---
_id: '6140'
abstract:
- lang: eng
text: 'Genome sequence comparisons have highlighted many novel gene families that
are conserved across animal phyla but whose biological function is unknown. Here,
we functionally characterize a member of one such family, the macoilins. Macoilins
are characterized by several highly conserved predicted transmembrane domains
towards the N-terminus and by coiled-coil regions C-terminally. They are found
throughout Eumetazoa but not in other organisms. Mutants for the single Caenorhabditis
elegans macoilin, maco-1, exhibit a constellation of behavioral phenotypes, including
defects in aggregation, O2 responses, and swimming. MACO-1 protein is expressed
broadly and specifically in the nervous system and localizes to the rough endoplasmic
reticulum; it is excluded from dendrites and axons. Apart from subtle synapse
defects, nervous system development appears wild-type in maco-1 mutants. However,
maco-1 animals are resistant to the cholinesterase inhibitor aldicarb and sensitive
to levamisole, suggesting pre-synaptic defects. Using in vivo imaging, we show
that macoilin is required to evoke Ca2+ transients, at least in some neurons:
in maco-1 mutants the O2-sensing neuron PQR is unable to generate a Ca2+ response
to a rise in O2. By genetically disrupting neurotransmission, we show that pre-synaptic
input is not necessary for PQR to respond to O2, indicating that the response
is mediated by cell-intrinsic sensory transduction and amplification. Disrupting
the sodium leak channels NCA-1/NCA-2, or the N-,P/Q,R-type voltage-gated Ca2+
channels, also fails to disrupt Ca2+ responses in the PQR cell body to O2 stimuli.
By contrast, mutations in egl-19, which encodes the only Caenorhabditis elegans
L-type voltage-gated Ca2+ channel α1 subunit, recapitulate the Ca2+ response defect
we see in maco-1 mutants, although we do not see defects in localization of EGL-19.
Together, our data suggest that macoilin acts in the ER to regulate assembly or
traffic of ion channels or ion channel regulators.'
article_number: e1001341
author:
- first_name: Fausto
full_name: Arellano-Carbajal, Fausto
last_name: Arellano-Carbajal
- first_name: Luis
full_name: Briseño-Roa, Luis
last_name: Briseño-Roa
- first_name: Africa
full_name: Couto, Africa
last_name: Couto
- first_name: Benny H. H.
full_name: Cheung, Benny H. H.
last_name: Cheung
- first_name: Michel
full_name: Labouesse, Michel
last_name: Labouesse
- first_name: Mario
full_name: de Bono, Mario
id: 4E3FF80E-F248-11E8-B48F-1D18A9856A87
last_name: de Bono
orcid: 0000-0001-8347-0443
citation:
ama: Arellano-Carbajal F, Briseño-Roa L, Couto A, Cheung BHH, Labouesse M, de Bono
M. Macoilin, a conserved nervous system–specific ER membrane protein that regulates
neuronal excitability. PLoS Genetics. 2011;7(3). doi:10.1371/journal.pgen.1001341
apa: Arellano-Carbajal, F., Briseño-Roa, L., Couto, A., Cheung, B. H. H., Labouesse,
M., & de Bono, M. (2011). Macoilin, a conserved nervous system–specific ER
membrane protein that regulates neuronal excitability. PLoS Genetics. Public
Library of Science. https://doi.org/10.1371/journal.pgen.1001341
chicago: Arellano-Carbajal, Fausto, Luis Briseño-Roa, Africa Couto, Benny H. H.
Cheung, Michel Labouesse, and Mario de Bono. “Macoilin, a Conserved Nervous System–Specific
ER Membrane Protein That Regulates Neuronal Excitability.” PLoS Genetics.
Public Library of Science, 2011. https://doi.org/10.1371/journal.pgen.1001341.
ieee: F. Arellano-Carbajal, L. Briseño-Roa, A. Couto, B. H. H. Cheung, M. Labouesse,
and M. de Bono, “Macoilin, a conserved nervous system–specific ER membrane protein
that regulates neuronal excitability,” PLoS Genetics, vol. 7, no. 3. Public
Library of Science, 2011.
ista: Arellano-Carbajal F, Briseño-Roa L, Couto A, Cheung BHH, Labouesse M, de Bono
M. 2011. Macoilin, a conserved nervous system–specific ER membrane protein that
regulates neuronal excitability. PLoS Genetics. 7(3), e1001341.
mla: Arellano-Carbajal, Fausto, et al. “Macoilin, a Conserved Nervous System–Specific
ER Membrane Protein That Regulates Neuronal Excitability.” PLoS Genetics,
vol. 7, no. 3, e1001341, Public Library of Science, 2011, doi:10.1371/journal.pgen.1001341.
short: F. Arellano-Carbajal, L. Briseño-Roa, A. Couto, B.H.H. Cheung, M. Labouesse,
M. de Bono, PLoS Genetics 7 (2011).
date_created: 2019-03-20T15:08:23Z
date_published: 2011-03-17T00:00:00Z
date_updated: 2021-01-12T08:06:19Z
day: '17'
ddc:
- '570'
doi: 10.1371/journal.pgen.1001341
extern: '1'
external_id:
pmid:
- '21437263'
file:
- access_level: open_access
checksum: c609b2ce616d7dafbb617ec5d022f1ea
content_type: application/pdf
creator: kschuh
date_created: 2019-03-20T15:18:11Z
date_updated: 2020-07-14T12:47:20Z
file_id: '6141'
file_name: 2011_PLOS_Arellano-Carbajal.PDF
file_size: 5625063
relation: main_file
file_date_updated: 2020-07-14T12:47:20Z
has_accepted_license: '1'
intvolume: ' 7'
issue: '3'
language:
- iso: eng
month: '03'
oa: 1
oa_version: Published Version
pmid: 1
publication: PLoS Genetics
publication_identifier:
issn:
- 1553-7404
publication_status: published
publisher: Public Library of Science
quality_controlled: '1'
status: public
title: Macoilin, a conserved nervous system–specific ER membrane protein that regulates
neuronal excitability
tmp:
image: /images/cc_by.png
legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
short: CC BY (4.0)
type: journal_article
user_id: 3E5EF7F0-F248-11E8-B48F-1D18A9856A87
volume: 7
year: '2011'
...
