---
_id: '313'
abstract:
- lang: eng
text: 'Tunneling of a particle through a potential barrier remains one of the most
remarkable quantum phenomena. Owing to advances in laser technology, electric
fields comparable to those electrons experience in atoms are readily generated
and open opportunities to dynamically investigate the process of electron tunneling
through the potential barrier formed by the superposition of both laser and atomic
fields. Attosecond-time and angstrom-space resolution of the strong laser-field
technique allow to address fundamental questions related to tunneling, which are
still open and debated: Which time is spent under the barrier and what momentum
is picked up by the particle in the meantime? In this combined experimental and
theoretical study we demonstrate that for strong-field ionization the leading
quantum mechanical Wigner treatment for the time resolved description of tunneling
is valid. We achieve a high sensitivity on the tunneling barrier and unambiguously
isolate its effects by performing a differential study of two systems with almost
identical tunneling geometry. Moreover, working with a low frequency laser, we
essentially limit the non-adiabaticity of the process as a major source of uncertainty.
The agreement between experiment and theory implies two substantial corrections
with respect to the widely employed quasiclassical treatment: In addition to a
non-vanishing longitudinal momentum along the laser field-direction we provide
clear evidence for a non-zero tunneling time delay. This addresses also the fundamental
question how the transition occurs from the tunnel barrier to free space classical
evolution of the ejected electron.'
alternative_title:
- 'Journal of Physics: Conference Series'
article_number: '012004'
author:
- first_name: Nicolas
full_name: Camus, Nicolas
last_name: Camus
- first_name: Enderalp
full_name: Yakaboylu, Enderalp
id: 38CB71F6-F248-11E8-B48F-1D18A9856A87
last_name: Yakaboylu
orcid: 0000-0001-5973-0874
- first_name: Lutz
full_name: Fechner, Lutz
last_name: Fechner
- first_name: Michael
full_name: Klaiber, Michael
last_name: Klaiber
- first_name: Martin
full_name: Laux, Martin
last_name: Laux
- first_name: Yonghao
full_name: Mi, Yonghao
last_name: Mi
- first_name: Karen
full_name: Hatsagortsyan, Karen
last_name: Hatsagortsyan
- first_name: Thomas
full_name: Pfeifer, Thomas
last_name: Pfeifer
- first_name: Cristoph
full_name: Keitel, Cristoph
last_name: Keitel
- first_name: Robert
full_name: Moshammer, Robert
last_name: Moshammer
citation:
ama: 'Camus N, Yakaboylu E, Fechner L, et al. Experimental evidence for Wigner’s
tunneling time. In: Vol 999. American Physical Society; 2017. doi:10.1088/1742-6596/999/1/012004'
apa: 'Camus, N., Yakaboylu, E., Fechner, L., Klaiber, M., Laux, M., Mi, Y., … Moshammer,
R. (2017). Experimental evidence for Wigner’s tunneling time (Vol. 999). Presented
at the Annual International Laser Physics Workshop LPHYS, Kazan, Russian Federation:
American Physical Society. https://doi.org/10.1088/1742-6596/999/1/012004'
chicago: Camus, Nicolas, Enderalp Yakaboylu, Lutz Fechner, Michael Klaiber, Martin
Laux, Yonghao Mi, Karen Hatsagortsyan, Thomas Pfeifer, Cristoph Keitel, and Robert
Moshammer. “Experimental Evidence for Wigner’s Tunneling Time,” Vol. 999. American
Physical Society, 2017. https://doi.org/10.1088/1742-6596/999/1/012004.
ieee: N. Camus et al., “Experimental evidence for Wigner’s tunneling time,”
presented at the Annual International Laser Physics Workshop LPHYS, Kazan, Russian
Federation, 2017, vol. 999, no. 1.
ista: 'Camus N, Yakaboylu E, Fechner L, Klaiber M, Laux M, Mi Y, Hatsagortsyan K,
Pfeifer T, Keitel C, Moshammer R. 2017. Experimental evidence for Wigner’s tunneling
time. Annual International Laser Physics Workshop LPHYS, Journal of Physics: Conference
Series, vol. 999, 012004.'
mla: Camus, Nicolas, et al. Experimental Evidence for Wigner’s Tunneling Time.
Vol. 999, no. 1, 012004, American Physical Society, 2017, doi:10.1088/1742-6596/999/1/012004.
short: N. Camus, E. Yakaboylu, L. Fechner, M. Klaiber, M. Laux, Y. Mi, K. Hatsagortsyan,
T. Pfeifer, C. Keitel, R. Moshammer, in:, American Physical Society, 2017.
conference:
end_date: 2017-08-21
location: Kazan, Russian Federation
name: Annual International Laser Physics Workshop LPHYS
start_date: 2017-08-17
date_created: 2018-12-11T11:45:46Z
date_published: 2017-07-14T00:00:00Z
date_updated: 2023-02-23T12:36:07Z
day: '14'
ddc:
- '530'
department:
- _id: MiLe
doi: 10.1088/1742-6596/999/1/012004
external_id:
arxiv:
- '1611.03701'
file:
- access_level: open_access
checksum: 6e70b525a84f6d5fb175c48e9f5cb59a
content_type: application/pdf
creator: dernst
date_created: 2019-01-22T08:34:10Z
date_updated: 2020-07-14T12:46:00Z
file_id: '5871'
file_name: 2017_Physics_Camus.pdf
file_size: 949321
relation: main_file
file_date_updated: 2020-07-14T12:46:00Z
has_accepted_license: '1'
intvolume: ' 999'
issue: '1'
language:
- iso: eng
month: '07'
oa: 1
oa_version: Published Version
publication_identifier:
issn:
- '17426588'
publication_status: published
publisher: American Physical Society
publist_id: '7552'
quality_controlled: '1'
related_material:
record:
- id: '6013'
relation: later_version
status: public
scopus_import: 1
status: public
title: Experimental evidence for Wigner's tunneling time
tmp:
image: /images/cc_by.png
legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
short: CC BY (4.0)
type: conference
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 999
year: '2017'
...
---
_id: '601'
abstract:
- lang: eng
text: 'The conserved polymerase-Associated factor 1 complex (Paf1C) plays multiple
roles in chromatin transcription and genomic regulation. Paf1C comprises the five
subunits Paf1, Leo1, Ctr9, Cdc73 and Rtf1, and binds to the RNA polymerase II
(Pol II) transcription elongation complex (EC). Here we report the reconstitution
of Paf1C from Saccharomyces cerevisiae, and a structural analysis of Paf1C bound
to a Pol II EC containing the elongation factor TFIIS. Cryo-electron microscopy
and crosslinking data reveal that Paf1C is highly mobile and extends over the
outer Pol II surface from the Rpb2 to the Rpb3 subunit. The Paf1-Leo1 heterodimer
and Cdc73 form opposite ends of Paf1C, whereas Ctr9 bridges between them. Consistent
with the structural observations, the initiation factor TFIIF impairs Paf1C binding
to Pol II, whereas the elongation factor TFIIS enhances it. We further show that
Paf1C is globally required for normal mRNA transcription in yeast. These results
provide a three-dimensional framework for further analysis of Paf1C function in
transcription through chromatin. '
article_number: '15741'
article_processing_charge: No
author:
- first_name: Youwei
full_name: Xu, Youwei
last_name: Xu
- first_name: Carrie A
full_name: Bernecky, Carrie A
id: 2CB9DFE2-F248-11E8-B48F-1D18A9856A87
last_name: Bernecky
orcid: 0000-0003-0893-7036
- first_name: Chung
full_name: Lee, Chung
last_name: Lee
- first_name: Kerstin
full_name: Maier, Kerstin
last_name: Maier
- first_name: Björn
full_name: Schwalb, Björn
last_name: Schwalb
- first_name: Dimitri
full_name: Tegunov, Dimitri
last_name: Tegunov
- first_name: Jürgen
full_name: Plitzko, Jürgen
last_name: Plitzko
- first_name: Henning
full_name: Urlaub, Henning
last_name: Urlaub
- first_name: Patrick
full_name: Cramer, Patrick
last_name: Cramer
citation:
ama: Xu Y, Bernecky C, Lee C, et al. Architecture of the RNA polymerase II-Paf1C-TFIIS
transcription elongation complex. Nature Communications. 2017;8. doi:10.1038/ncomms15741
apa: Xu, Y., Bernecky, C., Lee, C., Maier, K., Schwalb, B., Tegunov, D., … Cramer,
P. (2017). Architecture of the RNA polymerase II-Paf1C-TFIIS transcription elongation
complex. Nature Communications. Nature Publishing Group. https://doi.org/10.1038/ncomms15741
chicago: Xu, Youwei, Carrie Bernecky, Chung Lee, Kerstin Maier, Björn Schwalb, Dimitri
Tegunov, Jürgen Plitzko, Henning Urlaub, and Patrick Cramer. “Architecture of
the RNA Polymerase II-Paf1C-TFIIS Transcription Elongation Complex.” Nature
Communications. Nature Publishing Group, 2017. https://doi.org/10.1038/ncomms15741.
ieee: Y. Xu et al., “Architecture of the RNA polymerase II-Paf1C-TFIIS transcription
elongation complex,” Nature Communications, vol. 8. Nature Publishing Group,
2017.
ista: Xu Y, Bernecky C, Lee C, Maier K, Schwalb B, Tegunov D, Plitzko J, Urlaub
H, Cramer P. 2017. Architecture of the RNA polymerase II-Paf1C-TFIIS transcription
elongation complex. Nature Communications. 8, 15741.
mla: Xu, Youwei, et al. “Architecture of the RNA Polymerase II-Paf1C-TFIIS Transcription
Elongation Complex.” Nature Communications, vol. 8, 15741, Nature Publishing
Group, 2017, doi:10.1038/ncomms15741.
short: Y. Xu, C. Bernecky, C. Lee, K. Maier, B. Schwalb, D. Tegunov, J. Plitzko,
H. Urlaub, P. Cramer, Nature Communications 8 (2017).
date_created: 2018-12-11T11:47:25Z
date_published: 2017-06-06T00:00:00Z
date_updated: 2021-01-12T08:05:40Z
day: '06'
ddc:
- '570'
doi: 10.1038/ncomms15741
extern: '1'
file:
- access_level: open_access
checksum: 940742282a9a285dc4aeae0c2b5ebe96
content_type: application/pdf
creator: dernst
date_created: 2019-01-21T14:48:10Z
date_updated: 2020-07-14T12:47:16Z
file_id: '5865'
file_name: 2017_NatureComm_Xu.pdf
file_size: 3018075
relation: main_file
file_date_updated: 2020-07-14T12:47:16Z
has_accepted_license: '1'
intvolume: ' 8'
language:
- iso: eng
month: '06'
oa: 1
oa_version: Published Version
publication: Nature Communications
publication_identifier:
issn:
- '20411723'
publication_status: published
publisher: Nature Publishing Group
publist_id: '7203'
quality_controlled: '1'
status: public
title: Architecture of the RNA polymerase II-Paf1C-TFIIS transcription elongation
complex
tmp:
image: /images/cc_by.png
legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
short: CC BY (4.0)
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 8
year: '2017'
...
---
_id: '6013'
abstract:
- lang: eng
text: The first hundred attoseconds of the electron dynamics during strong field
tunneling ionization are investigated. We quantify theoretically how the electron’s
classical trajectories in the continuum emerge from the tunneling process and
test the results with those achieved in parallel from attoclock measurements.
