[{"author":[{"full_name":"Bodin, C.","first_name":"C.","last_name":"Bodin"},{"full_name":"Mourad, E.","first_name":"E.","last_name":"Mourad"},{"first_name":"D.","last_name":"Zigah","full_name":"Zigah, D."},{"first_name":"S.","last_name":"Le Vot","full_name":"Le Vot, S."},{"last_name":"Freunberger","first_name":"Stefan Alexander","orcid":"0000-0003-2902-5319","id":"A8CA28E6-CE23-11E9-AD2D-EC27E6697425","full_name":"Freunberger, Stefan Alexander"},{"first_name":"F.","last_name":"Favier","full_name":"Favier, F."},{"first_name":"O.","last_name":"Fontaine","full_name":"Fontaine, O."}],"date_created":"2020-01-15T12:14:04Z","date_updated":"2021-06-10T06:17:17Z","oa_version":"None","volume":206,"user_id":"3E5EF7F0-F248-11E8-B48F-1D18A9856A87","_id":"7288","year":"2017","title":"Biredox ionic liquids: New opportunities toward high performance supercapacitors","publication_status":"published","status":"public","publisher":"Royal Society of Chemistry","intvolume":" 206","abstract":[{"lang":"eng","text":"Nowadays commercial supercapacitors are based on purely capacitive storage at the porous carbons that are used for the electrodes. However, the limits that capacitive storage imposes on energy density calls to investigate new materials to improve the capacitance of the device. This new type of electrodes (e.g., RuO2, MnO2…) involves pseudo-capacitive faradaic redox processes with the solid material. Ion exchange with solid materials is, however, much slower than the adsorption process in capacitive storage and inevitably leads to significant loss of power. Faradaic process in the liquid state, in contrast can be similarly fast as capacitive processes due to the fast ion transport. Designing new devices with liquid like dynamics and improved specific capacitance is challenging. We present a new approach to increase the specific capacitance using biredox ionic liquids, where redox moieties are tethered to the electrolyte ions, allowing high redox concentrations and significant pseudo-capacitive storage in the liquid state. Anions and cations are functionalized with anthraquinone (AQ) and 2,2,6,6-tetramethylpiperidinyl-1-oxyl (TEMPO) moieties, respectively. Glassy carbon, carbon-onion, and commercial activated carbon electrodes that exhibit different double layer structures and thus different diffusion dynamics were used to simultaneously study the electrochemical response of biredox ionic liquids at the positive and negative electrode."}],"extern":"1","type":"journal_article","doi":"10.1039/c7fd00174f","date_published":"2017-06-29T00:00:00Z","language":[{"iso":"eng"}],"publication":"Faraday Discussions","citation":{"chicago":"Bodin, C., E. Mourad, D. Zigah, S. Le Vot, Stefan Alexander Freunberger, F. Favier, and O. Fontaine. “Biredox Ionic Liquids: New Opportunities toward High Performance Supercapacitors.” Faraday Discussions. Royal Society of Chemistry, 2017. https://doi.org/10.1039/c7fd00174f.","short":"C. Bodin, E. Mourad, D. Zigah, S. Le Vot, S.A. Freunberger, F. Favier, O. Fontaine, Faraday Discussions 206 (2017) 393–404.","mla":"Bodin, C., et al. “Biredox Ionic Liquids: New Opportunities toward High Performance Supercapacitors.” Faraday Discussions, vol. 206, Royal Society of Chemistry, 2017, pp. 393–404, doi:10.1039/c7fd00174f.","ieee":"C. Bodin et al., “Biredox ionic liquids: New opportunities toward high performance supercapacitors,” Faraday Discussions, vol. 206. Royal Society of Chemistry, pp. 393–404, 2017.","apa":"Bodin, C., Mourad, E., Zigah, D., Le Vot, S., Freunberger, S. A., Favier, F., & Fontaine, O. (2017). Biredox ionic liquids: New opportunities toward high performance supercapacitors. Faraday Discussions. Royal Society of Chemistry. https://doi.org/10.1039/c7fd00174f","ista":"Bodin C, Mourad E, Zigah D, Le Vot S, Freunberger SA, Favier F, Fontaine O. 2017. Biredox ionic liquids: New opportunities toward high performance supercapacitors. Faraday Discussions. 206, 393–404.","ama":"Bodin C, Mourad E, Zigah D, et al. Biredox ionic liquids: New opportunities toward high performance supercapacitors. Faraday Discussions. 2017;206:393-404. doi:10.1039/c7fd00174f"},"quality_controlled":"1","article_type":"original","page":"393-404","month":"06","day":"29","article_processing_charge":"No","publication_identifier":{"issn":["1359-6640","1364-5498"]}},{"doi":"10.1021/acsami.7b10669","language":[{"iso":"eng"}],"oa":1,"quality_controlled":"1","publication_identifier":{"eissn":["1944-8252"],"issn":["1944-8244"]},"month":"10","author":[{"full_name":"Zach, Peter W.","first_name":"Peter W.","last_name":"Zach"},{"full_name":"Freunberger, Stefan Alexander","last_name":"Freunberger","first_name":"Stefan Alexander","orcid":"0000-0003-2902-5319","id":"A8CA28E6-CE23-11E9-AD2D-EC27E6697425"},{"first_name":"Ingo","last_name":"Klimant","full_name":"Klimant, Ingo"},{"first_name":"Sergey M.","last_name":"Borisov","full_name":"Borisov, Sergey M."