[{"publist_id":"4472","author":[{"last_name":"Nevo","full_name":"Nevo, Eran","first_name":"Eran"},{"last_name":"Wagner","full_name":"Uli Wagner","orcid":"0000-0002-1494-0568","first_name":"Uli","id":"36690CA2-F248-11E8-B48F-1D18A9856A87"}],"title":"On the embeddability of skeleta of spheres","citation":{"ista":"Nevo E, Wagner U. 2010. On the embeddability of skeleta of spheres. Israel Journal of Mathematics. 174(1), 381–402.","chicago":"Nevo, Eran, and Uli Wagner. “On the Embeddability of Skeleta of Spheres.” Israel Journal of Mathematics. Springer, 2010. https://doi.org/10.1007/s11856-009-0119-5.","apa":"Nevo, E., & Wagner, U. (2010). On the embeddability of skeleta of spheres. Israel Journal of Mathematics. Springer. https://doi.org/10.1007/s11856-009-0119-5","ama":"Nevo E, Wagner U. On the embeddability of skeleta of spheres. Israel Journal of Mathematics. 2010;174(1):381-402. doi:10.1007/s11856-009-0119-5","short":"E. Nevo, U. Wagner, Israel Journal of Mathematics 174 (2010) 381–402.","ieee":"E. Nevo and U. Wagner, “On the embeddability of skeleta of spheres,” Israel Journal of Mathematics, vol. 174, no. 1. Springer, pp. 381–402, 2010.","mla":"Nevo, Eran, and Uli Wagner. “On the Embeddability of Skeleta of Spheres.” Israel Journal of Mathematics, vol. 174, no. 1, Springer, 2010, pp. 381–402, doi:10.1007/s11856-009-0119-5."},"date_updated":"2021-01-12T06:57:28Z","extern":1,"type":"journal_article","status":"public","_id":"2435","page":"381 - 402","date_created":"2018-12-11T11:57:38Z","volume":174,"issue":"1","date_published":"2010-11-01T00:00:00Z","doi":"10.1007/s11856-009-0119-5","year":"2010","publication_status":"published","publication":"Israel Journal of Mathematics","day":"01","publisher":"Springer","quality_controlled":0,"intvolume":" 174","month":"11","abstract":[{"text":"We consider a generalization of the van Kampen-Flores Theorem and relate it to the long-standing g-conjecture for simplicial spheres.\n","lang":"eng"}]},{"title":"Nitrate Contra Auxin: Nutrient Sensing by roots","publist_id":"4461","author":[{"first_name":"Tom","full_name":"Beeckman, Tom","last_name":"Beeckman"},{"first_name":"Jirí","id":"4159519E-F248-11E8-B48F-1D18A9856A87","orcid":"0000-0002-8302-7596","full_name":"Friml, Jirí","last_name":"Friml"}],"external_id":{"pmid":[" 20627068"]},"user_id":"3E5EF7F0-F248-11E8-B48F-1D18A9856A87","citation":{"mla":"Beeckman, Tom, and Jiří Friml. “Nitrate Contra Auxin: Nutrient Sensing by Roots.” Developmental Cell, vol. 18, no. 6, Cell Press, 2010, pp. 877–78, doi:10.1016/j.devcel.2010.05.020.","apa":"Beeckman, T., & Friml, J. (2010). Nitrate Contra Auxin: Nutrient Sensing by roots. Developmental Cell. Cell Press. https://doi.org/10.1016/j.devcel.2010.05.020","ama":"Beeckman T, Friml J. Nitrate Contra Auxin: Nutrient Sensing by roots. Developmental Cell. 2010;18(6):877-878. doi:10.1016/j.devcel.2010.05.020","short":"T. Beeckman, J. Friml, Developmental Cell 18 (2010) 877–878.","ieee":"T. Beeckman and J. Friml, “Nitrate Contra Auxin: Nutrient Sensing by roots,” Developmental Cell, vol. 18, no. 6. Cell Press, pp. 877–878, 2010.","chicago":"Beeckman, Tom, and Jiří Friml. “Nitrate Contra Auxin: Nutrient Sensing by Roots.” Developmental Cell. Cell Press, 2010. https://doi.org/10.1016/j.devcel.2010.05.020.","ista":"Beeckman T, Friml J. 2010. Nitrate Contra Auxin: Nutrient Sensing by roots. Developmental Cell. 18(6), 877–878."},"quality_controlled":"1","publisher":"Cell Press","oa":1,"date_published":"2010-06-15T00:00:00Z","doi":"10.1016/j.devcel.2010.05.020","date_created":"2018-12-11T11:57:41Z","page":"877 - 878","day":"15","publication":"Developmental Cell","year":"2010","status":"public","type":"journal_article","_id":"2442","extern":"1","date_updated":"2021-01-12T06:57:31Z","month":"06","intvolume":" 18","main_file_link":[{"url":"https://www.ncbi.nlm.nih.gov/pubmed/20627068","open_access":"1"}],"pmid":1,"oa_version":"Published Version","abstract":[{"lang":"eng","text":"In a new study published in this issue of Developmental Cell, Krouk et al. reveal a surprising mechanism by which plant root systems adapt their architecture for soil exploitation. The dual transporter NRT1.1 uses both nitrate and the plant hormone auxin as substrates, enabling soil nitrate availability to regulate auxin-driven lateral root development."}],"volume":18,"issue":"6","language":[{"iso":"eng"}],"publication_status":"published"},{"status":"public","type":"journal_article","_id":"2503","title":"Disruption of LGI1-linked synaptic complex causes abnormal synaptic transmission and epilepsy","publist_id":"4398","author":[{"last_name":"Fukata","full_name":"Fukata, Yuko","first_name":"Yuko"},{"first_name":"Kathryn","full_name":"Lovero, Kathryn L","last_name":"Lovero"},{"first_name":"Tsuyoshi","last_name":"Iwanaga","full_name":"Iwanaga, Tsuyoshi"},{"full_name":"Watanabe, Atsushi","last_name":"Watanabe","first_name":"Atsushi"},{"full_name":"Yokoi, Norihiko","last_name":"Yokoi","first_name":"Norihiko"},{"last_name":"Tabuchi","full_name":"Tabuchi, Katsuhiko","first_name":"Katsuhiko"},{"first_name":"Ryuichi","id":"499F3ABC-F248-11E8-B48F-1D18A9856A87","last_name":"Shigemoto","orcid":"0000-0001-8761-9444","full_name":"Ryuichi Shigemoto"},{"first_name":"Roger","full_name":"Nicoll, Roger A","last_name":"Nicoll"},{"full_name":"Fukata, Masaki","last_name":"Fukata","first_name":"Masaki"}],"extern":1,"citation":{"mla":"Fukata, Yuko, et al. “Disruption of LGI1-Linked Synaptic Complex Causes Abnormal Synaptic Transmission and Epilepsy.” PNAS, vol. 107, no. 8, National Academy of Sciences, 2010, pp. 3799–804, doi:10.1073/pnas.0914537107.","ama":"Fukata Y, Lovero K, Iwanaga T, et al. Disruption of LGI1-linked synaptic complex causes abnormal synaptic transmission and epilepsy. PNAS. 2010;107(8):3799-3804. doi:10.1073/pnas.0914537107","apa":"Fukata, Y., Lovero, K., Iwanaga, T., Watanabe, A., Yokoi, N., Tabuchi, K., … Fukata, M. (2010). Disruption of LGI1-linked synaptic complex causes abnormal synaptic transmission and epilepsy. PNAS. National Academy of Sciences. https://doi.org/10.1073/pnas.0914537107","ieee":"Y. Fukata et al., “Disruption of LGI1-linked synaptic complex causes abnormal synaptic transmission and epilepsy,” PNAS, vol. 107, no. 8. National Academy of Sciences, pp. 3799–3804, 2010.","short":"Y. Fukata, K. Lovero, T. Iwanaga, A. Watanabe, N. Yokoi, K. Tabuchi, R. Shigemoto, R. Nicoll, M. Fukata, PNAS 107 (2010) 3799–3804.","chicago":"Fukata, Yuko, Kathryn Lovero, Tsuyoshi Iwanaga, Atsushi Watanabe, Norihiko Yokoi, Katsuhiko Tabuchi, Ryuichi Shigemoto, Roger Nicoll, and Masaki Fukata. “Disruption of LGI1-Linked Synaptic Complex Causes Abnormal Synaptic Transmission and Epilepsy.” PNAS. National Academy of Sciences, 2010. https://doi.org/10.1073/pnas.0914537107.","ista":"Fukata Y, Lovero K, Iwanaga T, Watanabe A, Yokoi N, Tabuchi K, Shigemoto R, Nicoll R, Fukata M. 2010. Disruption of LGI1-linked synaptic complex causes abnormal synaptic transmission and epilepsy. PNAS. 107(8), 3799–3804."},"date_updated":"2021-01-12T06:57:53Z","month":"02","intvolume":" 107","quality_controlled":0,"publisher":"National Academy of Sciences","abstract":[{"text":"Epilepsy is a devastating and poorly understood disease. Mutations in a secreted neuronal protein, leucine-rich glioma inactivated 1 (LGI1), were reported in patients with an inherited form of human epilepsy, autosomal dominant partial epilepsy with auditory features (ADPEAF). Here, we report an essential role of LGI1 as an antiepileptogenic ligand. We find that loss of LGI1 in mice (LGI1-/-) causes lethal epilepsy, which is specifically rescued by the neuronal expression of LGI1 transgene, but not LGI3. Moreover, heterozygous mice for the LGI1 mutation (LGI1+/-) show lowered seizure thresholds. Extracellularly secreted LGI1 links two epilepsy-related receptors, ADAM22 and ADAM23, in the brain and organizes a transsynaptic protein complex that includes presynaptic potassium channels and postsynaptic AMPA receptor scaffolds. A lack of LGI1 disrupts this synaptic protein connection and selectively reduces AMPA receptor-mediated synaptic transmission in the hippocampus. Thus, LGI1 may serve as a major determinant of brain excitation, and the LGI1 gene-targeted mouse provides a good model for human epilepsy.","lang":"eng"}],"volume":107,"issue":"8","date_published":"2010-02-23T00:00:00Z","doi":"10.1073/pnas.0914537107","date_created":"2018-12-11T11:58:03Z","page":"3799 - 3804","day":"23","publication":"PNAS","publication_status":"published","year":"2010"},{"_id":"2508","status":"public","type":"journal_article","extern":1,"date_updated":"2021-01-12T06:57:54Z","citation":{"chicago":"Atherton, Jeremy, Katsunori Kitano, Jérôme Baufreton, Kai Fan, David Wokosin, Tatiana Tkatch, Ryuichi Shigemoto, James Surmeier, and Mark Bevan. “Selective Participation of Somatodendritic HCN Channels in Inhibitory but Not Excitatory Synaptic Integration in Neurons of the Subthalamic Nucleus.” Journal of Neuroscience. Society for Neuroscience, 2010. https://doi.org/10.1523/JNEUROSCI.3898-10.2010.","ista":"Atherton J, Kitano K, Baufreton J, Fan K, Wokosin D, Tkatch T, Shigemoto R, Surmeier J, Bevan M. 2010. Selective participation of somatodendritic HCN channels in inhibitory but not excitatory synaptic integration in neurons of the subthalamic nucleus. Journal of Neuroscience. 