---
_id: '2962'
abstract:
- lang: eng
text: The choice of summary statistics is a crucial step in approximate Bayesian
computation (ABC). Since statistics are often not sufficient, this choice involves
a trade-off between loss of information and reduction of dimensionality. The latter
may increase the efficiency of ABC. Here, we propose an approach for choosing
summary statistics based on boosting, a technique from the machine learning literature.
We consider different types of boosting and compare them to partial least squares
regression as an alternative. To mitigate the lack of sufficiency, we also propose
an approach for choosing summary statistics locally, in the putative neighborhood
of the true parameter value. We study a demographic model motivated by the re-introduction
of Alpine ibex (Capra ibex) into the Swiss Alps. The parameters of interest are
the mean and standard deviation across microsatellites of the scaled ancestral
mutation rate (θanc = 4 Ne u), and the proportion of males obtaining access to
matings per breeding season (ω). By simulation, we assess the properties of the
posterior distribution obtained with the various methods. According to our criteria,
ABC with summary statistics chosen locally via boosting with the L2-loss performs
best. Applying that method to the ibex data, we estimate θanc ≈ 1.288, and find
that most of the variation across loci of the ancestral mutation rate u is between
7.7×10−4 and 3.5×10−3 per locus per generation. The proportion of males with access
to matings is estimated to ω ≈ 0.21, which is in good agreement with recent independent
estimates.
acknowledged_ssus:
- _id: ScienComp
author:
- first_name: Simon
full_name: Aeschbacher, Simon
id: 2D35326E-F248-11E8-B48F-1D18A9856A87
last_name: Aeschbacher
- first_name: Mark
full_name: Beaumont, Mark
last_name: Beaumont
- first_name: Andreas
full_name: Futschik, Andreas
last_name: Futschik
citation:
ama: Aeschbacher S, Beaumont M, Futschik A. A novel approach for choosing summary
statistics in approximate Bayesian computation. Genetics. 2012;192(3):1027-1047.
doi:10.1534/genetics.112.143164
apa: Aeschbacher, S., Beaumont, M., & Futschik, A. (2012). A novel approach
for choosing summary statistics in approximate Bayesian computation. Genetics.
Genetics Society of America. https://doi.org/10.1534/genetics.112.143164
chicago: Aeschbacher, Simon, Mark Beaumont, and Andreas Futschik. “A Novel Approach
for Choosing Summary Statistics in Approximate Bayesian Computation.” Genetics.
Genetics Society of America, 2012. https://doi.org/10.1534/genetics.112.143164.
ieee: S. Aeschbacher, M. Beaumont, and A. Futschik, “A novel approach for choosing
summary statistics in approximate Bayesian computation,” Genetics, vol.
192, no. 3. Genetics Society of America, pp. 1027–1047, 2012.
ista: Aeschbacher S, Beaumont M, Futschik A. 2012. A novel approach for choosing
summary statistics in approximate Bayesian computation. Genetics. 192(3), 1027–1047.
mla: Aeschbacher, Simon, et al. “A Novel Approach for Choosing Summary Statistics
in Approximate Bayesian Computation.” Genetics, vol. 192, no. 3, Genetics
Society of America, 2012, pp. 1027–47, doi:10.1534/genetics.112.143164.
short: S. Aeschbacher, M. Beaumont, A. Futschik, Genetics 192 (2012) 1027–1047.
date_created: 2018-12-11T12:00:34Z
date_published: 2012-11-01T00:00:00Z
date_updated: 2021-01-12T07:40:05Z
day: '01'
department:
- _id: NiBa
doi: 10.1534/genetics.112.143164
external_id:
pmid:
- '22960215'
intvolume: ' 192'
issue: '3'
language:
- iso: eng
main_file_link:
- open_access: '1'
url: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3522150/
month: '11'
oa: 1
oa_version: Submitted Version
page: 1027 - 1047
pmid: 1
publication: Genetics
publication_status: published
publisher: Genetics Society of America
publist_id: '3763'
quality_controlled: '1'
scopus_import: 1
status: public
title: A novel approach for choosing summary statistics in approximate Bayesian computation
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 192
year: '2012'
...
