[{"department":[{"_id":"JuFi"}],"file_date_updated":"2021-04-06T09:31:28Z","ddc":["510"],"date_updated":"2023-08-07T14:31:59Z","status":"public","tmp":{"legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode","image":"/images/cc_by.png","name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)","short":"CC BY (4.0)"},"type":"journal_article","article_type":"original","_id":"9307","ec_funded":1,"license":"https://creativecommons.org/licenses/by/4.0/","volume":9,"language":[{"iso":"eng"}],"file":[{"file_size":727005,"date_updated":"2021-04-06T09:31:28Z","creator":"dernst","file_name":"2021_StochPartDiffEquation_Hensel.pdf","date_created":"2021-04-06T09:31:28Z","content_type":"application/pdf","relation":"main_file","access_level":"open_access","success":1,"file_id":"9309","checksum":"6529b609c9209861720ffa4685111bc6"}],"publication_status":"published","publication_identifier":{"eissn":["2194-041X"],"issn":["2194-0401"]},"intvolume":" 9","month":"03","scopus_import":"1","oa_version":"Published Version","abstract":[{"lang":"eng","text":"We establish finite time extinction with probability one for weak solutions of the Cauchy–Dirichlet problem for the 1D stochastic porous medium equation with Stratonovich transport noise and compactly supported smooth initial datum. Heuristically, this is expected to hold because Brownian motion has average spread rate O(t12) whereas the support of solutions to the deterministic PME grows only with rate O(t1m+1). The rigorous proof relies on a contraction principle up to time-dependent shift for Wong–Zakai type approximations, the transformation to a deterministic PME with two copies of a Brownian path as the lateral boundary, and techniques from the theory of viscosity solutions."}],"title":"Finite time extinction for the 1D stochastic porous medium equation with transport noise","article_processing_charge":"Yes (via OA deal)","external_id":{"isi":["000631001700001"]},"author":[{"id":"4D23B7DA-F248-11E8-B48F-1D18A9856A87","first_name":"Sebastian","orcid":"0000-0001-7252-8072","full_name":"Hensel, Sebastian","last_name":"Hensel"}],"user_id":"4359f0d1-fa6c-11eb-b949-802e58b17ae8","citation":{"chicago":"Hensel, Sebastian. “Finite Time Extinction for the 1D Stochastic Porous Medium Equation with Transport Noise.” Stochastics and Partial Differential Equations: Analysis and Computations. Springer Nature, 2021. https://doi.org/10.1007/s40072-021-00188-9.","ista":"Hensel S. 2021. Finite time extinction for the 1D stochastic porous medium equation with transport noise. Stochastics and Partial Differential Equations: Analysis and Computations. 9, 892–939.","mla":"Hensel, Sebastian. “Finite Time Extinction for the 1D Stochastic Porous Medium Equation with Transport Noise.” Stochastics and Partial Differential Equations: Analysis and Computations, vol. 9, Springer Nature, 2021, pp. 892–939, doi:10.1007/s40072-021-00188-9.","ama":"Hensel S. Finite time extinction for the 1D stochastic porous medium equation with transport noise. Stochastics and Partial Differential Equations: Analysis and Computations. 2021;9:892–939. doi:10.1007/s40072-021-00188-9","apa":"Hensel, S. (2021). Finite time extinction for the 1D stochastic porous medium equation with transport noise. Stochastics and Partial Differential Equations: Analysis and Computations. Springer Nature. https://doi.org/10.1007/s40072-021-00188-9","short":"S. Hensel, Stochastics and Partial Differential Equations: Analysis and Computations 9 (2021) 892–939.","ieee":"S. Hensel, “Finite time extinction for the 1D stochastic porous medium equation with transport noise,” Stochastics and Partial Differential Equations: Analysis and Computations, vol. 9. Springer Nature, pp. 892–939, 2021."},"project":[{"name":"International IST Doctoral Program","grant_number":"665385","call_identifier":"H2020","_id":"2564DBCA-B435-11E9-9278-68D0E5697425"}],"date_created":"2021-04-04T22:01:21Z","date_published":"2021-03-21T00:00:00Z","doi":"10.1007/s40072-021-00188-9","page":"892–939","publication":"Stochastics and Partial Differential Equations: Analysis and Computations","day":"21","year":"2021","isi":1,"has_accepted_license":"1","oa":1,"publisher":"Springer Nature","quality_controlled":"1","acknowledgement":"This project has received funding from the European Union’s Horizon 2020 research and innovation programme under the Marie Skłodowska-Curie Grant Agreement No. 665385 . I am very grateful to M. Gerencsér and J. Maas for proposing this problem as well as helpful discussions. Special thanks go to F. Cornalba for suggesting the additional κ-truncation in Proposition 5. I am also indebted to an anonymous referee for pointing out a gap in a previous version of the proof of Lemma 9 (concerning the treatment of the noise term). The issue is resolved in this version."},{"date_created":"2021-03-28T22:01:42Z","date_published":"2021-03-17T00:00:00Z","doi":"10.1017/jfm.2021.89","publication":"Journal of Fluid Mechanics","day":"17","year":"2021","isi":1,"oa":1,"publisher":"Cambridge University Press","quality_controlled":"1","acknowledgement":"We gratefully acknowledge Joran Rolland, Yohann Duguet, Romain Monchaux, S´ebastien Gom´e, Laurette Tuckerman, Dwight Barkley, Olivier Dauchot and Sabine Bottin for fruitful discussions. We thank Xavier Benoit-Gonin, Amaury Fourgeaud, Thierry Darnige, Olivier Brouard and Justine Laurent for technical help. This work has benefited from the ANR TransFlow, and by starting grants obtained by B.S. from CNRS (INSIS) and ESPCI. T.M. was\r\nsupported by a Joliot visiting professorship grant from ESPCI.","title":"Decay of streaks and rolls in plane Couette-Poiseuille flow","article_processing_charge":"No","external_id":{"arxiv":["2008.08851"],"isi":["000629677500001"]},"author":[{"full_name":"Liu, T.","last_name":"Liu","first_name":"T."},{"last_name":"Semin","full_name":"Semin, B.","first_name":"B."},{"first_name":"Lukasz","id":"2C9AF1C2-F248-11E8-B48F-1D18A9856A87","orcid":"0000-0003-1740-7635","full_name":"Klotz, Lukasz","last_name":"Klotz"},{"first_name":"R.","full_name":"Godoy-Diana, R.","last_name":"Godoy-Diana"},{"full_name":"Wesfreid, J. E.","last_name":"Wesfreid","first_name":"J. E."