An especially high sensitivity on the tunneling barrier is accomplished here by
comparing the momentum distributions of two atomic species of slightly deviating
atomic potentials (argon and krypton) being ionized under absolutely identical
conditions with near-infrared laser pulses (1300 nm). The agreement between experiment
and theory provides clear evidence for a nonzero tunneling time delay and a nonvanishing
longitudinal momentum of the electron at the “tunnel exit.”
article_number: '023201'
author:
- first_name: Nicolas
full_name: Camus, Nicolas
last_name: Camus
- first_name: Enderalp
full_name: Yakaboylu, Enderalp
id: 38CB71F6-F248-11E8-B48F-1D18A9856A87
last_name: Yakaboylu
orcid: 0000-0001-5973-0874
- first_name: Lutz
full_name: Fechner, Lutz
last_name: Fechner
- first_name: Michael
full_name: Klaiber, Michael
last_name: Klaiber
- first_name: Martin
full_name: Laux, Martin
last_name: Laux
- first_name: Yonghao
full_name: Mi, Yonghao
last_name: Mi
- first_name: Karen Z.
full_name: Hatsagortsyan, Karen Z.
last_name: Hatsagortsyan
- first_name: Thomas
full_name: Pfeifer, Thomas
last_name: Pfeifer
- first_name: Christoph H.
full_name: Keitel, Christoph H.
last_name: Keitel
- first_name: Robert
full_name: Moshammer, Robert
last_name: Moshammer
citation:
ama: Camus N, Yakaboylu E, Fechner L, et al. Experimental evidence for quantum tunneling
time. Physical Review Letters. 2017;119(2). doi:10.1103/PhysRevLett.119.023201
apa: Camus, N., Yakaboylu, E., Fechner, L., Klaiber, M., Laux, M., Mi, Y., … Moshammer,
R. (2017). Experimental evidence for quantum tunneling time. Physical Review
Letters. American Physical Society. https://doi.org/10.1103/PhysRevLett.119.023201
chicago: Camus, Nicolas, Enderalp Yakaboylu, Lutz Fechner, Michael Klaiber, Martin
Laux, Yonghao Mi, Karen Z. Hatsagortsyan, Thomas Pfeifer, Christoph H. Keitel,
and Robert Moshammer. “Experimental Evidence for Quantum Tunneling Time.” Physical
Review Letters. American Physical Society, 2017. https://doi.org/10.1103/PhysRevLett.119.023201.
ieee: N. Camus et al., “Experimental evidence for quantum tunneling time,”
Physical Review Letters, vol. 119, no. 2. American Physical Society, 2017.
ista: Camus N, Yakaboylu E, Fechner L, Klaiber M, Laux M, Mi Y, Hatsagortsyan KZ,
Pfeifer T, Keitel CH, Moshammer R. 2017. Experimental evidence for quantum tunneling
time. Physical Review Letters. 119(2), 023201.
mla: Camus, Nicolas, et al. “Experimental Evidence for Quantum Tunneling Time.”
Physical Review Letters, vol. 119, no. 2, 023201, American Physical Society,
2017, doi:10.1103/PhysRevLett.119.023201.
short: N. Camus, E. Yakaboylu, L. Fechner, M. Klaiber, M. Laux, Y. Mi, K.Z. Hatsagortsyan,
T. Pfeifer, C.H. Keitel, R. Moshammer, Physical Review Letters 119 (2017).
date_created: 2019-02-14T15:24:13Z
date_published: 2017-07-14T00:00:00Z
date_updated: 2023-02-23T11:13:36Z
day: '14'
department:
- _id: MiLe
doi: 10.1103/PhysRevLett.119.023201
external_id:
arxiv:
- '1611.03701'
intvolume: ' 119'
issue: '2'
language:
- iso: eng
main_file_link:
- open_access: '1'
url: https://arxiv.org/abs/1611.03701
month: '07'
oa: 1
oa_version: Preprint
publication: Physical Review Letters
publication_identifier:
eissn:
- 1079-7114
issn:
- 0031-9007
publication_status: published
publisher: American Physical Society
quality_controlled: '1'
related_material:
record:
- id: '313'
relation: earlier_version
status: public
scopus_import: 1
status: public
title: Experimental evidence for quantum tunneling time
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 119
year: '2017'
...
---
_id: '603'
abstract:
- lang: eng
text: During transcription, RNA polymerase II (Pol II) associates with the conserved
elongation factor DSIF. DSIF renders the elongation complex stable and functions
during Pol II pausing and RNA processing. We combined cryo-EM and X-ray crystallography
to determine the structure of the mammalian Pol II-DSIF elongation complex at
a nominal resolution of 3.4. Human DSIF has a modular structure with two domains
forming a DNA clamp, two domains forming an RNA clamp, and one domain buttressing
the RNA clamp. The clamps maintain the transcription bubble, position upstream
DNA, and retain the RNA transcript in the exit tunnel. The mobile C-terminal region
of DSIF is located near exiting RNA, where it can recruit factors for RNA processing.
The structure provides insight into the roles of DSIF during mRNA synthesis.
article_processing_charge: No
author:
- first_name: Carrie A
full_name: Bernecky, Carrie A
id: 2CB9DFE2-F248-11E8-B48F-1D18A9856A87
last_name: Bernecky
orcid: 0000-0003-0893-7036
- first_name: Jürgen
full_name: Plitzko, Jürgen
last_name: Plitzko
- first_name: Patrick
full_name: Cramer, Patrick
last_name: Cramer
citation:
ama: Bernecky C, Plitzko J, Cramer P. Structure of a transcribing RNA polymerase
II-DSIF complex reveals a multidentate DNA-RNA clamp. Nature Structural and
Molecular Biology. 2017;24(10):809-815. doi:10.1038/nsmb.3465
apa: Bernecky, C., Plitzko, J., & Cramer, P. (2017). Structure of a transcribing
RNA polymerase II-DSIF complex reveals a multidentate DNA-RNA clamp. Nature
Structural and Molecular Biology. Nature Publishing Group. https://doi.org/10.1038/nsmb.3465
chicago: Bernecky, Carrie, Jürgen Plitzko, and Patrick Cramer. “Structure of a Transcribing
RNA Polymerase II-DSIF Complex Reveals a Multidentate DNA-RNA Clamp.” Nature
Structural and Molecular Biology. Nature Publishing Group, 2017. https://doi.org/10.1038/nsmb.3465.
ieee: C. Bernecky, J. Plitzko, and P. Cramer, “Structure of a transcribing RNA polymerase
II-DSIF complex reveals a multidentate DNA-RNA clamp,” Nature Structural and
Molecular Biology, vol. 24, no. 10. Nature Publishing Group, pp. 809–815,
2017.
ista: Bernecky C, Plitzko J, Cramer P. 2017. Structure of a transcribing RNA polymerase
II-DSIF complex reveals a multidentate DNA-RNA clamp. Nature Structural and Molecular
Biology. 24(10), 809–815.
mla: Bernecky, Carrie, et al. “Structure of a Transcribing RNA Polymerase II-DSIF
Complex Reveals a Multidentate DNA-RNA Clamp.” Nature Structural and Molecular
Biology, vol. 24, no. 10, Nature Publishing Group, 2017, pp. 809–15, doi:10.1038/nsmb.3465.
short: C. Bernecky, J. Plitzko, P. Cramer, Nature Structural and Molecular Biology
24 (2017) 809–815.
date_created: 2018-12-11T11:47:26Z
date_published: 2017-10-05T00:00:00Z
date_updated: 2021-01-12T08:05:47Z
day: '05'
doi: 10.1038/nsmb.3465
extern: '1'
intvolume: ' 24'
issue: '10'
language:
- iso: eng
month: '10'
oa_version: None
page: 809 - 815
publication: Nature Structural and Molecular Biology
publication_identifier:
issn:
- '15459993'
publication_status: published
publisher: Nature Publishing Group
publist_id: '7202'
quality_controlled: '1'
status: public
title: Structure of a transcribing RNA polymerase II-DSIF complex reveals a multidentate
DNA-RNA clamp
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 24
year: '2017'
...
---
_id: '605'
abstract:
- lang: eng
text: 'Position based cryptography (PBC), proposed in the seminal work of Chandran,
Goyal, Moriarty, and Ostrovsky (SIAM J. Computing, 2014), aims at constructing
cryptographic schemes in which the identity of the user is his geographic position.
Chandran et al. construct PBC schemes for secure positioning and position-based
key agreement in the bounded-storage model (Maurer, J. Cryptology, 1992). Apart
from bounded memory, their security proofs need a strong additional restriction
on the power of the adversary: he cannot compute joint functions of his inputs.
Removing this assumption is left as an open problem. We show that an answer to
this question would resolve a long standing open problem in multiparty communication
complexity: finding a function that is hard to compute with low communication
complexity in the simultaneous message model, but easy to compute in the fully
adaptive model. On a more positive side: we also show some implications in the
other direction, i.e.: we prove that lower bounds on the communication complexity
of certain multiparty problems imply existence of PBC primitives. Using this result
we then show two attractive ways to “bypass” our hardness result: the first uses
the random oracle model, the second weakens the locality requirement in the bounded-storage
model to online computability. The random oracle construction is arguably one
of the simplest proposed so far in this area. Our results indicate that constructing
improved provably secure protocols for PBC requires a better understanding of
multiparty communication complexity. This is yet another example where negative
results in one area (in our case: lower bounds in multiparty communication complexity)
can be used to construct secure cryptographic schemes.'
alternative_title:
- LNCS
author:
- first_name: Joshua
full_name: Brody, Joshua
last_name: Brody
- first_name: Stefan
full_name: Dziembowski, Stefan
last_name: Dziembowski
- first_name: Sebastian
full_name: Faust, Sebastian
last_name: Faust
- first_name: Krzysztof Z
full_name: Pietrzak, Krzysztof Z
id: 3E04A7AA-F248-11E8-B48F-1D18A9856A87
last_name: Pietrzak
orcid: 0000-0002-9139-1654
citation:
ama: 'Brody J, Dziembowski S, Faust S, Pietrzak KZ. Position based cryptography
and multiparty communication complexity. In: Kalai Y, Reyzin L, eds. Vol 10677.
Springer; 2017:56-81. doi:10.1007/978-3-319-70500-2_3'
apa: 'Brody, J., Dziembowski, S., Faust, S., & Pietrzak, K. Z. (2017). Position
based cryptography and multiparty communication complexity. In Y. Kalai &
L. Reyzin (Eds.) (Vol. 10677, pp. 56–81). Presented at the TCC: Theory of Cryptography
Conference, Baltimore, MD, United States: Springer. https://doi.org/10.1007/978-3-319-70500-2_3'
chicago: Brody, Joshua, Stefan Dziembowski, Sebastian Faust, and Krzysztof Z Pietrzak.
“Position Based Cryptography and Multiparty Communication Complexity.” edited
by Yael Kalai and Leonid Reyzin, 10677:56–81. Springer, 2017. https://doi.org/10.1007/978-3-319-70500-2_3.
ieee: 'J. Brody, S. Dziembowski, S. Faust, and K. Z. Pietrzak, “Position based cryptography
and multiparty communication complexity,” presented at the TCC: Theory of Cryptography
Conference, Baltimore, MD, United States, 2017, vol. 10677, pp. 56–81.'
ista: 'Brody J, Dziembowski S, Faust S, Pietrzak KZ. 2017. Position based cryptography
and multiparty communication complexity. TCC: Theory of Cryptography Conference,
LNCS, vol. 10677, 56–81.'
mla: Brody, Joshua, et al. Position Based Cryptography and Multiparty Communication
Complexity. Edited by Yael Kalai and Leonid Reyzin, vol. 10677, Springer,
2017, pp. 56–81, doi:10.1007/978-3-319-70500-2_3.
short: J. Brody, S. Dziembowski, S. Faust, K.Z. Pietrzak, in:, Y. Kalai, L. Reyzin
(Eds.), Springer, 2017, pp. 56–81.
conference:
end_date: 2017-11-15
location: Baltimore, MD, United States
name: 'TCC: Theory of Cryptography Conference'
start_date: 2017-11-12
date_created: 2018-12-11T11:47:27Z
date_published: 2017-11-05T00:00:00Z
date_updated: 2021-01-12T08:05:53Z
day: '05'
department:
- _id: KrPi
doi: 10.1007/978-3-319-70500-2_3
ec_funded: 1
editor:
- first_name: Yael
full_name: Kalai, Yael
last_name: Kalai
- first_name: Leonid
full_name: Reyzin, Leonid
last_name: Reyzin
intvolume: ' 10677'
language:
- iso: eng
main_file_link:
- open_access: '1'
url: https://eprint.iacr.org/2016/536
month: '11'
oa: 1
oa_version: Submitted Version
page: 56 - 81
project:
- _id: 258AA5B2-B435-11E9-9278-68D0E5697425
call_identifier: H2020
grant_number: '682815'
name: Teaching Old Crypto New Tricks
publication_identifier:
isbn:
- 978-331970499-9
publication_status: published
publisher: Springer
publist_id: '7200'
quality_controlled: '1'
scopus_import: 1
status: public
title: Position based cryptography and multiparty communication complexity
type: conference
user_id: 3E5EF7F0-F248-11E8-B48F-1D18A9856A87
volume: 10677
year: '2017'
...
