--- _id: '1299' abstract: - lang: eng text: Recent experiments have shown that motion detection in Drosophila starts with splitting the visual input into two parallel channels encoding brightness increments (ON) or decrements (OFF). This suggests the existence of either two (ON-ON, OFF-OFF) or four (for all pairwise interactions) separate motion detectors. To decide between these possibilities, we stimulated flies using sequences of ON and OFF brightness pulses while recording from motion-sensitive tangential cells. We found direction-selective responses to sequences of same sign (ON-ON, OFF-OFF), but not of opposite sign (ON-OFF, OFF-ON), refuting the existence of four separate detectors. Based on further measurements, we propose a model that reproduces a variety of additional experimental data sets, including ones that were previously interpreted as support for four separate detectors. Our experiments and the derived model mark an important step in guiding further dissection of the fly motion detection circuit. author: - first_name: Hubert full_name: Eichner, Hubert last_name: Eichner - first_name: Maximilian A full_name: Maximilian Jösch id: 2BD278E6-F248-11E8-B48F-1D18A9856A87 last_name: Jösch orcid: 0000-0002-3937-1330 - first_name: Bettina full_name: Schnell, Bettina last_name: Schnell - first_name: Dierk full_name: Reiff, Dierk F last_name: Reiff - first_name: Alexander full_name: Borst, Alexander last_name: Borst citation: ama: Eichner H, Jösch MA, Schnell B, Reiff D, Borst A. Internal structure of the fly elementary motion detector. Neuron. 2011;70(6):1155-1164. doi:10.1016/j.neuron.2011.03.028 apa: Eichner, H., Jösch, M. A., Schnell, B., Reiff, D., & Borst, A. (2011). Internal structure of the fly elementary motion detector. Neuron. Elsevier. https://doi.org/10.1016/j.neuron.2011.03.028 chicago: Eichner, Hubert, Maximilian A Jösch, Bettina Schnell, Dierk Reiff, and Alexander Borst. “Internal Structure of the Fly Elementary Motion Detector.” Neuron. Elsevier, 2011. https://doi.org/10.1016/j.neuron.2011.03.028. ieee: H. Eichner, M. A. Jösch, B. Schnell, D. Reiff, and A. Borst, “Internal structure of the fly elementary motion detector,” Neuron, vol. 70, no. 6. Elsevier, pp. 1155–1164, 2011. ista: Eichner H, Jösch MA, Schnell B, Reiff D, Borst A. 2011. Internal structure of the fly elementary motion detector. Neuron. 70(6), 1155–1164. mla: Eichner, Hubert, et al. “Internal Structure of the Fly Elementary Motion Detector.” Neuron, vol. 70, no. 6, Elsevier, 2011, pp. 1155–64, doi:10.1016/j.neuron.2011.03.028. short: H. Eichner, M.A. Jösch, B. Schnell, D. Reiff, A. Borst, Neuron 70 (2011) 1155–1164. date_created: 2018-12-11T11:51:14Z date_published: 2011-06-23T00:00:00Z date_updated: 2021-01-12T06:49:43Z day: '23' doi: 10.1016/j.neuron.2011.03.028 extern: 1 intvolume: ' 70' issue: '6' month: '06' page: 1155 - 1164 publication: Neuron publication_status: published publisher: Elsevier publist_id: '5969' quality_controlled: 0 status: public title: Internal structure of the fly elementary motion detector type: journal_article volume: 70 year: '2011' ... --- _id: '1467' abstract: - lang: eng text: We propose a general conjecture for the mixed Hodge polynomial of the generic character varieties of representations of the fundamental group of a Riemann surface of genus g to GLn(C) with fixed generic semisimple conjugacy classes at k punctures. This conjecture generalizes the Cauchy identity for Macdonald polynomials and is a common generalization of two formulas that we prove in this paper. The first is a formula for the E-polynomial of these character varieties which we obtain using the character table of GLn(Fq). We use this formula to compute the Euler characteristic of character varieties. The second formula gives the Poincaré polynomial of certain associated quiver varieties which we obtain using the character table of gln(Fq). In the last main result we prove that the Poincaré polynomials of the quiver varieties equal certain multiplicities in the tensor product of irreducible characters of GLn(Fq). As a consequence we find a curious connection between Kac-Moody algebras associated with comet-shaped, and typically wild, quivers and the representation theory of GLn(Fq). acknowledgement: |- Hausel’s work was supported by National Science Foundation grants DMS-0305505 and DMS-0604775, by an Alfred Sloan Fellowship, and by a Royal Society University Research Fellowship. Letellier’s work supported by Agence Nationale de la Recherche grant ANR-09-JCJC-0102-01. Rodriguez-Villegas’s work supported by National Science Foundation grant DMS-0200605, by an FRA from the University of Texas at Austin, by EPSRC grant EP/G027110/1, by visiting fellowships at All Souls and Wadham Colleges in Oxford, and by a Research Scholarship from the Clay Mathematical Institute. author: - first_name: Tamas full_name: Tamas Hausel id: 4A0666D8-F248-11E8-B48F-1D18A9856A87 last_name: Hausel - first_name: Emmanuel full_name: Letellier, Emmanuel last_name: Letellier - first_name: Fernando full_name: Rodríguez Villegas, Fernando last_name: Rodríguez Villegas citation: ama: Hausel T, Letellier E, Rodríguez Villegas F. Arithmetic harmonic analysis on character and quiver varieties. Duke Mathematical Journal. 2011;160(2):323-400. doi:10.1215/00127094-1444258 apa: Hausel, T., Letellier, E., & Rodríguez Villegas, F. (2011). Arithmetic harmonic analysis on character and quiver varieties. Duke Mathematical Journal. Duke University Press. https://doi.org/10.1215/00127094-1444258 chicago: Hausel, Tamás, Emmanuel Letellier, and Fernando Rodríguez Villegas. “Arithmetic Harmonic Analysis on Character and Quiver Varieties.” Duke Mathematical Journal. Duke University Press, 2011. https://doi.org/10.1215/00127094-1444258. ieee: T. Hausel, E. Letellier, and F. Rodríguez Villegas, “Arithmetic harmonic analysis on character and quiver varieties,” Duke Mathematical Journal, vol. 160, no. 2. Duke University Press, pp. 323–400, 2011. ista: Hausel T, Letellier E, Rodríguez Villegas F. 2011. Arithmetic harmonic analysis on character and quiver varieties. Duke Mathematical Journal. 160(2), 323–400. mla: Hausel, Tamás, et al. “Arithmetic Harmonic Analysis on Character and Quiver Varieties.” Duke Mathematical Journal, vol. 160, no. 2, Duke University Press, 2011, pp. 323–400, doi:10.1215/00127094-1444258. short: T. Hausel, E. Letellier, F. Rodríguez Villegas, Duke Mathematical Journal 160 (2011) 323–400. date_created: 2018-12-11T11:52:11Z date_published: 2011-01-01T00:00:00Z date_updated: 2021-01-12T06:50:56Z day: '01' doi: 10.1215/00127094-1444258 extern: 1 intvolume: ' 160' issue: '2' main_file_link: - open_access: '1' url: http://arxiv.org/abs/0810.2076 month: '01' oa: 1 page: 323 - 400 publication: Duke Mathematical Journal publication_status: published publisher: Duke University Press publist_id: '5728' quality_controlled: 0 status: public title: Arithmetic harmonic analysis on character and quiver varieties type: journal_article volume: 160 year: '2011' ... --- _id: '1723' abstract: - lang: eng text: The emergence of differences in the arrangement of cells is the first step towards the establishment of many organs. Understanding this process is limited by the lack of systematic characterization of epithelial organisation. Here we apply network theory at the scale of individual cells to uncover patterns in cell-to-cell contacts that govern epithelial organisation. We provide an objective characterisation of epithelia using network representation, where cells are nodes and cell contacts are links. The features of individual cells, together with attributes of the cellular network, produce a defining signature that distinguishes epithelia from different organs, species, developmental stages and genetic conditions. The approach permits characterization, quantification and classification of normal and perturbed epithelia, and establishes a framework for understanding molecular mechanisms that underpin the architecture of complex tissues. acknowledgement: We acknowledge the MRC for funding, M.M.B. acknowledges Darwin College, EMBO YIP and Schlumberger Ltd for support. L.M.E. is funded by the Marie Curie and the EMBO fellowships. L.d.F.C. is grateful to FAPESP (05/00587-5) and CNPq (301303/06-1) for financial support. Part of this work was performed during a Visiting Scholarship to L.d.F.C. from St Catharine's College, University of Cambridge. J.B. is supported by the MRC (UK) and A.K. by a FEBS fellowship author: - first_name: Luis full_name: Escudero, Luis M last_name: Escudero - first_name: Luciano full_name: Costa, Luciano last_name: Costa - first_name: Anna full_name: Anna Kicheva id: 3959A2A0-F248-11E8-B48F-1D18A9856A87 last_name: Kicheva orcid: 0000-0003-4509-4998 - first_name: James full_name: Briscoe, James last_name: Briscoe - first_name: Matthew full_name: Freeman, Matthew last_name: Freeman - first_name: Madan full_name: Babu, Madan M last_name: Babu citation: ama: Escudero L, Costa L, Kicheva A, Briscoe J, Freeman M, Babu M. Epithelial organisation revealed by a network of cellular contacts. Nature Communications. 