chicago":"Bangerter, Endre, Stephan Krenn, Martial Seifriz, and Ulrich Ultes Nitsche. “CPLC - A Cryptographic Programming Language and Compiler.” edited by Hein Venter, Marijke Coetzee, and Marianne Loock. IEEE, 2011. https://doi.org/10.1109/ISSA.2011.6027533."}},{"type":"conference","extern":1,"abstract":[{"text":"Side channel attacks on cryptographic systems exploit information\ngained from physical implementations rather than theoretical\nweaknesses of a scheme. In recent years, major achievements were made\nfor the class of so called access-driven cache attacks. Such attacks\nexploit the leakage of the memory locations accessed by a victim\nprocess.\n\nIn this paper we consider the AES block cipher and present an attack\nwhich is capable of recovering the full secret key in almost realtime\nfor AES-128, requiring only a very limited number of observed\nencryptions. Unlike previous attacks, we do not require any\ninformation about the plaintext (such as its distribution, etc.).\nMoreover, for the first time, we also show how the plaintext can be\nrecovered without having access to the ciphertext at all. It is the\nfirst working attack on AES implementations using compressed\ntables. There, no efficient techniques to identify the beginning\nof AES rounds is known, which is the fundamental assumption underlying previous\nattacks.\n\nWe have a fully working implementation of our attack which is able to\nrecover AES keys after observing as little as 100 encryptions. It\nworks against the OpenSSL 0.9.8n implementation of AES on Linux\nsystems. Our spy process does not require any special privileges\nbeyond those of a standard Linux user. A contribution of probably\nindependent interest is a denial of service attack on the task scheduler of\ncurrent Linux systems (CFS), which allows one to observe (on average)\nevery single memory access of a victim process.","lang":"eng"}],"publist_id":"3727","status":"public","publication_status":"published","title":"Cache Games - Bringing Access-Based Cache Attacks on AES to Practice","publisher":"IEEE","year":"2011","_id":"2976","acknowledgement":"This work was in part funded by the European Community’s Seventh Framework Programme (FP7) under grant agreement no. 216499 and the Swiss Hasler Foundation.\nAn extended abstract was also accepted for COSADE 2011.","date_created":"2018-12-11T12:00:39Z","date_updated":"2021-01-12T07:40:11Z","author":[{"last_name":"Gullasch","first_name":"David","full_name":"Gullasch, David"},{"last_name":"Bangerter","first_name":"Endre","full_name":"Bangerter, Endre"},{"full_name":"Stephan Krenn","id":"329FCCF0-F248-11E8-B48F-1D18A9856A87","orcid":"0000-0003-2835-9093","first_name":"Stephan","last_name":"Krenn"}],"month":"01","day":"01","quality_controlled":0,"page":"490 - 505","citation":{"ista":"Gullasch D, Bangerter E, Krenn S. 2011. Cache Games - Bringing Access-Based Cache Attacks on AES to Practice. S&P: IEEE Symposium on Security and Privacy, 490–505.","ieee":"D. Gullasch, E. Bangerter, and S. Krenn, “Cache Games - Bringing Access-Based Cache Attacks on AES to Practice,” presented at the S&P: IEEE Symposium on Security and Privacy, 2011, pp. 490–505.","apa":"Gullasch, D., Bangerter, E., & Krenn, S. (2011). Cache Games - Bringing Access-Based Cache Attacks on AES to Practice (pp. 490–505). Presented at the S&P: IEEE Symposium on Security and Privacy, IEEE. https://doi.org/10.1109/SP.2011.22","ama":"Gullasch D, Bangerter E, Krenn S. Cache Games - Bringing Access-Based Cache Attacks on AES to Practice. In: IEEE; 2011:490-505. doi:10.1109/SP.2011.22","chicago":"Gullasch, David, Endre Bangerter, and Stephan Krenn. “Cache Games - Bringing Access-Based Cache Attacks on AES to Practice,” 490–505. IEEE, 2011. https://doi.org/10.1109/SP.2011.22.","mla":"Gullasch, David, et al. Cache Games - Bringing Access-Based Cache Attacks on AES to Practice. IEEE, 2011, pp. 490–505, doi:10.1109/SP.2011.22.","short":"D. Gullasch, E. Bangerter, S. Krenn, in:, IEEE, 2011, pp. 490–505."},"main_file_link":[{"url":"http://eprint.iacr.org/2010/594.pdf","open_access":"0"}],"conference":{"name":"S&P: IEEE Symposium on Security and Privacy"},"date_published":"2011-01-01T00:00:00Z","doi":"10.1109/SP.2011.22"},{"quality_controlled":"1","main_file_link":[{"url":"https://www.ncbi.nlm.nih.gov/pubmed/21660355","open_access":"1"}],"oa":1,"external_id":{"pmid":["21660355"]},"language":[{"iso":"eng"}],"doi":"10.1039/c1mb05109a","month":"06","publication_status":"published","publisher":"Royal Society of Chemistry","year":"2011","pmid":1,"date_updated":"2021-01-12T07:41:00Z","date_created":"2018-12-11T12:01:20Z","volume":7,"author":[{"full_name":"Wabnik, Krzysztof T","orcid":"0000-0001-7263-0560","id":"4DE369A4-F248-11E8-B48F-1D18A9856A87","last_name":"Wabnik","first_name":"Krzysztof T"},{"full_name":"Govaerts, Willy","first_name":"Willy","last_name":"Govaerts"},{"full_name":"Friml, Jirí","orcid":"0000-0002-8302-7596","id":"4159519E-F248-11E8-B48F-1D18A9856A87","last_name":"Friml","first_name":"Jirí"},{"first_name":"Jürgen","last_name":"Kleine Vehn","full_name":"Kleine Vehn, Jürgen"}],"extern":"1","publist_id":"3608","page":"2352 - 2359","publication":"Molecular BioSystems","citation":{"chicago":"Wabnik, Krzysztof T, Willy Govaerts, Jiří Friml, and Jürgen Kleine Vehn. “Feedback Models for Polarized Auxin Transport: An Emerging Trend.” Molecular BioSystems. Royal Society of Chemistry, 2011. https://doi.org/10.1039/c1mb05109a.","mla":"Wabnik, Krzysztof T., et al. “Feedback Models for Polarized Auxin Transport: An Emerging Trend.” Molecular BioSystems, vol. 7, no. 8, Royal Society of Chemistry, 2011, pp. 2352–59, doi:10.1039/c1mb05109a.","short":"K.T. Wabnik, W. Govaerts, J. Friml, J. Kleine Vehn, Molecular BioSystems 7 (2011) 2352–2359.","ista":"Wabnik KT, Govaerts W, Friml J, Kleine Vehn J. 2011. Feedback models for polarized auxin transport: An emerging trend. Molecular BioSystems. 