[{"language":[{"iso":"eng"}],"publication_status":"published","publication_identifier":{"issn":["0009-2665"],"eissn":["1520-6890"]},"issue":"18","volume":117,"oa_version":"None","pmid":1,"abstract":[{"lang":"eng","text":"Flow chemistry involves the use of channels or tubing to conduct a reaction in a continuous stream rather than in a flask. Flow equipment provides chemists with unique control over reaction parameters enhancing reactivity or in some cases enabling new reactions. This relatively young technology has received a remarkable amount of attention in the past decade with many reports on what can be done in flow. Until recently, however, the question, “Should we do this in flow?” has merely been an afterthought. This review introduces readers to the basic principles and fundamentals of flow chemistry and critically discusses recent flow chemistry accounts."}],"intvolume":" 117","month":"06","scopus_import":"1","extern":"1","date_updated":"2023-02-21T10:09:28Z","_id":"11961","status":"public","type":"journal_article","article_type":"original","publication":"Chemical Reviews","day":"01","year":"2017","date_created":"2022-08-24T11:07:46Z","doi":"10.1021/acs.chemrev.7b00183","date_published":"2017-06-01T00:00:00Z","page":"11796-11893","quality_controlled":"1","publisher":"American Chemical Society","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","citation":{"short":"M.B. Plutschack, B. Pieber, K. Gilmore, P.H. Seeberger, Chemical Reviews 117 (2017) 11796–11893.","ieee":"M. B. Plutschack, B. Pieber, K. Gilmore, and P. H. Seeberger, “The Hitchhiker’s Guide to flow chemistry,” Chemical Reviews, vol. 117, no. 18. American Chemical Society, pp. 11796–11893, 2017.","ama":"Plutschack MB, Pieber B, Gilmore K, Seeberger PH. The Hitchhiker’s Guide to flow chemistry. Chemical Reviews. 2017;117(18):11796-11893. doi:10.1021/acs.chemrev.7b00183","apa":"Plutschack, M. B., Pieber, B., Gilmore, K., & Seeberger, P. H. (2017). The Hitchhiker’s Guide to flow chemistry. Chemical Reviews. American Chemical Society. https://doi.org/10.1021/acs.chemrev.7b00183","mla":"Plutschack, Matthew B., et al. “The Hitchhiker’s Guide to Flow Chemistry.” Chemical Reviews, vol. 117, no. 18, American Chemical Society, 2017, pp. 11796–893, doi:10.1021/acs.chemrev.7b00183.","ista":"Plutschack MB, Pieber B, Gilmore K, Seeberger PH. 2017. The Hitchhiker’s Guide to flow chemistry. Chemical Reviews. 117(18), 11796–11893.","chicago":"Plutschack, Matthew B., Bartholomäus Pieber, Kerry Gilmore, and Peter H. Seeberger. “The Hitchhiker’s Guide to Flow Chemistry.” Chemical Reviews. American Chemical Society, 2017. https://doi.org/10.1021/acs.chemrev.7b00183."},"title":"The Hitchhiker’s Guide to flow chemistry","external_id":{"pmid":["28570059"]},"article_processing_charge":"No","author":[{"last_name":"Plutschack","full_name":"Plutschack, Matthew B.","first_name":"Matthew B."},{"id":"93e5e5b2-0da6-11ed-8a41-af589a024726","first_name":"Bartholomäus","orcid":"0000-0001-8689-388X","full_name":"Pieber, Bartholomäus","last_name":"Pieber"},{"last_name":"Gilmore","full_name":"Gilmore, Kerry","first_name":"Kerry"},{"first_name":"Peter H.","full_name":"Seeberger, Peter H.","last_name":"Seeberger"}]},{"day":"01","publication":"Journal of Flow Chemistry","year":"2017","doi":"10.1556/1846.2017.00016","date_published":"2017-09-01T00:00:00Z","date_created":"2022-08-25T10:47:51Z","page":"129-136","publisher":"AKJournals","quality_controlled":"1","oa":1,"user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","citation":{"chicago":"Pieber, Bartholomäus, Kerry Gilmore, and Peter H. Seeberger. “Integrated Flow Processing - Challenges in Continuous Multistep Synthesis.” Journal of Flow Chemistry. AKJournals, 2017. https://doi.org/10.1556/1846.2017.00016.","ista":"Pieber B, Gilmore K, Seeberger PH. 2017. Integrated flow processing - challenges in continuous multistep synthesis. Journal of Flow Chemistry. 7(3–4), 129–136.","mla":"Pieber, Bartholomäus, et al. “Integrated Flow Processing - Challenges in Continuous Multistep Synthesis.” Journal of Flow Chemistry, vol. 7, no. 3–4, AKJournals, 2017, pp. 129–36, doi:10.1556/1846.2017.00016.","short":"B. Pieber, K. Gilmore, P.H. Seeberger, Journal of Flow Chemistry 7 (2017) 129–136.","ieee":"B. Pieber, K. Gilmore, and P. H. Seeberger, “Integrated flow processing - challenges in continuous multistep synthesis,” Journal of Flow Chemistry, vol. 7, no. 3–4. AKJournals, pp. 129–136, 2017.","apa":"Pieber, B., Gilmore, K., & Seeberger, P. H. (2017). Integrated flow processing - challenges in continuous multistep synthesis. Journal of Flow Chemistry. AKJournals. https://doi.org/10.1556/1846.2017.00016","ama":"Pieber B, Gilmore K, Seeberger PH. Integrated flow processing - challenges in continuous multistep synthesis. Journal of Flow Chemistry. 2017;7(3-4):129-136. doi:10.1556/1846.2017.00016"},"title":"Integrated flow processing - challenges in continuous multistep synthesis","author":[{"first_name":"Bartholomäus","id":"93e5e5b2-0da6-11ed-8a41-af589a024726","full_name":"Pieber, Bartholomäus","orcid":"0000-0001-8689-388X","last_name":"Pieber"},{"full_name":"Gilmore, Kerry","last_name":"Gilmore","first_name":"Kerry"},{"first_name":"Peter H.","last_name":"Seeberger","full_name":"Seeberger, Peter H."}],"article_processing_charge":"No","language":[{"iso":"eng"}],"publication_identifier":{"eissn":["2063-0212"],"issn":["2062-249X"]},"publication_status":"published","issue":"3-4","volume":7,"oa_version":"Published Version","abstract":[{"text":"The way organic multistep synthesis is performed is changing due to the adoption of flow chemical techniques, which has enabled the development of improved methods to make complex molecules. The modular nature of the technique provides not only access to target molecules via linear flow approaches but also for the targeting of structural cores with single systems. This perspective article summarizes the state of the art of continuous multistep synthesis and discusses the main challenges and opportunities in this area.","lang":"eng"}],"month":"09","intvolume":" 7","scopus_import":"1","main_file_link":[{"url":"https://doi.org/10.1556/1846.2017.00016","open_access":"1"}],"extern":"1","date_updated":"2023-02-21T10:10:02Z","_id":"11976","status":"public","article_type":"original","type":"journal_article"},{"status":"public","pubrep_id":"782","type":"journal_article","_id":"1211","department":[{"_id":"BjHo"}],"file_date_updated":"2020-07-14T12:44:39Z","ddc":["530"],"date_updated":"2021-01-12T06:49:07Z","month":"05","intvolume":" 167","scopus_import":1,"oa_version":"Submitted Version","abstract":[{"text":"Systems such as fluid flows in channels and pipes or the complex Ginzburg–Landau system, defined over periodic domains, exhibit both continuous symmetries, translational and rotational, as well as discrete symmetries under spatial reflections or complex conjugation. The simplest, and very common symmetry of this type is the equivariance of the defining equations under the orthogonal group O(2). We formulate a novel symmetry reduction scheme for such systems by combining the method of slices with invariant polynomial methods, and show how it works by applying it to the Kuramoto–Sivashinsky system in one spatial dimension. As an example, we track a relative periodic orbit through a sequence of bifurcations to the onset of chaos. Within the symmetry-reduced state space we are able to compute and visualize the unstable manifolds of relative periodic orbits, their torus bifurcations, a transition to chaos via torus breakdown, and heteroclinic connections between various relative periodic orbits. It would be very hard to carry through such analysis in the full state space, without a symmetry reduction such as the one we present here.","lang":"eng"}],"volume":167,"issue":"3-4","file":[{"checksum":"3e971d09eb167761aa0888ed415b0056","file_id":"5319","relation":"main_file","access_level":"open_access","content_type":"application/pdf","file_name":"IST-2017-782-v1+1_BudCvi15.pdf","date_created":"2018-12-12T10:18:01Z","creator":"system","file_size":2820207,"date_updated":"2020-07-14T12:44:39Z"}],"language":[{"iso":"eng"}],"publication_status":"published","title":"Unstable manifolds of relative periodic orbits in the symmetry reduced state space of the Kuramoto–Sivashinsky system","publist_id":"6136","author":[{"last_name":"Budanur","orcid":"0000-0003-0423-5010","full_name":"Budanur, Nazmi B","first_name":"Nazmi B","id":"3EA1010E-F248-11E8-B48F-1D18A9856A87"},{"first_name":"Predrag","last_name":"Cvitanović","full_name":"Cvitanović, Predrag"}],"user_id":"3E5EF7F0-F248-11E8-B48F-1D18A9856A87","citation":{"ieee":"N. B. Budanur and P. Cvitanović, “Unstable manifolds of relative periodic orbits in the symmetry reduced state space of the Kuramoto–Sivashinsky system,” Journal of Statistical Physics, vol. 167, no. 3–4. Springer, pp. 636–655, 2017.","short":"N.B. Budanur, P. Cvitanović, Journal of Statistical Physics 167 (2017) 636–655.","ama":"Budanur NB, Cvitanović P. Unstable manifolds of relative periodic orbits in the symmetry reduced state space of the Kuramoto–Sivashinsky system. Journal of Statistical Physics. 2017;167(3-4):636-655. doi:10.1007/s10955-016-1672-z","apa":"Budanur, N. B., & Cvitanović, P. (2017). Unstable manifolds of relative periodic orbits in the symmetry reduced state space of the Kuramoto–Sivashinsky system. Journal of Statistical Physics. Springer. https://doi.org/10.1007/s10955-016-1672-z","mla":"Budanur, Nazmi B., and Predrag Cvitanović. “Unstable Manifolds of Relative Periodic Orbits in the Symmetry Reduced State Space of the Kuramoto–Sivashinsky System.” Journal of Statistical Physics, vol. 167, no. 3–4, Springer, 2017, pp. 636–55, doi:10.1007/s10955-016-1672-z.","ista":"Budanur NB, Cvitanović P. 2017. Unstable manifolds of relative periodic orbits in the symmetry reduced state space of the Kuramoto–Sivashinsky system. Journal of Statistical Physics. 167(3–4), 636–655.","chicago":"Budanur, Nazmi B, and Predrag Cvitanović. “Unstable Manifolds of Relative Periodic Orbits in the Symmetry Reduced State Space of the Kuramoto–Sivashinsky System.” Journal of Statistical Physics. Springer, 2017. https://doi.org/10.1007/s10955-016-1672-z."