2011;2(1). doi:10.1038/ncomms1536 apa: Escudero, L., Costa, L., Kicheva, A., Briscoe, J., Freeman, M., & Babu, M. (2011). Epithelial organisation revealed by a network of cellular contacts. Nature Communications. Nature Publishing Group. https://doi.org/10.1038/ncomms1536 chicago: Escudero, Luis, Luciano Costa, Anna Kicheva, James Briscoe, Matthew Freeman, and Madan Babu. “Epithelial Organisation Revealed by a Network of Cellular Contacts.” Nature Communications. Nature Publishing Group, 2011. https://doi.org/10.1038/ncomms1536. ieee: L. Escudero, L. Costa, A. Kicheva, J. Briscoe, M. Freeman, and M. Babu, “Epithelial organisation revealed by a network of cellular contacts,” Nature Communications, vol. 2, no. 1. Nature Publishing Group, 2011. ista: Escudero L, Costa L, Kicheva A, Briscoe J, Freeman M, Babu M. 2011. Epithelial organisation revealed by a network of cellular contacts. Nature Communications. 2(1). mla: Escudero, Luis, et al. “Epithelial Organisation Revealed by a Network of Cellular Contacts.” Nature Communications, vol. 2, no. 1, Nature Publishing Group, 2011, doi:10.1038/ncomms1536. short: L. Escudero, L. Costa, A. Kicheva, J. Briscoe, M. Freeman, M. Babu, Nature Communications 2 (2011). date_created: 2018-12-11T11:53:40Z date_published: 2011-01-01T00:00:00Z date_updated: 2021-01-12T06:52:46Z day: '01' doi: 10.1038/ncomms1536 extern: 1 intvolume: ' 2' issue: '1' month: '01' publication: Nature Communications publication_status: published publisher: Nature Publishing Group publist_id: '5405' quality_controlled: 0 status: public title: Epithelial organisation revealed by a network of cellular contacts type: journal_article volume: 2 year: '2011' ... --- _id: '1724' abstract: - lang: eng text: Morphogens, such as Decapentaplegic (Dpp) in the fly imaginal discs, form graded concentration profiles that control patterning and growth of developing organs. In the imaginal discs, proliferative growth is homogeneous in space, posing the conundrum of how morphogen concentration gradients could control position-independent growth. To understand the mechanism of proliferation control by the Dpp gradient, we quantified Dpp concentration and signaling levels during wing disc growth. Both Dpp concentration and signaling gradients scale with tissue size during development. On average, cells divide when Dpp signaling levels have increased by 50%. Our observations are consistent with a growth control mechanism based on temporal changes of cellular morphogen signaling levels. For a scaling gradient, this mechanism generates position-independent growth rates. acknowledgement: P.M., T.B., and F.J. were supported by the Max-Planck-Gesellschaft. O.W., A.K., C.S., and M.G.-G. were supported by Geneva University and by European Research Council advanced investigator grant (SARA), SystemsX (LipidX), Swiss National Science Foundation (SNF), National Centre of Competence in Research (NCCR) chemical biology and Frontiers in Genetics and R'equip grants author: - first_name: Ortrud full_name: Wartlick, Ortrud last_name: Wartlick - first_name: Peer full_name: Mumcu, Peer last_name: Mumcu - first_name: Anna full_name: Anna Kicheva id: 3959A2A0-F248-11E8-B48F-1D18A9856A87 last_name: Kicheva orcid: 0000-0003-4509-4998 - first_name: Thomas full_name: Bittig, Thomas last_name: Bittig - first_name: Carole full_name: Seum, Carole last_name: Seum - first_name: Frank full_name: Jülicher, Frank last_name: Jülicher - first_name: Marcos full_name: González-Gaitán, Marcos A last_name: González Gaitán citation: ama: Wartlick O, Mumcu P, Kicheva A, et al. Dynamics of Dpp signaling and proliferation control. Science. 2011;331(6021):1154-1159. doi:10.1126/science.1200037 apa: Wartlick, O., Mumcu, P., Kicheva, A., Bittig, T., Seum, C., Jülicher, F., & González Gaitán, M. (2011). Dynamics of Dpp signaling and proliferation control. Science. American Association for the Advancement of Science. https://doi.org/10.1126/science.1200037 chicago: Wartlick, Ortrud, Peer Mumcu, Anna Kicheva, Thomas Bittig, Carole Seum, Frank Jülicher, and Marcos González Gaitán. “Dynamics of Dpp Signaling and Proliferation Control.” Science. American Association for the Advancement of Science, 2011. https://doi.org/10.1126/science.1200037. ieee: O. Wartlick et al., “Dynamics of Dpp signaling and proliferation control,” Science, vol. 331, no. 6021. American Association for the Advancement of Science, pp. 1154–1159, 2011. ista: Wartlick O, Mumcu P, Kicheva A, Bittig T, Seum C, Jülicher F, González Gaitán M. 2011. Dynamics of Dpp signaling and proliferation control. Science. 331(6021), 1154–1159. mla: Wartlick, Ortrud, et al. “Dynamics of Dpp Signaling and Proliferation Control.” Science, vol. 331, no. 6021, American Association for the Advancement of Science, 2011, pp. 1154–59, doi:10.1126/science.1200037. short: O. Wartlick, P. Mumcu, A. Kicheva, T. Bittig, C. Seum, F. Jülicher, M. González Gaitán, Science 331 (2011) 1154–1159. date_created: 2018-12-11T11:53:40Z date_published: 2011-03-04T00:00:00Z date_updated: 2021-01-12T06:52:46Z day: '04' doi: 10.1126/science.1200037 extern: 1 intvolume: ' 331' issue: '6021' month: '03' page: 1154 - 1159 publication: Science publication_status: published publisher: American Association for the Advancement of Science publist_id: '5406' quality_controlled: 0 status: public title: Dynamics of Dpp signaling and proliferation control type: journal_article volume: 331 year: '2011' ... --- _id: '1754' abstract: - lang: eng text: 'We report on a technique enabling electrical control of the contact silicidation process in silicon nanowire devices. Undoped silicon nanowires were contacted by pairs of nickel electrodes and each contact was selectively silicided by means of the Joule effect. By a realtime monitoring of the nanowire electrical resistance during the contact silicidation process we were able to fabricate nickel-silicide/silicon/nickel- silicide devices with controlled silicon channel length down to 8 nm. ' acknowledgement: This work was supported by the Agence Nationale de la Recherche (ANR) through the ACCESS and COHESION projects and by the European Commission through the Chemtronics program MEST-CT-2005-020513 author: - first_name: Massimo full_name: Mongillo, Massimo last_name: Mongillo - first_name: Panayotis full_name: Spathis, Panayotis last_name: Spathis - first_name: Georgios full_name: Katsaros, Georgios id: 38DB5788-F248-11E8-B48F-1D18A9856A87 last_name: Katsaros - first_name: Pascal full_name: Gentile, Pascal last_name: Gentile - first_name: Marc full_name: Sanquer, Marc last_name: Sanquer - first_name: Silvano full_name: De Franceschi, Silvano last_name: De Franceschi citation: ama: Mongillo M, Spathis P, Katsaros G, Gentile P, Sanquer M, De Franceschi S. Joule-assisted silicidation for short-channel silicon nanowire devices. ACS Nano. 2011;5(9):7117-7123. doi:10.1021/nn202524j apa: Mongillo, M., Spathis, P., Katsaros, G., Gentile, P., Sanquer, M., & De Franceschi, S. (2011). Joule-assisted silicidation for short-channel silicon nanowire devices. ACS Nano. American Chemical Society. https://doi.org/10.1021/nn202524j chicago: Mongillo, Massimo, Panayotis Spathis, Georgios Katsaros, Pascal Gentile, Marc Sanquer, and Silvano De Franceschi. “Joule-Assisted Silicidation for Short-Channel Silicon Nanowire Devices.” ACS Nano. American Chemical Society, 2011. https://doi.org/10.1021/nn202524j. ieee: M. Mongillo, P. Spathis, G. Katsaros, P. Gentile, M. Sanquer, and S. De Franceschi, “Joule-assisted silicidation for short-channel silicon nanowire devices,” ACS Nano, vol. 5, no. 9. American Chemical Society, pp. 7117–7123, 2011. ista: Mongillo M, Spathis P, Katsaros G, Gentile P, Sanquer M, De Franceschi S. 2011. Joule-assisted silicidation for short-channel silicon nanowire devices. ACS Nano. 5(9), 7117–7123. mla: Mongillo, Massimo, et al. “Joule-Assisted Silicidation for Short-Channel Silicon Nanowire Devices.” ACS Nano, vol. 5, no. 9, American Chemical Society, 2011, pp. 7117–23, doi:10.1021/nn202524j. short: M. Mongillo, P. Spathis, G. Katsaros, P. Gentile, M. Sanquer, S. De Franceschi, ACS Nano 5 (2011) 7117–7123. date_created: 2018-12-11T11:53:50Z date_published: 2011-09-27T00:00:00Z date_updated: 2021-01-12T06:52:59Z day: '27' doi: 10.1021/nn202524j extern: '1' external_id: arxiv: - '1110.5668' intvolume: ' 5' issue: '9' language: - iso: eng main_file_link: - open_access: '1' url: http://arxiv.org/abs/1110.5668 month: '09' oa: 1 oa_version: Preprint page: 7117 - 7123 publication: ACS Nano publication_status: published publisher: American Chemical Society publist_id: '5370' quality_controlled: '1' status: public title: Joule-assisted silicidation for short-channel silicon nanowire devices type: journal_article user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87 volume: 5 year: '2011' ... --- _id: '1755' abstract: - lang: eng text: Spin-selective tunneling of holes in SiGe nanocrystals contacted by normal-metal leads is reported. The spin selectivity arises from an interplay of the orbital effect of the magnetic field with the strong spin-orbit interaction present in the valence band of the semiconductor. We demonstrate both experimentally and theoretically that spin-selective tunneling in semiconductor nanostructures can be achieved without the use of ferromagnetic contacts. The reported effect, which relies on mixing the light and heavy holes, should be observable in a broad class of quantum-dot systems formed in semiconductors with a degenerate valence band. acknowledgement: The work was supported by the Agence Nationale de la Recherche (through the ACCESS and COHESION projects), U.S. DOE Contract No. DE-FG02-08ER46482 (Yale), and the Nanosciences Foundation at Grenoble, France. G. K. acknowledges support from the Deutsche Forschungsgemeinschaft author: - first_name: Georgios full_name: Georgios Katsaros id: 38DB5788-F248-11E8-B48F-1D18A9856A87 last_name: Katsaros - first_name: Vitaly full_name: Golovach, Vitaly N last_name: Golovach - first_name: Panayotis full_name: Spathis, Panayotis N last_name: Spathis - first_name: Natalia full_name: Ares, Natalia last_name: Ares - first_name: Mathieu full_name: Stoffel, Mathieu last_name: Stoffel - first_name: Frank full_name: Fournel, Frank last_name: Fournel - first_name: Oliver full_name: Schmidt, Oliver G last_name: Schmidt - first_name: Leonid full_name: Glazman, Leonid I last_name: Glazman - first_name: Silvano full_name: De Franceschi, Silvano last_name: De Franceschi citation: ama: Katsaros G, Golovach V, Spathis P, et al. Observation of spin-selective tunneling in sige nanocrystals. Physical Review Letters. 