7(8), 2352–2359.","ieee":"K. T. Wabnik, W. Govaerts, J. Friml, and J. Kleine Vehn, “Feedback models for polarized auxin transport: An emerging trend,” Molecular BioSystems, vol. 7, no. 8. Royal Society of Chemistry, pp. 2352–2359, 2011.","apa":"Wabnik, K. T., Govaerts, W., Friml, J., & Kleine Vehn, J. (2011). Feedback models for polarized auxin transport: An emerging trend. Molecular BioSystems. Royal Society of Chemistry. https://doi.org/10.1039/c1mb05109a","ama":"Wabnik KT, Govaerts W, Friml J, Kleine Vehn J. Feedback models for polarized auxin transport: An emerging trend. Molecular BioSystems. 2011;7(8):2352-2359. doi:10.1039/c1mb05109a"},"date_published":"2011-06-10T00:00:00Z","day":"10","title":"Feedback models for polarized auxin transport: An emerging trend","status":"public","intvolume":" 7","user_id":"3E5EF7F0-F248-11E8-B48F-1D18A9856A87","_id":"3092","oa_version":"Published Version","type":"journal_article","abstract":[{"lang":"eng","text":"The phytohormone auxin is vital to plant growth and development. A unique property of auxin among all other plant hormones is its cell-to-cell polar transport that requires activity of polarly localized PIN-FORMED (PIN) auxin efflux transporters. Despite the substantial molecular insight into the cellular PIN polarization, the mechanistic understanding for developmentally and environmentally regulated PIN polarization is scarce. The long-standing belief that auxin modulates its own transport by means of a positive feedback mechanism has inspired both experimentalists and theoreticians for more than two decades. Recently, theoretical models for auxin-dependent patterning in plants include the feedback between auxin transport and the PIN protein localization. These computer models aid to assess the complexity of plant development by testing and predicting plausible scenarios for various developmental processes that occur in planta. Although the majority of these models rely on purely heuristic principles, the most recent mechanistic models tentatively integrate biologically testable components into known cellular processes that underlie the PIN polarity regulation. The existing and emerging computational approaches to describe PIN polarization are presented and discussed in the light of recent experimental data on the PIN polar targeting."}],"issue":"8"},{"day":"14","month":"06","quality_controlled":0,"page":"855 - 866","publication":"Developmental Cell","citation":{"mla":"Zhang, Jing, et al. “Inositol Trisphosphate-Induced Ca^2+ Signaling Modulates Auxin Transport and Pin Polarity.” Developmental Cell, vol. 20, no. 6, Cell Press, 2011, pp. 855–66, doi:10.1016/j.devcel.2011.05.013.","short":"J. Zhang, S. Vanneste, P. Brewer, M. Michniewicz, P. Grones, J. Kleine Vehn, C. Löfke, T. Teichmann, A. Bielach, B. Cannoot, K. Hoyerová, X. Chen, H. Xue, E. Benková, E. Zažímalová, J. Friml, Developmental Cell 20 (2011) 855–866.","chicago":"Zhang, Jing, Steffen Vanneste, Philip Brewer, Marta Michniewicz, Peter Grones, Jürgen Kleine Vehn, Christian Löfke, et al. “Inositol Trisphosphate-Induced Ca^2+ Signaling Modulates Auxin Transport and Pin Polarity.” Developmental Cell. Cell Press, 2011. https://doi.org/10.1016/j.devcel.2011.05.013.","ama":"Zhang J, Vanneste S, Brewer P, et al. Inositol trisphosphate-induced ca^2+ signaling modulates auxin transport and pin polarity. Developmental Cell. 2011;20(6):855-866. doi:10.1016/j.devcel.2011.05.013","ista":"Zhang J, Vanneste S, Brewer P, Michniewicz M, Grones P, Kleine Vehn J, Löfke C, Teichmann T, Bielach A, Cannoot B, Hoyerová K, Chen X, Xue H, Benková E, Zažímalová E, Friml J. 2011. Inositol trisphosphate-induced ca^2+ signaling modulates auxin transport and pin polarity. Developmental Cell. 20(6), 855–866.","apa":"Zhang, J., Vanneste, S., Brewer, P., Michniewicz, M., Grones, P., Kleine Vehn, J., … Friml, J. (2011). Inositol trisphosphate-induced ca^2+ signaling modulates auxin transport and pin polarity. Developmental Cell. Cell Press. https://doi.org/10.1016/j.devcel.2011.05.013","ieee":"J. Zhang et al., “Inositol trisphosphate-induced ca^2+ signaling modulates auxin transport and pin polarity,” Developmental Cell, vol. 20, no. 6. Cell Press, pp. 855–866, 2011."},"doi":"10.1016/j.devcel.2011.05.013","date_published":"2011-06-14T00:00:00Z","type":"journal_article","extern":1,"abstract":[{"lang":"eng","text":"The phytohormone auxin is an important determinant of plant development. Directional auxin flow within tissues depends on polar localization of PIN auxin transporters. To explore regulation of PIN-mediated auxin transport, we screened for suppressors of PIN1 overexpression (supo) and identified an inositol polyphosphate 1-phosphatase mutant (supo1), with elevated inositol trisphosphate (InsP 3) and cytosolic Ca 2+ levels. Pharmacological and genetic increases in InsP 3 or Ca 2+ levels also suppressed the PIN1 gain-of-function phenotypes and caused defects in basal PIN localization, auxin transport and auxin-mediated development. In contrast, the reductions in InsP 3 levels and Ca 2+ signaling antagonized the effects of the supo1 mutation and disrupted preferentially apical PIN localization. InsP 3 and Ca 2+ are evolutionarily conserved second messengers involved in various cellular functions, particularly stress responses. Our findings implicate them as modifiers of cell polarity and polar auxin transport, and highlight a potential integration point through which Ca 2+ signaling-related stimuli could influence auxin-mediated development."