}],"volume":9,"date_updated":"2021-01-12T08:12:48Z","date_created":"2020-01-15T12:15:16Z","year":"2017","publisher":"ACS","publication_status":"published","file_date_updated":"2020-07-14T12:47:55Z","extern":"1","date_published":"2017-10-10T00:00:00Z","citation":{"chicago":"Zach, Peter W., Stefan Alexander Freunberger, Ingo Klimant, and Sergey M. Borisov. “Electron-Deficient near-Infrared Pt(II) and Pd(II) Benzoporphyrins with Dual Phosphorescence and Unusually Efficient Thermally Activated Delayed Fluorescence: First Demonstration of Simultaneous Oxygen and Temperature Sensing with a Single Emitter.” ACS Applied Materials & Interfaces. ACS, 2017. https://doi.org/10.1021/acsami.7b10669.","mla":"Zach, Peter W., et al. “Electron-Deficient near-Infrared Pt(II) and Pd(II) Benzoporphyrins with Dual Phosphorescence and Unusually Efficient Thermally Activated Delayed Fluorescence: First Demonstration of Simultaneous Oxygen and Temperature Sensing with a Single Emitter.” ACS Applied Materials & Interfaces, vol. 9, no. 43, ACS, 2017, pp. 38008–23, doi:10.1021/acsami.7b10669.","short":"P.W. Zach, S.A. Freunberger, I. Klimant, S.M. Borisov, ACS Applied Materials & Interfaces 9 (2017) 38008–38023.","ista":"Zach PW, Freunberger SA, Klimant I, Borisov SM. 2017. Electron-deficient near-infrared Pt(II) and Pd(II) benzoporphyrins with dual phosphorescence and unusually efficient thermally activated delayed fluorescence: First demonstration of simultaneous oxygen and temperature sensing with a single emitter. ACS Applied Materials & Interfaces. 9(43), 38008–38023.","ieee":"P. W. Zach, S. A. Freunberger, I. Klimant, and S. M. Borisov, “Electron-deficient near-infrared Pt(II) and Pd(II) benzoporphyrins with dual phosphorescence and unusually efficient thermally activated delayed fluorescence: First demonstration of simultaneous oxygen and temperature sensing with a single emitter,” ACS Applied Materials & Interfaces, vol. 9, no. 43. ACS, pp. 38008–38023, 2017.","apa":"Zach, P. W., Freunberger, S. A., Klimant, I., & Borisov, S. M. (2017). Electron-deficient near-infrared Pt(II) and Pd(II) benzoporphyrins with dual phosphorescence and unusually efficient thermally activated delayed fluorescence: First demonstration of simultaneous oxygen and temperature sensing with a single emitter. ACS Applied Materials & Interfaces. ACS. https://doi.org/10.1021/acsami.7b10669","ama":"Zach PW, Freunberger SA, Klimant I, Borisov SM. Electron-deficient near-infrared Pt(II) and Pd(II) benzoporphyrins with dual phosphorescence and unusually efficient thermally activated delayed fluorescence: First demonstration of simultaneous oxygen and temperature sensing with a single emitter. ACS Applied Materials & Interfaces. 2017;9(43):38008-38023. doi:10.1021/acsami.7b10669"},"publication":"ACS Applied Materials & Interfaces","page":"38008-38023","article_type":"original","has_accepted_license":"1","article_processing_charge":"No","day":"10","oa_version":"Submitted Version","file":[{"date_updated":"2020-07-14T12:47:55Z","date_created":"2020-06-29T14:49:32Z","checksum":"0461c990eb910f19a70c6e5349ec35ed","file_id":"8051","relation":"main_file","creator":"sfreunbe","file_size":2072792,"content_type":"application/pdf","file_name":"Paper_Manuscript_submitted.pdf","access_level":"open_access"}],"_id":"7290","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","intvolume":" 9","title":"Electron-deficient near-infrared Pt(II) and Pd(II) benzoporphyrins with dual phosphorescence and unusually efficient thermally activated delayed fluorescence: First demonstration of simultaneous oxygen and temperature sensing with a single emitter","ddc":["540","543"],"status":"public","issue":"43","abstract":[{"lang":"eng","text":"We report a family of Pt and Pd benzoporphyrin dyes with versatile photophysical properties and easy access from cheap and abundant chemicals. Attaching 4 or 8 alkylsulfone groups onto a meso-tetraphenyltetrabenzoporphyrin (TPTBP) macrocylcle renders the dyes highly soluble in organic solvents, photostable, and electron-deficient with the redox potential raised up to 0.65 V versus the parent porphyrin. The new dyes intensively absorb in the blue (Soret band, 440–480 nm) and in the red (Q-band, 620–650 nm) parts of the electromagnetic spectrum and show bright phosphorescence at room-temperature in the NIR with quantum yields up to 30% in solution. The small singlet–triplet energy gap yields unusually efficient thermally activated delayed fluorescence (TADF) at elevated temperatures in solution and in polymeric matrices with quantum yields as high as 27% at 120 °C, which is remarkable for benzoporphyrins. Apart from oxygen sensing, these properties enable unprecedented simultaneous, self-referenced oxygen and temperature sensing with a single indicator dye: whereas oxygen can be determined either via the decay time of phosphorescence or TADF, the temperature is accessed via the ratio of the two emissions. Moreover, the dyes are efficient sensitizers for triplet–triplet annihilation (TTA)-based upconversion making possible longer sensitization wavelength than the conventional benzoporphyrin complexes. The Pt-octa-sulfone dye also features interesting semireversible transformation in basic media, which generates new NIR absorbing species."