@article{847,
abstract = {The accumulation of genome-wide information on single nucleotide polymorphisms in humans provides an unprecedented opportunity to detect the evolutionary forces responsible for heterogeneity of the level of genetic variability across loci. Previous studies have shown that history of recombination events has produced long haplotype blocks in the human genome, which contribute to this heterogeneity. Other factors, however, such as natural selection or the heterogeneity of mutation rates across loci, may also lead to heterogeneity of genetic variability. We compared synonymous and non-synonymous variability within human genes with their divergence from murine orthologs. We separately analyzed the non-synonymous variants predicted to damage protein structure or function and the variants predicted to be functionally benign. The predictions were based on comparative sequence analysis and, in some cases, on the analysis of protein structure. A strong correlation between non-synonymous, benign variability and non-synonymous human-mouse divergence suggests that selection played an important role in shaping the pattern of variability in coding regions of human genes. However, the lack of correlation between deleterious variability and evolutionary divergence shows that a substantial proportion of the observed non-synonymous single-nucleotide polymorphisms reduces fitness and never reaches fixation. Evolutionary and medical implications of the impact of selection on human polymorphisms are discussed.},
author = {Sunyaev, Shamil R and Fyodor Kondrashov and Bork, Peer and Ramensky, Vasily},
journal = {Human Molecular Genetics},
number = {24},
pages = {3325 -- 3330},
publisher = {Oxford University Press},
title = {{Impact of selection, mutation rate and genetic drift on human genetic variation}},
doi = {10.1093/hmg/ddg359},
volume = {12},
year = {2003},
}
@article{876,
abstract = {Alternative splicing is thought to be a major source of functional diversity in animal proteins. We analyzed the evolutionary conservation of proteins encoded by alternatively spliced genes and predicted the ancestral state for 73 cases of alternative splicing (25 insertions and 48 deletions). The amino acid sequences of most of the inserts in proteins produced by alternative splicing are as conserved as the surrounding sequences. Thus, alternative splicing often creates novel isoforms by the insertion of new, functional protein sequences that probably originated from noncoding sequences of introns.},
author = {Fyodor Kondrashov and Koonin, Eugene V},
journal = {Trends in Genetics},
number = {3},
pages = {115 -- 119},
publisher = {Elsevier},
title = {{Evolution of alternative splicing: Deletions, insertions and origin of functional parts of proteins from intron sequences}},
doi = {10.1016/S0168-9525(02)00029-X},
volume = {19},
year = {2003},
}
@article{1457,
abstract = {Among the major mathematical approaches to mirror symmetry are those of Batyrev-Borisov and Stromdnger-Yau-Zaslow (SYZ). The first is explicit and amenable to computation but is not clearly related to the physical motivation; the second is the opposite. Furthermore, it is far from obvious that mirror partners in one sense will also be mirror partners in the other. This paper concerns a class of examples that can be shown to satisfy the requirements of SYZ, but whose Hodge numbers are also equal. This provides significant evidence in support of SYZ. Moreover, the examples are of great interest in their own right: they are spaces of flat SLr-connections on a smooth curve. The mirror is the corresponding space for the Langlands dual group PGLr. These examples therefore throw a bridge from mirror symmetry to the duality theory of Lie groups and, more broadly, to the geometric Langlands program.},
author = {Tamas Hausel and Thaddeus, Michael},
journal = {Inventiones Mathematicae},
number = {1},
pages = {197 -- 229},
publisher = {Springer},
title = {{Mirror symmetry, langlands duality, and the Hitchin system}},
doi = {10.1007/s00222-003-0286-7},
volume = {153},
year = {2003},
}
@article{1458,
abstract = {The moduli space of stable bundles of rank $2$ and degree $1$ on a Riemann surface has rational cohomology generated by the so-called universal classes. The work of Baranovsky, King-Newstead, Siebert-Tian and Zagier provided a complete set of relations between these classes, expressed in terms of a recursion in the genus. This paper accomplishes the same thing for the noncompact moduli spaces of Higgs bundles, in the sense of Hitchin and Simpson. There are many more independent relations than for stable bundles, but in a sense the answer is simpler, since the formulas are completely explicit, not recursive. The results of Kirwan on equivariant cohomology for holomorphic circle actions are of key importance.},
author = {Tamas Hausel and Thaddeus, Michael},
journal = {Journal of the American Mathematical Society},
number = {2},
pages = {303 -- 329},
publisher = {American Mathematical Society},
title = {{Relations in the cohomology ring of the moduli space of rank 2 Higgs bundles}},
doi = {10.1090/S0894-0347-02-00417-4},
volume = {16},
year = {2003},
}
@article{1459,
abstract = {In this paper we explicitly calculate the analogue of the 't Hooft SU (2) Yang-Mills instantons on Gibbons-Hawking multi-centered gravitational instantons, which come in two parallel families: the multi-Eguchi-Hanson, or Ak ALE gravitational instantons and the multi-Taub-NUT spaces, or Ak ALF gravitational instantons. We calculate their energy and find the reducible ones. Following Kronheimer we also exploit the U(1) invariance of our solutions and study the corresponding explicit singular SU (2) magnetic monopole solutions of the Bogomolny equations on flat ℝ3.},
author = {Etesi, Gábor and Tamas Hausel},
journal = {Communications in Mathematical Physics},
number = {2},
pages = {275 -- 288},
publisher = {Springer},
title = {{On Yang-Mills instantons over multi-centered gravitational instantons}},
doi = {10.1007/s00220-003-0806-8},
volume = {235},
year = {2003},
}
@inproceedings{3170,
abstract = {Geodesic active contours and graph cuts are two standard image segmentation techniques. We introduce a new segmentation method combining some of their benefits. Our main intuition is that any cut on a graph embedded in some continuous space can be interpreted as a contour (in 2D) or a surface (in 3D). We show how to build a grid graph and set its edge weights so that the cost of cuts is arbitrarily close to the length (area) of the corresponding contours (surfaces) for any anisotropic Riemannian metric. There are two interesting consequences of this technical result. First, graph cut algorithms can be used to find globally minimum geodesic contours (minimal surfaces in 3D) under arbitrary Riemannian metric for a given set of boundary conditions. Second, we show how to minimize metrication artifacts in existing graph-cut based methods in vision. Theoretically speaking, our work provides an interesting link between several branches of mathematics -differential geometry, integral geometry, and combinatorial optimization. The main technical problem is solved using Cauchy-Crofton formula from integral geometry.},
author = {Boykov, Yuri and Vladimir Kolmogorov},
pages = {26 -- 33},
publisher = {IEEE},
title = {{Computing geodesics and minimal surfaces via graph cuts}},