---
_id: '6137'
abstract:
- lang: eng
text: Variation in food quality and abundance requires animals to decide whether
to stay on a poor food patch or leave in search of better food. An important question
in behavioral ecology asks when is it optimal for an animal to leave a food patch
it is depleting. Although optimal foraging is central to evolutionary success,
the neural and molecular mechanisms underlying it are poorly understood. Here
we investigate the neuronal basis for adaptive food-leaving behavior in response
to resource depletion in Caenorhabditis elegans, and identify several of the signaling
pathways involved. The ASE neurons, previously implicated in salt chemoattraction,
promote food-leaving behavior via a cGMP pathway as food becomes limited. High
ambient O2 promotes food-leaving via the O2-sensing neurons AQR, PQR, and URX.
Ectopic activation of these neurons using channelrhodopsin is sufficient to induce
high food-leaving behavior. In contrast, the neuropeptide receptor NPR-1, which
regulates social behavior on food, acts in the ASE neurons, the nociceptive ASH
neurons, and in the RMG interneuron to repress food-leaving. Finally, we show
that neuroendocrine signaling by TGF-β/DAF-7 and neuronal insulin signaling are
necessary for adaptive food-leaving behavior. We suggest that animals integrate
information about their nutritional state with ambient oxygen and gustatory stimuli
to formulate optimal foraging strategies.
author:
- first_name: K.
full_name: Milward, K.
last_name: Milward
- first_name: K. E.
full_name: Busch, K. E.
last_name: Busch
- first_name: R. J.
full_name: Murphy, R. J.
last_name: Murphy
- first_name: Mario
full_name: de Bono, Mario
id: 4E3FF80E-F248-11E8-B48F-1D18A9856A87
last_name: de Bono
orcid: 0000-0001-8347-0443
- first_name: B.
full_name: Olofsson, B.
last_name: Olofsson
citation:
ama: Milward K, Busch KE, Murphy RJ, de Bono M, Olofsson B. Neuronal and molecular
substrates for optimal foraging in Caenorhabditis elegans. Proceedings of the
National Academy of Sciences. 2011;108(51):20672-20677. doi:10.1073/pnas.1106134109
apa: Milward, K., Busch, K. E., Murphy, R. J., de Bono, M., & Olofsson, B. (2011).
Neuronal and molecular substrates for optimal foraging in Caenorhabditis elegans.
Proceedings of the National Academy of Sciences. National Academy of Sciences.
https://doi.org/10.1073/pnas.1106134109
chicago: Milward, K., K. E. Busch, R. J. Murphy, Mario de Bono, and B. Olofsson.
“Neuronal and Molecular Substrates for Optimal Foraging in Caenorhabditis Elegans.”
Proceedings of the National Academy of Sciences. National Academy of Sciences,
2011. https://doi.org/10.1073/pnas.1106134109.
ieee: K. Milward, K. E. Busch, R. J. Murphy, M. de Bono, and B. Olofsson, “Neuronal
and molecular substrates for optimal foraging in Caenorhabditis elegans,” Proceedings
of the National Academy of Sciences, vol. 108, no. 51. National Academy of
Sciences, pp. 20672–20677, 2011.
ista: Milward K, Busch KE, Murphy RJ, de Bono M, Olofsson B. 2011. Neuronal and
molecular substrates for optimal foraging in Caenorhabditis elegans. Proceedings
of the National Academy of Sciences. 108(51), 20672–20677.
mla: Milward, K., et al. “Neuronal and Molecular Substrates for Optimal Foraging
in Caenorhabditis Elegans.” Proceedings of the National Academy of Sciences,
vol. 108, no. 51, National Academy of Sciences, 2011, pp. 20672–77, doi:10.1073/pnas.1106134109.
short: K. Milward, K.E. Busch, R.J. Murphy, M. de Bono, B. Olofsson, Proceedings
of the National Academy of Sciences 108 (2011) 20672–20677.
date_created: 2019-03-20T14:30:06Z
date_published: 2011-12-20T00:00:00Z
date_updated: 2021-01-12T08:06:18Z
day: '20'
doi: 10.1073/pnas.1106134109
extern: '1'
external_id:
pmid:
- '22135454'
intvolume: ' 108'
issue: '51'
language:
- iso: eng
main_file_link:
- open_access: '1'
url: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3251049/
month: '12'
oa: 1
oa_version: Submitted Version
page: 20672-20677
pmid: 1
publication: Proceedings of the National Academy of Sciences
publication_identifier:
issn:
- 0027-8424
- 1091-6490
publication_status: published
publisher: National Academy of Sciences
quality_controlled: '1'
status: public
title: Neuronal and molecular substrates for optimal foraging in Caenorhabditis elegans
type: journal_article
user_id: 3E5EF7F0-F248-11E8-B48F-1D18A9856A87
volume: 108
year: '2011'
...