---
_id: '604'
abstract:
- lang: eng
text: In several settings of physics and chemistry one has to deal with molecules
interacting with some kind of an external environment, be it a gas, a solution,
or a crystal surface. Understanding molecular processes in the presence of such
a many-particle bath is inherently challenging, and usually requires large-scale
numerical computations. Here, we present an alternative approach to the problem,
based on the notion of the angulon quasiparticle. We show that molecules rotating
inside superfluid helium nanodroplets and Bose–Einstein condensates form angulons,
and therefore can be described by straightforward solutions of a simple microscopic
Hamiltonian. Casting the problem in the language of angulons allows us not only
to greatly simplify it, but also to gain insights into the origins of the observed
phenomena and to make predictions for future experimental studies.
alternative_title:
- Theoretical and Computational Chemistry Series
author:
- first_name: Mikhail
full_name: Lemeshko, Mikhail
id: 37CB05FA-F248-11E8-B48F-1D18A9856A87
last_name: Lemeshko
orcid: 0000-0002-6990-7802
- first_name: Richard
full_name: Schmidt, Richard
last_name: Schmidt
citation:
ama: 'Lemeshko M, Schmidt R. Molecular impurities interacting with a many-particle
environment: From ultracold gases to helium nanodroplets. In: Dulieu O, Osterwalder
A, eds. Cold Chemistry: Molecular Scattering and Reactivity Near Absolute Zero
. Vol 11. Theoretical and Computational Chemistry Series. The Royal Society
of Chemistry; 2017:444-495. doi:10.1039/9781782626800-00444'
apa: 'Lemeshko, M., & Schmidt, R. (2017). Molecular impurities interacting with
a many-particle environment: From ultracold gases to helium nanodroplets. In O.
Dulieu & A. Osterwalder (Eds.), Cold Chemistry: Molecular Scattering and
Reactivity Near Absolute Zero (Vol. 11, pp. 444–495). The Royal Society of
Chemistry. https://doi.org/10.1039/9781782626800-00444'
chicago: 'Lemeshko, Mikhail, and Richard Schmidt. “Molecular Impurities Interacting
with a Many-Particle Environment: From Ultracold Gases to Helium Nanodroplets.”
In Cold Chemistry: Molecular Scattering and Reactivity Near Absolute Zero ,
edited by Oliver Dulieu and Andreas Osterwalder, 11:444–95. Theoretical and Computational
Chemistry Series. The Royal Society of Chemistry, 2017. https://doi.org/10.1039/9781782626800-00444.'
ieee: 'M. Lemeshko and R. Schmidt, “Molecular impurities interacting with a many-particle
environment: From ultracold gases to helium nanodroplets,” in Cold Chemistry:
Molecular Scattering and Reactivity Near Absolute Zero , vol. 11, O. Dulieu
and A. Osterwalder, Eds. The Royal Society of Chemistry, 2017, pp. 444–495.'
ista: 'Lemeshko M, Schmidt R. 2017.Molecular impurities interacting with a many-particle
environment: From ultracold gases to helium nanodroplets. In: Cold Chemistry:
Molecular Scattering and Reactivity Near Absolute Zero . Theoretical and Computational
Chemistry Series, vol. 11, 444–495.'
mla: 'Lemeshko, Mikhail, and Richard Schmidt. “Molecular Impurities Interacting
with a Many-Particle Environment: From Ultracold Gases to Helium Nanodroplets.”
Cold Chemistry: Molecular Scattering and Reactivity Near Absolute Zero ,
edited by Oliver Dulieu and Andreas Osterwalder, vol. 11, The Royal Society of
Chemistry, 2017, pp. 444–95, doi:10.1039/9781782626800-00444.'
short: 'M. Lemeshko, R. Schmidt, in:, O. Dulieu, A. Osterwalder (Eds.), Cold Chemistry:
Molecular Scattering and Reactivity Near Absolute Zero , The Royal Society of
Chemistry, 2017, pp. 444–495.'
date_created: 2018-12-11T11:47:27Z
date_published: 2017-12-14T00:00:00Z
date_updated: 2021-01-12T08:05:50Z
day: '14'
department:
- _id: MiLe
doi: 10.1039/9781782626800-00444
editor:
- first_name: Oliver
full_name: Dulieu, Oliver
last_name: Dulieu
- first_name: Andreas
full_name: Osterwalder, Andreas
last_name: Osterwalder
intvolume: ' 11'
language:
- iso: eng
main_file_link:
- open_access: '1'
url: https://arxiv.org/abs/1703.06753
month: '12'
oa: 1
oa_version: Submitted Version
page: 444 - 495
publication: 'Cold Chemistry: Molecular Scattering and Reactivity Near Absolute Zero '
publication_identifier:
issn:
- '20413181'
publication_status: published
publisher: The Royal Society of Chemistry
publist_id: '7201'
quality_controlled: '1'
scopus_import: 1
series_title: Theoretical and Computational Chemistry Series
status: public
title: 'Molecular impurities interacting with a many-particle environment: From ultracold
gases to helium nanodroplets'
type: book_chapter
user_id: 4435EBFC-F248-11E8-B48F-1D18A9856A87
volume: 11
year: '2017'
...
---
_id: '6059'
abstract:
- lang: eng
text: Neutrophils or polymorphonuclear cells (PMN) eliminate bacteria via phagocytosis
and/or NETosis. Apartfrom these conventional roles, PMN also have immune-regulatory
functions. They can transdifferentiateand upregulate MHCII as well as ligands
for costimulatory receptors which enables them to behave asantigen presenting
cells (APC). The initial step for activating T-cells is the formation of an immunesynapse
between T-cells and antigen-presenting cells. However, the immune synapse that
develops atthe PMN/T-cell contact zone is as yet hardly investigated due to the
non-availability of methods foranalysis of large number of PMN interactions. In
order to overcome these obstacles, we introduce herea workflow to analyse the
immune synapse of primary human PMN and T-cells using multispectral imag-ing flow
cytometry (InFlow microscopy) and super-resolution microscopy. For that purpose,
we used CD3and CD66b as the lineage markers for T-cells and PMN, respectively.
Thereafter, we applied and criticallydiscussed various ‘‘masks” for identification
of T-cell PMN interactions. Using this approach, we foundthat a small fraction
of transdifferentiated PMN (CD66b+CD86high) formed stable PMN/T-cell conjugates.Interestingly,
while both CD3 and CD66b accumulation in the immune synapse was dependent on thematuration
state of the PMN, only CD3 accumulation was greatly enhanced by the presence of
superanti-gen. The actin cytoskeleton was weakly rearranged at the PMN side on
the immune synapse upon contactwith a T-cell in the presence of superantigen.
A more detailed analysis using super-resolution microscopy(structured-illumination
microscopy, SIM) confirmed this finding. Together, we present an InFlow micro-scopy
based approach for the large scale analysis of PMN/T-cell interactions and – combined
with SIM – apossibility for an in-depth analysis of protein translocation at the
site of interactions.
author:
- first_name: Emre
full_name: Balta, Emre
last_name: Balta
- first_name: Julian A
full_name: Stopp, Julian A
id: 489E3F00-F248-11E8-B48F-1D18A9856A87
last_name: Stopp
- first_name: Laura
full_name: Castelletti, Laura
last_name: Castelletti
- first_name: Henning
full_name: Kirchgessner, Henning
last_name: Kirchgessner
- first_name: Yvonne
full_name: Samstag, Yvonne
last_name: Samstag
- first_name: Guido H.
full_name: Wabnitz, Guido H.
last_name: Wabnitz
citation:
ama: Balta E, Stopp JA, Castelletti L, Kirchgessner H, Samstag Y, Wabnitz GH. Qualitative
and quantitative analysis of PMN/T-cell interactions by InFlow and super-resolution
microscopy. Methods. 2017;112(1):25-38. doi:10.1016/j.ymeth.2016.09.013
apa: Balta, E., Stopp, J. A., Castelletti, L., Kirchgessner, H., Samstag, Y., &
Wabnitz, G. H. (2017). Qualitative and quantitative analysis of PMN/T-cell interactions
by InFlow and super-resolution microscopy. Methods. Elsevier. https://doi.org/10.1016/j.ymeth.2016.09.013
chicago: Balta, Emre, Julian A Stopp, Laura Castelletti, Henning Kirchgessner, Yvonne
Samstag, and Guido H. Wabnitz. “Qualitative and Quantitative Analysis of PMN/T-Cell
Interactions by InFlow and Super-Resolution Microscopy.” Methods. Elsevier,
2017. https://doi.org/10.1016/j.ymeth.2016.09.013.
ieee: E. Balta, J. A. Stopp, L. Castelletti, H. Kirchgessner, Y. Samstag, and G.
H. Wabnitz, “Qualitative and quantitative analysis of PMN/T-cell interactions
by InFlow and super-resolution microscopy,” Methods, vol. 112, no. 1. Elsevier,
pp. 25–38, 2017.
ista: Balta E, Stopp JA, Castelletti L, Kirchgessner H, Samstag Y, Wabnitz GH. 2017.
Qualitative and quantitative analysis of PMN/T-cell interactions by InFlow and
super-resolution microscopy. Methods. 112(1), 25–38.
mla: Balta, Emre, et al. “Qualitative and Quantitative Analysis of PMN/T-Cell Interactions
by InFlow and Super-Resolution Microscopy.” Methods, vol. 112, no. 1, Elsevier,
2017, pp. 25–38, doi:10.1016/j.ymeth.2016.09.013.
short: E. Balta, J.A. Stopp, L. Castelletti, H. Kirchgessner, Y. Samstag, G.H. Wabnitz,
Methods 112 (2017) 25–38.
date_created: 2019-02-26T13:45:17Z
date_published: 2017-01-01T00:00:00Z
date_updated: 2021-01-12T08:05:57Z
day: '01'
doi: 10.1016/j.ymeth.2016.09.013
extern: '1'
external_id:
pmid:
- '27693880'
intvolume: ' 112'
issue: '1'
language:
- iso: eng
month: '01'
oa_version: None
page: 25-38
pmid: 1
publication: Methods
publication_identifier:
issn:
- 1046-2023
publication_status: published
publisher: Elsevier
quality_controlled: '1'
related_material:
link:
- relation: supplementary_material
url: http://dx.doi.org/10.1016/j.ymeth.2016.09.013
status: public
title: Qualitative and quantitative analysis of PMN/T-cell interactions by InFlow
and super-resolution microscopy
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 112
year: '2017'
...
---
_id: '609'
abstract:
- lang: eng
text: Several cryptographic schemes and applications are based on functions that
are both reasonably efficient to compute and moderately hard to invert, including
client puzzles for Denial-of-Service protection, password protection via salted
hashes, or recent proof-of-work blockchain systems. Despite their wide use, a
definition of this concept has not yet been distilled and formalized explicitly.
Instead, either the applications are proven directly based on the assumptions
underlying the function, or some property of the function is proven, but the security
of the application is argued only informally. The goal of this work is to provide
a (universal) definition that decouples the efforts of designing new moderately
hard functions and of building protocols based on them, serving as an interface
between the two. On a technical level, beyond the mentioned definitions, we instantiate
the model for four different notions of hardness. We extend the work of Alwen
and Serbinenko (STOC 2015) by providing a general tool for proving security for
the first notion of memory-hard functions that allows for provably secure applications.
The tool allows us to recover all of the graph-theoretic techniques developed
for proving security under the older, non-composable, notion of security used
by Alwen and Serbinenko. As an application of our definition of moderately hard
functions, we prove the security of two different schemes for proofs of effort
(PoE). We also formalize and instantiate the concept of a non-interactive proof
of effort (niPoE), in which the proof is not bound to a particular communication
context but rather any bit-string chosen by the prover.
alternative_title:
- LNCS
author:
- first_name: Joel F
full_name: Alwen, Joel F
id: 2A8DFA8C-F248-11E8-B48F-1D18A9856A87
last_name: Alwen
- first_name: Björn
full_name: Tackmann, Björn
last_name: Tackmann
citation:
ama: 'Alwen JF, Tackmann B. Moderately hard functions: Definition, instantiations,
and applications. In: Kalai Y, Reyzin L, eds. Vol 10677. Springer; 2017:493-526.
doi:10.1007/978-3-319-70500-2_17'
apa: 'Alwen, J. F., & Tackmann, B. (2017). Moderately hard functions: Definition,
instantiations, and applications. In Y. Kalai & L. Reyzin (Eds.) (Vol. 10677,
pp. 493–526). Presented at the TCC: Theory of Cryptography, Baltimore, MD, United
States: Springer. https://doi.org/10.1007/978-3-319-70500-2_17'
chicago: 'Alwen, Joel F, and Björn Tackmann. “Moderately Hard Functions: Definition,
Instantiations, and Applications.” edited by Yael Kalai and Leonid Reyzin, 10677:493–526.
