--- _id: '2791' abstract: - lang: eng text: Generally, the motion of fluids is smooth and laminar at low speeds but becomes highly disordered and turbulent as the velocity increases. The transition from laminar to turbulent flow can involve a sequence of instabilities in which the system realizes progressively more complicated states, or it can occur suddenly. Once the transition has taken place, it is generally assumed that, under steady conditions, the turbulent state will persist indefinitely. The flow of a fluid down a straight pipe provides a ubiquitous example of a shear flow undergoing a sudden transition from laminar to turbulent motion. Extensive calculations and experimental studies have shown that, at relatively low flow rates, turbulence in pipes is transient, and is characterized by an exponential distribution of lifetimes. They also suggest that for Reynolds numbers exceeding a critical value the lifetime diverges (that is, becomes infinitely large), marking a change from transient to persistent turbulence. Here we present experimental data and numerical calculations covering more than two decades of lifetimes, showing that the lifetime does not in fact diverge but rather increases exponentially with the Reynolds number. This implies that turbulence in pipes is only a transient event (contrary to the commonly accepted view), and that the turbulent and laminar states remain dynamically connected, suggesting avenues for turbulence control. author: - first_name: Björn full_name: Björn Hof id: 3A374330-F248-11E8-B48F-1D18A9856A87 last_name: Hof orcid: 0000-0003-2057-2754 - first_name: Jerry full_name: Westerweel, Jerry last_name: Westerweel - first_name: Tobias full_name: Schneider, Tobias M last_name: Schneider - first_name: Bruno full_name: Eckhardt, Bruno last_name: Eckhardt citation: ama: Hof B, Westerweel J, Schneider T, Eckhardt B. Finite lifetime of turbulence in shear flows. Nature. 2006;443(7107):59-62. doi:10.1038/nature05089 apa: Hof, B., Westerweel, J., Schneider, T., & Eckhardt, B. (2006). Finite lifetime of turbulence in shear flows. Nature. Nature Publishing Group. https://doi.org/10.1038/nature05089 chicago: Hof, Björn, Jerry Westerweel, Tobias Schneider, and Bruno Eckhardt. “Finite Lifetime of Turbulence in Shear Flows.” Nature. Nature Publishing Group, 2006. https://doi.org/10.1038/nature05089. ieee: B. Hof, J. Westerweel, T. Schneider, and B. Eckhardt, “Finite lifetime of turbulence in shear flows,” Nature, vol. 443, no. 7107. Nature Publishing Group, pp. 59–62, 2006. ista: Hof B, Westerweel J, Schneider T, Eckhardt B. 2006. Finite lifetime of turbulence in shear flows. Nature. 443(7107), 59–62. mla: Hof, Björn, et al. “Finite Lifetime of Turbulence in Shear Flows.” Nature, vol. 443, no. 7107, Nature Publishing Group, 2006, pp. 59–62, doi:10.1038/nature05089. short: B. Hof, J. Westerweel, T. Schneider, B. Eckhardt, Nature 443 (2006) 59–62. date_created: 2018-12-11T11:59:37Z date_published: 2006-09-07T00:00:00Z date_updated: 2021-01-12T06:59:44Z day: '07' doi: 10.1038/nature05089 extern: 1 intvolume: ' 443' issue: '7107' month: '09' page: 59 - 62 publication: Nature publication_status: published publisher: Nature Publishing Group publist_id: '4098' quality_controlled: 0 status: public title: Finite lifetime of turbulence in shear flows type: journal_article volume: 443 year: '2006' ... --- _id: '2792' abstract: - lang: eng text: Transition to turbulence in pipe flow has posed a riddle in fluid dynamics since the pioneering experiments of Reynolds[1]. Although the laminar flow is linearly stable for all flow rates, practical pipe flows become turbulent at large enough