---
_id: '6138'
author:
- first_name: Andrew Jonathan
full_name: Bretscher, Andrew Jonathan
last_name: Bretscher
- first_name: Eiji
full_name: Kodama-Namba, Eiji
last_name: Kodama-Namba
- first_name: Karl Emanuel
full_name: Busch, Karl Emanuel
last_name: Busch
- first_name: Robin Joseph
full_name: Murphy, Robin Joseph
last_name: Murphy
- first_name: Zoltan
full_name: Soltesz, Zoltan
last_name: Soltesz
- first_name: Patrick
full_name: Laurent, Patrick
last_name: Laurent
- first_name: Mario
full_name: de Bono, Mario
id: 4E3FF80E-F248-11E8-B48F-1D18A9856A87
last_name: de Bono
orcid: 0000-0001-8347-0443
citation:
ama: Bretscher AJ, Kodama-Namba E, Busch KE, et al. Temperature, oxygen, and salt-sensing
neurons in C. elegans are carbon dioxide sensors that control avoidance behavior.
Neuron. 2011;69(6):1099-1113. doi:10.1016/j.neuron.2011.02.023
apa: Bretscher, A. J., Kodama-Namba, E., Busch, K. E., Murphy, R. J., Soltesz, Z.,
Laurent, P., & de Bono, M. (2011). Temperature, oxygen, and salt-sensing neurons
in C. elegans are carbon dioxide sensors that control avoidance behavior. Neuron.
Elsevier BV. https://doi.org/10.1016/j.neuron.2011.02.023
chicago: Bretscher, Andrew Jonathan, Eiji Kodama-Namba, Karl Emanuel Busch, Robin Joseph
Murphy, Zoltan Soltesz, Patrick Laurent, and Mario de Bono. “Temperature, Oxygen,
and Salt-Sensing Neurons in C. Elegans Are Carbon Dioxide Sensors That Control
Avoidance Behavior.” Neuron. Elsevier BV, 2011. https://doi.org/10.1016/j.neuron.2011.02.023.
ieee: A. J. Bretscher et al., “Temperature, oxygen, and salt-sensing neurons
in C. elegans are carbon dioxide sensors that control avoidance behavior,” Neuron,
vol. 69, no. 6. Elsevier BV, pp. 1099–1113, 2011.
ista: Bretscher AJ, Kodama-Namba E, Busch KE, Murphy RJ, Soltesz Z, Laurent P, de
Bono M. 2011. Temperature, oxygen, and salt-sensing neurons in C. elegans are
carbon dioxide sensors that control avoidance behavior. Neuron. 69(6), 1099–1113.
mla: Bretscher, Andrew Jonathan, et al. “Temperature, Oxygen, and Salt-Sensing Neurons
in C. Elegans Are Carbon Dioxide Sensors That Control Avoidance Behavior.” Neuron,
vol. 69, no. 6, Elsevier BV, 2011, pp. 1099–113, doi:10.1016/j.neuron.2011.02.023.
short: A.J. Bretscher, E. Kodama-Namba, K.E. Busch, R.J. Murphy, Z. Soltesz, P.
Laurent, M. de Bono, Neuron 69 (2011) 1099–1113.
date_created: 2019-03-20T15:01:41Z
date_published: 2011-03-24T00:00:00Z
date_updated: 2021-01-12T08:06:18Z
day: '24'
ddc:
- '570'
doi: 10.1016/j.neuron.2011.02.023
extern: '1'
external_id:
pmid:
- '21435556'
file:
- access_level: open_access
checksum: 547cffd123f4c508ae927c9244b8f92a
content_type: application/pdf
creator: kschuh
date_created: 2019-03-20T15:06:32Z
date_updated: 2020-07-14T12:47:20Z
file_id: '6139'
file_name: 2011_Cell_Bretscher.pdf
file_size: 2448332
relation: main_file
file_date_updated: 2020-07-14T12:47:20Z
has_accepted_license: '1'
intvolume: ' 69'
issue: '6'
language:
- iso: eng
month: '03'
oa: 1
oa_version: Published Version
page: 1099-1113
pmid: 1
publication: Neuron
publication_identifier:
issn:
- 0896-6273
publication_status: published
publisher: Elsevier BV
quality_controlled: '1'
status: public
title: Temperature, oxygen, and salt-sensing neurons in C. elegans are carbon dioxide
sensors that control avoidance behavior
tmp:
image: /images/cc_by.png
legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
short: CC BY (4.0)
type: journal_article
user_id: 3E5EF7F0-F248-11E8-B48F-1D18A9856A87
volume: 69
year: '2011'
...
---
_id: '6298'
abstract:
- lang: eng
text: Tumor necrosis factor-stimulated gene-6 (TSG-6) is a hyalu-ronan (HA)-binding
protein that plays important roles ininflammation and ovulation. TSG-6-mediated
cross-linking ofHA has been proposed as a functional mechanism (e.g.for regu-lating
leukocyte adhesion), but direct evidence for cross-linkingis lacking, and we know
very little about its impact on HA ultra-structure. Here we used films of polymeric
and oligomeric HAchains, end-grafted to a solid support, and a combination ofsurface-sensitive
biophysical techniques to quantify the bindingof TSG-6 into HA films and to correlate
binding to morpholog-ical changes. We find that full-length TSG-6 binds with pro-nounced
positive cooperativity and demonstrate that it cancross-link HA at physiologically
relevant concentrations. Ourdata indicate that cooperative binding of full-length
TSG-6arises from HA-induced protein oligomerization and that theTSG-6 oligomers
act as cross-linkers. In contrast, the HA-bind-ing domain of TSG-6 (the Link module)
alone binds withoutpositive cooperativity and weaker than the full-length protein.Both
the Link module and full-length TSG-6 condensed andrigidified HA films, and the
degree of condensation scaled withthe affinity between the TSG-6 constructs and
HA. We proposethat condensation is the result of protein-mediated HA cross-linking.
