---
_id: '9483'
abstract:
- lang: eng
text: Imprinted genes are expressed primarily or exclusively from either the maternal
or paternal allele, a phenomenon that occurs in flowering plants and mammals.
Flowering plant imprinted gene expression has been described primarily in endosperm,
a terminal nutritive tissue consumed by the embryo during seed development or
after germination. Imprinted expression in Arabidopsis thaliana endosperm is orchestrated
by differences in cytosine DNA methylation between the paternal and maternal genomes
as well as by Polycomb group proteins. Currently, only 11 imprinted A. thaliana
genes are known. Here, we use extensive sequencing of cDNA libraries to identify
9 paternally expressed and 34 maternally expressed imprinted genes in A. thaliana
endosperm that are regulated by the DNA-demethylating glycosylase DEMETER, the
DNA methyltransferase MET1, and/or the core Polycomb group protein FIE. These
genes encode transcription factors, proteins involved in hormone signaling, components
of the ubiquitin protein degradation pathway, regulators of histone and DNA methylation,
and small RNA pathway proteins. We also identify maternally expressed genes that
may be regulated by unknown mechanisms or deposited from maternal tissues. We
did not detect any imprinted genes in the embryo. Our results show that imprinted
gene expression is an extensive mechanistically complex phenomenon that likely
affects multiple aspects of seed development.
article_processing_charge: No
article_type: original
author:
- first_name: Tzung-Fu
full_name: Hsieh, Tzung-Fu
last_name: Hsieh
- first_name: Juhyun
full_name: Shin, Juhyun
last_name: Shin
- first_name: Rie
full_name: Uzawa, Rie
last_name: Uzawa
- first_name: Pedro
full_name: Silva, Pedro
last_name: Silva
- first_name: Stephanie
full_name: Cohen, Stephanie
last_name: Cohen
- first_name: Matthew J.
full_name: Bauer, Matthew J.
last_name: Bauer
- first_name: Meryl
full_name: Hashimoto, Meryl
last_name: Hashimoto
- first_name: Ryan C.
full_name: Kirkbride, Ryan C.
last_name: Kirkbride
- first_name: John J.
full_name: Harada, John J.
last_name: Harada
- first_name: Daniel
full_name: Zilberman, Daniel
id: 6973db13-dd5f-11ea-814e-b3e5455e9ed1
last_name: Zilberman
orcid: 0000-0002-0123-8649
- first_name: Robert L.
full_name: Fischer, Robert L.
last_name: Fischer
citation:
ama: Hsieh T-F, Shin J, Uzawa R, et al. Regulation of imprinted gene expression
in Arabidopsis endosperm. Proceedings of the National Academy of Sciences.
2011;108(5):1755-1762. doi:10.1073/pnas.1019273108
apa: Hsieh, T.-F., Shin, J., Uzawa, R., Silva, P., Cohen, S., Bauer, M. J., … Fischer,
R. L. (2011). Regulation of imprinted gene expression in Arabidopsis endosperm.
Proceedings of the National Academy of Sciences. National Academy of Sciences.
https://doi.org/10.1073/pnas.1019273108
chicago: Hsieh, Tzung-Fu, Juhyun Shin, Rie Uzawa, Pedro Silva, Stephanie Cohen,
Matthew J. Bauer, Meryl Hashimoto, et al. “Regulation of Imprinted Gene Expression
in Arabidopsis Endosperm.” Proceedings of the National Academy of Sciences.
National Academy of Sciences, 2011. https://doi.org/10.1073/pnas.1019273108.
ieee: T.-F. Hsieh et al., “Regulation of imprinted gene expression in Arabidopsis
endosperm,” Proceedings of the National Academy of Sciences, vol. 108,
no. 5. National Academy of Sciences, pp. 1755–1762, 2011.
ista: Hsieh T-F, Shin J, Uzawa R, Silva P, Cohen S, Bauer MJ, Hashimoto M, Kirkbride
RC, Harada JJ, Zilberman D, Fischer RL. 2011. Regulation of imprinted gene expression
in Arabidopsis endosperm. Proceedings of the National Academy of Sciences. 108(5),
1755–1762.
mla: Hsieh, Tzung-Fu, et al. “Regulation of Imprinted Gene Expression in Arabidopsis
Endosperm.” Proceedings of the National Academy of Sciences, vol. 108,
no. 5, National Academy of Sciences, 2011, pp. 1755–62, doi:10.1073/pnas.1019273108.