flow speeds. Turbulence arises suddenly and fully without distinct steps and without a clear critical point. The complexity of this problem has puzzled mathematicians, physicists and engineers for more than a century and no satisfactory explanation of this problem has been given. In a very recent theoretical approach it has been suggested that unstable solutions of the Navier Stokes equations may hold the key to understanding this problem. In numerical studies such unstable states have been identified as exact solutions for the idealized case of a pipe with periodic boundary conditions[2, 3]. These solutions have the form of waves extending through the entire pipe and travelling in the streamwise direction at a phase speed close to the bulk velocity of the fluid. With the aid of a recently developed high-speed stereoscopic Particle Image Velocimetry (PIV) system, we were able to observe transients of such unstable solutions in turbulent pipe flow[4]. author: - first_name: Björn full_name: Björn Hof id: 3A374330-F248-11E8-B48F-1D18A9856A87 last_name: Hof orcid: 0000-0003-2057-2754 - first_name: Casimir full_name: van Doorne, Casimir W last_name: Van Doorne - first_name: Jerry full_name: Westerweel, Jerry last_name: Westerweel - first_name: Frans full_name: Nieuwstadt, Frans T last_name: Nieuwstadt citation: ama: Hof B, Van Doorne C, Westerweel J, Nieuwstadt F. Observation of nonlinear travelling waves in turbulent pipe flow. Fluid Mechanics and its Applications. 2006;78:109-114. doi:10.1007/1-4020-4159-4_11 apa: Hof, B., Van Doorne, C., Westerweel, J., & Nieuwstadt, F. (2006). Observation of nonlinear travelling waves in turbulent pipe flow. Fluid Mechanics and Its Applications. Springer. https://doi.org/10.1007/1-4020-4159-4_11 chicago: Hof, Björn, Casimir Van Doorne, Jerry Westerweel, and Frans Nieuwstadt. “Observation of Nonlinear Travelling Waves in Turbulent Pipe Flow.” Fluid Mechanics and Its Applications. Springer, 2006. https://doi.org/10.1007/1-4020-4159-4_11. ieee: B. Hof, C. Van Doorne, J. Westerweel, and F. Nieuwstadt, “Observation of nonlinear travelling waves in turbulent pipe flow,” Fluid Mechanics and its Applications, vol. 78. Springer, pp. 109–114, 2006. ista: Hof B, Van Doorne C, Westerweel J, Nieuwstadt F. 2006. Observation of nonlinear travelling waves in turbulent pipe flow. Fluid Mechanics and its Applications. 78, 109–114. mla: Hof, Björn, et al. “Observation of Nonlinear Travelling Waves in Turbulent Pipe Flow.” Fluid Mechanics and Its Applications, vol. 78, Springer, 2006, pp. 109–14, doi:10.1007/1-4020-4159-4_11. short: B. Hof, C. Van Doorne, J. Westerweel, F. Nieuwstadt, Fluid Mechanics and Its Applications 78 (2006) 109–114. date_created: 2018-12-11T11:59:37Z date_published: 2006-01-18T00:00:00Z date_updated: 2021-01-12T06:59:45Z day: '18' doi: 10.1007/1-4020-4159-4_11 extern: 1 intvolume: ' 78' month: '01' page: 109 - 114 publication: Fluid Mechanics and its Applications publication_status: published publisher: Springer publist_id: '4097' quality_controlled: 0 status: public title: Observation of nonlinear travelling waves in turbulent pipe flow type: journal_article volume: 78 year: '2006' ... --- _id: '2894' abstract: - lang: eng text: IL-10 is a potent anti-inflammatory and immunomodulatory cytokine, exerting major effects in the degree and quality of the immune response. Using a newly generated IL-10 reporter mouse model, which easily allows the study of IL-10 expression from each allele in a single cell, we report here for the first time that IL-10 is predominantly monoallelic expressed in CD4+ T cells. Furthermore, we have compelling evidence that this expression