Our findings firmly establish that TSG-6 is a potent HAcross-linking agent and
might hence have important implica-tions for the mechanistic understanding of
the biological func-tion of TSG-6 (e.g.in inflammation).
author:
- first_name: Natalia
full_name: Baranova, Natalia
id: 38661662-F248-11E8-B48F-1D18A9856A87
last_name: Baranova
orcid: 0000-0002-3086-9124
- first_name: Erik
full_name: Nilebäck, Erik
last_name: Nilebäck
- first_name: F. Michael
full_name: Haller, F. Michael
last_name: Haller
- first_name: David C.
full_name: Briggs, David C.
last_name: Briggs
- first_name: Sofia
full_name: Svedhem, Sofia
last_name: Svedhem
- first_name: Anthony J.
full_name: Day, Anthony J.
last_name: Day
- first_name: Ralf P.
full_name: Richter, Ralf P.
last_name: Richter
citation:
ama: Baranova NS, Nilebäck E, Haller FM, et al. The inflammation-associated protein
TSG-6 cross-links hyaluronan via hyaluronan-induced TSG-6 oligomers. Journal
of Biological Chemistry. 2011;286(29):25675-25686. doi:10.1074/jbc.m111.247395
apa: Baranova, N. S., Nilebäck, E., Haller, F. M., Briggs, D. C., Svedhem, S., Day,
A. J., & Richter, R. P. (2011). The inflammation-associated protein TSG-6
cross-links hyaluronan via hyaluronan-induced TSG-6 oligomers. Journal of Biological
Chemistry. American Society for Biochemistry & Molecular Biology. https://doi.org/10.1074/jbc.m111.247395
chicago: Baranova, Natalia S., Erik Nilebäck, F. Michael Haller, David C. Briggs,
Sofia Svedhem, Anthony J. Day, and Ralf P. Richter. “The Inflammation-Associated
Protein TSG-6 Cross-Links Hyaluronan via Hyaluronan-Induced TSG-6 Oligomers.”
Journal of Biological Chemistry. American Society for Biochemistry &
Molecular Biology, 2011. https://doi.org/10.1074/jbc.m111.247395.
ieee: N. S. Baranova et al., “The inflammation-associated protein TSG-6 cross-links
hyaluronan via hyaluronan-induced TSG-6 oligomers,” Journal of Biological Chemistry,
vol. 286, no. 29. American Society for Biochemistry & Molecular Biology, pp.
25675–25686, 2011.
ista: Baranova NS, Nilebäck E, Haller FM, Briggs DC, Svedhem S, Day AJ, Richter
RP. 2011. The inflammation-associated protein TSG-6 cross-links hyaluronan via
hyaluronan-induced TSG-6 oligomers. Journal of Biological Chemistry. 286(29),
25675–25686.
mla: Baranova, Natalia S., et al. “The Inflammation-Associated Protein TSG-6 Cross-Links
Hyaluronan via Hyaluronan-Induced TSG-6 Oligomers.” Journal of Biological Chemistry,
vol. 286, no. 29, American Society for Biochemistry & Molecular Biology, 2011,
pp. 25675–86, doi:10.1074/jbc.m111.247395.
short: N.S. Baranova, E. Nilebäck, F.M. Haller, D.C. Briggs, S. Svedhem, A.J. Day,
R.P. Richter, Journal of Biological Chemistry 286 (2011) 25675–25686.
date_created: 2019-04-11T20:57:43Z
date_published: 2011-07-22T00:00:00Z
date_updated: 2021-01-12T08:06:58Z
day: '22'
doi: 10.1074/jbc.m111.247395
extern: '1'
intvolume: ' 286'
issue: '29'
language:
- iso: eng
main_file_link:
- open_access: '1'
url: http://www.jbc.org/content/286/29/25675.full.pdf
month: '07'
oa: 1
oa_version: Published Version
page: 25675-25686
publication: Journal of Biological Chemistry
publication_identifier:
issn:
- 0021-9258
- 1083-351X
publication_status: published
publisher: American Society for Biochemistry & Molecular Biology
quality_controlled: '1'
status: public
title: The inflammation-associated protein TSG-6 cross-links hyaluronan via hyaluronan-induced
TSG-6 oligomers
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 286
year: '2011'
...
---
_id: '6496'
abstract:
- lang: eng
text: We report the switching behavior of the full bacterial flagellum system that
includes the filament and the motor in wild-type Escherichia coli cells. In sorting
the motor behavior by the clockwise bias, we find that the distributions of the
clockwise (CW) and counterclockwise (CCW) intervals are either exponential or
nonexponential with long tails. At low bias, CW intervals are exponentially distributed
and CCW intervals exhibit long tails. At intermediate CW bias (0.5) both CW and
CCW intervals are mainly exponentially distributed. A simple model suggests that
these two distinct switching behaviors are governed by the presence of signaling
noise within the chemotaxis network. Low noise yields exponentially distributed
intervals, whereas large noise yields nonexponential behavior with long tails.
These drastically different motor statistics may play a role in optimizing bacterial
behavior for a wide range of environmental conditions.
article_processing_charge: No
author:
- first_name: Heungwon
full_name: Park, Heungwon
last_name: Park
- first_name: Panos
full_name: Oikonomou, Panos
last_name: Oikonomou
- first_name: Calin C
full_name: Guet, Calin C
id: 47F8433E-F248-11E8-B48F-1D18A9856A87
last_name: Guet
orcid: 0000-0001-6220-2052
- first_name: Philippe
full_name: Cluzel, Philippe
last_name: Cluzel
citation:
ama: Park H, Oikonomou P, Guet CC, Cluzel P. Noise underlies switching behavior
of the bacterial flagellum. Biophysical Journal. 2011;101(10):2336-2340.
doi:10.1016/j.bpj.2011.09.040
apa: Park, H., Oikonomou, P., Guet, C. C., & Cluzel, P. (2011). Noise underlies
switching behavior of the bacterial flagellum. Biophysical Journal. Elsevier.
https://doi.org/10.1016/j.bpj.2011.09.040
chicago: Park, Heungwon, Panos Oikonomou, Calin C Guet, and Philippe Cluzel. “Noise
Underlies Switching Behavior of the Bacterial Flagellum.” Biophysical Journal.