---
_id: '2965'
abstract:
- lang: eng
text: Dieser Artikel soll die sechs verschiedenen Creative Commons Lizenzen erläutern
und ihre Bedeutung im Rahmen des wissenschaftlichen Publizierens und des Open
Access erklären (CC-BY, CC-BY-SA, CC-BY-NC, CC-BY-ND, CC-BYNC-SA, CC-BY-NC-ND).
author:
- first_name: Patrick
full_name: Danowski, Patrick
id: 2EBD1598-F248-11E8-B48F-1D18A9856A87
last_name: Danowski
orcid: 0000-0002-6026-4409
citation:
ama: 'Danowski P. Kontext Open Access: Creative Commons. Mitteilungen der Vereinigung
Österreichischer Bibliothekarinnen & Bibliothekare. 2012;65(2):200-212.'
apa: 'Danowski, P. (2012). Kontext Open Access: Creative Commons. Mitteilungen
der Vereinigung Österreichischer Bibliothekarinnen & Bibliothekare. VÖB.'
chicago: 'Danowski, Patrick. “Kontext Open Access: Creative Commons.” Mitteilungen
der Vereinigung Österreichischer Bibliothekarinnen & Bibliothekare. VÖB,
2012.'
ieee: 'P. Danowski, “Kontext Open Access: Creative Commons,” Mitteilungen der
Vereinigung Österreichischer Bibliothekarinnen & Bibliothekare, vol. 65,
no. 2. VÖB, pp. 200–212, 2012.'
ista: 'Danowski P. 2012. Kontext Open Access: Creative Commons. Mitteilungen der
Vereinigung Österreichischer Bibliothekarinnen & Bibliothekare. 65(2), 200–212.'
mla: 'Danowski, Patrick. “Kontext Open Access: Creative Commons.” Mitteilungen
der Vereinigung Österreichischer Bibliothekarinnen & Bibliothekare, vol.
65, no. 2, VÖB, 2012, pp. 200–12.'
short: P. Danowski, Mitteilungen der Vereinigung Österreichischer Bibliothekarinnen
& Bibliothekare 65 (2012) 200–212.
date_created: 2018-12-11T12:00:35Z
date_published: 2012-09-01T00:00:00Z
date_updated: 2021-01-12T07:40:07Z
day: '01'
ddc:
- '020'
department:
- _id: E-Lib
file:
- access_level: open_access
checksum: 162eea47d9d840c26b496ba6ae4d1c09
content_type: application/pdf
creator: system
date_created: 2018-12-12T10:08:42Z
date_updated: 2020-07-14T12:45:57Z
file_id: '4703'
file_name: IST-2012-95-v1+1_sp-beitrag_danowski_kontext_open_access_creative_commons.pdf
file_size: 503345
relation: main_file
file_date_updated: 2020-07-14T12:45:57Z
has_accepted_license: '1'
intvolume: ' 65'
issue: '2'
language:
- iso: ger
main_file_link:
- open_access: '1'
url: ' http://hdl.handle.net/10760/17625'
month: '09'
oa: 1
oa_version: Published Version
page: 200 - 212
popular_science: '1'
publication: Mitteilungen der Vereinigung Österreichischer Bibliothekarinnen & Bibliothekare
publication_status: published
publisher: VÖB
publist_id: '3754'
pubrep_id: '95'
scopus_import: 1
status: public
title: 'Kontext Open Access: Creative Commons'
tmp:
image: /images/cc_by.png
legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
short: CC BY (4.0)
type: journal_article
user_id: 3E5EF7F0-F248-11E8-B48F-1D18A9856A87
volume: 65
year: '2012'
...