}],"publist_id":"3612","issue":"6","status":"public","title":"Inositol trisphosphate-induced ca^2+ signaling modulates auxin transport and pin polarity","publication_status":"published","intvolume":" 20","publisher":"Cell Press","_id":"3089","year":"2011","date_updated":"2021-01-12T07:40:58Z","date_created":"2018-12-11T12:01:18Z","volume":20,"author":[{"full_name":"Zhang, Jing","last_name":"Zhang","first_name":"Jing"},{"full_name":"Vanneste, Steffen","last_name":"Vanneste","first_name":"Steffen"},{"full_name":"Brewer, Philip B","last_name":"Brewer","first_name":"Philip"},{"full_name":"Michniewicz, Marta","first_name":"Marta","last_name":"Michniewicz"},{"full_name":"Peter Grones","id":"399876EC-F248-11E8-B48F-1D18A9856A87","last_name":"Grones","first_name":"Peter"},{"full_name":"Kleine-Vehn, Jürgen","last_name":"Kleine Vehn","first_name":"Jürgen"},{"last_name":"Löfke","first_name":"Christian","full_name":"Löfke, Christian"},{"full_name":"Teichmann, Thomas","first_name":"Thomas","last_name":"Teichmann"},{"full_name":"Bielach, Agnieszka","last_name":"Bielach","first_name":"Agnieszka"},{"full_name":"Cannoot, Bernard","first_name":"Bernard","last_name":"Cannoot"},{"first_name":"Klára","last_name":"Hoyerová","full_name":"Hoyerová, Klára"},{"full_name":"Xu Chen","first_name":"Xu","last_name":"Chen","id":"4E5ADCAA-F248-11E8-B48F-1D18A9856A87"},{"full_name":"Xue, Hong-Wei","first_name":"Hong","last_name":"Xue"},{"first_name":"Eva","last_name":"Benková","id":"38F4F166-F248-11E8-B48F-1D18A9856A87","orcid":"0000-0002-8510-9739","full_name":"Eva Benková"},{"last_name":"Zažímalová","first_name":"Eva","full_name":"Zažímalová, Eva"},{"full_name":"Jirí Friml","last_name":"Friml","first_name":"Jirí","orcid":"0000-0002-8302-7596","id":"4159519E-F248-11E8-B48F-1D18A9856A87"}]},{"type":"journal_article","publist_id":"3611","issue":"12","abstract":[{"lang":"eng","text":"The polarized transport of the phytohormone auxin [1], which is crucial for the regulation of different stages of plant development [2, 3], depends on the asymmetric plasma membrane distribution of the PIN-FORMED (PIN) auxin efflux carriers [4, 5]. The PIN polar localization results from clathrin-mediated endocytosis (CME) from the plasma membrane and subsequent polar recycling [6]. The Arabidopsis genome encodes two groups of dynamin-related proteins (DRPs) that show homology to mammalian dynamin - a protein required for fission of endocytic vesicles during CME [7, 8]. Here we show by coimmunoprecipitation (coIP), bimolecular fluorescence complementation (BiFC), and Förster resonance energy transfer (FRET) that members of the DRP1 group closely associate with PIN proteins at the cell plate. Localization and phenotypic analysis of novel drp1 mutants revealed a requirement for DRP1 function in correct PIN distribution and in auxin-mediated development. We propose that rapid and specific internalization of PIN proteins mediated by the DRP1 proteins and the associated CME machinery from the cell plate membranes during cytokinesis is an important mechanism for proper polar PIN positioning in interphase cells."}],"extern":1,"_id":"3090","year":"2011","publisher":"Cell Press","intvolume":" 21","title":"Cell plate restricted association of DRP1A and PIN proteins is required for cell polarity establishment in arabidopsis","publication_status":"published","status":"public","author":[{"last_name":"Mravec","first_name":"Jozef","full_name":"Mravec, Jozef"},{"full_name":"Petrášek, Jan","last_name":"Petrášek","first_name":"Jan"},{"full_name":"Li, Na","last_name":"Li","first_name":"Na"},{"full_name":"Boeren, Sjef","first_name":"Sjef","last_name":"Boeren"},{"last_name":"Karlova","first_name":"Rumyana","full_name":"Karlova, Rumyana"},{"first_name":"Saeko","last_name":"Kitakura","full_name":"Kitakura, Saeko"},{"full_name":"Pařezová, Markéta","first_name":"Markéta","last_name":"Pařezová"},{"full_name":"Naramoto, Satoshi","last_name":"Naramoto","first_name":"Satoshi"},{"first_name":"Thomasz","last_name":"Nodzyński","full_name":"Nodzyński, Thomasz"},{"full_name":"Dhonukshe, Pankaj","first_name":"Pankaj","last_name":"Dhonukshe"},{"first_name":"Sebastian","last_name":"Bednarek","full_name":"Bednarek, Sebastian Y"},{"full_name":"Zažímalová, Eva","last_name":"Zažímalová","first_name":"Eva"},{"full_name":"De Vries, Sacco","first_name":"Sacco","last_name":"De Vries"},{"full_name":"Jirí Friml","id":"4159519E-F248-11E8-B48F-1D18A9856A87","orcid":"0000-0002-8302-7596","first_name":"Jirí","last_name":"Friml"}],"volume":21,"date_updated":"2021-01-12T07:40:59Z","date_created":"2018-12-11T12:01:19Z","month":"06","day":"21","citation":{"ista":"Mravec J, Petrášek J, Li N, Boeren S, Karlova R, Kitakura S, Pařezová M, Naramoto S, Nodzyński T, Dhonukshe P, Bednarek S, Zažímalová E, De Vries S, Friml J. 2011. Cell plate restricted association of DRP1A and PIN proteins is required for cell polarity establishment in arabidopsis. Current Biology. 21(12), 1055–1060.","ieee":"J. Mravec et al., “Cell plate restricted association of DRP1A and PIN proteins is required for cell polarity establishment in arabidopsis,” Current Biology, vol. 21, no. 12. Cell Press, pp. 1055–1060, 2011.","apa":"Mravec, J., Petrášek, J., Li, N., Boeren, S., Karlova, R., Kitakura, S., … Friml, J. (2011). Cell plate restricted association of DRP1A and PIN proteins is required for cell polarity establishment in arabidopsis. Current Biology. Cell Press. https://doi.org/10.1016/j.cub.2011.05.018","ama":"Mravec J, Petrášek J, Li N, et al. Cell plate restricted association of DRP1A and PIN proteins is required for cell polarity establishment in arabidopsis. Current Biology. 