2011;107(24). doi:10.1103/PhysRevLett.107.246601 apa: Katsaros, G., Golovach, V., Spathis, P., Ares, N., Stoffel, M., Fournel, F., … De Franceschi, S. (2011). Observation of spin-selective tunneling in sige nanocrystals. Physical Review Letters. American Physical Society. https://doi.org/10.1103/PhysRevLett.107.246601 chicago: Katsaros, Georgios, Vitaly Golovach, Panayotis Spathis, Natalia Ares, Mathieu Stoffel, Frank Fournel, Oliver Schmidt, Leonid Glazman, and Silvano De Franceschi. “Observation of Spin-Selective Tunneling in Sige Nanocrystals.” Physical Review Letters. American Physical Society, 2011. https://doi.org/10.1103/PhysRevLett.107.246601. ieee: G. Katsaros et al., “Observation of spin-selective tunneling in sige nanocrystals,” Physical Review Letters, vol. 107, no. 24. American Physical Society, 2011. ista: Katsaros G, Golovach V, Spathis P, Ares N, Stoffel M, Fournel F, Schmidt O, Glazman L, De Franceschi S. 2011. Observation of spin-selective tunneling in sige nanocrystals. Physical Review Letters. 107(24). mla: Katsaros, Georgios, et al. “Observation of Spin-Selective Tunneling in Sige Nanocrystals.” Physical Review Letters, vol. 107, no. 24, American Physical Society, 2011, doi:10.1103/PhysRevLett.107.246601. short: G. Katsaros, V. Golovach, P. Spathis, N. Ares, M. Stoffel, F. Fournel, O. Schmidt, L. Glazman, S. De Franceschi, Physical Review Letters 107 (2011). date_created: 2018-12-11T11:53:50Z date_published: 2011-12-07T00:00:00Z date_updated: 2021-01-12T06:53:00Z day: '07' doi: 10.1103/PhysRevLett.107.246601 extern: 1 intvolume: ' 107' issue: '24' main_file_link: - open_access: '1' url: http://arxiv.org/abs/1107.3919 month: '12' oa: 1 publication: Physical Review Letters publication_status: published publisher: American Physical Society publist_id: '5369' quality_controlled: 0 status: public title: Observation of spin-selective tunneling in sige nanocrystals type: journal_article volume: 107 year: '2011' ... --- _id: '1776' abstract: - lang: eng text: Superconducting circuits have been successfully established as systems to prepare and investigate microwave light fields at the quantum level. In contrast to optical experiments where light is detected using photon counters, microwaves are usually measured with well developed linear amplifiers. This makes measurements of correlation functions - one of the important tools in optics - harder to achieve because they traditionally rely on photon counters and beam splitters. Here, we demonstrate a system where we can prepare on demand single microwave photons in a cavity and detect them at the two outputs of the cavity using linear amplifiers. Together with efficient data processing, this allows us to measure different observables of the cavity photons, including the first-order correlation function. Using these techniques we demonstrate cooling of a thermal background field in the cavity. acknowledgement: Australian National University,Aust. Res. Counc. Cent. Excellence Quantum-Atom Opt.,Griffith University,Ian Potter Foundation,International Union of Pure and Applied Physics alternative_title: - 'Journal of Physics: Conference Series' author: - first_name: Deniz full_name: Bozyigit, Deniz last_name: Bozyigit - first_name: C full_name: Lang, C last_name: Lang - first_name: L. full_name: Steffen, L. Kraig last_name: Steffen - first_name: Johannes M full_name: Johannes Fink id: 4B591CBA-F248-11E8-B48F-1D18A9856A87 last_name: Fink orcid: 0000-0001-8112-028X - first_name: Christopher full_name: Eichler, Christopher last_name: Eichler - first_name: Matthias full_name: Baur, Matthias P last_name: Baur - first_name: R full_name: Bianchetti, R last_name: Bianchetti - first_name: Peter full_name: Leek, Peter J last_name: Leek - first_name: Stefan full_name: Filipp, Stefan last_name: Filipp - first_name: Andreas full_name: Wallraff, Andreas last_name: Wallraff - first_name: Marcus full_name: Da Silva, Marcus P last_name: Da Silva - first_name: Alexandre full_name: Blais, Alexandre last_name: Blais citation: ama: 'Bozyigit D, Lang C, Steffen L, et al. Correlation measurements of individual microwave photons emitted from a symmetric cavity. In: Vol 264. IOP Publishing Ltd.; 2011. doi:10.1088/1742-6596/264/1/012024' apa: Bozyigit, D., Lang, C., Steffen, L., Fink, J. M., Eichler, C., Baur, M., … Blais, A. (2011). Correlation measurements of individual microwave photons emitted from a symmetric cavity (Vol. 264). Presented at the International Conference on Atomic Physics, IOP Publishing Ltd. https://doi.org/10.1088/1742-6596/264/1/012024 chicago: Bozyigit, Deniz, C Lang, L. Steffen, Johannes M Fink, Christopher Eichler, Matthias Baur, R Bianchetti, et al. “Correlation Measurements of Individual Microwave Photons Emitted from a Symmetric Cavity,” Vol. 264. IOP Publishing Ltd., 2011. https://doi.org/10.1088/1742-6596/264/1/012024. ieee: D. Bozyigit et al., “Correlation measurements of individual microwave photons emitted from a symmetric cavity,” presented at the International Conference on Atomic Physics, 2011, vol. 264, no. 1. ista: 'Bozyigit D, Lang C, Steffen L, Fink JM, Eichler C, Baur M, Bianchetti R, Leek P, Filipp S, Wallraff A, Da Silva M, Blais A. 2011. Correlation measurements of individual microwave photons emitted from a symmetric cavity. International Conference on Atomic Physics, Journal of Physics: Conference Series, vol. 264.' mla: Bozyigit, Deniz, et al. Correlation Measurements of Individual Microwave Photons Emitted from a Symmetric Cavity. Vol. 264, no. 1, IOP Publishing Ltd., 2011, doi:10.1088/1742-6596/264/1/012024. short: D. Bozyigit, C. Lang, L. Steffen, J.M. Fink, C. Eichler, M. Baur, R. Bianchetti, P. Leek, S. Filipp, A. Wallraff, M. Da Silva, A. Blais, in:, IOP Publishing Ltd., 2011. conference: name: International Conference on Atomic Physics date_created: 2018-12-11T11:53:57Z date_published: 2011-01-01T00:00:00Z date_updated: 2019-04-26T07:22:05Z day: '01' doi: 10.1088/1742-6596/264/1/012024 extern: 1 intvolume: ' 264' issue: '1' month: '01' publication_status: published publisher: IOP Publishing Ltd. publist_id: '5339' quality_controlled: 0 status: public title: Correlation measurements of individual microwave photons emitted from a symmetric cavity type: conference volume: 264 year: '2011' ... --- _id: '1777' abstract: - lang: eng text: A wide range of experiments studying microwave photons localized in superconducting cavities have made important contributions to our understanding of the quantum properties of radiation. Propagating microwave photons, however, have so far been studied much less intensely. Here we present measurements in which we reconstruct the quantum state of itinerant single photon Fock states and their superposition with the vacuum by analyzing moments of the measured amplitude distribution up to fourth order. Using linear amplifiers and quadrature amplitude detectors, we have developed efficient methods to separate the detected single photon signal from the noise added by the amplifier. From our measurement data we have also reconstructed the corresponding Wigner function. acknowledgement: This work was supported by the European Research Council (ERC) through a Starting Grant and by ETHZ article_processing_charge: No author: - first_name: Christopher full_name: Eichler, Christopher last_name: Eichler - first_name: Deniz full_name: Bozyigit, Deniz last_name: Bozyigit - first_name: C full_name: Lang, C last_name: Lang - first_name: L. full_name: Steffen, L. last_name: Steffen - first_name: Johannes M full_name: Fink, Johannes M id: 4B591CBA-F248-11E8-B48F-1D18A9856A87 last_name: Fink orcid: 0000-0001-8112-028X - first_name: Andreas full_name: Wallraff, Andreas last_name: Wallraff citation: ama: Eichler C, Bozyigit D, Lang C, Steffen L, Fink JM, Wallraff A. Experimental state tomography of itinerant single microwave photons. Physical Review Letters. 