doi = {10.1109/ICCV.2003.1238310},
volume = {1},
year = {2003},
}
@inproceedings{3171,
abstract = {Reconstructing a 3-D scene from more than one camera is a classical problem in computer vision. One of the major sources of difficulty is the fact that not all scene elements are visible from all cameras. In the last few years, two promising approaches have been developed 11,12 that formulate the scene reconstruction problem in terms of energy minimization, and minimize the energy using graph cuts. These energy minimization approaches treat the input images symmetrically, handle visibility constraints correctly, and allow spatial smoothness to be enforced. However, these algorithm propose different problem formulations, and handle a limited class of smoothness terms. One algorithm 11 uses a problem formulation that is restricted to two-camera stereo, and imposes smoothness between a pair of cameras. The other algorithm 12 can handle an arbitrary number of cameras, but imposes smoothness only with respect to a single camera. In this paper we give a more general energy minimization formulation for the problem, which allows a larger class of spatial smoothness constraints. We show that our formulation includes both of the previous approaches as special cases, as well as permitting new energy functions. Experimental results on real data with ground truth are also included. },
author = {Vladimir Kolmogorov and Zabih, Ramin and Gortler, Steven},
pages = {501 -- 516},
publisher = {Springer},
title = {{Generalized multi camera scene reconstruction using graph cuts}},
doi = {10.1007/978-3-540-45063-4_32},
volume = {2683},
year = {2003},
}
@inproceedings{3174,
abstract = {We address visual correspondence problems without assuming that scene points have similar intensities in different views. This situation is common, usually due to non-lambertian scenes or to differences between cameras. We use maximization of mutual information, a powerful technique for registering images that requires no a priori model of the relationship between scene intensities in different views. However, it has proven difficult to use mutual information to compute dense visual correspondence. Comparing fixed-size windows via mutual information suffers from the well-known problems of fixed windows, namely poor performance at discontinuities and in low-texture regions. In this paper, we show how to compute visual correspondence using mutual information without suffering from these problems. Using 'a simple approximation, mutual information can be incorporated into the standard energy minimization framework used in early vision. The energy can then be efficiently minimized using graph cuts, which preserve discontinuities and handle low-texture regions. The resulting algorithm combines the accurate disparity maps that come from graph cuts with the tolerance for intensity changes that comes from mutual information.},
author = {Kim, Junhwan and Vladimir Kolmogorov and Zabih, Ramin},
pages = {1033 -- 1040},
publisher = {IEEE},
title = {{Visual correspondence using energy minimization and mutual information}},
doi = {10.1109/ICCV.2003.1238463},
volume = {2},
year = {2003},
}
@article{3209,
abstract = {We show that the fixed alphabet shortest common supersequence (SCS) and the fixed alphabet longest common subsequence (LCS) problems parameterized in the number of strings are W[1]-hard. Unless W[1]=FPT, this rules out the existence of algorithms with time complexity of O(f(k)nα) for those problems. Here n is the size of the problem instance, α is constant, k is the number of strings and f is any function of k. The fixed alphabet version of the LCS problem is of particular interest considering the importance of sequence comparison (e.g. multiple sequence alignment) in the fixed length alphabet world of DNA and protein sequences.},
author = {Krzysztof Pietrzak},
journal = {Journal of Computer and System Sciences},
number = {4},
pages = {757 -- 771},
publisher = {Elsevier},
title = {{On the parameterized complexity of the fixed alphabet shortest common supersequence and longest common subsequence problems}},
doi = {10.1016/S0022-0000(03)00078-3},
volume = {67},
year = {2003},
}
@inproceedings{3210,
abstract = {Luby and Rackoff showed how to construct a (super-)pseudo-random permutation {0,1}2n→ {0,1}2n from some number r of pseudo-random functions {0,1}n → {0,1}n. Their construction, motivated by DES, consists of a cascade of r Feistel permutations. A Feistel permutation 1for a pseudo-random function f is defined as (L, R) → (R,L ⊕ f (R)), where L and R are the left and right part of the input and ⊕ denotes bitwise XOR or, in this paper, any other group operation on {0,1}n. The only non-trivial step of the security proof consists of proving that the cascade of r Feistel permutations with independent uniform random functions {0,1}n → {0,1}n, denoted Ψ2nr is indistinguishable from a uniform random permutation {0,1}2n → {0,1}2n by any computationally unbounded adaptive distinguisher making at most O(2cn) combined chosen plaintext/ciphertext queries for any c < α, where a is a security parameter. Luby and Rackoff proved α = 1/2 for r = 4. A natural problem, proposed by Pieprzyk is to improve on α for larger r. The best known result, α = 3/4 for r = 6, is due to Patarin. In this paper we prove a = 1 -O(1/r), i.e., the trivial upper bound α = 1 can be approached. The proof uses some new techniques that can be of independent interest. },
author = {Maurer, Ueli M and Krzysztof Pietrzak},
pages = {544 -- 561},
publisher = {Springer},
title = {{The security of many round Luby Rackoff pseudo random permutations}},
doi = {10.1007/3-540-39200-9_34},
volume = {2656},
year = {2003},
}
@inbook{3458,
author = {Peter Jonas and Unsicker, Klaus},
booktitle = {Lehrbuch Vorklinik},
editor = {Schmidt, R. F.},
pages = {3 -- 26},
publisher = {Deutscher Ärzte Verlag},
title = {{Molekulare und zelluläre Grundlagen des Nervensystems.}},
volume = {B},
year = {2003},
}
@article{3526,
abstract = {Neurons can produce action potentials with high temporal precision(1). A fundamental issue is whether, and how, this capability is used in information processing. According to the `cell assembly' hypothesis, transient synchrony of anatomically distributed groups of neurons underlies processing of both external sensory input and internal cognitive mechanisms(2-4). Accordingly, neuron populations should be arranged into groups whose synchrony exceeds that predicted by common modulation by sensory input. Here we find that the spike times of hippocampal pyramidal cells can be predicted more accurately by using the spike times of simultaneously recorded neurons in addition to the animals location in space. This improvement remained when the spatial prediction was refined with a spatially dependent theta phase modulation(5-8). The time window in which spike times are best predicted from simultaneous peer activity is 10-30 ms, suggesting that cell assemblies are synchronized at this timescale. Because this temporal window matches the membrane time constant of pyramidal neurons(9), the period of the hippocampal gamma oscillation(10) and the time window for synaptic plasticity(11), we propose that cooperative activity at this timescale is optimal for information transmission and storage in cortical circuits.},