short: T.-F. Hsieh, J. Shin, R. Uzawa, P. Silva, S. Cohen, M.J. Bauer, M. Hashimoto,
R.C. Kirkbride, J.J. Harada, D. Zilberman, R.L. Fischer, Proceedings of the National
Academy of Sciences 108 (2011) 1755–1762.
date_created: 2021-06-07T07:40:38Z
date_published: 2011-02-01T00:00:00Z
date_updated: 2021-12-14T08:33:49Z
day: '01'
department:
- _id: DaZi
doi: 10.1073/pnas.1019273108
extern: '1'
external_id:
pmid:
- '21257907'
intvolume: ' 108'
issue: '5'
language:
- iso: eng
main_file_link:
- open_access: '1'
url: https://doi.org/10.1073/pnas.1019273108
month: '02'
oa: 1
oa_version: Published Version
page: 1755-1762
pmid: 1
publication: Proceedings of the National Academy of Sciences
publication_identifier:
eissn:
- 1091-6490
issn:
- 0027-8424
publication_status: published
publisher: National Academy of Sciences
quality_controlled: '1'
scopus_import: '1'
status: public
title: Regulation of imprinted gene expression in Arabidopsis endosperm
type: journal_article
user_id: 8b945eb4-e2f2-11eb-945a-df72226e66a9
volume: 108
year: '2011'
...
---
_id: '967'
abstract:
- lang: eng
text: Motivated by recent experiments on the material Ba3NiSb 2O9, we consider a
spin-one quantum antiferromagnet on a triangular lattice with the Heisenberg bilinear
and biquadratic exchange interactions and a single-ion anisotropy. Using a fermionic
"triplon" representation for spins, we study the phase diagram within
mean-field theory. In addition to a fully gapped spin-liquid ground state, we
find a state where one gapless triplon mode with a Fermi surface coexists with
d+id topological pairing of the other triplons. Despite the existence of a Fermi
surface, this ground state has fully gapped bulk spin excitations. Such a state
has linear in-temperature specific heat and constant in-plane spin susceptibility,
with an unusually high Wilson ratio.
author:
- first_name: Maksym
full_name: Maksym Serbyn
id: 47809E7E-F248-11E8-B48F-1D18A9856A87
last_name: Serbyn
orcid: 0000-0002-2399-5827
- first_name: Todadri
full_name: Senthil, Todadri S
last_name: Senthil
- first_name: Patrick
full_name: Lee, Patrick
last_name: Lee
citation:
ama: Serbyn M, Senthil T, Lee P. Exotic S=1 spin-liquid state with fermionic excitations
on the triangular lattice. Physical Review B - Condensed Matter and Materials
Physics. 2011;84(18). doi:10.1103/PhysRevB.84.180403
apa: Serbyn, M., Senthil, T., & Lee, P. (2011). Exotic S=1 spin-liquid state
with fermionic excitations on the triangular lattice. Physical Review B - Condensed
Matter and Materials Physics. American Physical Society. https://doi.org/10.1103/PhysRevB.84.180403
chicago: Serbyn, Maksym, Todadri Senthil, and Patrick Lee. “Exotic S=1 Spin-Liquid
State with Fermionic Excitations on the Triangular Lattice.” Physical Review
B - Condensed Matter and Materials Physics. American Physical Society, 2011.
https://doi.org/10.1103/PhysRevB.84.180403.
ieee: M. Serbyn, T. Senthil, and P. Lee, “Exotic S=1 spin-liquid state with fermionic
excitations on the triangular lattice,” Physical Review B - Condensed Matter
and Materials Physics, vol. 84, no. 18. American Physical Society, 2011.
ista: Serbyn M, Senthil T, Lee P. 2011. Exotic S=1 spin-liquid state with fermionic
excitations on the triangular lattice. Physical Review B - Condensed Matter and
Materials Physics. 84(18).
mla: Serbyn, Maksym, et al. “Exotic S=1 Spin-Liquid State with Fermionic Excitations
on the Triangular Lattice.” Physical Review B - Condensed Matter and Materials
Physics, vol. 84, no. 18, American Physical Society, 2011, doi:10.1103/PhysRevB.84.180403.
