[{"_id":"14662","status":"public","tmp":{"legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode","image":"/images/cc_by.png","name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)","short":"CC BY (4.0)"},"type":"journal_article","article_type":"original","ddc":["510"],"date_updated":"2023-12-11T12:12:14Z","file_date_updated":"2023-12-11T12:03:12Z","department":[{"_id":"RoSe"}],"oa_version":"None","abstract":[{"text":"We consider a class of polaron models, including the Fröhlich model, at zero total\r\nmomentum, and show that at sufficiently weak coupling there are no excited eigenvalues below\r\nthe essential spectrum.","lang":"eng"}],"intvolume":" 13","month":"11","scopus_import":"1","language":[{"iso":"eng"}],"file":[{"file_name":"2023_JST_Seiringer.pdf","date_created":"2023-12-11T12:03:12Z","creator":"dernst","file_size":201513,"date_updated":"2023-12-11T12:03:12Z","success":1,"file_id":"14677","checksum":"9ce96ca87d56ea9a70d2eb9a32839f8d","relation":"main_file","access_level":"open_access","content_type":"application/pdf"}],"publication_status":"published","publication_identifier":{"issn":["1664-039X"],"eissn":["1664-0403"]},"license":"https://creativecommons.org/licenses/by/4.0/","issue":"3","volume":13,"user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","citation":{"ista":"Seiringer R. 2023. Absence of excited eigenvalues for Fröhlich type polaron models at weak coupling. Journal of Spectral Theory. 13(3), 1045–1055.","chicago":"Seiringer, Robert. “Absence of Excited Eigenvalues for Fröhlich Type Polaron Models at Weak Coupling.” Journal of Spectral Theory. EMS Press, 2023. https://doi.org/10.4171/JST/469.","short":"R. Seiringer, Journal of Spectral Theory 13 (2023) 1045–1055.","ieee":"R. Seiringer, “Absence of excited eigenvalues for Fröhlich type polaron models at weak coupling,” Journal of Spectral Theory, vol. 13, no. 3. EMS Press, pp. 1045–1055, 2023.","apa":"Seiringer, R. (2023). Absence of excited eigenvalues for Fröhlich type polaron models at weak coupling. Journal of Spectral Theory. EMS Press. https://doi.org/10.4171/JST/469","ama":"Seiringer R. Absence of excited eigenvalues for Fröhlich type polaron models at weak coupling. Journal of Spectral Theory. 2023;13(3):1045-1055. doi:10.4171/JST/469","mla":"Seiringer, Robert. “Absence of Excited Eigenvalues for Fröhlich Type Polaron Models at Weak Coupling.” Journal of Spectral Theory, vol. 13, no. 3, EMS Press, 2023, pp. 1045–55, doi:10.4171/JST/469."},"title":"Absence of excited eigenvalues for Fröhlich type polaron models at weak coupling","external_id":{"arxiv":["2210.17123"]},"article_processing_charge":"Yes","author":[{"first_name":"Robert","id":"4AFD0470-F248-11E8-B48F-1D18A9856A87","orcid":"0000-0002-6781-0521","full_name":"Seiringer, Robert","last_name":"Seiringer"}],"oa":1,"quality_controlled":"1","publisher":"EMS Press","publication":"Journal of Spectral Theory","day":"25","year":"2023","has_accepted_license":"1","date_created":"2023-12-10T23:00:59Z","date_published":"2023-11-25T00:00:00Z","doi":"10.4171/JST/469","page":"1045-1055"},{"department":[{"_id":"MaIb"}],"title":"Ab-initio stability of Iridium based newly proposed full and quaternary heusler alloys","article_processing_charge":"No","author":[{"first_name":"Shyam Lal","full_name":"Gupta, Shyam Lal","last_name":"Gupta"},{"first_name":"Saurabh","id":"12d625da-9cb3-11ed-9667-af09d37d3f0a","last_name":"Singh","orcid":"0000-0003-2209-5269","full_name":"Singh, Saurabh"},{"first_name":"Sumit","last_name":"Kumar","full_name":"Kumar, Sumit"},{"full_name":"Anupam, Unknown","last_name":"Anupam","first_name":"Unknown"},{"full_name":"Thakur, Samjeet Singh","last_name":"Thakur","first_name":"Samjeet Singh"},{"first_name":"Ashish","full_name":"Kumar, Ashish","last_name":"Kumar"},{"first_name":"Sanjay","full_name":"Panwar, Sanjay","last_name":"Panwar"},{"first_name":"D.","full_name":"Diwaker, D.","last_name":"Diwaker"}],"user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","citation":{"chicago":"Gupta, Shyam Lal, Saurabh Singh, Sumit Kumar, Unknown Anupam, Samjeet Singh Thakur, Ashish Kumar, Sanjay Panwar, and D. Diwaker. “Ab-Initio Stability of Iridium Based Newly Proposed Full and Quaternary Heusler Alloys.” Physica B: Condensed Matter. Elsevier, 2023. https://doi.org/10.1016/j.physb.2023.415539.","ista":"Gupta SL, Singh S, Kumar S, Anupam U, Thakur SS, Kumar A, Panwar S, Diwaker D. 2023. Ab-initio stability of Iridium based newly proposed full and quaternary heusler alloys. Physica B: Condensed Matter. 674, 415539.","mla":"Gupta, Shyam Lal, et al. “Ab-Initio Stability of Iridium Based Newly Proposed Full and Quaternary Heusler Alloys.” Physica B: Condensed Matter, vol. 674, 415539, Elsevier, 2023, doi:10.1016/j.physb.2023.415539.","short":"S.L. Gupta, S. Singh, S. Kumar, U. Anupam, S.S. Thakur, A. Kumar, S. Panwar, D. Diwaker, Physica B: Condensed Matter 674 (2023).","ieee":"S. L. Gupta et al., “Ab-initio stability of Iridium based newly proposed full and quaternary heusler alloys,” Physica B: Condensed Matter, vol. 674. Elsevier, 2023.","ama":"Gupta SL, Singh S, Kumar S, et al. Ab-initio stability of Iridium based newly proposed full and quaternary heusler alloys. Physica B: Condensed Matter. 2023;674. doi:10.1016/j.physb.2023.415539","apa":"Gupta, S. L., Singh, S., Kumar, S., Anupam, U., Thakur, S. S., Kumar, A., … Diwaker, D. (2023). Ab-initio stability of Iridium based newly proposed full and quaternary heusler alloys. Physica B: Condensed Matter. Elsevier. https://doi.org/10.1016/j.physb.2023.415539"},"date_updated":"2023-12-12T08:22:23Z","status":"public","article_type":"original","type":"journal_article","article_number":"415539","_id":"14652","date_created":"2023-12-10T23:00:56Z","volume":674,"date_published":"2023-11-28T00:00:00Z","doi":"10.1016/j.physb.2023.415539","publication":"Physica B: Condensed Matter","language":[{"iso":"eng"}],"day":"28","publication_status":"epub_ahead","year":"2023","publication_identifier":{"issn":["0921-4526"]},"intvolume":" 674","month":"11","quality_controlled":"1","publisher":"Elsevier","scopus_import":"1","oa_version":"None","abstract":[{"text":"In order to demonstrate the stability of newly proposed iridium-based Ir2Cr(In,Sn) and IrRhCr(In,Sn) heusler alloys, we present ab-initio analysis of these alloys by examining various properties to prove their stability. The stability of these alloys can be inferred from different cohesive and formation energies as well as positive phonon frequencies. Their electronic structure results indicate that they are semi-metals in nature. The magnetic moments are computed using the Slater-Pauling formula and exhibit a high value, with the Cr atom contributing the most in all alloys. Mulliken’s charge analysis results show that our alloys contain a range of linkages, mainly ionic and covalent ones. The ductility and mechanical stability of these alloys are confirmed by elastic constants viz. Poisson’s ratio, Pugh’s ratio, and many different types of elastic moduli.","lang":"eng"}]},{"department":[{"_id":"GaTk"}],"file_date_updated":"2023-10-09T07:23:46Z","ddc":["570"],"date_updated":"2023-12-13T11:11:24Z","status":"public","tmp":{"legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode","image":"/images/cc_by.png","name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)","short":"CC BY (4.0)"},"type":"journal_article","article_type":"original","_id":"12487","ec_funded":1,"issue":"10","volume":26,"language":[{"iso":"eng"}],"file":[{"file_size":4872708,"date_updated":"2023-10-09T07:23:46Z","creator":"dernst","file_name":"2023_iScience_Scarpetta.pdf","date_created":"2023-10-09T07:23:46Z","content_type":"application/pdf","relation":"main_file","access_level":"open_access","success":1,"file_id":"14412","checksum":"f499836af172ecc9865de4bb41fa99d1"}],"publication_status":"published","publication_identifier":{"eissn":["2589-0042"]},"intvolume":" 26","month":"10","scopus_import":"1","pmid":1,"oa_version":"Published Version","abstract":[{"text":"Sleep plays a key role in preserving brain function, keeping the brain network in a state that ensures optimal computational capabilities. Empirical evidence indicates that such a state is consistent with criticality, where scale-free neuronal