2011;106(22). doi:10.1103/PhysRevLett.106.220503 apa: Eichler, C., Bozyigit, D., Lang, C., Steffen, L., Fink, J. M., & Wallraff, A. (2011). Experimental state tomography of itinerant single microwave photons. Physical Review Letters. American Physical Society. https://doi.org/10.1103/PhysRevLett.106.220503 chicago: Eichler, Christopher, Deniz Bozyigit, C Lang, L. Steffen, Johannes M Fink, and Andreas Wallraff. “Experimental State Tomography of Itinerant Single Microwave Photons.” Physical Review Letters. American Physical Society, 2011. https://doi.org/10.1103/PhysRevLett.106.220503. ieee: C. Eichler, D. Bozyigit, C. Lang, L. Steffen, J. M. Fink, and A. Wallraff, “Experimental state tomography of itinerant single microwave photons,” Physical Review Letters, vol. 106, no. 22. American Physical Society, 2011. ista: Eichler C, Bozyigit D, Lang C, Steffen L, Fink JM, Wallraff A. 2011. Experimental state tomography of itinerant single microwave photons. Physical Review Letters. 106(22). mla: Eichler, Christopher, et al. “Experimental State Tomography of Itinerant Single Microwave Photons.” Physical Review Letters, vol. 106, no. 22, American Physical Society, 2011, doi:10.1103/PhysRevLett.106.220503. short: C. Eichler, D. Bozyigit, C. Lang, L. Steffen, J.M. Fink, A. Wallraff, Physical Review Letters 106 (2011). date_created: 2018-12-11T11:53:57Z date_published: 2011-06-01T00:00:00Z date_updated: 2021-11-16T07:57:13Z day: '01' doi: 10.1103/PhysRevLett.106.220503 extern: '1' intvolume: ' 106' issue: '22' language: - iso: eng main_file_link: - open_access: '1' url: http://arxiv.org/abs/1011.6668 month: '06' oa: 1 oa_version: None publication: Physical Review Letters publication_status: published publisher: American Physical Society publist_id: '5338' related_material: link: - relation: erratum url: https://doi.org/10.1103/PhysRevLett.106.249901 status: public title: Experimental state tomography of itinerant single microwave photons type: journal_article user_id: 8b945eb4-e2f2-11eb-945a-df72226e66a9 volume: 106 year: '2011' ... --- _id: '1778' abstract: - lang: eng text: Creating a train of single photons and monitoring its propagation and interaction is challenging in most physical systems, as photons generally interact very weakly with other systems. However, when confining microwave frequency photons in a transmission line resonator, effective photon-photon interactions can be mediated by qubits embedded in the resonator. Here, we observe the phenomenon of photon blockade through second-order correlation function measurements. The experiments clearly demonstrate antibunching in a continuously pumped source of single microwave photons measured by using microwave beam splitters, linear amplifiers, and quadrature amplitude detectors. We also investigate resonance fluorescence and Rayleigh scattering in Mollow-triplet-like spectra. acknowledgement: This work was supported by the European Research Council (ERC) through a Starting Grant and by ETHZ. M. P. d. S. was supported by NSERC. A. B. was supported by NSERC, CIFAR, and the Alfred P. Sloan Foundation author: - first_name: C full_name: Lang, C last_name: Lang - first_name: Deniz full_name: Bozyigit, Deniz last_name: Bozyigit - first_name: Christopher full_name: Eichler, Christopher last_name: Eichler - first_name: L. full_name: Steffen, L. Kraig last_name: Steffen - first_name: Johannes M full_name: Johannes Fink id: 4B591CBA-F248-11E8-B48F-1D18A9856A87 last_name: Fink orcid: 0000-0001-8112-028X - first_name: Abdufarrukh full_name: Abdumalikov, Abdufarrukh A last_name: Abdumalikov - first_name: Matthias full_name: Baur, Matthias P last_name: Baur - first_name: Stefan full_name: Filipp, Stefan last_name: Filipp - first_name: Marcus full_name: Da Silva, Marcus P last_name: Da Silva - first_name: Alexandre full_name: Blais, Alexandre last_name: Blais - first_name: Andreas full_name: Wallraff, Andreas last_name: Wallraff citation: ama: Lang C, Bozyigit D, Eichler C, et al. Observation of resonant photon blockade at microwave frequencies using correlation function measurements. Physical Review Letters. 2011;106(24). doi:10.1103/PhysRevLett.106.243601 apa: Lang, C., Bozyigit, D., Eichler, C., Steffen, L., Fink, J. M., Abdumalikov, A., … Wallraff, A. (2011). Observation of resonant photon blockade at microwave frequencies using correlation function measurements. Physical Review Letters. American Physical Society. https://doi.org/10.1103/PhysRevLett.106.243601 chicago: Lang, C, Deniz Bozyigit, Christopher Eichler, L. Steffen, Johannes M Fink, Abdufarrukh Abdumalikov, Matthias Baur, et al. “Observation of Resonant Photon Blockade at Microwave Frequencies Using Correlation Function Measurements.” Physical Review Letters. American Physical Society, 2011. https://doi.org/10.1103/PhysRevLett.106.243601. ieee: C. Lang et al., “Observation of resonant photon blockade at microwave frequencies using correlation function measurements,” Physical Review Letters, vol. 106, no. 24. American Physical Society, 2011. ista: Lang C, Bozyigit D, Eichler C, Steffen L, Fink JM, Abdumalikov A, Baur M, Filipp S, Da Silva M, Blais A, Wallraff A. 2011. Observation of resonant photon blockade at microwave frequencies using correlation function measurements. Physical Review Letters. 106(24). mla: Lang, C., et al. “Observation of Resonant Photon Blockade at Microwave Frequencies Using Correlation Function Measurements.” Physical Review Letters, vol. 106, no. 24, American Physical Society, 2011, doi:10.1103/PhysRevLett.106.243601. short: C. Lang, D. Bozyigit, C. Eichler, L. Steffen, J.M. Fink, A. Abdumalikov, M. Baur, S. Filipp, M. Da Silva, A. Blais, A. Wallraff, Physical Review Letters 106 (2011). date_created: 2018-12-11T11:53:57Z date_published: 2011-06-15T00:00:00Z date_updated: 2021-01-12T06:53:08Z day: '15' doi: 10.1103/PhysRevLett.106.243601 extern: 1 intvolume: ' 106' issue: '24' main_file_link: - open_access: '1' url: http://arxiv.org/abs/1102.0461 month: '06' oa: 1 publication: Physical Review Letters publication_status: published publisher: American Physical Society publist_id: '5336' quality_controlled: 0 status: public title: Observation of resonant photon blockade at microwave frequencies using correlation function measurements type: journal_article volume: 106 year: '2011' ... --- _id: '1775' abstract: - lang: eng text: At optical frequencies the radiation produced by a source, such as a laser, a black body or a single-photon emitter, is frequently characterized by analysing the temporal correlations of emitted photons using single-photon counters. At microwave frequencies, however, there are no efficient single-photon counters yet. Instead, well-developed linear amplifiers allow for efficient measurement of the amplitude of an electromagnetic field. Here, we demonstrate first- and second-order correlation function measurements of a pulsed microwave-frequency single-photon source integrated on the same chip with a 50/50 beam splitter followed by linear amplifiers and quadrature amplitude detectors. We clearly observe single-photon coherence in first-order and photon antibunching in second-order correlation function measurements of the propagating fields. acknowledgement: This work was supported by the European Research Council (ERC) through a Starting Grant and by ETHZ. M.P.d.S. was supported by a NSERC postdoctoral fellowship. A.B. was supported by NSERC, CIFAR and the Alfred P. Sloan Foundation author: - first_name: Deniz full_name: Bozyigit, Deniz last_name: Bozyigit - first_name: C full_name: Lang, C last_name: Lang - first_name: L. full_name: Steffen, L. Kraig last_name: Steffen - first_name: Johannes M full_name: Johannes Fink id: 4B591CBA-F248-11E8-B48F-1D18A9856A87 last_name: Fink orcid: 0000-0001-8112-028X - first_name: Christopher full_name: Eichler, Christopher last_name: Eichler - first_name: Matthias full_name: Baur, Matthias P last_name: Baur - first_name: R full_name: Bianchetti, R last_name: Bianchetti - first_name: Peter full_name: Leek, Peter J last_name: Leek - first_name: Stefan full_name: Filipp, Stefan last_name: Filipp - first_name: Marcus full_name: Da Silva, Marcus P last_name: Da Silva - first_name: Alexandre full_name: Blais, Alexandre last_name: Blais - first_name: Andreas full_name: Wallraff, Andreas last_name: Wallraff citation: ama: Bozyigit D, Lang C, Steffen L, et al. Antibunching of microwave-frequency photons observed in correlation measurements using linear detectors. Nature Physics. 2011;7(2):154-158. doi:10.1038/nphys1845 apa: Bozyigit, D., Lang, C., Steffen, L., Fink, J. M., Eichler, C., Baur, M., … Wallraff, A. (2011). Antibunching of microwave-frequency photons observed in correlation measurements using linear detectors. Nature Physics. Nature Publishing Group. https://doi.org/10.1038/nphys1845 chicago: Bozyigit, Deniz, C Lang, L. Steffen, Johannes M Fink, Christopher Eichler, Matthias Baur, R Bianchetti, et al. “Antibunching of Microwave-Frequency Photons Observed in Correlation Measurements Using Linear Detectors.” Nature Physics. Nature Publishing Group, 2011. https://doi.org/10.1038/nphys1845. ieee: D. Bozyigit et al., “Antibunching of microwave-frequency photons observed in correlation measurements using linear detectors,” Nature Physics, vol. 7, no. 2. Nature Publishing Group, pp. 154–158, 2011. ista: Bozyigit D, Lang C, Steffen L, Fink JM, Eichler C, Baur M, Bianchetti R, Leek P, Filipp S, Da Silva M, Blais A, Wallraff A. 2011. Antibunching of microwave-frequency photons observed in correlation measurements using linear detectors. Nature Physics. 