30(47), 16025–16040.","mla":"Atherton, Jeremy, et al. “Selective Participation of Somatodendritic HCN Channels in Inhibitory but Not Excitatory Synaptic Integration in Neurons of the Subthalamic Nucleus.” Journal of Neuroscience, vol. 30, no. 47, Society for Neuroscience, 2010, pp. 16025–40, doi:10.1523/JNEUROSCI.3898-10.2010.","short":"J. Atherton, K. Kitano, J. Baufreton, K. Fan, D. Wokosin, T. Tkatch, R. Shigemoto, J. Surmeier, M. Bevan, Journal of Neuroscience 30 (2010) 16025–16040.","ieee":"J. Atherton et al., “Selective participation of somatodendritic HCN channels in inhibitory but not excitatory synaptic integration in neurons of the subthalamic nucleus,” Journal of Neuroscience, vol. 30, no. 47. Society for Neuroscience, pp. 16025–16040, 2010.","ama":"Atherton J, Kitano K, Baufreton J, et al. Selective participation of somatodendritic HCN channels in inhibitory but not excitatory synaptic integration in neurons of the subthalamic nucleus. Journal of Neuroscience. 2010;30(47):16025-16040. doi:10.1523/JNEUROSCI.3898-10.2010","apa":"Atherton, J., Kitano, K., Baufreton, J., Fan, K., Wokosin, D., Tkatch, T., … Bevan, M. (2010). Selective participation of somatodendritic HCN channels in inhibitory but not excitatory synaptic integration in neurons of the subthalamic nucleus. Journal of Neuroscience. Society for Neuroscience. https://doi.org/10.1523/JNEUROSCI.3898-10.2010"},"title":"Selective participation of somatodendritic HCN channels in inhibitory but not excitatory synaptic integration in neurons of the subthalamic nucleus","author":[{"first_name":"Jeremy","full_name":"Atherton, Jeremy F","last_name":"Atherton"},{"first_name":"Katsunori","full_name":"Kitano, Katsunori","last_name":"Kitano"},{"last_name":"Baufreton","full_name":"Baufreton, Jérôme","first_name":"Jérôme"},{"full_name":"Fan, Kai","last_name":"Fan","first_name":"Kai"},{"full_name":"Wokosin, David L","last_name":"Wokosin","first_name":"David"},{"last_name":"Tkatch","full_name":"Tkatch, Tatiana","first_name":"Tatiana"},{"orcid":"0000-0001-8761-9444","full_name":"Ryuichi Shigemoto","last_name":"Shigemoto","id":"499F3ABC-F248-11E8-B48F-1D18A9856A87","first_name":"Ryuichi"},{"last_name":"Surmeier","full_name":"Surmeier, James D","first_name":"James"},{"first_name":"Mark","last_name":"Bevan","full_name":"Bevan, Mark D"}],"publist_id":"4393","abstract":[{"text":"The activity patterns of subthalamic nucleus (STN) neurons are intimately linked to motor function and dysfunction and arise through the complex interaction of intrinsic properties and inhibitory and excitatory synaptic inputs. In many neurons, hyperpolarization-activated cyclic nucleotide-gated (HCN) channels play key roles in intrinsic excitability and synaptic integration both under normal conditions and in disease states. However, in STN neurons, which strongly express HCN channels, their roles remain relatively obscure. To address this deficit, complementary molecular and cellular electrophysiological, imaging, and computational approaches were applied to the rat STN. Molecular profiling demonstrated that individual STN neurons express mRNA encoding several HCN subunits, with HCN2 and 3 being the most abundant. Light and electron microscopic analysis showed that HCN2 subunits are strongly expressed and distributed throughout the somatodendritic plasma membrane. Voltage-, current-, and dynamic-clamp analysis, two-photon Ca 2+ imaging, and computational modeling revealed that HCN channels are activated by GABA A receptor-mediated inputs and thus limit synaptic hyperpolarization and deinactivation of low-voltage-activated Ca 2+ channels. Although HCN channels also limited the temporal summation of EPSPs, generated through two-photon uncaging of glutamate, this action was largely shunted by GABAergic inhibition that was necessary for HCN channel activation. Together the data demonstrate that HCN channels in STN neurons selectively counteract GABA A receptor-mediated inhibition arising from the globus pallidus and thus promote single-spike activity rather than rebound burst firing. ","lang":"eng"}],"month":"11","intvolume":" 30","publisher":"Society for Neuroscience","quality_controlled":0,"day":"24","publication":"Journal of Neuroscience","publication_status":"published","year":"2010","doi":"10.1523/JNEUROSCI.3898-10.2010","issue":"47","volume":30,"date_published":"2010-11-24T00:00:00Z","date_created":"2018-12-11T11:58:05Z","page":"16025 - 16040"},{"month":"11","intvolume":" 32","publisher":"Wiley-Blackwell","quality_controlled":0,"abstract":[{"lang":"eng","text":"Hippocampal CA1 pyramidal cells, which receive γ-aminobutyric acid (GABA)ergic input from at least 18 types of presynaptic neuron, express 14 subunits of the pentameric GABAA receptor. The relative contribution of any subunit to synaptic and extrasynaptic receptors influences the dynamics of GABA and drug actions. Synaptic receptors mediate phasic GABA-evoked conductance and extrasynaptic receptors contribute to a tonic conductance. We used freeze-fracture replica-immunogold labelling, a sensitive quantitative immunocytochemical method, to detect synaptic and extrasynaptic pools of the alpha1, alpha2 and beta3 subunits. Antibodies to the cytoplasmic loop of the subunits showed immunogold particles concentrated on distinct clusters of intramembrane particles (IMPs) on the cytoplasmic face of the plasma membrane on the somata, dendrites and axon initial segments, with an abrupt decrease in labelling at the edge of the IMP cluster. Neuroligin-2, a GABAergic synapse-specific adhesion molecule, co-labels all beta3 subunit-rich IMP clusters, therefore we considered them synapses. Double-labelling for two subunits showed that virtually all somatic synapses contain the alpha1, alpha2 and beta3 subunits. The extrasynaptic plasma membrane of the somata, dendrites and dendritic spines showed low-density immunolabelling. Synaptic labelling densities on somata for the alpha1, alpha2 and beta3 subunits were 78-132, 94 and 79 times higher than on the extrasynaptic membranes, respectively. As GABAergic synapses occupy 0.72% of the soma surface, the fraction of synaptic labelling was 33-48 (alpha1), 40 (alpha2) and 36 (beta3)% of the total somatic surface immunolabelling. Assuming similar antibody access to all receptors, about 60% of these subunits are in extrasynaptic receptors."}],"date_published":"2010-11-14T00:00:00Z","doi":"10.1111/j.1460-9568.2010.07473.x","issue":"11","volume":32,"date_created":"2018-12-11T11:58:05Z","page":"1868 - 1888","day":"14","publication":"European Journal of Neuroscience","year":"2010","publication_status":"published","status":"public","type":"journal_article","_id":"2509","title":"Quantitative localisation of synaptic and extrasynaptic GABAA receptor subunits on hippocampal pyramidal cells by freeze-fracture replica immunolabelling","publist_id":"4392","author":[{"last_name":"Kasugai","full_name":"Kasugai, Yu","first_name":"Yu"},{"first_name":"Jerome","full_name":"Swinny, Jerome D","last_name":"Swinny"},{"first_name":"John","last_name":"Roberts","full_name":"Roberts, John D"},{"last_name":"Dalezios","full_name":"Dalezios, Yannis","first_name":"Yannis"},{"last_name":"Fukazawa","full_name":"Fukazawa, Yugo","first_name":"Yugo"},{"first_name":"Werner","last_name":"Sieghart","full_name":"Sieghart, Werner C"},{"id":"499F3ABC-F248-11E8-B48F-1D18A9856A87","first_name":"Ryuichi","last_name":"Shigemoto","orcid":"0000-0001-8761-9444","full_name":"Ryuichi Shigemoto"},{"first_name":"Péter","last_name":"Somogyi","full_name":"Somogyi, Péter"}],"extern":1,"date_updated":"2021-01-12T06:57:55Z","citation":{"mla":"Kasugai, Yu, et al. “Quantitative Localisation of Synaptic and Extrasynaptic GABAA Receptor Subunits on Hippocampal Pyramidal Cells by Freeze-Fracture Replica Immunolabelling.” European Journal of Neuroscience, vol. 32, no. 11, Wiley-Blackwell, 2010, pp. 1868–88, doi:10.1111/j.1460-9568.2010.07473.x.","ieee":"Y. Kasugai et al., “Quantitative localisation of synaptic and extrasynaptic GABAA receptor subunits on hippocampal pyramidal cells by freeze-fracture replica immunolabelling,” European Journal of Neuroscience, vol. 32, no. 11. Wiley-Blackwell, pp. 1868–1888, 2010.","short":"Y. Kasugai, J. Swinny, J. Roberts, Y. Dalezios, Y. Fukazawa, W. Sieghart, R. Shigemoto, P. Somogyi, European Journal of Neuroscience 32 (2010) 1868–1888.","apa":"Kasugai, Y., Swinny, J., Roberts, J., Dalezios, Y., Fukazawa, Y., Sieghart, W., … Somogyi, P. (2010). Quantitative localisation of synaptic and extrasynaptic GABAA receptor subunits on hippocampal pyramidal cells by freeze-fracture replica immunolabelling. European Journal of Neuroscience. Wiley-Blackwell. https://doi.org/10.1111/j.1460-9568.2010.07473.x","ama":"Kasugai Y, Swinny J, Roberts J, et al. Quantitative localisation of synaptic and extrasynaptic GABAA receptor subunits on hippocampal pyramidal cells by freeze-fracture replica immunolabelling. European Journal of Neuroscience. 2010;32(11):1868-1888. doi:10.1111/j.1460-9568.2010.07473.x","chicago":"Kasugai, Yu, Jerome Swinny, John Roberts, Yannis Dalezios, Yugo Fukazawa, Werner Sieghart, Ryuichi Shigemoto, and Péter Somogyi. “Quantitative Localisation of Synaptic and Extrasynaptic GABAA Receptor Subunits on Hippocampal Pyramidal Cells by Freeze-Fracture Replica Immunolabelling.” European Journal of Neuroscience. Wiley-Blackwell, 2010. https://doi.org/10.1111/j.1460-9568.2010.07473.x.","ista":"Kasugai Y, Swinny J, Roberts J, Dalezios Y, Fukazawa Y, Sieghart W, Shigemoto R, Somogyi P. 2010. Quantitative localisation of synaptic and extrasynaptic GABAA receptor subunits on hippocampal pyramidal cells by freeze-fracture replica immunolabelling. European Journal of Neuroscience. 