2011;21(12):1055-1060. doi:10.1016/j.cub.2011.05.018","chicago":"Mravec, Jozef, Jan Petrášek, Na Li, Sjef Boeren, Rumyana Karlova, Saeko Kitakura, Markéta Pařezová, et al. “Cell Plate Restricted Association of DRP1A and PIN Proteins Is Required for Cell Polarity Establishment in Arabidopsis.” Current Biology. Cell Press, 2011. https://doi.org/10.1016/j.cub.2011.05.018.","mla":"Mravec, Jozef, et al. “Cell Plate Restricted Association of DRP1A and PIN Proteins Is Required for Cell Polarity Establishment in Arabidopsis.” Current Biology, vol. 21, no. 12, Cell Press, 2011, pp. 1055–60, doi:10.1016/j.cub.2011.05.018.","short":"J. Mravec, J. Petrášek, N. Li, S. Boeren, R. Karlova, S. Kitakura, M. Pařezová, S. Naramoto, T. Nodzyński, P. Dhonukshe, S. Bednarek, E. Zažímalová, S. De Vries, J. Friml, Current Biology 21 (2011) 1055–1060."},"publication":"Current Biology","page":"1055 - 1060","quality_controlled":0,"date_published":"2011-06-21T00:00:00Z","doi":"10.1016/j.cub.2011.05.018"},{"quality_controlled":0,"page":"917 - 926","publication":"Current Biology","citation":{"ista":"Bishopp A, Help H, El Showk S, Weijers D, Scheres B, Friml J, Benková E, Mähönen A, Helariutta Y. 2011. A mutually inhibitory interaction between auxin and cytokinin specifies vascular pattern in roots. Current Biology. 21(11), 917–926.","apa":"Bishopp, A., Help, H., El Showk, S., Weijers, D., Scheres, B., Friml, J., … Helariutta, Y. (2011). A mutually inhibitory interaction between auxin and cytokinin specifies vascular pattern in roots. Current Biology. Cell Press. https://doi.org/10.1016/j.cub.2011.04.017","ieee":"A. Bishopp et al., “A mutually inhibitory interaction between auxin and cytokinin specifies vascular pattern in roots,” Current Biology, vol. 21, no. 11. Cell Press, pp. 917–926, 2011.","ama":"Bishopp A, Help H, El Showk S, et al. A mutually inhibitory interaction between auxin and cytokinin specifies vascular pattern in roots. Current Biology. 2011;21(11):917-926. doi:10.1016/j.cub.2011.04.017","chicago":"Bishopp, Anthony, Hanna Help, Sedeer El Showk, Dolf Weijers, Ben Scheres, Jiří Friml, Eva Benková, Ari Mähönen, and Ykä Helariutta. “A Mutually Inhibitory Interaction between Auxin and Cytokinin Specifies Vascular Pattern in Roots.” Current Biology. Cell Press, 2011. https://doi.org/10.1016/j.cub.2011.04.017.","mla":"Bishopp, Anthony, et al. “A Mutually Inhibitory Interaction between Auxin and Cytokinin Specifies Vascular Pattern in Roots.” Current Biology, vol. 21, no. 11, Cell Press, 2011, pp. 917–26, doi:10.1016/j.cub.2011.04.017.","short":"A. Bishopp, H. Help, S. El Showk, D. Weijers, B. Scheres, J. Friml, E. Benková, A. Mähönen, Y. Helariutta, Current Biology 21 (2011) 917–926."},"date_published":"2011-06-07T00:00:00Z","doi":"10.1016/j.cub.2011.04.017","day":"07","month":"06","title":"A mutually inhibitory interaction between auxin and cytokinin specifies vascular pattern in roots","publication_status":"published","status":"public","intvolume":" 21","publisher":"Cell Press","_id":"3088","year":"2011","date_updated":"2021-01-12T07:40:58Z","date_created":"2018-12-11T12:01:18Z","volume":21,"author":[{"first_name":"Anthony","last_name":"Bishopp","full_name":"Bishopp, Anthony"},{"full_name":"Help, Hanna","last_name":"Help","first_name":"Hanna"},{"full_name":"El-Showk, Sedeer","first_name":"Sedeer","last_name":"El Showk"},{"full_name":"Weijers, Dolf","first_name":"Dolf","last_name":"Weijers"},{"full_name":"Scheres, Ben","last_name":"Scheres","first_name":"Ben"},{"id":"4159519E-F248-11E8-B48F-1D18A9856A87","orcid":"0000-0002-8302-7596","first_name":"Jirí","last_name":"Friml","full_name":"Jirí Friml"},{"orcid":"0000-0002-8510-9739","id":"38F4F166-F248-11E8-B48F-1D18A9856A87","last_name":"Benková","first_name":"Eva","full_name":"Eva Benková"},{"last_name":"Mähönen","first_name":"Ari","full_name":"Mähönen, Ari Pekka"},{"full_name":"Helariutta, Ykä","last_name":"Helariutta","first_name":"Ykä"}],"type":"journal_article","extern":1,"abstract":[{"text":"Background: Whereas the majority of animals develop toward a predetermined body plan, plants show iterative growth and continually produce new organs and structures from actively dividing meristems. This raises an intriguing question: How are these newly developed organs patterned? In Arabidopsis embryos, radial symmetry is broken by the bisymmetric specification of the cotyledons in the apical domain. Subsequently, this bisymmetry is propagated to the root promeristem. Results: Here we present a mutually inhibitory feedback loop between auxin and cytokinin that sets distinct boundaries of hormonal output. Cytokinins promote the bisymmetric distribution of the PIN-FORMED (PIN) auxin efflux proteins, which channel auxin toward a central domain. High auxin promotes transcription of the cytokinin signaling inhibitor AHP6, which closes the interaction loop. This bisymmetric auxin response domain specifies the differentiation of protoxylem in a bisymmetric pattern. In embryonic roots, cytokinin is required to translate a bisymmetric auxin response in the cotyledons to a bisymmetric vascular pattern in the root promeristem. Conclusions: Our results present an interactive feedback loop between hormonal signaling and transport by which small biases in hormonal input are propagated into distinct signaling domains to specify the vascular pattern in the root meristem. It is an intriguing possibility that such a mechanism could transform radial patterns and allow continuous vascular connections between other newly emerging organs.","lang":"eng"}],"issue":"11","publist_id":"3613"},{"intvolume":" 108","publisher":"National Academy of Sciences","status":"public","publication_status":"published","title":"Monoubiquitin dependent