7(2), 154–158. mla: Bozyigit, Deniz, et al. “Antibunching of Microwave-Frequency Photons Observed in Correlation Measurements Using Linear Detectors.” Nature Physics, vol. 7, no. 2, Nature Publishing Group, 2011, pp. 154–58, doi:10.1038/nphys1845. short: D. Bozyigit, C. Lang, L. Steffen, J.M. Fink, C. Eichler, M. Baur, R. Bianchetti, P. Leek, S. Filipp, M. Da Silva, A. Blais, A. Wallraff, Nature Physics 7 (2011) 154–158. date_created: 2018-12-11T11:53:57Z date_published: 2011-02-01T00:00:00Z date_updated: 2021-01-12T06:53:07Z day: '01' doi: 10.1038/nphys1845 extern: 1 intvolume: ' 7' issue: '2' month: '02' page: 154 - 158 publication: Nature Physics publication_status: published publisher: Nature Publishing Group publist_id: '5340' quality_controlled: 0 status: public title: Antibunching of microwave-frequency photons observed in correlation measurements using linear detectors type: journal_article volume: 7 year: '2011' ... --- _id: '1781' abstract: - lang: eng text: Microwave cavities with high quality factors enable coherent coupling of distant quantum systems. Virtual photons lead to a transverse interaction between qubits when they are nonresonant with the cavity but resonant with each other. We experimentally investigate the inverse scaling of the interqubit coupling with the detuning from a cavity mode and its proportionality to the qubit-cavity interaction strength. We demonstrate that the enhanced coupling at higher frequencies is mediated by multiple higher-harmonic cavity modes. Moreover, we observe dark states of the coupled qubit-qubit system and analyze their relation to the symmetry of the applied driving field at different frequencies. acknowledgement: This work was supported by the Swiss National Science Foundation (SNF), the Austrian Science Foundation (FWF), and ETH Zurich author: - first_name: Stefan full_name: Filipp, Stefan last_name: Filipp - first_name: M full_name: Göppl, M last_name: Göppl - first_name: Johannes M full_name: Johannes Fink id: 4B591CBA-F248-11E8-B48F-1D18A9856A87 last_name: Fink orcid: 0000-0001-8112-028X - first_name: Matthias full_name: Baur, Matthias P last_name: Baur - first_name: R full_name: Bianchetti, R last_name: Bianchetti - first_name: L. full_name: Steffen, L. Kraig last_name: Steffen - first_name: Andreas full_name: Wallraff, Andreas last_name: Wallraff citation: ama: Filipp S, Göppl M, Fink JM, et al. Multimode mediated qubit-qubit coupling and dark-state symmetries in circuit quantum electrodynamics. Physical Review A - Atomic, Molecular, and Optical Physics. 2011;83(6). doi:10.1103/PhysRevA.83.063827 apa: Filipp, S., Göppl, M., Fink, J. M., Baur, M., Bianchetti, R., Steffen, L., & Wallraff, A. (2011). Multimode mediated qubit-qubit coupling and dark-state symmetries in circuit quantum electrodynamics. Physical Review A - Atomic, Molecular, and Optical Physics. American Physical Society. https://doi.org/10.1103/PhysRevA.83.063827 chicago: Filipp, Stefan, M Göppl, Johannes M Fink, Matthias Baur, R Bianchetti, L. Steffen, and Andreas Wallraff. “Multimode Mediated Qubit-Qubit Coupling and Dark-State Symmetries in Circuit Quantum Electrodynamics.” Physical Review A - Atomic, Molecular, and Optical Physics. American Physical Society, 2011. https://doi.org/10.1103/PhysRevA.83.063827. ieee: S. Filipp et al., “Multimode mediated qubit-qubit coupling and dark-state symmetries in circuit quantum electrodynamics,” Physical Review A - Atomic, Molecular, and Optical Physics, vol. 83, no. 6. American Physical Society, 2011. ista: Filipp S, Göppl M, Fink JM, Baur M, Bianchetti R, Steffen L, Wallraff A. 2011. Multimode mediated qubit-qubit coupling and dark-state symmetries in circuit quantum electrodynamics. Physical Review A - Atomic, Molecular, and Optical Physics. 83(6). mla: Filipp, Stefan, et al. “Multimode Mediated Qubit-Qubit Coupling and Dark-State Symmetries in Circuit Quantum Electrodynamics.” Physical Review A - Atomic, Molecular, and Optical Physics, vol. 83, no. 6, American Physical Society, 2011, doi:10.1103/PhysRevA.83.063827. short: S. Filipp, M. Göppl, J.M. Fink, M. Baur, R. Bianchetti, L. Steffen, A. Wallraff, Physical Review A - Atomic, Molecular, and Optical Physics 83 (2011). date_created: 2018-12-11T11:53:58Z date_published: 2011-06-22T00:00:00Z date_updated: 2021-01-12T06:53:09Z day: '22' doi: 10.1103/PhysRevA.83.063827 extern: 1 intvolume: ' 83' issue: '6' month: '06' publication: Physical Review A - Atomic, Molecular, and Optical Physics publication_status: published publisher: American Physical Society publist_id: '5335' quality_controlled: 0 status: public title: Multimode mediated qubit-qubit coupling and dark-state symmetries in circuit quantum electrodynamics type: journal_article volume: 83 year: '2011' ... --- _id: '1780' abstract: - lang: eng text: Continuous variable entanglement between two modes of a radiation field is usually studied at optical frequencies. Here we demonstrate experiments that show the entanglement between microwave photons of different energy in a broadband squeezed beam. We use a Josephson parametric amplifier to generate the two-mode correlated state and detect all four quadrature components simultaneously in a two-channel heterodyne setup using amplitude detectors. Analyzing two-dimensional phase space histograms for all possible pairs of quadratures allows us to determine the full covariance matrix, which is in good agreement with the one expected for a two-mode squeezed state. acknowledgement: This work was supported by the European Research Council (ERC) through a Starting grant and by ETHZ. S. F. acknowledges the Austrian Science Foundation (FWF) for support author: - first_name: Christopher full_name: Eichler, Christopher last_name: Eichler - first_name: Deniz full_name: Bozyigit, Deniz last_name: Bozyigit - first_name: C full_name: Lang, C last_name: Lang - first_name: Matthias full_name: Baur, Matthias P last_name: Baur - first_name: L. full_name: Steffen, L. Kraig last_name: Steffen - first_name: Johannes M full_name: Johannes Fink id: 4B591CBA-F248-11E8-B48F-1D18A9856A87 last_name: Fink orcid: 0000-0001-8112-028X - first_name: Stefan full_name: Filipp, Stefan last_name: Filipp - first_name: Andreas full_name: Wallraff, Andreas last_name: Wallraff citation: ama: Eichler C, Bozyigit D, Lang C, et al. Observation of two-mode squeezing in the microwave frequency domain. Physical Review Letters. 2011;107(11). doi:10.1103/PhysRevLett.107.113601 apa: Eichler, C., Bozyigit, D., Lang, C., Baur, M., Steffen, L., Fink, J. M., … Wallraff, A. (2011). Observation of two-mode squeezing in the microwave frequency domain. Physical Review Letters. American Physical Society. https://doi.org/10.1103/PhysRevLett.107.113601 chicago: Eichler, Christopher, Deniz Bozyigit, C Lang, Matthias Baur, L. Steffen, Johannes M Fink, Stefan Filipp, and Andreas Wallraff. “Observation of Two-Mode Squeezing in the Microwave Frequency Domain.” Physical Review Letters. American Physical Society, 2011. https://doi.org/10.1103/PhysRevLett.107.113601. ieee: C. Eichler et al., “Observation of two-mode squeezing in the microwave frequency domain,” Physical Review Letters, vol. 107, no. 11. American Physical Society, 2011. ista: Eichler C, Bozyigit D, Lang C, Baur M, Steffen L, Fink JM, Filipp S, Wallraff A. 2011. Observation of two-mode squeezing in the microwave frequency domain. Physical Review Letters. 107(11). mla: Eichler, Christopher, et al. “Observation of Two-Mode Squeezing in the Microwave Frequency Domain.” Physical Review Letters, vol. 107, no. 11, American Physical Society, 2011, doi:10.1103/PhysRevLett.107.113601. short: C. Eichler, D. Bozyigit, C. Lang, M. Baur, L. Steffen, J.M. Fink, S. Filipp, A. Wallraff, Physical Review Letters 107 (2011). date_created: 2018-12-11T11:53:58Z date_published: 2011-09-06T00:00:00Z date_updated: 2021-01-12T06:53:09Z day: '06' doi: 10.1103/PhysRevLett.107.113601 extern: 1 intvolume: ' 107' issue: '11' month: '09' publication: Physical Review Letters publication_status: published publisher: American Physical Society publist_id: '5334' quality_controlled: 0 status: public title: Observation of two-mode squeezing in the microwave frequency domain type: journal_article volume: 107 year: '2011' ... --- _id: '1815' abstract: - lang: eng text: Many membrane channels and receptors exhibit adaptive, or desensitized, response to a strong sustained input stimulus, often supported by protein activity-dependent inactivation. Adaptive response is thought to be related to various cellular functions such as homeostasis and enlargement of dynamic range by background compensation. Here we study the quantitative relation between adaptive response and background compensation within a modeling framework. We show that any particular type of adaptive response is neither sufficient nor necessary for adaptive enlargement of dynamic range. In particular a precise adaptive response, where system activity is maintained at a constant level at steady state, does not ensure a large dynamic range neither in input signal nor in system output. A general mechanism for input dynamic range enlargement can come about from the activity-dependent modulation of protein responsiveness by multiple biochemical modification, regardless of the type of adaptive response it induces. Therefore hierarchical biochemical processes such as methylation and phosphorylation are natural candidates to induce this property in signaling systems. author: - first_name: Tamar full_name: Tamar Friedlander id: 36A5845C-F248-11E8-B48F-1D18A9856A87 last_name: Friedlander - first_name: Naama full_name: Brenner, Naama last_name: Brenner citation: ama: Friedlander T, Brenner N. Adaptive response and enlargement of dynamic range. Mathematical Biosciences and Engineering. 