32(11), 1868–1888."}},{"_id":"2510","status":"public","type":"journal_article","extern":1,"citation":{"chicago":"Dong, Yu, Yugo Fukazawa, Wen Wang, Naomi Kamasawa, and Ryuichi Shigemoto. “Differential Postsynaptic Compartments in the Laterocapsular Division of the Central Nucleus of Amygdala for Afferents from the Parabrachial Nucleus and the Basolateral Nucleus in the Rat.” Journal of Comparative Neurology. Wiley-Blackwell, 2010. https://doi.org/10.1002/cne.22487.","ista":"Dong Y, Fukazawa Y, Wang W, Kamasawa N, Shigemoto R. 2010. Differential postsynaptic compartments in the laterocapsular division of the central nucleus of amygdala for afferents from the parabrachial nucleus and the basolateral nucleus in the rat. Journal of Comparative Neurology. 518(23), 4771–4791.","mla":"Dong, Yu, et al. “Differential Postsynaptic Compartments in the Laterocapsular Division of the Central Nucleus of Amygdala for Afferents from the Parabrachial Nucleus and the Basolateral Nucleus in the Rat.” Journal of Comparative Neurology, vol. 518, no. 23, Wiley-Blackwell, 2010, pp. 4771–91, doi:10.1002/cne.22487.","apa":"Dong, Y., Fukazawa, Y., Wang, W., Kamasawa, N., & Shigemoto, R. (2010). Differential postsynaptic compartments in the laterocapsular division of the central nucleus of amygdala for afferents from the parabrachial nucleus and the basolateral nucleus in the rat. Journal of Comparative Neurology. Wiley-Blackwell. https://doi.org/10.1002/cne.22487","ama":"Dong Y, Fukazawa Y, Wang W, Kamasawa N, Shigemoto R. Differential postsynaptic compartments in the laterocapsular division of the central nucleus of amygdala for afferents from the parabrachial nucleus and the basolateral nucleus in the rat. Journal of Comparative Neurology. 2010;518(23):4771-4791. doi:10.1002/cne.22487","short":"Y. Dong, Y. Fukazawa, W. Wang, N. Kamasawa, R. Shigemoto, Journal of Comparative Neurology 518 (2010) 4771–4791.","ieee":"Y. Dong, Y. Fukazawa, W. Wang, N. Kamasawa, and R. Shigemoto, “Differential postsynaptic compartments in the laterocapsular division of the central nucleus of amygdala for afferents from the parabrachial nucleus and the basolateral nucleus in the rat,” Journal of Comparative Neurology, vol. 518, no. 23. Wiley-Blackwell, pp. 4771–4791, 2010."},"date_updated":"2021-01-12T06:57:55Z","title":"Differential postsynaptic compartments in the laterocapsular division of the central nucleus of amygdala for afferents from the parabrachial nucleus and the basolateral nucleus in the rat","author":[{"first_name":"Yu","full_name":"Dong, Yu-Lin","last_name":"Dong"},{"first_name":"Yugo","full_name":"Fukazawa, Yugo","last_name":"Fukazawa"},{"first_name":"Wen","full_name":"Wang, Wen","last_name":"Wang"},{"full_name":"Kamasawa, Naomi","last_name":"Kamasawa","first_name":"Naomi"},{"last_name":"Shigemoto","full_name":"Ryuichi Shigemoto","orcid":"0000-0001-8761-9444","id":"499F3ABC-F248-11E8-B48F-1D18A9856A87","first_name":"Ryuichi"}],"publist_id":"4391","abstract":[{"lang":"eng","text":"Neurons in the laterocapsular division of the central nucleus of the amygdala (CeC), which is known as the "nociceptive amygdala," receive glutamatergic inputs from the parabrachial nucleus (PB) and the basolateral nucleus of amygdala (BLA), which convey nociceptive information from the dorsal horn of the spinal cord and polymodal information from the thalamus and cortex, respectively. Here, we examined the ultrastructural properties of PB- and BLA-CeC synapses identified with EGFP-expressing lentivirus in rats. In addition, the density of synaptic AMPA receptors (AMPARs) on CeC neurons was studied by using highly sensitive SDS-digested freeze-fracture replica labeling (SDS-FRL). Afferents from the PB made asymmetrical synapses mainly on dendritic shafts (88%), whereas those from the BLA were on dendritic spines (81%). PB-CeC synapses in dendritic shafts were significantly larger (median 0.072 μm 2) than BLA-CeC synapses in spines (median 0.058 μm 2; P = 0.02). The dendritic shafts that made synapses with PB fibers were also significantly larger than those that made synapses with BLA fibers, indicating that the PB fibers make synapses on more proximal parts of dendrites than the BLA fibers. SDS-FRL revealed that almost all excitatory postsynaptic sites have AMPARs in the CeC. The density of AMPAR-specific gold particles in individual synapses was significantly higher in spine synapses (median 510 particles/μm 2) than in shaft synapses (median 427 particles/μm 2; P = 0.01). These results suggest that distinct synaptic impacts from PB- and BLA-CeC pathways contribute to the integration of nociceptive and polymodal information in the CeC."}],"intvolume":" 518","month":"12","quality_controlled":0,"publisher":"Wiley-Blackwell","publication":"Journal of Comparative Neurology","day":"01","publication_status":"published","year":"2010","date_created":"2018-12-11T11:58:05Z","issue":"23","date_published":"2010-12-01T00:00:00Z","volume":518,"doi":"10.1002/cne.22487","page":"4771 - 4791"},{"_id":"2506","type":"journal_article","status":"public","citation":{"chicago":"Furuya, Sonoko, Kishio Furuya, Ryuichi Shigemoto, and Masahiro Sokabe. “Localization of NK1 Receptors and Roles of Substance-P in Subepithelial Fibroblasts of Rat Intestinal Villi.” Cell and Tissue Research. Springer, 2010. https://doi.org/10.1007/s00441-010-1056-7.","ista":"Furuya S, Furuya K, Shigemoto R, Sokabe M. 2010. Localization of NK1 receptors and roles of substance-P in subepithelial fibroblasts of rat intestinal villi. Cell and Tissue Research. 342(2), 243–259.","mla":"Furuya, Sonoko, et al. “Localization of NK1 Receptors and Roles of Substance-P in Subepithelial Fibroblasts of Rat Intestinal Villi.” Cell and Tissue Research, vol. 342, no. 2, Springer, 2010, pp. 243–59, doi:10.1007/s00441-010-1056-7.","apa":"Furuya, S., Furuya, K., Shigemoto, R., & Sokabe, M. (2010). Localization of NK1 receptors and roles of substance-P in subepithelial fibroblasts of rat intestinal villi. Cell and Tissue Research. Springer. https://doi.org/10.1007/s00441-010-1056-7","ama":"Furuya S, Furuya K, Shigemoto R, Sokabe M. Localization of NK1 receptors and roles of substance-P in subepithelial fibroblasts of rat intestinal villi. Cell and Tissue Research. 2010;342(2):243-259. doi:10.1007/s00441-010-1056-7","ieee":"S. Furuya, K. Furuya, R. Shigemoto, and M. Sokabe, “Localization of NK1 receptors and roles of substance-P in subepithelial fibroblasts of rat intestinal villi,” Cell and Tissue Research, vol. 342, no. 2. Springer, pp. 243–259, 2010.","short":"S. Furuya, K. Furuya, R. Shigemoto, M. Sokabe, Cell and Tissue Research 342 (2010) 243–259."},"date_updated":"2021-01-12T06:57:54Z","extern":1,"publist_id":"4395","author":[{"full_name":"Furuya, Sonoko","last_name":"Furuya","first_name":"Sonoko"},{"last_name":"Furuya","full_name":"Furuya, Kishio","first_name":"Kishio"},{"id":"499F3ABC-F248-11E8-B48F-1D18A9856A87","first_name":"Ryuichi","last_name":"Shigemoto","orcid":"0000-0001-8761-9444","full_name":"Ryuichi Shigemoto"},{"first_name":"Masahiro","full_name":"Sokabe, Masahiro","last_name":"Sokabe"}],"title":"Localization of NK1 receptors and roles of substance-P in subepithelial fibroblasts of rat intestinal villi","abstract":[{"text":"Subepithelial fibroblasts of the intestinal villi, which form a contractile cellular network beneath the epithelium, are in close contact with epithelial cells, nerve varicosities, capillaries, smooth muscles and immune cells, and secrete extracellular matrix molecules, growth factors and cytokines, etc. Cultured subepithelial fibroblasts of the rat duodenal villi display various receptors such as endothelins, ATP, substance-P and bradykinin, and release ATP in response to mechanical stimulation. In this study, the presence of functional NK1 receptors (NK1R) was pharmacologically confirmed in primary culture by Ca 2+ measurement, and the effects of substance-P were measured in an acute preparation of epithelium-free duodenal villi from 2- to 3-week-old rats using a two-photon laser microscope. Substance-P elicited an increase in the intracellular Ca 2+ concentration and contraction of the subepithelial fibroblasts in culture and the isolated villi. The localization of NK1R and substance-P in the villi was examined by light and electron microscopic immunohistochemistry. NK1R-like immunoreactivity was intensely localized on the plasma membrane of villous subepithelial fibroblasts in 10-day- to 4-week-old rats and mice and was decreased or absent in adulthood. The pericryptal fibroblasts of the small and large intestine were NK1R immuno-negative. These villous subepithelial fibroblasts form synapse-like structures with both substance-P-immunopositive and -immunonegative nerve varicosities. Here, we propose that the mutual interaction between villous subepithelial fibroblasts and afferent neurons via substance-P and ATP plays important roles in the maturation of the structure and function of the small intestine.","lang":"eng"}],"quality_controlled":0,"publisher":"Springer","intvolume":" 