--- _id: '1299' abstract: - lang: eng text: Recent experiments have shown that motion detection in Drosophila starts with splitting the visual input into two parallel channels encoding brightness increments (ON) or decrements (OFF). This suggests the existence of either two (ON-ON, OFF-OFF) or four (for all pairwise interactions) separate motion detectors. To decide between these possibilities, we stimulated flies using sequences of ON and OFF brightness pulses while recording from motion-sensitive tangential cells. We found direction-selective responses to sequences of same sign (ON-ON, OFF-OFF), but not of opposite sign (ON-OFF, OFF-ON), refuting the existence of four separate detectors. Based on further measurements, we propose a model that reproduces a variety of additional experimental data sets, including ones that were previously interpreted as support for four separate detectors. Our experiments and the derived model mark an important step in guiding further dissection of the fly motion detection circuit. author: - first_name: Hubert full_name: Eichner, Hubert last_name: Eichner - first_name: Maximilian A full_name: Maximilian Jösch id: 2BD278E6-F248-11E8-B48F-1D18A9856A87 last_name: Jösch orcid: 0000-0002-3937-1330 - first_name: Bettina full_name: Schnell, Bettina last_name: Schnell - first_name: Dierk full_name: Reiff, Dierk F last_name: Reiff - first_name: Alexander full_name: Borst, Alexander last_name: Borst citation: ama: Eichner H, Jösch MA, Schnell B, Reiff D, Borst A. Internal structure of the fly elementary motion detector. Neuron. 2011;70(6):1155-1164. doi:10.1016/j.neuron.2011.03.028 apa: Eichner, H., Jösch, M. A., Schnell, B., Reiff, D., & Borst, A. (2011). Internal structure of the fly elementary motion detector. Neuron. Elsevier. https://doi.org/10.1016/j.neuron.2011.03.028 chicago: Eichner, Hubert, Maximilian A Jösch, Bettina Schnell, Dierk Reiff, and Alexander Borst. “Internal Structure of the Fly Elementary Motion Detector.” Neuron. Elsevier, 2011. https://doi.org/10.1016/j.neuron.2011.03.028. ieee: H. Eichner, M. A. Jösch, B. Schnell, D. Reiff, and A. Borst, “Internal structure of the fly elementary motion detector,” Neuron, vol. 70, no. 6. Elsevier, pp. 1155–1164, 2011. ista: Eichner H, Jösch MA, Schnell B, Reiff D, Borst A. 2011. Internal structure of the fly elementary motion detector. Neuron. 70(6), 1155–1164. mla: Eichner, Hubert, et al. “Internal Structure of the Fly Elementary Motion Detector.” Neuron, vol. 70, no. 6, Elsevier, 2011, pp. 1155–64, doi:10.1016/j.neuron.2011.03.028. short: H. Eichner, M.A. Jösch, B. Schnell, D. Reiff, A. Borst, Neuron 70 (2011) 1155–1164. date_created: 2018-12-11T11:51:14Z date_published: 2011-06-23T00:00:00Z date_updated: 2021-01-12T06:49:43Z day: '23' doi: 10.1016/j.neuron.2011.03.028 extern: 1 intvolume: ' 70' issue: '6' month: '06' page: 1155 - 1164 publication: Neuron publication_status: published publisher: Elsevier publist_id: '5969' quality_controlled: 0 status: public title: Internal structure of the fly elementary motion detector type: journal_article volume: 70 year: '2011' ... --- _id: '1467' abstract: - lang: eng text: We propose a general conjecture for the mixed Hodge polynomial of the generic character varieties of representations of the fundamental group of a Riemann surface of genus g to GLn(C) with fixed generic semisimple conjugacy classes at k punctures. This conjecture generalizes the Cauchy identity for Macdonald polynomials and is a common generalization of two formulas that we prove in this paper. The first is a formula for the E-polynomial of these character varieties which we obtain using the character table of GLn(Fq). We use this formula to compute the Euler characteristic of character varieties. The second formula gives the Poincaré polynomial of certain associated quiver varieties which we obtain using the character table of gln(Fq). In the last main result we prove that the Poincaré polynomials of the quiver varieties equal certain multiplicities in the tensor product of irreducible characters of GLn(Fq). As a consequence we find a curious connection between Kac-Moody algebras associated with comet-shaped, and typically wild, quivers and the representation theory of GLn(Fq). acknowledgement: |- Hausel’s work was supported by National Science Foundation grants DMS-0305505 and DMS-0604775, by an Alfred Sloan Fellowship, and by a Royal Society University Research Fellowship. Letellier’s work supported by Agence Nationale