Elsevier, 2011. https://doi.org/10.1016/j.bpj.2011.09.040.
ieee: H. Park, P. Oikonomou, C. C. Guet, and P. Cluzel, “Noise underlies switching
behavior of the bacterial flagellum,” Biophysical Journal, vol. 101, no.
10. Elsevier, pp. 2336–2340, 2011.
ista: Park H, Oikonomou P, Guet CC, Cluzel P. 2011. Noise underlies switching behavior
of the bacterial flagellum. Biophysical Journal. 101(10), 2336–2340.
mla: Park, Heungwon, et al. “Noise Underlies Switching Behavior of the Bacterial
Flagellum.” Biophysical Journal, vol. 101, no. 10, Elsevier, 2011, pp.
2336–40, doi:10.1016/j.bpj.2011.09.040.
short: H. Park, P. Oikonomou, C.C. Guet, P. Cluzel, Biophysical Journal 101 (2011)
2336–2340.
date_created: 2019-05-28T11:54:29Z
date_published: 2011-11-16T00:00:00Z
date_updated: 2021-04-16T11:54:49Z
day: '16'
department:
- _id: CaGu
doi: 10.1016/j.bpj.2011.09.040
external_id:
pmid:
- '22098731'
intvolume: ' 101'
issue: '10'
language:
- iso: eng
main_file_link:
- open_access: '1'
url: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3218319/
month: '11'
oa: 1
oa_version: Published Version
page: 2336-2340
pmid: 1
publication: Biophysical Journal
publication_identifier:
issn:
- 0006-3495
publication_status: published
publisher: Elsevier
quality_controlled: '1'
scopus_import: '1'
status: public
title: Noise underlies switching behavior of the bacterial flagellum
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 101
year: '2011'
...
---
_id: '6749'
abstract:
- lang: eng
text: This article refers to algorithms based on finite difference schemes for computing
mean and affine curvature evolutions of digital images, introduced by Alvarez
and Morel [L. Alvarez, J.M. Morel, “Formalization and computational aspects of
image analysis”, Acta Numerica, pp. 159, 1994]. We discuss consistency, stability
and convergence. Our analysis focuses on some possible choices of the parameters,
choices that generate multiple variants in the implementations. Meaningful visual
examples on how the algorithms actually work are provided.
author:
- first_name: Marco
full_name: Mondelli, Marco
id: 27EB676C-8706-11E9-9510-7717E6697425
last_name: Mondelli
orcid: 0000-0002-3242-7020
- first_name: Adina
full_name: Ciomaga, Adina
last_name: Ciomaga
citation:
ama: Mondelli M, Ciomaga A. Finite difference schemes for MCM and AMSS. Image
Processing On Line. 2011;1:127-177. doi:10.5201/ipol.2011.cm_fds
apa: Mondelli, M., & Ciomaga, A. (2011). Finite difference schemes for MCM and
AMSS. Image Processing On Line. IPOL Image Processing On Line. https://doi.org/10.5201/ipol.2011.cm_fds
chicago: Mondelli, Marco, and Adina Ciomaga. “Finite Difference Schemes for MCM
and AMSS.” Image Processing On Line. IPOL Image Processing On Line, 2011.
https://doi.org/10.5201/ipol.2011.cm_fds.
ieee: M. Mondelli and A. Ciomaga, “Finite difference schemes for MCM and AMSS,”
Image Processing On Line, vol. 1. IPOL Image Processing On Line, pp. 127–177,
2011.
ista: Mondelli M, Ciomaga A. 2011. Finite difference schemes for MCM and AMSS. Image
Processing On Line. 1, 127–177.
mla: Mondelli, Marco, and Adina Ciomaga. “Finite Difference Schemes for MCM and
AMSS.” Image Processing On Line, vol. 1, IPOL Image Processing On Line,
2011, pp. 127–77, doi:10.5201/ipol.2011.cm_fds.
short: M. Mondelli, A. Ciomaga, Image Processing On Line 1 (2011) 127–177.
date_created: 2019-07-31T09:44:24Z
date_published: 2011-09-13T00:00:00Z
date_updated: 2021-01-12T08:08:50Z
day: '13'
ddc:
- '000'
doi: 10.5201/ipol.2011.cm_fds
extern: '1'
file:
- access_level: open_access
checksum: 910710811224c633202791e0c217d05d
content_type: application/pdf
creator: dernst
date_created: 2019-08-01T06:34:21Z
date_updated: 2020-07-14T12:47:39Z
file_id: '6751'
file_name: 2011_IPOL_Mondelli.pdf
file_size: 2793903
relation: main_file
file_date_updated: 2020-07-14T12:47:39Z
has_accepted_license: '1'
intvolume: ' 1'
language:
- iso: eng
license: https://creativecommons.org/licenses/by-nc-sa/4.0/
month: '09'
oa: 1
oa_version: Published Version
page: 127-177
publication: Image Processing On Line
publication_identifier:
issn:
- 2105-1232
publication_status: published
publisher: IPOL Image Processing On Line
quality_controlled: '1'
status: public
title: Finite difference schemes for MCM and AMSS
tmp:
image: /images/cc_by_nc_sa.png
legal_code_url: https://creativecommons.org/licenses/by-nc-sa/4.0/legalcode
name: Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International (CC
BY-NC-SA 4.0)
short: CC BY-NC-SA (4.0)
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 1
year: '2011'
...