short: M. Serbyn, T. Senthil, P. Lee, Physical Review B - Condensed Matter and Materials
Physics 84 (2011).
date_created: 2018-12-11T11:49:27Z
date_published: 2011-11-03T00:00:00Z
date_updated: 2021-01-12T08:22:18Z
day: '03'
doi: 10.1103/PhysRevB.84.180403
extern: 1
intvolume: ' 84'
issue: '18'
main_file_link:
- open_access: '1'
url: https://arxiv.org/abs/1108.3070
month: '11'
oa: 1
publication: Physical Review B - Condensed Matter and Materials Physics
publication_status: published
publisher: American Physical Society
publist_id: '6432'
quality_controlled: 0
status: public
title: Exotic S=1 spin-liquid state with fermionic excitations on the triangular lattice
type: journal_article
volume: 84
year: '2011'
...
---
_id: '969'
abstract:
- lang: eng
text: We investigate the isotope effect on the London penetration depth of a superconductor
which measures n S/m*, the ratio of superfluid density to effective mass. We use
a simplified model of electrons weakly coupled to a single phonon frequency ω
E, but assume that the energy gap Δ does not have any isotope effect. Nevertheless,
we find an isotope effect for n S/m* which is significant if Δ is sufficiently
large that it becomes comparable to ω E, a regime of interest to high-T c cuprate
superconductors and possibly other families of unconventional superconductors
with relatively high T c. Our model is too simple to describe the cuprates and
it gives the wrong sign of the isotope effect when compared with experiment, but
it is a proof of principle that the isotope effect exists for n S/m* in materials
where the pairing gap and T c are not of phonon origin and have no isotope effect.
author:
- first_name: Maksym
full_name: Maksym Serbyn
id: 47809E7E-F248-11E8-B48F-1D18A9856A87
last_name: Serbyn
orcid: 0000-0002-2399-5827
- first_name: Patrick
full_name: Lee, Patrick
last_name: Lee
citation:
ama: Serbyn M, Lee P. Isotope effect on the superfluid density in conventional and
high-temperature superconductors. Physical Review B - Condensed Matter and
Materials Physics. 2011;83(2). doi:10.1103/PhysRevB.83.024506
apa: Serbyn, M., & Lee, P. (2011). Isotope effect on the superfluid density
in conventional and high-temperature superconductors. Physical Review B - Condensed
Matter and Materials Physics. American Physical Society. https://doi.org/10.1103/PhysRevB.83.024506
chicago: Serbyn, Maksym, and Patrick Lee. “Isotope Effect on the Superfluid Density
in Conventional and High-Temperature Superconductors.” Physical Review B -
Condensed Matter and Materials Physics. American Physical Society, 2011. https://doi.org/10.1103/PhysRevB.83.024506.
ieee: M. Serbyn and P. Lee, “Isotope effect on the superfluid density in conventional
and high-temperature superconductors,” Physical Review B - Condensed Matter
and Materials Physics, vol. 83, no. 2. American Physical Society, 2011.
ista: Serbyn M, Lee P. 2011. Isotope effect on the superfluid density in conventional
and high-temperature superconductors. Physical Review B - Condensed Matter and
Materials Physics. 83(2).
mla: Serbyn, Maksym, and Patrick Lee. “Isotope Effect on the Superfluid Density
in Conventional and High-Temperature Superconductors.” Physical Review B -
Condensed Matter and Materials Physics, vol. 83, no. 2, American Physical
Society, 2011, doi:10.1103/PhysRevB.83.024506.
short: M. Serbyn, P. Lee, Physical Review B - Condensed Matter and Materials Physics
83 (2011).
date_created: 2018-12-11T11:49:28Z
date_published: 2011-01-19T00:00:00Z
date_updated: 2021-01-12T08:22:19Z
day: '19'
doi: 10.1103/PhysRevB.83.024506
extern: 1
intvolume: ' 83'
issue: '2'
main_file_link:
- open_access: '1'
url: https://arxiv.org/abs/1009.2429
month: '01'
oa: 1
publication: Physical Review B - Condensed Matter and Materials Physics
publication_status: published
publisher: American Physical Society
publist_id: '6434'
quality_controlled: 0
status: public
title: Isotope effect on the superfluid density in conventional and high-temperature
superconductors
type: journal_article
volume: 83
year: '2011'
...