avalanches emerge. However, the relationship between sleep, emergent avalanches, and criticality remains poorly understood. Here we fully characterize the critical behavior of avalanches during sleep, and study their relationship with the sleep macro- and micro-architecture, in particular the cyclic alternating pattern (CAP). We show that avalanche size and duration distributions exhibit robust power laws with exponents approximately equal to −3/2 e −2, respectively. Importantly, we find that sizes scale as a power law of the durations, and that all critical exponents for neuronal avalanches obey robust scaling relations, which are consistent with the mean-field directed percolation universality class. Our analysis demonstrates that avalanche dynamics depends on the position within the NREM-REM cycles, with the avalanche density increasing in the descending phases and decreasing in the ascending phases of sleep cycles. Moreover, we show that, within NREM sleep, avalanche occurrence correlates with CAP activation phases, particularly A1, which are the expression of slow wave sleep propensity and have been proposed to be beneficial for cognitive processes. The results suggest that neuronal avalanches, and thus tuning to criticality, actively contribute to sleep development and play a role in preserving network function. Such findings, alongside characterization of the universality class for avalanches, open new avenues to the investigation of functional role of criticality during sleep with potential clinical application.Significance statementWe fully characterize the critical behavior of neuronal avalanches during sleep, and show that avalanches follow precise scaling laws that are consistent with the mean-field directed percolation universality class. The analysis provides first evidence of a functional relationship between avalanche occurrence, slow-wave sleep dynamics, sleep stage transitions and occurrence of CAP phase A during NREM sleep. Because CAP is considered one of the major guardians of NREM sleep that allows the brain to dynamically react to external perturbation and contributes to the cognitive consolidation processes occurring in sleep, our observations suggest that neuronal avalanches at criticality are associated with flexible response to external inputs and to cognitive processes, a key assumption of the critical brain hypothesis.","lang":"eng"}],"title":"Criticality of neuronal avalanches in human sleep and their relationship with sleep macro- and micro-architecture","article_processing_charge":"Yes","external_id":{"isi":["001082331200001"],"pmid":["37766992"]},"author":[{"first_name":"Silvia","full_name":"Scarpetta, Silvia","last_name":"Scarpetta"},{"first_name":"Niccolò","full_name":"Morrisi, Niccolò","last_name":"Morrisi"},{"last_name":"Mutti","full_name":"Mutti, Carlotta","first_name":"Carlotta"},{"last_name":"Azzi","full_name":"Azzi, Nicoletta","first_name":"Nicoletta"},{"first_name":"Irene","last_name":"Trippi","full_name":"Trippi, Irene"},{"full_name":"Ciliento, Rosario","last_name":"Ciliento","first_name":"Rosario"},{"full_name":"Apicella, Ilenia","last_name":"Apicella","first_name":"Ilenia"},{"last_name":"Messuti","full_name":"Messuti, Giovanni","first_name":"Giovanni"},{"first_name":"Marianna","full_name":"Angiolelli, Marianna","last_name":"Angiolelli"},{"last_name":"Lombardi","orcid":"0000-0003-2623-5249","full_name":"Lombardi, Fabrizio","id":"A057D288-3E88-11E9-986D-0CF4E5697425","first_name":"Fabrizio"},{"first_name":"Liborio","last_name":"Parrino","full_name":"Parrino, Liborio"},{"first_name":"Anna Elisabetta","last_name":"Vaudano","full_name":"Vaudano, Anna Elisabetta"}],"user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","citation":{"short":"S. Scarpetta, N. Morrisi, C. Mutti, N. Azzi, I. Trippi, R. Ciliento, I. Apicella, G. Messuti, M. Angiolelli, F. Lombardi, L. Parrino, A.E. Vaudano, IScience 26 (2023) 107840.","ieee":"S. Scarpetta et al., “Criticality of neuronal avalanches in human sleep and their relationship with sleep macro- and micro-architecture,” iScience, vol. 26, no. 10. Elsevier, p. 107840, 2023.","apa":"Scarpetta, S., Morrisi, N., Mutti, C., Azzi, N., Trippi, I., Ciliento, R., … Vaudano, A. E. (2023). Criticality of neuronal avalanches in human sleep and their relationship with sleep macro- and micro-architecture. IScience. Elsevier. https://doi.org/10.1016/j.isci.2023.107840","ama":"Scarpetta S, Morrisi N, Mutti C, et al. Criticality of neuronal avalanches in human sleep and their relationship with sleep macro- and micro-architecture. iScience. 2023;26(10):107840. doi:10.1016/j.isci.2023.107840","mla":"Scarpetta, Silvia, et al. “Criticality of Neuronal Avalanches in Human Sleep and Their Relationship with Sleep Macro- and Micro-Architecture.” IScience, vol. 26, no. 10, Elsevier, 2023, p. 107840, doi:10.1016/j.isci.2023.107840.","ista":"Scarpetta S, Morrisi N, Mutti C, Azzi N, Trippi I, Ciliento R, Apicella I, Messuti G, Angiolelli M, Lombardi F, Parrino L, Vaudano AE. 2023. Criticality of neuronal avalanches in human sleep and their relationship with sleep macro- and micro-architecture. iScience. 26(10), 107840.","chicago":"Scarpetta, Silvia, Niccolò Morrisi, Carlotta Mutti, Nicoletta Azzi, Irene Trippi, Rosario Ciliento, Ilenia Apicella, et al. “Criticality of Neuronal Avalanches in Human Sleep and Their Relationship with Sleep Macro- and Micro-Architecture.” IScience. Elsevier, 2023. https://doi.org/10.1016/j.isci.2023.107840."},"project":[{"_id":"260C2330-B435-11E9-9278-68D0E5697425","call_identifier":"H2020","name":"ISTplus - Postdoctoral Fellowships","grant_number":"754411"},{"_id":"eb943429-77a9-11ec-83b8-9f471cdf5c67","grant_number":"M03318","name":"Functional Advantages of Critical Brain Dynamics"}],"date_created":"2023-02-02T10:50:17Z","doi":"10.1016/j.isci.2023.107840","date_published":"2023-10-20T00:00:00Z","page":"107840","publication":"iScience","day":"20","year":"2023","isi":1,"has_accepted_license":"1","oa":1,"quality_controlled":"1","publisher":"Elsevier","acknowledgement":"FL acknowledges support from the European Union’s Horizon 2020 research and innovation program under the Marie Sklodowska-Curie Grant Agreement No. 754411, and from the Austrian Science Fund (FWF) under the Lise Meitner fellowship No. PT1013M03318. IA acknowledges financial support from the MIUR PRIN 2017WZFTZP."},{"date_published":"2023-08-07T00:00:00Z","doi":"10.1186/s12862-023-02137-7","date_created":"2023-02-28T07:38:17Z","isi":1,"has_accepted_license":"1","year":"2023","day":"07","publication":"BMC Ecology and Evolution","quality_controlled":"1","publisher":"Springer Nature","oa":1,"acknowledgement":"We are thankful to Mike Bidochka for the fungal strain, Lukas Schrader for sharing the C. obscurior genome data for primer development, the Lab Support Facility of ISTA for general laboratory support and help with the permit approval procedures, and the Finca El Quinto for letting us collect ants on their property. We thank the Social Immunity Team at ISTA for help with ant collection and experimental help, in particular Elina Hanhimäki and Marta Gorecka for behavioural observation, and Elisabeth Naderlinger for spore load PCRs. We further thank the Social Immunity Team and Jürgen Heinze for continued discussion and comments on the manuscript.\r\nOpen access funding provided by Institute of Science and Technology Austria (ISTA). This project received funding from the European Research Council (ERC) under the European Union’s Horizon 2020 research and innovation programme (grant agreement No 771402 to SC). ","author":[{"first_name":"Sina","id":"48204546-F248-11E8-B48F-1D18A9856A87","last_name":"Metzler","full_name":"Metzler, Sina","orcid":"0000-0002-9547-2494"},{"full_name":"Kirchner, Jessica","last_name":"Kirchner","first_name":"Jessica","id":"21516227-15aa-11ec-9fb2-c6e8ffc155d3"},{"first_name":"Anna V","id":"406F989C-F248-11E8-B48F-1D18A9856A87","full_name":"Grasse, Anna V","last_name":"Grasse"},{"first_name":"Sylvia","id":"2F64EC8C-F248-11E8-B48F-1D18A9856A87","last_name":"Cremer","orcid":"0000-0002-2193-3868","full_name":"Cremer, Sylvia"}],"article_processing_charge":"Yes","external_id":{"isi":["001042643600002"],"pmid":["37550612"]},"title":"Trade-offs between immunity and competitive ability in fighting ant males","citation":{"apa":"Metzler, S., Kirchner, J., Grasse, A. V., & Cremer, S. (2023). Trade-offs between immunity and competitive ability in fighting ant males. BMC Ecology and Evolution. Springer Nature. https://doi.org/10.1186/s12862-023-02137-7","ama":"Metzler S, Kirchner J, Grasse AV, Cremer S. Trade-offs between immunity and competitive ability in fighting ant males. BMC Ecology and Evolution. 