},{"last_name":"Mullin","full_name":"Mullin, T.","first_name":"T."}],"user_id":"4359f0d1-fa6c-11eb-b949-802e58b17ae8","citation":{"mla":"Liu, T., et al. “Decay of Streaks and Rolls in Plane Couette-Poiseuille Flow.” Journal of Fluid Mechanics, vol. 915, A65, Cambridge University Press, 2021, doi:10.1017/jfm.2021.89.","ieee":"T. Liu, B. Semin, L. Klotz, R. Godoy-Diana, J. E. Wesfreid, and T. Mullin, “Decay of streaks and rolls in plane Couette-Poiseuille flow,” Journal of Fluid Mechanics, vol. 915. Cambridge University Press, 2021.","short":"T. Liu, B. Semin, L. Klotz, R. Godoy-Diana, J.E. Wesfreid, T. Mullin, Journal of Fluid Mechanics 915 (2021).","ama":"Liu T, Semin B, Klotz L, Godoy-Diana R, Wesfreid JE, Mullin T. Decay of streaks and rolls in plane Couette-Poiseuille flow. Journal of Fluid Mechanics. 2021;915. doi:10.1017/jfm.2021.89","apa":"Liu, T., Semin, B., Klotz, L., Godoy-Diana, R., Wesfreid, J. E., & Mullin, T. (2021). Decay of streaks and rolls in plane Couette-Poiseuille flow. Journal of Fluid Mechanics. Cambridge University Press. https://doi.org/10.1017/jfm.2021.89","chicago":"Liu, T., B. Semin, Lukasz Klotz, R. Godoy-Diana, J. E. Wesfreid, and T. Mullin. “Decay of Streaks and Rolls in Plane Couette-Poiseuille Flow.” Journal of Fluid Mechanics. Cambridge University Press, 2021. https://doi.org/10.1017/jfm.2021.89.","ista":"Liu T, Semin B, Klotz L, Godoy-Diana R, Wesfreid JE, Mullin T. 2021. Decay of streaks and rolls in plane Couette-Poiseuille flow. Journal of Fluid Mechanics. 915, A65."},"article_number":"A65","volume":915,"language":[{"iso":"eng"}],"publication_status":"published","publication_identifier":{"eissn":["1469-7645"],"issn":["0022-1120"]},"intvolume":" 915","month":"03","main_file_link":[{"url":"https://arxiv.org/abs/2008.08851","open_access":"1"}],"scopus_import":"1","oa_version":"Preprint","abstract":[{"lang":"eng","text":"We report the results of an experimental investigation into the decay of turbulence in plane Couette–Poiseuille flow using ‘quench’ experiments where the flow laminarises after a sudden reduction in Reynolds number Re. Specifically, we study the velocity field in the streamwise–spanwise plane. We show that the spanwise velocity containing rolls decays faster than the streamwise velocity, which displays elongated regions of higher or lower velocity called streaks. At final Reynolds numbers above 425, the decay of streaks displays two stages: first a slow decay when rolls are present and secondly a more rapid decay of streaks alone. The difference in behaviour results from the regeneration of streaks by rolls, called the lift-up effect. We define the turbulent fraction as the portion of the flow containing turbulence and this is estimated by thresholding the spanwise velocity component. It decreases linearly with time in the whole range of final Re. The corresponding decay slope increases linearly with final Re. The extrapolated value at which this decay slope vanishes is Reaz≈656±10, close to Reg≈670 at which turbulence is self-sustained. The decay of the energy computed from the spanwise velocity component is found to be exponential. The corresponding decay rate increases linearly with Re, with an extrapolated vanishing value at ReAz≈688±10. This value is also close to the value at which the turbulence is self-sustained, showing that valuable information on the transition can be obtained over a wide range of Re."}],"department":[{"_id":"BjHo"}],"date_updated":"2023-08-07T14:30:11Z","status":"public","type":"journal_article","article_type":"original","_id":"9297"},{"acknowledgement":"We thank two reviewers for their corrections and suggestions on the original version of this\r\npaper. This project has received funding from NSERC Grant 50503-10940-500 and from the European Union’s Horizon 2020 research and innovation programme under the Marie SkłodowskaCurie grant agreement No 754411, IST, Klosterneuburg, Austria.","oa":1,"quality_controlled":"1","publisher":"Wiley","publication":"Journal of Graph Theory","day":"23","year":"2021","isi":1,"date_created":"2021-03-28T22:01:41Z","date_published":"2021-03-23T00:00:00Z","doi":"10.1002/jgt.22665","page":"426-440","project":[{"call_identifier":"H2020","_id":"260C2330-B435-11E9-9278-68D0E5697425","grant_number":"754411","name":"ISTplus - Postdoctoral Fellowships"}],"user_id":"4359f0d1-fa6c-11eb-b949-802e58b17ae8","citation":{"ista":"Arroyo Guevara AM, Mcquillan D, Richter RB, Salazar G, Sullivan M. 2021. Drawings of complete graphs in the projective plane. Journal of Graph Theory. 97(3), 426–440.","chicago":"Arroyo Guevara, Alan M, Dan Mcquillan, R. Bruce Richter, Gelasio Salazar, and Matthew Sullivan. “Drawings of Complete Graphs in the Projective Plane.” Journal of Graph Theory. Wiley, 2021. https://doi.org/10.1002/jgt.22665.","ieee":"A. M. Arroyo Guevara, D. Mcquillan, R. B. Richter, G. Salazar, and M. Sullivan, “Drawings of complete graphs in the projective plane,” Journal of Graph Theory, vol. 97, no. 3. Wiley, pp. 426–440, 2021.","short":"A.M. Arroyo Guevara, D. Mcquillan, R.B. Richter, G. Salazar, M. Sullivan, Journal of Graph Theory 97 (2021) 426–440.","ama":"Arroyo Guevara AM, Mcquillan D, Richter RB, Salazar G, Sullivan M. Drawings of complete graphs in the projective plane. Journal of Graph Theory. 2021;97(3):426-440. doi:10.1002/jgt.22665","apa":"Arroyo Guevara, A. M., Mcquillan, D., Richter, R. B., Salazar, G., & Sullivan, M. (2021). Drawings of complete graphs in the projective plane. Journal of Graph Theory. Wiley. https://doi.org/10.1002/jgt.22665","mla":"Arroyo Guevara, Alan M., et al. “Drawings of Complete Graphs in the Projective Plane.” Journal of Graph Theory, vol. 97, no. 3, Wiley, 2021, pp. 426–40, doi:10.1002/jgt.22665."