---
_id: '6767'
abstract:
- lang: eng
text: "In the present paper we give a thorough analysis of two finite difference
schemes for the Mean Curvature Motion and its affine variant, the Affine Morphological
Scale Space, schemes introduced in the Image Processing framework. This analysis
brings in a series of parameters that allow us to compute an accurate discrete
evolution of curvature motions.\r\nThe choice of these parameters is based on
intrinsic geometric properties of the evolution equations for linear, radial and
elliptical functions. In the last part we present several examples, underlining
the main advantages of the algorithms (the removal of pixelization effects and
JPEG artifacts) as well as their major drawbacks (absence of contrast invariance
and grid dependence). A detailed explanatory report, the ANSI C implementations
and an on-line demo can be found at http://www.ipol.im/."
author:
- first_name: Marco
full_name: Mondelli, Marco
id: 27EB676C-8706-11E9-9510-7717E6697425
last_name: Mondelli
orcid: 0000-0002-3242-7020
- first_name: Adina
full_name: Ciomaga, Adina
last_name: Ciomaga
citation:
ama: 'Mondelli M, Ciomaga A. On finite difference schemes for curvature motions.
In: Proceedings of the International Student Conference on Pure and Applied
Mathematics. Editura Universitãtii „Alexandru Ioan Cuza” Iasi; 2011:137-156.
doi:10.13140/2.1.1862.4646'
apa: 'Mondelli, M., & Ciomaga, A. (2011). On finite difference schemes for curvature
motions. In Proceedings of the International Student Conference on Pure and
Applied Mathematics (pp. 137–156). Iasi, Romania: Editura Universitãtii „Alexandru
Ioan Cuza” Iasi. https://doi.org/10.13140/2.1.1862.4646'
chicago: Mondelli, Marco, and Adina Ciomaga. “On Finite Difference Schemes for Curvature
Motions.” In Proceedings of the International Student Conference on Pure and
Applied Mathematics, 137–56. Editura Universitãtii „Alexandru Ioan Cuza” Iasi,
2011. https://doi.org/10.13140/2.1.1862.4646.
ieee: M. Mondelli and A. Ciomaga, “On finite difference schemes for curvature motions,”
in Proceedings of the International Student Conference on Pure and Applied
Mathematics, Iasi, Romania, 2011, pp. 137–156.
ista: 'Mondelli M, Ciomaga A. 2011. On finite difference schemes for curvature motions.
Proceedings of the International Student Conference on Pure and Applied Mathematics.
ISCOPAM: International Student Conference on Pure and Applied Mathematics, 137–156.'
mla: Mondelli, Marco, and Adina Ciomaga. “On Finite Difference Schemes for Curvature
Motions.” Proceedings of the International Student Conference on Pure and Applied
Mathematics, Editura Universitãtii „Alexandru Ioan Cuza” Iasi, 2011, pp. 137–56,
doi:10.13140/2.1.1862.4646.
short: M. Mondelli, A. Ciomaga, in:, Proceedings of the International Student Conference
on Pure and Applied Mathematics, Editura Universitãtii „Alexandru Ioan Cuza” Iasi,
2011, pp. 137–156.
conference:
end_date: 2010-07-16
location: Iasi, Romania
name: 'ISCOPAM: International Student Conference on Pure and Applied Mathematics'
start_date: 2010-07-12
date_created: 2019-08-05T12:20:58Z
date_published: 2011-01-01T00:00:00Z
date_updated: 2021-01-12T08:08:56Z
day: '01'
doi: 10.13140/2.1.1862.4646
extern: '1'
language:
- iso: eng
month: '01'
oa_version: None
page: 137-156
publication: Proceedings of the International Student Conference on Pure and Applied
Mathematics
publication_identifier:
isbn:
- 978-973-703-602-5
publication_status: published
publisher: Editura Universitãtii „Alexandru Ioan Cuza” Iasi
quality_controlled: '1'
status: public
title: On finite difference schemes for curvature motions
type: conference
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
year: '2011'
...
---
_id: '7076'
abstract:
- lang: eng
text: Iron is a ubiquitous impurity in metamict (radiation-damaged and partially
amorphized) materials such as titanite (CaSiTiO5). Using 57Fe Mössbauer spectroscopy
we find that iron in metamict titanite is partitioned between amorphous and crystalline
regions based on valence. Trivalent iron exists in the crystalline titanite matrix
whereas divalent iron exists almost exclusively in radiation-amorphized regions.
We find that the relative abundances of the oxidation states correlate with the
volume fraction of amorphous and crystalline regions. Our data also show that
oxidation of iron proceeds along with the recrystallization of the amorphized
regions. Recrystallization is confirmed to occur over the range 700 °C < T < 925 °C,
and no further structural changes are observed at higher temperatures. It is surprising
that our Mössbauer measurements show divalent iron to be surrounded by titanite
with a high degree of short-range structural order in the amorphized regions.
This observation is fundamentally different from other metamict materials such
as zircon (ZrSiO4), where amorphized regions show no short-range order.
article_number: '105402'
article_processing_charge: No
article_type: original
author:
- first_name: E K H
full_name: Salje, E K H
last_name: Salje
- first_name: D J
full_name: Safarik, D J
last_name: Safarik
- first_name: R D
full_name: Taylor, R D
last_name: Taylor
- first_name: M P
full_name: Pasternak, M P
last_name: Pasternak
- first_name: Kimberly A
full_name: Modic, Kimberly A
id: 13C26AC0-EB69-11E9-87C6-5F3BE6697425
last_name: Modic
orcid: 0000-0001-9760-3147
- first_name: L A
full_name: Groat, L A
last_name: Groat
- first_name: J C
full_name: Lashley, J C
last_name: Lashley
citation:
ama: 'Salje EKH, Safarik DJ, Taylor RD, et al. Determination of iron sites and the
amount of amorphization in radiation-damaged titanite (CaSiTiO5). Journal of
Physics: Condensed Matter. 2011;23(10). doi:10.1088/0953-8984/23/10/105402'
apa: 'Salje, E. K. H., Safarik, D. J., Taylor, R. D., Pasternak, M. P., Modic, K.