}],"type":"journal_article"},{"abstract":[{"lang":"eng","text":"Rechargeable Li–O2 batteries have amongst the highest formal energy and could store significantly more energy than other rechargeable batteries in practice if at least a large part of their promise could be realized. Realization, however, still faces many challenges than can only be overcome by fundamental understanding of the processes taking place. Here, we review recent advances in understanding the chemistry of the Li–O2 cathode and provide a perspective on dominant research needs. We put particular emphasis on issues that are often grossly misunderstood: realistic performance metrics and their reporting as well as identifying reversibility and quantitative measures to do so. Parasitic reactions are the prime obstacle for reversible cell operation and have recently been identified to be predominantly caused by singlet oxygen and not by reduced oxygen species as thought before. We discuss the far reaching implications of this finding on electrolyte and cathode stability, electrocatalysis, and future research needs."}],"issue":"10","type":"journal_article","oa_version":"Published Version","file":[{"access_level":"open_access","file_name":"2017_ChemicalScience_Mahne.pdf","creator":"dernst","file_size":992106,"content_type":"application/pdf","file_id":"7363","relation":"main_file","checksum":"70c7c2ce5430b6e8605ccbf0275f1e80","date_updated":"2020-07-14T12:47:55Z","date_created":"2020-01-26T15:04:44Z"}],"ddc":["540"],"status":"public","title":"Mechanism and performance of lithium–oxygen batteries – a perspective","intvolume":" 8","_id":"7292","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","day":"31","article_processing_charge":"No","has_accepted_license":"1","date_published":"2017-07-31T00:00:00Z","article_type":"original","page":"6716-6729","publication":"Chemical Science","citation":{"ieee":"N. Mahne, O. Fontaine, M. O. Thotiyl, M. Wilkening, and S. A. Freunberger, “Mechanism and performance of lithium–oxygen batteries – a perspective,” Chemical Science, vol. 8, no. 10. RSC, pp. 6716–6729, 2017.","apa":"Mahne, N., Fontaine, O., Thotiyl, M. O., Wilkening, M., & Freunberger, S. A. (2017). Mechanism and performance of lithium–oxygen batteries – a perspective. Chemical Science. RSC. https://doi.org/10.1039/c7sc02519j","ista":"Mahne N, Fontaine O, Thotiyl MO, Wilkening M, Freunberger SA. 2017. Mechanism and performance of lithium–oxygen batteries – a perspective. Chemical Science. 8(10), 6716–6729.","ama":"Mahne N, Fontaine O, Thotiyl MO, Wilkening M, Freunberger SA. Mechanism and performance of lithium–oxygen batteries – a perspective. Chemical Science. 2017;8(10):6716-6729. doi:10.1039/c7sc02519j","chicago":"Mahne, Nika, Olivier Fontaine, Musthafa Ottakam Thotiyl, Martin Wilkening, and Stefan Alexander Freunberger. “Mechanism and Performance of Lithium–Oxygen Batteries – a Perspective.” Chemical Science. RSC, 2017. https://doi.org/10.1039/c7sc02519j.","short":"N. Mahne, O. Fontaine, M.O. Thotiyl, M. Wilkening, S.A. Freunberger, Chemical Science 8 (2017) 6716–6729.","mla":"Mahne, Nika, et al. “Mechanism and Performance of Lithium–Oxygen Batteries – a Perspective.” Chemical Science, vol. 8, no. 10, RSC, 2017, pp. 6716–29, doi:10.1039/c7sc02519j."},"extern":"1","file_date_updated":"2020-07-14T12:47:55Z","date_created":"2020-01-15T12:15:42Z","date_updated":"2021-01-12T08:12:49Z","volume":8,"author":[{"first_name":"Nika","last_name":"Mahne","full_name":"Mahne, Nika"},{"full_name":"Fontaine, Olivier","last_name":"Fontaine","first_name":"Olivier"},{"first_name":"Musthafa Ottakam","last_name":"Thotiyl","full_name":"Thotiyl, Musthafa Ottakam"},{"full_name":"Wilkening, Martin","first_name":"Martin","last_name":"Wilkening"},{"full_name":"Freunberger, Stefan Alexander","last_name":"Freunberger","first_name":"Stefan Alexander","orcid":"0000-0003-2902-5319","id":"A8CA28E6-CE23-11E9-AD2D-EC27E6697425"}],"publication_status":"published","publisher":"RSC","year":"2017","month":"07","publication_identifier":{"issn":["2041-6520"],"eissn":["2041-6539"]},"language":[{"iso":"eng"}],"doi":"10.1039/c7sc02519j","quality_controlled":"1","oa":1,"tmp":{"name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)","legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode","short":"CC BY (4.0)","image":"/images/cc_by.png"}},{"_id":"7291","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","year":"2017","intvolume":" 10","publisher":"Wiley","title":"An electrolyte for reversible cycling of sodium metal and intercalation compounds","publication_status":"published","status":"public","author":[{"full_name":"Schafzahl, Lukas","last_name":"Schafzahl","first_name":"Lukas"},{"first_name":"Ilie","last_name":"Hanzu","full_name":"Hanzu, Ilie"},{"first_name":"Martin","last_name":"Wilkening","full_name":"Wilkening, Martin"},{"full_name":"Freunberger, Stefan Alexander","id":"A8CA28E6-CE23-11E9-AD2D-EC27E6697425","orcid":"0000-0003-2902-5319","first_name":"Stefan Alexander","last_name":"Freunberger"}],"volume":10,"oa_version":"None","date_updated":"2021-01-12T08:12:48Z","date_created":"2020-01-15T12:15:29Z","type":"journal_article","issue":"2","abstract":[{"lang":"eng","text":"Na battery chemistries show poor passivation behavior of low voltage Na storage compounds and Na metal with organic carbonate‐based electrolytes adopted from Li‐ion batteries. Therefore, a suitable electrolyte remains a major challenge for establishing Na batteries. Here we report highly concentrated sodium bis(fluorosulfonyl)imide (NaFSI) in dimethoxyethane (DME) electrolytes and investigate them for Na metal and hard carbon anodes and intercalation cathodes. For a DME/NaFSI ratio of 2, a stable passivation of anode materials was found owing to the formation of a stable solid electrolyte interface, which was characterized spectroscopically. This permitted non‐dentritic Na metal cycling with approximately 98 % coulombic efficiency as shown for up to 300 cycles. The NaFSI/DME electrolyte may enable Na‐metal anodes and allows for more reliable assessment of electrode materials in Na‐ion half‐cells, as is demonstrated by comparing half‐cell cycling of hard carbon anodes and Na3V2(PO4)3 cathodes with a widely used carbonate and the NaFSI/DME electrolyte."