Springer, 2017. https://doi.org/10.1007/978-3-319-70500-2_17.'
ieee: 'J. F. Alwen and B. Tackmann, “Moderately hard functions: Definition, instantiations,
and applications,” presented at the TCC: Theory of Cryptography, Baltimore, MD,
United States, 2017, vol. 10677, pp. 493–526.'
ista: 'Alwen JF, Tackmann B. 2017. Moderately hard functions: Definition, instantiations,
and applications. TCC: Theory of Cryptography, LNCS, vol. 10677, 493–526.'
mla: 'Alwen, Joel F., and Björn Tackmann. Moderately Hard Functions: Definition,
Instantiations, and Applications. Edited by Yael Kalai and Leonid Reyzin,
vol. 10677, Springer, 2017, pp. 493–526, doi:10.1007/978-3-319-70500-2_17.'
short: J.F. Alwen, B. Tackmann, in:, Y. Kalai, L. Reyzin (Eds.), Springer, 2017,
pp. 493–526.
conference:
end_date: 2017-11-15
location: Baltimore, MD, United States
name: 'TCC: Theory of Cryptography'
start_date: 2017-11-12
date_created: 2018-12-11T11:47:28Z
date_published: 2017-11-05T00:00:00Z
date_updated: 2021-01-12T08:06:04Z
day: '05'
department:
- _id: KrPi
doi: 10.1007/978-3-319-70500-2_17
editor:
- first_name: Yael
full_name: Kalai, Yael
last_name: Kalai
- first_name: Leonid
full_name: Reyzin, Leonid
last_name: Reyzin
intvolume: ' 10677'
language:
- iso: eng
main_file_link:
- open_access: '1'
url: https://eprint.iacr.org/2017/945
month: '11'
oa: 1
oa_version: Submitted Version
page: 493 - 526
publication_identifier:
isbn:
- 978-331970499-9
publication_status: published
publisher: Springer
publist_id: '7196'
quality_controlled: '1'
scopus_import: 1
status: public
title: 'Moderately hard functions: Definition, instantiations, and applications'
type: conference
user_id: 3E5EF7F0-F248-11E8-B48F-1D18A9856A87
volume: 10677
year: '2017'
...
---
_id: '610'
abstract:
- lang: eng
text: 'The fact that the complete graph K5 does not embed in the plane has been
generalized in two independent directions. On the one hand, the solution of the
classical Heawood problem for graphs on surfaces established that the complete
graph Kn embeds in a closed surface M (other than the Klein bottle) if and only
if (n−3)(n−4) ≤ 6b1(M), where b1(M) is the first Z2-Betti number of M. On the
other hand, van Kampen and Flores proved that the k-skeleton of the n-dimensional
simplex (the higher-dimensional analogue of Kn+1) embeds in R2k if and only if
n ≤ 2k + 1. Two decades ago, Kühnel conjectured that the k-skeleton of the n-simplex
embeds in a compact, (k − 1)-connected 2k-manifold with kth Z2-Betti number bk
only if the following generalized Heawood inequality holds: (k+1 n−k−1) ≤ (k+1
2k+1)bk. This is a common generalization of the case of graphs on surfaces as
well as the van Kampen–Flores theorem. In the spirit of Kühnel’s conjecture, we
prove that if the k-skeleton of the n-simplex embeds in a compact 2k-manifold
with kth Z2-Betti number bk, then n ≤ 2bk(k 2k+2)+2k+4. This bound is weaker than
the generalized Heawood inequality, but does not require the assumption that M
is (k−1)-connected. Our results generalize to maps without q-covered points, in
the spirit of Tverberg’s theorem, for q a prime power. Our proof uses a result
of Volovikov about maps that satisfy a certain homological triviality condition.'
acknowledgement: The work by Z. P. was partially supported by the Israel Science Foundation
grant ISF-768/12. The work by Z. P. and M. T. was partially supported by the project
CE-ITI (GACR P202/12/G061) of the Czech Science Foundation and by the ERC Advanced
Grant No. 267165. Part of the research work of M.T. was conducted at IST Austria,
supported by an IST Fellowship. The research of P. P. was supported by the ERC Advanced
grant no. 320924. The work by I. M. and U. W. was supported by the Swiss National
Science Foundation (grants SNSF-200020-138230 and SNSF-PP00P2-138948). The collaboration
between U. W. and X. G. was partially supported by the LabEx Bézout (ANR-10-LABX-58).
author:
- first_name: Xavier
full_name: Goaoc, Xavier
last_name: Goaoc
- first_name: Isaac
full_name: Mabillard, Isaac
id: 32BF9DAA-F248-11E8-B48F-1D18A9856A87
last_name: Mabillard
- first_name: Pavel
full_name: Paták, Pavel
last_name: Paták
- first_name: Zuzana
full_name: Patakova, Zuzana
id: 48B57058-F248-11E8-B48F-1D18A9856A87
last_name: Patakova
orcid: 0000-0002-3975-1683
- first_name: Martin
full_name: Tancer, Martin
id: 38AC689C-F248-11E8-B48F-1D18A9856A87
last_name: Tancer
orcid: 0000-0002-1191-6714
- first_name: Uli
full_name: Wagner, Uli
id: 36690CA2-F248-11E8-B48F-1D18A9856A87
last_name: Wagner
orcid: 0000-0002-1494-0568
citation:
ama: 'Goaoc X, Mabillard I, Paták P, Patakova Z, Tancer M, Wagner U. On generalized
Heawood inequalities for manifolds: A van Kampen–Flores type nonembeddability
result. Israel Journal of Mathematics. 2017;222(2):841-866. doi:10.1007/s11856-017-1607-7'
apa: 'Goaoc, X., Mabillard, I., Paták, P., Patakova, Z., Tancer, M., & Wagner,
U. (2017). On generalized Heawood inequalities for manifolds: A van Kampen–Flores
type nonembeddability result. Israel Journal of Mathematics. Springer.
https://doi.org/10.1007/s11856-017-1607-7'
chicago: 'Goaoc, Xavier, Isaac Mabillard, Pavel Paták, Zuzana Patakova, Martin Tancer,
and Uli Wagner. “On Generalized Heawood Inequalities for Manifolds: A van Kampen–Flores
Type Nonembeddability Result.” Israel Journal of Mathematics. Springer,
2017. https://doi.org/10.1007/s11856-017-1607-7.'
ieee: 'X. Goaoc, I. Mabillard, P. Paták, Z. Patakova, M. Tancer, and U. Wagner,
“On generalized Heawood inequalities for manifolds: A van Kampen–Flores type nonembeddability
result,” Israel Journal of Mathematics, vol. 222, no. 2. Springer, pp.
841–866, 2017.'
ista: 'Goaoc X, Mabillard I, Paták P, Patakova Z, Tancer M, Wagner U. 2017. On generalized
Heawood inequalities for manifolds: A van Kampen–Flores type nonembeddability
result. Israel Journal of Mathematics. 222(2), 841–866.'
mla: 'Goaoc, Xavier, et al. “On Generalized Heawood Inequalities for Manifolds:
A van Kampen–Flores Type Nonembeddability Result.” Israel Journal of Mathematics,
vol. 222, no. 2, Springer, 2017, pp. 841–66, doi:10.1007/s11856-017-1607-7.'
short: X. Goaoc, I. Mabillard, P. Paták, Z. Patakova, M. Tancer, U. Wagner, Israel
Journal of Mathematics 222 (2017) 841–866.
date_created: 2018-12-11T11:47:29Z
date_published: 2017-10-01T00:00:00Z
date_updated: 2023-02-23T10:02:13Z
day: '01'
department:
- _id: UlWa
doi: 10.1007/s11856-017-1607-7
ec_funded: 1
intvolume: ' 222'
issue: '2'
language:
- iso: eng
main_file_link:
- open_access: '1'
url: https://arxiv.org/abs/1610.09063
month: '10'
oa: 1
oa_version: Preprint
page: 841 - 866
project:
- _id: 25681D80-B435-11E9-9278-68D0E5697425
call_identifier: FP7
grant_number: '291734'
name: International IST Postdoc Fellowship Programme
publication: Israel Journal of Mathematics
publication_status: published
publisher: Springer
publist_id: '7194'
quality_controlled: '1'
related_material:
record:
- id: '1511'
relation: earlier_version
status: public
scopus_import: 1
status: public
title: 'On generalized Heawood inequalities for manifolds: A van Kampen–Flores type
nonembeddability result'
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 222
year: '2017'
...
---
_id: '6115'
abstract:
- lang: eng
text: Animals adjust their behavioral priorities according to momentary needs and
prior experience. We show that Caenorhabditis elegans changes how it processes
sensory information according to the oxygen environment it experienced recently.
C. elegans acclimated to 7% O2 are aroused by CO2 and repelled by pheromones that
attract animals acclimated to 21% O2. This behavioral plasticity arises from prolonged
activity differences in a circuit that continuously signals O2 levels. A sustained
change in the activity of O2-sensing neurons reprograms the properties of their
postsynaptic partners, the RMG hub interneurons. RMG is gap-junctionally coupled
to the ASK and ADL pheromone sensors that respectively drive pheromone attraction
and repulsion. Prior O2 experience has opposite effects on the pheromone responsiveness
of these neurons. These circuit changes provide a physiological correlate of altered
pheromone valence. Our results suggest C. elegans stores a memory of recent O2
experience in the RMG circuit and illustrate how a circuit is flexibly sculpted
to guide behavioral decisions in a context-dependent manner.
author:
- first_name: Lorenz A.
full_name: Fenk, Lorenz A.
last_name: Fenk
- first_name: Mario
full_name: de Bono, Mario
id: 4E3FF80E-F248-11E8-B48F-1D18A9856A87
last_name: de Bono
orcid: 0000-0001-8347-0443
citation:
ama: Fenk LA, de Bono M. Memory of recent oxygen experience switches pheromone valence
inCaenorhabditis elegans. Proceedings of the National Academy of Sciences.
2017;114(16):4195-4200. doi:10.1073/pnas.1618934114
apa: Fenk, L. A., & de Bono, M. (2017). Memory of recent oxygen experience switches
pheromone valence inCaenorhabditis elegans. Proceedings of the National Academy
of Sciences. National Academy of Sciences. https://doi.org/10.1073/pnas.1618934114
chicago: Fenk, Lorenz A., and Mario de Bono. “Memory of Recent Oxygen Experience
Switches Pheromone Valence InCaenorhabditis Elegans.” Proceedings of the National
Academy of Sciences. National Academy of Sciences, 2017. https://doi.org/10.1073/pnas.1618934114.
ieee: L. A. Fenk and M. de Bono, “Memory of recent oxygen experience switches pheromone
valence inCaenorhabditis elegans,” Proceedings of the National Academy of Sciences,
vol. 114, no. 16. National Academy of Sciences, pp. 4195–4200, 2017.
ista: Fenk LA, de Bono M. 2017. Memory of recent oxygen experience switches pheromone
valence inCaenorhabditis elegans. Proceedings of the National Academy of Sciences.
114(16), 4195–4200.
mla: Fenk, Lorenz A., and Mario de Bono. “Memory of Recent Oxygen Experience Switches
Pheromone Valence InCaenorhabditis Elegans.” Proceedings of the National Academy
of Sciences, vol. 114, no. 16, National Academy of Sciences, 2017, pp. 4195–200,
doi:10.1073/pnas.1618934114.
short: L.A. Fenk, M. de Bono, Proceedings of the National Academy of Sciences 114
(2017) 4195–4200.
date_created: 2019-03-19T13:46:36Z
date_published: 2017-04-18T00:00:00Z
date_updated: 2021-01-12T08:06:11Z
day: '18'
ddc:
- '570'
doi: 10.1073/pnas.1618934114
extern: '1'
external_id:
pmid:
- '28373553'
file:
- access_level: open_access
checksum: 1801bc8319b752fa17598004ec375279
content_type: application/pdf
creator: kschuh
date_created: 2019-03-19T14:00:42Z
date_updated: 2020-07-14T12:47:20Z
file_id: '6116'
file_name: 2017_PNAS_Fenk.pdf
file_size: 1217696
relation: main_file
file_date_updated: 2020-07-14T12:47:20Z
has_accepted_license: '1'
intvolume: ' 114'
issue: '16'
language:
- iso: eng
month: '04'
oa: 1
oa_version: Published Version
page: 4195-4200
pmid: 1
publication: Proceedings of the National Academy of Sciences
publication_identifier:
issn:
- 0027-8424
- 1091-6490
publication_status: published
publisher: National Academy of Sciences
quality_controlled: '1'
status: public
title: Memory of recent oxygen experience switches pheromone valence inCaenorhabditis
elegans
type: journal_article
user_id: 3E5EF7F0-F248-11E8-B48F-1D18A9856A87
volume: 114
year: '2017'
...