},"publisher":"Springer","quality_controlled":"1","oa":1,"acknowledgement":"This work was supported by the family of late G. Robinson, Jr. and NSF Grant DMS-1211827. ","date_published":"2017-05-01T00:00:00Z","doi":"10.1007/s10955-016-1672-z","date_created":"2018-12-11T11:50:44Z","page":"636-655","day":"01","publication":"Journal of Statistical Physics","has_accepted_license":"1","year":"2017"},{"acknowledgement":"A.S. acknowledges funding from the Delta Institute for Theoretical Physics and the hospitality of the IBS Center for Theoretical Physics of Complex Systems, Daejeon, South Korea. We acknowledge funding from the Netherlands Organisation for Scientific Research through grants VICI No. NWO-680-47-609 (M.v.H. and S.R.W.), VENI No. NWO-680-47-445 (C.C.) and VENI No. NWO-680-47-453 (S.R.W.).","quality_controlled":"1","publisher":"Nature Publishing Group","oa":1,"day":"24","publication":"Nature Physics","year":"2017","doi":"10.1038/nphys4194","date_published":"2017-07-24T00:00:00Z","date_created":"2018-12-11T11:44:45Z","page":"1095 - 1099","user_id":"3E5EF7F0-F248-11E8-B48F-1D18A9856A87","citation":{"chicago":"Waitukaitis, Scott R, Antal Zuiderwijk, Anton Souslov, Corentin Coulais, and Martin Van Hecke. “Coupling the Leidenfrost Effect and Elastic Deformations to Power Sustained Bouncing.” Nature Physics. Nature Publishing Group, 2017. https://doi.org/10.1038/nphys4194.","ista":"Waitukaitis SR, Zuiderwijk A, Souslov A, Coulais C, Van Hecke M. 2017. Coupling the Leidenfrost effect and elastic deformations to power sustained bouncing. Nature Physics. 13(11), 1095–1099.","mla":"Waitukaitis, Scott R., et al. “Coupling the Leidenfrost Effect and Elastic Deformations to Power Sustained Bouncing.” Nature Physics, vol. 13, no. 11, Nature Publishing Group, 2017, pp. 1095–99, doi:10.1038/nphys4194.","ama":"Waitukaitis SR, Zuiderwijk A, Souslov A, Coulais C, Van Hecke M. Coupling the Leidenfrost effect and elastic deformations to power sustained bouncing. Nature Physics. 2017;13(11):1095-1099. doi:10.1038/nphys4194","apa":"Waitukaitis, S. R., Zuiderwijk, A., Souslov, A., Coulais, C., & Van Hecke, M. (2017). Coupling the Leidenfrost effect and elastic deformations to power sustained bouncing. Nature Physics. Nature Publishing Group. https://doi.org/10.1038/nphys4194","ieee":"S. R. Waitukaitis, A. Zuiderwijk, A. Souslov, C. Coulais, and M. Van Hecke, “Coupling the Leidenfrost effect and elastic deformations to power sustained bouncing,” Nature Physics, vol. 13, no. 11. Nature Publishing Group, pp. 1095–1099, 2017.","short":"S.R. Waitukaitis, A. Zuiderwijk, A. Souslov, C. Coulais, M. Van Hecke, Nature Physics 13 (2017) 1095–1099."},"title":"Coupling the Leidenfrost effect and elastic deformations to power sustained bouncing","publist_id":"7931","author":[{"last_name":"Waitukaitis","full_name":"Waitukaitis, Scott R","orcid":"0000-0002-2299-3176","first_name":"Scott R","id":"3A1FFC16-F248-11E8-B48F-1D18A9856A87"},{"last_name":"Zuiderwijk","full_name":"Zuiderwijk, Antal","first_name":"Antal"},{"first_name":"Anton","full_name":"Souslov, Anton","last_name":"Souslov"},{"first_name":"Corentin","full_name":"Coulais, Corentin","last_name":"Coulais"},{"last_name":"Van Hecke","full_name":"Van Hecke, Martin","first_name":"Martin"}],"external_id":{"arxiv":["1705.03530"]},"oa_version":"Preprint","abstract":[{"lang":"eng","text":"The Leidenfrost effect occurs when an object near a hot surface vaporizes rapidly enough to lift itself up and hover. Although well understood for liquids and stiff sublimable solids, nothing is known about the effect with materials whose stiffness lies between these extremes. Here we introduce a new phenomenon that occurs with vaporizable soft solids - the elastic Leidenfrost effect. By dropping hydrogel spheres onto hot surfaces we find that, rather than hovering, they energetically bounce several times their diameter for minutes at a time. With high-speed video during a single impact, we uncover high-frequency microscopic gap dynamics at the sphere/substrate interface. We show how these otherwise-hidden agitations constitute work cycles that harvest mechanical energy from the vapour and sustain the bouncing. Our findings suggest a new strategy for injecting mechanical energy into a widely used class of soft materials, with potential relevance to fields such as active matter, soft robotics and microfluidics."}],"month":"07","intvolume":" 13","main_file_link":[{"url":"https://arxiv.org/abs/1705.03530","open_access":"1"}],"language":[{"iso":"eng"}],"publication_status":"published","issue":"11","volume":13,"_id":"123","status":"public","type":"journal_article","extern":"1","date_updated":"2021-01-12T06:49:14Z"},{"main_file_link":[{"url":"https://arxiv.org/abs/1611.00198","open_access":"1"}],"scopus_import":"1","alternative_title":["LNCS"],"intvolume":" 10328","month":"05","abstract":[{"lang":"eng","text":"We consider the problems of maintaining approximate maximum matching and minimum vertex cover in a dynamic graph. Starting with the seminal work of Onak and Rubinfeld [STOC 2010], this problem has received significant attention in recent years. Very recently, extending the framework of Baswana, Gupta and Sen [FOCS 2011], Solomon [FOCS 2016] gave a randomized 2-approximation dynamic algorithm for this problem that has amortized update time of O(1) with high probability. We consider the natural open question of derandomizing this result. We present a new deterministic fully dynamic algorithm that maintains a O(1)-approximate minimum vertex cover and maximum fractional matching, with an amortized update time of O(1). Previously, the best deterministic algorithm for this problem was due to Bhattacharya, Henzinger and Italiano [SODA 2015]; it had an approximation ratio of (2+ϵ) and an amortized update time of O(logn/ϵ2). Our result can be generalized to give a fully dynamic O(f3)-approximation algorithm with O(f2) amortized update time for the hypergraph vertex cover and fractional matching problems, where every hyperedge has at most f vertices."}],"oa_version":"Preprint","volume":10328,"publication_status":"published","publication_identifier":{"isbn":["9783319592497"],"issn":["0302-9743","1611-3349"],"eisbn":["9783319592503"]},"language":[{"iso":"eng"}],"conference":{"start_date":"2017-06-26","end_date":"2017-06-28","location":"Waterloo, ON, Canada","name":"IPCO: Integer Programming and Combinatorial Optimization"},"type":"conference","status":"public","_id":"12571","date_updated":"2023-02-20T07:57:24Z","extern":"1","oa":1,"publisher":"Springer Nature","quality_controlled":"1","page":"86-98","date_created":"2023-02-20T07:52:31Z","date_published":"2017-05-24T00:00:00Z","doi":"10.1007/978-3-319-59250-3_8","year":"2017","publication":"19th International Conference on Integer Programming and Combinatorial Optimization","day":"24","article_processing_charge":"No","external_id":{"arxiv":["1611.00198"]},"author":[{"first_name":"Sayan","full_name":"Bhattacharya, Sayan","last_name":"Bhattacharya"},{"first_name":"Deeparnab","last_name":"Chakrabarty","full_name":"Chakrabarty, Deeparnab"},{"last_name":"Henzinger","full_name":"Henzinger, Monika H","orcid":"0000-0002-5008-6530","first_name":"Monika H","id":"540c9bbd-f2de-11ec-812d-d04a5be85630"}],"title":"Deterministic fully dynamic approximate vertex cover and fractional matching in O(1) amortized update time","citation":{"ista":"Bhattacharya S, Chakrabarty D, Henzinger MH. 2017. Deterministic fully dynamic approximate vertex cover and fractional matching in O(1) amortized update time. 19th International Conference on Integer Programming and Combinatorial Optimization. IPCO: Integer Programming and Combinatorial Optimization, LNCS, vol. 10328, 86–98.","chicago":"Bhattacharya, Sayan, Deeparnab Chakrabarty, and Monika H Henzinger. “Deterministic Fully Dynamic Approximate Vertex Cover and Fractional Matching in O(1) Amortized Update Time.” In 19th International Conference on Integer Programming and Combinatorial Optimization, 10328:86–98. Springer Nature, 2017. https://doi.org/10.1007/978-3-319-59250-3_8.","ieee":"S. Bhattacharya, D. Chakrabarty, and M. H. Henzinger, “Deterministic fully dynamic approximate vertex cover and fractional matching in O(1) amortized update time,” in 19th International Conference on Integer Programming and Combinatorial Optimization, Waterloo, ON, Canada, 2017, vol. 10328, pp. 86–98.","short":"S. Bhattacharya, D. Chakrabarty, M.H. Henzinger, in:, 19th International Conference on Integer Programming and Combinatorial Optimization, Springer Nature, 2017, pp. 86–98.","apa":"Bhattacharya, S., Chakrabarty, D., & Henzinger, M. H. (2017). Deterministic fully dynamic approximate vertex cover and fractional matching in O(1) amortized update time. In 19th International Conference on Integer Programming and Combinatorial Optimization (Vol. 10328, pp. 86–98). Waterloo, ON, Canada: Springer Nature. https://doi.org/10.1007/978-3-319-59250-3_8","ama":"Bhattacharya S, Chakrabarty D, Henzinger MH. Deterministic fully dynamic approximate vertex cover and fractional matching in O(1) amortized update time. In: 19th International Conference on Integer Programming and Combinatorial Optimization. Vol 10328. Springer Nature; 2017:86-98. doi:10.1007/978-3-319-59250-3_8","mla":"Bhattacharya, Sayan, et al. “Deterministic Fully Dynamic Approximate Vertex Cover and Fractional Matching in O(1) Amortized Update Time.” 19th International Conference on Integer Programming and Combinatorial Optimization, vol. 10328, Springer Nature, 2017, pp. 86–98, doi:10.1007/978-3-319-59250-3_8."