342","month":"11","year":"2010","publication_status":"published","publication":"Cell and Tissue Research","day":"01","page":"243 - 259","date_created":"2018-12-11T11:58:04Z","volume":342,"doi":"10.1007/s00441-010-1056-7","issue":"2","date_published":"2010-11-01T00:00:00Z"},{"publication_status":"published","year":"2010","day":"01","publication":"Journal of Comparative Neurology","page":"4362 - 4374","volume":518,"issue":"21","date_published":"2010-11-01T00:00:00Z","doi":"10.1002/cne.22461","date_created":"2018-12-11T11:58:04Z","abstract":[{"text":"T-type calcium channels play a pivotal role in regulating neural membrane excitability in the nervous system. However, the precise subcellular distributions of T-type channel subunits and their implication for membrane excitability are not well understood. Here we investigated the subcellular distribution of the α1G subunit of the calcium channel which is expressed highly in the mouse dorsal lateral geniculate nucleus (dLGN). Light microscopic analysis demonstrated that dLGN exhibits intense immunoperoxidase reactivity for the α1G subunit. Electron microscopic observation showed that the labeling was present in both the relay cells and interneurons and was found in the somatodendritic, but not axonal, domains of these cells. Most of the immunogold particles for the α1G subunit were either associated with the plasma membrane or the intracellular membranes. Reconstruction analysis of serial electron microscopic images revealed that the intensity of the intracellular labeling exhibited a gradient such that the labeling density was higher in the proximal dendrite and progressively decreased towards the distal dendrite. In contrast, the plasma membrane-associated particles were distributed with a uniform density over the somatodendritic surface of dLGN cells. The labeling density in the relay cell plasma membrane was about 3-fold higher than that of the interneurons. These results provide ultrastructural evidence for cell-type-specific expression levels and for uniform expression density of the α1G subunit over the plasma membrane of dLGN cells.","lang":"eng"}],"publisher":"Wiley-Blackwell","quality_controlled":0,"month":"11","intvolume":" 518","date_updated":"2021-01-12T06:57:54Z","citation":{"ista":"Parajuli L, Fukazawa Y, Watanabe M, Shigemoto R. 2010. Subcellular distribution of α1G subunit of T-type calcium channel in the mouse dorsal lateral geniculate nucleus. Journal of Comparative Neurology. 518(21), 4362–4374.","chicago":"Parajuli, Laxmi, Yugo Fukazawa, Masahiko Watanabe, and Ryuichi Shigemoto. “Subcellular Distribution of Α1G Subunit of T-Type Calcium Channel in the Mouse Dorsal Lateral Geniculate Nucleus.” Journal of Comparative Neurology. Wiley-Blackwell, 2010. https://doi.org/10.1002/cne.22461.","ieee":"L. Parajuli, Y. Fukazawa, M. Watanabe, and R. Shigemoto, “Subcellular distribution of α1G subunit of T-type calcium channel in the mouse dorsal lateral geniculate nucleus,” Journal of Comparative Neurology, vol. 518, no. 21. Wiley-Blackwell, pp. 4362–4374, 2010.","short":"L. Parajuli, Y. Fukazawa, M. Watanabe, R. Shigemoto, Journal of Comparative Neurology 518 (2010) 4362–4374.","ama":"Parajuli L, Fukazawa Y, Watanabe M, Shigemoto R. Subcellular distribution of α1G subunit of T-type calcium channel in the mouse dorsal lateral geniculate nucleus. Journal of Comparative Neurology. 2010;518(21):4362-4374. doi:10.1002/cne.22461","apa":"Parajuli, L., Fukazawa, Y., Watanabe, M., & Shigemoto, R. (2010). Subcellular distribution of α1G subunit of T-type calcium channel in the mouse dorsal lateral geniculate nucleus. Journal of Comparative Neurology. Wiley-Blackwell. https://doi.org/10.1002/cne.22461","mla":"Parajuli, Laxmi, et al. “Subcellular Distribution of Α1G Subunit of T-Type Calcium Channel in the Mouse Dorsal Lateral Geniculate Nucleus.” Journal of Comparative Neurology, vol. 518, no. 21, Wiley-Blackwell, 2010, pp. 4362–74, doi:10.1002/cne.22461."},"extern":1,"author":[{"first_name":"Laxmi","last_name":"Parajuli","full_name":"Parajuli, Laxmi K"},{"first_name":"Yugo","full_name":"Fukazawa, Yugo","last_name":"Fukazawa"},{"first_name":"Masahiko","last_name":"Watanabe","full_name":"Watanabe, Masahiko"},{"id":"499F3ABC-F248-11E8-B48F-1D18A9856A87","first_name":"Ryuichi","last_name":"Shigemoto","full_name":"Ryuichi Shigemoto","orcid":"0000-0001-8761-9444"}],"publist_id":"4394","title":"Subcellular distribution of α1G subunit of T-type calcium channel in the mouse dorsal lateral geniculate nucleus","_id":"2507","type":"journal_article","status":"public"},{"extern":1,"date_updated":"2021-01-12T06:57:53Z","citation":{"chicago":"Matsuda, Keiko, Eriko Miura, Taisuke Miyazaki, Wataru Kakegawa, Kyoichi Emi, Sakae Narumi, Yugo Fukazawa, et al. “Cbln1 Is a Ligand for an Orphan Glutamate Receptor Δ2, a Bidirectional Synapse Organizer.” Science. American Association for the Advancement of Science, 2010. https://doi.org/10.1126/science.1185152.","ista":"Matsuda K, Miura E, Miyazaki T, Kakegawa W, Emi K, Narumi S, Fukazawa Y, Ito Lshida A, Kondo T, Shigemoto R, Watanabe M, Yuzaki M. 2010. Cbln1 is a ligand for an orphan glutamate receptor δ2, a bidirectional synapse organizer. Science. 328(5976), 363–368.","mla":"Matsuda, Keiko, et al. “Cbln1 Is a Ligand for an Orphan Glutamate Receptor Δ2, a Bidirectional Synapse Organizer.” Science, vol. 328, no. 5976, American Association for the Advancement of Science, 2010, pp. 363–68, doi:10.1126/science.1185152.","short":"K. Matsuda, E. Miura, T. Miyazaki, W. Kakegawa, K. Emi, S. Narumi, Y. Fukazawa, A. Ito Lshida, T. Kondo, R. Shigemoto, M. Watanabe, M. Yuzaki, Science 328 (2010) 363–368.","ieee":"K. Matsuda et al., “Cbln1 is a ligand for an orphan glutamate receptor δ2, a bidirectional synapse organizer,” Science, vol. 328, no. 5976. American Association for the Advancement of Science, pp. 363–368, 2010.","apa":"Matsuda, K., Miura, E., Miyazaki, T., Kakegawa, W., Emi, K., Narumi, S., … Yuzaki, M. (2010). Cbln1 is a ligand for an orphan glutamate receptor δ2, a bidirectional synapse organizer. Science. American Association for the Advancement of Science. https://doi.org/10.1126/science.1185152","ama":"Matsuda K, Miura E, Miyazaki T, et al. Cbln1 is a ligand for an orphan glutamate receptor δ2, a bidirectional synapse organizer. Science. 2010;328(5976):363-368. doi:10.1126/science.1185152"},"title":"Cbln1 is a ligand for an orphan glutamate receptor δ2, a bidirectional synapse organizer","author":[{"last_name":"Matsuda","full_name":"Matsuda, Keiko","first_name":"Keiko"},{"full_name":"Miura, Eriko","last_name":"Miura","first_name":"Eriko"},{"last_name":"Miyazaki","full_name":"Miyazaki, Taisuke","first_name":"Taisuke"},{"full_name":"Kakegawa, Wataru","last_name":"Kakegawa","first_name":"Wataru"},{"full_name":"Emi, Kyoichi","last_name":"Emi","first_name":"Kyoichi"},{"full_name":"Narumi, Sakae","last_name":"Narumi","first_name":"Sakae"},{"first_name":"Yugo","full_name":"Fukazawa, Yugo","last_name":"Fukazawa"},{"full_name":"Ito-lshida, Aya","last_name":"Ito Lshida","first_name":"Aya"},{"last_name":"Kondo","full_name":"Kondo, Tetsuro","first_name":"Tetsuro"},{"full_name":"Ryuichi Shigemoto","orcid":"0000-0001-8761-9444","last_name":"Shigemoto","first_name":"Ryuichi","id":"499F3ABC-F248-11E8-B48F-1D18A9856A87"},{"first_name":"Masahiko","last_name":"Watanabe","full_name":"Watanabe, Masahiko"},{"full_name":"Yuzaki, Michisuke","last_name":"Yuzaki","first_name":"Michisuke"}],"publist_id":"4396","_id":"2505","status":"public","type":"journal_article","publication":"Science","day":"16","year":"2010","publication_status":"published","date_created":"2018-12-11T11:58:04Z","doi":"10.1126/science.1185152","issue":"5976","volume":328,"date_published":"2010-04-16T00:00:00Z","page":"363 - 368","abstract":[{"text":"Cbln1, secreted from cerebellar granule cells, and the orphan glutamate receptor 52 (GluD2), expressed by Purkinje cells, are essential for synapse integrity between these neurons in adult mice. Nevertheless, no endogenous binding partners for these molecules have been identified. We found that Cblnl binds directly to the N-terminal domain of GluD2. GluD2 expression by postsynaptic cells, combined with exogenously applied Cbln1, was necessary and sufficient to induce new synapses in vitro and in the adult cerebellum in vivo. Further, beads coated with recombinant Cbln1 directly induced presynaptic differentiation and indirectly caused clustering of postsynaptic molecules via GluD2. These results indicate that the Cbln1-GluD2 complex is a unique synapse organizer that acts bidirectionally on both pre- and postsynaptic components.","lang":"eng"}],"intvolume":" 328","month":"04","publisher":"American Association for the Advancement of Science","quality_controlled":0},{"extern":1,"citation":{"ista":"Loukanov A, Kamasawa N, Danev R, Shigemoto R, Nagayama K. 2010. Immunolocalization of multiple membrane proteins on a carbon replica with STEM and EDX. Ultramicroscopy. 