}],"extern":"1","citation":{"ieee":"L. Schafzahl, I. Hanzu, M. Wilkening, and S. A. Freunberger, “An electrolyte for reversible cycling of sodium metal and intercalation compounds,” ChemSusChem, vol. 10, no. 2. Wiley, pp. 401–408, 2017.","apa":"Schafzahl, L., Hanzu, I., Wilkening, M., & Freunberger, S. A. (2017). An electrolyte for reversible cycling of sodium metal and intercalation compounds. ChemSusChem. Wiley. https://doi.org/10.1002/cssc.201601222","ista":"Schafzahl L, Hanzu I, Wilkening M, Freunberger SA. 2017. An electrolyte for reversible cycling of sodium metal and intercalation compounds. ChemSusChem. 10(2), 401–408.","ama":"Schafzahl L, Hanzu I, Wilkening M, Freunberger SA. An electrolyte for reversible cycling of sodium metal and intercalation compounds. ChemSusChem. 2017;10(2):401-408. doi:10.1002/cssc.201601222","chicago":"Schafzahl, Lukas, Ilie Hanzu, Martin Wilkening, and Stefan Alexander Freunberger. “An Electrolyte for Reversible Cycling of Sodium Metal and Intercalation Compounds.” ChemSusChem. Wiley, 2017. https://doi.org/10.1002/cssc.201601222.","short":"L. Schafzahl, I. Hanzu, M. Wilkening, S.A. Freunberger, ChemSusChem 10 (2017) 401–408.","mla":"Schafzahl, Lukas, et al. “An Electrolyte for Reversible Cycling of Sodium Metal and Intercalation Compounds.” ChemSusChem, vol. 10, no. 2, Wiley, 2017, pp. 401–08, doi:10.1002/cssc.201601222."},"publication":"ChemSusChem","page":"401-408","quality_controlled":"1","article_type":"original","doi":"10.1002/cssc.201601222","date_published":"2017-01-20T00:00:00Z","language":[{"iso":"eng"}],"article_processing_charge":"No","publication_identifier":{"issn":["1864-5631"]},"month":"01","day":"20"},{"publication":"Science Translational Medicine","citation":{"short":"G. Novarino, Science Translational Medicine 9 (2017).","mla":"Novarino, Gaia. “The Science of Love in ASD and ADHD.” Science Translational Medicine, vol. 9, no. 411, eaap8168, American Association for the Advancement of Science, 2017, doi:10.1126/scitranslmed.aap8168.","chicago":"Novarino, Gaia. “The Science of Love in ASD and ADHD.” Science Translational Medicine. American Association for the Advancement of Science, 2017. https://doi.org/10.1126/scitranslmed.aap8168.","ama":"Novarino G. The science of love in ASD and ADHD. Science Translational Medicine. 2017;9(411). doi:10.1126/scitranslmed.aap8168","apa":"Novarino, G. (2017). The science of love in ASD and ADHD. Science Translational Medicine. American Association for the Advancement of Science. https://doi.org/10.1126/scitranslmed.aap8168","ieee":"G. Novarino, “The science of love in ASD and ADHD,” Science Translational Medicine, vol. 9, no. 411. American Association for the Advancement of Science, 2017.","ista":"Novarino G. 2017. The science of love in ASD and ADHD. Science Translational Medicine. 9(411), eaap8168."},"quality_controlled":"1","doi":"10.1126/scitranslmed.aap8168","date_published":"2017-10-11T00:00:00Z","language":[{"iso":"eng"}],"scopus_import":1,"day":"11","month":"10","publication_identifier":{"issn":["19466234"]},"_id":"731","year":"2017","user_id":"3E5EF7F0-F248-11E8-B48F-1D18A9856A87","title":"The science of love in ASD and ADHD","status":"public","publication_status":"published","publisher":"American Association for the Advancement of Science","intvolume":" 9","department":[{"_id":"GaNo"}],"author":[{"full_name":"Novarino, Gaia","last_name":"Novarino","first_name":"Gaia","orcid":"0000-0002-7673-7178","id":"3E57A680-F248-11E8-B48F-1D18A9856A87"}],"date_updated":"2021-01-12T08:12:57Z","date_created":"2018-12-11T11:48:12Z","volume":9,"oa_version":"None","article_number":"eaap8168","type":"journal_article","abstract":[{"text":"Genetic variations in the oxytocin receptor gene affect patients with ASD and ADHD differently.","lang":"eng"}],"issue":"411","publist_id":"6938"},{"doi":"10.1016/j.ymthe.2016.10.005","language":[{"iso":"eng"}],"tmp":{"name":"Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International (CC BY-NC-ND 4.0)","legal_code_url":"https://creativecommons.org/licenses/by-nc-nd/4.0/legalcode","short":"CC BY-NC-ND (4.0)","image":"/images/cc_by_nc_nd.png"},"oa":1,"external_id":{"pmid":["28129106"]},"quality_controlled":"1","month":"01","publication_identifier":{"issn":["1525-0016"]},"author":[{"full_name":"Smole, Anže","first_name":"Anže","last_name":"Smole"},{"last_name":"Lainšček","first_name":"Duško","full_name":"Lainšček, Duško"},{"last_name":"Bezeljak","first_name":"Urban","orcid":"0000-0003-1365-5631","id":"2A58201A-F248-11E8-B48F-1D18A9856A87","full_name":"Bezeljak, Urban"},{"full_name":"Horvat, Simon","last_name":"Horvat","first_name":"Simon"},{"full_name":"Jerala, Roman","first_name":"Roman","last_name":"Jerala"}],"date_updated":"2021-01-12T08:13:14Z","date_created":"2020-01-25T15:55:39Z","volume":25,"year":"2017","pmid":1,"publication_status":"published","publisher":"Elsevier","department":[{"_id":"MaLo"}],"file_date_updated":"2020-07-14T12:47:56Z","date_published":"2017-01-01T00:00:00Z","publication":"Molecular Therapy","citation":{"ama":"Smole A, Lainšček D, Bezeljak U, Horvat S, Jerala R. A synthetic mammalian therapeutic gene circuit for sensing and suppressing inflammation. Molecular Therapy. 