de la Recherche grant ANR-09-JCJC-0102-01. Rodriguez-Villegas’s work supported by National Science Foundation grant DMS-0200605, by an FRA from the University of Texas at Austin, by EPSRC grant EP/G027110/1, by visiting fellowships at All Souls and Wadham Colleges in Oxford, and by a Research Scholarship from the Clay Mathematical Institute. author: - first_name: Tamas full_name: Tamas Hausel id: 4A0666D8-F248-11E8-B48F-1D18A9856A87 last_name: Hausel - first_name: Emmanuel full_name: Letellier, Emmanuel last_name: Letellier - first_name: Fernando full_name: Rodríguez Villegas, Fernando last_name: Rodríguez Villegas citation: ama: Hausel T, Letellier E, Rodríguez Villegas F. Arithmetic harmonic analysis on character and quiver varieties. Duke Mathematical Journal. 2011;160(2):323-400. doi:10.1215/00127094-1444258 apa: Hausel, T., Letellier, E., & Rodríguez Villegas, F. (2011). Arithmetic harmonic analysis on character and quiver varieties. Duke Mathematical Journal. Duke University Press. https://doi.org/10.1215/00127094-1444258 chicago: Hausel, Tamás, Emmanuel Letellier, and Fernando Rodríguez Villegas. “Arithmetic Harmonic Analysis on Character and Quiver Varieties.” Duke Mathematical Journal. Duke University Press, 2011. https://doi.org/10.1215/00127094-1444258. ieee: T. Hausel, E. Letellier, and F. Rodríguez Villegas, “Arithmetic harmonic analysis on character and quiver varieties,” Duke Mathematical Journal, vol. 160, no. 2. Duke University Press, pp. 323–400, 2011. ista: Hausel T, Letellier E, Rodríguez Villegas F. 2011. Arithmetic harmonic analysis on character and quiver varieties. Duke Mathematical Journal. 160(2), 323–400. mla: Hausel, Tamás, et al. “Arithmetic Harmonic Analysis on Character and Quiver Varieties.” Duke Mathematical Journal, vol. 160, no. 2, Duke University Press, 2011, pp. 323–400, doi:10.1215/00127094-1444258. short: T. Hausel, E. Letellier, F. Rodríguez Villegas, Duke Mathematical Journal 160 (2011) 323–400. date_created: 2018-12-11T11:52:11Z date_published: 2011-01-01T00:00:00Z date_updated: 2021-01-12T06:50:56Z day: '01' doi: 10.1215/00127094-1444258 extern: 1 intvolume: ' 160' issue: '2' main_file_link: - open_access: '1' url: http://arxiv.org/abs/0810.2076 month: '01' oa: 1 page: 323 - 400 publication: Duke Mathematical Journal publication_status: published publisher: Duke University Press publist_id: '5728' quality_controlled: 0 status: public title: Arithmetic harmonic analysis on character and quiver varieties type: journal_article volume: 160 year: '2011' ... --- _id: '1723' abstract: - lang: eng text: The emergence of differences in the arrangement of cells is the first step towards the establishment of many organs. Understanding this process is limited by the lack of systematic characterization of epithelial organisation. Here we apply network theory at the scale of individual cells to uncover patterns in cell-to-cell contacts that govern epithelial organisation. We provide an objective characterisation of epithelia using network representation, where cells are nodes and cell contacts are links. The features of individual cells, together with attributes of the cellular network, produce a defining signature that distinguishes epithelia from different organs, species, developmental stages and genetic conditions. The approach permits characterization, quantification and classification of normal and perturbed epithelia, and establishes a framework for understanding molecular mechanisms that underpin the architecture of complex tissues. acknowledgement: We acknowledge the MRC for funding, M.M.B. acknowledges Darwin College, EMBO YIP and Schlumberger Ltd for support. L.M.E. is funded by the Marie Curie and the EMBO fellowships. L.d.F.C. is grateful to FAPESP (05/00587-5) and CNPq (301303/06-1) for financial support. Part of this work was performed during a Visiting Scholarship to L.d.F.C. from St Catharine's College, University of Cambridge. J.B. is supported by the MRC (UK) and A.K. by a FEBS fellowship author: - first_name: Luis full_name: Escudero, Luis M last_name: Escudero - first_name: Luciano full_name: Costa, Luciano last_name: Costa - first_name: Anna full_name: Anna Kicheva id: 3959A2A0-F248-11E8-B48F-1D18A9856A87 last_name: Kicheva orcid: 0000-0003-4509-4998 - first_name: James full_name: Briscoe, James last_name: Briscoe - first_name: Matthew full_name: Freeman, Matthew last_name: Freeman - first_name: Madan full_name: Babu, Madan M last_name: Babu citation: ama: Escudero L, Costa L, Kicheva A, Briscoe J, Freeman M, Babu M. Epithelial organisation revealed by a network of cellular contacts. Nature Communications. 