author = {Harris, Kenneth D and Jozsef Csicsvari and Hirase, Hajima and Dragoi, George and Buzsáki, György},
journal = {Nature},
number = {6948},
pages = {552 -- 556},
publisher = {Nature Publishing Group},
title = {{Organization of cell assemblies in the hippocampus}},
doi = {0.1038/nature01834},
volume = {424},
year = {2003},
}
@article{3528,
abstract = {Gamma frequency oscillations (30-100 Hz) have been suggested to underlie various cognitive and motor functions. Here, we examine the generation of gamma oscillation currents in the hippocampus, using two-dimensional, 96-site silicon probes. Two gamma generators were identified, one in the dentate gyrus and another in the CA3-CA1 regions. The coupling strength between the two oscillators varied during both theta and nontheta states. Both pyramidal cells and interneurons were phase-locked to gamma waves. Anatomical connectivity, rather than physical distance, determined the coupling strength of the oscillating neurons. CA3 pyramidal neurons discharged CA3 and CA1 interneurons at latencies indicative of monosynaptic connections. Intrahippocampal gamma oscillation emerges in the CA3 recurrent system, which entrains the CA1 region via its interneurons.},
author = {Jozsef Csicsvari and Jamieson, Brian G and Wise, Kensall D and Buzsáki, György},
journal = {Neuron},
number = {2},
pages = {311 -- 322},
publisher = {Elsevier},
title = {{Mechanisms of gamma oscillations in the hippocampus of the behaving rat}},
doi = {10.1016/S0896-6273(02)01169-8},
volume = {37},
year = {2003},
}
@article{3529,
abstract = {Parallel recording of neuronal activity in the behaving animal is a prerequisite for our understanding of neuronal representation and storage of information. Here we describe the development of micro-machined silicon microelectrode arrays for unit and local field recordings. The two-dimensional probes with 96 or 64 recording sites provided high-density recording of unit and field activity with minimal tissue displacement or damage. The on-chip active circuit eliminated movement and other artifacts and greatly reduced the weight of the headgear. The precise geometry of the recording tips allowed for the estimation of the spatial location of the recorded neurons and for high-resolution estimation of extracellular current source density. Action potentials could be simultaneously recorded from the soma and dendrites of the same neurons. Silicon technology is a promising approach for high-density, high-resolution sampling of neuronal activity in both basic research and prosthetic devices.},
author = {Jozsef Csicsvari and Henze, Darrell A and Jamieson, Brian G and Harris, Kenneth D and Sirota, Anton M and Bartho, Peter and Wise, Kensall D and Buzsáki, György},
journal = {Journal of Neurophysiology},
number = {2},
pages = {1314 -- 1323},
publisher = {American Physiological Society},
title = {{Massively parallel recording of unit and local field potentials with silicon-based electrodes}},
doi = {10.1152/jn.00116.2003},
volume = {90},
year = {2003},
}
@article{3536,
abstract = {Genetic engineering of the mouse brain allows investigators to address novel hypotheses in vivo. Because of the paucity of information on the network patterns of the mouse hippocampus, we investigated the electrical patterns in the behaving animal using multisite silicon probes and wire tetrodes. Theta (6-9 Hz) and gamma (40-100 Hz) oscillations were present during exploration and rapid eye movement sleep. Gamma power and theta power were comodulated and gamma power varied as a function of the theta cycle. Pyramidal cells and putative interneurons were phase-locked to theta oscillations. During immobility, consummatory behaviors and slow-wave sleep, sharp waves were present in cornu ammonis region CA1 of the hippocampus stratum radiatum associated with 140-200-Hz “ripples” in the pyramidal cell layer and population burst of CA1 neurons. In the hilus, large-amplitude “dentate spikes” occurred in association with increased discharge of hilar neurons. The amplitude of field patterns was larger in the mouse than in the rat, likely reflecting the higher neuron density in a smaller brain. We suggest that the main hippocampal network patterns are mediated by similar pathways and mechanisms in mouse and rat. },
author = {Buzsáki, György and Buhl, Derek L and Harris, Kenneth D and Jozsef Csicsvari and Czéh, Boldizsár and Morozov, Alexei},
journal = {Neuroscience},
number = {1},
pages = {201 -- 211},
publisher = {Elsevier},
title = {{Hippocampal network patterns of activity in the mouse}},
doi = {10.1016/S0306-4522(02)00669-3},
volume = {116},
year = {2003},
}
@article{3543,
abstract = {Both neocortical and hippocampal networks organize the firing patterns of their neurons by prominent oscillations during sleep, but the functional role of these rhythms is not well understood. Here, we show a robust correlation of neuronal discharges between the somatosensory cortex and hippocampus on both slow and fine time scales in the mouse and rat. Neuronal bursts in deep cortical layers, associated with sleep spindles and delta waves/slow rhythm, effectively triggered hippocampal discharges related to fast (ripple) oscillations. We hypothesize that oscillation-mediated temporal links coordinate specific information transfer between neocortical and hippocampal cell assemblies. Such a neocortical-hippocampal interplay may be important for memory consolidation.},
author = {Sirota, Anton M and Jozsef Csicsvari and Buhl, Derek L and Buzsáki, György},
journal = {PNAS},
number = {4},
pages = {2065 -- 2069},
publisher = {National Academy of Sciences},
title = {{Communication between neocortex and hippocampus during sleep in rodents}},
doi = {10.1073/pnas.0437938100},
volume = {100},
year = {2003},
}
@inproceedings{3556,
abstract = {We define the Morse-Smale complex of a Morse function over a 3-manifold as the overlay of the descending and as- cending manifolds of all critical points. In the generic case, its 3-dimensional cells are shaped like crystals and are sepa- rated by quadrangular faces. In this paper, we give a combi- natorial algorithm for constructing such complexes for piece- wise linear data.},
author = {Herbert Edelsbrunner and Harer, John and Natarajan, Vijay and Pascucci, Valerio},
pages = {361 -- 370},
publisher = {ACM},
title = {{Morse-Smale complexes for piecewise linear 3-manifolds}},
doi = {10.1145/777792.777846},
year = {2003},
}
@inbook{3573,
abstract = {Given a finite point set in R, the surface reconstruction problem asks for a surface that passes through many but not necessarily all points. We describe an unambigu- ous definition of such a surface in geometric and topological terms, and sketch a fast algorithm for constructing it. Our solution overcomes past limitations to special point distributions and heuristic design decisions.},
author = {Herbert Edelsbrunner},
booktitle = {Discrete & Computational Geometry},
pages = {379 -- 404},
publisher = {Springer},
title = {{Surface reconstruction by wrapping finite sets in space}},
doi = {10.1007/978-3-642-55566-4_17},
year = {2003},
}
@article{3584,
abstract = {We develop fast algorithms for computing the linking number of a simplicial complex within a filtration.We give experimental results in applying our work toward the detection of non-trivial tangling in biomolecules, modeled as alpha complexes.},
author = {Edelsbrunner, Herbert and Zomorodian, Afra},