endocytosis of the Iron Regulated Transporter 1 IRT1 transporter controls iron uptake in plants","_id":"3093","year":"2011","volume":108,"date_updated":"2021-01-12T07:41:00Z","date_created":"2018-12-11T12:01:20Z","author":[{"first_name":"Marie","last_name":"Barberon","full_name":"Barberon, Marie"},{"last_name":"Zelazny","first_name":"Enric","full_name":"Zelazny, Enric"},{"first_name":"Stéphanie","last_name":"Robert","full_name":"Robert, Stéphanie"},{"last_name":"Conéjéro","first_name":"Geneviève","full_name":"Conéjéro, Geneviève"},{"last_name":"Curie","first_name":"Cathy","full_name":"Curie, Cathy"},{"first_name":"Jirí","last_name":"Friml","id":"4159519E-F248-11E8-B48F-1D18A9856A87","orcid":"0000-0002-8302-7596","full_name":"Jirí Friml"},{"first_name":"Grégory","last_name":"Vert","full_name":"Vert, Grégory"}],"type":"journal_article","extern":1,"publist_id":"3607","issue":"32","abstract":[{"lang":"eng","text":"\nPlants take up iron from the soil using the IRON-REGULATED TRANSPORTER 1 (IRT1) high-affinity iron transporter at the root surface. Sophisticated regulatory mechanisms allow plants to tightly control the levels of IRT1, ensuring optimal absorption of essential but toxic iron. Here, we demonstrate that overexpression of Arabidopsis thaliana IRT1 leads to constitutive IRT1 protein accumulation, metal overload, and oxidative stress. IRT1 is unexpectedly found in trans-Golgi network/early endosomes of root hair cells, and its levels and localization are unaffected by iron nutrition. Using pharmacological approaches, we show that IRT1 cycles to the plasma membrane to perform iron and metal uptake at the cell surface and is sent to the vacuole for proper turnover. We also prove that IRT1 is monoubiquitinated on several cytosol-exposed residues in vivo and that mutation of two putative monoubiquitination target residues in IRT1 triggers stabilization at the plasma membrane and leads to extreme lethality. Together, these data suggest a model in which monoubiquitin-dependent internalization/sorting and turnover keep the plasma membrane pool of IRT1 low to ensure proper iron uptake and to prevent metal toxicity. More generally, our work demonstrates the existence of monoubiquitin-dependent trafficking to lytic vacuoles in plants and points to proteasome-independent turnover of plasma membrane proteins."}],"page":"E450 - E458","quality_controlled":0,"citation":{"ama":"Barberon M, Zelazny E, Robert S, et al. Monoubiquitin dependent endocytosis of the Iron Regulated Transporter 1 IRT1 transporter controls iron uptake in plants. PNAS. 2011;108(32):E450-E458. doi:10.1073/pnas.1100659108","apa":"Barberon, M., Zelazny, E., Robert, S., Conéjéro, G., Curie, C., Friml, J., & Vert, G. (2011). Monoubiquitin dependent endocytosis of the Iron Regulated Transporter 1 IRT1 transporter controls iron uptake in plants. PNAS. National Academy of Sciences. https://doi.org/10.1073/pnas.1100659108","ieee":"M. Barberon et al., “Monoubiquitin dependent endocytosis of the Iron Regulated Transporter 1 IRT1 transporter controls iron uptake in plants,” PNAS, vol. 108, no. 32. National Academy of Sciences, pp. E450–E458, 2011.","ista":"Barberon M, Zelazny E, Robert S, Conéjéro G, Curie C, Friml J, Vert G. 2011. Monoubiquitin dependent endocytosis of the Iron Regulated Transporter 1 IRT1 transporter controls iron uptake in plants. PNAS. 108(32), E450–E458.","short":"M. Barberon, E. Zelazny, S. Robert, G. Conéjéro, C. Curie, J. Friml, G. Vert, PNAS 108 (2011) E450–E458.","mla":"Barberon, Marie, et al. “Monoubiquitin Dependent Endocytosis of the Iron Regulated Transporter 1 IRT1 Transporter Controls Iron Uptake in Plants.” PNAS, vol. 108, no. 32, National Academy of Sciences, 2011, pp. E450–58, doi:10.1073/pnas.1100659108.","chicago":"Barberon, Marie, Enric Zelazny, Stéphanie Robert, Geneviève Conéjéro, Cathy Curie, Jiří Friml, and Grégory Vert. “Monoubiquitin Dependent Endocytosis of the Iron Regulated Transporter 1 IRT1 Transporter Controls Iron Uptake in Plants.” PNAS. National Academy of Sciences, 2011. https://doi.org/10.1073/pnas.1100659108."},"publication":"PNAS","date_published":"2011-08-09T00:00:00Z","doi":"10.1073/pnas.1100659108","month":"08","day":"09"},{"type":"journal_article","issue":"5","publist_id":"3606","abstract":[{"text":"Summary Gravitropism aligns plant growth with gravity. It involves gravity perception and the asymmetric distribution of the phytohormone auxin. Here we provide insights into the mechanism for hypocotyl gravitropic growth. We show that the Arabidopsis thaliana PIN3 auxin transporter is required for the asymmetric auxin distribution for the gravitropic response. Gravistimulation polarizes PIN3 to the bottom side of hypocotyl endodermal cells, which correlates with an increased auxin response at the lower hypocotyl side. Both PIN3 polarization and hypocotyl bending require the activity of the trafficking regulator GNOM and the protein kinase PINOID. Our data suggest that gravity-induced PIN3 polarization diverts the auxin flow to mediate the asymmetric distribution of auxin for gravitropic shoot bending.","lang":"eng"}],"extern":1,"_id":"3094","year":"2011","intvolume":" 67","publisher":"Wiley-Blackwell","publication_status":"published","title":"Polarization of PIN3 dependent auxin transport for hypocotyl gravitropic response in Arabidopsis thaliana","status":"public","author":[{"first_name":"Hana","last_name":"Rakusová","full_name":"Rakusová, Hana"},{"last_name":"Gallego Bartolomé","first_name":"Javier","full_name":"Gallego-Bartolomé, Javier"},{"full_name":"Vanstraelen, Marleen","last_name":"Vanstraelen","first_name":"Marleen"},{"first_name":"Hélène","last_name":"Robert","full_name":"Robert, Hélène S"},{"last_name":"Alabadí","first_name":"David","full_name":"Alabadí, David"},{"full_name":"Blázquez, Miguel A","first_name":"Miguel","last_name":"Blázquez"},{"full_name":"Eva Benková","orcid":"0000-0002-8510-9739","id":"38F4F166-F248-11E8-B48F-1D18A9856A87","last_name":"Benková","first_name":"Eva"},{"last_name":"Friml","first_name":"Jirí","orcid":"0000-0002-8302-7596","id":"4159519E-F248-11E8-B48F-1D18A9856A87","full_name":"Jirí Friml"}],"volume":67,"date_created":"2018-12-11T12:01:21Z","date_updated":"2021-01-12T07:41:01Z","day":"01","month":"09","citation":{"ama":"Rakusová H, Gallego Bartolomé J, Vanstraelen M, et al. Polarization of PIN3 dependent auxin transport for hypocotyl gravitropic response in Arabidopsis thaliana. Plant Journal. 