2017;25(1):102-119. doi:10.1016/j.ymthe.2016.10.005","ista":"Smole A, Lainšček D, Bezeljak U, Horvat S, Jerala R. 2017. A synthetic mammalian therapeutic gene circuit for sensing and suppressing inflammation. Molecular Therapy. 25(1), 102–119.","ieee":"A. Smole, D. Lainšček, U. Bezeljak, S. Horvat, and R. Jerala, “A synthetic mammalian therapeutic gene circuit for sensing and suppressing inflammation,” Molecular Therapy, vol. 25, no. 1. Elsevier, pp. 102–119, 2017.","apa":"Smole, A., Lainšček, D., Bezeljak, U., Horvat, S., & Jerala, R. (2017). A synthetic mammalian therapeutic gene circuit for sensing and suppressing inflammation. Molecular Therapy. Elsevier. https://doi.org/10.1016/j.ymthe.2016.10.005","mla":"Smole, Anže, et al. “A Synthetic Mammalian Therapeutic Gene Circuit for Sensing and Suppressing Inflammation.” Molecular Therapy, vol. 25, no. 1, Elsevier, 2017, pp. 102–19, doi:10.1016/j.ymthe.2016.10.005.","short":"A. Smole, D. Lainšček, U. Bezeljak, S. Horvat, R. Jerala, Molecular Therapy 25 (2017) 102–119.","chicago":"Smole, Anže, Duško Lainšček, Urban Bezeljak, Simon Horvat, and Roman Jerala. “A Synthetic Mammalian Therapeutic Gene Circuit for Sensing and Suppressing Inflammation.” Molecular Therapy. Elsevier, 2017. https://doi.org/10.1016/j.ymthe.2016.10.005."},"article_type":"original","page":"102-119","day":"01","has_accepted_license":"1","article_processing_charge":"No","oa_version":"Published Version","file":[{"access_level":"open_access","file_name":"2017_MolecularTherapy_Smole.pdf","creator":"dernst","content_type":"application/pdf","file_size":3404806,"file_id":"7561","relation":"main_file","checksum":"ea8b1b28606dd1edab7379ba4fa3641f","date_created":"2020-03-03T10:55:13Z","date_updated":"2020-07-14T12:47:56Z"}],"user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","_id":"7360","ddc":["570"],"status":"public","title":"A synthetic mammalian therapeutic gene circuit for sensing and suppressing inflammation","intvolume":" 25","abstract":[{"lang":"eng","text":"Inflammation, which is a highly regulated host response against danger signals, may be harmful if it is excessive and deregulated. Ideally, anti-inflammatory therapy should autonomously commence as soon as possible after the onset of inflammation, should be controllable by a physician, and should not systemically block beneficial immune response in the long term. We describe a genetically encoded anti-inflammatory mammalian cell device based on a modular engineered genetic circuit comprising a sensor, an amplifier, a “thresholder” to restrict activation of a positive-feedback loop, a combination of advanced clinically used biopharmaceutical proteins, and orthogonal regulatory elements that linked modules into the functional device. This genetic circuit was autonomously activated by inflammatory signals, including endogenous cecal ligation and puncture (CLP)-induced inflammation in mice and serum from a systemic juvenile idiopathic arthritis (sIJA) patient, and could be reset externally by a chemical signal. The microencapsulated anti-inflammatory device significantly reduced the pathology in dextran sodium sulfate (DSS)-induced acute murine colitis, demonstrating a synthetic immunological approach for autonomous anti-inflammatory therapy."}],"issue":"1","type":"journal_article"},{"type":"book_chapter","alternative_title":["Canadiana"],"abstract":[{"lang":"eng","text":"The essay focuses on individual and collective forms of liminality in John Marlyn’s Under the Ribs of Death. Set in early twentieth-century Winnipeg, the 1957 immigrant novel explores liminal experiences related to ethnic identity, male sexuality, social class, urban spaces and turbulent economic times. As the son of a poor working-class family from Hungary, Sandor Hunyadi makes every effort to become a true Canadian and a successful businessman, but, no matter how hard he tries to overcome contemporary ethnic prejudices and economic hardships, his personal and professional life remains in liminality. In other words, the protagonist undergoes separation, fails at incorporation, and becomes stuck in transition."}],"publist_id":"6909","extern":1,"year":"2017","_id":"748","title":"'...beyond the invisible barrier at Portage and Main': Liminality in John Marlyn's Under the Ribs of Death","status":"public","publication_status":"published","publisher":"Peter Lang GmbH","editor":[{"last_name":"Brandt","first_name":"Stefan","full_name":"Brandt, Stefan L."