pattern is not due to parental imprinting, allelic exclusion, or strong allelic bias. Instead, our results support a stochastic regulation mechanism, in which the probability to initiate allelic transcription depends on the strength of TCR signaling and subsequent capacity to overcome restrictions imposed by chromatin hypoacetylation. In vivo Ag-experienced T cells show a higher basal probability to transcribe IL-10 when compared with naive cells, yet still show mostly monoallelic IL-10 expression. Finally, statistical analysis on allelic expression data shows transcriptional independence between both alleles. We conclude that CD4+ T cells have a low probability for IL-10 allelic activation resulting in a predominantly monoallelic expression pattern, and that IL-10 expression appears to be stochastically regulated by controlling the frequency of expressing cells, rather than absolute protein levels per cell. author: - first_name: Dinis full_name: Calado, Dinis P last_name: Calado - first_name: Tiago full_name: Tiago Paixao id: 2C5658E6-F248-11E8-B48F-1D18A9856A87 last_name: Paixao orcid: 0000-0003-2361-3953 - first_name: Dan full_name: Holmberg, Dan last_name: Holmberg - first_name: Matthias full_name: Haury, Matthias last_name: Haury citation: ama: Calado D, Paixao T, Holmberg D, Haury M. Stochastic Monoallelic Expression of IL 10 in T Cells. Journal of Immunology. 2006;177(8):5358-5364. doi:10.4049/jimmunol.177.8.5358 apa: Calado, D., Paixao, T., Holmberg, D., & Haury, M. (2006). Stochastic Monoallelic Expression of IL 10 in T Cells. Journal of Immunology. American Association of Immunologists. https://doi.org/10.4049/jimmunol.177.8.5358 chicago: Calado, Dinis, Tiago Paixao, Dan Holmberg, and Matthias Haury. “Stochastic Monoallelic Expression of IL 10 in T Cells.” Journal of Immunology. American Association of Immunologists, 2006. https://doi.org/10.4049/jimmunol.177.8.5358 . ieee: D. Calado, T. Paixao, D. Holmberg, and M. Haury, “Stochastic Monoallelic Expression of IL 10 in T Cells,” Journal of Immunology, vol. 177, no. 8. American Association of Immunologists, pp. 5358–5364, 2006. ista: Calado D, Paixao T, Holmberg D, Haury M. 2006. Stochastic Monoallelic Expression of IL 10 in T Cells. Journal of Immunology. 177(8), 5358–5364. mla: Calado, Dinis, et al. “Stochastic Monoallelic Expression of IL 10 in T Cells.” Journal of Immunology, vol. 177, no. 8, American Association of Immunologists, 2006, pp. 5358–64, doi:10.4049/jimmunol.177.8.5358 . short: D. Calado, T. Paixao, D. Holmberg, M. Haury, Journal of Immunology 177 (2006) 5358–5364. date_created: 2018-12-11T12:00:11Z date_published: 2006-01-01T00:00:00Z date_updated: 2021-01-12T07:00:32Z day: '01' doi: '10.4049/jimmunol.177.8.5358 ' extern: 1 intvolume: ' 177' issue: '8' month: '01' page: 5358 - 5364 publication: Journal of Immunology publication_status: published publisher: American Association of Immunologists publist_id: '3864' quality_controlled: 0 status: public title: Stochastic Monoallelic Expression of IL 10 in T Cells type: journal_article volume: 177 year: '2006' ... --- _id: '2921' abstract: - lang: eng text: Most binocular stereo algorithms assume that all scene elements are visible from both cameras. Scene elements that are visible from only one camera, known as occlusions, pose an important challenge for stereo. Occlusions are important for segmentation, because they appear near discontinuities. However, stereo algorithms tend to ignore occlusions because of their difficulty. One reason is that occlusions require the input images to be treated symmetrically, which complicates the problem formulation. Worse, certain depth maps