2023;23. doi:10.1186/s12862-023-02137-7","ieee":"S. Metzler, J. Kirchner, A. V. Grasse, and S. Cremer, “Trade-offs between immunity and competitive ability in fighting ant males,” BMC Ecology and Evolution, vol. 23. Springer Nature, 2023.","short":"S. Metzler, J. Kirchner, A.V. Grasse, S. Cremer, BMC Ecology and Evolution 23 (2023).","mla":"Metzler, Sina, et al. “Trade-Offs between Immunity and Competitive Ability in Fighting Ant Males.” BMC Ecology and Evolution, vol. 23, 37, Springer Nature, 2023, doi:10.1186/s12862-023-02137-7.","ista":"Metzler S, Kirchner J, Grasse AV, Cremer S. 2023. Trade-offs between immunity and competitive ability in fighting ant males. BMC Ecology and Evolution. 23, 37.","chicago":"Metzler, Sina, Jessica Kirchner, Anna V Grasse, and Sylvia Cremer. “Trade-Offs between Immunity and Competitive Ability in Fighting Ant Males.” BMC Ecology and Evolution. Springer Nature, 2023. https://doi.org/10.1186/s12862-023-02137-7."},"user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","project":[{"_id":"2649B4DE-B435-11E9-9278-68D0E5697425","call_identifier":"H2020","grant_number":"771402","name":"Epidemics in ant societies on a chip"}],"article_number":"37","volume":23,"related_material":{"record":[{"status":"public","id":"12693","relation":"research_data"}]},"ec_funded":1,"publication_identifier":{"issn":["2730-7182"]},"publication_status":"published","file":[{"file_name":"2023_BMCEcology_Metzler.pdf","date_created":"2023-08-14T07:51:47Z","file_size":2004276,"date_updated":"2023-08-14T07:51:47Z","creator":"dernst","success":1,"checksum":"95966dc7d242d2c85bdd4fe14233dbd8","file_id":"14048","content_type":"application/pdf","relation":"main_file","access_level":"open_access"}],"language":[{"iso":"eng"}],"scopus_import":"1","month":"08","intvolume":" 23","abstract":[{"text":"Background: Fighting disease while fighting rivals exposes males to constraints and tradeoffs during male-male competition. We here tested how both the stage and intensity of infection with the fungal pathogen Metarhizium robertsii interfered with fighting success in Cardiocondyla obscurior ant males. Males of this species have evolved long lifespans during which they can gain many matings with the young queens of the colony, if successful in male-male competition. Since male fights occur inside the colony, the outcome of male-male competition can further be biased by interference of the colony’s worker force.\r\nResults: We found that severe, but not yet mild, infection strongly impaired male fighting success. In late-stage infection, this could be attributed to worker aggression directed towards the infected rather than the healthy male and an already very high male morbidity even in the absence of fighting. Shortly after pathogen exposure, however, male mortality was particularly increased during combat. Since these males mounted a strong immune response, their reduced fighting success suggests a trade-off between immune investment and competitive ability already early in the infection. Even if the males themselves showed no difference in the number of attacks they raised against their healthy rivals across infection stages and levels, severely infected males were thus losing in male-male competition from an early stage of infection on.\r\nConclusions: Males of the ant C. obscurior have evolved high immune investment, triggering an effective immune response very fast after fungal exposure. This allows them to cope with mild pathogen exposures without cost to their success in male-male competition, and hence to gain multiple mating opportunities with the emerging virgin queens of the colony. Under severe infection, however, they are weak fighters and rarely survive a combat already at early infection when raising an immune response, as well as at progressed infection, when they are morbid and preferentially targeted by worker aggression. Workers thereby remove males that pose a future disease threat by biasing male-male competition. Our study thus revealed a novel social immunity mechanism how social insect workers protect the colony against disease risk.","lang":"eng"}],"acknowledged_ssus":[{"_id":"LifeSc"}],"oa_version":"Published Version","pmid":1,"department":[{"_id":"SyCr"}],"file_date_updated":"2023-08-14T07:51:47Z","date_updated":"2023-12-13T11:13:14Z","ddc":["570"],"type":"journal_article","article_type":"original","tmp":{"legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode","image":"/images/cc_by.png","name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)","short":"CC BY (4.0)"},"status":"public","_id":"12696"},{"acknowledgement":"This work was carried out within the framework of the EV-K2-CNR and Nepal Academy of Science and Technology. K.Y. was supported by the Second Tibetan Plateau Scientific Expedition and Research Program (grant no. 2019QZKK0206). N.C. was supported by the project NODES, which has received funding from the MUR–M4C2 1.5 of PNRR funded by the European Union - NextGeneration EU (Grant agreement no. ECS00000036). T.E.S. has received funding from the European Union’s Horizon 2020 research and innovation programme under the Marie Sklodowska-Curie grant no. 101026058. F.P. has received funding from the European Research Council under the European Union’s Horizon 2020 research and innovation programme grant no. 772751, RAVEN, ‘Rapid mass losses of debris-covered glaciers in High Mountain Asia’ and has been supported by the SNSF grant ‘High-elevation precipitation in High Mountain Asia’ (grant no. 183633). A.A. was supported by the European Union’s Horizon 2020 research and innovation program under grant agreement no. 101004156 (CONFESS project) and by the European Union’s Horizon Europe research and innovation program under grant agreement no. 101081193 (OptimESM project). We thank H. Wehrli for valuable comments and suggestions and J. Giannitrapani for the graphic support. We thank A. Da Polenza and K. Bista of EV-K2-CNR for believing that studying the high elevations is relevant for the whole globe.","oa":1,"publisher":"Springer Nature","quality_controlled":"1","year":"2023","has_accepted_license":"1","publication":"Nature Geoscience","day":"04","page":"1120-1127","date_created":"2023-12-10T23:00:58Z","doi":"10.1038/s41561-023-01331-y","date_published":"2023-12-04T00:00:00Z","citation":{"chicago":"Salerno, Franco, Nicolas Guyennon, Kun Yang, Thomas Shaw, Changgui Lin, Nicola Colombo, Emanuele Romano, et al. “Local Cooling and Drying Induced by Himalayan Glaciers under Global Warming.” Nature Geoscience. Springer Nature, 2023. https://doi.org/10.1038/s41561-023-01331-y.","ista":"Salerno F, Guyennon N, Yang K, Shaw T, Lin C, Colombo N, Romano E, Gruber S, Bolch T, Alessandri A, Cristofanelli P, Putero D, Diolaiuti G, Tartari G, Verza G, Thakuri S, Balsamo G, Miles ES, Pellicciotti F. 2023. Local cooling and drying induced by Himalayan glaciers under global warming. Nature Geoscience. 16, 1120–1127.","mla":"Salerno, Franco, et al. “Local Cooling and Drying Induced by Himalayan Glaciers under Global Warming.” Nature Geoscience, vol. 16, Springer Nature, 2023, pp. 1120–27, doi:10.1038/s41561-023-01331-y.","ama":"Salerno F, Guyennon N, Yang K, et al. Local cooling and drying induced by Himalayan glaciers under global warming. Nature Geoscience. 2023;16:1120-1127. doi:10.1038/s41561-023-01331-y","apa":"Salerno, F., Guyennon, N., Yang, K., Shaw, T., Lin, C., Colombo, N., … Pellicciotti, F. (2023). Local cooling and drying induced by Himalayan glaciers under global warming. Nature Geoscience. Springer Nature. https://doi.org/10.1038/s41561-023-01331-y","ieee":"F. Salerno et al., “Local cooling and drying induced by Himalayan glaciers under global warming,” Nature Geoscience, vol. 16. Springer Nature, pp. 1120–1127, 2023.","short":"F. Salerno, N. Guyennon, K. Yang, T. Shaw, C. Lin, N. Colombo, E. Romano, S. Gruber, T. Bolch, A. Alessandri, P. Cristofanelli, D. Putero, G. Diolaiuti, G. Tartari, G. Verza, S. Thakuri, G. Balsamo, E.S. Miles, F. Pellicciotti, Nature Geoscience 16 (2023) 1120–1127."