},"title":"Drawings of complete graphs in the projective plane","external_id":{"arxiv":["2002.02287"],"isi":["000631693200001"]},"article_processing_charge":"No","author":[{"id":"3207FDC6-F248-11E8-B48F-1D18A9856A87","first_name":"Alan M","full_name":"Arroyo Guevara, Alan M","orcid":"0000-0003-2401-8670","last_name":"Arroyo Guevara"},{"last_name":"Mcquillan","full_name":"Mcquillan, Dan","first_name":"Dan"},{"first_name":"R. Bruce","last_name":"Richter","full_name":"Richter, R. Bruce"},{"first_name":"Gelasio","full_name":"Salazar, Gelasio","last_name":"Salazar"},{"full_name":"Sullivan, Matthew","last_name":"Sullivan","first_name":"Matthew"}],"oa_version":"Preprint","abstract":[{"text":"Hill's Conjecture states that the crossing number cr(𝐾𝑛) of the complete graph 𝐾𝑛 in the plane (equivalently, the sphere) is 14⌊𝑛2⌋⌊𝑛−12⌋⌊𝑛−22⌋⌊𝑛−32⌋=𝑛4/64+𝑂(𝑛3) . Moon proved that the expected number of crossings in a spherical drawing in which the points are randomly distributed and joined by geodesics is precisely 𝑛4/64+𝑂(𝑛3) , thus matching asymptotically the conjectured value of cr(𝐾𝑛) . Let cr𝑃(𝐺) denote the crossing number of a graph 𝐺 in the projective plane. Recently, Elkies proved that the expected number of crossings in a naturally defined random projective plane drawing of 𝐾𝑛 is (𝑛4/8𝜋2)+𝑂(𝑛3) . In analogy with the relation of Moon's result to Hill's conjecture, Elkies asked if lim𝑛→∞ cr𝑃(𝐾𝑛)/𝑛4=1/8𝜋2 . We construct drawings of 𝐾𝑛 in the projective plane that disprove this.","lang":"eng"}],"intvolume":" 97","month":"03","main_file_link":[{"url":"https://arxiv.org/abs/2002.02287","open_access":"1"}],"scopus_import":"1","language":[{"iso":"eng"}],"publication_status":"published","publication_identifier":{"issn":["0364-9024"],"eissn":["1097-0118"]},"ec_funded":1,"volume":97,"issue":"3","_id":"9295","status":"public","type":"journal_article","article_type":"original","date_updated":"2023-08-07T14:26:15Z","department":[{"_id":"UlWa"}]},{"oa_version":"Published Version","pmid":1,"abstract":[{"lang":"eng","text":"In this issue of Developmental Cell, Doyle and colleagues identify periodic anterior contraction as a characteristic feature of fibroblasts and mesenchymal cancer cells embedded in 3D collagen gels. This contractile mechanism generates a matrix prestrain required for crawling in fibrous 3D environments."}],"intvolume":" 56","month":"03","main_file_link":[{"url":"https://doi.org/10.1016/j.devcel.2021.03.002","open_access":"1"}],"scopus_import":"1","language":[{"iso":"eng"}],"publication_status":"published","publication_identifier":{"issn":["15345807"],"eissn":["18781551"]},"issue":"6","volume":56,"_id":"9294","status":"public","type":"journal_article","article_type":"original","date_updated":"2023-08-07T14:26:47Z","department":[{"_id":"MiSi"}],"oa":1,"publisher":"Elsevier","quality_controlled":"1","publication":"Developmental Cell","day":"22","year":"2021","isi":1,"date_created":"2021-03-28T22:01:41Z","doi":"10.1016/j.devcel.2021.03.002","date_published":"2021-03-22T00:00:00Z","page":"723-725","user_id":"4359f0d1-fa6c-11eb-b949-802e58b17ae8","citation":{"chicago":"Gärtner, Florian R, and Michael K Sixt. “Engaging the Front Wheels to Drive through Fibrous Terrain.” Developmental Cell. Elsevier, 2021. https://doi.org/10.1016/j.devcel.2021.03.002.","ista":"Gärtner FR, Sixt MK. 2021. Engaging the front wheels to drive through fibrous terrain. Developmental Cell. 56(6), 723–725.","mla":"Gärtner, Florian R., and Michael K. Sixt. “Engaging the Front Wheels to Drive through Fibrous Terrain.” Developmental Cell, vol. 56, no. 6, Elsevier, 2021, pp. 723–25, doi:10.1016/j.devcel.2021.03.002.","ama":"Gärtner FR, Sixt MK. Engaging the front wheels to drive through fibrous terrain. Developmental Cell. 2021;56(6):723-725. doi:10.1016/j.devcel.2021.03.002","apa":"Gärtner, F. R., & Sixt, M. K. (2021). Engaging the front wheels to drive through fibrous terrain. Developmental Cell. Elsevier. https://doi.org/10.1016/j.devcel.2021.03.002","ieee":"F. R. Gärtner and M. K. Sixt, “Engaging the front wheels to drive through fibrous terrain,” Developmental Cell, vol. 56, no. 6. Elsevier, pp. 723–725, 2021.","short":"F.R. Gärtner, M.K. Sixt, Developmental Cell 56 (2021) 723–725."},"title":"Engaging the front wheels to drive through fibrous terrain","article_processing_charge":"No","external_id":{"pmid":["33756118"],"isi":["000631681200004"]},"author":[{"id":"397A88EE-F248-11E8-B48F-1D18A9856A87","first_name":"Florian R","orcid":"0000-0001-6120-3723","full_name":"Gärtner, Florian R","last_name":"Gärtner"},{"first_name":"Michael K","id":"41E9FBEA-F248-11E8-B48F-1D18A9856A87","last_name":"Sixt","full_name":"Sixt, Michael K","orcid":"0000-0002-6620-9179"}]},{"doi":"10.1016/j.jneumeth.2021.109125","date_published":"2021-03-09T00:00:00Z","date_created":"2021-04-18T22:01:39Z","isi":1,"has_accepted_license":"1","year":"2021","day":"09","publication":"Journal of Neuroscience Methods","quality_controlled":"1","publisher":"Elsevier","oa":1,"acknowledgement":"This project has received funding from the European Research Council (ERC) under the European Union’s Horizon 2020 research and innovation programme (grant agreement number 692692 to P.J.) and the Fond zur Förderung der Wissenschaftlichen Forschung (Z 312-B27, Wittgenstein award to P.J.). We thank Drs. Jozsef Csicsvari, Christoph Lampert, and Federico Stella for critically reading previous manuscript versions. We are also grateful to Drs. Josh Merel and Ben Shababo for their help with applying the Bayesian detection method to our data. We also thank Florian Marr for technical assistance, Eleftheria Kralli-Beller for manuscript editing, and the Scientific Service Units of IST Austria for efficient support.","author":[{"id":"423EC9C2-F248-11E8-B48F-1D18A9856A87","first_name":"Xiaomin","full_name":"Zhang, Xiaomin","last_name":"Zhang"},{"id":"45BF87EE-F248-11E8-B48F-1D18A9856A87","first_name":"Alois","full_name":"Schlögl, Alois","orcid":"0000-0002-5621-8100","last_name":"Schlögl"},{"id":"3AE48E0A-F248-11E8-B48F-1D18A9856A87","first_name":"David H","orcid":"0000-0001-7577-1676","full_name":"Vandael, David H","last_name":"Vandael"},{"first_name":"Peter M","id":"353C1B58-F248-11E8-B48F-1D18A9856A87","last_name":"Jonas","orcid":"0000-0001-5001-4804","full_name":"Jonas, Peter M"}],"article_processing_charge":"Yes (via OA deal)","external_id":{"isi":["000661088500005"]},"title":"MOD: A novel machine-learning optimal-filtering method for accurate and efficient detection of subthreshold synaptic events in vivo","citation":{"chicago":"Zhang, Xiaomin, Alois Schlögl, David H Vandael, and Peter M Jonas. “MOD: A Novel Machine-Learning Optimal-Filtering Method for Accurate and Efficient Detection of Subthreshold Synaptic Events in Vivo.” Journal of Neuroscience Methods. Elsevier, 2021. https://doi.org/10.1016/j.jneumeth.2021.109125.","ista":"Zhang X, Schlögl A, Vandael DH, Jonas PM. 2021. MOD: A novel machine-learning optimal-filtering method for accurate and efficient detection of subthreshold synaptic events in vivo. Journal of Neuroscience Methods. 