},"user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87"},{"ec_funded":1,"volume":21,"related_material":{"record":[{"relation":"earlier_version","id":"1164","status":"public"},{"relation":"earlier_version","id":"1595","status":"public"}]},"issue":"1","language":[{"iso":"eng"}],"file":[{"date_created":"2019-10-24T10:54:37Z","file_name":"2017_JournalGraphAlgorithms_Fulek.pdf","date_updated":"2019-10-24T10:54:37Z","file_size":573623,"creator":"dernst","file_id":"6967","success":1,"content_type":"application/pdf","access_level":"open_access","relation":"main_file"}],"publication_status":"published","intvolume":" 21","month":"01","scopus_import":1,"oa_version":"Published Version","abstract":[{"lang":"eng","text":"A drawing of a graph G is radial if the vertices of G are placed on concentric circles C 1 , . . . , C k with common center c , and edges are drawn radially : every edge intersects every circle centered at c at most once. G is radial planar if it has a radial embedding, that is, a crossing-free radial drawing. If the vertices of G are ordered or partitioned into ordered levels (as they are for leveled graphs), we require that the assignment of vertices to circles corresponds to the given ordering or leveling. We show that a graph G is radial planar if G has a radial drawing in which every two edges cross an even number of times; the radial embedding has the same leveling as the radial drawing. In other words, we establish the weak variant of the Hanani-Tutte theorem for radial planarity. This generalizes a result by Pach and Toth."}],"department":[{"_id":"UlWa"}],"file_date_updated":"2019-10-24T10:54:37Z","ddc":["510"],"date_updated":"2023-02-23T10:05:57Z","status":"public","type":"journal_article","article_type":"original","_id":"1113","date_created":"2018-12-11T11:50:13Z","date_published":"2017-01-01T00:00:00Z","doi":"10.7155/jgaa.00408","page":"135 - 154","publication":"Journal of Graph Algorithms and Applications","day":"01","year":"2017","has_accepted_license":"1","oa":1,"publisher":"Brown University","quality_controlled":"1","title":"Hanani-Tutte for radial planarity","external_id":{"arxiv":["1608.08662"]},"article_processing_charge":"No","author":[{"id":"39F3FFE4-F248-11E8-B48F-1D18A9856A87","first_name":"Radoslav","orcid":"0000-0001-8485-1774","full_name":"Fulek, Radoslav","last_name":"Fulek"},{"first_name":"Michael","full_name":"Pelsmajer, Michael","last_name":"Pelsmajer"},{"first_name":"Marcus","last_name":"Schaefer","full_name":"Schaefer, Marcus"}],"publist_id":"6254","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","citation":{"ista":"Fulek R, Pelsmajer M, Schaefer M. 2017. Hanani-Tutte for radial planarity. Journal of Graph Algorithms and Applications. 21(1), 135–154.","chicago":"Fulek, Radoslav, Michael Pelsmajer, and Marcus Schaefer. “Hanani-Tutte for Radial Planarity.” Journal of Graph Algorithms and Applications. Brown University, 2017. https://doi.org/10.7155/jgaa.00408.","ieee":"R. Fulek, M. Pelsmajer, and M. Schaefer, “Hanani-Tutte for radial planarity,” Journal of Graph Algorithms and Applications, vol. 21, no. 1. Brown University, pp. 135–154, 2017.","short":"R. Fulek, M. Pelsmajer, M. Schaefer, Journal of Graph Algorithms and Applications 21 (2017) 135–154.","ama":"Fulek R, Pelsmajer M, Schaefer M. Hanani-Tutte for radial planarity. Journal of Graph Algorithms and Applications. 2017;21(1):135-154. doi:10.7155/jgaa.00408","apa":"Fulek, R., Pelsmajer, M., & Schaefer, M. (2017). Hanani-Tutte for radial planarity. Journal of Graph Algorithms and Applications. Brown University. https://doi.org/10.7155/jgaa.00408","mla":"Fulek, Radoslav, et al. “Hanani-Tutte for Radial Planarity.” Journal of Graph Algorithms and Applications, vol. 21, no. 1, Brown University, 2017, pp. 135–54, doi:10.7155/jgaa.00408."},"project":[{"name":"International IST Postdoc Fellowship Programme","grant_number":"291734","call_identifier":"FP7","_id":"25681D80-B435-11E9-9278-68D0E5697425"}]},{"publist_id":"7752","author":[{"id":"35827D50-F248-11E8-B48F-1D18A9856A87","first_name":"Timothy D","orcid":"0000-0002-8314-0177","full_name":"Browning, Timothy D","last_name":"Browning"},{"full_name":"Kumaraswamy, Vinay","last_name":"Kumaraswamy","first_name":"Vinay"},{"first_name":"Rapael","full_name":"Steiner, Rapael","last_name":"Steiner"}],"article_processing_charge":"No","external_id":{"arxiv":["1609.06097"]},"title":"Twisted Linnik implies optimal covering exponent for S3","citation":{"chicago":"Browning, Timothy D, Vinay Kumaraswamy, and Rapael Steiner. “Twisted Linnik Implies Optimal Covering Exponent for S3.” International Mathematics Research Notices. Oxford University Press, 2017. https://doi.org/10.1093/imrn/rnx116.","ista":"Browning TD, Kumaraswamy V, Steiner R. 2017. Twisted Linnik implies optimal covering exponent for S3. International Mathematics Research Notices.","mla":"Browning, Timothy D., et al. “Twisted Linnik Implies Optimal Covering Exponent for S3.” International Mathematics Research Notices, Oxford University Press, 2017, doi:10.1093/imrn/rnx116.","apa":"Browning, T. D., Kumaraswamy, V., & Steiner, R. (2017). Twisted Linnik implies optimal covering exponent for S3. International Mathematics Research Notices. Oxford University Press. https://doi.org/10.1093/imrn/rnx116","ama":"Browning TD, Kumaraswamy V, Steiner R. Twisted Linnik implies optimal covering exponent for S3. International Mathematics Research Notices. 2017. doi:10.1093/imrn/rnx116","ieee":"T. D. Browning, V. Kumaraswamy, and R. Steiner, “Twisted Linnik implies optimal covering exponent for S3,” International Mathematics Research Notices. Oxford University Press, 2017.","short":"T.D. Browning, V. Kumaraswamy, R. Steiner, International Mathematics Research Notices (2017)."},"date_updated":"2021-01-12T06:52:32Z","extern":"1","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","type":"journal_article","status":"public","_id":"169","doi":"10.1093/imrn/rnx116","date_published":"2017-06-19T00:00:00Z","date_created":"2018-12-11T11:44:59Z","year":"2017","publication_status":"published","day":"19","language":[{"iso":"eng"}],"publication":"International Mathematics Research Notices","quality_controlled":"1","publisher":"Oxford University Press","oa":1,"main_file_link":[{"open_access":"1","url":"https://arxiv.org/abs/1609.06097"}],"month":"06","abstract":[{"text":"We show that a twisted variant of Linnik’s conjecture on sums of Kloosterman sums leads to an optimal covering exponent for S3.","lang":"eng"}],"oa_version":"None"},{"publication_status":"published","year":"2017","language":[{"iso":"eng"}],"publication":"International Mathematics Research Notices","day":"30","date_created":"2018-12-11T11:45:00Z","date_published":"2017-10-30T00:00:00Z","doi":"10.1093/imrn/rnx252","abstract":[{"lang":"eng","text":"We study strong approximation for some algebraic varieties over ℚ which are defined using norm forms. This allows us to confirm a special case of a conjecture due to Harpaz and Wittenberg."}],"oa_version":"None","main_file_link":[{"open_access":"1","url":"https://arxiv.org/abs/1509.07744"}],"oa":1,"publisher":"Oxford University Press","quality_controlled":"1","month":"10","date_updated":"2021-01-12T06:52:45Z","citation":{"short":"T.D. Browning, D. Schindler, International Mathematics Research Notices (2017).","ieee":"T. D. Browning and D. Schindler, “Strong approximation and a conjecture of Harpaz and Wittenberg,” International Mathematics Research Notices. Oxford University Press, 2017.","ama":"Browning TD, Schindler D. Strong approximation and a conjecture of Harpaz and Wittenberg. International Mathematics Research Notices. 2017. doi:10.1093/imrn/rnx252","apa":"Browning, T. D., & Schindler, D. (2017). Strong approximation and a conjecture of Harpaz and Wittenberg. International Mathematics Research Notices. Oxford University Press. https://doi.org/10.1093/imrn/rnx252","mla":"Browning, Timothy D., and Damaris Schindler. “Strong Approximation and a Conjecture of Harpaz and Wittenberg.” International Mathematics Research Notices, Oxford University Press, 2017, doi:10.1093/imrn/rnx252.","ista":"Browning TD, Schindler D. 2017. Strong approximation and a conjecture of Harpaz and Wittenberg. International Mathematics Research Notices.","chicago":"Browning, Timothy D, and Damaris Schindler. “Strong Approximation and a Conjecture of Harpaz and Wittenberg.” International Mathematics Research Notices. Oxford University Press, 2017. https://doi.org/10.1093/imrn/rnx252."},"user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","extern":"1","external_id":{"arxiv":["1509.07744"]},"article_processing_charge":"No","author":[{"id":"35827D50-F248-11E8-B48F-1D18A9856A87","first_name":"Timothy D","last_name":"Browning","orcid":"0000-0002-8314-0177","full_name":"Browning, Timothy D"},{"full_name":"Schindler, Damaris","last_name":"Schindler","first_name":"Damaris"}],"publist_id":"7749","title":"Strong approximation and a conjecture of Harpaz and Wittenberg","_id":"172","type":"journal_article","status":"public"},{"status":"public","type":"journal_article","_id":"391","title":"Disorder enabled band structure engineering of a topological insulator surface","author":[{"full_name":"Xu, Yishuai","last_name":"Xu","first_name":"Yishuai"},{"last_name":"Chiu","full_name":"Chiu, Janet","first_name":"Janet"},{"last_name":"Miao","full_name":"Miao, Lin","first_name":"Lin"},{"last_name":"He","full_name":"He, Haowei","first_name":"Haowei"},{"last_name":"Alpichshev","orcid":"0000-0002-7183-5203","full_name":"Alpichshev, Zhanybek","first_name":"Zhanybek","id":"45E67A2A-F248-11E8-B48F-1D18A9856A87"},{"last_name":"Kapitulnik","full_name":"Kapitulnik, Aharon","first_name":"Aharon"},{"full_name":"Biswas, Rudro","last_name":"Biswas","first_name":"Rudro"},{"full_name":"Wray, Lewis","last_name":"Wray","first_name":"Lewis"}],"publist_id":"7438","extern":"1","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","citation":{"ista":"Xu Y, Chiu J, Miao L, He H, Alpichshev Z, Kapitulnik A, Biswas R, Wray L. 2017. Disorder enabled band structure engineering of a topological insulator surface. Nature Communications. 8.","chicago":"Xu, Yishuai, Janet Chiu, Lin Miao, Haowei He, Zhanybek Alpichshev, Aharon Kapitulnik, Rudro Biswas, and Lewis Wray. “Disorder Enabled Band Structure Engineering of a Topological Insulator Surface.” Nature Communications. Nature Publishing Group, 2017. https://doi.org/10.1038/ncomms14081.","apa":"Xu, Y., Chiu, J., Miao, L., He, H., Alpichshev, Z., Kapitulnik, A., … Wray, L. (2017). Disorder enabled band structure engineering of a topological insulator surface. Nature Communications. Nature Publishing Group. https://doi.org/10.1038/ncomms14081","ama":"Xu Y, Chiu J, Miao L, et al. Disorder enabled band structure engineering of a topological insulator surface. Nature Communications. 