},"user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","article_processing_charge":"Yes (in subscription journal)","author":[{"full_name":"Salerno, Franco","last_name":"Salerno","first_name":"Franco"},{"first_name":"Nicolas","last_name":"Guyennon","full_name":"Guyennon, Nicolas"},{"first_name":"Kun","last_name":"Yang","full_name":"Yang, Kun"},{"id":"3caa3f91-1f03-11ee-96ce-e0e553054d6e","first_name":"Thomas","full_name":"Shaw, Thomas","orcid":"0000-0001-7640-6152","last_name":"Shaw"},{"first_name":"Changgui","full_name":"Lin, Changgui","last_name":"Lin"},{"first_name":"Nicola","full_name":"Colombo, Nicola","last_name":"Colombo"},{"first_name":"Emanuele","full_name":"Romano, Emanuele","last_name":"Romano"},{"first_name":"Stephan","full_name":"Gruber, Stephan","last_name":"Gruber"},{"last_name":"Bolch","full_name":"Bolch, Tobias","first_name":"Tobias"},{"last_name":"Alessandri","full_name":"Alessandri, Andrea","first_name":"Andrea"},{"full_name":"Cristofanelli, Paolo","last_name":"Cristofanelli","first_name":"Paolo"},{"first_name":"Davide","last_name":"Putero","full_name":"Putero, Davide"},{"last_name":"Diolaiuti","full_name":"Diolaiuti, Guglielmina","first_name":"Guglielmina"},{"first_name":"Gianni","last_name":"Tartari","full_name":"Tartari, Gianni"},{"first_name":"Gianpietro","full_name":"Verza, Gianpietro","last_name":"Verza"},{"first_name":"Sudeep","full_name":"Thakuri, Sudeep","last_name":"Thakuri"},{"first_name":"Gianpaolo","full_name":"Balsamo, Gianpaolo","last_name":"Balsamo"},{"first_name":"Evan S.","full_name":"Miles, Evan S.","last_name":"Miles"},{"full_name":"Pellicciotti, Francesca","orcid":"0000-0002-5554-8087","last_name":"Pellicciotti","first_name":"Francesca","id":"b28f055a-81ea-11ed-b70c-a9fe7f7b0e70"}],"title":"Local cooling and drying induced by Himalayan glaciers under global warming","abstract":[{"lang":"eng","text":"Understanding the response of Himalayan glaciers to global warming is vital because of their role as a water source for the Asian subcontinent. However, great uncertainties still exist on the climate drivers of past and present glacier changes across scales. Here, we analyse continuous hourly climate station data from a glacierized elevation (Pyramid station, Mount Everest) since 1994 together with other ground observations and climate reanalysis. We show that a decrease in maximum air temperature and precipitation occurred during the last three decades at Pyramid in response to global warming. Reanalysis data suggest a broader occurrence of this effect in the glacierized areas of the Himalaya. We hypothesize that the counterintuitive cooling is caused by enhanced sensible heat exchange and the associated increase in glacier katabatic wind, which draws cool air downward from higher elevations. The stronger katabatic winds have also lowered the elevation of local wind convergence, thereby diminishing precipitation in glacial areas and negatively affecting glacier mass balance. This local cooling may have partially preserved glaciers from melting and could help protect the periglacial environment."}],"oa_version":"Published Version","scopus_import":"1","intvolume":" 16","month":"12","publication_status":"published","publication_identifier":{"issn":["1752-0894"],"eissn":["1752-0908"]},"language":[{"iso":"eng"}],"file":[{"creator":"dernst","file_size":6072603,"date_updated":"2023-12-11T10:11:19Z","file_name":"2023_NatureGeoscience_Salerno.pdf","date_created":"2023-12-11T10:11:19Z","relation":"main_file","access_level":"open_access","content_type":"application/pdf","success":1,"file_id":"14671","checksum":"d5ae0d17069eebc6f454c8608cf83e21"}],"volume":16,"related_material":{"link":[{"description":"News on ISTA website","relation":"press_release","url":"https://ista.ac.at/en/news/wind-of-climate-change/"}]},"_id":"14659","tmp":{"legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode","image":"/images/cc_by.png","name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)","short":"CC BY (4.0)"},"article_type":"original","type":"journal_article","status":"public","date_updated":"2023-12-13T11:01:10Z","ddc":["550"],"department":[{"_id":"FrPe"}],"file_date_updated":"2023-12-11T10:11:19Z"},{"file_date_updated":"2023-04-03T06:38:56Z","department":[{"_id":"PeJo"}],"date_updated":"2023-12-13T11:15:58Z","ddc":["570"],"type":"journal_article","article_type":"original","tmp":{"legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode","image":"/images/cc_by.png","name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)","short":"CC BY (4.0)"},"status":"public","_id":"12786","volume":14,"publication_identifier":{"eissn":["2041-1723"]},"publication_status":"published","file":[{"file_id":"12797","checksum":"0a97b31191432dae5853bbb5ccb7698d","success":1,"content_type":"application/pdf","access_level":"open_access","relation":"main_file","date_created":"2023-04-03T06:38:56Z","file_name":"2023_NatureComm_Zhang.pdf","date_updated":"2023-04-03T06:38:56Z","file_size":2613996,"creator":"dernst"}],"language":[{"iso":"eng"}],"scopus_import":"1","month":"03","intvolume":" 14","abstract":[{"lang":"eng","text":"AMPA glutamate receptors (AMPARs) mediate excitatory neurotransmission throughout the brain. Their signalling is uniquely diversified by brain region-specific auxiliary subunits, providing an opportunity for the development of selective therapeutics. AMPARs associated with TARP γ8 are enriched in the hippocampus, and are targets of emerging anti-epileptic drugs. To understand their therapeutic activity, we determined cryo-EM structures of the GluA1/2-γ8 receptor associated with three potent, chemically diverse ligands. We find that despite sharing a lipid-exposed and water-accessible binding pocket, drug action is differentially affected by binding-site mutants. Together with patch-clamp recordings and MD simulations we also demonstrate that ligand-triggered reorganisation of the AMPAR-TARP interface contributes to modulation. Unexpectedly, one ligand (JNJ-61432059) acts bifunctionally, negatively affecting GluA1 but exerting positive modulatory action on GluA2-containing AMPARs, in a TARP stoichiometry-dependent manner. These results further illuminate the action of TARPs, demonstrate the sensitive balance between positive and negative modulatory action, and provide a mechanistic platform for development of both positive and negative selective AMPAR modulators."}],"oa_version":"Published Version","author":[{"last_name":"Zhang","full_name":"Zhang, Danyang","first_name":"Danyang"},{"full_name":"Lape, Remigijus","last_name":"Lape","first_name":"Remigijus"},{"full_name":"Shaikh, Saher A.","last_name":"Shaikh","first_name":"Saher A."},{"first_name":"Bianka K.","last_name":"Kohegyi","full_name":"Kohegyi, Bianka K."},{"id":"63836096-4690-11EA-BD4E-32803DDC885E","first_name":"Jake","last_name":"Watson","orcid":"0000-0002-8698-3823","full_name":"Watson, Jake"},{"last_name":"Cais","full_name":"Cais, Ondrej","first_name":"Ondrej"},{"first_name":"Terunaga","full_name":"Nakagawa, Terunaga","last_name":"Nakagawa"},{"first_name":"Ingo H.","full_name":"Greger, Ingo H.","last_name":"Greger"}],"external_id":{"isi":["001066658700003"]},"article_processing_charge":"No","title":"Modulatory mechanisms of TARP γ8-selective AMPA receptor therapeutics","citation":{"ista":"Zhang D, Lape R, Shaikh SA, Kohegyi BK, Watson J, Cais O, Nakagawa T, Greger IH. 2023. Modulatory mechanisms of TARP γ8-selective AMPA receptor therapeutics. Nature Communications. 14, 1659.","chicago":"Zhang, Danyang, Remigijus Lape, Saher A. Shaikh, Bianka K. Kohegyi, Jake Watson, Ondrej Cais, Terunaga Nakagawa, and Ingo H. Greger. “Modulatory Mechanisms of TARP Γ8-Selective AMPA Receptor Therapeutics.” Nature Communications. Springer Nature, 2023. https://doi.org/10.1038/s41467-023-37259-5.","apa":"Zhang, D., Lape, R., Shaikh, S. A., Kohegyi, B. K., Watson, J., Cais, O., … Greger, I. H. (2023). Modulatory mechanisms of TARP γ8-selective AMPA receptor therapeutics. Nature Communications. Springer Nature. https://doi.org/10.1038/s41467-023-37259-5","ama":"Zhang D, Lape R, Shaikh SA, et al. Modulatory mechanisms of TARP γ8-selective AMPA receptor therapeutics. Nature Communications. 