}],"author":[{"full_name":"Bernhard Wenzl","id":"479E9046-F248-11E8-B48F-1D18A9856A87","first_name":"Bernhard","last_name":"Wenzl"}],"date_updated":"2021-01-12T08:13:49Z","date_created":"2018-12-11T11:48:18Z","day":"01","month":"12","publication":"In-Between - Liminal Spaces in Canadian Literature and Culture","citation":{"mla":"Wenzl, Bernhard. “‘...Beyond the Invisible Barrier at Portage and Main’: Liminality in John Marlyn’s Under the Ribs of Death.” In-Between - Liminal Spaces in Canadian Literature and Culture, edited by Stefan Brandt, Peter Lang GmbH, 2017, pp. 91–100, doi:10.3726/b11899.","short":"B. Wenzl, in:, S. Brandt (Ed.), In-Between - Liminal Spaces in Canadian Literature and Culture, Peter Lang GmbH, 2017, pp. 91–100.","chicago":"Wenzl, Bernhard. “‘...Beyond the Invisible Barrier at Portage and Main’: Liminality in John Marlyn’s Under the Ribs of Death.” In In-Between - Liminal Spaces in Canadian Literature and Culture, edited by Stefan Brandt, 91–100. Peter Lang GmbH, 2017. https://doi.org/10.3726/b11899.","ama":"Wenzl B. “...beyond the invisible barrier at Portage and Main”: Liminality in John Marlyn’s Under the Ribs of Death. In: Brandt S, ed. In-Between - Liminal Spaces in Canadian Literature and Culture. Peter Lang GmbH; 2017:91-100. doi:10.3726/b11899","ista":"Wenzl B. 2017.‘...beyond the invisible barrier at Portage and Main’: Liminality in John Marlyn’s Under the Ribs of Death. In: In-Between - Liminal Spaces in Canadian Literature and Culture. Canadiana, , 91–100.","apa":"Wenzl, B. (2017). “...beyond the invisible barrier at Portage and Main”: Liminality in John Marlyn’s Under the Ribs of Death. In S. Brandt (Ed.), In-Between - Liminal Spaces in Canadian Literature and Culture (pp. 91–100). Peter Lang GmbH. https://doi.org/10.3726/b11899","ieee":"B. Wenzl, “‘...beyond the invisible barrier at Portage and Main’: Liminality in John Marlyn’s Under the Ribs of Death,” in In-Between - Liminal Spaces in Canadian Literature and Culture, S. Brandt, Ed. Peter Lang GmbH, 2017, pp. 91–100."},"quality_controlled":0,"page":"91 - 100","date_published":"2017-12-01T00:00:00Z","doi":"10.3726/b11899"},{"author":[{"full_name":"Pielorz, Jasmin","id":"49BC895A-F248-11E8-B48F-1D18A9856A87","first_name":"Jasmin","last_name":"Pielorz"},{"full_name":"Prandtstetter, Matthias","last_name":"Prandtstetter","first_name":"Matthias"},{"last_name":"Straub","first_name":"Markus","full_name":"Straub, Markus"},{"full_name":"Lampert, Christoph","id":"40C20FD2-F248-11E8-B48F-1D18A9856A87","orcid":"0000-0001-8622-7887","first_name":"Christoph","last_name":"Lampert"}],"oa_version":"None","date_updated":"2021-01-12T08:13:55Z","date_created":"2018-12-11T11:48:18Z","_id":"750","year":"2017","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","publisher":"IEEE","department":[{"_id":"ChLa"}],"title":"Optimal geospatial volunteer allocation needs realistic distances","publication_status":"published","status":"public","publist_id":"6906","abstract":[{"lang":"eng","text":"Modern communication technologies allow first responders to contact thousands of potential volunteers simultaneously for support during a crisis or disaster event. However, such volunteer efforts must be well coordinated and monitored, in order to offer an effective relief to the professionals. In this paper we extend earlier work on optimally assigning volunteers to selected landmark locations. In particular, we emphasize the aspect that obtaining good assignments requires not only advanced computational tools, but also a realistic measure of distance between volunteers and landmarks. Specifically, we propose the use of the Open Street Map (OSM) driving distance instead of he previously used flight distance. We find the OSM driving distance to be better aligned with the interests of volunteers and first responders. Furthermore, we show that relying on the flying distance leads to a substantial underestimation of the number of required volunteers, causing negative side effects in case of an actual crisis situation."}],"type":"conference","date_published":"2017-12-01T00:00:00Z","doi":"10.1109/BigData.2017.8258375","conference":{"name":"Big Data","start_date":"2017-12-11","location":"Boston, MA, United States","end_date":"2017-12-14"},"language":[{"iso":"eng"}],"citation":{"ama":"Pielorz J, Prandtstetter M, Straub M, Lampert C. Optimal geospatial volunteer allocation needs realistic distances. In: 2017 IEEE International Conference on Big Data. IEEE; 2017:3760-3763. doi:10.1109/BigData.2017.8258375","apa":"Pielorz, J., Prandtstetter, M., Straub, M., & Lampert, C. (2017). Optimal geospatial volunteer allocation needs realistic distances. In 2017 IEEE International Conference on Big Data (pp. 3760–3763). Boston, MA, United States: IEEE. https://doi.org/10.1109/BigData.2017.8258375","ieee":"J. Pielorz, M. Prandtstetter, M. Straub, and C. Lampert, “Optimal geospatial volunteer allocation needs realistic distances,” in 2017 IEEE International Conference on Big Data, Boston, MA, United States, 2017, pp. 3760–3763.","ista":"Pielorz J, Prandtstetter M, Straub M, Lampert C. 2017. Optimal geospatial volunteer allocation needs realistic distances. 2017 IEEE International Conference on Big Data. Big Data, 3760–3763.","short":"J. Pielorz, M. Prandtstetter, M. Straub, C. Lampert, in:, 2017 IEEE International Conference on Big Data, IEEE, 2017, pp. 3760–3763.","mla":"Pielorz, Jasmin, et al. “Optimal Geospatial Volunteer Allocation Needs Realistic Distances.” 