journal = {Homology, Homotopy and Applications},
number = {2},
pages = {19 -- 37},
publisher = {International Press},
title = {{Computing linking numbers of a filtration}},
volume = {5},
year = {2003},
}
@article{3593,
abstract = {Temporal logics such as Computation Tree Logic (CTL) and Linear Temporal Logic (LTL) have become popular for specifying temporal properties over a wide variety of planning and verification problems. In this paper we work towards building a generalized framework for automated reasoning based on temporal logics. We present a powerful extension of CTL with first-order quantification over the set of reachable states for reasoning about extremal properties of weighted labeled transition systems in general. The proposed logic, which we call Weighted Quantified Computation Tree Logic (WQCTL), captures the essential elements common to the domain of planning and verification problems and can thereby be used as an effective specification language in both domains. We show that in spite of the rich, expressive power of the logic, we are able to evaluate WQCTL formulas in time polynomial in the size of the state space times the length of the formula. Wepresent experimental results on the WQCTL verifier.},
author = {Krishnendu Chatterjee and Dasgupta, Pallab and Chakrabarti, Partha P},
journal = {Journal of Automated Reasoning},
number = {2},
pages = {205 -- 232},
publisher = {Springer},
title = {{A branching time temporal framework for quantitative reasoning}},
doi = {10.1023/A:1023217515688},
volume = {30},
year = {2003},
}
@article{3618,
abstract = {There are several analyses in evolutionary ecology which assume that a family of offspring has come from only two parents. Here, we present a simple test for detecting when a batch involves two or more subfamilies. It is based on the fact that the mixing of families generates associations amongst unlinked marker loci. We also present simulations illustrating the power of our method for varying numbers of loci, alleles per locus and genotyped individuals.},
author = {Vines, Timothy H and Nicholas Barton},
journal = {Molecular Ecology},
number = {7},
pages = {1999 -- 2002},
publisher = {Wiley-Blackwell},
title = {{A new approach to detecting mixed families}},
doi = {10.1046/j.1365-294X.2003.01867.x},
volume = {12},
year = {2003},
}
@article{3619,
abstract = {What is the chance that some part of a stretch of genome will survive? In a population of constant size, and with no selection, the probability of survival of some part of a stretch of map length y<1 approaches View the MathML source for View the MathML source. Thus, the whole genome is certain to be lost, but the rate of loss is extremely slow. This solution extends to give the whole distribution of surviving block sizes as a function of time. We show that the expected number of blocks at time t is 1+yt and give expressions for the moments of the number of blocks and the total amount of genome that survives for a given time. The solution is based on a branching process and assumes complete interference between crossovers, so that each descendant carries only a single block of ancestral material. We consider cases where most individuals carry multiple blocks, either because there are multiple crossovers in a long genetic map, or because enough time has passed that most individuals in the population are related to each other. For species such as ours, which have a long genetic map, the genome of any individual which leaves descendants (∼80% of the population for a Poisson offspring number with mean two) is likely to persist for an extremely long time, in the form of a few short blocks of genome.},
author = {Baird, Stuart J and Nicholas Barton and Etheridge, Alison M},
journal = {Theoretical Population Biology},
number = {4},
pages = {451 -- 471},
publisher = {Academic Press},
title = {{The distribution of surviving blocks of an ancestral genome}},
doi = {10.1016/S0040-5809(03)00098-4},
volume = {64},
year = {2003},
}
@article{3620,
abstract = {Stable hybrid zones in which ecologically divergent taxa give rise to a range of recombinants are natural laboratories in which the genetic basis of adaptation and reproductive isolation can be unraveled. One such hybrid zone is formed by the fire-bellied toads Bombina bombina and B. variegata (Anura: Discoglossidae). Adaptations to permanent and ephemeral breeding habitats, respectively, have shaped numerous phenotypic differences between the taxa. All of these are, in principle, candidates for a genetic dissection via QTL mapping. We present here a linkage map of 28 codominant and 10 dominant markers in the Bombina genome. In an F2 cross, markers that were mainly microsatellites, SSCPs or allozymes were mapped to 20 linkage groups. Among the 40 isolated CA microsatellites, we noted a preponderance of compound and frequently interleaved CA-TA repeats as well as a striking polarity at the 5′ end of the repeats.},
author = {Nürnberger, Beate and Hofman, Sebastian and Förg-Brey, Bqruni and Praetzel, Gabriele and Maclean, Alan W and Szymura, Jacek M and Abbott, Catherine M and Nicholas Barton},
journal = {Heredity},
number = {2},
pages = {136 -- 142},
publisher = {Nature Publishing Group},
title = {{A linkage map for the hybridising toads Bombina bombina and B. variegata (Anura: Discoglossidae)}},
doi = {10.1038/sj.hdy.6800291},
volume = {91},
year = {2003},
}
@phdthesis{3678,
author = {Christoph Lampert},
booktitle = {Bonner Mathematische Schriften},
pages = {1 -- 165},
publisher = {Universität Bonn, Fachbibliothek Mathematik},
title = {{The Neumann operator in strictly pseudoconvex domains with weighted Bergman metric }},
volume = {356},
year = {2003},
}
@article{3725,
abstract = {The combination of high-resolution atomic force microscopy (AFM) imaging and single-molecule force-spectroscopy was employed to unfold single bacteriorhodopsins (BR) from native purple membrane patches at various physiologically relevant temperatures. The unfolding spectra reveal detailed insight into the stability of individual structural elements of BR against mechanical unfolding. Intermittent states in the unfolding process are associated with the stepwise unfolding of alpha-helices, whereas other states are associated with the unfolding of polypeptide loops connecting the alpha-helices. It was found that the unfolding forces of the secondary structures considerably decreased upon increasing the temperature from 8 to 52°C. Associated with this effect, the probability of individual unfolding pathways of BR was significantly influenced by the temperature. At lower temperatures, transmembrane alpha-helices and extracellular polypeptide loops exhibited sufficient stability to individually establish potential barriers against unfolding, whereas they predominantly unfolded collectively at elevated temperatures. This suggests that increasing the temperature decreases the mechanical stability of secondary structural elements and changes molecular interactions between secondary structures, thereby forcing them to act as grouped structures.},
author = {Harald Janovjak and Kessler, Max and Oesterhelt, Dieter and Gaub, Hermann and Mueller, Daniel J},
journal = {EMBO Journal},
number = {19},
pages = {5220 -- 5229},
publisher = {Wiley-Blackwell},
title = {{Unfolding pathways of native bacteriorhodopsin depend on temperature}},