2023;14. doi:10.1038/s41467-023-37259-5","short":"D. Zhang, R. Lape, S.A. Shaikh, B.K. Kohegyi, J. Watson, O. Cais, T. Nakagawa, I.H. Greger, Nature Communications 14 (2023).","ieee":"D. Zhang et al., “Modulatory mechanisms of TARP γ8-selective AMPA receptor therapeutics,” Nature Communications, vol. 14. Springer Nature, 2023.","mla":"Zhang, Danyang, et al. “Modulatory Mechanisms of TARP Γ8-Selective AMPA Receptor Therapeutics.” Nature Communications, vol. 14, 1659, Springer Nature, 2023, doi:10.1038/s41467-023-37259-5."},"user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","article_number":"1659","date_published":"2023-03-25T00:00:00Z","doi":"10.1038/s41467-023-37259-5","date_created":"2023-04-02T22:01:09Z","has_accepted_license":"1","isi":1,"year":"2023","day":"25","publication":"Nature Communications","quality_controlled":"1","publisher":"Springer Nature","oa":1,"acknowledgement":"We thank James Krieger for generating the ‘proDy’ interaction maps in Fig. 5B and S7C, and Jan-Niklas Dohrke for critically reading the manuscript. We thank members of the Greger lab for insightful comments during this study. We acknowledge Trevor Rutherford for confirming ligand integrity by NMR. We are also grateful to LMB scientific computing and the EM facility for their support. This research was funded in part by the Wellcome Trust (223194/Z/21/Z) to I.H.G. For the purpose of Open Access, the MRC Laboratory of Molecular Biology has applied a CC BY public copyright licence to any Author Accepted Manuscript (AAM) version arising from this submission. Further funding came from the Medical Research Council (MRU105174197) to I.H.G, and NIH grant (R56/R01MH123474) to T.N."},{"month":"02","oa":1,"publisher":"Institute of Science and Technology Austria","oa_version":"Published Version","abstract":[{"text":"See Readme File for further information.","lang":"eng"}],"license":"https://creativecommons.org/licenses/by-nc/4.0/","contributor":[{"last_name":"Metzler","contributor_type":"data_collector","id":"48204546-F248-11E8-B48F-1D18A9856A87","first_name":"Sina"},{"last_name":"Kirchner","first_name":"Jessica","id":"21516227-15aa-11ec-9fb2-c6e8ffc155d3","contributor_type":"data_collector"},{"id":"406F989C-F248-11E8-B48F-1D18A9856A87","contributor_type":"data_collector","first_name":"Anna V","last_name":"Grasse"}],"date_created":"2023-02-28T06:38:37Z","related_material":{"record":[{"relation":"used_in_publication","id":"12696","status":"public"}]},"date_published":"2023-02-28T00:00:00Z","doi":"10.15479/AT:ISTA:12693","file":[{"date_updated":"2023-02-28T06:34:08Z","file_size":77070,"creator":"scremer","date_created":"2023-02-28T06:34:08Z","file_name":"Metzler_ReadMe.pdf","content_type":"application/pdf","access_level":"open_access","relation":"main_file","checksum":"c1565d655ca05601acfd84e0d12b8563","file_id":"12694","success":1},{"content_type":"application/vnd.openxmlformats-officedocument.spreadsheetml.sheet","relation":"main_file","access_level":"open_access","success":1,"file_id":"12695","checksum":"75c4c4948563d6261cb7548f80d909f1","file_size":88001,"date_updated":"2023-02-28T06:34:12Z","creator":"scremer","file_name":"Metzler_RepositoryData.xlsx","date_created":"2023-02-28T06:34:12Z"}],"day":"28","year":"2023","has_accepted_license":"1","status":"public","tmp":{"legal_code_url":"https://creativecommons.org/licenses/by-nc/4.0/legalcode","image":"/images/cc_by_nc.png","name":"Creative Commons Attribution-NonCommercial 4.0 International (CC BY-NC 4.0)","short":"CC BY-NC (4.0)"},"type":"research_data","_id":"12693","department":[{"_id":"SyCr"}],"title":"Source data for Metzler et al, 2023: Trade-offs between immunity and competitive ability in fighting ant males ","file_date_updated":"2023-02-28T06:34:12Z","article_processing_charge":"No","author":[{"orcid":"0000-0002-2193-3868","full_name":"Cremer, Sylvia","last_name":"Cremer","id":"2F64EC8C-F248-11E8-B48F-1D18A9856A87","first_name":"Sylvia"}],"user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","ddc":["570"],"date_updated":"2023-12-13T11:13:13Z","citation":{"ama":"Cremer S. Source data for Metzler et al, 2023: Trade-offs between immunity and competitive ability in fighting ant males . 2023. doi:10.15479/AT:ISTA:12693","apa":"Cremer, S. (2023). Source data for Metzler et al, 2023: Trade-offs between immunity and competitive ability in fighting ant males . Institute of Science and Technology Austria. https://doi.org/10.15479/AT:ISTA:12693","ieee":"S. Cremer, “Source data for Metzler et al, 2023: Trade-offs between immunity and competitive ability in fighting ant males .” Institute of Science and Technology Austria, 2023.","short":"S. Cremer, (2023).","mla":"Cremer, Sylvia. Source Data for Metzler et Al, 2023: Trade-Offs between Immunity and Competitive Ability in Fighting Ant Males . Institute of Science and Technology Austria, 2023, doi:10.15479/AT:ISTA:12693.","ista":"Cremer S. 2023. Source data for Metzler et al, 2023: Trade-offs between immunity and competitive ability in fighting ant males , Institute of Science and Technology Austria, 10.15479/AT:ISTA:12693.","chicago":"Cremer, Sylvia. “Source Data for Metzler et Al, 2023: Trade-Offs between Immunity and Competitive Ability in Fighting Ant Males .” Institute of Science and Technology Austria, 2023. https://doi.org/10.15479/AT:ISTA:12693."}},{"publisher":"Springer Nature","quality_controlled":"1","oa":1,"acknowledgement":"This work received support from the European Union-funded Horizon Europe project ‘environMENTAL’ (no. 101057429 to G.S., A.M. and M.M.N.) and cofunding by UK Research and Innovation under the UK Government’s Horizon Europe funding guarantee (nos. 10041392 and 10038599) for study design and data analysis; the Horizon 2020-funded European Research Council Advanced Grant ‘STRATIFY’ (no. 695313 to G.S. for study design and data analysis); the Human Brain Project (HBP SGA3, no. 945539 to G.S. for study design and data analysis); the National Institutes of Health (grant no. R01DA049238 to G.S. for study design and data analysis); the German Research Foundation (COPE; grant no. 675346 to G.S. for study design and data analysis); the National Natural Science Foundation of China (grant no. 82001797 to J.X., grant no. 82030053 to C.Y., grant no. 82202093 to J.T. and grant no. 82150710554 to G.S. for study design, data analysis and preparation of the manuscript); National Key Research and Development Program of China (grant no. 2018YFC1314301 to C.Y. for study design and data analysis); Tianjin Applied Basic Research Diversified Investment Foundation (grant no. 21JCYBJC01360 to J.X. for study design and data analysis); Tianjin Health Technology Project (grant no. TJWJ2021QN002 to J.X. for preparation of the manuscript); Science & Technology Development Fund of the Tianjin Education Commission for Higher Education (grant no. 2019KJ195 to J.X. for preparation of the manuscript); the Tianjin Medical University ‘Clinical Talent Training 123 Climbing Plan’ to J.X. for the preparation of the manuscript; Tianjin Key Medical Discipline (Specialty) Construction Project (grant no. TJYXZDXK-001A to C.Y. for preparation of the manuscript); the National Key R&D Program of China (grant no. 2022YFE0209400 to L.Y. for study design and data analysis); the Tsinghua University Initiative Scientific Research Program (grant no. 2021Z11GHX002 to L.Y. for study design and data analysis); the National Key Scientific and Technological Infrastructure Project ‘Earth System Science Numerical Simulator Facility’ (EarthLab to L.Y. for study design and data analysis); the Chinese National High-end Foreign Expert Recruitment Plan to G.S.; and the Alexander von Humboldt Foundation to G.S. for study design and data analysis.","page":"1456-1467","doi":"10.1038/s41591-023-02365-w","date_published":"2023-06-15T00:00:00Z","date_created":"2023-06-25T22:00:46Z","isi":1,"has_accepted_license":"1","year":"2023","day":"15","publication":"Nature Medicine","author":[{"first_name":"Jiayuan","full_name":"Xu, Jiayuan","last_name":"Xu"},{"full_name":"Liu, Nana","last_name":"Liu","first_name":"Nana"},{"first_name":"Elli","last_name":"Polemiti","full_name":"Polemiti, Elli"},{"first_name":"Liliana","full_name":"Garcia-Mondragon, Liliana","last_name":"Garcia-Mondragon"},{"full_name":"Tang, Jie","last_name":"Tang","first_name":"Jie"},{"first_name":"Xiaoxuan","full_name":"Liu, Xiaoxuan","last_name":"Liu"},{"first_name":"Tristram","full_name":"Lett, Tristram","last_name":"Lett"},{"full_name":"Yu, Le","last_name":"Yu","first_name":"Le"},{"full_name":"Nöthen, Markus M.","last_name":"Nöthen","first_name":"Markus M."