---
_id: '6117'
abstract:
- lang: eng
text: 'Interleukin-17 (IL-17) is a major pro-inflammatory cytokine: it mediates
responses to pathogens or tissue damage, and drives autoimmune diseases. Little
is known about its role in the nervous system. Here we show that IL-17 has neuromodulator-like
properties in Caenorhabditis elegans. IL-17 can act directly on neurons to alter
their response properties and contribution to behaviour. Using unbiased genetic
screens, we delineate an IL-17 signalling pathway and show that it acts in the
RMG hub interneurons. Disrupting IL-17 signalling reduces RMG responsiveness to
input from oxygen sensors, and renders sustained escape from 21% oxygen transient
and contingent on additional stimuli. Over-activating IL-17 receptors abnormally
heightens responses to 21% oxygen in RMG neurons and whole animals. IL-17 deficiency
can be bypassed by optogenetic stimulation of RMG. Inducing IL-17 expression in
adults can rescue mutant defects within 6 h. These findings reveal a non-immunological
role of IL-17 modulating circuit function and behaviour.'
author:
- first_name: Changchun
full_name: Chen, Changchun
last_name: Chen
- first_name: Eisuke
full_name: Itakura, Eisuke
last_name: Itakura
- first_name: Geoffrey M.
full_name: Nelson, Geoffrey M.
last_name: Nelson
- first_name: Ming
full_name: Sheng, Ming
last_name: Sheng
- first_name: Patrick
full_name: Laurent, Patrick
last_name: Laurent
- first_name: Lorenz A.
full_name: Fenk, Lorenz A.
last_name: Fenk
- first_name: Rebecca A.
full_name: Butcher, Rebecca A.
last_name: Butcher
- first_name: Ramanujan S.
full_name: Hegde, Ramanujan S.
last_name: Hegde
- first_name: Mario
full_name: de Bono, Mario
id: 4E3FF80E-F248-11E8-B48F-1D18A9856A87
last_name: de Bono
orcid: 0000-0001-8347-0443
citation:
ama: Chen C, Itakura E, Nelson GM, et al. IL-17 is a neuromodulator of Caenorhabditis
elegans sensory responses. Nature. 2017;542(7639):43-48. doi:10.1038/nature20818
apa: Chen, C., Itakura, E., Nelson, G. M., Sheng, M., Laurent, P., Fenk, L. A.,
… de Bono, M. (2017). IL-17 is a neuromodulator of Caenorhabditis elegans sensory
responses. Nature. Springer Nature. https://doi.org/10.1038/nature20818
chicago: Chen, Changchun, Eisuke Itakura, Geoffrey M. Nelson, Ming Sheng, Patrick
Laurent, Lorenz A. Fenk, Rebecca A. Butcher, Ramanujan S. Hegde, and Mario de
Bono. “IL-17 Is a Neuromodulator of Caenorhabditis Elegans Sensory Responses.”
Nature. Springer Nature, 2017. https://doi.org/10.1038/nature20818.
ieee: C. Chen et al., “IL-17 is a neuromodulator of Caenorhabditis elegans
sensory responses,” Nature, vol. 542, no. 7639. Springer Nature, pp. 43–48,
2017.
ista: Chen C, Itakura E, Nelson GM, Sheng M, Laurent P, Fenk LA, Butcher RA, Hegde
RS, de Bono M. 2017. IL-17 is a neuromodulator of Caenorhabditis elegans sensory
responses. Nature. 542(7639), 43–48.
mla: Chen, Changchun, et al. “IL-17 Is a Neuromodulator of Caenorhabditis Elegans
Sensory Responses.” Nature, vol. 542, no. 7639, Springer Nature, 2017,
pp. 43–48, doi:10.1038/nature20818.
short: C. Chen, E. Itakura, G.M. Nelson, M. Sheng, P. Laurent, L.A. Fenk, R.A. Butcher,
R.S. Hegde, M. de Bono, Nature 542 (2017) 43–48.
date_created: 2019-03-19T14:06:41Z
date_published: 2017-02-02T00:00:00Z
date_updated: 2021-01-12T08:06:12Z
day: '02'
doi: 10.1038/nature20818
extern: '1'
external_id:
pmid:
- ' 28099418'
intvolume: ' 542'
issue: '7639'
language:
- iso: eng
main_file_link:
- open_access: '1'
url: https://www.ncbi.nlm.nih.gov/pubmed/28099418
month: '02'
oa: 1
oa_version: Submitted Version
page: 43-48
pmid: 1
publication: Nature
publication_identifier:
issn:
- 0028-0836
- 1476-4687
publication_status: published
publisher: Springer Nature
quality_controlled: '1'
status: public
title: IL-17 is a neuromodulator of Caenorhabditis elegans sensory responses
type: journal_article
user_id: 3E5EF7F0-F248-11E8-B48F-1D18A9856A87
volume: 542
year: '2017'
...
---
_id: '611'
abstract:
- lang: eng
text: Small RNAs (sRNAs) regulate genes in plants and animals. Here, we show that
population-wide differences in color patterns in snapdragon flowers are caused
by an inverted duplication that generates sRNAs. The complexity and size of the
transcripts indicate that the duplication represents an intermediate on the pathway
to microRNA evolution. The sRNAs repress a pigment biosynthesis gene, creating
a yellow highlight at the site of pollinator entry. The inverted duplication exhibits
steep clines in allele frequency in a natural hybrid zone, showing that the allele
is under selection. Thus, regulatory interactions of evolutionarily recent sRNAs
can be acted upon by selection and contribute to the evolution of phenotypic diversity.
author:
- first_name: Desmond
full_name: Bradley, Desmond
last_name: Bradley
- first_name: Ping
full_name: Xu, Ping
last_name: Xu
- first_name: Irina
full_name: Mohorianu, Irina
last_name: Mohorianu
- first_name: Annabel
full_name: Whibley, Annabel
last_name: Whibley
- first_name: David
full_name: Field, David
id: 419049E2-F248-11E8-B48F-1D18A9856A87
last_name: Field
orcid: 0000-0002-4014-8478
- first_name: Hugo
full_name: Tavares, Hugo
last_name: Tavares
- first_name: Matthew
full_name: Couchman, Matthew
last_name: Couchman
- first_name: Lucy
full_name: Copsey, Lucy
last_name: Copsey
- first_name: Rosemary
full_name: Carpenter, Rosemary
last_name: Carpenter
- first_name: Miaomiao
full_name: Li, Miaomiao
last_name: Li
- first_name: Qun
full_name: Li, Qun
last_name: Li
- first_name: Yongbiao
full_name: Xue, Yongbiao
last_name: Xue
- first_name: Tamas
full_name: Dalmay, Tamas
last_name: Dalmay
- first_name: Enrico
full_name: Coen, Enrico
last_name: Coen
citation:
ama: Bradley D, Xu P, Mohorianu I, et al. Evolution of flower color pattern through
selection on regulatory small RNAs. Science. 2017;358(6365):925-928. doi:10.1126/science.aao3526
apa: Bradley, D., Xu, P., Mohorianu, I., Whibley, A., Field, D., Tavares, H., …
Coen, E. (2017). Evolution of flower color pattern through selection on regulatory
small RNAs. Science. American Association for the Advancement of Science.
https://doi.org/10.1126/science.aao3526
chicago: Bradley, Desmond, Ping Xu, Irina Mohorianu, Annabel Whibley, David Field,
Hugo Tavares, Matthew Couchman, et al. “Evolution of Flower Color Pattern through
Selection on Regulatory Small RNAs.” Science. American Association for
the Advancement of Science, 2017. https://doi.org/10.1126/science.aao3526.
ieee: D. Bradley et al., “Evolution of flower color pattern through selection
on regulatory small RNAs,” Science, vol. 358, no. 6365. American Association
for the Advancement of Science, pp. 925–928, 2017.
ista: Bradley D, Xu P, Mohorianu I, Whibley A, Field D, Tavares H, Couchman M, Copsey
L, Carpenter R, Li M, Li Q, Xue Y, Dalmay T, Coen E. 2017. Evolution of flower
color pattern through selection on regulatory small RNAs. Science. 358(6365),
925–928.
mla: Bradley, Desmond, et al. “Evolution of Flower Color Pattern through Selection
on Regulatory Small RNAs.” Science, vol. 358, no. 6365, American Association
for the Advancement of Science, 2017, pp. 925–28, doi:10.1126/science.aao3526.
short: D. Bradley, P. Xu, I. Mohorianu, A. Whibley, D. Field, H. Tavares, M. Couchman,
L. Copsey, R. Carpenter, M. Li, Q. Li, Y. Xue, T. Dalmay, E. Coen, Science 358
(2017) 925–928.
date_created: 2018-12-11T11:47:29Z
date_published: 2017-11-17T00:00:00Z
date_updated: 2021-01-12T08:06:10Z
day: '17'
department:
- _id: NiBa
doi: 10.1126/science.aao3526
intvolume: ' 358'
issue: '6365'
language:
- iso: eng
month: '11'
oa_version: None
page: 925 - 928
publication: Science
publication_identifier:
issn:
- '00368075'
publication_status: published
publisher: American Association for the Advancement of Science
publist_id: '7193'
quality_controlled: '1'
scopus_import: 1
status: public
title: Evolution of flower color pattern through selection on regulatory small RNAs
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 358
year: '2017'
...
---
_id: '6113'
author:
- first_name: Shigekazu
full_name: Oda, Shigekazu
last_name: Oda
- first_name: Yu
full_name: Toyoshima, Yu
last_name: Toyoshima
- first_name: Mario
full_name: de Bono, Mario
id: 4E3FF80E-F248-11E8-B48F-1D18A9856A87
last_name: de Bono
orcid: 0000-0001-8347-0443
citation:
ama: Oda S, Toyoshima Y, de Bono M. Modulation of sensory information processing
by a neuroglobin in Caenorhabditis elegans. Proceedings of the National Academy
of Sciences. 2017;114(23):E4658-E4665. doi:10.1073/pnas.1614596114
apa: Oda, S., Toyoshima, Y., & de Bono, M. (2017). Modulation of sensory information
processing by a neuroglobin in Caenorhabditis elegans. Proceedings of the National
Academy of Sciences. National Academy of Sciences. https://doi.org/10.1073/pnas.1614596114
chicago: Oda, Shigekazu, Yu Toyoshima, and Mario de Bono. “Modulation of Sensory
Information Processing by a Neuroglobin in Caenorhabditis Elegans.” Proceedings
of the National Academy of Sciences. National Academy of Sciences, 2017. https://doi.org/10.1073/pnas.1614596114.
ieee: S. Oda, Y. Toyoshima, and M. de Bono, “Modulation of sensory information processing
by a neuroglobin in Caenorhabditis elegans,” Proceedings of the National Academy
of Sciences, vol. 114, no. 23. National Academy of Sciences, pp. E4658–E4665,
2017.
ista: Oda S, Toyoshima Y, de Bono M. 2017. Modulation of sensory information processing
by a neuroglobin in Caenorhabditis elegans. Proceedings of the National Academy
of Sciences. 114(23), E4658–E4665.
mla: Oda, Shigekazu, et al. “Modulation of Sensory Information Processing by a Neuroglobin
in Caenorhabditis Elegans.” Proceedings of the National Academy of Sciences,
vol. 114, no. 23, National Academy of Sciences, 2017, pp. E4658–65, doi:10.1073/pnas.1614596114.
short: S. Oda, Y. Toyoshima, M. de Bono, Proceedings of the National Academy of
Sciences 114 (2017) E4658–E4665.
date_created: 2019-03-19T13:29:51Z
date_published: 2017-06-06T00:00:00Z
date_updated: 2021-01-12T08:06:11Z
day: '06'
ddc:
- '570'
doi: 10.1073/pnas.1614596114
extern: '1'
external_id:
pmid:
- '28536200'
file:
- access_level: open_access
checksum: 9e42ce47090ecdad7d76f2dbdebb924e
content_type: application/pdf
creator: kschuh
date_created: 2019-03-19T13:42:58Z
date_updated: 2020-07-14T12:47:19Z
file_id: '6114'
file_name: 2017_PNAS_Oda.pdf
file_size: 1469622
relation: main_file
file_date_updated: 2020-07-14T12:47:19Z
has_accepted_license: '1'
intvolume: ' 114'
issue: '23'
language:
- iso: eng
month: '06'
oa: 1
oa_version: Published Version
page: E4658-E4665
pmid: 1
publication: Proceedings of the National Academy of Sciences
publication_identifier:
issn:
- 0027-8424
- 1091-6490
publication_status: published
publisher: National Academy of Sciences
quality_controlled: '1'
status: public
title: Modulation of sensory information processing by a neuroglobin in Caenorhabditis
elegans
type: journal_article
user_id: 3E5EF7F0-F248-11E8-B48F-1D18A9856A87
volume: 114
year: '2017'
...