doi = {10.1093/emboj/cdg509},
volume = {22},
year = {2003},
}
@article{3752,
abstract = {We use the lac operon in Escherichia coli as a prototype system to illustrate the current state, applicability, and limitations of modeling the dynamics of cellular networks. We integrate three different levels of description (molecular, cellular, and that of cell population) into a single model, which seems to capture many experimental aspects of the system.},
author = {Vilar,Jose M and Calin Guet and Leibler, Stanislas},
journal = {Journal of Cell Biology},
number = {3},
pages = {471 -- 476},
publisher = {Rockefeller University Press},
title = {{Modeling network dynamics: the lac operon, a case study}},
doi = {10.1083/jcb.200301125},
volume = {161},
year = {2003},
}
@article{3804,
abstract = {Kv3 channels are thought to be essential for the fast-spiking (FS) phenotype in GABAergic interneurons, but how these channels confer the ability to generate action potentials (APs) at high frequency is unknown. To address this question, we developed a fast dynamic-clamp system (approximately 50 kHz) that allowed us to add a Kv3 model conductance to CA1 oriens alveus (OA) interneurons in hippocampal slices. Selective pharmacological block of Kv3 channels by 0.3 mm 4-aminopyridine or 1 mm tetraethylammonium ions led to a marked broadening of APs during trains of short stimuli and a reduction in AP frequency during 1 sec stimuli. The addition of artificial Kv3 conductance restored the original AP pattern. Subtraction of Kv3 conductance by dynamic clamp mimicked the effects of the blockers. Application of artificial Kv3 conductance also led to FS in OA interneurons after complete K+ channel block and even induced FS in hippocampal pyramidal neurons in the absence of blockers. Adding artificial Kv3 conductance with altered deactivation kinetics revealed a nonmonotonic relationship between mean AP frequency and deactivation rate, with a maximum slightly above the original value. Insertion of artificial Kv3 conductance with either lowered activation threshold or inactivation also led to a reduction in the mean AP frequency. However, the mechanisms were distinct. Shifting the activation threshold induced adaptation, whereas adding inactivation caused frequency-dependent AP broadening. In conclusion, Kv3 channels are necessary for the FS phenotype of OA interneurons, and several of their gating properties appear to be optimized for high-frequency repetitive activity.},
author = {Lien, Cheng-Chang and Peter Jonas},
journal = {Journal of Neuroscience},
number = {6},
pages = {2058 -- 68},
publisher = {Society for Neuroscience},
title = {{Kv3 potassium conductance is necessary and kinetically optimized for high-frequency action potential generation in hippocampal interneurons}},
volume = {23},
year = {2003},
}
@article{3806,
abstract = {To probe exocytosis at a cortical glutamatergic synapse, we made capacitance measurements in whole-cell recorded hippocampal mossy fiber terminals. Evaluation of different methods by using a morphology-based equivalent electrical model revealed that quantitative capacitance measurements are possible in this presynaptic structure. Voltage pulses leading to presynaptic Ca2+ inflow evoked large capacitance signals that showed saturation with increasing pulse duration. The mean peak capacitance increase was 100 fF, corresponding to a pool of approximately 1,400 releasable vesicles. Thus hippocampal mossy fiber synapses have a vesicular "maxipool." Large pool size and rapid vesicle recycling may underlie the uniquely large extent of activity-dependent plasticity in this synapse.},
author = {Hallermann, Stefan and Pawlu, Christian and Peter Jonas and Heckmann, Manfred},
journal = {PNAS},
number = {15},
pages = {8975 -- 80},
publisher = {National Academy of Sciences},
title = {{A large pool of releasable vesicles in a cortical glutamatergic synapse}},
doi = {10.1073/pnas.1432836100},
volume = {100},
year = {2003},
}
@inproceedings{3897,
abstract = {Many verification, planning, and control problems can be modeled as games played on state-transition graphs by one or two players whose conflicting goals are to form a path in the graph. The focus here is on simple stochastic parity games, that is, two-player games with turn-based probabilistic transitions and omega-regular objectives formalized as parity (Rabin chain) winning conditions. An efficient translation from simple stochastic parity games to nonstochastic parity games is given. As many algorithms are known for solving the latter, the translation yields efficient algorithms for computing the states of a simple stochastic parity game from which a player can win with probability 1. An important special case of simple stochastic parity games are the Markov decision processes with Buchi objectives. For this special case a first provably subquadratic algorithm is given for computing the states from which the single player has a strategy to achieve a Buchi objective with probability 1. For game graphs with m edges the algorithm works in time O(mrootm). Interestingly, a similar technique sheds light on the question of the computational complexity of solving simple Buchi games and yields the first provably subquadratic algorithm, with a running time of O(n(2)/log n) for game graphs with n vertices and O(n) edges.},
author = {Krishnendu Chatterjee and Jurdziński, Marcin and Thomas Henzinger},
pages = {100 -- 113},
publisher = {Springer},
title = {{Simple stochastic parity games}},
doi = {10.1007/978-3-540-45220-1_11},
volume = {2803},
year = {2003},
}
@inproceedings{3898,
abstract = {We study the problem of determining stack boundedness and the exact maximum stack size for three classes of interrupt-driven programs. Interrupt-driven programs axe used in many real-time applications that require responsive interrupt handling. In order to ensure responsiveness, programmers often enable interrupt processing in the body of lower-priority interrupt handlers. In such programs a programming error can allow interrupt handlers to be interrupted in cyclic fashion to lead to an unbounded stack, causing the system to crash. For a restricted class of interrupt-driven programs, we show that there is a polynomial-time procedure to check stack boundedness, while determining the exact maximum stack size is PSPACE-complete. For a larger class of programs, the two problems are both PSPACE-complete, and for the largest class of programs we consider, the two problems are PSPACE-hard and can be solved in exponential time.},
author = {Krishnendu Chatterjee and Ma, Di and Majumdar, Ritankar S and Zhao, Tian and Thomas Henzinger and Palsberg, Jens},
pages = {109 -- 126},
publisher = {Springer},
title = {{Stack size analysis for interrupt-driven programs}},
doi = {10.1007/3-540-44898-5_7},
volume = {2694},
year = {2003},
}
@inproceedings{3425,
author = {Bollenbach, Mark Tobias and Strother, T. and Bauer, Wolfgang},
pages = {277 -- 288},
publisher = {Springer},
title = {{3D supernova collapse calculations}},
doi = {10.1007/978-1-4020-2705-5_21},
volume = {166},
year = {2003},
}
@article{3797,
author = {Bauer, Wolfgang and Kleine Berkenbusch, Marco and Bollenbach, Mark Tobias},
journal = {Revista Mexicana De Fisica},
number = {4},
pages = {1 -- 6},
publisher = {Sociedad Mexicana de Física},
title = {{Breaking atomic nuclei into little pieces: evidence for a phase transition}},