A., Groat, L. A., & Lashley, J. C. (2011). Determination of iron sites and
the amount of amorphization in radiation-damaged titanite (CaSiTiO5). Journal
of Physics: Condensed Matter. IOP Publishing. https://doi.org/10.1088/0953-8984/23/10/105402'
chicago: 'Salje, E K H, D J Safarik, R D Taylor, M P Pasternak, Kimberly A Modic,
L A Groat, and J C Lashley. “Determination of Iron Sites and the Amount of Amorphization
in Radiation-Damaged Titanite (CaSiTiO5).” Journal of Physics: Condensed Matter.
IOP Publishing, 2011. https://doi.org/10.1088/0953-8984/23/10/105402.'
ieee: 'E. K. H. Salje et al., “Determination of iron sites and the amount
of amorphization in radiation-damaged titanite (CaSiTiO5),” Journal of Physics:
Condensed Matter, vol. 23, no. 10. IOP Publishing, 2011.'
ista: 'Salje EKH, Safarik DJ, Taylor RD, Pasternak MP, Modic KA, Groat LA, Lashley
JC. 2011. Determination of iron sites and the amount of amorphization in radiation-damaged
titanite (CaSiTiO5). Journal of Physics: Condensed Matter. 23(10), 105402.'
mla: 'Salje, E. K. H., et al. “Determination of Iron Sites and the Amount of Amorphization
in Radiation-Damaged Titanite (CaSiTiO5).” Journal of Physics: Condensed Matter,
vol. 23, no. 10, 105402, IOP Publishing, 2011, doi:10.1088/0953-8984/23/10/105402.'
short: 'E.K.H. Salje, D.J. Safarik, R.D. Taylor, M.P. Pasternak, K.A. Modic, L.A.
Groat, J.C. Lashley, Journal of Physics: Condensed Matter 23 (2011).'
date_created: 2019-11-19T13:39:30Z
date_published: 2011-02-21T00:00:00Z
date_updated: 2021-01-12T08:11:43Z
day: '21'
doi: 10.1088/0953-8984/23/10/105402
extern: '1'
intvolume: ' 23'
issue: '10'
language:
- iso: eng
month: '02'
oa_version: None
publication: 'Journal of Physics: Condensed Matter'
publication_identifier:
issn:
- 0953-8984
- 1361-648X
publication_status: published
publisher: IOP Publishing
quality_controlled: '1'
status: public
title: Determination of iron sites and the amount of amorphization in radiation-damaged
titanite (CaSiTiO5)
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 23
year: '2011'
...
---
_id: '7077'
abstract:
- lang: eng
text: Pb, Te, Ag and Se, when reacted in a 1:1:x:1 (x = 1.9, 2.0, 2.01) molar ratio,
form a two phase composite which consists of a phase which crystallizes in the
fcc cubic PbSe structure and a phase that crystallizes in the Ag2Te structure.
In this article, we demonstrate that by varying the Ag concentration, we can manipulate
which variant of the Ag2Te structure stabilizes at room temperature (monoclinic
α-Ag2Te or cubic β-Ag1.9Te) and can consequently manipulate the electrical and
thermal transport behavior of the composite and hence the thermoelectric performance.
Additionally, we show that Cu-doping results in an overall improvement in thermoelectric
performance. Our results suggest that formation of composites is a viable path
for achieving a phonon-glass-electron-crystal (PGEC) alloy.
article_processing_charge: No
article_type: original
author:
- first_name: J.
full_name: Capps, J.
last_name: Capps
- first_name: B.
full_name: Ma, B.
last_name: Ma
- first_name: T.
full_name: Drye, T.
last_name: Drye
- first_name: C.
full_name: Nucklos, C.
last_name: Nucklos
- first_name: S.
full_name: Lindsey, S.
last_name: Lindsey
- first_name: D.
full_name: Rhodes, D.
last_name: Rhodes
- first_name: Q.
full_name: Zhang, Q.
last_name: Zhang
- first_name: Kimberly A
full_name: Modic, Kimberly A
id: 13C26AC0-EB69-11E9-87C6-5F3BE6697425
last_name: Modic
orcid: 0000-0001-9760-3147
- first_name: S.
full_name: Cawthorne, S.
last_name: Cawthorne
- first_name: F.
full_name: Drymiotis, F.
last_name: Drymiotis
citation:
ama: Capps J, Ma B, Drye T, et al. The effect of Ag concentration on the structural,
electrical and thermal transport behavior of Pb:Te:Ag:Se mixtures and improvement
of thermoelectric performance via Cu doping. Journal of Alloys and Compounds.
2011;509(5):1544-1549. doi:10.1016/j.jallcom.2010.10.187
apa: Capps, J., Ma, B., Drye, T., Nucklos, C., Lindsey, S., Rhodes, D., … Drymiotis,
F. (2011). The effect of Ag concentration on the structural, electrical and thermal
transport behavior of Pb:Te:Ag:Se mixtures and improvement of thermoelectric performance
via Cu doping. Journal of Alloys and Compounds. Elsevier. https://doi.org/10.1016/j.jallcom.2010.10.187
chicago: Capps, J., B. Ma, T. Drye, C. Nucklos, S. Lindsey, D. Rhodes, Q. Zhang,
Kimberly A Modic, S. Cawthorne, and F. Drymiotis. “The Effect of Ag Concentration
on the Structural, Electrical and Thermal Transport Behavior of Pb:Te:Ag:Se Mixtures
and Improvement of Thermoelectric Performance via Cu Doping.” Journal of Alloys
and Compounds. Elsevier, 2011. https://doi.org/10.1016/j.jallcom.2010.10.187.
ieee: J. Capps et al., “The effect of Ag concentration on the structural,
electrical and thermal transport behavior of Pb:Te:Ag:Se mixtures and improvement
of thermoelectric performance via Cu doping,” Journal of Alloys and Compounds,
vol. 509, no. 5. Elsevier, pp. 1544–1549, 2011.
ista: Capps J, Ma B, Drye T, Nucklos C, Lindsey S, Rhodes D, Zhang Q, Modic KA,
Cawthorne S, Drymiotis F. 2011. The effect of Ag concentration on the structural,
electrical and thermal transport behavior of Pb:Te:Ag:Se mixtures and improvement
of thermoelectric performance via Cu doping. Journal of Alloys and Compounds.