2017;8. doi:10.1038/ncomms14081","ieee":"Y. Xu et al., “Disorder enabled band structure engineering of a topological insulator surface,” Nature Communications, vol. 8. Nature Publishing Group, 2017.","short":"Y. Xu, J. Chiu, L. Miao, H. He, Z. Alpichshev, A. Kapitulnik, R. Biswas, L. Wray, Nature Communications 8 (2017).","mla":"Xu, Yishuai, et al. “Disorder Enabled Band Structure Engineering of a Topological Insulator Surface.” Nature Communications, vol. 8, Nature Publishing Group, 2017, doi:10.1038/ncomms14081."},"date_updated":"2021-01-12T07:53:08Z","month":"02","intvolume":" 8","publisher":"Nature Publishing Group","oa_version":"None","abstract":[{"text":"Three-dimensional topological insulators are bulk insulators with Z 2 topological electronic order that gives rise to conducting light-like surface states. These surface electrons are exceptionally resistant to localization by non-magnetic disorder, and have been adopted as the basis for a wide range of proposals to achieve new quasiparticle species and device functionality. Recent studies have yielded a surprise by showing that in spite of resisting localization, topological insulator surface electrons can be reshaped by defects into distinctive resonance states. Here we use numerical simulations and scanning tunnelling microscopy data to show that these resonance states have significance well beyond the localized regime usually associated with impurity bands. At native densities in the model Bi2X3 (X=Bi, Te) compounds, defect resonance states are predicted to generate a new quantum basis for an emergent electron gas that supports diffusive electrical transport. ","lang":"eng"}],"volume":8,"date_published":"2017-02-03T00:00:00Z","doi":"10.1038/ncomms14081","date_created":"2018-12-11T11:46:12Z","day":"03","language":[{"iso":"eng"}],"publication":"Nature Communications","year":"2017","publication_status":"published"},{"extern":"1","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","date_updated":"2021-01-12T07:53:16Z","citation":{"ama":"Alpichshev Z, Sie E, Mahmood F, Cao G, Gedik N. Origin of the exciton mass in the frustrated Mott insulator Na2IrO3. Physical Review B. 2017;96(23). doi:10.1103/PhysRevB.96.235141","apa":"Alpichshev, Z., Sie, E., Mahmood, F., Cao, G., & Gedik, N. (2017). Origin of the exciton mass in the frustrated Mott insulator Na2IrO3. Physical Review B. American Physical Society. https://doi.org/10.1103/PhysRevB.96.235141","short":"Z. Alpichshev, E. Sie, F. Mahmood, G. Cao, N. Gedik, Physical Review B 96 (2017).","ieee":"Z. Alpichshev, E. Sie, F. Mahmood, G. Cao, and N. Gedik, “Origin of the exciton mass in the frustrated Mott insulator Na2IrO3,” Physical Review B, vol. 96, no. 23. American Physical Society, 2017.","mla":"Alpichshev, Zhanybek, et al. “Origin of the Exciton Mass in the Frustrated Mott Insulator Na2IrO3.” Physical Review B, vol. 96, no. 23, American Physical Society, 2017, doi:10.1103/PhysRevB.96.235141.","ista":"Alpichshev Z, Sie E, Mahmood F, Cao G, Gedik N. 2017. Origin of the exciton mass in the frustrated Mott insulator Na2IrO3. Physical Review B. 96(23).","chicago":"Alpichshev, Zhanybek, Edbert Sie, Fahad Mahmood, Gang Cao, and Nuh Gedik. “Origin of the Exciton Mass in the Frustrated Mott Insulator Na2IrO3.” Physical Review B. American Physical Society, 2017. https://doi.org/10.1103/PhysRevB.96.235141."},"title":"Origin of the exciton mass in the frustrated Mott insulator Na2IrO3","author":[{"orcid":"0000-0002-7183-5203","full_name":"Alpichshev, Zhanybek","last_name":"Alpichshev","first_name":"Zhanybek","id":"45E67A2A-F248-11E8-B48F-1D18A9856A87"},{"first_name":"Edbert","last_name":"Sie","full_name":"Sie, Edbert"},{"full_name":"Mahmood, Fahad","last_name":"Mahmood","first_name":"Fahad"},{"first_name":"Gang","last_name":"Cao","full_name":"Cao, Gang"},{"last_name":"Gedik","full_name":"Gedik, Nuh","first_name":"Nuh"}],"publist_id":"7436","_id":"393","status":"public","type":"journal_article","day":"26","language":[{"iso":"eng"}],"publication":"Physical Review B","year":"2017","publication_status":"published","volume":96,"issue":"23","date_published":"2017-12-26T00:00:00Z","doi":"10.1103/PhysRevB.96.235141","date_created":"2018-12-11T11:46:13Z","oa_version":"None","acknowledgement":"Z.A. gratefully acknowledges discussions with P. A. Lee and A. Kemper. A conversation with J. Zaanen was instrumental in clarifying the physical picture described in this paper. We would also like to thank A. Kogar for thoroughly reading the manuscript and making valuable comments. This work was supported by Army Research Office Grant No. W911NF-15-1-0128 and Gordon and Betty Moore Foundation EPiQS Initiative through Grant No. GBMF4540 (time resolved optical spectroscopy), Skoltech, as part of the Skoltech NGP program (theory) and National Science Foundation Grant No. DMR-1265162 (material growth).\r\n\r\n","abstract":[{"text":"We use a three-pulse ultrafast optical spectroscopy to study the relaxation processes in a frustrated Mott insulator Na2IrO3. By being able to independently produce the out-of-equilibrium bound states (excitons) of doublons and holons with the first pulse and suppress the underlying antiferromagnetic order with the second one, we were able to elucidate the relaxation mechanism of quasiparticles in this system. By observing the difference in the exciton dynamics in the magnetically ordered and disordered phases we found that the mass of this quasiparticle is mostly determined by its interaction with the surrounding spins. ","lang":"eng"}],"month":"12","intvolume":" 96","publisher":"American Physical Society","main_file_link":[{"url":"http://dspace.mit.edu/handle/1721.1/114259","open_access":"1"}],"oa":1},{"date_created":"2018-12-11T11:46:13Z","volume":95,"doi":"10.1103/PhysRevB.95.115125","issue":"11","date_published":"2017-03-13T00:00:00Z","publication_status":"published","year":"2017","publication":"Physical Review B","language":[{"iso":"eng"}],"day":"13","oa":1,"main_file_link":[{"open_access":"1","url":"http://dspace.mit.edu/handle/1721.1/109835"}],"publisher":"American Physical Society","intvolume":" 95","month":"03","abstract":[{"text":"We used femtosecond optical pump-probe spectroscopy to study the photoinduced change in reflectivity of thin films of the electron-doped cuprate La2-xCexCuO4 (LCCO) with dopings of x=0.08 (underdoped) and x=0.11 (optimally doped). Above Tc, we observe fluence-dependent relaxation rates that begin at a temperature similar to the one where transport measurements first show signatures of antiferromagnetic correlations. Upon suppressing superconductivity with a magnetic field, it is found that the fluence and temperature dependence of relaxation rates are consistent with bimolecular recombination of electrons and holes across a gap (2ΔAF) originating from antiferromagnetic correlations which comprise the pseudogap in electron-doped cuprates. This can be used to learn about coupling between electrons and high-energy (ω>2ΔAF) excitations in these compounds and set limits on the time scales on which antiferromagnetic correlations are static.","lang":"eng"}],"acknowledgement":"Optical pump-probe work was supported by the Gordon and Betty Moore Foundation's EPiQS initiative through Grant No. GBMF4540. Materials growth and characterization was supported by AFOSR FA95501410332 and NSF DMR1410665.","oa_version":"None","publist_id":"7437","author":[{"full_name":"Vishik, Inna","last_name":"Vishik","first_name":"Inna"},{"full_name":"Mahmood, Fahad","last_name":"Mahmood","first_name":"Fahad"},{"orcid":"0000-0002-7183-5203","full_name":"Alpichshev, Zhanybek","last_name":"Alpichshev","id":"45E67A2A-F248-11E8-B48F-1D18A9856A87","first_name":"Zhanybek"},{"last_name":"Gedik","full_name":"Gedik, Nuh","first_name":"Nuh"},{"first_name":"Joshu","last_name":"Higgins","full_name":"Higgins, Joshu"},{"last_name":"Greene","full_name":"Greene, Richard","first_name":"Richard"}],"title":"Ultrafast dynamics in the presence of antiferromagnetic correlations in electron doped cuprate La2 xCexCuO4±δ","date_updated":"2021-01-12T07:53:12Z","citation":{"mla":"Vishik, Inna, et al. “Ultrafast Dynamics in the Presence of Antiferromagnetic Correlations in Electron Doped Cuprate La2 XCexCuO4±δ.” Physical Review B, vol. 95, no. 11, American Physical Society, 2017, doi:10.1103/PhysRevB.95.115125.","apa":"Vishik, I., Mahmood, F., Alpichshev, Z., Gedik, N., Higgins, J., & Greene, R. (2017). Ultrafast dynamics in the presence of antiferromagnetic correlations in electron doped cuprate La2 xCexCuO4±δ. Physical Review B. American Physical Society. https://doi.org/10.1103/PhysRevB.95.115125","ama":"Vishik I, Mahmood F, Alpichshev Z, Gedik N, Higgins J, Greene R. Ultrafast dynamics in the presence of antiferromagnetic correlations in electron doped cuprate La2 xCexCuO4±δ. Physical Review B. 2017;95(11). doi:10.1103/PhysRevB.95.115125","ieee":"I. Vishik, F. Mahmood, Z. Alpichshev, N. Gedik, J. Higgins, and R. Greene, “Ultrafast dynamics in the presence of antiferromagnetic correlations in electron doped cuprate La2 xCexCuO4±δ,” Physical Review B, vol. 95, no. 11. American Physical Society, 2017.","short":"I. Vishik, F. Mahmood, Z. Alpichshev, N. Gedik, J. Higgins, R. Greene, Physical Review B 95 (2017).","chicago":"Vishik, Inna, Fahad Mahmood, Zhanybek Alpichshev, Nuh Gedik, Joshu Higgins, and Richard Greene. “Ultrafast Dynamics in the Presence of Antiferromagnetic Correlations in Electron Doped Cuprate La2 XCexCuO4±δ.” Physical Review B. American Physical Society, 2017. https://doi.org/10.1103/PhysRevB.95.115125.","ista":"Vishik I, Mahmood F, Alpichshev Z, Gedik N, Higgins J, Greene R. 2017. Ultrafast dynamics in the presence of antiferromagnetic correlations in electron doped cuprate La2 xCexCuO4±δ. Physical Review B. 95(11)."