357(6), 109125.","mla":"Zhang, Xiaomin, et al. “MOD: A Novel Machine-Learning Optimal-Filtering Method for Accurate and Efficient Detection of Subthreshold Synaptic Events in Vivo.” Journal of Neuroscience Methods, vol. 357, no. 6, 109125, Elsevier, 2021, doi:10.1016/j.jneumeth.2021.109125.","apa":"Zhang, X., Schlögl, A., Vandael, D. H., & Jonas, P. M. (2021). MOD: A novel machine-learning optimal-filtering method for accurate and efficient detection of subthreshold synaptic events in vivo. Journal of Neuroscience Methods. Elsevier. https://doi.org/10.1016/j.jneumeth.2021.109125","ama":"Zhang X, Schlögl A, Vandael DH, Jonas PM. MOD: A novel machine-learning optimal-filtering method for accurate and efficient detection of subthreshold synaptic events in vivo. Journal of Neuroscience Methods. 2021;357(6). doi:10.1016/j.jneumeth.2021.109125","short":"X. Zhang, A. Schlögl, D.H. Vandael, P.M. Jonas, Journal of Neuroscience Methods 357 (2021).","ieee":"X. Zhang, A. Schlögl, D. H. Vandael, and P. M. Jonas, “MOD: A novel machine-learning optimal-filtering method for accurate and efficient detection of subthreshold synaptic events in vivo,” Journal of Neuroscience Methods, vol. 357, no. 6. Elsevier, 2021."},"user_id":"4359f0d1-fa6c-11eb-b949-802e58b17ae8","project":[{"call_identifier":"H2020","_id":"25B7EB9E-B435-11E9-9278-68D0E5697425","grant_number":"692692","name":"Biophysics and circuit function of a giant cortical glumatergic synapse"},{"call_identifier":"FWF","_id":"25C5A090-B435-11E9-9278-68D0E5697425","grant_number":"Z00312","name":"The Wittgenstein Prize"}],"article_number":"109125","volume":357,"issue":"6","license":"https://creativecommons.org/licenses/by-nc-nd/4.0/","ec_funded":1,"publication_identifier":{"eissn":["1872-678X"],"issn":["0165-0270"]},"publication_status":"published","file":[{"date_created":"2021-04-19T08:30:22Z","file_name":"2021_JourNeuroscienceMeth_Zhang.pdf","date_updated":"2021-04-19T08:30:22Z","file_size":6924738,"creator":"dernst","file_id":"9339","checksum":"2a5800d91b96d08b525e17319dcd5e44","success":1,"content_type":"application/pdf","access_level":"open_access","relation":"main_file"}],"language":[{"iso":"eng"}],"scopus_import":"1","month":"03","intvolume":" 357","abstract":[{"text":"Background: To understand information coding in single neurons, it is necessary to analyze subthreshold synaptic events, action potentials (APs), and their interrelation in different behavioral states. However, detecting excitatory postsynaptic potentials (EPSPs) or currents (EPSCs) in behaving animals remains challenging, because of unfavorable signal-to-noise ratio, high frequency, fluctuating amplitude, and variable time course of synaptic events.\r\nNew method: We developed a method for synaptic event detection, termed MOD (Machine-learning Optimal-filtering Detection-procedure), which combines concepts of supervised machine learning and optimal Wiener filtering. Experts were asked to manually score short epochs of data. The algorithm was trained to obtain the optimal filter coefficients of a Wiener filter and the optimal detection threshold. Scored and unscored data were then processed with the optimal filter, and events were detected as peaks above threshold.\r\nResults: We challenged MOD with EPSP traces in vivo in mice during spatial navigation and EPSC traces in vitro in slices under conditions of enhanced transmitter release. The area under the curve (AUC) of the receiver operating characteristics (ROC) curve was, on average, 0.894 for in vivo and 0.969 for in vitro data sets, indicating high detection accuracy and efficiency.\r\nComparison with existing methods: When benchmarked using a (1 − AUC)−1 metric, MOD outperformed previous methods (template-fit, deconvolution, and Bayesian methods) by an average factor of 3.13 for in vivo data sets, but showed comparable (template-fit, deconvolution) or higher (Bayesian) computational efficacy.\r\nConclusions: MOD may become an important new tool for large-scale, real-time analysis of synaptic activity.","lang":"eng"}],"acknowledged_ssus":[{"_id":"SSU"}],"oa_version":"Published Version","file_date_updated":"2021-04-19T08:30:22Z","department":[{"_id":"PeJo"},{"_id":"ScienComp"}],"date_updated":"2023-08-07T14:36:14Z","ddc":["570"],"article_type":"original","type":"journal_article","tmp":{"short":"CC BY-NC-ND (4.0)","name":"Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International (CC BY-NC-ND 4.0)","legal_code_url":"https://creativecommons.org/licenses/by-nc-nd/4.0/legalcode","image":"/images/cc_by_nc_nd.png"},"status":"public","_id":"9329"},{"user_id":"4359f0d1-fa6c-11eb-b949-802e58b17ae8","citation":{"ama":"Petridou N, Corominas-Murtra B, Heisenberg C-PJ, Hannezo EB. Rigidity percolation uncovers a structural basis for embryonic tissue phase transitions. Cell. 2021;184(7):1914-1928.e19. doi:10.1016/j.cell.2021.02.017","apa":"Petridou, N., Corominas-Murtra, B., Heisenberg, C.-P. J., & Hannezo, E. B. (2021). Rigidity percolation uncovers a structural basis for embryonic tissue phase transitions. Cell. Elsevier. https://doi.org/10.1016/j.cell.2021.02.017","short":"N. Petridou, B. Corominas-Murtra, C.-P.J. Heisenberg, E.B. Hannezo, Cell 184 (2021) 1914–1928.e19.","ieee":"N. Petridou, B. Corominas-Murtra, C.-P. J. Heisenberg, and E. B. Hannezo, “Rigidity percolation uncovers a structural basis for embryonic tissue phase transitions,” Cell, vol. 184, no. 7. Elsevier, p. 1914–1928.e19, 2021.","mla":"Petridou, Nicoletta, et al. “Rigidity Percolation Uncovers a Structural Basis for Embryonic Tissue Phase Transitions.” Cell, vol. 184, no. 7, Elsevier, 2021, p. 1914–1928.e19, doi:10.1016/j.cell.2021.02.017.","ista":"Petridou N, Corominas-Murtra B, Heisenberg C-PJ, Hannezo EB. 2021. Rigidity percolation uncovers a structural basis for embryonic tissue phase transitions. Cell. 184(7), 1914–1928.e19.","chicago":"Petridou, Nicoletta, Bernat Corominas-Murtra, Carl-Philipp J Heisenberg, and Edouard B Hannezo. “Rigidity Percolation Uncovers a Structural Basis for Embryonic Tissue Phase Transitions.” Cell. Elsevier, 2021. https://doi.org/10.1016/j.cell.2021.02.017."