---
_id: '2963'
abstract:
- lang: eng
text: 'Zebra finches are an ubiquitous model system for the study of vocal learning
in animal communication. Their song has been well described, but its possible
function(s) in social communication are only partly understood. The so-called
‘directed song’ is a high-intensity, high-performance song given during courtship
in close proximity to the female, which is known to mediate mate choice and mating.
However, this singing mode constitutes only a fraction of zebra finch males’ prolific
song output. Potential communicative functions of their second, ‘undirected’ singing
mode remain unresolved in the face of contradicting reports of both facilitating
and inhibiting effects of social company on singing. We addressed this issue by
experimentally manipulating social contexts in a within-subject design, comparing
a solo versus male or female only company condition, each lasting for 24 hours.
Males’ total song output was significantly higher when a conspecific was in audible
and visible distance than when they were alone. Male and female company had an
equally facilitating effect on song output. Our findings thus indicate that singing
motivation is facilitated rather than inhibited by social company, suggesting
that singing in zebra finches might function both in inter- and intrasexual communication. '
author:
- first_name: Fabienne
full_name: Jesse, Fabienne
id: 4C8C26A4-F248-11E8-B48F-1D18A9856A87
last_name: Jesse
- first_name: Katharina
full_name: Riebel, Katharina
last_name: Riebel
citation:
ama: Jesse F, Riebel K. Social facilitation of male song by male and female conspecifics
in the zebra finch, Taeniopygia guttata. Behavioural Processes. 2012;91(3):262-266.
doi:10.1016/j.beproc.2012.09.006
apa: Jesse, F., & Riebel, K. (2012). Social facilitation of male song by male
and female conspecifics in the zebra finch, Taeniopygia guttata. Behavioural
Processes. Elsevier. https://doi.org/10.1016/j.beproc.2012.09.006
chicago: Jesse, Fabienne, and Katharina Riebel. “Social Facilitation of Male Song
by Male and Female Conspecifics in the Zebra Finch, Taeniopygia Guttata.” Behavioural
Processes. Elsevier, 2012. https://doi.org/10.1016/j.beproc.2012.09.006.
ieee: F. Jesse and K. Riebel, “Social facilitation of male song by male and female
conspecifics in the zebra finch, Taeniopygia guttata,” Behavioural Processes,
vol. 91, no. 3. Elsevier, pp. 262–266, 2012.
ista: Jesse F, Riebel K. 2012. Social facilitation of male song by male and female
conspecifics in the zebra finch, Taeniopygia guttata. Behavioural Processes. 91(3),
262–266.
mla: Jesse, Fabienne, and Katharina Riebel. “Social Facilitation of Male Song by
Male and Female Conspecifics in the Zebra Finch, Taeniopygia Guttata.” Behavioural
Processes, vol. 91, no. 3, Elsevier, 2012, pp. 262–66, doi:10.1016/j.beproc.2012.09.006.
short: F. Jesse, K. Riebel, Behavioural Processes 91 (2012) 262–266.
date_created: 2018-12-11T12:00:35Z
date_published: 2012-11-01T00:00:00Z
date_updated: 2021-01-12T07:40:06Z
day: '01'
department:
- _id: JoBo
doi: 10.1016/j.beproc.2012.09.006
intvolume: ' 91'
issue: '3'
language:
- iso: eng
month: '11'
oa_version: None
page: 262 - 266
publication: Behavioural Processes
publication_status: published
publisher: Elsevier
publist_id: '3756'
quality_controlled: '1'
status: public
title: Social facilitation of male song by male and female conspecifics in the zebra
finch, Taeniopygia guttata
type: journal_article
user_id: 3E5EF7F0-F248-11E8-B48F-1D18A9856A87
volume: 91
year: '2012'
...