},"user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","extern":"1","type":"journal_article","status":"public","_id":"392"},{"author":[{"last_name":"Hardie","full_name":"Hardie, Rae","first_name":"Rae"},{"first_name":"Ellen","last_name":"Van Dam","full_name":"Van Dam, Ellen"},{"first_name":"Mark","last_name":"Cowley","full_name":"Cowley, Mark"},{"last_name":"Han","full_name":"Han, Ting","first_name":"Ting"},{"first_name":"Seher","last_name":"Balaban","full_name":"Balaban, Seher"},{"first_name":"Marina","full_name":"Pajic, Marina","last_name":"Pajic"},{"full_name":"Pinese, Mark","last_name":"Pinese","first_name":"Mark"},{"first_name":"Mary","full_name":"Iconomou, Mary","last_name":"Iconomou"},{"full_name":"Shearer, Robert","last_name":"Shearer","first_name":"Robert"},{"first_name":"Jessie","last_name":"Mckenna","full_name":"Mckenna, Jessie"},{"full_name":"Miller, David","last_name":"Miller","first_name":"David"},{"full_name":"Waddell, Nicola","last_name":"Waddell","first_name":"Nicola"},{"last_name":"Pearson","full_name":"Pearson, John","first_name":"John"},{"first_name":"Sean","full_name":"Grimmond, Sean","last_name":"Grimmond"},{"full_name":"Sazanov, Leonid A","orcid":"0000-0002-0977-7989","last_name":"Sazanov","id":"338D39FE-F248-11E8-B48F-1D18A9856A87","first_name":"Leonid A"},{"first_name":"Andrew","full_name":"Biankin, Andrew","last_name":"Biankin"},{"full_name":"Villas Boas, Silas","last_name":"Villas Boas","first_name":"Silas"},{"first_name":"Andrew","full_name":"Hoy, Andrew","last_name":"Hoy"},{"first_name":"Nigel","full_name":"Turner, Nigel","last_name":"Turner"},{"first_name":"Darren","full_name":"Saunders, Darren","last_name":"Saunders"}],"publist_id":"7380","title":"Mitochondrial mutations and metabolic adaptation in pancreatic cancer","citation":{"mla":"Hardie, Rae, et al. “Mitochondrial Mutations and Metabolic Adaptation in Pancreatic Cancer.” Cancer & Metabolism, vol. 5, no. 2, BioMed Central, 2017, doi:10.1186/s40170-017-0164-1.","apa":"Hardie, R., Van Dam, E., Cowley, M., Han, T., Balaban, S., Pajic, M., … Saunders, D. (2017). Mitochondrial mutations and metabolic adaptation in pancreatic cancer. Cancer & Metabolism. BioMed Central. https://doi.org/10.1186/s40170-017-0164-1","ama":"Hardie R, Van Dam E, Cowley M, et al. Mitochondrial mutations and metabolic adaptation in pancreatic cancer. Cancer & Metabolism. 2017;5(2). doi:10.1186/s40170-017-0164-1","ieee":"R. Hardie et al., “Mitochondrial mutations and metabolic adaptation in pancreatic cancer,” Cancer & Metabolism, vol. 5, no. 2. BioMed Central, 2017.","short":"R. Hardie, E. Van Dam, M. Cowley, T. Han, S. Balaban, M. Pajic, M. Pinese, M. Iconomou, R. Shearer, J. Mckenna, D. Miller, N. Waddell, J. Pearson, S. Grimmond, L.A. Sazanov, A. Biankin, S. Villas Boas, A. Hoy, N. Turner, D. Saunders, Cancer & Metabolism 5 (2017).","chicago":"Hardie, Rae, Ellen Van Dam, Mark Cowley, Ting Han, Seher Balaban, Marina Pajic, Mark Pinese, et al. “Mitochondrial Mutations and Metabolic Adaptation in Pancreatic Cancer.” Cancer & Metabolism. BioMed Central, 2017. https://doi.org/10.1186/s40170-017-0164-1.","ista":"Hardie R, Van Dam E, Cowley M, Han T, Balaban S, Pajic M, Pinese M, Iconomou M, Shearer R, Mckenna J, Miller D, Waddell N, Pearson J, Grimmond S, Sazanov LA, Biankin A, Villas Boas S, Hoy A, Turner N, Saunders D. 2017. Mitochondrial mutations and metabolic adaptation in pancreatic cancer. Cancer & Metabolism. 5(2)."},"user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","publisher":"BioMed Central","quality_controlled":"1","oa":1,"doi":"10.1186/s40170-017-0164-1","date_published":"2017-01-30T00:00:00Z","date_created":"2018-12-11T11:46:30Z","has_accepted_license":"1","year":"2017","day":"30","publication":"Cancer & Metabolism","type":"journal_article","tmp":{"legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode","image":"/images/cc_by.png","name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)","short":"CC BY (4.0)"},"status":"public","_id":"443","file_date_updated":"2020-07-14T12:46:29Z","date_updated":"2021-01-12T07:56:55Z","extern":"1","ddc":["570"],"month":"01","intvolume":" 5","abstract":[{"text":"Pancreatic cancer has a five-year survival rate of ~8%, with characteristic molecular heterogeneity and restricted treatment options. Targeting metabolism has emerged as a potentially effective therapeutic strategy for cancers such as pancreatic cancer, which are driven by genetic alterations that are not tractable drug targets. Although somatic mitochondrial genome (mtDNA) mutations have been observed in various tumors types, understanding of metabolic genotype-phenotype relationships is limited.","lang":"eng"}],"oa_version":"Published Version","volume":5,"issue":"2","publication_status":"published","file":[{"file_id":"5868","checksum":"337a65786875f64a1fe9fc0ac24767dc","content_type":"application/pdf","access_level":"open_access","relation":"main_file","date_created":"2019-01-22T08:17:56Z","file_name":"2017_Cancer_Hardie.pdf","date_updated":"2020-07-14T12:46:29Z","file_size":1609174,"creator":"dernst"}],"language":[{"iso":"eng"}]},{"publication":"Mechanisms of primary energy transduction in biology ","language":[{"iso":"eng"}],"day":"29","publication_status":"published","year":"2017","publication_identifier":{"isbn":["978-1-78262-865-1"]},"date_created":"2018-12-11T11:46:30Z","date_published":"2017-11-29T00:00:00Z","doi":"10.1039/9781788010405-00025","page":"25 - 59","oa_version":"None","abstract":[{"text":"Complex I (NADH:ubiquinone oxidoreductase) plays a central role in cellular energy generation, contributing to the proton motive force used to produce ATP. It couples the transfer of two electrons between NADH and quinone to translocation of four protons across the membrane. It is the largest protein assembly of bacterial and mitochondrial respiratory chains, composed, in mammals, of up to 45 subunits with a total molecular weight of ∼1 MDa. Bacterial enzyme is about half the size, providing the important “minimal” model of complex I. The l-shaped complex consists of a hydrophilic arm, where electron transfer occurs, and a membrane arm, where proton translocation takes place. Previously, we have solved the crystal structures of the hydrophilic domain of complex I from Thermus thermophilus and of the membrane domain from Escherichia coli, followed by the atomic structure of intact, entire complex I from T. thermophilus. Recently, we have solved by cryo-EM a first complete atomic structure of mammalian (ovine) mitochondrial complex I. Core subunits are well conserved from the bacterial version, whilst supernumerary subunits form an interlinked, stabilizing shell around the core. Subunits containing additional cofactors, including Zn ion, NADPH and phosphopantetheine, probably have regulatory roles. Dysfunction of mitochondrial complex I is implicated in many human neurodegenerative diseases. The structure of mammalian enzyme provides many insights into complex I mechanism, assembly, maturation and dysfunction, allowing detailed molecular analysis of disease-causing mutations.","lang":"eng"}],"month":"11","quality_controlled":"1","publisher":"Royal Society of Chemistry","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","citation":{"ista":"Sazanov LA. 2017.Structure of respiratory complex I: “Minimal” bacterial and “de luxe” mammalian versions. In: Mechanisms of primary energy transduction in biology . , 25–59.","chicago":"Sazanov, Leonid A. “Structure of Respiratory Complex I: ‘Minimal’ Bacterial and ‘de Luxe’ Mammalian Versions.” In Mechanisms of Primary Energy Transduction in Biology , edited by Mårten Wikström, 25–59. Mechanisms of Primary Energy Transduction in Biology . Royal Society of Chemistry, 2017. https://doi.org/10.1039/9781788010405-00025.","apa":"Sazanov, L. A. (2017). Structure of respiratory complex I: “Minimal” bacterial and “de luxe” mammalian versions. In M. Wikström (Ed.), Mechanisms of primary energy transduction in biology (pp. 25–59). Royal Society of Chemistry. https://doi.org/10.1039/9781788010405-00025","ama":"Sazanov LA. Structure of respiratory complex I: “Minimal” bacterial and “de luxe” mammalian versions. In: Wikström M, ed. Mechanisms of Primary Energy Transduction in Biology . Mechanisms of Primary Energy Transduction in Biology . Royal Society of Chemistry; 2017:25-59. doi:10.1039/9781788010405-00025","short":"L.A. Sazanov, in:, M. Wikström (Ed.), Mechanisms of Primary Energy Transduction in Biology , Royal Society of Chemistry, 2017, pp. 25–59.","ieee":"L. A. Sazanov, “Structure of respiratory complex I: ‘Minimal’ bacterial and ‘de luxe’ mammalian versions,” in Mechanisms of primary energy transduction in biology , M. Wikström, Ed. Royal Society of Chemistry, 2017, pp. 25–59.","mla":"Sazanov, Leonid A. “Structure of Respiratory Complex I: ‘Minimal’ Bacterial and ‘de Luxe’ Mammalian Versions.” Mechanisms of Primary Energy Transduction in Biology , edited by Mårten Wikström, Royal Society of Chemistry, 2017, pp. 25–59, doi:10.1039/9781788010405-00025."},"date_updated":"2021-01-12T07:56:59Z","title":"Structure of respiratory complex I: “Minimal” bacterial and “de luxe” mammalian versions","department":[{"_id":"LeSa"}],"editor":[{"full_name":"Wikström, Mårten","last_name":"Wikström","first_name":"Mårten"}],"author":[{"id":"338D39FE-F248-11E8-B48F-1D18A9856A87","first_name":"Leonid A","last_name":"Sazanov","orcid":"0000-0002-0977-7989","full_name":"Sazanov, Leonid A"}],"publist_id":"7379","series_title":"Mechanisms of Primary Energy Transduction in Biology ","_id":"444","status":"public","type":"book_chapter"},{"status":"public","type":"journal_article","_id":"445","title":"Loschmidt echo in many body localized phases","author":[{"last_name":"Serbyn","orcid":"0000-0002-2399-5827","full_name":"Maksym Serbyn","id":"47809E7E-F248-11E8-B48F-1D18A9856A87","first_name":"Maksym"},{"first_name":"Dimitry","last_name":"Abanin","full_name":"Abanin, Dimitry A"}],"publist_id":"7378","extern":1,"date_updated":"2021-01-12T07:57:03Z","citation":{"ista":"Serbyn M, Abanin D. 2017. Loschmidt echo in many body localized phases. Physical Review B - Condensed Matter and Materials Physics. 96(1).","chicago":"Serbyn, Maksym, and Dimitry Abanin. “Loschmidt Echo in Many Body Localized Phases.” Physical Review B - Condensed Matter and Materials Physics. American Physical Society, 2017. https://doi.org/10.1103/PhysRevB.96.014202.","ama":"Serbyn M, Abanin D. Loschmidt echo in many body localized phases. Physical Review B - Condensed Matter and Materials Physics. 2017;96(1). doi:10.1103/PhysRevB.96.014202","apa":"Serbyn, M., & Abanin, D. (2017). Loschmidt echo in many body localized phases. Physical Review B - Condensed Matter and Materials Physics. American Physical Society. https://doi.org/10.1103/PhysRevB.96.014202","ieee":"M. Serbyn and D. Abanin, “Loschmidt echo in many body localized phases,” Physical Review B - Condensed Matter and Materials Physics, vol. 96, no. 1. American Physical Society, 2017.","short":"M. Serbyn, D. Abanin, Physical Review B - Condensed Matter and Materials Physics 96 (2017).","mla":"Serbyn, Maksym, and Dimitry Abanin. “Loschmidt Echo in Many Body Localized Phases.” Physical Review B - Condensed Matter and Materials Physics, vol. 96, no. 1, American Physical Society, 2017, doi:10.1103/PhysRevB.96.014202."