2011;2(1). doi:10.1038/ncomms1536 apa: Escudero, L., Costa, L., Kicheva, A., Briscoe, J., Freeman, M., & Babu, M. (2011). Epithelial organisation revealed by a network of cellular contacts. Nature Communications. Nature Publishing Group. https://doi.org/10.1038/ncomms1536 chicago: Escudero, Luis, Luciano Costa, Anna Kicheva, James Briscoe, Matthew Freeman, and Madan Babu. “Epithelial Organisation Revealed by a Network of Cellular Contacts.” Nature Communications. Nature Publishing Group, 2011. https://doi.org/10.1038/ncomms1536. ieee: L. Escudero, L. Costa, A. Kicheva, J. Briscoe, M. Freeman, and M. Babu, “Epithelial organisation revealed by a network of cellular contacts,” Nature Communications, vol. 2, no. 1. Nature Publishing Group, 2011. ista: Escudero L, Costa L, Kicheva A, Briscoe J, Freeman M, Babu M. 2011. Epithelial organisation revealed by a network of cellular contacts. Nature Communications. 2(1). mla: Escudero, Luis, et al. “Epithelial Organisation Revealed by a Network of Cellular Contacts.” Nature Communications, vol. 2, no. 1, Nature Publishing Group, 2011, doi:10.1038/ncomms1536. short: L. Escudero, L. Costa, A. Kicheva, J. Briscoe, M. Freeman, M. Babu, Nature Communications 2 (2011). date_created: 2018-12-11T11:53:40Z date_published: 2011-01-01T00:00:00Z date_updated: 2021-01-12T06:52:46Z day: '01' doi: 10.1038/ncomms1536 extern: 1 intvolume: ' 2' issue: '1' month: '01' publication: Nature Communications publication_status: published publisher: Nature Publishing Group publist_id: '5405' quality_controlled: 0 status: public title: Epithelial organisation revealed by a network of cellular contacts type: journal_article volume: 2 year: '2011' ... --- _id: '1724' abstract: - lang: eng text: Morphogens, such as Decapentaplegic (Dpp) in the fly imaginal discs, form graded concentration profiles that control patterning and growth of developing organs. In the imaginal discs, proliferative growth is homogeneous in space, posing the conundrum of how morphogen concentration gradients could control position-independent growth. To understand the mechanism of proliferation control by the Dpp gradient, we quantified Dpp concentration and signaling levels during wing disc growth. Both Dpp concentration and signaling gradients scale with tissue size during development. On average, cells divide when Dpp signaling levels have increased by 50%. Our observations are consistent with a growth control mechanism based on temporal changes of cellular morphogen signaling levels. For a scaling gradient, this mechanism generates position-independent growth rates. acknowledgement: P.M., T.B., and F.J. were supported by the Max-Planck-Gesellschaft. O.W., A.K., C.S., and M.G.-G. were supported by Geneva University and by European Research Council advanced investigator grant (SARA), SystemsX (LipidX), Swiss National Science Foundation (SNF), National Centre of Competence in Research (NCCR) chemical biology and Frontiers in Genetics and R'equip grants author: - first_name: Ortrud full_name: Wartlick, Ortrud last_name: Wartlick - first_name: Peer full_name: Mumcu, Peer last_name: Mumcu - first_name: Anna full_name: Anna Kicheva id: 3959A2A0-F248-11E8-B48F-1D18A9856A87 last_name: Kicheva orcid: 0000-0003-4509-4998 - first_name: Thomas full_name: Bittig, Thomas last_name: Bittig - first_name: Carole full_name: Seum, Carole last_name: Seum - first_name: Frank full_name: Jülicher, Frank last_name: Jülicher - first_name: Marcos full_name: González-Gaitán, Marcos A last_name: González Gaitán citation: ama: Wartlick O, Mumcu P, Kicheva A, et al. Dynamics of Dpp signaling and proliferation control. Science. 2011;331(6021):1154-1159. doi:10.1126/science.1200037 apa: Wartlick, O., Mumcu, P., Kicheva, A., Bittig, T., Seum, C., Jülicher, F., & González Gaitán, M. (2011). Dynamics of Dpp signaling and proliferation control. Science. American Association for the Advancement of Science. https://doi.org/10.1126/science.1200037 chicago: Wartlick, Ortrud, Peer Mumcu, Anna Kicheva, Thomas Bittig, Carole Seum, Frank Jülicher, and Marcos González Gaitán. “Dynamics of Dpp Signaling and Proliferation Control.” Science. American Association for the Advancement of Science, 2011. https://doi.org/10.1126/science.1200037. ieee: O. Wartlick et al., “Dynamics of Dpp signaling and proliferation control,” Science, vol. 331, no. 6021. American Association for the Advancement of Science, pp. 1154–1159, 2011. ista: Wartlick O, Mumcu P, Kicheva A, Bittig T, Seum C, Jülicher F, González Gaitán M. 2011. Dynamics of Dpp signaling and proliferation control. Science. 