2011;67(5):817-826. doi:10.1111/j.1365-313X.2011.04636.x","ista":"Rakusová H, Gallego Bartolomé J, Vanstraelen M, Robert H, Alabadí D, Blázquez M, Benková E, Friml J. 2011. Polarization of PIN3 dependent auxin transport for hypocotyl gravitropic response in Arabidopsis thaliana. Plant Journal. 67(5), 817–826.","ieee":"H. Rakusová et al., “Polarization of PIN3 dependent auxin transport for hypocotyl gravitropic response in Arabidopsis thaliana,” Plant Journal, vol. 67, no. 5. Wiley-Blackwell, pp. 817–826, 2011.","apa":"Rakusová, H., Gallego Bartolomé, J., Vanstraelen, M., Robert, H., Alabadí, D., Blázquez, M., … Friml, J. (2011). Polarization of PIN3 dependent auxin transport for hypocotyl gravitropic response in Arabidopsis thaliana. Plant Journal. Wiley-Blackwell. https://doi.org/10.1111/j.1365-313X.2011.04636.x","mla":"Rakusová, Hana, et al. “Polarization of PIN3 Dependent Auxin Transport for Hypocotyl Gravitropic Response in Arabidopsis Thaliana.” Plant Journal, vol. 67, no. 5, Wiley-Blackwell, 2011, pp. 817–26, doi:10.1111/j.1365-313X.2011.04636.x.","short":"H. Rakusová, J. Gallego Bartolomé, M. Vanstraelen, H. Robert, D. Alabadí, M. Blázquez, E. Benková, J. Friml, Plant Journal 67 (2011) 817–826.","chicago":"Rakusová, Hana, Javier Gallego Bartolomé, Marleen Vanstraelen, Hélène Robert, David Alabadí, Miguel Blázquez, Eva Benková, and Jiří Friml. “Polarization of PIN3 Dependent Auxin Transport for Hypocotyl Gravitropic Response in Arabidopsis Thaliana.” Plant Journal. Wiley-Blackwell, 2011. https://doi.org/10.1111/j.1365-313X.2011.04636.x."},"publication":"Plant Journal","page":"817 - 826","quality_controlled":0,"doi":"10.1111/j.1365-313X.2011.04636.x","date_published":"2011-09-01T00:00:00Z"},{"author":[{"full_name":"Sauer, Michael","first_name":"Michael","last_name":"Sauer"},{"full_name":"Friml, Jirí","orcid":"0000-0002-8302-7596","id":"4159519E-F248-11E8-B48F-1D18A9856A87","last_name":"Friml","first_name":"Jirí"}],"date_created":"2018-12-11T12:01:19Z","date_updated":"2021-01-12T07:41:00Z","volume":7,"oa_version":"Published Version","_id":"3091","year":"2011","user_id":"3E5EF7F0-F248-11E8-B48F-1D18A9856A87","pmid":1,"publication_status":"published","status":"public","title":"Fleeting hormone cues get stabilized for plant organogenesis","publisher":"Nature Publishing Group","intvolume":" 7","publist_id":"3610","extern":"1","type":"journal_article","doi":"10.1038/msb.2011.45","date_published":"2011-07-05T00:00:00Z","language":[{"iso":"eng"}],"publication":"Molecular Systems Biology","citation":{"ama":"Sauer M, Friml J. Fleeting hormone cues get stabilized for plant organogenesis. Molecular Systems Biology. 2011;7. doi:10.1038/msb.2011.45","ista":"Sauer M, Friml J. 2011. Fleeting hormone cues get stabilized for plant organogenesis. Molecular Systems Biology. 7.","ieee":"M. Sauer and J. Friml, “Fleeting hormone cues get stabilized for plant organogenesis,” Molecular Systems Biology, vol. 7. Nature Publishing Group, 2011.","apa":"Sauer, M., & Friml, J. (2011). Fleeting hormone cues get stabilized for plant organogenesis. Molecular Systems Biology. Nature Publishing Group. https://doi.org/10.1038/msb.2011.45","mla":"Sauer, Michael, and Jiří Friml. “Fleeting Hormone Cues Get Stabilized for Plant Organogenesis.” Molecular Systems Biology, vol. 7, Nature Publishing Group, 2011, doi:10.1038/msb.2011.45.","short":"M. Sauer, J. Friml, Molecular Systems Biology 7 (2011).","chicago":"Sauer, Michael, and Jiří Friml. “Fleeting Hormone Cues Get Stabilized for Plant Organogenesis.” Molecular Systems Biology. Nature Publishing Group, 2011. https://doi.org/10.1038/msb.2011.45."},"main_file_link":[{"url":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3159970/","open_access":"1"}],"external_id":{"pmid":["21734646"]},"oa":1,"quality_controlled":"1","month":"07","day":"05"},{"abstract":[{"lang":"eng","text":"Multicellular organisms depend on cell production, cell fate specification, and correct patterning to shape their adult body. In plants, auxin plays a prominent role in the timely coordination of these different cellular processes. A well-studied example is lateral root initiation, in which auxin triggers founder cell specification and cell cycle activation of xylem pole–positioned pericycle cells. Here, we report that the E2Fa transcription factor of Arabidopsis thaliana is an essential component that regulates the asymmetric cell division marking lateral root initiation. Moreover, we demonstrate that E2Fa expression is regulated by the LATERAL ORGAN BOUNDARY DOMAIN18/LATERAL ORGAN BOUNDARY DOMAIN33 (LBD18/LBD33) dimer that is, in turn, regulated by the auxin signaling pathway. LBD18/LBD33 mediates lateral root organogenesis through E2Fa transcriptional activation, whereas E2Fa expression under control of the LBD18 promoter eliminates the need for LBD18. Besides lateral root initiation, vascular patterning is disrupted in E2Fa knockout plants, similarly as it is affected