110(4), 366–374.","chicago":"Loukanov, Alexandre, Naomi Kamasawa, Radostin Danev, Ryuichi Shigemoto, and Kuniaki Nagayama. “Immunolocalization of Multiple Membrane Proteins on a Carbon Replica with STEM and EDX.” Ultramicroscopy. Elsevier, 2010. https://doi.org/10.1016/j.ultramic.2010.01.016.","short":"A. Loukanov, N. Kamasawa, R. Danev, R. Shigemoto, K. Nagayama, Ultramicroscopy 110 (2010) 366–374.","ieee":"A. Loukanov, N. Kamasawa, R. Danev, R. Shigemoto, and K. Nagayama, “Immunolocalization of multiple membrane proteins on a carbon replica with STEM and EDX,” Ultramicroscopy, vol. 110, no. 4. Elsevier, pp. 366–374, 2010.","ama":"Loukanov A, Kamasawa N, Danev R, Shigemoto R, Nagayama K. Immunolocalization of multiple membrane proteins on a carbon replica with STEM and EDX. Ultramicroscopy. 2010;110(4):366-374. doi:10.1016/j.ultramic.2010.01.016","apa":"Loukanov, A., Kamasawa, N., Danev, R., Shigemoto, R., & Nagayama, K. (2010). Immunolocalization of multiple membrane proteins on a carbon replica with STEM and EDX. Ultramicroscopy. Elsevier. https://doi.org/10.1016/j.ultramic.2010.01.016","mla":"Loukanov, Alexandre, et al. “Immunolocalization of Multiple Membrane Proteins on a Carbon Replica with STEM and EDX.” Ultramicroscopy, vol. 110, no. 4, Elsevier, 2010, pp. 366–74, doi:10.1016/j.ultramic.2010.01.016."},"date_updated":"2021-01-12T06:57:53Z","title":"Immunolocalization of multiple membrane proteins on a carbon replica with STEM and EDX","author":[{"first_name":"Alexandre","full_name":"Loukanov, Alexandre R","last_name":"Loukanov"},{"first_name":"Naomi","full_name":"Kamasawa, Naomi","last_name":"Kamasawa"},{"last_name":"Danev","full_name":"Danev, Radostin S","first_name":"Radostin"},{"last_name":"Shigemoto","full_name":"Ryuichi Shigemoto","orcid":"0000-0001-8761-9444","first_name":"Ryuichi","id":"499F3ABC-F248-11E8-B48F-1D18A9856A87"},{"last_name":"Nagayama","full_name":"Nagayama, Kuniaki","first_name":"Kuniaki"}],"publist_id":"4397","_id":"2504","status":"public","type":"journal_article","publication":"Ultramicroscopy","day":"01","publication_status":"published","year":"2010","date_created":"2018-12-11T11:58:03Z","date_published":"2010-03-01T00:00:00Z","issue":"4","doi":"10.1016/j.ultramic.2010.01.016","volume":110,"page":"366 - 374","abstract":[{"lang":"eng","text":"We present a method for immunolabeling of multiple species of membrane proteins with high spatial resolution. It allows differentiation of equally sized very small markers with different chemical compositions, which leads to high labeling efficiency and reduces steric hindrance of closely spaced immunolabeled biomolecules. Markers such as CdSe/ZnS semiconductor quantum dots and colloidal gold particles are distinguished by differential contrast in high-angle annular detector dark-field STEM mode or by EDX microanalysis of their elemental contents. This method was tested by observation of labeled AMPA- and NMDA-type glutamate receptors on sodium-dodecyl-sulfate-digested replica prepared from rat hippocampus. To improve particle visibility and detectability, the replica films were made exclusively with carbon to avoid the high background of conventional platinum/carbon replica. Extension of the method is suggested by detection of 1.4 nm nanogold particles and its potential application in the biological imaging research."}],"intvolume":" 110","month":"03","publisher":"Elsevier","quality_controlled":0},{"abstract":[{"lang":"eng","text":"Consider a system of N bosons in three dimensions interacting via a repulsive short range pair potential N2V(N(xi-xj)), where x = (x1, ..., xN) denotes the positions of the particles. Let HN, denote the Hamiltonian of the system and let ψN,t be the solution to the Schrödinger equation. Suppose that the initial data ψN,0 satisfies the energy condition 〈 ψ N,0,Hk N ψN,0〉 ≤ CkNk for k =1, 2, ....We also assume that the k-particle density matrices of the initial state are asymptotically factorized as N →∞1. We prove that the k-particle density matrices of ψN,t are also asymptotically factorized and the one particle orbital wave function solves the Gross-Pitaevskii equation, a cubic nonlinear Schrödinger equation with the coupling constant given by the scattering length of the potential V. We also prove the same conclusion if the energy condition holds only for k=1 but the factorization of ψN,0 is assumed in a stronger sense."}],"quality_controlled":0,"publisher":"Princeton University Press","main_file_link":[{"url":"http://xxx.lanl.gov/abs/math-ph/0606017","open_access":"0"}],"month":"07","intvolume":" 172","publication_status":"published","year":"2010","day":"01","publication":"Annals of Mathematics","page":"291 - 370","doi":"10.4007/annals.2010.172.291","volume":172,"issue":"1","date_published":"2010-07-01T00:00:00Z","date_created":"2018-12-11T11:59:10Z","_id":"2704","type":"journal_article","status":"public","date_updated":"2021-01-12T06:59:10Z","citation":{"ista":"Erdös L, Schlein B, Yau H. 2010. Derivation of the Gross-Pitaevskii equation for the dynamics of Bose-Einstein condensate. Annals of Mathematics. 172(1), 291–370.","chicago":"Erdös, László, Benjamin Schlein, and Horng Yau. “Derivation of the Gross-Pitaevskii Equation for the Dynamics of Bose-Einstein Condensate.” Annals of Mathematics. Princeton University Press, 2010. https://doi.org/10.4007/annals.2010.172.291.","ama":"Erdös L, Schlein B, Yau H. Derivation of the Gross-Pitaevskii equation for the dynamics of Bose-Einstein condensate. Annals of Mathematics. 2010;172(1):291-370. doi:10.4007/annals.2010.172.291","apa":"Erdös, L., Schlein, B., & Yau, H. (2010). Derivation of the Gross-Pitaevskii equation for the dynamics of Bose-Einstein condensate. Annals of Mathematics. Princeton University Press. https://doi.org/10.4007/annals.2010.172.291","short":"L. Erdös, B. Schlein, H. Yau, Annals of Mathematics 172 (2010) 291–370.","ieee":"L. Erdös, B. Schlein, and H. Yau, “Derivation of the Gross-Pitaevskii equation for the dynamics of Bose-Einstein condensate,” Annals of Mathematics, vol. 172, no. 1. Princeton University Press, pp. 291–370, 2010.","mla":"Erdös, László, et al. “Derivation of the Gross-Pitaevskii Equation for the Dynamics of Bose-Einstein Condensate.” Annals of Mathematics, vol. 172, no. 1, Princeton University Press, 2010, pp. 291–370, doi:10.4007/annals.2010.172.291."},"extern":1,"publist_id":"4192","author":[{"last_name":"Erdös","full_name":"László Erdös","orcid":"0000-0001-5366-9603","first_name":"László","id":"4DBD5372-F248-11E8-B48F-1D18A9856A87"},{"first_name":"Benjamin","last_name":"Schlein","full_name":"Schlein, Benjamin"},{"full_name":"Yau, Horng-Tzer","last_name":"Yau","first_name":"Horng"}],"title":"Derivation of the Gross-Pitaevskii equation for the dynamics of Bose-Einstein condensate"},{"title":"Wegner estimate and level repulsion for Wigner random matrices","author":[{"last_name":"Erdös","orcid":"0000-0001-5366-9603","full_name":"László Erdös","id":"4DBD5372-F248-11E8-B48F-1D18A9856A87","first_name":"László"},{"first_name":"Benjamin","last_name":"Schlein","full_name":"Schlein, Benjamin"},{"last_name":"Yau","full_name":"Yau, Horng-Tzer","first_name":"Horng"}],"publist_id":"4195","extern":1,"date_updated":"2021-01-12T06:59:09Z","citation":{"chicago":"Erdös, László, Benjamin Schlein, and Horng Yau. “Wegner Estimate and Level Repulsion for Wigner Random Matrices.” International Mathematics Research Notices. Oxford University Press, 2010. https://doi.org/10.1093/imrn/rnp136.","ista":"Erdös L, Schlein B, Yau H. 2010. Wegner estimate and level repulsion for Wigner random matrices. International Mathematics Research Notices. (3), 436–479.","mla":"Erdös, László, et al. “Wegner Estimate and Level Repulsion for Wigner Random Matrices.” International Mathematics Research Notices, no. 3, Oxford University Press, 2010, pp. 436–79, doi:10.1093/imrn/rnp136.","ieee":"L. Erdös, B. Schlein, and H. Yau, “Wegner estimate and level repulsion for Wigner random matrices,” International Mathematics Research Notices, no. 3. Oxford University Press, pp. 436–479, 2010.","short":"L. Erdös, B. Schlein, H. Yau, International Mathematics Research Notices (2010) 436–479.","apa":"Erdös, L., Schlein, B., & Yau, H. (2010). Wegner estimate and level repulsion for Wigner random matrices. International Mathematics Research Notices. Oxford University Press. https://doi.org/10.1093/imrn/rnp136","ama":"Erdös L, Schlein B, Yau H. Wegner estimate and level repulsion for Wigner random matrices. International Mathematics Research Notices. 2010;(3):436-479. doi:10.1093/imrn/rnp136"},"status":"public","type":"journal_article","_id":"2701","date_created":"2018-12-11T11:59:09Z","doi":"10.1093/imrn/rnp136","issue":"3","date_published":"2010-01-01T00:00:00Z","page":"436 - 479","publication":"International Mathematics Research Notices","day":"01","year":"2010","publication_status":"published","month":"01","main_file_link":[{"open_access":"1","url":"http://arxiv.org/abs/0811.2591"}],"oa":1,"quality_controlled":0,"publisher":"Oxford University Press","abstract":[{"text":"We consider N × N Hermitian random matrices with independent identically distributed entries (Wigner matrices). The matrices are normalized so that the average spacing between consecutive eigenvalues is of order 1/ N. Under suitable assumptions on the distribution of the single matrix element, we first prove that, away from the spectral edges, the empirical density of eigenvalues concentrates around the Wigner semicircle law on energy scales η ≫ N -1. This result establishes the semicircle law on the optimal scale and it removes a logarithmic factor from our previous result [6]. We then show a Wegner estimate, i.e., that the averaged density of states is bounded. Finally, we prove that the eigenvalues of a Wigner matrix repel each other, in agreement with the universality conjecture.","lang":"eng"}]},{"publication_status":"published","year":"2010","publication":"Communications on Pure and Applied Mathematics","day":"01","page":"895 - 925","date_created":"2018-12-11T11:59:28Z","volume":63,"issue":"7","date_published":"2010-07-01T00:00:00Z","doi":"10.1002/cpa.20317","abstract":[{"lang":"eng","text":"We consider N ×N Hermitian Wigner random matrices H where the probabilitydensity for each matrix element is given by the density v(x)=e-U(x). We prove that the eigenvalue statistics in the bulk are given by the Dyson sine kernel provided that U ∈ C 6(R{double-struck}) with at most polynomially growing derivatives and v(x)≤C e-c(x) for x large. The proof is based upon an approximate time reversal of the Dyson Brownian motion combined with the convergence of the eigenvalue density to the Wigner semicircle law on short scales."