volume = {49},
year = {2003},
}
@article{4146,
abstract = {During vertebrate gastrulation, highly coordinated cellular rearrangements lead to the formation of the three germ layers, ectoderm, mesoderm and endoderm. In zebrafish, silberblick (slb)/wnt11 regulates normal gastrulation movements by activating a signalling pathway similar to the Frizzled-signalling pathway, which establishes epithelial planar cell polarity (PCP) in Drosophila. However, the cellular mechanisms by which slb/wnt11 functions during zebrafish gastrulation are still unclear. Using high-resolution two-photon confocal imaging followed by computer-assisted reconstruction and motion analysis, we have analysed the movement and morphology of individual cells in three dimensions during the course of gastrulation. We show that in slb-mutant embryos, hypoblast cells within the forming germ ring have slower, less directed migratory movements at the onset of gastrulation. These aberrant cell movements are accompanied by defects in the orientation of cellular processes along the individual movement directions of these cells. We conclude that slb/wnt11-mediated orientation of cellular processes plays a role in facilitating and stabilising movements of hypoblast cells in the germ ring, thereby pointing at a novel function of the slb/wnt11 signalling pathway for the regulation of migratory cell movements at early stages of gastrulation.},
author = {Ulrich, Florian and Concha, Miguel and Heid, Paul and Voss, Ed and Witzel, Sabine and Roehl, Henry and Tada, Masazumi and Wilson, Stephen and Adams, Richard and Soll, David and Heisenberg, Carl-Philipp J},
journal = {Development},
number = {22},
pages = {5375 -- 5384},
publisher = {Company of Biologists},
title = {{Slb/Wnt11 controls hypoblast cell migration and morphogenesis at the onset of zebrafish gastrulation}},
doi = {10.1242/dev.00758},
volume = {130},
year = {2003},
}
@article{4169,
abstract = {Background: During vertebrate gastrulation, cell polarization and migration are core components in the cellular rearrangements that lead to the formation of the three germ layers, ectoderm, mesoderm, and endoderm. Previous studies have implicated the Wnt/planar cell polarity (PCP) signaling pathway in controlling cell morphology and movement during gastrulation. However, cell polarization and directed cell migration are reduced but not completely abolished in the absence of Wnt/PCP signals; this observation indicates that other signaling pathways must be involved. Results: We show that Phosphoinositide 3-Kinases (PI3Ks) are required at the onset of zebrafish gastrulation in mesendodermal cells for process formation and cell polarization. Platelet Derived Growth Factor (PDGF) functions upstream of PI3K, while Protein Kinase B (PKB), a downstream effector of PI3K activity, localizes to the leading edge of migrating mesendodermal cells. In the absence of PI3K activity, PKB localization and cell polarization are strongly reduced in mesendodermal cells and are followed by slower but still highly coordinated and directed movements of these cells. Conclusions: We have identified a novel role of a signaling pathway comprised of PDGF, PI3K, and PKB in the control of morphogenetic cell movements during gastrulation. Furthermore, our findings provide insight into the relationship between cell polarization and directed cell migration at the onset of zebrafish gastrulation.},
author = {Montero, Juan and Kilian, Beate and Chan, Joanne and Bayliss, Peter and Heisenberg, Carl-Philipp J},
journal = {Current Biology},
number = {15},
pages = {1279 -- 1289},
publisher = {Cell Press},
title = {{Phosphoinositide 3-kinase is required for process outgrowth and cell polarization of gastrulating mesendodermal cells}},
doi = {10.1016/S0960-9822(03)00505-0},
volume = {13},
year = {2003},
}
@article{4168,
abstract = {Recent studies show that signaling through integrin receptors is required for normal cell movements during Xenopus gastrulation. Integrins function in this process by modulating the activity of cadherin adhesion molecules within tissues undergoing convergence and extension movements.},
author = {Montero, Juan and Heisenberg, Carl-Philipp J},
journal = {Developmental Cell},
number = {2},
pages = {190 -- 191},
publisher = {Cell Press},
title = {{Adhesive crosstalk in gastrulation}},
doi = {10.1016/S1534-5807(03)00235-1},
volume = {5},
year = {2003},
}
@article{4185,
abstract = {Wnt genes play important roles in regulating patterning and morphogenesis during vertebrate gastrulation. In zebrafish, slb/wnt11 is required for convergence and extension movements, but not cell fate specification during gastrulation. To determine if other Wnt genes functionally interact with slb/wnt11, we analysed the role of ppt/wnt5 during zebrafish gastrulation. ppt/wnt5 is maternally provided and zygotically expressed at all stages during gastrulation. The analysis of ppt mutant embryos reveals that Ppt/Wnt5 regulates cell elongation and convergent extension movements in posterior regions of the gastrula, while its function in more anterior regions is largely redundant to that of Slb/Wnt11. Frizzled-2 functions downstream of ppt/wnt5, indicating that it might act as a receptor for Ppt/Wnt5 in this process. The characterisation of the role of Ppt/Wnt5 provides insight into the functional diversity of Wnt genes in regulating vertebrate gastrulation movements. (C) 2003 Elsevier Science Ireland Ltd. All rights reserved.},
author = {Kilian, Beate and Mansukoski, Hannu and Barbosa, Filipa and Ulrich, Florian and Tada, Masazumi and Heisenberg, Carl-Philipp J},
journal = {Mechanisms of Development},
number = {4},
pages = {467 -- 476},
publisher = {Elsevier},
title = {{The role of Ppt/Wnt5 in regulating cell shape and movement during zebrafish gastrulation}},
doi = {10.1016/S0925-4773(03)00004-2},
volume = {120},
year = {2003},
}
@article{4240,
author = {González, J. and de Vladar, Harold and Rebolledo, Morella},
journal = {Acta Científica Venezolana},
pages = {263 -- 273},
publisher = {Asociación Venezolana para el Avance de la Ciencia.},
title = {{New Late–Intensification Schedules for Cancer Treatments}},
doi = {3800},
volume = {54},
year = {2003},
}
@phdthesis{4416,
abstract = {Methods for the formal specification and verification of systems are indispensible for the development of complex yet correct systems. In formal verification, the designer describes the system in a modeling language with a well-defined semantics, and this system description is analyzed against a set of correctness requirements. Model checking is an algorithmic technique to check that a system description indeed satisfies correctness requirements given as logical specifications. While successful in hardware verification, the potential for model checking for software and embedded systems has not yet been realized. This is because traditional model checking focuses on systems modeled as finite state-transition graphs. While a natural model for hardware (especially synchronous hardware), state-transition graphs often do not capture software and embedded systems at an appropriate level of granularity. This dissertation considers two orthogonal extensions to finite state-transition graphs making model checking techniques applicable to both a wider class of systems and a wider class of properties.