---
_id: '613'
abstract:
- lang: eng
text: 'Bacteria in groups vary individually, and interact with other bacteria and
the environment to produce population-level patterns of gene expression. Investigating
such behavior in detail requires measuring and controlling populations at the
single-cell level alongside precisely specified interactions and environmental
characteristics. Here we present an automated, programmable platform that combines
image-based gene expression and growth measurements with on-line optogenetic expression
control for hundreds of individual Escherichia coli cells over days, in a dynamically
adjustable environment. This integrated platform broadly enables experiments that
bridge individual and population behaviors. We demonstrate: (i) population structuring
by independent closed-loop control of gene expression in many individual cells,
(ii) cell-cell variation control during antibiotic perturbation, (iii) hybrid
bio-digital circuits in single cells, and freely specifiable digital communication
between individual bacteria. These examples showcase the potential for real-time
integration of theoretical models with measurement and control of many individual
cells to investigate and engineer microbial population behavior.'
acknowledgement: We are grateful to M. Lang, H. Janovjak, M. Khammash, A. Milias-Argeitis,
M. Rullan, G. Batt, A. Bosma-Moody, Aryan, S. Leibler, and members of the Guet and
Tkačik groups for helpful discussion, comments, and suggestions. We thank A. Moglich,
T. Mathes, J. Tabor, and S. Schmidl for kind gifts of strains, and R. Hauschild,
B. Knep, M. Lang, T. Asenov, E. Papusheva, T. Menner, T. Adletzberger, and J. Merrin
for technical assistance. The research leading to these results has received funding
from the People Programme (Marie Curie Actions) of the European Union’s Seventh
Framework Programme (FP7/2007–2013) under REA grant agreement no. [291734]. (to
R.C. and J.R.), Austrian Science Fund grant FWF P28844 (to G.T.), and internal IST
Austria Interdisciplinary Project Support. J.R. acknowledges support from the Agence
Nationale de la Recherche (ANR) under Grant Nos. ANR-16-CE33-0018 (MEMIP), ANR-16-CE12-0025
(COGEX) and ANR-10-BINF-06-01 (ICEBERG).
article_number: '1535'
article_processing_charge: Yes (in subscription journal)
author:
- first_name: Remy P
full_name: Chait, Remy P
id: 3464AE84-F248-11E8-B48F-1D18A9856A87
last_name: Chait
orcid: 0000-0003-0876-3187
- first_name: Jakob
full_name: Ruess, Jakob
id: 4A245D00-F248-11E8-B48F-1D18A9856A87
last_name: Ruess
orcid: 0000-0003-1615-3282
- first_name: Tobias
full_name: Bergmiller, Tobias
id: 2C471CFA-F248-11E8-B48F-1D18A9856A87
last_name: Bergmiller
orcid: 0000-0001-5396-4346
- first_name: Gasper
full_name: Tkacik, Gasper
id: 3D494DCA-F248-11E8-B48F-1D18A9856A87
last_name: Tkacik
orcid: 0000-0002-6699-1455
- first_name: Calin C
full_name: Guet, Calin C
id: 47F8433E-F248-11E8-B48F-1D18A9856A87
last_name: Guet
orcid: 0000-0001-6220-2052
citation:
ama: Chait RP, Ruess J, Bergmiller T, Tkačik G, Guet CC. Shaping bacterial population
behavior through computer interfaced control of individual cells. Nature Communications.
2017;8(1). doi:10.1038/s41467-017-01683-1
apa: Chait, R. P., Ruess, J., Bergmiller, T., Tkačik, G., & Guet, C. C. (2017).
Shaping bacterial population behavior through computer interfaced control of individual
cells. Nature Communications. Nature Publishing Group. https://doi.org/10.1038/s41467-017-01683-1
chicago: Chait, Remy P, Jakob Ruess, Tobias Bergmiller, Gašper Tkačik, and Calin
C Guet. “Shaping Bacterial Population Behavior through Computer Interfaced Control
of Individual Cells.” Nature Communications. Nature Publishing Group, 2017.
https://doi.org/10.1038/s41467-017-01683-1.
ieee: R. P. Chait, J. Ruess, T. Bergmiller, G. Tkačik, and C. C. Guet, “Shaping
bacterial population behavior through computer interfaced control of individual
cells,” Nature Communications, vol. 8, no. 1. Nature Publishing Group,
2017.
ista: Chait RP, Ruess J, Bergmiller T, Tkačik G, Guet CC. 2017. Shaping bacterial
population behavior through computer interfaced control of individual cells. Nature
Communications. 8(1), 1535.
mla: Chait, Remy P., et al. “Shaping Bacterial Population Behavior through Computer
Interfaced Control of Individual Cells.” Nature Communications, vol. 8,
no. 1, 1535, Nature Publishing Group, 2017, doi:10.1038/s41467-017-01683-1.
short: R.P. Chait, J. Ruess, T. Bergmiller, G. Tkačik, C.C. Guet, Nature Communications
8 (2017).
date_created: 2018-12-11T11:47:30Z
date_published: 2017-12-01T00:00:00Z
date_updated: 2021-01-12T08:06:15Z
day: '01'
ddc:
- '576'
- '579'
department:
- _id: CaGu
- _id: GaTk
doi: 10.1038/s41467-017-01683-1
ec_funded: 1
file:
- access_level: open_access
checksum: 44bb5d0229926c23a9955d9fe0f9723f
content_type: application/pdf
creator: system
date_created: 2018-12-12T10:16:05Z
date_updated: 2020-07-14T12:47:20Z
file_id: '5190'
file_name: IST-2017-911-v1+1_s41467-017-01683-1.pdf
file_size: 1951699
relation: main_file
file_date_updated: 2020-07-14T12:47:20Z
has_accepted_license: '1'
intvolume: ' 8'
issue: '1'
language:
- iso: eng
month: '12'
oa: 1
oa_version: Published Version
project:
- _id: 25681D80-B435-11E9-9278-68D0E5697425
call_identifier: FP7
grant_number: '291734'
name: International IST Postdoc Fellowship Programme
- _id: 254E9036-B435-11E9-9278-68D0E5697425
call_identifier: FWF
grant_number: P28844-B27
name: Biophysics of information processing in gene regulation
publication: Nature Communications
publication_identifier:
issn:
- '20411723'
publication_status: published
publisher: Nature Publishing Group
publist_id: '7191'
pubrep_id: '911'
quality_controlled: '1'
scopus_import: 1
status: public
title: Shaping bacterial population behavior through computer interfaced control of
individual cells
tmp:
image: /images/cc_by.png
legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
short: CC BY (4.0)
type: journal_article
user_id: 3E5EF7F0-F248-11E8-B48F-1D18A9856A87
volume: 8
year: '2017'
...
---
_id: '615'
abstract:
- lang: eng
text: We show that the Dyson Brownian Motion exhibits local universality after a
very short time assuming that local rigidity and level repulsion of the eigenvalues
hold. These conditions are verified, hence bulk spectral universality is proven,
for a large class of Wigner-like matrices, including deformed Wigner ensembles
and ensembles with non-stochastic variance matrices whose limiting densities differ
from Wigner's semicircle law.
author:
- first_name: László
full_name: Erdös, László
id: 4DBD5372-F248-11E8-B48F-1D18A9856A87
last_name: Erdös
orcid: 0000-0001-5366-9603
- first_name: Kevin
full_name: Schnelli, Kevin
id: 434AD0AE-F248-11E8-B48F-1D18A9856A87
last_name: Schnelli
orcid: 0000-0003-0954-3231
citation:
ama: Erdös L, Schnelli K. Universality for random matrix flows with time dependent
density. Annales de l’institut Henri Poincare (B) Probability and Statistics.
2017;53(4):1606-1656. doi:10.1214/16-AIHP765
apa: Erdös, L., & Schnelli, K. (2017). Universality for random matrix flows
with time dependent density. Annales de l’institut Henri Poincare (B) Probability
and Statistics. Institute of Mathematical Statistics. https://doi.org/10.1214/16-AIHP765
chicago: Erdös, László, and Kevin Schnelli. “Universality for Random Matrix Flows
with Time Dependent Density.” Annales de l’institut Henri Poincare (B) Probability
and Statistics. Institute of Mathematical Statistics, 2017. https://doi.org/10.1214/16-AIHP765.
ieee: L. Erdös and K. Schnelli, “Universality for random matrix flows with time
dependent density,” Annales de l’institut Henri Poincare (B) Probability and
Statistics, vol. 53, no. 4. Institute of Mathematical Statistics, pp. 1606–1656,
2017.
ista: Erdös L, Schnelli K. 2017. Universality for random matrix flows with time
dependent density. Annales de l’institut Henri Poincare (B) Probability and Statistics.
53(4), 1606–1656.
mla: Erdös, László, and Kevin Schnelli. “Universality for Random Matrix Flows with
Time Dependent Density.” Annales de l’institut Henri Poincare (B) Probability
and Statistics, vol. 53, no. 4, Institute of Mathematical Statistics, 2017,
pp. 1606–56, doi:10.1214/16-AIHP765.
short: L. Erdös, K. Schnelli, Annales de l’institut Henri Poincare (B) Probability
and Statistics 53 (2017) 1606–1656.
date_created: 2018-12-11T11:47:30Z
date_published: 2017-11-01T00:00:00Z
date_updated: 2021-01-12T08:06:22Z
day: '01'
department:
- _id: LaEr
doi: 10.1214/16-AIHP765
ec_funded: 1
intvolume: ' 53'
issue: '4'
language:
- iso: eng
main_file_link:
- open_access: '1'
url: https://arxiv.org/abs/1504.00650
month: '11'
oa: 1
oa_version: Submitted Version
page: 1606 - 1656
project:
- _id: 258DCDE6-B435-11E9-9278-68D0E5697425
call_identifier: FP7
grant_number: '338804'
name: Random matrices, universality and disordered quantum systems
publication: Annales de l'institut Henri Poincare (B) Probability and Statistics
publication_identifier:
issn:
- '02460203'
publication_status: published
publisher: Institute of Mathematical Statistics
publist_id: '7189'
quality_controlled: '1'
scopus_import: 1
status: public
title: Universality for random matrix flows with time dependent density
type: journal_article
user_id: 4435EBFC-F248-11E8-B48F-1D18A9856A87
volume: 53
year: '2017'
...
---
_id: '618'
abstract:
- lang: eng
text: 'Background: Increasing temperatures are predicted to strongly impact host-parasite
interactions, but empirical tests are rare. Host species that are naturally exposed
to a broad temperature spectrum offer the possibility to investigate the effects
of elevated temperatures on hosts and parasites. Using three-spined sticklebacks,
Gasterosteus aculeatus L., and tapeworms, Schistocephalus solidus (Müller, 1776),
originating from a cold and a warm water site of a volcanic lake, we subjected
sympatric and allopatric host-parasite combinations to cold and warm conditions
in a fully crossed design. We predicted that warm temperatures would promote the
development of the parasites, while the hosts might benefit from cooler temperatures.