in auxin signaling and lbd mutants, indicating that the transcriptional induction of E2Fa through LBDs represents a general mechanism for auxin-dependent cell cycle activation. Our data illustrate how a conserved mechanism driving cell cycle entry has been adapted evolutionarily to connect auxin signaling with control of processes determining plant architecture. "}],"publist_id":"3598","issue":"10","extern":1,"type":"journal_article","author":[{"first_name":"Barbara","last_name":"Berckmans","full_name":"Berckmans, Barbara"},{"first_name":"Valya","last_name":"Vassileva","full_name":"Vassileva, Valya"},{"full_name":"Schmid, Stephan P","last_name":"Schmid","first_name":"Stephan"},{"full_name":"Maes, Sara","last_name":"Maes","first_name":"Sara"},{"full_name":"Parizot, Boris","first_name":"Boris","last_name":"Parizot"},{"first_name":"Satoshi","last_name":"Naramoto","full_name":"Naramoto, Satoshi"},{"full_name":"Magyar, Zoltan","first_name":"Zoltan","last_name":"Magyar"},{"first_name":"Claire","last_name":"Lessa Alvim Kamei","full_name":"Lessa Alvim Kamei, Claire"},{"last_name":"Koncz","first_name":"Csaba","full_name":"Koncz, Csaba"},{"last_name":"Bögre","first_name":"Laszlo","full_name":"Bögre, Laszlo"},{"first_name":"Geert","last_name":"Persiau","full_name":"Persiau, Geert"},{"full_name":"De Jaeger, Geert","first_name":"Geert","last_name":"De Jaeger"},{"id":"4159519E-F248-11E8-B48F-1D18A9856A87","orcid":"0000-0002-8302-7596","first_name":"Jirí","last_name":"Friml","full_name":"Jirí Friml"},{"first_name":"Rüdiger","last_name":"Simon","full_name":"Simon, Rüdiger"},{"last_name":"Beeckman","first_name":"Tom","full_name":"Beeckman, Tom"},{"last_name":"De Veyldera","first_name":"Lieven","full_name":"de Veyldera, Lieven"}],"date_created":"2018-12-11T12:01:24Z","date_updated":"2021-01-12T07:41:04Z","volume":23,"_id":"3102","year":"2011","title":"Auxin Dependent cell cycle reactivation through transcriptional regulation of arabidopsis E2Fa by lateral organ boundary proteins","publication_status":"published","status":"public","publisher":"American Society of Plant Biologists","intvolume":" 23","day":"14","month":"10","date_published":"2011-10-14T00:00:00Z","doi":"10.1105/tpc.111.088377","publication":"Plant Cell","citation":{"short":"B. Berckmans, V. Vassileva, S. Schmid, S. Maes, B. Parizot, S. Naramoto, Z. Magyar, C. Lessa Alvim Kamei, C. Koncz, L. Bögre, G. Persiau, G. De Jaeger, J. Friml, R. Simon, T. Beeckman, L. De Veyldera, Plant Cell 23 (2011) 3671–3683.","mla":"Berckmans, Barbara, et al. “Auxin Dependent Cell Cycle Reactivation through Transcriptional Regulation of Arabidopsis E2Fa by Lateral Organ Boundary Proteins.” Plant Cell, vol. 23, no. 10, American Society of Plant Biologists, 2011, pp. 3671–83, doi:10.1105/tpc.111.088377.","chicago":"Berckmans, Barbara, Valya Vassileva, Stephan Schmid, Sara Maes, Boris Parizot, Satoshi Naramoto, Zoltan Magyar, et al. “Auxin Dependent Cell Cycle Reactivation through Transcriptional Regulation of Arabidopsis E2Fa by Lateral Organ Boundary Proteins.” Plant Cell. American Society of Plant Biologists, 2011. https://doi.org/10.1105/tpc.111.088377.","ama":"Berckmans B, Vassileva V, Schmid S, et al. Auxin Dependent cell cycle reactivation through transcriptional regulation of arabidopsis E2Fa by lateral organ boundary proteins. Plant Cell. 2011;23(10):3671-3683. doi:10.1105/tpc.111.088377","apa":"Berckmans, B., Vassileva, V., Schmid, S., Maes, S., Parizot, B., Naramoto, S., … De Veyldera, L. (2011). Auxin Dependent cell cycle reactivation through transcriptional regulation of arabidopsis E2Fa by lateral organ boundary proteins. Plant Cell. American Society of Plant Biologists. https://doi.org/10.1105/tpc.111.088377","ieee":"B. Berckmans et al., “Auxin Dependent cell cycle reactivation through transcriptional regulation of arabidopsis E2Fa by lateral organ boundary proteins,” Plant Cell, vol. 23, no. 10. American Society of Plant Biologists, pp. 3671–3683, 2011.","ista":"Berckmans B, Vassileva V, Schmid S, Maes S, Parizot B, Naramoto S, Magyar Z, Lessa Alvim Kamei C, Koncz C, Bögre L, Persiau G, De Jaeger G, Friml J, Simon R, Beeckman T, De Veyldera L. 2011. Auxin Dependent cell cycle reactivation through transcriptional regulation of arabidopsis E2Fa by lateral organ boundary proteins. Plant Cell. 23(10), 3671–3683."},"quality_controlled":0,"page":"3671 - 3683"},{"page":"674 - 682","quality_controlled":"1","citation":{"short":"X. Chen, N. Irani, J. Friml, Current Opinion in Plant Biology 14 (2011) 674–682.","mla":"Chen, Xu, et al. “Clathrin-Mediated Endocytosis: The Gateway into Plant Cells.” Current Opinion in Plant Biology, vol. 14, no. 6, Elsevier, 2011, pp. 674–82, doi:10.1016/j.pbi.2011.08.006.","chicago":"Chen, Xu, Niloufer Irani, and Jiří Friml. “Clathrin-Mediated Endocytosis: The Gateway into Plant Cells.” Current Opinion in Plant Biology. Elsevier, 2011. https://doi.org/10.1016/j.pbi.2011.08.006.","ama":"Chen X, Irani N, Friml J. Clathrin-mediated endocytosis: The gateway into plant cells. Current Opinion in Plant Biology. 2011;14(6):674-682. doi:10.1016/j.pbi.2011.08.006","ieee":"X. Chen, N. Irani, and J. Friml, “Clathrin-mediated endocytosis: The gateway into plant cells,” Current Opinion in Plant Biology, vol. 14, no. 6. Elsevier, pp. 674–682, 2011.","apa":"Chen, X., Irani, N., & Friml, J. (2011). Clathrin-mediated endocytosis: The gateway into plant cells. Current Opinion in Plant Biology. Elsevier. https://doi.org/10.1016/j.pbi.2011.08.006","ista":"Chen X, Irani N, Friml J. 2011. Clathrin-mediated endocytosis: The gateway into plant cells. Current Opinion in Plant Biology. 14(6), 674–682."