},{"full_name":"Feng, Jianfeng","last_name":"Feng","first_name":"Jianfeng"},{"first_name":"Chunshui","last_name":"Yu","full_name":"Yu, Chunshui"},{"first_name":"Andre","full_name":"Marquand, Andre","last_name":"Marquand"},{"first_name":"Gunter","full_name":"Schumann, Gunter","last_name":"Schumann"},{"first_name":"Henrik","last_name":"Walter","full_name":"Walter, Henrik"},{"last_name":"Heinz","full_name":"Heinz, Andreas","first_name":"Andreas"},{"full_name":"Ralser, Markus","last_name":"Ralser","first_name":"Markus"},{"last_name":"Twardziok","full_name":"Twardziok, Sven","first_name":"Sven"},{"first_name":"Nilakshi","last_name":"Vaidya","full_name":"Vaidya, Nilakshi"},{"first_name":"Emin","full_name":"Serin, Emin","last_name":"Serin"},{"last_name":"Jentsch","full_name":"Jentsch, Marcel","first_name":"Marcel"},{"first_name":"Esther","full_name":"Hitchen, Esther","last_name":"Hitchen"},{"full_name":"Eils, Roland","last_name":"Eils","first_name":"Roland"},{"first_name":"Ulrike Helene","last_name":"Taron","full_name":"Taron, Ulrike Helene"},{"full_name":"Schütz, Tatjana","last_name":"Schütz","first_name":"Tatjana"},{"first_name":"Kerstin","last_name":"Schepanski","full_name":"Schepanski, Kerstin"},{"first_name":"Jamie","full_name":"Banks, Jamie","last_name":"Banks"},{"full_name":"Banaschewski, Tobias","last_name":"Banaschewski","first_name":"Tobias"},{"full_name":"Jansone, Karina","last_name":"Jansone","first_name":"Karina"},{"last_name":"Christmann","full_name":"Christmann, Nina","first_name":"Nina"},{"first_name":"Andreas","last_name":"Meyer-Lindenberg","full_name":"Meyer-Lindenberg, Andreas"},{"full_name":"Tost, Heike","last_name":"Tost","first_name":"Heike"},{"first_name":"Nathalie","full_name":"Holz, Nathalie","last_name":"Holz"},{"full_name":"Schwarz, Emanuel","last_name":"Schwarz","first_name":"Emanuel"},{"full_name":"Stringaris, Argyris","last_name":"Stringaris","first_name":"Argyris"},{"first_name":"Maja","last_name":"Neidhart","full_name":"Neidhart, Maja"},{"first_name":"Frauke","last_name":"Nees","full_name":"Nees, Frauke"},{"first_name":"Sebastian","last_name":"Siehl","full_name":"Siehl, Sebastian"},{"first_name":"Ole","full_name":"A. Andreassen, Ole","last_name":"A. Andreassen"},{"first_name":"Lars","last_name":"T. Westlye","full_name":"T. Westlye, Lars"},{"full_name":"Van Der Meer, Dennis","last_name":"Van Der Meer","first_name":"Dennis"},{"first_name":"Sara","last_name":"Fernandez","full_name":"Fernandez, Sara"},{"first_name":"Rikka","last_name":"Kjelkenes","full_name":"Kjelkenes, Rikka"},{"last_name":"Ask","full_name":"Ask, Helga","first_name":"Helga"},{"full_name":"Rapp, Michael","last_name":"Rapp","first_name":"Michael"},{"first_name":"Mira","full_name":"Tschorn, Mira","last_name":"Tschorn"},{"first_name":"Sarah Jane","full_name":"Böttger, Sarah Jane","last_name":"Böttger"},{"last_name":"Novarino","full_name":"Novarino, Gaia","orcid":"0000-0002-7673-7178","id":"3E57A680-F248-11E8-B48F-1D18A9856A87","first_name":"Gaia"},{"first_name":"Lena","id":"4406F586-F248-11E8-B48F-1D18A9856A87","full_name":"Marr, Lena","last_name":"Marr"},{"first_name":"Mel","full_name":"Slater, Mel","last_name":"Slater"},{"last_name":"Viapiana","full_name":"Viapiana, Guillem Feixas","first_name":"Guillem Feixas"},{"full_name":"Orosa, Francisco Eiroa","last_name":"Orosa","first_name":"Francisco Eiroa"},{"last_name":"Gallego","full_name":"Gallego, Jaime","first_name":"Jaime"},{"first_name":"Alvaro","last_name":"Pastor","full_name":"Pastor, Alvaro"},{"full_name":"Forstner, Andreas","last_name":"Forstner","first_name":"Andreas"},{"last_name":"Hoffmann","full_name":"Hoffmann, Per","first_name":"Per"},{"full_name":"M. Nöthen, Markus","last_name":"M. Nöthen","first_name":"Markus"},{"first_name":"Andreas","last_name":"J. Forstner","full_name":"J. Forstner, Andreas"},{"first_name":"Isabelle","last_name":"Claus","full_name":"Claus, Isabelle"},{"first_name":"Abbi","last_name":"Miller","full_name":"Miller, Abbi"},{"first_name":"Stefanie","full_name":"Heilmann-Heimbach, Stefanie","last_name":"Heilmann-Heimbach"},{"first_name":"Peter","full_name":"Sommer, Peter","last_name":"Sommer"},{"last_name":"Boye","full_name":"Boye, Mona","first_name":"Mona"},{"last_name":"Wilbertz","full_name":"Wilbertz, Johannes","first_name":"Johannes"},{"first_name":"Karen","last_name":"Schmitt","full_name":"Schmitt, Karen"},{"full_name":"Jirsa, Viktor","last_name":"Jirsa","first_name":"Viktor"},{"last_name":"Petkoski","full_name":"Petkoski, Spase","first_name":"Spase"},{"first_name":"Séverine","full_name":"Pitel, Séverine","last_name":"Pitel"},{"first_name":"Lisa","full_name":"Otten, Lisa","last_name":"Otten"},{"last_name":"Athanasiadis","full_name":"Athanasiadis, Anastasios Polykarpos","first_name":"Anastasios Polykarpos"},{"first_name":"Charlie","full_name":"Pearmund, Charlie","last_name":"Pearmund"},{"full_name":"Spanlang, Bernhard","last_name":"Spanlang","first_name":"Bernhard"},{"last_name":"Alvarez","full_name":"Alvarez, Elena","first_name":"Elena"},{"last_name":"Sanchez","full_name":"Sanchez, Mavi","first_name":"Mavi"},{"last_name":"Giner","full_name":"Giner, Arantxa","first_name":"Arantxa"},{"full_name":"Hese, Sören","last_name":"Hese","first_name":"Sören"},{"last_name":"Renner","full_name":"Renner, Paul","first_name":"Paul"},{"last_name":"Jia","full_name":"Jia, Tianye","first_name":"Tianye"},{"last_name":"Gong","full_name":"Gong, Yanting","first_name":"Yanting"},{"first_name":"Yunman","full_name":"Xia, Yunman","last_name":"Xia"},{"full_name":"Chang, Xiao","last_name":"Chang","first_name":"Xiao"},{"last_name":"Calhoun","full_name":"Calhoun, Vince","first_name":"Vince"},{"last_name":"Liu","full_name":"Liu, Jingyu","first_name":"Jingyu"},{"first_name":"Paul","full_name":"Thompson, Paul","last_name":"Thompson"},{"full_name":"Clinton, Nicholas","last_name":"Clinton","first_name":"Nicholas"},{"full_name":"Desrivieres, Sylvane","last_name":"Desrivieres","first_name":"Sylvane"},{"first_name":"Allan","last_name":"H. Young","full_name":"H. Young, Allan"},{"last_name":"Stahl","full_name":"Stahl, Bernd","first_name":"Bernd"},{"full_name":"Ogoh, George","last_name":"Ogoh","first_name":"George"}],"article_processing_charge":"No","external_id":{"isi":["001013172700001"]},"title":"Effects of urban living environments on mental health in adults","citation":{"mla":"Xu, Jiayuan, et al. “Effects of Urban Living Environments on Mental Health in Adults.” Nature Medicine, vol. 29, Springer Nature, 2023, pp. 1456–67, doi:10.1038/s41591-023-02365-w.","ieee":"J. Xu et al., “Effects of urban living environments on mental health in adults,” Nature Medicine, vol. 29. Springer Nature, pp. 1456–1467, 2023.","short":"J. Xu, N. Liu, E. Polemiti, L. Garcia-Mondragon, J. Tang, X. Liu, T. Lett, L. Yu, M.M. Nöthen, J. Feng, C. Yu, A. Marquand, G. Schumann, H. Walter, A. Heinz, M. Ralser, S. Twardziok, N. Vaidya, E. Serin, M. Jentsch, E. Hitchen, R. Eils, U.H. Taron, T. Schütz, K. Schepanski, J. Banks, T. Banaschewski, K. Jansone, N. Christmann, A. Meyer-Lindenberg, H. Tost, N. Holz, E. Schwarz, A. Stringaris, M. Neidhart, F. Nees, S. Siehl, O. A. Andreassen, L. T. Westlye, D. Van Der Meer, S. Fernandez, R. Kjelkenes, H. Ask, M. Rapp, M. Tschorn, S.J. Böttger, G. Novarino, L. Marr, M. Slater, G.F. Viapiana, F.E. Orosa, J. Gallego, A. Pastor, A. Forstner, P. Hoffmann, M. M. Nöthen, A. J. Forstner, I. Claus, A. Miller, S. Heilmann-Heimbach, P. Sommer, M. Boye, J. Wilbertz, K. Schmitt, V. Jirsa, S. Petkoski, S. Pitel, L. Otten, A.P. Athanasiadis, C. Pearmund, B. Spanlang, E. Alvarez, M. Sanchez, A. Giner, S. Hese, P. Renner, T. Jia, Y. Gong, Y. Xia, X. Chang, V. Calhoun, J. Liu, P. Thompson, N. Clinton, S. Desrivieres, A. H. Young, B. Stahl, G. Ogoh, Nature Medicine 29 (2023) 1456–1467.","ama":"Xu J, Liu N, Polemiti E, et al. Effects of urban living environments on mental health in adults. Nature Medicine. 