331(6021), 1154–1159. mla: Wartlick, Ortrud, et al. “Dynamics of Dpp Signaling and Proliferation Control.” Science, vol. 331, no. 6021, American Association for the Advancement of Science, 2011, pp. 1154–59, doi:10.1126/science.1200037. short: O. Wartlick, P. Mumcu, A. Kicheva, T. Bittig, C. Seum, F. Jülicher, M. González Gaitán, Science 331 (2011) 1154–1159. date_created: 2018-12-11T11:53:40Z date_published: 2011-03-04T00:00:00Z date_updated: 2021-01-12T06:52:46Z day: '04' doi: 10.1126/science.1200037 extern: 1 intvolume: ' 331' issue: '6021' month: '03' page: 1154 - 1159 publication: Science publication_status: published publisher: American Association for the Advancement of Science publist_id: '5406' quality_controlled: 0 status: public title: Dynamics of Dpp signaling and proliferation control type: journal_article volume: 331 year: '2011' ... --- _id: '1754' abstract: - lang: eng text: 'We report on a technique enabling electrical control of the contact silicidation process in silicon nanowire devices. Undoped silicon nanowires were contacted by pairs of nickel electrodes and each contact was selectively silicided by means of the Joule effect. By a realtime monitoring of the nanowire electrical resistance during the contact silicidation process we were able to fabricate nickel-silicide/silicon/nickel- silicide devices with controlled silicon channel length down to 8 nm. ' acknowledgement: This work was supported by the Agence Nationale de la Recherche (ANR) through the ACCESS and COHESION projects and by the European Commission through the Chemtronics program MEST-CT-2005-020513 author: - first_name: Massimo full_name: Mongillo, Massimo last_name: Mongillo - first_name: Panayotis full_name: Spathis, Panayotis last_name: Spathis - first_name: Georgios full_name: Katsaros, Georgios id: 38DB5788-F248-11E8-B48F-1D18A9856A87 last_name: Katsaros - first_name: Pascal full_name: Gentile, Pascal last_name: Gentile - first_name: Marc full_name: Sanquer, Marc last_name: Sanquer - first_name: Silvano full_name: De Franceschi, Silvano last_name: De Franceschi citation: ama: Mongillo M, Spathis P, Katsaros G, Gentile P, Sanquer M, De Franceschi S. Joule-assisted silicidation for short-channel silicon nanowire devices. ACS Nano. 2011;5(9):7117-7123. doi:10.1021/nn202524j apa: Mongillo, M., Spathis, P., Katsaros, G., Gentile, P., Sanquer, M., & De Franceschi, S. (2011). Joule-assisted silicidation for short-channel silicon nanowire devices. ACS Nano. American Chemical Society. https://doi.org/10.1021/nn202524j chicago: Mongillo, Massimo, Panayotis Spathis, Georgios Katsaros, Pascal Gentile, Marc Sanquer, and Silvano De Franceschi. “Joule-Assisted Silicidation for Short-Channel Silicon Nanowire Devices.” ACS Nano. American Chemical Society, 2011. https://doi.org/10.1021/nn202524j. ieee: M. Mongillo, P. Spathis, G. Katsaros, P. Gentile, M. Sanquer, and S. De Franceschi, “Joule-assisted silicidation for short-channel silicon nanowire devices,” ACS Nano, vol. 5, no. 9. American Chemical Society, pp. 7117–7123, 2011. ista: Mongillo M, Spathis P, Katsaros G, Gentile P, Sanquer M, De Franceschi S. 2011. Joule-assisted silicidation for short-channel silicon nanowire devices. ACS Nano. 5(9), 7117–7123. mla: Mongillo, Massimo, et al. “Joule-Assisted Silicidation for Short-Channel Silicon Nanowire Devices.” ACS Nano, vol. 5, no. 9, American Chemical Society, 2011, pp. 7117–23, doi:10.1021/nn202524j. short: M. Mongillo, P. Spathis, G. Katsaros, P. Gentile, M. Sanquer, S. De Franceschi, ACS Nano 5 (2011) 7117–7123. date_created: 2018-12-11T11:53:50Z date_published: 2011-09-27T00:00:00Z date_updated: 2021-01-12T06:52:59Z day: '27' doi: 10.1021/nn202524j extern: '1' external_id: arxiv: - '1110.5668' intvolume: ' 5' issue: '9' language: - iso: eng main_file_link: - open_access: '1' url: http://arxiv.org/abs/1110.5668 month: '09' oa: 1 oa_version: Preprint page: 7117 - 7123 publication: ACS Nano publication_status: published publisher: American Chemical Society publist_id: '5370' quality_controlled: '1' status: public title: Joule-assisted silicidation for short-channel silicon nanowire devices type: journal_article user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87 volume: 5 year: '2011' ...