},"title":"Rigidity percolation uncovers a structural basis for embryonic tissue phase transitions","author":[{"first_name":"Nicoletta","id":"2A003F6C-F248-11E8-B48F-1D18A9856A87","last_name":"Petridou","orcid":"0000-0002-8451-1195","full_name":"Petridou, Nicoletta"},{"full_name":"Corominas-Murtra, Bernat","orcid":"0000-0001-9806-5643","last_name":"Corominas-Murtra","first_name":"Bernat","id":"43BE2298-F248-11E8-B48F-1D18A9856A87"},{"id":"39427864-F248-11E8-B48F-1D18A9856A87","first_name":"Carl-Philipp J","full_name":"Heisenberg, Carl-Philipp J","orcid":"0000-0002-0912-4566","last_name":"Heisenberg"},{"last_name":"Hannezo","full_name":"Hannezo, Edouard B","orcid":"0000-0001-6005-1561","first_name":"Edouard B","id":"3A9DB764-F248-11E8-B48F-1D18A9856A87"}],"article_processing_charge":"No","external_id":{"isi":["000636734000022"],"pmid":["33730596"]},"project":[{"grant_number":"742573","name":"Interaction and feedback between cell mechanics and fate specification in vertebrate gastrulation","_id":"260F1432-B435-11E9-9278-68D0E5697425","call_identifier":"H2020"},{"grant_number":"851288","name":"Design Principles of Branching Morphogenesis","_id":"05943252-7A3F-11EA-A408-12923DDC885E","call_identifier":"H2020"},{"name":"Tissue material properties in embryonic development","grant_number":"V00736","call_identifier":"FWF","_id":"2693FD8C-B435-11E9-9278-68D0E5697425"}],"day":"01","publication":"Cell","isi":1,"has_accepted_license":"1","year":"2021","doi":"10.1016/j.cell.2021.02.017","date_published":"2021-04-01T00:00:00Z","date_created":"2021-04-11T22:01:14Z","page":"1914-1928.e19","acknowledgement":"We thank Carl Goodrich and the members of the Heisenberg and Hannezo groups, in particular Reka Korei, for help, technical advice, and discussions; and the Bioimaging and zebrafish facilities of the IST Austria for continuous support. This work was supported by the Elise Richter Program of Austrian Science Fund (FWF) to N.I.P. ( V 736-B26 ) and the European Union (European Research Council Advanced Grant 742573 to C.-P.H. and European Research Council Starting Grant 851288 to E.H.).","quality_controlled":"1","publisher":"Elsevier","oa":1,"ddc":["570"],"date_updated":"2023-08-07T14:33:59Z","department":[{"_id":"CaHe"},{"_id":"EdHa"}],"file_date_updated":"2021-06-08T10:04:10Z","_id":"9316","status":"public","article_type":"original","type":"journal_article","tmp":{"legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode","image":"/images/cc_by.png","name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)","short":"CC BY (4.0)"},"file":[{"content_type":"application/pdf","access_level":"open_access","relation":"main_file","checksum":"1e5295fbd9c2a459173ec45a0e8a7c2e","file_id":"9534","success":1,"date_updated":"2021-06-08T10:04:10Z","file_size":11405875,"creator":"cziletti","date_created":"2021-06-08T10:04:10Z","file_name":"2021_Cell_Petridou.pdf"}],"language":[{"iso":"eng"}],"publication_identifier":{"issn":["00928674"],"eissn":["10974172"]},"publication_status":"published","related_material":{"link":[{"url":"https://ist.ac.at/en/news/embryonic-tissue-undergoes-phase-transition/","relation":"press_release","description":"News on IST Homepage"}]},"issue":"7","volume":184,"ec_funded":1,"oa_version":"Published Version","pmid":1,"acknowledged_ssus":[{"_id":"Bio"},{"_id":"PreCl"}],"abstract":[{"text":"Embryo morphogenesis is impacted by dynamic changes in tissue material properties, which have been proposed to occur via processes akin to phase transitions (PTs). Here, we show that rigidity percolation provides a simple and robust theoretical framework to predict material/structural PTs of embryonic tissues from local cell connectivity. By using percolation theory, combined with directly monitoring dynamic changes in tissue rheology and cell contact mechanics, we demonstrate that the zebrafish blastoderm undergoes a genuine rigidity PT, brought about by a small reduction in adhesion-dependent cell connectivity below a critical value. We quantitatively predict and experimentally verify hallmarks of PTs, including power-law exponents and associated discontinuities of macroscopic observables. Finally, we show that this uniform PT depends on blastoderm cells undergoing meta-synchronous divisions causing random and, consequently, uniform changes in cell connectivity. Collectively, our theoretical and experimental findings reveal the structural basis of material PTs in an organismal context.","lang":"eng"}],"month":"04","intvolume":" 184","scopus_import":"1"},{"_id":"9317","tmp":{"legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode","image":"/images/cc_by.png","name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)","short":"CC BY (4.0)"},"type":"journal_article","article_type":"original","status":"public","date_updated":"2023-08-07T14:35:44Z","ddc":["516"],"department":[{"_id":"HeEd"}],"file_date_updated":"2021-12-01T10:56:53Z","abstract":[{"text":"Given a locally finite X⊆Rd and a radius r≥0, the k-fold cover of X and r consists of all points in Rd that have k or more points of X within distance r. We consider two filtrations—one in scale obtained by fixing k and increasing r, and the other in depth obtained by fixing r and decreasing k—and we compute the persistence diagrams of both. While standard methods suffice for the filtration in scale, we need novel geometric and topological concepts for the filtration in depth. In particular, we introduce a rhomboid tiling in Rd+1 whose horizontal integer slices are the order-k Delaunay mosaics of X, and construct a zigzag module of Delaunay mosaics that is isomorphic to the persistence module of the multi-covers.","lang":"eng"}],"oa_version":"Published Version","scopus_import":"1","intvolume":" 