2011;8(2):515-526. doi:10.3934/mbe.2011.8.515 apa: Friedlander, T., & Brenner, N. (2011). Adaptive response and enlargement of dynamic range. Mathematical Biosciences and Engineering. Arizona State University. https://doi.org/10.3934/mbe.2011.8.515 chicago: Friedlander, Tamar, and Naama Brenner. “Adaptive Response and Enlargement of Dynamic Range.” Mathematical Biosciences and Engineering. Arizona State University, 2011. https://doi.org/10.3934/mbe.2011.8.515. ieee: T. Friedlander and N. Brenner, “Adaptive response and enlargement of dynamic range,” Mathematical Biosciences and Engineering, vol. 8, no. 2. Arizona State University, pp. 515–526, 2011. ista: Friedlander T, Brenner N. 2011. Adaptive response and enlargement of dynamic range. Mathematical Biosciences and Engineering. 8(2), 515–526. mla: Friedlander, Tamar, and Naama Brenner. “Adaptive Response and Enlargement of Dynamic Range.” Mathematical Biosciences and Engineering, vol. 8, no. 2, Arizona State University, 2011, pp. 515–26, doi:10.3934/mbe.2011.8.515. short: T. Friedlander, N. Brenner, Mathematical Biosciences and Engineering 8 (2011) 515–526. date_created: 2018-12-11T11:54:10Z date_published: 2011-04-02T00:00:00Z date_updated: 2021-01-12T06:53:23Z day: '02' doi: 10.3934/mbe.2011.8.515 extern: 1 intvolume: ' 8' issue: '2' main_file_link: - open_access: '1' url: http://arxiv.org/abs/1003.2791 month: '04' oa: 1 page: 515 - 526 publication: Mathematical Biosciences and Engineering publication_status: published publisher: Arizona State University publist_id: '5291' quality_controlled: 0 status: public title: Adaptive response and enlargement of dynamic range type: journal_article volume: 8 year: '2011' ... --- _id: '1863' abstract: - lang: eng text: The Levene model is the simplest mathematical model to describe the evolution of gene frequencies in spatially subdivided populations. It provides insight into how locally varying selection promotes a population’s genetic diversity. Despite its simplicity, interesting problems have remained unsolved even in the diallelic case. In this paper we answer an open problem by establishing that for two alleles at one locus and J demes, up to 2J−1 polymorphic equilibria may coexist. We first present a proof for the case of stable monomorphisms and then show that the result also holds for protected alleles. These findings allow us to prove that any odd number (up to 2J−1) of equilibria is possible, before we extend the proof to even numbers. We conclude with some numerical results and show that for J>2, the proportion of parameter space affording this maximum is extremely small. acknowledgement: FWF 21305 author: - first_name: Sebastian full_name: Sebastian Novak id: 461468AE-F248-11E8-B48F-1D18A9856A87 last_name: Novak citation: ama: Novak S. The number of equilibria in the diallelic Levene model with multiple demes. Theoretical Population Biology. 2011;79(3):97-101. doi:10.1016/j.tpb.2010.12.002 apa: Novak, S. (2011). The number of equilibria in the diallelic Levene model with multiple demes. Theoretical Population Biology. Academic Press. https://doi.org/10.1016/j.tpb.2010.12.002 chicago: Novak, Sebastian. “The Number of Equilibria in the Diallelic Levene Model with Multiple Demes.” Theoretical Population Biology. Academic Press, 2011. https://doi.org/10.1016/j.tpb.2010.12.002. ieee: S. Novak, “The number of equilibria in the diallelic Levene model with multiple demes,” Theoretical Population Biology, vol. 79, no. 3. Academic Press, pp. 97–101, 2011. ista: Novak S. 2011. The number of equilibria in the diallelic Levene model with multiple demes. Theoretical Population Biology. 79(3), 97–101. mla: Novak, Sebastian. “The Number of Equilibria in the Diallelic Levene Model with Multiple Demes.” Theoretical Population Biology, vol. 79, no. 3, Academic Press, 2011, pp. 97–101, doi:10.1016/j.tpb.2010.12.002. short: S. Novak, Theoretical Population Biology 79 (2011) 97–101. date_created: 2018-12-11T11:54:25Z date_published: 2011-05-01T00:00:00Z date_updated: 2021-01-12T06:53:42Z day: '01' doi: 10.1016/j.tpb.2010.12.002 extern: 1 intvolume: ' 79' issue: '3' month: '05' page: 97 - 101 publication: Theoretical Population Biology publication_status: published publisher: Academic Press publist_id: '5236' quality_controlled: 0 status: public title: The number of equilibria in the diallelic Levene model with multiple demes tmp: image: /images/cc_by_nc_nd.png legal_code_url: https://creativecommons.org/licenses/by-nc-nd/4.0/legalcode name: Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International (CC BY-NC-ND 4.0) short: CC BY-NC-ND (4.0) type: journal_article volume: 79 year: '2011' ... --- _id: '1975' abstract: - lang: eng text: 'Modern α-proteobacteria are thought to be closely related to the ancient symbiont of eukaryotes, an ancestor of mitochondria. Respiratory complex I from α-proteobacteria and mitochondria is well conserved at the level of the 14 "core" subunits, consistent with that notion. Mitochondrial complex I contains the core subunits, present in all species, and up to 31 "supernumerary" subunits, generally thought to have originated only within eukaryotic lineages. However, the full protein composition of an α-proteobacterial complex I has not been established previously. Here, we report the first purification and characterization of complex I from the α-proteobacterium Paracoccus denitrificans. Single particle electron microscopy shows that the complex has a well defined L-shape. Unexpectedly, in addition to the 14 core subunits, the enzyme also contains homologues of three supernumerary mitochondrial subunits as follows: B17.2, AQDQ/18, and 13 kDa (bovine nomenclature). This finding suggests that evolution of complex I via addition of supernumerary or "accessory" subunits started before the original endosymbiotic event that led to the creation of the eukaryotic cell. It also provides further confirmation that α-proteobacteria are the closest extant relatives of mitochondria.' acknowledgement: 'This work was supported by the Medical Research Council. ' author: - first_name: Chui full_name: Yip, Chui Y last_name: Yip - first_name: Michael full_name: Harbour, Michael E last_name: Harbour - first_name: Kamburapola full_name: Jayawardena, Kamburapola G last_name: Jayawardena - first_name: Ian full_name: Fearnley, Ian M last_name: Fearnley - first_name: Leonid A full_name: Leonid Sazanov id: 338D39FE-F248-11E8-B48F-1D18A9856A87 last_name: Sazanov orcid: 0000-0002-0977-7989 citation: ama: Yip C, Harbour M, Jayawardena K, Fearnley I, Sazanov LA. Evolution of respiratory complex I "Supernumerary" subunits are present in the α-proteobacterial enzyme. Journal of Biological Chemistry. 2011;286(7):5023-5033. doi:10.1074/jbc.M110.194993 apa: Yip, C., Harbour, M., Jayawardena, K., Fearnley, I., & Sazanov, L. A. (2011). Evolution of respiratory complex I "Supernumerary" subunits are present in the α-proteobacterial enzyme. Journal of Biological Chemistry. American Society for Biochemistry and Molecular Biology. https://doi.org/10.1074/jbc.M110.194993 chicago: Yip, Chui, Michael Harbour, Kamburapola Jayawardena, Ian Fearnley, and Leonid A Sazanov. “Evolution of Respiratory Complex I "Supernumerary" Subunits Are Present in the α-Proteobacterial Enzyme.” Journal of Biological Chemistry. American Society for Biochemistry and Molecular Biology, 2011. https://doi.org/10.1074/jbc.M110.194993. ieee: C. Yip, M. Harbour, K. Jayawardena, I. Fearnley, and L. A. Sazanov, “Evolution of respiratory complex I "Supernumerary" subunits are present in the α-proteobacterial enzyme,” Journal of Biological Chemistry, vol. 286, no. 7. American Society for Biochemistry and Molecular Biology, pp. 5023–5033, 2011. ista: Yip C, Harbour M, Jayawardena K, Fearnley I, Sazanov LA. 2011. Evolution of respiratory complex I "Supernumerary" subunits are present in the α-proteobacterial enzyme. Journal of Biological Chemistry. 