imply physically impossible scene configurations, and must be excluded from the output. In this chapter we approach the problem of binocular stereo with occlusions from an energy minimization viewpoint. We begin by reviewing traditional stereo methods that do not handle occlusions. If occlusions are ignored, it is easy to formulate the stereo problem as a pixel labeling problem, which leads to an energy function that is common in early vision. This kind of energy function can he minimized using graph cuts, which is a combinatorial optimization technique that has proven to be very effective for low-level vision problems. Motivated by this, we have designed two graph cut stereo algorithms that are designed to handle occlusions. These algorithms produce promising experimental results on real data with ground truth. author: - first_name: Vladimir full_name: Vladimir Kolmogorov id: 3D50B0BA-F248-11E8-B48F-1D18A9856A87 last_name: Kolmogorov - first_name: Ramin full_name: Zabih, Ramin last_name: Zabih citation: ama: 'Kolmogorov V, Zabih R. Graph cut algorithms for binocular stereo with occlusions. In: Handbook of Mathematical Models in Computer Vision. Springer; 2006:423-427. doi:10.1007/0-387-28831-7_26' apa: Kolmogorov, V., & Zabih, R. (2006). Graph cut algorithms for binocular stereo with occlusions. In Handbook of Mathematical Models in Computer Vision (pp. 423–427). Springer. https://doi.org/10.1007/0-387-28831-7_26 chicago: Kolmogorov, Vladimir, and Ramin Zabih. “Graph Cut Algorithms for Binocular Stereo with Occlusions.” In Handbook of Mathematical Models in Computer Vision, 423–27. Springer, 2006. https://doi.org/10.1007/0-387-28831-7_26. ieee: V. Kolmogorov and R. Zabih, “Graph cut algorithms for binocular stereo with occlusions,” in Handbook of Mathematical Models in Computer Vision, Springer, 2006, pp. 423–427. ista: 'Kolmogorov V, Zabih R. 2006.Graph cut algorithms for binocular stereo with occlusions. In: Handbook of Mathematical Models in Computer Vision. , 423–427.' mla: Kolmogorov, Vladimir, and Ramin Zabih. “Graph Cut Algorithms for Binocular Stereo with Occlusions.” Handbook of Mathematical Models in Computer Vision, Springer, 2006, pp. 423–27, doi:10.1007/0-387-28831-7_26. short: V. Kolmogorov, R. Zabih, in:, Handbook of Mathematical Models in Computer Vision, Springer, 2006, pp. 423–427. date_created: 2018-12-11T12:00:21Z date_published: 2006-01-01T00:00:00Z date_updated: 2021-01-12T07:00:42Z day: '01' doi: 10.1007/0-387-28831-7_26 extern: 1 month: '01' page: 423 - 427 publication: Handbook of Mathematical Models in Computer Vision publication_status: published publisher: Springer publist_id: '3816' quality_controlled: 0 status: public title: Graph cut algorithms for binocular stereo with occlusions type: book_chapter year: '2006' ... --- _id: '3002' abstract: - lang: eng text: Arabidopsis thaliana is currently the most important model organism for basic molecular plant research. It is also a favourable model for developmental biology, as its embryogenesis follows a nearly invariant pattern of cell divisions and cell type specifications. Study of embryogenesis can involve genetic, physiological or biochemical approaches, but is always limited by the inaccessibility of the embryos which develop deep inside maternal tissue. Thus, for developmental studies, there is an increasing demand for methods which allow embryogenesis under artificial conditions, providing better accessibility to experimental manipulation. In this chapter, we address theoretical aspects of embryo culture, give some thoughts on which embryo culture system is suited best for which application and finally discuss three