}],"quality_controlled":0,"publisher":"Wiley-Blackwell","intvolume":" 63","month":"07","date_updated":"2021-01-12T06:59:32Z","citation":{"chicago":"Erdös, László, José Ramírez, Horng Yau, Sandrine Péché, and Benjamin Schlein. “Bulk Universality for Wigner Matrices.” Communications on Pure and Applied Mathematics. Wiley-Blackwell, 2010. https://doi.org/10.1002/cpa.20317.","ista":"Erdös L, Ramírez J, Yau H, Péché S, Schlein B. 2010. Bulk universality for Wigner matrices. Communications on Pure and Applied Mathematics. 63(7), 895–925.","mla":"Erdös, László, et al. “Bulk Universality for Wigner Matrices.” Communications on Pure and Applied Mathematics, vol. 63, no. 7, Wiley-Blackwell, 2010, pp. 895–925, doi:10.1002/cpa.20317.","ieee":"L. Erdös, J. Ramírez, H. Yau, S. Péché, and B. Schlein, “Bulk universality for Wigner matrices,” Communications on Pure and Applied Mathematics, vol. 63, no. 7. Wiley-Blackwell, pp. 895–925, 2010.","short":"L. Erdös, J. Ramírez, H. Yau, S. Péché, B. Schlein, Communications on Pure and Applied Mathematics 63 (2010) 895–925.","ama":"Erdös L, Ramírez J, Yau H, Péché S, Schlein B. Bulk universality for Wigner matrices. Communications on Pure and Applied Mathematics. 2010;63(7):895-925. doi:10.1002/cpa.20317","apa":"Erdös, L., Ramírez, J., Yau, H., Péché, S., & Schlein, B. (2010). Bulk universality for Wigner matrices. Communications on Pure and Applied Mathematics. Wiley-Blackwell. https://doi.org/10.1002/cpa.20317"},"extern":1,"publist_id":"4130","author":[{"last_name":"Erdös","orcid":"0000-0001-5366-9603","full_name":"László Erdös","first_name":"László","id":"4DBD5372-F248-11E8-B48F-1D18A9856A87"},{"last_name":"Ramírez","full_name":"Ramírez, José A","first_name":"José"},{"first_name":"Horng","last_name":"Yau","full_name":"Yau, Horng-Tzer"},{"last_name":"Péché","full_name":"Péché, Sandrine","first_name":"Sandrine"},{"full_name":"Schlein, Benjamin","last_name":"Schlein","first_name":"Benjamin"}],"title":"Bulk universality for Wigner matrices","_id":"2762","type":"journal_article","status":"public"},{"abstract":[{"text":"We consider N × N Hermitian random matrices with independent identically distributed entries (Wigner matrices). We assume that the distribution of the entries have a Gaussian component with variance N 3/4+β for some positive β > 0. We prove that the local eigenvalue statistics follows the universal Dyson sine kernel.","lang":"eng"}],"intvolume":" 15","month":"01","publisher":"Institute of Mathematical Statistics","quality_controlled":0,"publication":"Electronic Journal of Probability","day":"01","year":"2010","publication_status":"published","date_created":"2018-12-11T11:59:27Z","issue":"18","doi":"10.1214/EJP.v15-768","volume":15,"date_published":"2010-01-01T00:00:00Z","page":"526 - 603","_id":"2761","status":"public","tmp":{"legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode","image":"/images/cc_by.png","name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)","short":"CC BY (4.0)"},"type":"journal_article","extern":1,"citation":{"short":"L. Erdös, J. Ramírez, B. Schlein, H. Yau, Electronic Journal of Probability 15 (2010) 526–603.","ieee":"L. Erdös, J. Ramírez, B. Schlein, and H. Yau, “Universality of sine-kernel for Wigner matrices with a small Gaussian perturbation,” Electronic Journal of Probability, vol. 15, no. 18. Institute of Mathematical Statistics, pp. 526–603, 2010.","ama":"Erdös L, Ramírez J, Schlein B, Yau H. Universality of sine-kernel for Wigner matrices with a small Gaussian perturbation. Electronic Journal of Probability. 2010;15(18):526-603. doi:10.1214/EJP.v15-768","apa":"Erdös, L., Ramírez, J., Schlein, B., & Yau, H. (2010). Universality of sine-kernel for Wigner matrices with a small Gaussian perturbation. Electronic Journal of Probability. Institute of Mathematical Statistics. https://doi.org/10.1214/EJP.v15-768","mla":"Erdös, László, et al. “Universality of Sine-Kernel for Wigner Matrices with a Small Gaussian Perturbation.” Electronic Journal of Probability, vol. 15, no. 18, Institute of Mathematical Statistics, 2010, pp. 526–603, doi:10.1214/EJP.v15-768.","ista":"Erdös L, Ramírez J, Schlein B, Yau H. 2010. Universality of sine-kernel for Wigner matrices with a small Gaussian perturbation. Electronic Journal of Probability. 15(18), 526–603.","chicago":"Erdös, László, José Ramírez, Benjamin Schlein, and Horng Yau. “Universality of Sine-Kernel for Wigner Matrices with a Small Gaussian Perturbation.” Electronic Journal of Probability. Institute of Mathematical Statistics, 2010. https://doi.org/10.1214/EJP.v15-768."},"date_updated":"2021-01-12T06:59:31Z","title":"Universality of sine-kernel for Wigner matrices with a small Gaussian perturbation","author":[{"last_name":"Erdös","orcid":"0000-0001-5366-9603","full_name":"László Erdös","id":"4DBD5372-F248-11E8-B48F-1D18A9856A87","first_name":"László"},{"last_name":"Ramírez","full_name":"Ramírez, José A","first_name":"José"},{"first_name":"Benjamin","full_name":"Schlein, Benjamin","last_name":"Schlein"},{"full_name":"Yau, Horng-Tzer","last_name":"Yau","first_name":"Horng"}],"publist_id":"4131"},{"title":"Ground state energy of large atoms in a self-generated magnetic field","author":[{"last_name":"Erdös","full_name":"László Erdös","orcid":"0000-0001-5366-9603","first_name":"László","id":"4DBD5372-F248-11E8-B48F-1D18A9856A87"},{"full_name":"Solovej, Jan P","last_name":"Solovej","first_name":"Jan"}],"publist_id":"4136","extern":1,"date_updated":"2021-01-12T06:59:29Z","citation":{"ista":"Erdös L, Solovej J. 2010. Ground state energy of large atoms in a self-generated magnetic field. Communications in Mathematical Physics. 294(1), 229–249.","chicago":"Erdös, László, and Jan Solovej. “Ground State Energy of Large Atoms in a Self-Generated Magnetic Field.” Communications in Mathematical Physics. Springer, 2010. https://doi.org/10.1007/s00220-009-0869-2.","ama":"Erdös L, Solovej J. Ground state energy of large atoms in a self-generated magnetic field. Communications in Mathematical Physics. 2010;294(1):229-249. doi:10.1007/s00220-009-0869-2","apa":"Erdös, L., & Solovej, J. (2010). Ground state energy of large atoms in a self-generated magnetic field. Communications in Mathematical Physics. Springer. https://doi.org/10.1007/s00220-009-0869-2","ieee":"L. Erdös and J. Solovej, “Ground state energy of large atoms in a self-generated magnetic field,” Communications in Mathematical Physics, vol. 294, no. 1. Springer, pp. 229–249, 2010.","short":"L. Erdös, J. Solovej, Communications in Mathematical Physics 294 (2010) 229–249.","mla":"Erdös, László, and Jan Solovej. “Ground State Energy of Large Atoms in a Self-Generated Magnetic Field.” Communications in Mathematical Physics, vol. 294, no. 1, Springer, 2010, pp. 229–49, doi:10.1007/s00220-009-0869-2."},"status":"public","type":"journal_article","_id":"2756","date_created":"2018-12-11T11:59:26Z","doi":"10.1007/s00220-009-0869-2","date_published":"2010-02-01T00:00:00Z","volume":294,"issue":"1","page":"229 - 249","publication":"Communications in Mathematical Physics","day":"01","year":"2010","publication_status":"published","intvolume":" 294","month":"02","publisher":"Springer","quality_controlled":0,"abstract":[{"lang":"eng","text":"We consider a large atom with nuclear charge Z described by non-relativistic quantum mechanics with classical or quantized electromagnetic field. We prove that the absolute ground state energy, allowing for minimizing over all possible self-generated electromagnetic fields, is given by the non-magnetic Thomas-Fermi theory to leading order in the simultaneous Z → ∞, α → 0 limit if Zα2 ≤ κ for some universal κ, where α is the fine structure constant."}]},{"status":"public","type":"journal_article","_id":"2763","title":"Bulk universality for Wigner Hermitian matrices with subexponential decay","publist_id":"4129","author":[{"last_name":"Erdös","full_name":"László Erdös","orcid":"0000-0001-5366-9603","id":"4DBD5372-F248-11E8-B48F-1D18A9856A87","first_name":"László"},{"full_name":"Ramírez, José A","last_name":"Ramírez","first_name":"José"},{"first_name":"Benjamin","full_name":"Schlein, Benjamin","last_name":"Schlein"},{"full_name":"Tao, Terence","last_name":"Tao","first_name":"Terence"},{"first_name":"Vu","last_name":"Van","full_name":"Van, Vu"},{"full_name":"Yau, Horng-Tzer","last_name":"Yau","first_name":"Horng"}],"extern":1,"date_updated":"2021-01-12T06:59:32Z","citation":{"ista":"Erdös L, Ramírez J, Schlein B, Tao T, Van V, Yau H. 2010. Bulk universality for Wigner Hermitian matrices with subexponential decay. Mathematical Research Letters. 