2023;29:1456-1467. doi:10.1038/s41591-023-02365-w","apa":"Xu, J., Liu, N., Polemiti, E., Garcia-Mondragon, L., Tang, J., Liu, X., … Ogoh, G. (2023). Effects of urban living environments on mental health in adults. Nature Medicine. Springer Nature. https://doi.org/10.1038/s41591-023-02365-w","chicago":"Xu, Jiayuan, Nana Liu, Elli Polemiti, Liliana Garcia-Mondragon, Jie Tang, Xiaoxuan Liu, Tristram Lett, et al. “Effects of Urban Living Environments on Mental Health in Adults.” Nature Medicine. Springer Nature, 2023. https://doi.org/10.1038/s41591-023-02365-w.","ista":"Xu J, Liu N, Polemiti E, Garcia-Mondragon L, Tang J, Liu X, Lett T, Yu L, Nöthen MM, Feng J, Yu C, Marquand A, Schumann G, Walter H, Heinz A, Ralser M, Twardziok S, Vaidya N, Serin E, Jentsch M, Hitchen E, Eils R, Taron UH, Schütz T, Schepanski K, Banks J, Banaschewski T, Jansone K, Christmann N, Meyer-Lindenberg A, Tost H, Holz N, Schwarz E, Stringaris A, Neidhart M, Nees F, Siehl S, A. Andreassen O, T. Westlye L, Van Der Meer D, Fernandez S, Kjelkenes R, Ask H, Rapp M, Tschorn M, Böttger SJ, Novarino G, Marr L, Slater M, Viapiana GF, Orosa FE, Gallego J, Pastor A, Forstner A, Hoffmann P, M. Nöthen M, J. Forstner A, Claus I, Miller A, Heilmann-Heimbach S, Sommer P, Boye M, Wilbertz J, Schmitt K, Jirsa V, Petkoski S, Pitel S, Otten L, Athanasiadis AP, Pearmund C, Spanlang B, Alvarez E, Sanchez M, Giner A, Hese S, Renner P, Jia T, Gong Y, Xia Y, Chang X, Calhoun V, Liu J, Thompson P, Clinton N, Desrivieres S, H. Young A, Stahl B, Ogoh G. 2023. Effects of urban living environments on mental health in adults. Nature Medicine. 29, 1456–1467."},"user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","scopus_import":"1","month":"06","intvolume":" 29","abstract":[{"lang":"eng","text":"Urban-living individuals are exposed to many environmental factors that may combine and interact to influence mental health. While individual factors of an urban environment have been investigated in isolation, no attempt has been made to model how complex, real-life exposure to living in the city relates to brain and mental health, and how this is moderated by genetic factors. Using the data of 156,075 participants from the UK Biobank, we carried out sparse canonical correlation analyses to investigate the relationships between urban environments and psychiatric symptoms. We found an environmental profile of social deprivation, air pollution, street network and urban land-use density that was positively correlated with an affective symptom group (r = 0.22, Pperm < 0.001), mediated by brain volume differences consistent with reward processing, and moderated by genes enriched for stress response, including CRHR1, explaining 2.01% of the variance in brain volume differences. Protective factors such as greenness and generous destination accessibility were negatively correlated with an anxiety symptom group (r = 0.10, Pperm < 0.001), mediated by brain regions necessary for emotion regulation and moderated by EXD3, explaining 1.65% of the variance. The third urban environmental profile was correlated with an emotional instability symptom group (r = 0.03, Pperm < 0.001). Our findings suggest that different environmental profiles of urban living may influence specific psychiatric symptom groups through distinct neurobiological pathways."}],"oa_version":"Published Version","volume":29,"publication_identifier":{"eissn":["1546-170X"],"issn":["1078-8956"]},"publication_status":"published","file":[{"date_updated":"2023-06-26T10:15:44Z","file_size":7365360,"creator":"dernst","date_created":"2023-06-26T10:15:44Z","file_name":"2023_NatureMedicine_Xu.pdf","content_type":"application/pdf","access_level":"open_access","relation":"main_file","file_id":"13171","checksum":"bcd3225b2731c3442fa98987fd3bd46d","success":1}],"language":[{"iso":"eng"}],"article_type":"original","type":"journal_article","tmp":{"legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode","image":"/images/cc_by.png","name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)","short":"CC BY (4.0)"},"status":"public","_id":"13168","department":[{"_id":"GaNo"}],"file_date_updated":"2023-06-26T10:15:44Z","date_updated":"2023-12-13T11:25:55Z","ddc":["570"]},{"month":"07","intvolume":" 2023","scopus_import":"1","oa_version":"Submitted Version","abstract":[{"lang":"eng","text":"3D printing based on continuous deposition of materials, such as filament-based 3D printing, has seen widespread adoption thanks to its versatility in working with a wide range of materials. An important shortcoming of this type of technology is its limited multi-material capabilities. While there are simple hardware designs that enable multi-material printing in principle, the required software is heavily underdeveloped. A typical hardware design fuses together individual materials fed into a single chamber from multiple inlets before they are deposited. This design, however, introduces a time delay between the intended material mixture and its actual deposition. In this work, inspired by diverse path planning research in robotics, we show that this mechanical challenge can be addressed via improved printer control. We propose to formulate the search for optimal multi-material printing policies in a reinforcement\r\nlearning setup. We put forward a simple numerical deposition model that takes into account the non-linear material mixing and delayed material deposition. To validate our system we focus on color fabrication, a problem known for its strict requirements for varying material mixtures at a high spatial frequency. We demonstrate that our learned control policy outperforms state-of-the-art hand-crafted algorithms."}],"volume":2023,"file":[{"content_type":"application/pdf","relation":"main_file","access_level":"open_access","success":1,"checksum":"daeaa67124777d88487f933ea3f77164","file_id":"12977","file_size":5367986,"date_updated":"2023-05-16T09:12:05Z","creator":"mpiovarc","file_name":"Liao2023.pdf","date_created":"2023-05-16T09:12:05Z"}],"language":[{"iso":"eng"}],"publication_identifier":{"eisbn":["9798350323658"],"issn":["1050-4729"]},"publication_status":"published","status":"public","keyword":["reinforcement learning","deposition","control","color","multi-filament"],"type":"conference","conference":{"name":"ICRA: International Conference on Robotics and Automation","location":"London, United Kingdom","end_date":"2023-06-02","start_date":"2023-05-29"},"_id":"12976","file_date_updated":"2023-05-16T09:12:05Z","department":[{"_id":"BeBi"}],"ddc":["004"],"date_updated":"2023-12-13T11:20:00Z","quality_controlled":"1","publisher":"IEEE","oa":1,"acknowledgement":"This work is graciously supported by FWF Lise Meitner (Grant M 3319). Kang Liao sincerely thank Emiliano Luci, Chunyu Lin, and Yao Zhao for their huge support.","doi":"10.1109/ICRA48891.2023.10160465","date_published":"2023-07-04T00:00:00Z","date_created":"2023-05-16T09:14:09Z","page":"12345-12352","day":"04","publication":"2023 IEEE International Conference on Robotics and Automation","isi":1,"has_accepted_license":"1","year":"2023","project":[{"grant_number":"M03319","name":"Perception-Aware Appearance Fabrication","_id":"eb901961-77a9-11ec-83b8-f5c883a62027"}],"title":"Learning deposition policies for fused multi-material 3D printing","author":[{"first_name":"Kang","last_name":"Liao","full_name":"Liao, Kang"},{"last_name":"Tricard","full_name":"Tricard, Thibault","first_name":"Thibault"},{"last_name":"Piovarci","full_name":"Piovarci, Michael","orcid":"0000-0002-5062-4474","first_name":"Michael","id":"62E473F4-5C99-11EA-A40E-AF823DDC885E"},{"last_name":"Seidel","full_name":"Seidel, Hans-Peter","first_name":"Hans-Peter"},{"full_name":"Babaei, Vahid","last_name":"Babaei","first_name":"Vahid"}],"article_processing_charge":"No","external_id":{"isi":["001048371104068"]},"user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","citation":{"mla":"Liao, Kang, et al. “Learning Deposition Policies for Fused Multi-Material 3D Printing.” 