We further expected adaptations to the local temperature and mutual adaptations
of local host-parasite pairs. Results: Overall, S. solidus parasites grew faster
at warm temperatures and stickleback hosts at cold temperatures. On a finer scale,
we observed that parasites were able to exploit their hosts more efficiently at
the parasite’s temperature of origin. In contrast, host tolerance towards parasite
infection was higher when sticklebacks were infected with parasites at the parasite’s
‘foreign’ temperature. Cold-origin sticklebacks tended to grow faster and parasite
infection induced a stronger immune response. Conclusions: Our results suggest
that increasing environmental temperatures promote the parasite rather than the
host and that host tolerance is dependent on the interaction between parasite
infection and temperature. Sticklebacks might use tolerance mechanisms towards
parasite infection in combination with their high plasticity towards temperature
changes to cope with increasing parasite infection pressures and rising temperatures.'
article_number: '52'
author:
- first_name: Frederik
full_name: Franke, Frederik
last_name: Franke
- first_name: Sophie
full_name: Armitage, Sophie
last_name: Armitage
- first_name: Megan
full_name: Kutzer, Megan
id: 29D0B332-F248-11E8-B48F-1D18A9856A87
last_name: Kutzer
orcid: 0000-0002-8696-6978
- first_name: Joachim
full_name: Kurtz, Joachim
last_name: Kurtz
- first_name: Jörn
full_name: Scharsack, Jörn
last_name: Scharsack
citation:
ama: Franke F, Armitage S, Kutzer M, Kurtz J, Scharsack J. Environmental temperature
variation influences fitness trade-offs in a fish-tapeworm association . Parasites
& Vectors. 2017;10(252). doi:10.1186/s13071-017-2192-7
apa: Franke, F., Armitage, S., Kutzer, M., Kurtz, J., & Scharsack, J. (2017).
Environmental temperature variation influences fitness trade-offs in a fish-tapeworm
association . Parasites & Vectors. BioMed Central. https://doi.org/10.1186/s13071-017-2192-7
chicago: Franke, Frederik, Sophie Armitage, Megan Kutzer, Joachim Kurtz, and Jörn
Scharsack. “Environmental Temperature Variation Influences Fitness Trade-Offs
in a Fish-Tapeworm Association .” Parasites & Vectors. BioMed Central,
2017. https://doi.org/10.1186/s13071-017-2192-7.
ieee: F. Franke, S. Armitage, M. Kutzer, J. Kurtz, and J. Scharsack, “Environmental
temperature variation influences fitness trade-offs in a fish-tapeworm association
,” Parasites & Vectors, vol. 10, no. 252. BioMed Central, 2017.
ista: Franke F, Armitage S, Kutzer M, Kurtz J, Scharsack J. 2017. Environmental
temperature variation influences fitness trade-offs in a fish-tapeworm association
. Parasites & Vectors. 10(252), 52.
mla: Franke, Frederik, et al. “Environmental Temperature Variation Influences Fitness
Trade-Offs in a Fish-Tapeworm Association .” Parasites & Vectors, vol.
10, no. 252, 52, BioMed Central, 2017, doi:10.1186/s13071-017-2192-7.
short: F. Franke, S. Armitage, M. Kutzer, J. Kurtz, J. Scharsack, Parasites &
Vectors 10 (2017).
date_created: 2018-12-11T11:47:31Z
date_published: 2017-06-02T00:00:00Z
date_updated: 2021-01-12T08:06:35Z
day: '02'
ddc:
- '570'
doi: 10.1186/s13071-017-2192-7
extern: '1'
file:
- access_level: open_access
checksum: 742943377a38ee208108705b8e2f4dbf
content_type: application/pdf
creator: dernst
date_created: 2019-01-21T13:45:36Z
date_updated: 2020-07-14T12:47:22Z
file_id: '5864'
file_name: 2017_Parasites_Franke.pdf
file_size: 671807
relation: main_file
file_date_updated: 2020-07-14T12:47:22Z
has_accepted_license: '1'
intvolume: ' 10'
issue: '252'
language:
- iso: eng
month: '06'
oa: 1
oa_version: Published Version
publication: Parasites & Vectors
publication_identifier:
issn:
- '17563305'
publication_status: published
publisher: BioMed Central
publist_id: '7186'
quality_controlled: '1'
status: public
title: 'Environmental temperature variation influences fitness trade-offs in a fish-tapeworm
association '
tmp:
image: /images/cc_by.png
legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
short: CC BY (4.0)
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 10
year: '2017'
...
---
_id: '623'
abstract:
- lang: eng
text: Genetic factors might be largely responsible for the development of autism
spectrum disorder (ASD) that alone or in combination with specific environmental
risk factors trigger the pathology. Multiple mutations identified in ASD patients
that impair synaptic function in the central nervous system are well studied in
animal models. How these mutations might interact with other risk factors is not
fully understood though. Additionally, how systems outside of the brain are altered
in the context of ASD is an emerging area of research. Extracerebral influences
on the physiology could begin in utero and contribute to changes in the brain
and in the development of other body systems and further lead to epigenetic changes.
Therefore, multiple recent studies have aimed at elucidating the role of gene-environment
interactions in ASD. Here we provide an overview on the extracerebral systems
that might play an important associative role in ASD and review evidence regarding
the potential roles of inflammation, trace metals, metabolism, genetic susceptibility,
enteric nervous system function and the microbiota of the gastrointestinal (GI)
tract on the development of endophenotypes in animal models of ASD. By influencing
environmental conditions, it might be possible to reduce or limit the severity
of ASD pathology.
alternative_title:
- ADVSANAT
author:
- first_name: Elisa
full_name: Hill Yardin, Elisa
last_name: Hill Yardin
- first_name: Sonja
full_name: Mckeown, Sonja
last_name: Mckeown
- first_name: Gaia
full_name: Novarino, Gaia
id: 3E57A680-F248-11E8-B48F-1D18A9856A87
last_name: Novarino
orcid: 0000-0002-7673-7178
- first_name: Andreas
full_name: Grabrucker, Andreas
last_name: Grabrucker
citation:
ama: 'Hill Yardin E, Mckeown S, Novarino G, Grabrucker A. Extracerebral dysfunction
in animal models of autism spectrum disorder. In: Schmeisser M, Boekers T, eds.
Translational Anatomy and Cell Biology of Autism Spectrum Disorder. Vol
224. Advances in Anatomy Embryology and Cell Biology. Springer; 2017:159-187.
doi:10.1007/978-3-319-52498-6_9'
apa: Hill Yardin, E., Mckeown, S., Novarino, G., & Grabrucker, A. (2017). Extracerebral
dysfunction in animal models of autism spectrum disorder. In M. Schmeisser &
T. Boekers (Eds.), Translational Anatomy and Cell Biology of Autism Spectrum
Disorder (Vol. 224, pp. 159–187). Springer. https://doi.org/10.1007/978-3-319-52498-6_9
chicago: Hill Yardin, Elisa, Sonja Mckeown, Gaia Novarino, and Andreas Grabrucker.
“Extracerebral Dysfunction in Animal Models of Autism Spectrum Disorder.” In Translational
Anatomy and Cell Biology of Autism Spectrum Disorder, edited by Michael Schmeisser
and Tobias Boekers, 224:159–87. Advances in Anatomy Embryology and Cell Biology.
Springer, 2017. https://doi.org/10.1007/978-3-319-52498-6_9.
ieee: E. Hill Yardin, S. Mckeown, G. Novarino, and A. Grabrucker, “Extracerebral
dysfunction in animal models of autism spectrum disorder,” in Translational
Anatomy and Cell Biology of Autism Spectrum Disorder, vol. 224, M. Schmeisser
and T. Boekers, Eds. Springer, 2017, pp. 159–187.
ista: 'Hill Yardin E, Mckeown S, Novarino G, Grabrucker A. 2017.Extracerebral dysfunction
in animal models of autism spectrum disorder. In: Translational Anatomy and Cell
Biology of Autism Spectrum Disorder. ADVSANAT, vol. 224, 159–187.'
mla: Hill Yardin, Elisa, et al. “Extracerebral Dysfunction in Animal Models of Autism
Spectrum Disorder.” Translational Anatomy and Cell Biology of Autism Spectrum
Disorder, edited by Michael Schmeisser and Tobias Boekers, vol. 224, Springer,
2017, pp. 159–87, doi:10.1007/978-3-319-52498-6_9.
short: E. Hill Yardin, S. Mckeown, G. Novarino, A. Grabrucker, in:, M. Schmeisser,
T. Boekers (Eds.), Translational Anatomy and Cell Biology of Autism Spectrum Disorder,
Springer, 2017, pp. 159–187.
date_created: 2018-12-11T11:47:33Z
date_published: 2017-05-28T00:00:00Z
date_updated: 2021-01-12T08:06:46Z
day: '28'
department:
- _id: GaNo
doi: 10.1007/978-3-319-52498-6_9
editor:
- first_name: Michael
full_name: Schmeisser, Michael
last_name: Schmeisser
- first_name: Tobias
full_name: Boekers, Tobias
last_name: Boekers
intvolume: ' 224'
language:
- iso: eng
month: '05'
oa_version: None
page: 159 - 187
publication: Translational Anatomy and Cell Biology of Autism Spectrum Disorder
publication_identifier:
isbn:
- 978-3-319-52496-2
issn:
- '03015556'
publication_status: published
publisher: Springer
publist_id: '7177'
quality_controlled: '1'
scopus_import: 1
series_title: Advances in Anatomy Embryology and Cell Biology
status: public
title: Extracerebral dysfunction in animal models of autism spectrum disorder
type: book_chapter
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 224
year: '2017'
...
---
_id: '626'
abstract:
- lang: eng
text: 'Our focus here is on the infinitesimal model. In this model, one or several
quantitative traits are described as the sum of a genetic and a non-genetic component,
the first being distributed within families as a normal random variable centred
at the average of the parental genetic components, and with a variance independent
of the parental traits. Thus, the variance that segregates within families is
not perturbed by selection, and can be predicted from the variance components.
This does not necessarily imply that the trait distribution across the whole population
should be Gaussian, and indeed selection or population structure may have a substantial
effect on the overall trait distribution. One of our main aims is to identify
some general conditions on the allelic effects for the infinitesimal model to
be accurate. We first review the long history of the infinitesimal model in quantitative
genetics. Then we formulate the model at the phenotypic level in terms of individual
trait values and relationships between individuals, but including different evolutionary
processes: genetic drift, recombination, selection, mutation, population structure,
…. We give a range of examples of its application to evolutionary questions related
to stabilising selection, assortative mating, effective population size and response
to selection, habitat preference and speciation. We provide a mathematical justification
of the model as the limit as the number M of underlying loci tends to infinity
of a model with Mendelian inheritance, mutation and environmental noise, when
the genetic component of the trait is purely additive. We also show how the model
generalises to include epistatic effects. We prove in particular that, within
each family, the genetic components of the individual trait values in the current
generation are indeed normally distributed with a variance independent of ancestral
traits, up to an error of order 1∕M. Simulations suggest that in some cases the
convergence may be as fast as 1∕M.'
author:
- first_name: Nicholas H
full_name: Barton, Nicholas H
id: 4880FE40-F248-11E8-B48F-1D18A9856A87
last_name: Barton
orcid: 0000-0002-8548-5240
- first_name: Alison
full_name: Etheridge, Alison
last_name: Etheridge
- first_name: Amandine
full_name: Véber, Amandine
last_name: Véber
citation:
ama: 'Barton NH, Etheridge A, Véber A. The infinitesimal model: Definition derivation
and implications. Theoretical Population Biology. 2017;118:50-73. doi:10.1016/j.tpb.2017.06.001'
apa: 'Barton, N. H., Etheridge, A., & Véber, A. (2017). The infinitesimal model:
Definition derivation and implications. Theoretical Population Biology.
Academic Press. https://doi.org/10.1016/j.tpb.2017.06.001'
chicago: 'Barton, Nicholas H, Alison Etheridge, and Amandine Véber. “The Infinitesimal
Model: Definition Derivation and Implications.” Theoretical Population Biology.
Academic Press, 2017. https://doi.org/10.1016/j.tpb.2017.06.001.'
ieee: 'N. H. Barton, A. Etheridge, and A. Véber, “The infinitesimal model: Definition
derivation and implications,” Theoretical Population Biology, vol. 118.