2017 IEEE International Conference on Big Data, IEEE, 2017, pp. 3760–63, doi:10.1109/BigData.2017.8258375.","chicago":"Pielorz, Jasmin, Matthias Prandtstetter, Markus Straub, and Christoph Lampert. “Optimal Geospatial Volunteer Allocation Needs Realistic Distances.” In 2017 IEEE International Conference on Big Data, 3760–63. IEEE, 2017. https://doi.org/10.1109/BigData.2017.8258375."},"publication":"2017 IEEE International Conference on Big Data","page":"3760 - 3763","quality_controlled":"1","publication_identifier":{"isbn":["978-153862714-3"]},"month":"12","day":"01","scopus_import":1},{"extern":"1","abstract":[{"text":"Meta-analyses of genome-wide association studies, which dominate genetic discovery, are based on data from diverse historical time periods and populations. Genetic scores derived from genome-wide association studies explain only a fraction of the heritability estimates obtained from whole-genome studies on single populations, known as the ‘hidden heritability’ puzzle. Using seven sampling populations (n = 35,062), we test whether hidden heritability is attributed to heterogeneity across sampling populations and time, showing that estimates are substantially smaller across populations compared with within populations. We show that the hidden heritability varies substantially: from zero for height to 20% for body mass index, 37% for education, 40% for age at first birth and up to 75% for number of children. Simulations demonstrate that our results are more likely to reflect heterogeneity in phenotypic measurement or gene–environment interactions than genetic heterogeneity. These findings have substantial implications for genetic discovery, suggesting that large homogenous datasets are required for behavioural phenotypes and that gene–environment interaction may be a central challenge for genetic discovery.","lang":"eng"}],"issue":"10","type":"journal_article","date_updated":"2021-01-12T08:15:08Z","date_created":"2020-04-30T10:47:02Z","volume":1,"oa_version":"None","author":[{"full_name":"Tropf, Felix C.","last_name":"Tropf","first_name":"Felix C."},{"first_name":"S. Hong","last_name":"Lee","full_name":"Lee, S. Hong"},{"first_name":"Renske M.","last_name":"Verweij","full_name":"Verweij, Renske M."},{"last_name":"Stulp","first_name":"Gert","full_name":"Stulp, Gert"},{"full_name":"van der Most, Peter J.","last_name":"van der Most","first_name":"Peter J."},{"full_name":"de Vlaming, Ronald","last_name":"de Vlaming","first_name":"Ronald"},{"full_name":"Bakshi, Andrew","first_name":"Andrew","last_name":"Bakshi"},{"last_name":"Briley","first_name":"Daniel A.","full_name":"Briley, Daniel A."},{"last_name":"Rahal","first_name":"Charles","full_name":"Rahal, Charles"},{"full_name":"Hellpap, Robert","last_name":"Hellpap","first_name":"Robert"},{"last_name":"Iliadou","first_name":"Anastasia N.","full_name":"Iliadou, Anastasia N."},{"full_name":"Esko, Tõnu","last_name":"Esko","first_name":"Tõnu"},{"last_name":"Metspalu","first_name":"Andres","full_name":"Metspalu, Andres"},{"full_name":"Medland, Sarah E.","last_name":"Medland","first_name":"Sarah E."},{"full_name":"Martin, Nicholas G.","first_name":"Nicholas G.","last_name":"Martin"},{"full_name":"Barban, Nicola","last_name":"Barban","first_name":"Nicola"},{"full_name":"Snieder, Harold","last_name":"Snieder","first_name":"Harold"},{"full_name":"Robinson, Matthew Richard","id":"E5D42276-F5DA-11E9-8E24-6303E6697425","orcid":"0000-0001-8982-8813","first_name":"Matthew Richard","last_name":"Robinson"},{"full_name":"Mills, Melinda C.","first_name":"Melinda C.","last_name":"Mills"}],"title":"Hidden heritability due to heterogeneity across seven populations","publication_status":"published","status":"public","publisher":"Springer Nature","intvolume":" 1","_id":"7728","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","year":"2017","month":"09","day":"11","article_processing_charge":"No","publication_identifier":{"issn":["2397-3374"]},"language":[{"iso":"eng"}],"date_published":"2017-09-11T00:00:00Z","doi":"10.1038/s41562-017-0195-1","quality_controlled":"1","article_type":"original","page":"757-765","publication":"Nature Human Behaviour","citation":{"ama":"Tropf FC, Lee SH, Verweij RM, et al. Hidden heritability due to heterogeneity across seven populations. Nature Human Behaviour. 2017;1(10):757-765. doi:10.1038/s41562-017-0195-1","apa":"Tropf, F. C., Lee, S. H., Verweij, R. M., Stulp, G., van der Most, P. J., de Vlaming, R., … Mills, M. C. (2017). Hidden heritability due to heterogeneity across seven populations. Nature Human Behaviour. Springer Nature. https://doi.org/10.1038/s41562-017-0195-1","ieee":"F. C. Tropf et al., “Hidden heritability due to heterogeneity across seven populations,” Nature Human Behaviour, vol. 1, no. 10. Springer Nature, pp. 757–765, 2017.","ista":"Tropf FC, Lee SH, Verweij RM, Stulp G, van der Most PJ, de Vlaming R, Bakshi A, Briley DA, Rahal C, Hellpap R, Iliadou AN, Esko T, Metspalu A, Medland SE, Martin NG, Barban N, Snieder H, Robinson MR, Mills MC. 2017. Hidden heritability due to heterogeneity across seven populations. Nature Human Behaviour. 