286(7), 5023–5033. mla: Yip, Chui, et al. “Evolution of Respiratory Complex I "Supernumerary" Subunits Are Present in the α-Proteobacterial Enzyme.” Journal of Biological Chemistry, vol. 286, no. 7, American Society for Biochemistry and Molecular Biology, 2011, pp. 5023–33, doi:10.1074/jbc.M110.194993. short: C. Yip, M. Harbour, K. Jayawardena, I. Fearnley, L.A. Sazanov, Journal of Biological Chemistry 286 (2011) 5023–5033. date_created: 2018-12-11T11:55:00Z date_published: 2011-02-18T00:00:00Z date_updated: 2021-01-12T06:54:27Z day: '18' doi: 10.1074/jbc.M110.194993 extern: 1 intvolume: ' 286' issue: '7' month: '02' page: 5023 - 5033 publication: Journal of Biological Chemistry publication_status: published publisher: American Society for Biochemistry and Molecular Biology publist_id: '5112' quality_controlled: 0 status: public title: Evolution of respiratory complex I "Supernumerary" subunits are present in the α-proteobacterial enzyme type: journal_article volume: 286 year: '2011' ... --- _id: '1973' abstract: - lang: eng text: Complex I is the first and largest enzyme of the respiratory chain, coupling electron transfer between NADH and ubiquinone to the translocation of four protons across the membrane. It has a central role in cellular energy production and has been implicated in many human neurodegenerative diseases. The L-shaped enzyme consists of hydrophilic and membrane domains. Previously, we determined the structure of the hydrophilic domain. Here we report the crystal structure of the Esherichia coli complex I membrane domain at 3.0 Ã. resolution. It includes six subunits, NuoL, NuoM, NuoN, NuoA, NuoJ and NuoK, with 55 transmembrane helices. The fold of the homologous antiporter-like subunits L, M and N is novel, with two inverted structural repeats of five transmembrane helices arranged, unusually, face-to-back. Each repeat includes a discontinuous transmembrane helix and forms half of a channel across the membrane. A network of conserved polar residues connects the two half-channels, completing the proton translocation pathway. Unexpectedly, lysines rather than carboxylate residues act as the main elements of the proton pump in these subunits. The fourth probable proton-translocation channel is at the interface of subunits N, K, J and A. The structure indicates that proton translocation in complex I, uniquely, involves coordinated conformational changes in six symmetrical structural elements. acknowledgement: This work was funded by the Medical Research Council. author: - first_name: Rouslan full_name: Efremov, Rouslan G last_name: Efremov - first_name: Leonid A full_name: Leonid Sazanov id: 338D39FE-F248-11E8-B48F-1D18A9856A87 last_name: Sazanov orcid: 0000-0002-0977-7989 citation: ama: Efremov R, Sazanov LA. Structure of the membrane domain of respiratory complex i. Nature. 2011;476(7361):414-421. doi:10.1038/nature10330 apa: Efremov, R., & Sazanov, L. A. (2011). Structure of the membrane domain of respiratory complex i. Nature. Nature Publishing Group. https://doi.org/10.1038/nature10330 chicago: Efremov, Rouslan, and Leonid A Sazanov. “Structure of the Membrane Domain of Respiratory Complex I.” Nature. Nature Publishing Group, 2011. https://doi.org/10.1038/nature10330. ieee: R. Efremov and L. A. Sazanov, “Structure of the membrane domain of respiratory complex i,” Nature, vol. 476, no. 7361. Nature Publishing Group, pp. 414–421, 2011. ista: Efremov R, Sazanov LA. 2011. Structure of the membrane domain of respiratory complex i. Nature. 476(7361), 414–421. mla: Efremov, Rouslan, and Leonid A. Sazanov. “Structure of the Membrane Domain of Respiratory Complex I.” Nature, vol. 476, no. 7361, Nature Publishing Group, 2011, pp. 414–21, doi:10.1038/nature10330. short: R. Efremov, L.A. Sazanov, Nature 476 (2011) 414–421. date_created: 2018-12-11T11:54:59Z date_published: 2011-08-25T00:00:00Z date_updated: 2021-01-12T06:54:26Z day: '25' doi: 10.1038/nature10330 extern: 1 intvolume: ' 476' issue: '7361' month: '08' page: 414 - 421 publication: Nature publication_status: published publisher: Nature Publishing Group publist_id: '5110' quality_controlled: 0 status: public title: Structure of the membrane domain of respiratory complex i type: journal_article volume: 476 year: '2011' ... --- _id: '1974' abstract: - lang: eng text: Complex I is the first enzyme of the respiratory chain and plays a central role in cellular energy production. It has been implicated in many human neurodegenerative diseases, as well as in ageing. One of the biggest membrane protein complexes, it is an L-shaped assembly consisting of hydrophilic and membrane domains. Previously, we have determined structures of the hydrophilic domain in several redox states. Last year was marked by fascinating breakthroughs in the understanding of the complete structure. We described the architecture of the membrane domain and of the entire bacterial complex I. X-ray analysis of the larger mitochondrial enzyme has also been published. The core subunits of the bacterial and mitochondrial enzymes have remarkably similar structures. The proposed mechanism of coupling between electron transfer and proton translocation involves long-range conformational changes, coordinated in part by a long α-helix, akin to the coupling rod of a steam engine. acknowledgement: The work in authors’ laboratory was funded by the Medical Research Council. author: - first_name: Rouslan full_name: Efremov, Rouslan G last_name: Efremov - first_name: Leonid A full_name: Leonid Sazanov id: 338D39FE-F248-11E8-B48F-1D18A9856A87 last_name: Sazanov orcid: 0000-0002-0977-7989 citation: ama: 'Efremov R, Sazanov LA. Respiratory complex I: “steam engine” of the cell? Current Opinion in Structural Biology. 2011;21(4):532-540. doi:10.1016/j.sbi.2011.07.002' apa: 'Efremov, R., & Sazanov, L. A. (2011). Respiratory complex I: “steam engine” of the cell? Current Opinion in Structural Biology. Elsevier. https://doi.org/10.1016/j.sbi.2011.07.002' chicago: 'Efremov, Rouslan, and Leonid A Sazanov. “Respiratory Complex I: ‘steam Engine’ of the Cell?” Current Opinion in Structural Biology. Elsevier, 2011. https://doi.org/10.1016/j.sbi.2011.07.002.' ieee: 'R. Efremov and L. A. Sazanov, “Respiratory complex I: ‘steam engine’ of the cell?,” Current Opinion in Structural Biology, vol. 21, no. 4. Elsevier, pp. 532–540, 2011.' ista: 'Efremov R, Sazanov LA. 2011. Respiratory complex I: ‘steam engine’ of the cell? Current Opinion in Structural Biology. 21(4), 532–540.' mla: 'Efremov, Rouslan, and Leonid A. Sazanov. “Respiratory Complex I: ‘steam Engine’ of the Cell?” Current Opinion in Structural Biology, vol. 21, no. 4, Elsevier, 2011, pp. 532–40, doi:10.1016/j.sbi.2011.07.002.' short: R. Efremov, L.A. Sazanov, Current Opinion in Structural Biology 21 (2011) 532–540. date_created: 2018-12-11T11:54:59Z date_published: 2011-08-01T00:00:00Z date_updated: 2021-01-12T06:54:27Z day: '01' doi: 10.1016/j.sbi.2011.07.002 extern: 1 intvolume: ' 21' issue: '4' month: '08' page: 532 - 540 publication: Current Opinion in Structural Biology publication_status: published publisher: Elsevier publist_id: '5111' quality_controlled: 0 status: public title: 'Respiratory complex I: ''steam engine'' of the cell?' type: journal_article volume: 21 year: '2011' ... --- _id: '1985' abstract: - lang: eng text: |2- In Escherichia coli, the pole-to-pole oscillation of the Min proteins directs septum formation to midcell, which is required for symmetric cell division. In vitro, protein waves emerge from the self-organization of MinD, a membrane-binding ATPase, and its activator MinE. For wave propagation, the proteins need to cycle through states of collective membrane binding and unbinding. Although MinD presumably undergoes cooperative membrane attachment, it is unclear how synchronous detachment is coordinated. We used confocal and single-molecule microscopy to elucidate the order of events during Min wave propagation. We propose that protein detachment at the rear of the wave, and the formation of the E-ring, are accomplished by two complementary processes: first, local accumulation of MinE due to rapid rebinding, leading to dynamic instability; and second, a structural change induced by membrane-interaction of MinE in an equimolar MinD-MinE (MinDE) complex, which supports the robustness of pattern formation. acknowledgement: This work was also supported by the Max Planck Society (M.L., E.F.-F., P.S.). author: - first_name: Martin full_name: Martin Loose id: 462D4284-F248-11E8-B48F-1D18A9856A87 last_name: Loose orcid: 0000-0001-7309-9724 - first_name: Elisabeth full_name: Fischer-Friedrich, Elisabeth last_name: Fischer Friedrich - first_name: Christoph full_name: Herold, Christoph last_name: Herold - first_name: Karsten full_name: Kruse, Karsten last_name: Kruse - first_name: Petra full_name: 'Schwille, Petra ' last_name: Schwille citation: ama: Loose M, Fischer Friedrich E, Herold C, Kruse K, Schwille P. Min protein patterns emerge from rapid rebinding and membrane interaction of MinE. Nature Structural and Molecular Biology. 