current methods which have been successfully used in Arabidopsis embryo culture. © 2006 Springer-Verlag Berlin Heidelberg. alternative_title: - Plant Cell Monographs author: - first_name: Michael full_name: Sauer, Michael last_name: Sauer - first_name: Jirí full_name: Jirí Friml id: 4159519E-F248-11E8-B48F-1D18A9856A87 last_name: Friml orcid: 0000-0002-8302-7596 citation: ama: 'Sauer M, Friml J. In vitro culture of Arabidopsis embryos. In: Mujib A, Šamaj J, eds. Somatic Embryogenesis. Vol 2. Springer; 2006:343-354. doi:10.1007/7089_020' apa: Sauer, M., & Friml, J. (2006). In vitro culture of Arabidopsis embryos. In A. Mujib & J. Šamaj (Eds.), Somatic Embryogenesis (Vol. 2, pp. 343–354). Springer. https://doi.org/10.1007/7089_020 chicago: Sauer, Michael, and Jiří Friml. “In Vitro Culture of Arabidopsis Embryos.” In Somatic Embryogenesis, edited by Abdul Mujib and Jozef Šamaj, 2:343–54. Springer, 2006. https://doi.org/10.1007/7089_020. ieee: M. Sauer and J. Friml, “In vitro culture of Arabidopsis embryos,” in Somatic Embryogenesis, vol. 2, A. Mujib and J. Šamaj, Eds. Springer, 2006, pp. 343–354. ista: 'Sauer M, Friml J. 2006.In vitro culture of Arabidopsis embryos. In: Somatic Embryogenesis. Plant Cell Monographs, vol. 2, 343–354.' mla: Sauer, Michael, and Jiří Friml. “In Vitro Culture of Arabidopsis Embryos.” Somatic Embryogenesis, edited by Abdul Mujib and Jozef Šamaj, vol. 2, Springer, 2006, pp. 343–54, doi:10.1007/7089_020. short: M. Sauer, J. Friml, in:, A. Mujib, J. Šamaj (Eds.), Somatic Embryogenesis, Springer, 2006, pp. 343–354. date_created: 2018-12-11T12:00:48Z date_published: 2006-01-01T00:00:00Z date_updated: 2021-01-12T07:40:23Z day: '01' doi: 10.1007/7089_020 editor: - first_name: Abdul full_name: Mujib, Abdul last_name: Mujib - first_name: Jozef full_name: Šamaj, Jozef last_name: Šamaj extern: 1 intvolume: ' 2' month: '01' page: 343 - 354 publication: Somatic Embryogenesis publication_status: published publisher: Springer publist_id: '3699' quality_controlled: 0 status: public title: In vitro culture of Arabidopsis embryos type: book_chapter volume: 2 year: '2006' ... --- _id: '3012' abstract: - lang: eng text: Intercellular flow of the phytohormone auxin underpins multiple developmental processes in plants. Plant-specific pin-formed (PIN) proteins and several phosphoglycoprotein (PGP) transporters are crucial factors in auxin transport-related development, yet the molecular function of PINs remains unknown. Here, we show that PINs mediate auxin efflux from mammalian and yeast cells without needing additional plant-specific factors. Conditional gain-of-function alleles and quantitative measurements of auxin accumulation in Arabidopsis and tobacco cultured cells revealed that the action of PINs in auxin efflux is distinct from PGP, rate-limiting, specific to auxins, and sensitive to auxin transport inhibitors. This suggests a direct involvement of PINs in catalyzing cellular auxin efflux. author: - first_name: Jan full_name: Petrášek, Jan last_name: Petrášek - first_name: Jozef full_name: Mravec, Jozef last_name: Mravec - first_name: Rodolphe full_name: Bouchard, Rodolphe last_name: Bouchard - first_name: Joshua full_name: Blakeslee, Joshua last_name: Blakeslee - first_name: Melinda F full_name: Melinda Abas id: 3CFB3B1C-F248-11E8-B48F-1D18A9856A87 last_name: Abas - first_name: Daniela full_name: Seifertová, Daniela last_name: Seifertová - first_name: Justyna full_name: Wiśniewska, Justyna last_name: Wiśniewska - first_name: Zerihun full_name: Tadele, Zerihun last_name: Tadele - first_name: Martin full_name: Kubeš, Martin last_name: Kubeš - first_name: Milada full_name: Čovanová, Milada