65","month":"03","publication_status":"published","publication_identifier":{"eissn":["1432-0444"],"issn":["0179-5376"]},"language":[{"iso":"eng"}],"file":[{"success":1,"checksum":"59b4e1e827e494209bcb4aae22e1d347","file_id":"10394","content_type":"application/pdf","relation":"main_file","access_level":"open_access","file_name":"2021_DisCompGeo_Edelsbrunner_Osang.pdf","date_created":"2021-12-01T10:56:53Z","file_size":677704,"date_updated":"2021-12-01T10:56:53Z","creator":"cchlebak"}],"ec_funded":1,"related_material":{"record":[{"relation":"earlier_version","id":"187","status":"public"}]},"volume":65,"project":[{"grant_number":"788183","name":"Alpha Shape Theory Extended","_id":"266A2E9E-B435-11E9-9278-68D0E5697425","call_identifier":"H2020"},{"grant_number":"I02979-N35","name":"Persistence and stability of geometric complexes","_id":"2561EBF4-B435-11E9-9278-68D0E5697425","call_identifier":"FWF"}],"citation":{"short":"H. Edelsbrunner, G.F. Osang, Discrete and Computational Geometry 65 (2021) 1296–1313.","ieee":"H. Edelsbrunner and G. F. Osang, “The multi-cover persistence of Euclidean balls,” Discrete and Computational Geometry, vol. 65. Springer Nature, pp. 1296–1313, 2021.","ama":"Edelsbrunner H, Osang GF. The multi-cover persistence of Euclidean balls. Discrete and Computational Geometry. 2021;65:1296–1313. doi:10.1007/s00454-021-00281-9","apa":"Edelsbrunner, H., & Osang, G. F. (2021). The multi-cover persistence of Euclidean balls. Discrete and Computational Geometry. Springer Nature. https://doi.org/10.1007/s00454-021-00281-9","mla":"Edelsbrunner, Herbert, and Georg F. Osang. “The Multi-Cover Persistence of Euclidean Balls.” Discrete and Computational Geometry, vol. 65, Springer Nature, 2021, pp. 1296–1313, doi:10.1007/s00454-021-00281-9.","ista":"Edelsbrunner H, Osang GF. 2021. The multi-cover persistence of Euclidean balls. Discrete and Computational Geometry. 65, 1296–1313.","chicago":"Edelsbrunner, Herbert, and Georg F Osang. “The Multi-Cover Persistence of Euclidean Balls.” Discrete and Computational Geometry. Springer Nature, 2021. https://doi.org/10.1007/s00454-021-00281-9."},"user_id":"4359f0d1-fa6c-11eb-b949-802e58b17ae8","article_processing_charge":"Yes (via OA deal)","external_id":{"isi":["000635460400001"]},"author":[{"orcid":"0000-0002-9823-6833","full_name":"Edelsbrunner, Herbert","last_name":"Edelsbrunner","first_name":"Herbert","id":"3FB178DA-F248-11E8-B48F-1D18A9856A87"},{"last_name":"Osang","full_name":"Osang, Georg F","first_name":"Georg F","id":"464B40D6-F248-11E8-B48F-1D18A9856A87"}],"title":"The multi-cover persistence of Euclidean balls","acknowledgement":"This project has received funding from the European Research Council (ERC) under the European Union’s Horizon 2020 research and innovation programme (Grant Agreement No. 78818 Alpha), and by the DFG Collaborative Research Center TRR 109, ‘Discretization in Geometry and Dynamics’, through Grant No. I02979-N35 of the Austrian Science Fund (FWF)\r\nOpen Access funding provided by the Institute of Science and Technology (IST Austria).","oa":1,"quality_controlled":"1","publisher":"Springer Nature","year":"2021","isi":1,"has_accepted_license":"1","publication":"Discrete and Computational Geometry","day":"31","page":"1296–1313","date_created":"2021-04-11T22:01:15Z","date_published":"2021-03-31T00:00:00Z","doi":"10.1007/s00454-021-00281-9"},{"article_number":"e28","project":[{"grant_number":"754411","name":"ISTplus - Postdoctoral Fellowships","call_identifier":"H2020","_id":"260C2330-B435-11E9-9278-68D0E5697425"},{"call_identifier":"H2020","_id":"25C6DC12-B435-11E9-9278-68D0E5697425","grant_number":"694227","name":"Analysis of quantum many-body systems"}],"citation":{"chicago":"Bossmann, Lea, Sören P Petrat, and Robert Seiringer. “Asymptotic Expansion of Low-Energy Excitations for Weakly Interacting Bosons.” Forum of Mathematics, Sigma. Cambridge University Press, 2021. https://doi.org/10.1017/fms.2021.22.","ista":"Bossmann L, Petrat SP, Seiringer R. 2021. Asymptotic expansion of low-energy excitations for weakly interacting bosons. Forum of Mathematics, Sigma. 9, e28.","mla":"Bossmann, Lea, et al. “Asymptotic Expansion of Low-Energy Excitations for Weakly Interacting Bosons.” Forum of Mathematics, Sigma, vol. 9, e28, Cambridge University Press, 2021, doi:10.1017/fms.2021.22.","ama":"Bossmann L, Petrat SP, Seiringer R. Asymptotic expansion of low-energy excitations for weakly interacting bosons. Forum of Mathematics, Sigma. 2021;9. doi:10.1017/fms.2021.22","apa":"Bossmann, L., Petrat, S. P., & Seiringer, R. (2021). Asymptotic expansion of low-energy excitations for weakly interacting bosons. Forum of Mathematics, Sigma. Cambridge University Press. https://doi.org/10.1017/fms.2021.22","short":"L. Bossmann, S.P. Petrat, R. Seiringer, Forum of Mathematics, Sigma 9 (2021).","ieee":"L. Bossmann, S. P. Petrat, and R. Seiringer, “Asymptotic expansion of low-energy excitations for weakly interacting bosons,” Forum of Mathematics, Sigma, vol. 9. Cambridge University Press, 2021."},"user_id":"4359f0d1-fa6c-11eb-b949-802e58b17ae8","author":[{"id":"A2E3BCBE-5FCC-11E9-AA4B-76F3E5697425","first_name":"Lea","last_name":"Bossmann","orcid":"0000-0002-6854-1343","full_name":"Bossmann, Lea"},{"first_name":"Sören P","id":"40AC02DC-F248-11E8-B48F-1D18A9856A87","last_name":"Petrat","orcid":"0000-0002-9166-5889","full_name":"Petrat, Sören P"},{"orcid":"0000-0002-6781-0521","full_name":"Seiringer, Robert","last_name":"Seiringer","first_name":"Robert","id":"4AFD0470-F248-11E8-B48F-1D18A9856A87"}],"article_processing_charge":"Yes (via OA deal)","external_id":{"isi":["000634006900001"]},"title":"Asymptotic expansion of low-energy excitations for weakly interacting bosons","acknowledgement":"The first author gratefully acknowledges funding from the European Union’s Horizon 2020 research and innovation programme under Marie Skłodowska-Curie Grant Agreement No. 754411. The third author was supported by the European Research Council (ERC) under the European Union’s Horizon 2020 research and innovation programme (Grant Agreement No. 694227).","quality_controlled":"1","publisher":"Cambridge University Press","oa":1,"has_accepted_license":"1","isi":1,"year":"2021","day":"26","publication":"Forum of Mathematics, Sigma","date_published":"2021-03-26T00:00:00Z","doi":"10.1017/fms.2021.22","date_created":"2021-04-11T22:01:15Z","_id":"9318","article_type":"original","type":"journal_article","tmp":{"legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode","image":"/images/cc_by.png","name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)","short":"CC BY (4.0)"},"status":"public","date_updated":"2023-08-07T14:35:06Z","ddc":["510"],"department":[{"_id":"RoSe"}],"file_date_updated":"2021-04-12T07:15:58Z","abstract":[{"lang":"eng","text":"We consider a system of N bosons in the mean-field scaling regime for a class of interactions including the repulsive Coulomb potential. We derive an asymptotic expansion of the low-energy eigenstates and the corresponding energies, which provides corrections to Bogoliubov theory to any order in 1/N."