509(5), 1544–1549.
mla: Capps, J., et al. “The Effect of Ag Concentration on the Structural, Electrical
and Thermal Transport Behavior of Pb:Te:Ag:Se Mixtures and Improvement of Thermoelectric
Performance via Cu Doping.” Journal of Alloys and Compounds, vol. 509,
no. 5, Elsevier, 2011, pp. 1544–49, doi:10.1016/j.jallcom.2010.10.187.
short: J. Capps, B. Ma, T. Drye, C. Nucklos, S. Lindsey, D. Rhodes, Q. Zhang, K.A.
Modic, S. Cawthorne, F. Drymiotis, Journal of Alloys and Compounds 509 (2011)
1544–1549.
date_created: 2019-11-19T13:45:37Z
date_published: 2011-02-03T00:00:00Z
date_updated: 2021-01-12T08:11:44Z
day: '03'
doi: 10.1016/j.jallcom.2010.10.187
extern: '1'
intvolume: ' 509'
issue: '5'
language:
- iso: eng
month: '02'
oa_version: None
page: 1544-1549
publication: Journal of Alloys and Compounds
publication_identifier:
issn:
- 0925-8388
publication_status: published
publisher: Elsevier
quality_controlled: '1'
status: public
title: The effect of Ag concentration on the structural, electrical and thermal transport
behavior of Pb:Te:Ag:Se mixtures and improvement of thermoelectric performance via
Cu doping
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 509
year: '2011'
...
---
_id: '7313'
abstract:
- lang: eng
text: 'Li-ion batteries have transformed portable electronics and will play a key
role in the electrification of transport. However, the highest energy storage
possible for Li-ion batteries is insufficient for the long-term needs of society,
for example, extended-range electric vehicles. To go beyond the horizon of Li-ion
batteries is a formidable challenge; there are few options. Here we consider two:
Li–air (O2) and Li–S. The energy that can be stored in Li–air (based on aqueous
or non-aqueous electrolytes) and Li–S cells is compared with Li-ion; the operation
of the cells is discussed, as are the significant hurdles that will have to be
overcome if such batteries are to succeed. Fundamental scientific advances in
understanding the reactions occurring in the cells as well as new materials are
key to overcoming these obstacles. The potential benefits of Li–air and Li–S justify
the continued research effort that will be needed.'
article_processing_charge: No
article_type: original
author:
- first_name: Peter G.
full_name: Bruce, Peter G.
last_name: Bruce
- first_name: Stefan Alexander
full_name: Freunberger, Stefan Alexander
id: A8CA28E6-CE23-11E9-AD2D-EC27E6697425
last_name: Freunberger
orcid: 0000-0003-2902-5319
- first_name: Laurence J.
full_name: Hardwick, Laurence J.
last_name: Hardwick
- first_name: Jean-Marie
full_name: Tarascon, Jean-Marie
last_name: Tarascon
citation:
ama: Bruce PG, Freunberger SA, Hardwick LJ, Tarascon J-M. Li–O2 and Li–S batteries
with high energy storage. Nature Materials. 2011;11(1):19-29. doi:10.1038/nmat3191
apa: Bruce, P. G., Freunberger, S. A., Hardwick, L. J., & Tarascon, J.-M. (2011).
Li–O2 and Li–S batteries with high energy storage. Nature Materials. Springer
Nature. https://doi.org/10.1038/nmat3191
chicago: Bruce, Peter G., Stefan Alexander Freunberger, Laurence J. Hardwick, and
Jean-Marie Tarascon. “Li–O2 and Li–S Batteries with High Energy Storage.” Nature
Materials. Springer Nature, 2011. https://doi.org/10.1038/nmat3191.
ieee: P. G. Bruce, S. A. Freunberger, L. J. Hardwick, and J.-M. Tarascon, “Li–O2
and Li–S batteries with high energy storage,” Nature Materials, vol. 11,
no. 1. Springer Nature, pp. 19–29, 2011.
ista: Bruce PG, Freunberger SA, Hardwick LJ, Tarascon J-M. 2011. Li–O2 and Li–S
batteries with high energy storage. Nature Materials. 11(1), 19–29.
mla: Bruce, Peter G., et al. “Li–O2 and Li–S Batteries with High Energy Storage.”
Nature Materials, vol. 11, no. 1, Springer Nature, 2011, pp. 19–29, doi:10.1038/nmat3191.
short: P.G. Bruce, S.A. Freunberger, L.J. Hardwick, J.-M. Tarascon, Nature Materials
11 (2011) 19–29.
date_created: 2020-01-15T12:20:01Z
date_published: 2011-12-15T00:00:00Z
date_updated: 2021-01-12T08:12:59Z
day: '15'
doi: 10.1038/nmat3191
extern: '1'
intvolume: ' 11'
issue: '1'
language:
- iso: eng
month: '12'
oa_version: None
page: 19-29
publication: Nature Materials
publication_identifier:
issn:
- 1476-1122
- 1476-4660
publication_status: published
publisher: Springer Nature
quality_controlled: '1'
related_material:
link:
- relation: erratum
url: https://doi.org/10.1038/nmat3237
status: public
title: Li–O2 and Li–S batteries with high energy storage
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 11
year: '2011'
...