},"publication":"Current Opinion in Plant Biology","language":[{"iso":"eng"}],"date_published":"2011-12-01T00:00:00Z","doi":"10.1016/j.pbi.2011.08.006","month":"12","day":"01","intvolume":" 14","publisher":"Elsevier","status":"public","publication_status":"published","title":"Clathrin-mediated endocytosis: The gateway into plant cells","_id":"3103","user_id":"3E5EF7F0-F248-11E8-B48F-1D18A9856A87","year":"2011","oa_version":"None","volume":14,"date_created":"2018-12-11T12:01:24Z","date_updated":"2021-01-12T07:41:05Z","author":[{"full_name":"Chen, Xu","last_name":"Chen","first_name":"Xu","id":"4E5ADCAA-F248-11E8-B48F-1D18A9856A87"},{"full_name":"Irani, Niloufer","first_name":"Niloufer","last_name":"Irani"},{"full_name":"Friml, Jirí","id":"4159519E-F248-11E8-B48F-1D18A9856A87","orcid":"0000-0002-8302-7596","first_name":"Jirí","last_name":"Friml"}],"type":"journal_article","extern":"1","publist_id":"3596","issue":"6","abstract":[{"lang":"eng","text":"Endocytosis in plants has an essential role not only for basic cellular functions but also for growth and development, hormonal signaling and communication with the environment including nutrient delivery, toxin avoidance, and pathogen defense. The major endocytic mechanism in plants depends on the coat protein clathrin. It starts by clathrin-coated vesicle formation at the plasma membrane, where specific cargoes are recognized and packaged for internalization. Recently, genetic, biochemical and advanced microscopy studies provided initial insights into mechanisms and roles of clathrin-mediated endocytosis in plants. Here we summarize the present state of knowledge and compare mechanisms of clathrin-mediated endocytosis in plants with animal and yeast paradigms as well as review plant-specific regulations and roles of this process."}]},{"doi":"10.1016/j.cell.2011.06.014","date_published":"2011-07-22T00:00:00Z","publication":"Cell","citation":{"ama":"Liu C, Sage J, Miller M, et al. Mosaic analysis with double markers reveals tumor cell of origin in glioma. Cell. 2011;146(2):209-221. doi:10.1016/j.cell.2011.06.014","apa":"Liu, C., Sage, J., Miller, M., Verhaak, R., Hippenmeyer, S., Vogel, H., … Zong, H. (2011). Mosaic analysis with double markers reveals tumor cell of origin in glioma. Cell. Cell Press. https://doi.org/10.1016/j.cell.2011.06.014","ieee":"C. Liu et al., “Mosaic analysis with double markers reveals tumor cell of origin in glioma,” Cell, vol. 146, no. 2. Cell Press, pp. 209–221, 2011.","ista":"Liu C, Sage J, Miller M, Verhaak R, Hippenmeyer S, Vogel H, Foreman O, Bronson R, Nishiyama A, Luo L, Zong H. 2011. Mosaic analysis with double markers reveals tumor cell of origin in glioma. Cell. 146(2), 209–221.","short":"C. Liu, J. Sage, M. Miller, R. Verhaak, S. Hippenmeyer, H. Vogel, O. Foreman, R. Bronson, A. Nishiyama, L. Luo, H. Zong, Cell 146 (2011) 209–221.","mla":"Liu, Chong, et al. “Mosaic Analysis with Double Markers Reveals Tumor Cell of Origin in Glioma.” Cell, vol. 146, no. 2, Cell Press, 2011, pp. 209–21, doi:10.1016/j.cell.2011.06.014.","chicago":"Liu, Chong, Jonathan Sage, Michael Miller, Roel Verhaak, Simon Hippenmeyer, Hannes Vogel, Oded Foreman, et al. “Mosaic Analysis with Double Markers Reveals Tumor Cell of Origin in Glioma.” Cell. Cell Press, 2011. https://doi.org/10.1016/j.cell.2011.06.014."},"quality_controlled":0,"page":"209 - 221","month":"07","day":"22","author":[{"full_name":"Liu, Chong","first_name":"Chong","last_name":"Liu"},{"first_name":"Jonathan","last_name":"Sage","full_name":"Sage, Jonathan C"},{"full_name":"Miller, Michael R","last_name":"Miller","first_name":"Michael"},{"full_name":"Verhaak, Roel G","first_name":"Roel","last_name":"Verhaak"},{"last_name":"Hippenmeyer","first_name":"Simon","orcid":"0000-0003-2279-1061","id":"37B36620-F248-11E8-B48F-1D18A9856A87","full_name":"Simon Hippenmeyer"},{"full_name":"Vogel, Hannes","first_name":"Hannes","last_name":"Vogel"},{"first_name":"Oded","last_name":"Foreman","full_name":"Foreman, Oded"},{"last_name":"Bronson","first_name":"Roderick","full_name":"Bronson, Roderick T"},{"first_name":"Akiko","last_name":"Nishiyama","full_name":"Nishiyama, Akiko"},{"first_name":"Liqun","last_name":"Luo","full_name":"Luo, Liqun"},{"first_name":"Hui","last_name":"Zong","full_name":"Zong, Hui"}],"date_created":"2018-12-11T12:01:40Z","date_updated":"2021-01-12T07:41:23Z","volume":146,"_id":"3147","year":"2011","title":"Mosaic analysis with double markers reveals tumor cell of origin in glioma","publication_status":"published","status":"public","intvolume":" 146","publisher":"Cell Press","abstract":[{"lang":"eng","text":"Cancer cell of origin is difficult to identify by analyzing cells within terminal stage tumors, whose identity could be concealed by the acquired plasticity. Thus, an ideal approach to identify the cell of origin is to analyze proliferative abnormalities in distinct lineages prior to malignancy. Here, we use mosaic analysis with double markers (MADM) in mice to model gliomagenesis by initiating concurrent p53/Nf1 mutations sporadically in neural stem cells (NSCs). Surprisingly, MADM-based lineage tracing revealed significant aberrant growth prior to malignancy only in oligodendrocyte precursor cells (OPCs), but not in any other NSC-derived lineages or NSCs themselves. Upon tumor formation, phenotypic and transcriptome analyses of tumor cells revealed salient OPC features. Finally, introducing the same p53/Nf1 mutations directly into OPCs consistently led to gliomagenesis. Our findings suggest OPCs as the cell of origin in this model, even when initial mutations occur in NSCs, and highlight the importance of analyzing premalignant stages to identify the cancer cell of origin."}],"issue":"2","publist_id":"3548","extern":1,"type":"journal_article"}]