}],"oa_version":"Published Version","scopus_import":"1","month":"03","intvolume":" 9","publication_identifier":{"eissn":["20505094"]},"publication_status":"published","file":[{"creator":"dernst","file_size":883851,"date_updated":"2021-04-12T07:15:58Z","file_name":"2021_ForumMath_Bossmann.pdf","date_created":"2021-04-12T07:15:58Z","relation":"main_file","access_level":"open_access","content_type":"application/pdf","success":1,"file_id":"9319","checksum":"17a3e6786d1e930cf0c14a880a6d7e92"}],"language":[{"iso":"eng"}],"volume":9,"ec_funded":1},{"doi":"10.1063/5.0050235","date_published":"2021-04-07T00:00:00Z","date_created":"2021-04-18T22:01:40Z","day":"07","publication":"Applied Physics Letters","isi":1,"year":"2021","quality_controlled":"1","publisher":"AIP Publishing","oa":1,"acknowledgement":"We acknowledge fruitful discussions with John Close, Chris Freier, Kyle Hardman, Joseph Hope, and Paul Wigley, and insightful suggestions made by Franck Pereira dos Santos on behalf of the Atom Interferometry and Inertial Sensors team at SYRTE. S.S.S. was supported by an Australian Research Council Discovery Early Career Researcher Award (DECRA), Project No. DE200100495. O.H. was supported by IST Austria.","title":"Improving cold-atom sensors with quantum entanglement: Prospects and challenges","author":[{"first_name":"Stuart S.","last_name":"Szigeti","full_name":"Szigeti, Stuart S."},{"full_name":"Hosten, Onur","orcid":"0000-0002-2031-204X","last_name":"Hosten","id":"4C02D85E-F248-11E8-B48F-1D18A9856A87","first_name":"Onur"},{"first_name":"Simon A.","last_name":"Haine","full_name":"Haine, Simon A."}],"external_id":{"arxiv":["2010.09168"],"isi":["000637702100001"]},"article_processing_charge":"No","user_id":"4359f0d1-fa6c-11eb-b949-802e58b17ae8","citation":{"ista":"Szigeti SS, Hosten O, Haine SA. 2021. Improving cold-atom sensors with quantum entanglement: Prospects and challenges. Applied Physics Letters. 118(14), 140501.","chicago":"Szigeti, Stuart S., Onur Hosten, and Simon A. Haine. “Improving Cold-Atom Sensors with Quantum Entanglement: Prospects and Challenges.” Applied Physics Letters. AIP Publishing, 2021. https://doi.org/10.1063/5.0050235.","ama":"Szigeti SS, Hosten O, Haine SA. Improving cold-atom sensors with quantum entanglement: Prospects and challenges. Applied Physics Letters. 2021;118(14). doi:10.1063/5.0050235","apa":"Szigeti, S. S., Hosten, O., & Haine, S. A. (2021). Improving cold-atom sensors with quantum entanglement: Prospects and challenges. Applied Physics Letters. AIP Publishing. https://doi.org/10.1063/5.0050235","ieee":"S. S. Szigeti, O. Hosten, and S. A. Haine, “Improving cold-atom sensors with quantum entanglement: Prospects and challenges,” Applied Physics Letters, vol. 118, no. 14. AIP Publishing, 2021.","short":"S.S. Szigeti, O. Hosten, S.A. Haine, Applied Physics Letters 118 (2021).","mla":"Szigeti, Stuart S., et al. “Improving Cold-Atom Sensors with Quantum Entanglement: Prospects and Challenges.” Applied Physics Letters, vol. 118, no. 14, 140501, AIP Publishing, 2021, doi:10.1063/5.0050235."},"article_number":"140501","issue":"14","volume":118,"language":[{"iso":"eng"}],"publication_identifier":{"issn":["00036951"]},"publication_status":"published","month":"04","intvolume":" 118","scopus_import":"1","main_file_link":[{"open_access":"1","url":"https://arxiv.org/abs/2010.09168"}],"oa_version":"Preprint","abstract":[{"text":"Quantum entanglement has been generated and verified in cold-atom experiments and used to make atom-interferometric measurements below the shot-noise limit. However, current state-of-the-art cold-atom devices exploit separable (i.e., unentangled) atomic states. This perspective piece asks the question: can entanglement usefully improve cold-atom sensors, in the sense that it gives new sensing capabilities unachievable with current state-of-the-art devices? We briefly review the state-of-the-art in precision cold-atom sensing, focusing on clocks and inertial sensors, identifying the potential benefits entanglement could bring to these devices, and the challenges that need to be overcome to realize these benefits. We survey demonstrated methods of generating metrologically useful entanglement in cold-atom systems, note their relative strengths and weaknesses, and assess their prospects for near-to-medium term quantum-enhanced cold-atom sensing.","lang":"eng"}],"department":[{"_id":"OnHo"}],"date_updated":"2023-08-07T14:36:42Z","status":"public","article_type":"original","type":"journal_article","_id":"9331"},{"scopus_import":"1","month":"04","intvolume":" 118","acknowledged_ssus":[{"_id":"EM-Fac"}],"abstract":[{"text":"In nerve cells the genes encoding for α2δ subunits of voltage-gated calcium channels have been linked to synaptic functions and neurological disease. Here we show that α2δ subunits are essential for the formation and organization of glutamatergic synapses. Using a cellular α2δ subunit triple-knockout/knockdown model, we demonstrate a failure in presynaptic differentiation evidenced by defective presynaptic calcium channel clustering and calcium influx, smaller presynaptic active zones, and a strongly reduced accumulation of presynaptic vesicle-associated proteins (synapsin and vGLUT). The presynaptic defect is associated with the downscaling of postsynaptic AMPA receptors and the postsynaptic density. The role of α2δ isoforms as synaptic organizers is highly redundant, as each individual α2δ isoform can rescue presynaptic calcium