---
_id: '2974'
abstract:
- lang: eng
text: "We construct a perfectly binding string commitment scheme whose security
is based on the learning parity with noise (LPN) assumption, or equivalently,
the hardness of decoding random linear codes. Our scheme not only allows for a
simple and efficient zero-knowledge proof of knowledge for committed values (essentially
a Σ-protocol), but also for such proofs showing any kind of relation amongst committed
values, i.e. proving that messages m_0,...,m_u, are such that m_0=C(m_1,...,m_u)
for any circuit C.\r\n\r\nTo get soundness which is exponentially small in a security
parameter t, and when the zero-knowledge property relies on the LPN problem with
secrets of length l, our 3 round protocol has communication complexity O(t|C|l
log(l)) and computational complexity of O(t|C|l) bit operations. The hidden constants
are small, and the computation consists mostly of computing inner products of
bit-vectors."
acknowledgement: "We are grateful to Petros Mol for helpful discussions on the reduction
for the hardness of the xLPN problem.\r\n"
alternative_title:
- LNCS
author:
- first_name: Abhishek
full_name: Jain, Abhishek
last_name: Jain
- first_name: Stephan
full_name: Krenn, Stephan
id: 329FCCF0-F248-11E8-B48F-1D18A9856A87
last_name: Krenn
orcid: 0000-0003-2835-9093
- first_name: Krzysztof Z
full_name: Pietrzak, Krzysztof Z
id: 3E04A7AA-F248-11E8-B48F-1D18A9856A87
last_name: Pietrzak
orcid: 0000-0002-9139-1654
- first_name: Aris
full_name: Tentes, Aris
last_name: Tentes
citation:
ama: 'Jain A, Krenn S, Pietrzak KZ, Tentes A. Commitments and efficient zero knowledge
proofs from learning parity with noise. In: Wang X, Sako K, eds. Vol 7658. Springer;
2012:663-680. doi:10.1007/978-3-642-34961-4_40'
apa: 'Jain, A., Krenn, S., Pietrzak, K. Z., & Tentes, A. (2012). Commitments
and efficient zero knowledge proofs from learning parity with noise. In X. Wang
& K. Sako (Eds.) (Vol. 7658, pp. 663–680). Presented at the ASIACRYPT: Theory
and Application of Cryptology and Information Security, Beijing, China: Springer.
https://doi.org/10.1007/978-3-642-34961-4_40'
chicago: Jain, Abhishek, Stephan Krenn, Krzysztof Z Pietrzak, and Aris Tentes. “Commitments
and Efficient Zero Knowledge Proofs from Learning Parity with Noise.” edited by
Xiaoyun Wang and Kazue Sako, 7658:663–80. Springer, 2012. https://doi.org/10.1007/978-3-642-34961-4_40.
ieee: 'A. Jain, S. Krenn, K. Z. Pietrzak, and A. Tentes, “Commitments and efficient
zero knowledge proofs from learning parity with noise,” presented at the ASIACRYPT:
Theory and Application of Cryptology and Information Security, Beijing, China,
2012, vol. 7658, pp. 663–680.'
ista: 'Jain A, Krenn S, Pietrzak KZ, Tentes A. 2012. Commitments and efficient zero
knowledge proofs from learning parity with noise. ASIACRYPT: Theory and Application
of Cryptology and Information Security, LNCS, vol. 7658, 663–680.'
mla: Jain, Abhishek, et al. Commitments and Efficient Zero Knowledge Proofs from
Learning Parity with Noise. Edited by Xiaoyun Wang and Kazue Sako, vol. 7658,
Springer, 2012, pp. 663–80, doi:10.1007/978-3-642-34961-4_40.
short: A. Jain, S. Krenn, K.Z. Pietrzak, A. Tentes, in:, X. Wang, K. Sako (Eds.),
Springer, 2012, pp. 663–680.