---
_id: '8471'
abstract:
- lang: eng
text: Despite the importance of protein fibrils in the context of conformational
diseases, information on their structure is still sparse. Hydrogen/deuterium exchange
measurements of backbone amide protons allow the identification hydrogen-bonding
patterns and reveal pertinent information on the amyloid β-sheet architecture.
However, they provide only little information on the identity of residues exposed
to solvent or buried inside the fibril core. NMR spectroscopy is a potent method
for identifying solvent-accessible residues in proteins via observation of polarization
transfer between chemically exchanging side-chain protons and water protons. We
show here that the combined use of highly deuterated samples and fast magic-angle
spinning greatly attenuates unwanted spin diffusion and allows identification
of polarization exchange with the solvent in a site-specific manner. We apply
this measurement protocol to HET-s(218–289) prion fibrils under different conditions
(including physiological pH, where protofibrils assemble together into thicker
fibrils) and demonstrate that each protofibril of HET-s(218–289), is surrounded
by water, thus excluding the existence of extended dry interfibril contacts. We
also show that exchangeable side-chain protons inside the hydrophobic core of
HET-s(218–289) do not exchange over time intervals of weeks to months. The experiments
proposed in this study can provide insight into the detailed structural features
of amyloid fibrils in general.
article_processing_charge: No
article_type: original
author:
- first_name: Hélène
full_name: Van Melckebeke, Hélène
last_name: Van Melckebeke
- first_name: Paul
full_name: Schanda, Paul
id: 7B541462-FAF6-11E9-A490-E8DFE5697425
last_name: Schanda
orcid: 0000-0002-9350-7606
- first_name: Julia
full_name: Gath, Julia
last_name: Gath
- first_name: Christian
full_name: Wasmer, Christian
last_name: Wasmer
- first_name: René
full_name: Verel, René
last_name: Verel
- first_name: Adam
full_name: Lange, Adam
last_name: Lange
- first_name: Beat H.
full_name: Meier, Beat H.
last_name: Meier
- first_name: Anja
full_name: Böckmann, Anja
last_name: Böckmann
citation:
ama: Van Melckebeke H, Schanda P, Gath J, et al. Probing water accessibility in
HET-s(218–289) amyloid fibrils by solid-state NMR. Journal of Molecular Biology.
2011;405(3):765-772. doi:10.1016/j.jmb.2010.11.004
apa: Van Melckebeke, H., Schanda, P., Gath, J., Wasmer, C., Verel, R., Lange, A.,
… Böckmann, A. (2011). Probing water accessibility in HET-s(218–289) amyloid fibrils
by solid-state NMR. Journal of Molecular Biology. Elsevier. https://doi.org/10.1016/j.jmb.2010.11.004
chicago: Van Melckebeke, Hélène, Paul Schanda, Julia Gath, Christian Wasmer, René
Verel, Adam Lange, Beat H. Meier, and Anja Böckmann. “Probing Water Accessibility
in HET-s(218–289) Amyloid Fibrils by Solid-State NMR.” Journal of Molecular
Biology. Elsevier, 2011. https://doi.org/10.1016/j.jmb.2010.11.004.
ieee: H. Van Melckebeke et al., “Probing water accessibility in HET-s(218–289)
amyloid fibrils by solid-state NMR,” Journal of Molecular Biology, vol.
405, no. 3. Elsevier, pp. 765–772, 2011.
ista: Van Melckebeke H, Schanda P, Gath J, Wasmer C, Verel R, Lange A, Meier BH,
Böckmann A. 2011. Probing water accessibility in HET-s(218–289) amyloid fibrils
by solid-state NMR. Journal of Molecular Biology. 405(3), 765–772.
mla: Van Melckebeke, Hélène, et al. “Probing Water Accessibility in HET-s(218–289)
Amyloid Fibrils by Solid-State NMR.” Journal of Molecular Biology, vol.
405, no. 3, Elsevier, 2011, pp. 765–72, doi:10.1016/j.jmb.2010.11.004.
short: H. Van Melckebeke, P. Schanda, J. Gath, C. Wasmer, R. Verel, A. Lange, B.H.