last_name: Čovanová - first_name: Pankaj full_name: Dhonukshe, Pankaj last_name: Dhonukshe - first_name: Petr full_name: Skůpa, Petr last_name: Skůpa - first_name: Eva full_name: Eva Benková id: 38F4F166-F248-11E8-B48F-1D18A9856A87 last_name: Benková orcid: 0000-0002-8510-9739 - first_name: Lucie full_name: Perry, Lucie last_name: Perry - first_name: Pavel full_name: Křeček, Pavel last_name: Křeček - first_name: Ok full_name: Lee, Ok Ran last_name: Lee - first_name: Gerald full_name: Fink, Gerald R last_name: Fink - first_name: Markus full_name: Geisler, Markus last_name: Geisler - first_name: Angus full_name: Murphy, Angus S last_name: Murphy - first_name: Christian full_name: Luschnig, Christian last_name: Luschnig - first_name: Eva full_name: Zažímalová, Eva last_name: Zažímalová - first_name: Jirí full_name: Jirí Friml id: 4159519E-F248-11E8-B48F-1D18A9856A87 last_name: Friml orcid: 0000-0002-8302-7596 citation: ama: Petrášek J, Mravec J, Bouchard R, et al. PIN proteins perform a rate-limiting function in cellular auxin efflux. Science. 2006;312(5775):914-918. doi:10.1126/science.1123542 apa: Petrášek, J., Mravec, J., Bouchard, R., Blakeslee, J., Abas, M. F., Seifertová, D., … Friml, J. (2006). PIN proteins perform a rate-limiting function in cellular auxin efflux. Science. American Association for the Advancement of Science. https://doi.org/10.1126/science.1123542 chicago: Petrášek, Jan, Jozef Mravec, Rodolphe Bouchard, Joshua Blakeslee, Melinda F Abas, Daniela Seifertová, Justyna Wiśniewska, et al. “PIN Proteins Perform a Rate-Limiting Function in Cellular Auxin Efflux.” Science. American Association for the Advancement of Science, 2006. https://doi.org/10.1126/science.1123542. ieee: J. Petrášek et al., “PIN proteins perform a rate-limiting function in cellular auxin efflux,” Science, vol. 312, no. 5775. American Association for the Advancement of Science, pp. 914–918, 2006. ista: Petrášek J, Mravec J, Bouchard R, Blakeslee J, Abas MF, Seifertová D, Wiśniewska J, Tadele Z, Kubeš M, Čovanová M, Dhonukshe P, Skůpa P, Benková E, Perry L, Křeček P, Lee O, Fink G, Geisler M, Murphy A, Luschnig C, Zažímalová E, Friml J. 2006. PIN proteins perform a rate-limiting function in cellular auxin efflux. Science. 312(5775), 914–918. mla: Petrášek, Jan, et al. “PIN Proteins Perform a Rate-Limiting Function in Cellular Auxin Efflux.” Science, vol. 312, no. 5775, American Association for the Advancement of Science, 2006, pp. 914–18, doi:10.1126/science.1123542. short: J. Petrášek, J. Mravec, R. Bouchard, J. Blakeslee, M.F. Abas, D. Seifertová, J. Wiśniewska, Z. Tadele, M. Kubeš, M. Čovanová, P. Dhonukshe, P. Skůpa, E. Benková, L. Perry, P. Křeček, O. Lee, G. Fink, M. Geisler, A. Murphy, C. Luschnig, E. Zažímalová, J. Friml, Science 312 (2006) 914–918. date_created: 2018-12-11T12:00:51Z date_published: 2006-05-12T00:00:00Z date_updated: 2021-01-12T07:40:27Z day: '12' doi: 10.1126/science.1123542 extern: 1 intvolume: ' 312' issue: '5775' month: '05' page: 914 - 918 publication: Science publication_status: published publisher: American Association for the Advancement of Science publist_id: '3690' quality_controlled: 0 status: public title: PIN proteins perform a rate-limiting function in cellular auxin efflux type: journal_article volume: 312 year: '2006' ... --- _id: '3010' abstract: - lang: eng text: The formation of the leaf vascular pattern has fascinated biologists for centuries. In the early leaf primordium, complex networks of procambial cells emerge from homogeneous subepidermal tissue. The molecular nature of the underlying positional information is unknown, but various lines of evidence implicate