2011;18(5):577-583. doi:10.1038/nsmb.2037 apa: Loose, M., Fischer Friedrich, E., Herold, C., Kruse, K., & Schwille, P. (2011). Min protein patterns emerge from rapid rebinding and membrane interaction of MinE. Nature Structural and Molecular Biology. Nature Publishing Group. https://doi.org/10.1038/nsmb.2037 chicago: Loose, Martin, Elisabeth Fischer Friedrich, Christoph Herold, Karsten Kruse, and Petra Schwille. “Min Protein Patterns Emerge from Rapid Rebinding and Membrane Interaction of MinE.” Nature Structural and Molecular Biology. Nature Publishing Group, 2011. https://doi.org/10.1038/nsmb.2037. ieee: M. Loose, E. Fischer Friedrich, C. Herold, K. Kruse, and P. Schwille, “Min protein patterns emerge from rapid rebinding and membrane interaction of MinE,” Nature Structural and Molecular Biology, vol. 18, no. 5. Nature Publishing Group, pp. 577–583, 2011. ista: Loose M, Fischer Friedrich E, Herold C, Kruse K, Schwille P. 2011. Min protein patterns emerge from rapid rebinding and membrane interaction of MinE. Nature Structural and Molecular Biology. 18(5), 577–583. mla: Loose, Martin, et al. “Min Protein Patterns Emerge from Rapid Rebinding and Membrane Interaction of MinE.” Nature Structural and Molecular Biology, vol. 18, no. 5, Nature Publishing Group, 2011, pp. 577–83, doi:10.1038/nsmb.2037. short: M. Loose, E. Fischer Friedrich, C. Herold, K. Kruse, P. Schwille, Nature Structural and Molecular Biology 18 (2011) 577–583. date_created: 2018-12-11T11:55:03Z date_published: 2011-05-01T00:00:00Z date_updated: 2021-01-12T06:54:31Z day: '01' doi: 10.1038/nsmb.2037 extern: 1 intvolume: ' 18' issue: '5' month: '05' page: 577 - 583 publication: Nature Structural and Molecular Biology publication_status: published publisher: Nature Publishing Group publist_id: '5098' quality_controlled: 0 status: public title: Min protein patterns emerge from rapid rebinding and membrane interaction of MinE type: journal_article volume: 18 year: '2011' ... --- _id: '1986' abstract: - lang: eng text: One of the most fundamental features of biological systems is probably their ability to self-organize in space and time on different scales. Despite many elaborate theoretical models of how molecular self-organization can come about, only a few experimental systems of biological origin have so far been rigorously described, due mostly to their inherent complexity. The most promising strategy of modern biophysics is thus to identify minimal biological systems showing self-organized emergent behavior. One of the best-understood examples of protein self-organization, which has recently been successfully reconstituted in vitro, is represented by the oscillations of the Min proteins in Escherichia coli. In this review, we summarize the current understanding of the mechanism of Min protein self-organization in vivo and in vitro. We discuss the potential of the Min oscillations to sense the geometry of the cell and suggest that spontaneous protein waves could be a general means of intracellular organization. We hypothesize that cooperative membrane binding and unbinding, e.g., as an energy-dependent switch, may act as an important regulatory mechanism for protein oscillations and pattern formation in the cell. author: - first_name: Martin full_name: Martin Loose id: 462D4284-F248-11E8-B48F-1D18A9856A87 last_name: Loose orcid: 0000-0001-7309-9724 - first_name: Karsten full_name: Kruse, Karsten last_name: Kruse - first_name: Petra full_name: 'Schwille, Petra ' last_name: Schwille citation: ama: 'Loose M, Kruse K, Schwille P. Protein self-organization: Lessons from the min system. Annual Review of Biophysics. 2011;40(1):315-336. doi:10.1146/annurev-biophys-042910-155332' apa: 'Loose, M., Kruse, K., & Schwille, P. (2011). Protein self-organization: Lessons from the min system. Annual Review of Biophysics. Annual Reviews. https://doi.org/10.1146/annurev-biophys-042910-155332' chicago: 'Loose, Martin, Karsten Kruse, and Petra Schwille. “Protein Self-Organization: Lessons from the Min System.” Annual Review of Biophysics. Annual Reviews, 2011. https://doi.org/10.1146/annurev-biophys-042910-155332.' ieee: 'M. Loose, K. Kruse, and P. Schwille, “Protein self-organization: Lessons from the min system,” Annual Review of Biophysics, vol. 40, no. 1. Annual Reviews, pp. 315–336, 2011.' ista: 'Loose M, Kruse K, Schwille P. 2011. Protein self-organization: Lessons from the min system. Annual Review of Biophysics. 40(1), 315–336.' mla: 'Loose, Martin, et al. “Protein Self-Organization: Lessons from the Min System.” Annual Review of Biophysics, vol. 40, no. 1, Annual Reviews, 2011, pp. 315–36, doi:10.1146/annurev-biophys-042910-155332.' short: M. Loose, K. Kruse, P. Schwille, Annual Review of Biophysics 40 (2011) 315–336. date_created: 2018-12-11T11:55:04Z date_published: 2011-06-09T00:00:00Z date_updated: 2021-01-12T06:54:31Z day: '09' doi: 10.1146/annurev-biophys-042910-155332 extern: 1 intvolume: ' 40' issue: '1' month: '06' page: 315 - 336 publication: Annual Review of Biophysics publication_status: published publisher: Annual Reviews publist_id: '5097' quality_controlled: 0 status: public title: 'Protein self-organization: Lessons from the min system' type: journal_article volume: 40 year: '2011' ... --- _id: '2072' abstract: - lang: eng text: Many species have morphologically and genetically differentiated sex chromosomes, such as the XY pair of mammals. Y chromosomes are often highly degenerated and carry few functional genes, so that XY males have only one copy of most Xlinked genes (whereas females have two). As a result, chromosome-wide mechanisms of dosage compensation, such as the mammalian X-inactivation, often evolve to reestablish expression balance. A similar phenomenon is expected in femaleheterogametic species, where ZW females should suffer from imbalances due to W-chromosome degeneration. However, no global dosage compensation mechanisms have been detected in the two independent ZW systems that have been studied systematically (birds and silkworm), leading to the suggestion that lack of global dosage compensation may be a general feature of female-heterogametic species. However, analyses of other independently evolved ZW systems are required to test if this is the case. In this study, we use published genomic and expression data to test for the presence of global dosage compensation in Schistosoma mansoni, a trematode parasite that causes schistosomiasis in humans. We find that Z-linked expression is reduced relative to autosomal expression in females but not males, consistent with incomplete or localized dosage compensation. This gives further support to the theory that female-heterogametic species may not require global mechanisms of dosage compensation. author: - first_name: Beatriz full_name: Vicoso, Beatriz id: 49E1C5C6-F248-11E8-B48F-1D18A9856A87 last_name: Vicoso orcid: 0000-0002-4579-8306 - first_name: Doris full_name: Bachtrog, Doris last_name: Bachtrog citation: ama: Vicoso B, Bachtrog D. Lack of global dosage compensation in Schistosoma mansoni, a female-heterogametic parasite. Genome Biology and Evolution. 2011;3(1):230-235. doi:10.1093/gbe/evr010 apa: Vicoso, B., & Bachtrog, D. (2011). Lack of global dosage compensation in Schistosoma mansoni, a female-heterogametic parasite. Genome Biology and Evolution. Oxford University Press. https://doi.org/10.1093/gbe/evr010 chicago: Vicoso, Beatriz, and Doris Bachtrog. “Lack of Global Dosage Compensation in Schistosoma Mansoni, a Female-Heterogametic Parasite.” Genome Biology and Evolution. Oxford University Press, 2011. https://doi.org/10.1093/gbe/evr010. ieee: B. Vicoso and D. Bachtrog, “Lack of global dosage compensation in Schistosoma mansoni, a female-heterogametic parasite,” Genome Biology and Evolution, vol. 3, no. 1. Oxford University Press, pp. 230–235, 2011. ista: Vicoso B, Bachtrog D. 2011. Lack of global dosage compensation in Schistosoma mansoni, a female-heterogametic parasite. Genome Biology and Evolution. 3(1), 230–235. mla: Vicoso, Beatriz, and Doris Bachtrog. “Lack of Global Dosage Compensation in Schistosoma Mansoni, a Female-Heterogametic Parasite.” Genome Biology and Evolution, vol. 3, no. 1, Oxford University Press, 2011, pp. 230–35, doi:10.1093/gbe/evr010. short: B. Vicoso, D. Bachtrog, Genome Biology and Evolution 3 (2011) 230–235. date_created: 2018-12-11T11:55:33Z date_published: 2011-02-11T00:00:00Z date_updated: 2021-01-12T06:55:08Z day: '11' ddc: - '570' doi: 10.1093/gbe/evr010 extern: '1' file: - access_level: open_access checksum: 7855c134436e4f6a13d63b6606d7e8dd content_type: application/pdf creator: dernst date_created: 2019-05-10T07:41:28Z date_updated: 2020-07-14T12:45:27Z file_id: '6395' file_name: 2011_GBE_Vicoso.pdf file_size: 212547 relation: main_file file_date_updated: 2020-07-14T12:45:27Z has_accepted_license: '1' intvolume: ' 3' issue: '1' language: - iso: eng license: https://creativecommons.org/licenses/by-nc/4.0/ month: '02' oa: 1 oa_version: Published Version page: 230 - 235 publication: Genome Biology and Evolution publication_status: published publisher: Oxford University Press publist_id: '4966' quality_controlled: '1' status: public title: Lack of global dosage compensation in Schistosoma mansoni, a female-heterogametic parasite tmp: image: /images/cc_by_nc.png legal_code_url: https://creativecommons.org/licenses/by-nc/4.0/legalcode name: Creative Commons Attribution-NonCommercial 4.0 International (CC BY-NC 4.0) short: CC BY-NC (4.0) type: journal_article user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87 volume: 3 year: '2011' ...