Meier, A. Böckmann, Journal of Molecular Biology 405 (2011) 765–772.
date_created: 2020-09-18T10:11:03Z
date_published: 2011-01-21T00:00:00Z
date_updated: 2021-01-12T08:19:30Z
day: '21'
doi: 10.1016/j.jmb.2010.11.004
extern: '1'
intvolume: ' 405'
issue: '3'
language:
- iso: eng
month: '01'
oa_version: None
page: 765-772
publication: Journal of Molecular Biology
publication_identifier:
issn:
- 0022-2836
publication_status: published
publisher: Elsevier
quality_controlled: '1'
status: public
title: Probing water accessibility in HET-s(218–289) amyloid fibrils by solid-state
NMR
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 405
year: '2011'
...
---
_id: '8505'
abstract:
- lang: eng
text: The classical principle of least action says that orbits of mechanical systems
extremize action; an important subclass are those orbits that minimize action.
In this paper we utilize this principle along with Aubry-Mather theory to construct
(Birkhoff) regions of instability for a certain three-body problem, given by a
Hamiltonian system of 2 degrees of freedom. We believe that these methods can
be applied to construct instability regions for a variety of Hamiltonian systems
with 2 degrees of freedom. The Hamiltonian model we consider describes dynamics
of a Sun-Jupiter-comet system, and under some simplifying assumptions, we show
the existence of instabilities for the orbit of the comet. In particular, we show
that a comet which starts close to an orbit in the shape of an ellipse of eccentricity
e=0.66 can increase in eccentricity up to e=0.96. In the sequels to this paper,
we extend the result to beyond e=1 and show the existence of ejection orbits.
Such orbits are initially well within the range of our solar system. This might
give an indication of why most objects rotating around the Sun in our solar system
have relatively low eccentricity.
article_processing_charge: No
article_type: original
author:
- first_name: Joseph
full_name: Galante, Joseph
last_name: Galante
- first_name: Vadim
full_name: Kaloshin, Vadim
id: FE553552-CDE8-11E9-B324-C0EBE5697425
last_name: Kaloshin
orcid: 0000-0002-6051-2628
citation:
ama: Galante J, Kaloshin V. Destruction of invariant curves in the restricted circular
planar three-body problem by using comparison of action. Duke Mathematical
Journal. 2011;159(2):275-327. doi:10.1215/00127094-1415878
apa: Galante, J., & Kaloshin, V. (2011). Destruction of invariant curves in
the restricted circular planar three-body problem by using comparison of action.
Duke Mathematical Journal. Duke University Press. https://doi.org/10.1215/00127094-1415878
chicago: Galante, Joseph, and Vadim Kaloshin. “Destruction of Invariant Curves in
the Restricted Circular Planar Three-Body Problem by Using Comparison of Action.”
Duke Mathematical Journal. Duke University Press, 2011. https://doi.org/10.1215/00127094-1415878.
ieee: J. Galante and V. Kaloshin, “Destruction of invariant curves in the restricted
circular planar three-body problem by using comparison of action,” Duke Mathematical
Journal, vol. 159, no. 2. Duke University Press, pp. 275–327, 2011.
ista: Galante J, Kaloshin V. 2011. Destruction of invariant curves in the restricted
circular planar three-body problem by using comparison of action. Duke Mathematical
Journal. 159(2), 275–327.
mla: Galante, Joseph, and Vadim Kaloshin. “Destruction of Invariant Curves in the
Restricted Circular Planar Three-Body Problem by Using Comparison of Action.”
Duke Mathematical Journal, vol. 159, no. 2, Duke University Press, 2011,
pp. 275–327, doi:10.1215/00127094-1415878.
short: J. Galante, V. Kaloshin, Duke Mathematical Journal 159 (2011) 275–327.
date_created: 2020-09-18T10:47:41Z
date_published: 2011-08-04T00:00:00Z
date_updated: 2021-01-12T08:19:45Z
day: '04'
doi: 10.1215/00127094-1415878
extern: '1'
intvolume: ' 159'
issue: '2'
keyword:
- General Mathematics
language:
- iso: eng
month: '08'
oa_version: None
page: 275-327
publication: Duke Mathematical Journal
publication_identifier:
issn:
- 0012-7094
publication_status: published
publisher: Duke University Press
quality_controlled: '1'
status: public
title: Destruction of invariant curves in the restricted circular planar three-body
problem by using comparison of action
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 159
year: '2011'
...