1(10), 757–765.","short":"F.C. Tropf, S.H. Lee, R.M. Verweij, G. Stulp, P.J. van der Most, R. de Vlaming, A. Bakshi, D.A. Briley, C. Rahal, R. Hellpap, A.N. Iliadou, T. Esko, A. Metspalu, S.E. Medland, N.G. Martin, N. Barban, H. Snieder, M.R. Robinson, M.C. Mills, Nature Human Behaviour 1 (2017) 757–765.","mla":"Tropf, Felix C., et al. “Hidden Heritability Due to Heterogeneity across Seven Populations.” Nature Human Behaviour, vol. 1, no. 10, Springer Nature, 2017, pp. 757–65, doi:10.1038/s41562-017-0195-1.","chicago":"Tropf, Felix C., S. Hong Lee, Renske M. Verweij, Gert Stulp, Peter J. van der Most, Ronald de Vlaming, Andrew Bakshi, et al. “Hidden Heritability Due to Heterogeneity across Seven Populations.” Nature Human Behaviour. Springer Nature, 2017. https://doi.org/10.1038/s41562-017-0195-1."}},{"month":"12","publication_identifier":{"issn":["0962-8452","1471-2954"]},"quality_controlled":"1","external_id":{"pmid":["29212724"]},"language":[{"iso":"eng"}],"doi":"10.1098/rspb.2017.1824","article_number":"20171824","extern":"1","publication_status":"published","publisher":"The Royal Society","year":"2017","pmid":1,"date_created":"2020-04-30T10:46:43Z","date_updated":"2021-01-12T08:15:08Z","volume":284,"author":[{"full_name":"Burger, D.","last_name":"Burger","first_name":"D."},{"full_name":"Thomas, S.","first_name":"S.","last_name":"Thomas"},{"full_name":"Aepli, H.","first_name":"H.","last_name":"Aepli"},{"last_name":"Dreyer","first_name":"M.","full_name":"Dreyer, M."},{"last_name":"Fabre","first_name":"G.","full_name":"Fabre, G."},{"last_name":"Marti","first_name":"E.","full_name":"Marti, E."},{"first_name":"H.","last_name":"Sieme","full_name":"Sieme, H."},{"full_name":"Robinson, Matthew Richard","orcid":"0000-0001-8982-8813","id":"E5D42276-F5DA-11E9-8E24-6303E6697425","last_name":"Robinson","first_name":"Matthew Richard"},{"last_name":"Wedekind","first_name":"C.","full_name":"Wedekind, C."}],"day":"06","article_processing_charge":"No","article_type":"original","publication":"Proceedings of the Royal Society B: Biological Sciences","citation":{"chicago":"Burger, D., S. Thomas, H. Aepli, M. Dreyer, G. Fabre, E. Marti, H. Sieme, Matthew Richard Robinson, and C. Wedekind. “Major Histocompatibility Complex-Linked Social Signalling Affects Female Fertility.” Proceedings of the Royal Society B: Biological Sciences. The Royal Society, 2017. https://doi.org/10.1098/rspb.2017.1824.","short":"D. Burger, S. Thomas, H. Aepli, M. Dreyer, G. Fabre, E. Marti, H. Sieme, M.R. Robinson, C. Wedekind, Proceedings of the Royal Society B: Biological Sciences 284 (2017).","mla":"Burger, D., et al. “Major Histocompatibility Complex-Linked Social Signalling Affects Female Fertility.” Proceedings of the Royal Society B: Biological Sciences, vol. 284, no. 1868, 20171824, The Royal Society, 2017, doi:10.1098/rspb.2017.1824.","ieee":"D. Burger et al., “Major histocompatibility complex-linked social signalling affects female fertility,” Proceedings of the Royal Society B: Biological Sciences, vol. 284, no. 1868. The Royal Society, 2017.","apa":"Burger, D., Thomas, S., Aepli, H., Dreyer, M., Fabre, G., Marti, E., … Wedekind, C. (2017). Major histocompatibility complex-linked social signalling affects female fertility. Proceedings of the Royal Society B: Biological Sciences. The Royal Society. https://doi.org/10.1098/rspb.2017.1824","ista":"Burger D, Thomas S, Aepli H, Dreyer M, Fabre G, Marti E, Sieme H, Robinson MR, Wedekind C. 2017. Major histocompatibility complex-linked social signalling affects female fertility. Proceedings of the Royal Society B: Biological Sciences. 284(1868), 20171824.","ama":"Burger D, Thomas S, Aepli H, et al. Major histocompatibility complex-linked social signalling affects female fertility. Proceedings of the Royal Society B: Biological Sciences. 2017;284(1868). doi:10.1098/rspb.2017.1824"},"date_published":"2017-12-06T00:00:00Z","type":"journal_article","abstract":[{"text":"Genes of the major histocompatibility complex (MHC) have been shown to influence social signalling and mate preferences in many species, including humans. First observations suggest that MHC signalling may also affect female fertility. To test this hypothesis, we exposed 191 female horses (Equus caballus) to either an MHC-similar or an MHC-dissimilar stimulus male around the time of ovulation and conception. A within-subject experimental design controlled for non-MHC-linked male characteristics, and instrumental insemination with semen of other males (n = 106) controlled for potential confounding effects of semen or embryo characteristics. We found that females were more likely to become pregnant if exposed to an MHC-dissimilar than to an MHC-similar male, while overall genetic distance to the stimulus males (based on microsatellite markers on 20 chromosomes) had no effect. Our results demonstrate that early pregnancy failures can be due to maternal life-history decisions (cryptic female choice) influenced by MHC-linked social signalling.","lang":"eng"}],"issue":"1868","title":"Major histocompatibility complex-linked social signalling affects female fertility","status":"public","intvolume":" 284","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","_id":"7727","oa_version":"None"}]