conference:
end_date: 2012-12-06
location: Beijing, China
name: 'ASIACRYPT: Theory and Application of Cryptology and Information Security'
start_date: 2012-12-02
date_created: 2018-12-11T12:00:38Z
date_published: 2012-12-01T00:00:00Z
date_updated: 2021-01-12T07:40:11Z
day: '01'
ddc:
- '004'
- '005'
department:
- _id: KrPi
doi: 10.1007/978-3-642-34961-4_40
ec_funded: 1
editor:
- first_name: Xiaoyun
full_name: Wang, Xiaoyun
last_name: Wang
- first_name: Kazue
full_name: Sako, Kazue
last_name: Sako
file:
- access_level: open_access
checksum: ab879537385efc4cb4203e7ef0fea17b
content_type: application/pdf
creator: system
date_created: 2018-12-12T10:14:00Z
date_updated: 2020-07-14T12:45:58Z
file_id: '5048'
file_name: IST-2016-721-v1+1_513.pdf
file_size: 482570
relation: main_file
file_date_updated: 2020-07-14T12:45:58Z
has_accepted_license: '1'
intvolume: ' 7658'
language:
- iso: eng
month: '12'
oa: 1
oa_version: Submitted Version
page: 663 - 680
project:
- _id: 258C570E-B435-11E9-9278-68D0E5697425
call_identifier: FP7
grant_number: '259668'
name: Provable Security for Physical Cryptography
publication_status: published
publisher: Springer
publist_id: '3730'
pubrep_id: '721'
scopus_import: 1
status: public
title: Commitments and efficient zero knowledge proofs from learning parity with noise
tmp:
image: /images/cc_by.png
legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
short: CC BY (4.0)
type: conference
user_id: 3E5EF7F0-F248-11E8-B48F-1D18A9856A87
volume: 7658
year: '2012'
...
---
_id: '2969'
abstract:
- lang: eng
text: "The coupling between presynaptic Ca^(2+) channels and Ca^(2+) sensors of
exocytosis is a key determinant of synaptic transmission. Evoked release from
parvalbumin (PV)-expressing interneurons is triggered by nanodomain coupling of
P/Q-type Ca^(2+) channels, whereas release from cholecystokinin (CCK)-containing
interneurons is generated by microdomain coupling of N-type channels. Nanodomain
coupling has several functional advantages, including speed and efficacy of transmission.
One potential disadvantage is that stochastic\r\nopening of presynaptic Ca^(2+)
channels may trigger spontaneous transmitter release. We addressed this possibility
in rat hippocampal\r\ngranule cells, which receive converging inputs from different
inhibitory sources. Both reduction of extracellular Ca^(2+) concentration and
the unselective Ca^(2+) channel blocker Cd^(2+) reduced the frequency of miniature
IPSCs (mIPSCs) in granule cells by ~50%, suggesting that the opening of presynaptic
Ca^(2+) channels contributes to spontaneous release. Application of the selective
P/Q-type Ca^(2+) channel blocker\r\nω-agatoxin IVa had no detectable effects,
whereas both the N-type blocker ω-conotoxin GVIa and the L-type blocker nimodipine
reduced\r\nmIPSC frequency. Furthermore, both the fast Ca^(2+) chelator BAPTA-AM
and the slow chelator EGTA-AM reduced the mIPSC frequency,\r\nsuggesting that
Ca^(2+)-dependent spontaneous release is triggered by microdomain rather than
nanodomain coupling. The CB_(1) receptor\r\nagonist WIN 55212-2 also decreased
spontaneous release; this effect was occluded by prior application of ω-conotoxin
GVIa, suggesting that a major fraction of Ca^(2+)-dependent spontaneous release
was generated at the terminals of CCK-expressing interneurons. Tonic inhibition
generated by spontaneous opening of presynaptic N- and L-type Ca^(2+) channels
may be important for hippocampal information processing.\r\n"
acknowledgement: This work was supported by grants from the Deutsche Forschungsgemeinschaft
(TR 3/B10, Leibniz program, GSC-4 Spemann Graduate School) and the European Union
(European Research Council Advanced Grant).