17(4), 667–674.","chicago":"Erdös, László, José Ramírez, Benjamin Schlein, Terence Tao, Vu Van, and Horng Yau. “Bulk Universality for Wigner Hermitian Matrices with Subexponential Decay.” Mathematical Research Letters. International Press, 2010.","ieee":"L. Erdös, J. Ramírez, B. Schlein, T. Tao, V. Van, and H. Yau, “Bulk universality for Wigner Hermitian matrices with subexponential decay,” Mathematical Research Letters, vol. 17, no. 4. International Press, pp. 667–674, 2010.","short":"L. Erdös, J. Ramírez, B. Schlein, T. Tao, V. Van, H. Yau, Mathematical Research Letters 17 (2010) 667–674.","ama":"Erdös L, Ramírez J, Schlein B, Tao T, Van V, Yau H. Bulk universality for Wigner Hermitian matrices with subexponential decay. Mathematical Research Letters. 2010;17(4):667-674.","apa":"Erdös, L., Ramírez, J., Schlein, B., Tao, T., Van, V., & Yau, H. (2010). Bulk universality for Wigner Hermitian matrices with subexponential decay. Mathematical Research Letters. International Press.","mla":"Erdös, László, et al. “Bulk Universality for Wigner Hermitian Matrices with Subexponential Decay.” Mathematical Research Letters, vol. 17, no. 4, International Press, 2010, pp. 667–74."},"month":"07","intvolume":" 17","quality_controlled":0,"publisher":"International Press","abstract":[{"text":"In this paper, we consider the ensemble of n×n Wigner Hermitian matrices H = (hℓk)1≤ℓ,k≤n that generalize the Gaussian unitary ensemble (GUE). The matrix elements hℓk = h̄ℓk are given by hℓk = n ?1/2(xℓk + √?1yℓk), where xℓk, yℓk for 1 ≤ ℓ < k ≤ n are i.i.d. random variables with mean zero and variance 1/2, yℓ ℓ = 0 and xℓ ℓ have mean zero and variance 1. We assume the distribution of xℓk, yℓk to have subexponential decay. In [3], four of the authors recently established that the gap distribution and averaged k-point correlation of these matrices were universal (and in particular, agreed with those for GUE) assuming additional regularity hypotheses on the xℓk, yℓk. In [7], the other two authors, using a different method, established the same conclusion assuming instead some moment and support conditions on the xℓk, yℓk. In this short note we observe that the arguments of [3] and [7] can be combined to establish universality of the gap distribution and averaged k-point correlations for all Wigner matrices (with subexponentially decaying entries), with no extra assumptions.","lang":"eng"}],"issue":"4","volume":17,"date_published":"2010-07-01T00:00:00Z","date_created":"2018-12-11T11:59:28Z","page":"667 - 674","day":"01","publication":"Mathematical Research Letters","publication_status":"published","year":"2010"},{"publist_id":"4091","author":[{"last_name":"Hof","orcid":"0000-0003-2057-2754","full_name":"Björn Hof","first_name":"Björn","id":"3A374330-F248-11E8-B48F-1D18A9856A87"},{"last_name":"De Lózar","full_name":"de Lózar, Alberto","first_name":"Alberto"},{"first_name":"Marc","last_name":"Avila","full_name":"Avila, Marc"},{"first_name":"Xiaoyun","id":"2AFD1610-F248-11E8-B48F-1D18A9856A87","last_name":"Tu","full_name":"Xiaoyun Tu"},{"full_name":"Schneider, Tobias M","last_name":"Schneider","first_name":"Tobias"}],"title":"Eliminating turbulence in spatially intermittent flows","citation":{"ista":"Hof B, De Lózar A, Avila M, Tu X, Schneider T. 2010. Eliminating turbulence in spatially intermittent flows. Science. 327(5972), 1491–1494.","chicago":"Hof, Björn, Alberto De Lózar, Marc Avila, Xiaoyun Tu, and Tobias Schneider. “Eliminating Turbulence in Spatially Intermittent Flows.” Science. American Association for the Advancement of Science, 2010. https://doi.org/10.1126/science.1186091.","short":"B. Hof, A. De Lózar, M. Avila, X. Tu, T. Schneider, Science 327 (2010) 1491–1494.","ieee":"B. Hof, A. De Lózar, M. Avila, X. Tu, and T. Schneider, “Eliminating turbulence in spatially intermittent flows,” Science, vol. 327, no. 5972. American Association for the Advancement of Science, pp. 1491–1494, 2010.","apa":"Hof, B., De Lózar, A., Avila, M., Tu, X., & Schneider, T. (2010). Eliminating turbulence in spatially intermittent flows. Science. American Association for the Advancement of Science. https://doi.org/10.1126/science.1186091","ama":"Hof B, De Lózar A, Avila M, Tu X, Schneider T. Eliminating turbulence in spatially intermittent flows. Science. 2010;327(5972):1491-1494. doi:10.1126/science.1186091","mla":"Hof, Björn, et al. “Eliminating Turbulence in Spatially Intermittent Flows.” Science, vol. 327, no. 5972, American Association for the Advancement of Science, 2010, pp. 1491–94, doi:10.1126/science.1186091."},"date_updated":"2021-01-12T06:59:47Z","extern":1,"type":"journal_article","status":"public","_id":"2798","page":"1491 - 1494","date_created":"2018-12-11T11:59:39Z","issue":"5972","doi":"10.1126/science.1186091","date_published":"2010-03-19T00:00:00Z","volume":327,"publication_status":"published","year":"2010","publication":"Science","day":"19","quality_controlled":0,"publisher":"American Association for the Advancement of Science","intvolume":" 327","month":"03","abstract":[{"lang":"eng","text":"Flows through pipes and channels are the most common means to transport fluids in practical applications and equally occur in numerous natural systems. In general, the transfer of fluids is energetically far more efficient if the motion is smooth and laminar because the friction losses are lower. However, even at moderate velocities pipe and channel flows are sensitive to minute disturbances, and in practice most flows are turbulent. Investigating the motion and spatial distribution of vortices, we uncovered an amplification mechanism that constantly feeds energy from the mean shear into turbulent eddies. At intermediate flow rates, a simple control mechanism suffices to intercept this energy transfer by reducing inflection points in the velocity profile. When activated, an immediate collapse of turbulence is observed, and the flow relaminarizes."}]},{"title":"The auxin influx carriers AUX1 and LAX3 are involved in auxin-ethylene interactions during apical hook development in Arabidopsis thaliana seedlings","publist_id":"3898","author":[{"last_name":"Vandenbussche","full_name":"Vandenbussche, Filip","first_name":"Filip"},{"last_name":"Petrášek","full_name":"Petrášek, Jan","first_name":"Jan"},{"first_name":"Petra","last_name":"Žádníková","full_name":"Žádníková, Petra"},{"first_name":"Klára","full_name":"Hoyerová, Klára","last_name":"Hoyerová"},{"full_name":"Pešek, Bedřich","last_name":"Pešek","first_name":"Bedřich"},{"full_name":"Raz, Vered","last_name":"Raz","first_name":"Vered"},{"first_name":"Ranjan","last_name":"Swarup","full_name":"Swarup, Ranjan"},{"first_name":"Malcolm","last_name":"Bennett","full_name":"Bennett, Malcolm"},{"full_name":"Zažímalová, Eva","last_name":"Zažímalová","first_name":"Eva"},{"id":"38F4F166-F248-11E8-B48F-1D18A9856A87","first_name":"Eva","last_name":"Benková","full_name":"Eva Benková","orcid":"0000-0002-8510-9739"},{"full_name":"Van Der Straeten, Dominique","last_name":"Van Der Straeten","first_name":"Dominique"}],"extern":1,"citation":{"chicago":"Vandenbussche, Filip, Jan Petrášek, Petra Žádníková, Klára Hoyerová, Bedřich Pešek, Vered Raz, Ranjan Swarup, et al. “The Auxin Influx Carriers AUX1 and LAX3 Are Involved in Auxin-Ethylene Interactions during Apical Hook Development in Arabidopsis Thaliana Seedlings.” Development. Company of Biologists, 2010. https://doi.org/10.1242/dev.040790.","ista":"Vandenbussche F, Petrášek J, Žádníková P, Hoyerová K, Pešek B, Raz V, Swarup R, Bennett M, Zažímalová E, Benková E, Van Der Straeten D. 2010. The auxin influx carriers AUX1 and LAX3 are involved in auxin-ethylene interactions during apical hook development in Arabidopsis thaliana seedlings. Development. 137(4), 597–606.","mla":"Vandenbussche, Filip, et al. “The Auxin Influx Carriers AUX1 and LAX3 Are Involved in Auxin-Ethylene Interactions during Apical Hook Development in Arabidopsis Thaliana Seedlings.” Development, vol. 137, no. 4, Company of Biologists, 2010, pp. 597–606, doi:10.1242/dev.040790.","ama":"Vandenbussche F, Petrášek J, Žádníková P, et al. The auxin influx carriers AUX1 and LAX3 are involved in auxin-ethylene interactions during apical hook development in Arabidopsis thaliana seedlings. Development. 2010;137(4):597-606. doi:10.1242/dev.040790","apa":"Vandenbussche, F., Petrášek, J., Žádníková, P., Hoyerová, K., Pešek, B., Raz, V., … Van Der Straeten, D. (2010). The auxin influx carriers AUX1 and LAX3 are involved in auxin-ethylene interactions during apical hook development in Arabidopsis thaliana seedlings. Development. Company of Biologists. https://doi.org/10.1242/dev.040790","short":"F. Vandenbussche, J. Petrášek, P. Žádníková, K. Hoyerová, B. Pešek, V. Raz, R. Swarup, M. Bennett, E. Zažímalová, E. Benková, D. Van Der Straeten, Development 137 (2010) 597–606.","ieee":"F. Vandenbussche et al., “The auxin influx carriers AUX1 and LAX3 are involved in auxin-ethylene interactions during apical hook development in Arabidopsis thaliana seedlings,” Development, vol. 137, no. 4. Company of Biologists, pp. 597–606, 2010."