},"month":"07","intvolume":" 96","publisher":"American Physical Society","quality_controlled":0,"main_file_link":[{"open_access":"1","url":"https://arxiv.org/abs/1701.07772"}],"oa":1,"acknowledgement":"This research was supported in part by the National\nScience Foundation under Grant No. NSF PHY11-25915.\nM.S. was supported by Gordon and Betty Moore Foundation’s\nEPiQS Initiative through Grant No. GBMF4307. D.A. also\nacknowledges support by Swiss National Science Foundation.","abstract":[{"lang":"eng","text":"The Loschmidt echo, defined as the overlap between quantum wave function evolved with different Hamiltonians, quantifies the sensitivity of quantum dynamics to perturbations and is often used as a probe of quantum chaos. In this work we consider the behavior of the Loschmidt echo in the many-body localized phase, which is characterized by emergent local integrals of motion and provides a generic example of nonergodic dynamics. We demonstrate that the fluctuations of the Loschmidt echo decay as a power law in time in the many-body localized phase, in contrast to the exponential decay in few-body ergodic systems. We consider the spin-echo generalization of the Loschmidt echo and argue that the corresponding correlation function saturates to a finite value in localized systems. Slow, power-law decay of fluctuations of such spin-echo-type overlap is related to the operator spreading and is present only in the many-body localized phase, but not in a noninteracting Anderson insulator. While most of the previously considered probes of dephasing dynamics could be understood by approximating physical spin operators with local integrals of motion, the Loschmidt echo and its generalizations crucially depend on the full expansion of the physical operators via local integrals of motion operators, as well as operators which flip local integrals of motion. Hence these probes allow one to get insights into the relation between physical operators and local integrals of motion and access the operator spreading in the many-body localized phase."}],"issue":"1","volume":96,"doi":"10.1103/PhysRevB.96.014202","date_published":"2017-07-12T00:00:00Z","date_created":"2018-12-11T11:46:31Z","day":"12","publication":"Physical Review B - Condensed Matter and Materials Physics","year":"2017","publication_status":"published"},{"type":"journal_article","status":"public","_id":"452","author":[{"full_name":"Bächer, Moritz","last_name":"Bächer","first_name":"Moritz"},{"id":"49876194-F248-11E8-B48F-1D18A9856A87","first_name":"Bernd","orcid":"0000-0001-6511-9385","full_name":"Bickel, Bernd","last_name":"Bickel"},{"first_name":"Emily","full_name":"Whiting, Emily","last_name":"Whiting"},{"full_name":"Sorkine Hornung, Olga","last_name":"Sorkine Hornung","first_name":"Olga"}],"publist_id":"7370","article_processing_charge":"No","title":"Spin it: Optimizing moment of inertia for spinnable objects","citation":{"ista":"Bächer M, Bickel B, Whiting E, Sorkine Hornung O. 2017. Spin it: Optimizing moment of inertia for spinnable objects. Communications of the ACM. 60(8), 92–99.","chicago":"Bächer, Moritz, Bernd Bickel, Emily Whiting, and Olga Sorkine Hornung. “Spin It: Optimizing Moment of Inertia for Spinnable Objects.” Communications of the ACM. ACM, 2017. https://doi.org/10.1145/3068766.","apa":"Bächer, M., Bickel, B., Whiting, E., & Sorkine Hornung, O. (2017). Spin it: Optimizing moment of inertia for spinnable objects. Communications of the ACM. ACM. https://doi.org/10.1145/3068766","ama":"Bächer M, Bickel B, Whiting E, Sorkine Hornung O. Spin it: Optimizing moment of inertia for spinnable objects. Communications of the ACM. 2017;60(8):92-99. doi:10.1145/3068766","ieee":"M. Bächer, B. Bickel, E. Whiting, and O. Sorkine Hornung, “Spin it: Optimizing moment of inertia for spinnable objects,” Communications of the ACM, vol. 60, no. 8. ACM, pp. 92–99, 2017.","short":"M. Bächer, B. Bickel, E. Whiting, O. Sorkine Hornung, Communications of the ACM 60 (2017) 92–99.","mla":"Bächer, Moritz, et al. “Spin It: Optimizing Moment of Inertia for Spinnable Objects.” Communications of the ACM, vol. 60, no. 8, ACM, 2017, pp. 92–99, doi:10.1145/3068766."},"date_updated":"2022-03-18T12:55:28Z","extern":"1","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","publisher":"ACM","scopus_import":"1","month":"08","intvolume":" 60","abstract":[{"lang":"eng","text":"Spinning tops and yo-yos have long fascinated cultures around the world with their unexpected, graceful motions that seemingly elude gravity. Yet, due to the exceeding difficulty of creating stably spinning objects of asymmetric shape in a manual trial-and-error process, there has been little departure from rotationally symmetric designs. With modern 3D printing technologies, however, we can manufacture shapes of almost unbounded complexity at the press of a button, shifting this design complexity toward computation. In this article, we describe an algorithm to generate designs for spinning objects by optimizing their mass distribution: as input, the user provides a solid 3D model and a desired axis of rotation. Our approach then modifies the interior mass distribution such that the principal directions of the moment of inertia align with the target rotation frame. To create voids inside the model, we represent its volume with an adaptive multiresolution voxelization and optimize the discrete voxel fill values using a continuous, nonlinear formulation. We further optimize for rotational stability by maximizing the dominant principal moment. Our method is well-suited for a variety of 3D printed models, ranging from characters to abstract shapes. We demonstrate tops and yo-yos that spin surprisingly stably despite their asymmetric appearance."}],"oa_version":"None","acknowledgement":"This project was supported in part by the ERC Starting Grant iModel (StG-2012-306877). Emily Whiting was supported by the ETH Zurich/Marie Curie COFUND Postdoctoral Fellowship. \r\nFirst and foremost, we would like to thank our editor Steve Marschner for his invaluable feedback. We were fortunate to get further help from Maurizio Nitti for model design, Romain Prévost for Make-It-Stand comparisons, Alexander Sorkine-Hornung, Kaan Yücer, and Changil Kim for video and photo assistance, Ronnie Gänsli for metal casting, Alec Jacobson for the posed Elephant and Armadillo models, and Romain Prévost and Amit Bermano for print preparation. Model sources include: Woven Ring: generated by “Sculpture Generator 1” by Carlo H. Séquin, UC Berkeley; Elephant: De Espona model library, courtesy of Robert Sumner; T-Rex: TurboSquid; Armadillo: Stanford Computer Graphics Laboratory; and Utah Teapot: Martin Newell, University of Utah. ","page":"92 - 99","date_published":"2017-08-01T00:00:00Z","doi":"10.1145/3068766","issue":"8","volume":60,"date_created":"2018-12-11T11:46:33Z","year":"2017","publication_status":"published","day":"01","publication":"Communications of the ACM","language":[{"iso":"eng"}]},{"issue":"9","volume":113,"language":[{"iso":"eng"}],"file":[{"file_id":"5052","checksum":"99a2474088e20ac74b1882c4fbbb45b1","access_level":"open_access","relation":"main_file","content_type":"application/pdf","date_created":"2018-12-12T10:14:03Z","file_name":"IST-2018-965-v1+1_2017_Duellberg_Ensembles_of.pdf","creator":"system","date_updated":"2020-07-14T12:46:31Z","file_size":977192}],"publication_status":"published","intvolume":" 113","month":"11","oa_version":"Published Version","abstract":[{"lang":"eng","text":"Most kinesin motors move in only one direction along microtubules. Members of the kinesin-5 subfamily were initially described as unidirectional plus-end-directed motors and shown to produce piconewton forces. However, some fungal kinesin-5 motors are bidirectional. The force production of a bidirectional kinesin-5 has not yet been measured. Therefore, it remains unknown whether the mechanism of the unconventional minus-end-directed motility differs fundamentally from that of plus-end-directed stepping. Using force spectroscopy, we have measured here the forces that ensembles of purified budding yeast kinesin-5 Cin8 produce in microtubule gliding assays in both plus- and minus-end direction. Correlation analysis of pause forces demonstrated that individual Cin8 molecules produce additive forces in both directions of movement. In ensembles, Cin8 motors were able to produce single-motor forces up to a magnitude of ∼1.5 pN. Hence, these properties appear to be conserved within the kinesin-5 subfamily. Force production was largely independent of the directionality of movement, indicating similarities between the motility mechanisms for both directions. These results provide constraints for the development of models for the bidirectional motility mechanism of fission yeast kinesin-5 and provide insight into the function of this mitotic motor."