author:
- first_name: Sarit
full_name: Goswami, Sarit
id: 3A578F32-F248-11E8-B48F-1D18A9856A87
last_name: Goswami
- first_name: Iancu
full_name: Bucurenciu, Iancu
last_name: Bucurenciu
- first_name: Peter M
full_name: Jonas, Peter M
id: 353C1B58-F248-11E8-B48F-1D18A9856A87
last_name: Jonas
orcid: 0000-0001-5001-4804
citation:
ama: Goswami S, Bucurenciu I, Jonas PM. Miniature IPSCs in hippocampal granule cells
are triggered by voltage-gated Ca^(2+) channels via microdomain coupling. Journal
of Neuroscience. 2012;32(41):14294-14304. doi:10.1523/JNEUROSCI.6104-11.2012
apa: Goswami, S., Bucurenciu, I., & Jonas, P. M. (2012). Miniature IPSCs in
hippocampal granule cells are triggered by voltage-gated Ca^(2+) channels via
microdomain coupling. Journal of Neuroscience. Society for Neuroscience.
https://doi.org/10.1523/JNEUROSCI.6104-11.2012
chicago: Goswami, Sarit, Iancu Bucurenciu, and Peter M Jonas. “Miniature IPSCs in
Hippocampal Granule Cells Are Triggered by Voltage-Gated Ca^(2+) Channels via
Microdomain Coupling.” Journal of Neuroscience. Society for Neuroscience,
2012. https://doi.org/10.1523/JNEUROSCI.6104-11.2012.
ieee: S. Goswami, I. Bucurenciu, and P. M. Jonas, “Miniature IPSCs in hippocampal
granule cells are triggered by voltage-gated Ca^(2+) channels via microdomain
coupling,” Journal of Neuroscience, vol. 32, no. 41. Society for Neuroscience,
pp. 14294–14304, 2012.
ista: Goswami S, Bucurenciu I, Jonas PM. 2012. Miniature IPSCs in hippocampal granule
cells are triggered by voltage-gated Ca^(2+) channels via microdomain coupling.
Journal of Neuroscience. 32(41), 14294–14304.
mla: Goswami, Sarit, et al. “Miniature IPSCs in Hippocampal Granule Cells Are Triggered
by Voltage-Gated Ca^(2+) Channels via Microdomain Coupling.” Journal of Neuroscience,
vol. 32, no. 41, Society for Neuroscience, 2012, pp. 14294–304, doi:10.1523/JNEUROSCI.6104-11.2012.
short: S. Goswami, I. Bucurenciu, P.M. Jonas, Journal of Neuroscience 32 (2012)
14294–14304.
date_created: 2018-12-11T12:00:36Z
date_published: 2012-10-10T00:00:00Z
date_updated: 2021-01-12T07:40:08Z
day: '10'
department:
- _id: PeJo
doi: 10.1523/JNEUROSCI.6104-11.2012
external_id:
pmid:
- '23055500'
intvolume: ' 32'
issue: '41'
language:
- iso: eng
main_file_link:
- open_access: '1'
url: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3632771/
month: '10'
oa: 1
oa_version: Submitted Version
page: 14294 - 14304
pmid: 1
project:
- _id: 25BDE9A4-B435-11E9-9278-68D0E5697425
grant_number: SFB-TR3-TP10B
name: Glutamaterge synaptische Übertragung und Plastizität in hippocampalen Mikroschaltkreisen
publication: Journal of Neuroscience
publication_status: published
publisher: Society for Neuroscience
publist_id: '3744'
quality_controlled: '1'
scopus_import: 1
status: public
title: Miniature IPSCs in hippocampal granule cells are triggered by voltage-gated
Ca^(2+) channels via microdomain coupling
type: journal_article
user_id: 3E5EF7F0-F248-11E8-B48F-1D18A9856A87
volume: 32
year: '2012'
...