The first direction is an extension to infinite-state structures finitely represented using constraints and operations on constraints. Infinite state arises when we wish to model variables with unbounded range (e.g., integers), or data structures, or real time. We provide a uniform framework of symbolic region algebras to study model checking of infinite-state systems. We also provide sufficient language-independent termination conditions for symbolic model checking algorithms on infinite state systems.
The second direction supplements verification with game theoretic reasoning. Games are natural models for interactions between components. We study game theoretic behavior with winning conditions given by temporal logic objectives both in the deterministic and in the probabilistic context. For deterministic games, we provide an extremal model characterization of fixpoint algorithms that link solutions of verification problems to solutions for games. For probabilistic games we study fixpoint characterization of winning probabilities for games with omega-regular winning objectives, and construct (epsilon-)optimal winning strategies.},
author = {Majumdar, Ritankar},
pages = {1 -- 201},
publisher = {University of California, Berkeley},
title = {{Symbolic algorithms for verification and control}},
year = {2003},
}
@phdthesis{4425,
abstract = {Giotto provides a time-triggered programmer’s model for the implementation of embedded control systems with hard real-time constraints. Giotto’s precise semantics and predictabil- ity make it suitable for safety-critical applications.
Giotto is based around the idea that time-triggered task invocation together with time-triggered mode switching can form a useful programming model for real-time systems. To substantiate this claim, we describe the use of Giotto to refactor the software of a small, autonomous helicopter. The ease with which Giotto expresses the existing software provides evidence that Giotto is an appropriate programming language for control systems.
Since Giotto is a real-time programming language, ensuring that Giotto programs meet their deadlines is crucial. To study precedence-constrained Giotto scheduling, we first examine single-mode, single-processor scheduling. We extend to an infinite, periodic setting the classical problem of meeting deadlines for a set of tasks with release times, deadlines, precedence constraints, and preemption. We then develop an algorithm for scheduling Giotto programs on a single processor by representing Giotto programs as instances of the extended scheduling problem.
Next, we study multi-mode, single-processor Giotto scheduling. This problem is different from classical scheduling problems, since in our precedence-constrained approach, the deadlines of tasks may vary depending on the mode switching behavior of the program. We present conditional scheduling models which capture this varying-deadline behavior. We develop polynomial-time algorithms for some conditional scheduling models, and prove oth- ers to be computationally hard. We show how to represent multi-mode Giotto programs as instances of the model, resulting in an algorithm for scheduling multi-mode Giotto programs on a single processor.
Finally, we show that the problem of scheduling Giotto programs for multiple net- worked processors is strongly NP-hard.},
author = {Horowitz, Benjamin},
pages = {1 -- 237},
publisher = {University of California, Berkeley},
title = {{Giotto: A time-triggered language for embedded programming}},
year = {2003},
}
@article{8519,
author = {Kaloshin, Vadim},
issn = {0020-9910},
journal = {Inventiones mathematicae},
keywords = {General Mathematics},
number = {3},
pages = {451--512},
publisher = {Springer Nature},
title = {{The existential Hilbert 16-th problem and an estimate for cyclicity of elementary polycycles}},
doi = {10.1007/s00222-002-0244-9},
volume = {151},
year = {2003},
}
@article{204,
abstract = {Let k⩾5 be an integer, and let x⩾1 be an arbitrary real number. We derive a bound[Formula presented] for the number of positive integers less than or equal to x which can be represented as a sum of two non-negative coprime kth powers, in essentially more than one way.},
author = {Timothy Browning},
journal = {Journal of Number Theory},
number = {2},
pages = {293 -- 318},
publisher = {Academic Press},
title = {{Equal Sums of Two kth Powers}},
doi = {10.1006/jnth.2002.2800},
volume = {96},
year = {2002},
}
@inbook{2338,
author = {Lieb, Élliott H and Solovej, Jan P and Robert Seiringer and Yngvason, Jakob},
booktitle = {Current Developments in Mathematics, 2001},
pages = {131 -- 178},
publisher = {International Press},
title = {{The ground state of the Bose gas}},
doi = {http://arxiv.org/abs/math-ph/0204027},
year = {2002},
}
@inproceedings{2339,
author = {Robert Seiringer},
editor = {Weder, Richardo and Exner, Pavel and Grébert, Benoit},
pages = {281 -- 286},
publisher = {World Scientific Publishing},
title = {{Symmetry breaking in a model of a rotating Bose gas}},
doi = {10.1090/conm/307},
volume = {307},
year = {2002},
}
@article{2349,
abstract = {The Bose-Einstein condensation (BEC) of the ground state of bosonic atoms in a trap was discussed. The BEC was proved for bosons with two-body repulsive interaction potentials in the dilute limit, starting from the basic Schrodinger equation. The BEC was 100% into the state which minimized the Gross-Pitaevskii energy functional. The analysis also included rigorous proof of BEC in a physically realistic, continuum model.},
author = {Lieb, Élliott H and Robert Seiringer},
journal = {Physical Review Letters},
number = {17},
pages = {1704091 -- 1704094},
publisher = {American Physical Society},
title = {{Proof of Bose-Einstein condensation for dilute trapped gases}},
doi = {10.1103/PhysRevLett.88.170409},
volume = {88},
year = {2002},
}
@article{2350,