}],"file_date_updated":"2020-07-14T12:46:31Z","department":[{"_id":"MaLo"}],"ddc":["570"],"date_updated":"2021-01-12T07:59:28Z","pubrep_id":"965","status":"public","tmp":{"legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode","image":"/images/cc_by.png","name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)","short":"CC BY (4.0)"},"type":"journal_article","article_type":"original","_id":"453","date_created":"2018-12-11T11:46:33Z","date_published":"2017-11-07T00:00:00Z","doi":"10.1016/j.bpj.2017.09.006","page":"2055 - 2067","publication":"Biophysical Journal","day":"07","year":"2017","has_accepted_license":"1","oa":1,"quality_controlled":"1","publisher":"Biophysical Society","acknowledgement":"The plasmid for full-length kinesin-1 was a gift from G. Holzwarth and J. Macosko with permission from J. Howard. We thank I. Lueke and N. I. Cade for technical assistance. G.P. thanks the Francis Crick Institute, and in particular the Surrey and Salbreux groups, for their hospitality during his sabbatical stay, as well as Imperial College London for making it possible. This work was supported by the Francis Crick Institute, which receives its core funding from Cancer Research UK (FC001163), the United Kingdom Medical Research Council (FC001163), and the Wellcome Trust (FC001163), and by Imperial College London. J.R. was also supported by a Sir Henry Wellcome Postdoctoral Fellowship (100145/Z/12/Z) and T.S. by the European Research Council (Advanced Grant, project 323042). ","title":"Ensembles of bidirectional kinesin Cin8 produce additive forces in both directions of movement","article_processing_charge":"No","author":[{"last_name":"Fallesen","full_name":"Fallesen, Todd","first_name":"Todd"},{"first_name":"Johanna","last_name":"Roostalu","full_name":"Roostalu, Johanna"},{"id":"459064DC-F248-11E8-B48F-1D18A9856A87","first_name":"Christian F","last_name":"Düllberg","orcid":"0000-0001-6335-9748","full_name":"Düllberg, Christian F"},{"first_name":"Gunnar","last_name":"Pruessner","full_name":"Pruessner, Gunnar"},{"last_name":"Surrey","full_name":"Surrey, Thomas","first_name":"Thomas"}],"publist_id":"7369","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","citation":{"chicago":"Fallesen, Todd, Johanna Roostalu, Christian F Düllberg, Gunnar Pruessner, and Thomas Surrey. “Ensembles of Bidirectional Kinesin Cin8 Produce Additive Forces in Both Directions of Movement.” Biophysical Journal. Biophysical Society, 2017. https://doi.org/10.1016/j.bpj.2017.09.006.","ista":"Fallesen T, Roostalu J, Düllberg CF, Pruessner G, Surrey T. 2017. Ensembles of bidirectional kinesin Cin8 produce additive forces in both directions of movement. Biophysical Journal. 113(9), 2055–2067.","mla":"Fallesen, Todd, et al. “Ensembles of Bidirectional Kinesin Cin8 Produce Additive Forces in Both Directions of Movement.” Biophysical Journal, vol. 113, no. 9, Biophysical Society, 2017, pp. 2055–67, doi:10.1016/j.bpj.2017.09.006.","apa":"Fallesen, T., Roostalu, J., Düllberg, C. F., Pruessner, G., & Surrey, T. (2017). Ensembles of bidirectional kinesin Cin8 produce additive forces in both directions of movement. Biophysical Journal. Biophysical Society. https://doi.org/10.1016/j.bpj.2017.09.006","ama":"Fallesen T, Roostalu J, Düllberg CF, Pruessner G, Surrey T. Ensembles of bidirectional kinesin Cin8 produce additive forces in both directions of movement. Biophysical Journal. 2017;113(9):2055-2067. doi:10.1016/j.bpj.2017.09.006","short":"T. Fallesen, J. Roostalu, C.F. Düllberg, G. Pruessner, T. Surrey, Biophysical Journal 113 (2017) 2055–2067.","ieee":"T. Fallesen, J. Roostalu, C. F. Düllberg, G. Pruessner, and T. Surrey, “Ensembles of bidirectional kinesin Cin8 produce additive forces in both directions of movement,” Biophysical Journal, vol. 113, no. 9. Biophysical Society, pp. 2055–2067, 2017."}},{"quality_controlled":"1","publisher":"International Federation of Computational Logic","oa":1,"date_published":"2017-09-26T00:00:00Z","doi":"10.23638/LMCS-13(3:26)2017","date_created":"2018-12-11T11:46:37Z","has_accepted_license":"1","year":"2017","day":"26","publication":"Logical Methods in Computer Science","project":[{"grant_number":"P 23499-N23","name":"Modern Graph Algorithmic Techniques in Formal Verification","_id":"2584A770-B435-11E9-9278-68D0E5697425","call_identifier":"FWF"},{"_id":"25863FF4-B435-11E9-9278-68D0E5697425","call_identifier":"FWF","grant_number":"S11407","name":"Game Theory"},{"name":"Efficient Algorithms for Computer Aided Verification","grant_number":"ICT15-003","_id":"25892FC0-B435-11E9-9278-68D0E5697425"},{"name":"Quantitative Graph Games: Theory and Applications","grant_number":"279307","call_identifier":"FP7","_id":"2581B60A-B435-11E9-9278-68D0E5697425"}],"article_number":"26","publist_id":"7357","author":[{"full_name":"Chatterjee, Krishnendu","orcid":"0000-0002-4561-241X","last_name":"Chatterjee","id":"2E5DCA20-F248-11E8-B48F-1D18A9856A87","first_name":"Krishnendu"},{"first_name":"Monika H","id":"540c9bbd-f2de-11ec-812d-d04a5be85630","last_name":"Henzinger","orcid":"0000-0002-5008-6530","full_name":"Henzinger, Monika H"},{"last_name":"Loitzenbauer","full_name":"Loitzenbauer, Veronika","first_name":"Veronika"}],"external_id":{"arxiv":["1410.0833"]},"article_processing_charge":"No","title":"Improved algorithms for parity and Streett objectives","citation":{"chicago":"Chatterjee, Krishnendu, Monika H Henzinger, and Veronika Loitzenbauer. “Improved Algorithms for Parity and Streett Objectives.” Logical Methods in Computer Science. International Federation of Computational Logic, 2017. https://doi.org/10.23638/LMCS-13(3:26)2017.","ista":"Chatterjee K, Henzinger MH, Loitzenbauer V. 2017. Improved algorithms for parity and Streett objectives. Logical Methods in Computer Science. 13(3), 26.","mla":"Chatterjee, Krishnendu, et al. “Improved Algorithms for Parity and Streett Objectives.” Logical Methods in Computer Science, vol. 13, no. 3, 26, International Federation of Computational Logic, 2017, doi:10.23638/LMCS-13(3:26)2017.","short":"K. Chatterjee, M.H. Henzinger, V. Loitzenbauer, Logical Methods in Computer Science 13 (2017).","ieee":"K. Chatterjee, M. H. Henzinger, and V. Loitzenbauer, “Improved algorithms for parity and Streett objectives,” Logical Methods in Computer Science, vol. 13, no. 3. International Federation of Computational Logic, 2017.","apa":"Chatterjee, K., Henzinger, M. H., & Loitzenbauer, V. (2017). Improved algorithms for parity and Streett objectives. Logical Methods in Computer Science. International Federation of Computational Logic. https://doi.org/10.23638/LMCS-13(3:26)2017","ama":"Chatterjee K, Henzinger MH, Loitzenbauer V. Improved algorithms for parity and Streett objectives. Logical Methods in Computer Science. 2017;13(3). doi:10.23638/LMCS-13(3:26)2017"},"user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","scopus_import":"1","month":"09","intvolume":" 13","abstract":[{"lang":"eng","text":"The computation of the winning set for parity objectives and for Streett objectives in graphs as well as in game graphs are central problems in computer-aided verification, with application to the verification of closed systems with strong fairness conditions, the verification of open systems, checking interface compatibility, well-formedness of specifications, and the synthesis of reactive systems. We show how to compute the winning set on n vertices for (1) parity-3 (aka one-pair Streett) objectives in game graphs in time O(n5/2) and for (2) k-pair Streett objectives in graphs in time O(n2+nklogn). For both problems this gives faster algorithms for dense graphs and represents the first improvement in asymptotic running time in 15 years."}],"oa_version":"Published Version","issue":"3","related_material":{"record":[{"status":"public","id":"1661","relation":"earlier_version"}]},"volume":13,"ec_funded":1,"license":"https://creativecommons.org/licenses/by-nd/4.0/","publication_identifier":{"issn":["1860-5974"]},"publication_status":"published","file":[{"file_name":"IST-2018-956-v1+1_2017_Chatterjee_Improved_algorithms.pdf","date_created":"2018-12-12T10:13:27Z","creator":"system","file_size":582940,"date_updated":"2020-07-14T12:46:32Z","file_id":"5010","checksum":"12d469ae69b80361333d7dead965cf5d","relation":"main_file","access_level":"open_access","content_type":"application/pdf"}],"language":[{"iso":"eng"}],"type":"journal_article","tmp":{"legal_code_url":"https://creativecommons.org/licenses/by-nd/4.0/legalcode","image":"/image/cc_by_nd.png","name":"Creative Commons Attribution-NoDerivatives 4.0 International (CC BY-ND 4.0)","short":"CC BY-ND (4.0)"},"status":"public","pubrep_id":"956","_id":"464","department":[{"_id":"KrCh"}],"file_date_updated":"2020-07-14T12:46:32Z","date_updated":"2023-02-23T10:08:55Z","ddc":["004"]},{"article_number":"103","project":[{"name":"Efficient Simulation of Natural Phenomena at Extremely Large Scales","grant_number":"638176","call_identifier":"H2020","_id":"2533E772-B435-11E9-9278-68D0E5697425"}],"user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","citation":{"mla":"Jeschke, Stefan, and Chris Wojtan. “Water Wave Packets.” ACM Transactions on Graphics, vol. 36, no. 4, 103, ACM, 2017, doi:10.1145/3072959.3073678.","ieee":"S. Jeschke and C. Wojtan, “Water wave packets,” ACM Transactions on Graphics, vol. 36, no. 4. ACM, 2017.","short":"S. Jeschke, C. Wojtan, ACM Transactions on Graphics 36 (2017).","ama":"Jeschke S, Wojtan C. Water wave packets. ACM Transactions on Graphics. 2017;36(4). doi:10.1145/3072959.3073678","apa":"Jeschke, S., & Wojtan, C. (2017). Water wave packets. ACM Transactions on Graphics. ACM. https://doi.org/10.1145/3072959.3073678","chicago":"Jeschke, Stefan, and Chris Wojtan. “Water Wave Packets.” ACM Transactions on Graphics. ACM, 2017. https://doi.org/10.1145/3072959.3073678.","ista":"Jeschke S, Wojtan C. 2017. Water wave packets. ACM Transactions on Graphics. 36(4), 103."