},"date_updated":"2021-01-12T07:00:23Z","status":"public","type":"journal_article","_id":"2870","date_created":"2018-12-11T12:00:02Z","volume":137,"doi":"10.1242/dev.040790","issue":"4","date_published":"2010-02-15T00:00:00Z","page":"597 - 606","publication":"Development","day":"15","year":"2010","publication_status":"published","intvolume":" 137","month":"02","quality_controlled":0,"publisher":"Company of Biologists","abstract":[{"lang":"eng","text":"Dark-grown dicotyledonous seedlings form a hook-like structure at the top of the hypocotyl, which is controlled by the hormones auxin and ethylene. Hook formation is dependent on an auxin signal gradient, whereas hook exaggeration is part of the triple response provoked by ethylene in dark-grown Arabidopsis seedlings. Several other hormones and light are also known to be involved in hook development, but the molecular mechanisms that lead to the initial installation of an auxin gradient are still poorly understood. In this study, we aimed to unravel the cross-talk between auxin and ethylene in the apical hook. Auxin measurements, the expression pattern of the auxin reporter DR5::GUS and the localization of auxin biosynthesis enzymes and influx carriers collectively indicate the necessity for auxin biosynthesis and efficient auxin translocation from the cotyledons and meristem into the hypocotyl in order to support proper hook development. Auxin accumulation in the meristem and cotyledons and in the hypocotyl is increased ∼2-fold upon treatment with ethylene. In addition, a strong ethylene signal leads to enhanced auxin biosynthesis at the inner side of the hook. Finally, mutant analysis demonstrates that the auxin influx carrier LAX3 is indispensable for proper hook formation, whereas the auxin influx carrier AUX1 is involved in the hook exaggeration phenotype induced by ethylene."}]},{"publist_id":"3896","author":[{"last_name":"Krouk","full_name":"Krouk, Gabriel","first_name":"Gabriel"},{"first_name":"Benoît","full_name":"Lacombe, Benoît","last_name":"Lacombe"},{"last_name":"Bielach","full_name":"Bielach, Agnieszka","first_name":"Agnieszka"},{"first_name":"Francine","last_name":"Perrine Walker","full_name":"Perrine-Walker, Francine"},{"full_name":"Malínská, Kateřina","last_name":"Malínská","first_name":"Kateřina"},{"last_name":"Mounier","full_name":"Mounier, Emmanuelle","first_name":"Emmanuelle"},{"first_name":"Klára","full_name":"Hoyerová, Klára","last_name":"Hoyerová"},{"first_name":"Pascal","last_name":"Tillard","full_name":"Tillard, Pascal"},{"last_name":"Leon","full_name":"Leon, Sarah","first_name":"Sarah"},{"first_name":"Karin","full_name":"Ljung, Karin","last_name":"Ljung"},{"first_name":"Eva","full_name":"Zažímalová, Eva","last_name":"Zažímalová"},{"orcid":"0000-0002-8510-9739","full_name":"Eva Benková","last_name":"Benková","id":"38F4F166-F248-11E8-B48F-1D18A9856A87","first_name":"Eva"},{"first_name":"Philippe","last_name":"Nacry","full_name":"Nacry, Philippe"},{"first_name":"Alain","full_name":"Gojon, Alain","last_name":"Gojon"}],"title":"Nitrate-regulated auxin transport by NRT1.1 defines a mechanism for nutrient sensing in plants","date_updated":"2021-01-12T07:00:24Z","citation":{"ista":"Krouk G, Lacombe B, Bielach A, Perrine Walker F, Malínská K, Mounier E, Hoyerová K, Tillard P, Leon S, Ljung K, Zažímalová E, Benková E, Nacry P, Gojon A. 2010. Nitrate-regulated auxin transport by NRT1.1 defines a mechanism for nutrient sensing in plants. Developmental Cell. 18(6), 927–937.","chicago":"Krouk, Gabriel, Benoît Lacombe, Agnieszka Bielach, Francine Perrine Walker, Kateřina Malínská, Emmanuelle Mounier, Klára Hoyerová, et al. “Nitrate-Regulated Auxin Transport by NRT1.1 Defines a Mechanism for Nutrient Sensing in Plants.” Developmental Cell. Cell Press, 2010. https://doi.org/10.1016/j.devcel.2010.05.008.","ieee":"G. Krouk et al., “Nitrate-regulated auxin transport by NRT1.1 defines a mechanism for nutrient sensing in plants,” Developmental Cell, vol. 18, no. 6. Cell Press, pp. 927–937, 2010.","short":"G. Krouk, B. Lacombe, A. Bielach, F. Perrine Walker, K. Malínská, E. Mounier, K. Hoyerová, P. Tillard, S. Leon, K. Ljung, E. Zažímalová, E. Benková, P. Nacry, A. Gojon, Developmental Cell 18 (2010) 927–937.","apa":"Krouk, G., Lacombe, B., Bielach, A., Perrine Walker, F., Malínská, K., Mounier, E., … Gojon, A. (2010). Nitrate-regulated auxin transport by NRT1.1 defines a mechanism for nutrient sensing in plants. Developmental Cell. Cell Press. https://doi.org/10.1016/j.devcel.2010.05.008","ama":"Krouk G, Lacombe B, Bielach A, et al. Nitrate-regulated auxin transport by NRT1.1 defines a mechanism for nutrient sensing in plants. Developmental Cell. 2010;18(6):927-937. doi:10.1016/j.devcel.2010.05.008","mla":"Krouk, Gabriel, et al. “Nitrate-Regulated Auxin Transport by NRT1.1 Defines a Mechanism for Nutrient Sensing in Plants.” Developmental Cell, vol. 18, no. 6, Cell Press, 2010, pp. 927–37, doi:10.1016/j.devcel.2010.05.008."},"extern":1,"type":"journal_article","status":"public","_id":"2873","page":"927 - 937","date_created":"2018-12-11T12:00:04Z","date_published":"2010-06-15T00:00:00Z","doi":"10.1016/j.devcel.2010.05.008","volume":18,"issue":"6","publication_status":"published","year":"2010","publication":"Developmental Cell","day":"15","quality_controlled":0,"publisher":"Cell Press","intvolume":" 18","month":"06","abstract":[{"lang":"eng","text":"Nitrate is both a nitrogen source for higher plants and a signal molecule regulating their development. In Arabidopsis, the NRT1.1 nitrate transporter is crucial for nitrate signaling governing root growth, and has been proposed to act as a nitrate sensor. However, the sensing mechanism is unknown. Herein we show that NRT1.1 not only transports nitrate but also facilitates uptake of the phytohormone auxin. Moreover, nitrate inhibits NRT1.1-dependent auxin uptake, suggesting that transduction of nitrate signal by NRT1.1 is associated with a modification of auxin transport. Among other effects, auxin stimulates lateral root development. Mutation of NRT1.1 enhances both auxin accumulation in lateral roots and growth of these roots at low, but not high, nitrate concentration. Thus, we propose that NRT1.1 represses lateral root growth at low nitrate availability by promoting basipetal auxin transport out of these roots. This defines a mechanism connecting nutrient and hormone signaling during organ development."}]},{"abstract":[{"text":"Unlike locomotive organisms capable of actively approaching essential resources, sessile plants must efficiently exploit their habitat for water and nutrients. This involves root-mediated underground interactions allowing plants to adapt to soils of diverse qualities. The root system of plants is a dynamic structure that modulates primary root growth and root branching by continuous integration of environmental inputs, such as nutrition availability, soil aeration, humidity, or salinity. Root branching is an extremely flexible means to rapidly adjust the overall surface of the root system and plants have evolved efficient control mechanisms, including, firstly initiation, when and where to start lateral root formation; secondly lateral root primordia organogenesis, during which the development of primordia can be arrested for a certain time; and thirdly lateral root emergence. Our review will focus on the most recent advances in understanding the molecular mechanisms involved in the regulation of lateral root initiation and organogenesis with the main focus on root system of the model plant Arabidopsis thaliana.","lang":"eng"}],"quality_controlled":0,"publisher":"Elsevier","intvolume":" 13","month":"12","year":"2010","publication_status":"published","publication":"Current Opinion in Plant Biology","day":"01","page":"677 - 683","date_created":"2018-12-11T12:00:03Z","issue":"6","date_published":"2010-12-01T00:00:00Z","volume":13,"doi":"10.1016/j.pbi.2010.09.006","_id":"2872","type":"journal_article","status":"public","date_updated":"2021-01-12T07:00:24Z","citation":{"chicago":"Benková, Eva, and Agnieszka Bielach. “Lateral Root Organogenesis - from Cell to Organ.” Current Opinion in Plant Biology. Elsevier, 2010. https://doi.org/10.1016/j.pbi.2010.09.006.","ista":"Benková E, Bielach A. 2010. Lateral root organogenesis - from cell to organ. Current Opinion in Plant Biology. 13(6), 677–683.","mla":"Benková, Eva, and Agnieszka Bielach. “Lateral Root Organogenesis - from Cell to Organ.” Current Opinion in Plant Biology, vol. 13, no. 6, Elsevier, 2010, pp. 677–83, doi:10.1016/j.pbi.2010.09.006.","ama":"Benková E, Bielach A. Lateral root organogenesis - from cell to organ. Current Opinion in Plant Biology. 2010;13(6):677-683. doi:10.1016/j.pbi.2010.09.006","apa":"Benková, E., & Bielach, A. (2010). Lateral root organogenesis - from cell to organ. Current Opinion in Plant Biology. Elsevier. https://doi.org/10.1016/j.pbi.2010.09.006","ieee":"E. Benková and A. Bielach, “Lateral root organogenesis - from cell to organ,” Current Opinion in Plant Biology, vol. 13, no. 6. Elsevier, pp. 677–683, 2010.","short":"E. Benková, A. Bielach, Current Opinion in Plant Biology 13 (2010) 677–683."},"extern":1,"publist_id":"3895","author":[{"full_name":"Eva Benková","orcid":"0000-0002-8510-9739","last_name":"Benková","first_name":"Eva","id":"38F4F166-F248-11E8-B48F-1D18A9856A87"},{"full_name":"Bielach, Agnieszka","last_name":"Bielach","first_name":"Agnieszka"}],"title":"Lateral root organogenesis - from cell to organ"}]