Academic Press, pp. 50–73, 2017.'
ista: 'Barton NH, Etheridge A, Véber A. 2017. The infinitesimal model: Definition
derivation and implications. Theoretical Population Biology. 118, 50–73.'
mla: 'Barton, Nicholas H., et al. “The Infinitesimal Model: Definition Derivation
and Implications.” Theoretical Population Biology, vol. 118, Academic Press,
2017, pp. 50–73, doi:10.1016/j.tpb.2017.06.001.'
short: N.H. Barton, A. Etheridge, A. Véber, Theoretical Population Biology 118 (2017)
50–73.
date_created: 2018-12-11T11:47:34Z
date_published: 2017-12-01T00:00:00Z
date_updated: 2021-01-12T08:06:50Z
day: '01'
ddc:
- '576'
department:
- _id: NiBa
doi: 10.1016/j.tpb.2017.06.001
ec_funded: 1
file:
- access_level: open_access
checksum: 7dd02bfcfe8f244f4a6c19091aedf2c8
content_type: application/pdf
creator: system
date_created: 2018-12-12T10:12:45Z
date_updated: 2020-07-14T12:47:25Z
file_id: '4964'
file_name: IST-2017-908-v1+1_1-s2.0-S0040580917300886-main_1_.pdf
file_size: 1133924
relation: main_file
file_date_updated: 2020-07-14T12:47:25Z
has_accepted_license: '1'
intvolume: ' 118'
language:
- iso: eng
month: '12'
oa: 1
oa_version: Published Version
page: 50 - 73
project:
- _id: 25B07788-B435-11E9-9278-68D0E5697425
call_identifier: FP7
grant_number: '250152'
name: Limits to selection in biology and in evolutionary computation
publication: Theoretical Population Biology
publication_identifier:
issn:
- '00405809'
publication_status: published
publisher: Academic Press
publist_id: '7169'
pubrep_id: '908'
quality_controlled: '1'
scopus_import: 1
status: public
title: 'The infinitesimal model: Definition derivation and implications'
tmp:
image: /images/cc_by.png
legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
short: CC BY (4.0)
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 118
year: '2017'
...
---
_id: '625'
abstract:
- lang: eng
text: In the analysis of reactive systems a quantitative objective assigns a real
value to every trace of the system. The value decision problem for a quantitative
objective requires a trace whose value is at least a given threshold, and the
exact value decision problem requires a trace whose value is exactly the threshold.
We compare the computational complexity of the value and exact value decision
problems for classical quantitative objectives, such as sum, discounted sum, energy,
and mean-payoff for two standard models of reactive systems, namely, graphs and
graph games.
acknowledgement: 'This research was supported in part by the Austrian Science Fund
(FWF) under grants S11402-N23 and S11407-N23 (RiSE/SHiNE), and Z211-N23 (Wittgenstein
Award), ERC Start grant (279307: Graph Games), Vienna Science and Technology Fund
(WWTF) through project ICT15-003.'
alternative_title:
- LNCS
article_processing_charge: No
author:
- first_name: Krishnendu
full_name: Chatterjee, Krishnendu
id: 2E5DCA20-F248-11E8-B48F-1D18A9856A87
last_name: Chatterjee
orcid: 0000-0002-4561-241X
- first_name: Laurent
full_name: Doyen, Laurent
last_name: Doyen
- first_name: Thomas A
full_name: Henzinger, Thomas A
id: 40876CD8-F248-11E8-B48F-1D18A9856A87
last_name: Henzinger
orcid: 0000−0002−2985−7724
citation:
ama: 'Chatterjee K, Doyen L, Henzinger TA. The cost of exactness in quantitative
reachability. In: Aceto L, Bacci G, Ingólfsdóttir A, Legay A, Mardare R, eds.
Models, Algorithms, Logics and Tools. Vol 10460. Theoretical Computer Science
and General Issues. Springer; 2017:367-381. doi:10.1007/978-3-319-63121-9_18'
apa: Chatterjee, K., Doyen, L., & Henzinger, T. A. (2017). The cost of exactness
in quantitative reachability. In L. Aceto, G. Bacci, A. Ingólfsdóttir, A. Legay,
& R. Mardare (Eds.), Models, Algorithms, Logics and Tools (Vol. 10460,
pp. 367–381). Springer. https://doi.org/10.1007/978-3-319-63121-9_18
chicago: Chatterjee, Krishnendu, Laurent Doyen, and Thomas A Henzinger. “The Cost
of Exactness in Quantitative Reachability.” In Models, Algorithms, Logics and
Tools, edited by Luca Aceto, Giorgio Bacci, Anna Ingólfsdóttir, Axel Legay,
and Radu Mardare, 10460:367–81. Theoretical Computer Science and General Issues.
Springer, 2017. https://doi.org/10.1007/978-3-319-63121-9_18.
ieee: K. Chatterjee, L. Doyen, and T. A. Henzinger, “The cost of exactness in quantitative
reachability,” in Models, Algorithms, Logics and Tools, vol. 10460, L.
Aceto, G. Bacci, A. Ingólfsdóttir, A. Legay, and R. Mardare, Eds. Springer, 2017,
pp. 367–381.
ista: 'Chatterjee K, Doyen L, Henzinger TA. 2017.The cost of exactness in quantitative
reachability. In: Models, Algorithms, Logics and Tools. LNCS, vol. 10460, 367–381.'
mla: Chatterjee, Krishnendu, et al. “The Cost of Exactness in Quantitative Reachability.”
Models, Algorithms, Logics and Tools, edited by Luca Aceto et al., vol.
10460, Springer, 2017, pp. 367–81, doi:10.1007/978-3-319-63121-9_18.
short: K. Chatterjee, L. Doyen, T.A. Henzinger, in:, L. Aceto, G. Bacci, A. Ingólfsdóttir,
A. Legay, R. Mardare (Eds.), Models, Algorithms, Logics and Tools, Springer, 2017,
pp. 367–381.
date_created: 2018-12-11T11:47:34Z
date_published: 2017-07-25T00:00:00Z
date_updated: 2022-05-23T08:54:02Z
day: '25'
ddc:
- '000'
department:
- _id: KrCh
- _id: ToHe
doi: 10.1007/978-3-319-63121-9_18
ec_funded: 1
editor:
- first_name: Luca
full_name: Aceto, Luca
last_name: Aceto
- first_name: Giorgio
full_name: Bacci, Giorgio
last_name: Bacci
- first_name: Anna
full_name: Ingólfsdóttir, Anna
last_name: Ingólfsdóttir
- first_name: Axel
full_name: Legay, Axel
last_name: Legay
- first_name: Radu
full_name: Mardare, Radu
last_name: Mardare
file:
- access_level: open_access
checksum: b2402766ec02c79801aac634bd8f9f6c
content_type: application/pdf
creator: dernst
date_created: 2019-11-19T08:06:50Z
date_updated: 2020-07-14T12:47:25Z
file_id: '7048'
file_name: 2017_ModelsAlgorithms_Chatterjee.pdf
file_size: 192826
relation: main_file
file_date_updated: 2020-07-14T12:47:25Z
has_accepted_license: '1'
intvolume: ' 10460'
language:
- iso: eng
month: '07'
oa: 1
oa_version: Submitted Version
page: 367 - 381
project:
- _id: 25F5A88A-B435-11E9-9278-68D0E5697425
call_identifier: FWF
grant_number: S11402-N23
name: Moderne Concurrency Paradigms
- _id: 25863FF4-B435-11E9-9278-68D0E5697425
call_identifier: FWF
grant_number: S11407
name: Game Theory
- _id: 25F42A32-B435-11E9-9278-68D0E5697425
call_identifier: FWF
grant_number: Z211
name: The Wittgenstein Prize
- _id: 2581B60A-B435-11E9-9278-68D0E5697425
call_identifier: FP7
grant_number: '279307'
name: 'Quantitative Graph Games: Theory and Applications'
- _id: 25892FC0-B435-11E9-9278-68D0E5697425
grant_number: ICT15-003
name: Efficient Algorithms for Computer Aided Verification
publication: Models, Algorithms, Logics and Tools
publication_identifier:
isbn:
- 978-3-319-63120-2
issn:
- 0302-9743
publication_status: published
publisher: Springer
publist_id: '7170'
quality_controlled: '1'
scopus_import: '1'
series_title: Theoretical Computer Science and General Issues
status: public
title: The cost of exactness in quantitative reachability
type: book_chapter
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 10460
year: '2017'
...
---
_id: '624'
abstract:
- lang: eng
text: Bacteria adapt to adverse environmental conditions by altering gene expression
patterns. Recently, a novel stress adaptation mechanism has been described that
allows Escherichia coli to alter gene expression at the post-transcriptional level.
The key player in this regulatory pathway is the endoribonuclease MazF, the toxin
component of the toxin-antitoxin module mazEF that is triggered by various stressful
conditions. In general, MazF degrades the majority of transcripts by cleaving
at ACA sites, which results in the retardation of bacterial growth. Furthermore,
MazF can process a small subset of mRNAs and render them leaderless by removing
their ribosome binding site. MazF concomitantly modifies ribosomes, making them
selective for the translation of leaderless mRNAs. In this study, we employed
fluorescent reporter-systems to investigate mazEF expression during stressful
conditions, and to infer consequences of the mRNA processing mediated by MazF
on gene expression at the single-cell level. Our results suggest that mazEF transcription
is maintained at low levels in single cells encountering adverse conditions, such
as antibiotic stress or amino acid starvation. Moreover, using the grcA mRNA as
a model for MazF-mediated mRNA processing, we found that MazF activation promotes
heterogeneity in the grcA reporter expression, resulting in a subpopulation of
cells with increased levels of GrcA reporter protein.
acknowledgement: 'Austrian Science Fund (FWF): M1697, P22249; Swiss National Science
Foundation (SNF): 145706; European Commission;FWF Special Research Program: RNA-REG
F43'
article_number: '3830'
author:
- first_name: Nela
full_name: Nikolic, Nela
id: 42D9CABC-F248-11E8-B48F-1D18A9856A87
last_name: Nikolic
orcid: 0000-0001-9068-6090
- first_name: Zrinka
full_name: Didara, Zrinka
last_name: Didara
- first_name: Isabella
full_name: Moll, Isabella
last_name: Moll
citation:
ama: Nikolic N, Didara Z, Moll I. MazF activation promotes translational heterogeneity
of the grcA mRNA in Escherichia coli populations. PeerJ. 2017;2017(9).
doi:10.7717/peerj.3830
apa: Nikolic, N., Didara, Z., & Moll, I. (2017). MazF activation promotes translational
heterogeneity of the grcA mRNA in Escherichia coli populations. PeerJ.
PeerJ. https://doi.org/10.7717/peerj.3830
chicago: Nikolic, Nela, Zrinka Didara, and Isabella Moll. “MazF Activation Promotes
Translational Heterogeneity of the GrcA MRNA in Escherichia Coli Populations.”
PeerJ. PeerJ, 2017. https://doi.org/10.7717/peerj.3830.
ieee: N. Nikolic, Z. Didara, and I. Moll, “MazF activation promotes translational
heterogeneity of the grcA mRNA in Escherichia coli populations,” PeerJ,
vol. 2017, no. 9. PeerJ, 2017.
ista: Nikolic N, Didara Z, Moll I. 2017. MazF activation promotes translational
heterogeneity of the grcA mRNA in Escherichia coli populations. PeerJ. 2017(9),
3830.
mla: Nikolic, Nela, et al. “MazF Activation Promotes Translational Heterogeneity
of the GrcA MRNA in Escherichia Coli Populations.” PeerJ, vol. 2017, no.
9, 3830, PeerJ, 2017, doi:10.7717/peerj.3830.
short: N. Nikolic, Z. Didara, I. Moll, PeerJ 2017 (2017).
date_created: 2018-12-11T11:47:33Z
date_published: 2017-09-21T00:00:00Z
date_updated: 2021-01-12T08:06:48Z
day: '21'
ddc:
- '579'
department:
- _id: CaGu
doi: 10.7717/peerj.3830
file:
- access_level: open_access
checksum: 3d79ae6b6eabc90b0eaaed82ff3493b0
content_type: application/pdf
creator: system
date_created: 2018-12-12T10:11:51Z
date_updated: 2020-07-14T12:47:24Z
file_id: '4908'
file_name: IST-2017-909-v1+1_peerj-3830.pdf
file_size: 682064
relation: main_file
file_date_updated: 2020-07-14T12:47:24Z
has_accepted_license: '1'
intvolume: ' 2017'
issue: '9'
language:
- iso: eng
month: '09'
oa: 1
oa_version: Published Version
publication: PeerJ
publication_identifier:
issn:
- '21678359'
publication_status: published
publisher: PeerJ
publist_id: '7172'
pubrep_id: '909'
quality_controlled: '1'
scopus_import: 1
status: public
title: MazF activation promotes translational heterogeneity of the grcA mRNA in Escherichia
coli populations
tmp:
image: /images/cc_by.png
legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
short: CC BY (4.0)
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 2017
year: '2017'
...