},"title":"Water wave packets","article_processing_charge":"Yes (in subscription journal)","author":[{"full_name":"Jeschke, Stefan","last_name":"Jeschke","id":"44D6411A-F248-11E8-B48F-1D18A9856A87","first_name":"Stefan"},{"full_name":"Wojtan, Christopher J","orcid":"0000-0001-6646-5546","last_name":"Wojtan","id":"3C61F1D2-F248-11E8-B48F-1D18A9856A87","first_name":"Christopher J"}],"publist_id":"7350","oa":1,"publisher":"ACM","quality_controlled":"1","publication":"ACM Transactions on Graphics","day":"01","year":"2017","has_accepted_license":"1","date_created":"2018-12-11T11:46:39Z","date_published":"2017-07-01T00:00:00Z","doi":"10.1145/3072959.3073678","_id":"470","status":"public","article_type":"original","type":"journal_article","ddc":["006"],"date_updated":"2023-02-23T12:20:26Z","department":[{"_id":"ChWo"}],"file_date_updated":"2020-07-14T12:46:34Z","oa_version":"Published Version","abstract":[{"text":"This paper presents a method for simulating water surface waves as a displacement field on a 2D domain. Our method relies on Lagrangian particles that carry packets of water wave energy; each packet carries information about an entire group of wave trains, as opposed to only a single wave crest. Our approach is unconditionally stable and can simulate high resolution geometric details. This approach also presents a straightforward interface for artistic control, because it is essentially a particle system with intuitive parameters like wavelength and amplitude. Our implementation parallelizes well and runs in real time for moderately challenging scenarios.","lang":"eng"}],"acknowledged_ssus":[{"_id":"ScienComp"}],"intvolume":" 36","month":"07","scopus_import":1,"language":[{"iso":"eng"}],"file":[{"file_size":13131683,"date_updated":"2020-07-14T12:46:34Z","creator":"wojtan","file_name":"wavepackets_final.pdf","date_created":"2020-01-24T09:32:35Z","content_type":"application/pdf","relation":"main_file","access_level":"open_access","checksum":"82a3b2bfeee4ddef16ecc21675d1a48a","file_id":"7359"}],"publication_status":"published","publication_identifier":{"issn":["07300301"]},"ec_funded":1,"issue":"4","volume":36},{"quality_controlled":"1","publisher":"ACM","oa":1,"date_published":"2017-05-01T00:00:00Z","doi":"10.1145/3060139","date_created":"2018-12-11T11:46:39Z","day":"01","publication":"ACM Transactions on Computational Logic (TOCL)","year":"2017","project":[{"grant_number":"267989","name":"Quantitative Reactive Modeling","_id":"25EE3708-B435-11E9-9278-68D0E5697425","call_identifier":"FP7"},{"name":"Moderne Concurrency Paradigms","grant_number":"S11402-N23","call_identifier":"FWF","_id":"25F5A88A-B435-11E9-9278-68D0E5697425"},{"grant_number":"Z211","name":"The Wittgenstein Prize","_id":"25F42A32-B435-11E9-9278-68D0E5697425","call_identifier":"FWF"},{"call_identifier":"FP7","_id":"25681D80-B435-11E9-9278-68D0E5697425","name":"International IST Postdoc Fellowship Programme","grant_number":"291734"}],"article_number":"12","title":"Faster statistical model checking for unbounded temporal properties","author":[{"last_name":"Daca","full_name":"Daca, Przemyslaw","first_name":"Przemyslaw","id":"49351290-F248-11E8-B48F-1D18A9856A87"},{"id":"40876CD8-F248-11E8-B48F-1D18A9856A87","first_name":"Thomas A","last_name":"Henzinger","full_name":"Henzinger, Thomas A","orcid":"0000−0002−2985−7724"},{"id":"44CEF464-F248-11E8-B48F-1D18A9856A87","first_name":"Jan","orcid":"0000-0002-8122-2881","full_name":"Kretinsky, Jan","last_name":"Kretinsky"},{"full_name":"Petrov, Tatjana","orcid":"0000-0002-9041-0905","last_name":"Petrov","id":"3D5811FC-F248-11E8-B48F-1D18A9856A87","first_name":"Tatjana"}],"publist_id":"7349","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","citation":{"ista":"Daca P, Henzinger TA, Kretinsky J, Petrov T. 2017. Faster statistical model checking for unbounded temporal properties. ACM Transactions on Computational Logic (TOCL). 18(2), 12.","chicago":"Daca, Przemyslaw, Thomas A Henzinger, Jan Kretinsky, and Tatjana Petrov. “Faster Statistical Model Checking for Unbounded Temporal Properties.” ACM Transactions on Computational Logic (TOCL). ACM, 2017. https://doi.org/10.1145/3060139.","apa":"Daca, P., Henzinger, T. A., Kretinsky, J., & Petrov, T. (2017). Faster statistical model checking for unbounded temporal properties. ACM Transactions on Computational Logic (TOCL). ACM. https://doi.org/10.1145/3060139","ama":"Daca P, Henzinger TA, Kretinsky J, Petrov T. Faster statistical model checking for unbounded temporal properties. ACM Transactions on Computational Logic (TOCL). 2017;18(2). doi:10.1145/3060139","short":"P. Daca, T.A. Henzinger, J. Kretinsky, T. Petrov, ACM Transactions on Computational Logic (TOCL) 18 (2017).","ieee":"P. Daca, T. A. Henzinger, J. Kretinsky, and T. Petrov, “Faster statistical model checking for unbounded temporal properties,” ACM Transactions on Computational Logic (TOCL), vol. 18, no. 2. ACM, 2017.","mla":"Daca, Przemyslaw, et al. “Faster Statistical Model Checking for Unbounded Temporal Properties.” ACM Transactions on Computational Logic (TOCL), vol. 18, no. 2, 12, ACM, 2017, doi:10.1145/3060139."},"month":"05","intvolume":" 18","scopus_import":1,"main_file_link":[{"url":"https://arxiv.org/abs/1504.05739","open_access":"1"}],"oa_version":"Submitted Version","abstract":[{"lang":"eng","text":"We present a new algorithm for the statistical model checking of Markov chains with respect to unbounded temporal properties, including full linear temporal logic. The main idea is that we monitor each simulation run on the fly, in order to detect quickly if a bottom strongly connected component is entered with high probability, in which case the simulation run can be terminated early. As a result, our simulation runs are often much shorter than required by termination bounds that are computed a priori for a desired level of confidence on a large state space. In comparison to previous algorithms for statistical model checking our method is not only faster in many cases but also requires less information about the system, namely, only the minimum transition probability that occurs in the Markov chain. In addition, our method can be generalised to unbounded quantitative properties such as mean-payoff bounds. "}],"volume":18,"related_material":{"record":[{"relation":"earlier_version","id":"1234","status":"public"}]},"issue":"2","ec_funded":1,"language":[{"iso":"eng"}],"publication_identifier":{"issn":["15293785"]},"publication_status":"published","status":"public","type":"journal_article","_id":"471","department":[{"_id":"ToHe"}],"date_updated":"2023-02-21T16:48:11Z"},{"user_id":"3E5EF7F0-F248-11E8-B48F-1D18A9856A87","extern":"1","citation":{"short":"K. Eguchi, Z. Taoufiq, O. Thorn Seshold, D. Trauner, M. Hasegawa, T. Takahashi, European Journal of Neuroscience 37 (2017) 6043–6052.","ieee":"K. Eguchi, Z. Taoufiq, O. Thorn Seshold, D. Trauner, M. Hasegawa, and T. Takahashi, “Wild-type monomeric α-synuclein can impair vesicle endocytosis and synaptic fidelity via tubulin polymerization at the calyx of held,” European Journal of Neuroscience, vol. 37, no. 25. Wiley-Blackwell, pp. 6043–6052, 2017.","apa":"Eguchi, K., Taoufiq, Z., Thorn Seshold, O., Trauner, D., Hasegawa, M., & Takahashi, T. (2017). Wild-type monomeric α-synuclein can impair vesicle endocytosis and synaptic fidelity via tubulin polymerization at the calyx of held. European Journal of Neuroscience. Wiley-Blackwell. https://doi.org/10.1523/JNEUROSCI.0179-17.2017","ama":"Eguchi K, Taoufiq Z, Thorn Seshold O, Trauner D, Hasegawa M, Takahashi T. Wild-type monomeric α-synuclein can impair vesicle endocytosis and synaptic fidelity via tubulin polymerization at the calyx of held. European Journal of Neuroscience. 2017;37(25):6043-6052. doi:10.1523/JNEUROSCI.0179-17.2017","mla":"Eguchi, Kohgaku, et al. “Wild-Type Monomeric α-Synuclein Can Impair Vesicle Endocytosis and Synaptic Fidelity via Tubulin Polymerization at the Calyx of Held.” European Journal of Neuroscience, vol. 37, no. 25, Wiley-Blackwell, 2017, pp. 6043–52, doi:10.1523/JNEUROSCI.0179-17.2017.","ista":"Eguchi K, Taoufiq Z, Thorn Seshold O, Trauner D, Hasegawa M, Takahashi T. 2017. Wild-type monomeric α-synuclein can impair vesicle endocytosis and synaptic fidelity via tubulin polymerization at the calyx of held. European Journal of Neuroscience. 37(25), 6043–6052.","chicago":"Eguchi, Kohgaku, Zachari Taoufiq, Oliver Thorn Seshold, Dirk Trauner, Masato Hasegawa, and Tomoyuki Takahashi. “Wild-Type Monomeric α-Synuclein Can Impair Vesicle Endocytosis and Synaptic Fidelity via Tubulin Polymerization at the Calyx of Held.” European Journal of Neuroscience. Wiley-Blackwell, 2017. https://doi.org/10.1523/JNEUROSCI.0179-17.2017."},"date_updated":"2021-01-12T08:00:51Z","title":"Wild-type monomeric α-synuclein can impair vesicle endocytosis and synaptic fidelity via tubulin polymerization at the calyx of held","author":[{"last_name":"Eguchi","orcid":"0000-0002-6170-2546","full_name":"Eguchi, Kohgaku","id":"2B7846DC-F248-11E8-B48F-1D18A9856A87","first_name":"Kohgaku"},{"first_name":"Zachari","full_name":"Taoufiq, Zachari","last_name":"Taoufiq"},{"last_name":"Thorn Seshold","full_name":"Thorn Seshold, Oliver","first_name":"Oliver"},{"first_name":"Dirk","full_name":"Trauner, Dirk","last_name":"Trauner"},{"full_name":"Hasegawa, Masato","last_name":"Hasegawa","first_name":"Masato"},{"first_name":"Tomoyuki","full_name":"Takahashi, Tomoyuki","last_name":"Takahashi"}],"publist_id":"7348","_id":"472","status":"public","type":"journal_article","language":[{"iso":"eng"}],"publication":"European Journal of Neuroscience","day":"21","year":"2017","publication_status":"published","publication_identifier":{"issn":["02706474"]},"date_created":"2018-12-11T11:46:40Z","issue":"25","doi":"10.1523/JNEUROSCI.0179-17.2017","date_published":"2017-06-21T00:00:00Z","volume":37,"page":"6043 - 6052","oa_version":"None","abstract":[{"text":"α-Synuclein is a presynaptic protein the function of which has yet to be identified, but its neuronal content increases in patients of synucleinopa-thies including Parkinson’s disease. Chronic overexpression of α-synuclein reportedly expresses various phenotypes of synaptic dysfunction, but the primary target of its toxicity has not been determined. To investigate this, we acutely loaded human recombinant α-synuclein or its pathological mutants in their monomeric forms into the calyces of Held presynaptic terminals in slices from auditorily mature and immature rats of either sex. Membrane capacitance measurements revealed significant and specific inhibitory effects of WT monomeric α-synuclein on vesicle endocytosis throughout development. However, the α-synuclein A53T mutant affected vesicle endocytosis only at immature calyces, where as the A30P mutant had no effect throughout. The endocytic impairment by WTα-synuclein was rescued by intraterminal coloading of the microtubule (MT) polymerization blocker nocodazole. Furthermore, it was reversibly rescued by presynaptically loaded photostatin-1, a pho-toswitcheable inhibitor of MT polymerization, inalight-wavelength-dependent manner. Incontrast, endocyticinhibition by the A53T mutant at immature calyces was not rescued by nocodazole. Functionally, presynaptically loaded WT α-synuclein had no effect on basal synaptic transmission evoked at a low frequency, but significantly attenuated exocytosis and impaired the fidelity of neurotransmission during prolonged high-frequency stimulation. We conclude that monomeric WTα-synuclein primarily inhibits vesicle endocytosis via MT overassembly, thereby impairing high-frequency neurotransmission.","lang":"eng"}],"intvolume":" 37","month":"06","publisher":"Wiley-Blackwell","quality_controlled":"1"}]