abstract = {Using the Pauli-Fierz model of non-relativistic quantum electrodynamics, we calculate the binding energy of an electron in the field of a nucleus of charge Z and in presence of the quantized radiation field. We consider the case of small coupling constant α, but fixed Zα and ultraviolet cut-off Λ. We prove that after renormalizing the mass the binding energy has, to leading order in α, a finite limit as Λ goes to infinity; i.e., the cut-off can be removed. The expression for the ground state energy shift thus obtained agrees with Bethe's formula for small values of Zα, but shows a different behavior for bigger values.},
author = {Hainzl, Christian and Robert Seiringer},
journal = {Advances in Theoretical and Mathematical Physics},
number = {5},
pages = {847 -- 871},
publisher = {International Press},
title = {{Mass renormalization and energy level shift in non-relativistic QED}},
volume = {6},
year = {2002},
}
@article{2351,
abstract = {We study the Gross-Pitaevskii functional for a rotating two-dimensional Bose gas in a trap. We prove that there is a breaking of the rotational symmetry in the ground state; more precisely, for any value of the angular velocity and for large enough values of the interaction strength, the ground state of the functional is not an eigenfunction of the angular momentum. This has interesting consequences on the Bose gas with spin; in particular, the ground state energy depends non-trivially on the number of spin components, and the different components do not have the same wave function. For the special case of a harmonic trap potential, we give explicit upper and lower bounds on the critical coupling constant for symmetry breaking.},
author = {Robert Seiringer},
journal = {Communications in Mathematical Physics},
number = {3},
pages = {491 -- 509},
publisher = {Springer},
title = {{Gross-Pitaevskii theory of the rotating Bose gas}},
doi = {10.1007/s00220-002-0695-2},
volume = {229},
year = {2002},
}
@article{2352,
abstract = {We present a generalization of the Fefferman-de la Llave decomposition of the Coulomb potential to quite arbitrary radial functions V on ℝn going to zero at infinity. This generalized decomposition can be used to extend previous results on N-body quantum systems with Coulomb interaction to a more general class of interactions. As an example of such an application, we derive the high density asymptotics of the ground state energy of jellium with Yukawa interaction in the thermodynamic limit, using a correlation estimate by Graf and Solovej.},
author = {Hainzl, Christian and Robert Seiringer},
journal = {Letters in Mathematical Physics},
number = {1},
pages = {75 -- 84},
publisher = {Springer},
title = {{General decomposition of radial functions on ℝn and applications to N-body quantum systems}},
doi = {10.1023/A:1020204818938},
volume = {61},
year = {2002},
}
@article{2353,
abstract = {A commonly used theoretical definition of superfluidity in the ground state of a Bose gas is based on the response of the system to an imposed velocity field or, equivalently, to twisted boundary conditions in a box. We are able to carry out this program in the case of a dilute interacting Bose gas in a trap, and we prove that a gas with repulsive interactions is 100% superfluid in the dilute limit in which the Gross-Pitaevskii equation is exact. This is the first example in an experimentally realistic continuum model in which superfluidity is rigorously verified.},
author = {Lieb, Élliott H and Robert Seiringer and Yngvason, Jakob},
journal = {Physical Review B - Condensed Matter and Materials Physics},
number = {13},
publisher = {American Physical Society},
title = {{Superfluidity in dilute trapped Bose gases}},
doi = {10.1103/PhysRevB.66.134529},
volume = {66},
year = {2002},
}
@article{2420,
abstract = {A corner cut in dimension d is a finite subset of N0d that can be separated from its complement in N0d by an affine hyperplane disjoint from N0d. Corner cuts were first investigated by Onn and Sturmfels [Adv. Appl. Math. 23 (1999) 29-48], their original motivation stemmed from computational commutative algebra. Let us write (Nd0k)cut for the set of corner cuts of cardinality k; in the computational geometer's terminology, these are the k-sets of N0d. Among other things, Onn and Sturmfels give an upper bound of O(k2d(d-1)/(d+1)) for the size of (Nd0k)cut when the dimension is fixed. In two dimensions, it is known (see [Corteel et al., Adv. Appl. Math. 23 (1) (1999) 49-53]) that #(Nd0k)cut = Θ(k log k). We will see that in general, for any fixed dimension d, the order of magnitude of #(Nd0k)cut is between kd-1 log k and (k log k)d-1. (It has been communicated to me that the same bounds have been found independently by G. Rémond.) In fact, the elements of (Nd0k)cut correspond to the vertices of a certain polytope, and what our proof shows is that the above upper bound holds for the total number of flags of that polytope.},
author = {Uli Wagner},
journal = {Advances in Applied Mathematics},
number = {2},
pages = {152 -- 161},
publisher = {ACM},
title = {{On the number of corner cuts}},
doi = {10.1016/S0196-8858(02)00014-3},
volume = {29},
year = {2002},
}
@inproceedings{2421,
abstract = {Intersection graphs of disks and of line segments, respectively, have been well studied, because of both, practical applications and theoretically interesting properties of these graphs. Despite partial results, the complexity status of the Clique problem for these two graph classes is still open. Here, we consider the Clique problem for intersection graphs of ellipses which in a sense, interpolate between disc and ellipses, and show that it is APX-hard in that case. Moreover, this holds even if for all ellipses, the ratio of the larger over the smaller radius is some prescribed number. To our knowledge, this is the first hardness result for the Clique problem in intersection graphs of objects with finite description complexity. We also describe a simple approximation algorithm for the case of ellipses for which the ratio of radii is bounded.},
author = {Ambühl, Christoph and Uli Wagner},
pages = {489 -- 500},
publisher = {Springer},
title = {{On the Clique problem in intersection graphs of ellipses}},
doi = {10.1007/3-540-36136-7_43},
volume = {2518},
year = {2002},
}