channel trafficking and expression of synaptic proteins. Moreover, α2δ-2 and α2δ-3 with mutated metal ion-dependent adhesion sites can fully rescue presynaptic synapsin expression but only partially calcium channel trafficking, suggesting that the regulatory role of α2δ subunits is independent from its role as a calcium channel subunit. Our findings influence the current view on excitatory synapse formation. First, our study suggests that postsynaptic differentiation is secondary to presynaptic differentiation. Second, the dependence of presynaptic differentiation on α2δ implicates α2δ subunits as potential nucleation points for the organization of synapses. Finally, our results suggest that α2δ subunits act as transsynaptic organizers of glutamatergic synapses, thereby aligning the synaptic active zone with the postsynaptic density.","lang":"eng"}],"oa_version":"Published Version","volume":118,"issue":"14","ec_funded":1,"publication_identifier":{"eissn":["1091-6490"]},"publication_status":"published","file":[{"success":1,"checksum":"dd014f68ae9d7d8d8fc4139a24e04506","file_id":"9340","relation":"main_file","access_level":"open_access","content_type":"application/pdf","file_name":"2021_PNAS_Schoepf.pdf","date_created":"2021-04-19T10:10:56Z","creator":"dernst","file_size":2603911,"date_updated":"2021-04-19T10:10:56Z"}],"language":[{"iso":"eng"}],"type":"journal_article","article_type":"original","tmp":{"legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode","image":"/images/cc_by.png","name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)","short":"CC BY (4.0)"},"status":"public","_id":"9330","department":[{"_id":"EM-Fac"},{"_id":"RySh"}],"file_date_updated":"2021-04-19T10:10:56Z","date_updated":"2023-08-08T13:08:47Z","ddc":["570"],"quality_controlled":"1","publisher":"National Academy of Sciences","oa":1,"acknowledgement":"We thank Arnold Schwartz for providing α2δ-1 knockout mice; Ariane Benedetti, Sabine Baumgartner, Sandra Demetz, and Irene Mahlknecht for technical support; Nadine Ortner and Andreas Lieb for electrophysiological experiments; the team of the Electron Microscopy Facility at the Institute of Science and Technology Austria for technical support related to ultrastructural analysis; Hermann Dietrich and Anja Beierfuß and her team for animal care; Jutta Engel and Jörg Striessnig for critical discussions; and Bruno Benedetti and Bernhard Flucher for critical discussions and reading the manuscript. This study was supported by Austrian Science Fund Grants P24079, F44060, F44150, and DOC30-B30 (to G.J.O.) and T855 (to M.C.), European Research Council Grant AdG 694539 (to R.S.), Deutsche Forschungsgemeinschaft\r\nGrant SFB1348-TP A03 (to M.M.), and Interdisziplinäre Zentrum für Klinische Forschung Münster Grant Mi3/004/19 (to M.M.). This work is part of the PhD theses of C.L.S., S.M.G., and C.A.","date_published":"2021-04-06T00:00:00Z","doi":"10.1073/pnas.1920827118","date_created":"2021-04-18T22:01:40Z","isi":1,"has_accepted_license":"1","year":"2021","day":"06","publication":"PNAS","project":[{"grant_number":"694539","name":"In situ analysis of single channel subunit composition in neurons: physiological implication in synaptic plasticity and behaviour","call_identifier":"H2020","_id":"25CA28EA-B435-11E9-9278-68D0E5697425"}],"author":[{"full_name":"Schöpf, Clemens L.","last_name":"Schöpf","first_name":"Clemens L."},{"first_name":"Cornelia","full_name":"Ablinger, Cornelia","last_name":"Ablinger"},{"last_name":"Geisler","full_name":"Geisler, Stefanie M.","first_name":"Stefanie M."},{"full_name":"Stanika, Ruslan I.","last_name":"Stanika","first_name":"Ruslan I."},{"last_name":"Campiglio","full_name":"Campiglio, Marta","first_name":"Marta"},{"id":"3F99E422-F248-11E8-B48F-1D18A9856A87","first_name":"Walter","full_name":"Kaufmann, Walter","orcid":"0000-0001-9735-5315","last_name":"Kaufmann"},{"first_name":"Benedikt","last_name":"Nimmervoll","full_name":"Nimmervoll, Benedikt"},{"first_name":"Bettina","full_name":"Schlick, Bettina","last_name":"Schlick"},{"first_name":"Johannes","full_name":"Brockhaus, Johannes","last_name":"Brockhaus"},{"full_name":"Missler, Markus","last_name":"Missler","first_name":"Markus"},{"id":"499F3ABC-F248-11E8-B48F-1D18A9856A87","first_name":"Ryuichi","full_name":"Shigemoto, Ryuichi","orcid":"0000-0001-8761-9444","last_name":"Shigemoto"},{"first_name":"Gerald J.","last_name":"Obermair","full_name":"Obermair, Gerald J."}],"external_id":{"isi":["000637398300002"]},"article_processing_charge":"No","title":"Presynaptic α2δ subunits are key organizers of glutamatergic synapses","citation":{"chicago":"Schöpf, Clemens L., Cornelia Ablinger, Stefanie M. Geisler, Ruslan I. Stanika, Marta Campiglio, Walter Kaufmann, Benedikt Nimmervoll, et al. “Presynaptic Α2δ Subunits Are Key Organizers of Glutamatergic Synapses.” PNAS. National Academy of Sciences, 2021. https://doi.org/10.1073/pnas.1920827118.","ista":"Schöpf CL, Ablinger C, Geisler SM, Stanika RI, Campiglio M, Kaufmann W, Nimmervoll B, Schlick B, Brockhaus J, Missler M, Shigemoto R, Obermair GJ. 2021. Presynaptic α2δ subunits are key organizers of glutamatergic synapses. PNAS. 118(14).","mla":"Schöpf, Clemens L., et al. “Presynaptic Α2δ Subunits Are Key Organizers of Glutamatergic Synapses.” PNAS, vol. 118, no. 14, National Academy of Sciences, 2021, doi:10.1073/pnas.1920827118.","short":"C.L. Schöpf, C. Ablinger, S.M. Geisler, R.I. Stanika, M. Campiglio, W. Kaufmann, B. Nimmervoll, B. Schlick, J. Brockhaus, M. Missler, R. Shigemoto, G.J. Obermair, PNAS 118 (2021).","ieee":"C. L. Schöpf et al., “Presynaptic α2δ subunits are key organizers of glutamatergic synapses,” PNAS, vol. 118, no. 14. National Academy of Sciences, 2021.","apa":"Schöpf, C. L., Ablinger, C., Geisler, S. M., Stanika, R. I., Campiglio, M., Kaufmann, W., … Obermair, G. J. (2021). Presynaptic α2δ subunits are key organizers of glutamatergic synapses. PNAS. National Academy of Sciences. https://doi.org/10.1073/pnas.1920827118","ama":"Schöpf CL, Ablinger C, Geisler SM, et al. Presynaptic α2δ subunits are key organizers of glutamatergic synapses. PNAS. 2021;118(14). doi:10.1073/pnas.1920827118"},"user_id":"4359f0d1-fa6c-11eb-b949-802e58b17ae8"}]