2023 IEEE International Conference on Robotics and Automation, vol. 2023, IEEE, 2023, pp. 12345–52, doi:10.1109/ICRA48891.2023.10160465.","apa":"Liao, K., Tricard, T., Piovarci, M., Seidel, H.-P., & Babaei, V. (2023). Learning deposition policies for fused multi-material 3D printing. In 2023 IEEE International Conference on Robotics and Automation (Vol. 2023, pp. 12345–12352). London, United Kingdom: IEEE. https://doi.org/10.1109/ICRA48891.2023.10160465","ama":"Liao K, Tricard T, Piovarci M, Seidel H-P, Babaei V. Learning deposition policies for fused multi-material 3D printing. In: 2023 IEEE International Conference on Robotics and Automation. Vol 2023. IEEE; 2023:12345-12352. doi:10.1109/ICRA48891.2023.10160465","short":"K. Liao, T. Tricard, M. Piovarci, H.-P. Seidel, V. Babaei, in:, 2023 IEEE International Conference on Robotics and Automation, IEEE, 2023, pp. 12345–12352.","ieee":"K. Liao, T. Tricard, M. Piovarci, H.-P. Seidel, and V. Babaei, “Learning deposition policies for fused multi-material 3D printing,” in 2023 IEEE International Conference on Robotics and Automation, London, United Kingdom, 2023, vol. 2023, pp. 12345–12352.","chicago":"Liao, Kang, Thibault Tricard, Michael Piovarci, Hans-Peter Seidel, and Vahid Babaei. “Learning Deposition Policies for Fused Multi-Material 3D Printing.” In 2023 IEEE International Conference on Robotics and Automation, 2023:12345–52. IEEE, 2023. https://doi.org/10.1109/ICRA48891.2023.10160465.","ista":"Liao K, Tricard T, Piovarci M, Seidel H-P, Babaei V. 2023. Learning deposition policies for fused multi-material 3D printing. 2023 IEEE International Conference on Robotics and Automation. ICRA: International Conference on Robotics and Automation vol. 2023, 12345–12352."}},{"acknowledgement":"We thank Manfred Schartl for sharing RNA-seq data from medaka ovaries and testes prior to publication; Maria Novatchkova for help with RNA-seq analysis; Katharina Lust for advice on medaka techniques; Milan Malinsky for input on Lake Malawi cichlid Bouncer sequences; Felicia Spitzer, Mirjam Binner, and Anna Bandura for help with genotyping; Friedrich Puhl, Kerstin Rattner, Julia Koenig, and Dijana Sunjic for taking care of zebrafish and medaka; and the Pauli lab for helpful discussions about the project and feedback on the manuscript. K.R.B.G. was supported by a DOC Fellowship from the Austrian Academy of Sciences. Work in the Pauli lab was supported by the FWF START program (Y 1031-B28 to A.P.), the ERC CoG 101044495/GaMe, the HFSP Career Development Award (CDA00066/2015 to A.P.), a HFSP Young Investigator Award (RGY0079/2020 to A.P.) and the FWF SFB RNA-Deco (project number F80). The IMP receives institutional funding from Boehringer Ingelheim and the Austrian Research Promotion Agency (Headquarter grant FFG-852936). Work by J.S. and Y.M. in this project was supported by the Israel Science Foundation grant 636/21 to Y.M. Work by L.J. was supported by the Swedish Research Council grant 2020-04936 and the Knut and Alice Wallenberg Foundation grant 2018.0042. For the purpose of Open Access, the author has applied a CC BY public copyright license to any Author Accepted Manuscript (AAM) version arising from this submission.","oa":1,"quality_controlled":"1","publisher":"Springer Nature","year":"2023","has_accepted_license":"1","isi":1,"publication":"Nature Communications","day":"14","date_created":"2023-06-25T22:00:45Z","date_published":"2023-06-14T00:00:00Z","doi":"10.1038/s41467-023-39317-4","article_number":"3506","citation":{"ista":"Gert KRB, Panser K, Surm J, Steinmetz BS, Schleiffer A, Jovine L, Moran Y, Kondrashov F, Pauli A. 2023. Divergent molecular signatures in fish Bouncer proteins define cross-fertilization boundaries. Nature Communications. 14, 3506.","chicago":"Gert, Krista R.B., Karin Panser, Joachim Surm, Benjamin S. Steinmetz, Alexander Schleiffer, Luca Jovine, Yehu Moran, Fyodor Kondrashov, and Andrea Pauli. “Divergent Molecular Signatures in Fish Bouncer Proteins Define Cross-Fertilization Boundaries.” Nature Communications. Springer Nature, 2023. https://doi.org/10.1038/s41467-023-39317-4.","ama":"Gert KRB, Panser K, Surm J, et al. Divergent molecular signatures in fish Bouncer proteins define cross-fertilization boundaries. Nature Communications. 2023;14. doi:10.1038/s41467-023-39317-4","apa":"Gert, K. R. B., Panser, K., Surm, J., Steinmetz, B. S., Schleiffer, A., Jovine, L., … Pauli, A. (2023). Divergent molecular signatures in fish Bouncer proteins define cross-fertilization boundaries. Nature Communications. Springer Nature. https://doi.org/10.1038/s41467-023-39317-4","short":"K.R.B. Gert, K. Panser, J. Surm, B.S. Steinmetz, A. Schleiffer, L. Jovine, Y. Moran, F. Kondrashov, A. Pauli, Nature Communications 14 (2023).","ieee":"K. R. B. Gert et al., “Divergent molecular signatures in fish Bouncer proteins define cross-fertilization boundaries,” Nature Communications, vol. 14. Springer Nature, 2023.","mla":"Gert, Krista R. B., et al. “Divergent Molecular Signatures in Fish Bouncer Proteins Define Cross-Fertilization Boundaries.” Nature Communications, vol. 14, 3506, Springer Nature, 2023, doi:10.1038/s41467-023-39317-4."},"user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","article_processing_charge":"No","external_id":{"isi":["001048208600023"]},"author":[{"first_name":"Krista R.B.","last_name":"Gert","full_name":"Gert, Krista R.B."},{"first_name":"Karin","full_name":"Panser, Karin","last_name":"Panser"},{"first_name":"Joachim","full_name":"Surm, Joachim","last_name":"Surm"},{"full_name":"Steinmetz, Benjamin S.","last_name":"Steinmetz","first_name":"Benjamin S."},{"first_name":"Alexander","last_name":"Schleiffer","full_name":"Schleiffer, Alexander"},{"last_name":"Jovine","full_name":"Jovine, Luca","first_name":"Luca"},{"first_name":"Yehu","full_name":"Moran, Yehu","last_name":"Moran"},{"id":"44FDEF62-F248-11E8-B48F-1D18A9856A87","first_name":"Fyodor","orcid":"0000-0001-8243-4694","full_name":"Kondrashov, Fyodor","last_name":"Kondrashov"},{"first_name":"Andrea","last_name":"Pauli","full_name":"Pauli, Andrea"}],"title":"Divergent molecular signatures in fish Bouncer proteins define cross-fertilization boundaries","abstract":[{"lang":"eng","text":"Molecular compatibility between gametes is a prerequisite for successful fertilization. As long as a sperm and egg can recognize and bind each other via their surface proteins, gamete fusion may occur even between members of separate species, resulting in hybrids that can impact speciation. The egg membrane protein Bouncer confers species specificity to gamete interactions between medaka and zebrafish, preventing their cross-fertilization. Here, we leverage this specificity to uncover distinct amino acid residues and N-glycosylation patterns that differentially influence the function of medaka and zebrafish Bouncer and contribute to cross-species incompatibility. Curiously, in contrast to the specificity observed for medaka and zebrafish Bouncer, seahorse and fugu Bouncer are compatible with both zebrafish and medaka sperm, in line with the pervasive purifying selection that dominates Bouncer’s evolution. The Bouncer-sperm interaction is therefore the product of seemingly opposing evolutionary forces that, for some species, restrict fertilization to closely related fish, and for others, allow broad gamete compatibility that enables hybridization."}],"oa_version":"Published Version","scopus_import":"1","intvolume":" 14","month":"06","publication_status":"published","publication_identifier":{"eissn":["2041-1723"]},"language":[{"iso":"eng"}],"file":[{"date_created":"2023-06-26T10:26:04Z","file_name":"2023_NatureComm_Gert.pdf","creator":"dernst","date_updated":"2023-06-26T10:26:04Z","file_size":1555006,"checksum":"d6165f41c7f1c2c04b04256ec9f003fb","file_id":"13172","success":1,"access_level":"open_access","relation":"main_file","content_type":"application/pdf"}],"volume":14,"_id":"13164","tmp":{"legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode","image":"/images/cc_by.png","name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)","short":"CC BY (4.0)"},"type":"journal_article","article_type":"original","status":"public","date_updated":"2023-12-13T11:26:34Z","ddc":["570"],"file_date_updated":"2023-06-26T10:26:04Z","department":[{"_id":"FyKo"}]}]