gradually restricted transport routes of the plant hormone auxin in defining sites of procambium formation. Here we show that a crucial member of the AtPIN family of auxin-efflux-associated proteins, AtPIN1, is expressed prior to pre-procambial and procambial cell fate markers in domains that become restricted toward sites of procambium formation. Subcellular AtPIN1 polarity indicates that auxin is directed to distinct "convergence points" in the epidermis, from where it defines the positions of major veins. Integrated polarities in all emerging veins indicate auxin drainage toward pre-existing veins, but veins display divergent polarities as they become connected at both ends. Auxin application and transport inhibition reveal that convergence point positioning and AtPIN1 expression domain dynamics are self-organizing, auxin-transport-dependent processes. We derive a model for self-regulated, reiterative patterning of all vein orders and postulate at its onset a common epidermal auxin-focusing mechanism for major-vein positioning and phyllotactic patterning. author: - first_name: Enrico full_name: Scarpella, Enrico last_name: Scarpella - first_name: Danielle full_name: Marcos, Danielle last_name: Marcos - first_name: Jirí full_name: Jirí Friml id: 4159519E-F248-11E8-B48F-1D18A9856A87 last_name: Friml orcid: 0000-0002-8302-7596 - first_name: Thomas full_name: Berleth, Thomas last_name: Berleth citation: ama: Scarpella E, Marcos D, Friml J, Berleth T. Control of leaf vascular patterning by polar auxin transport. Genes and Development. 2006;20(8):1015-1027. doi:10.1101/gad.1402406 apa: Scarpella, E., Marcos, D., Friml, J., & Berleth, T. (2006). Control of leaf vascular patterning by polar auxin transport. Genes and Development. Cold Spring Harbor Laboratory Press. https://doi.org/10.1101/gad.1402406 chicago: Scarpella, Enrico, Danielle Marcos, Jiří Friml, and Thomas Berleth. “Control of Leaf Vascular Patterning by Polar Auxin Transport.” Genes and Development. Cold Spring Harbor Laboratory Press, 2006. https://doi.org/10.1101/gad.1402406. ieee: E. Scarpella, D. Marcos, J. Friml, and T. Berleth, “Control of leaf vascular patterning by polar auxin transport,” Genes and Development, vol. 20, no. 8. Cold Spring Harbor Laboratory Press, pp. 1015–1027, 2006. ista: Scarpella E, Marcos D, Friml J, Berleth T. 2006. Control of leaf vascular patterning by polar auxin transport. Genes and Development. 20(8), 1015–1027. mla: Scarpella, Enrico, et al. “Control of Leaf Vascular Patterning by Polar Auxin Transport.” Genes and Development, vol. 20, no. 8, Cold Spring Harbor Laboratory Press, 2006, pp. 1015–27, doi:10.1101/gad.1402406. short: E. Scarpella, D. Marcos, J. Friml, T. Berleth, Genes and Development 20 (2006) 1015–1027. date_created: 2018-12-11T12:00:51Z date_published: 2006-04-15T00:00:00Z date_updated: 2021-01-12T07:40:26Z day: '15' doi: 10.1101/gad.1402406 extern: 1 intvolume: ' 20' issue: '8' month: '04' page: 1015 - 1027 publication: Genes and Development publication_status: published publisher: Cold Spring Harbor Laboratory Press publist_id: '3692' quality_controlled: 0 status: public title: Control of leaf vascular patterning by polar auxin transport type: journal_article volume: 20 year: '2006' ... --- _id: '3007' abstract: - lang: eng text: Root gravitropism describes the orientation of root growth along the gravity vector and is mediated by differential cell elongation in the root meristem. This response requires the coordinated, asymmetric distribution of the phytohormone auxin within the root meristem, and depends on the concerted activities of PIN proteins and AUX1 - members of the auxin transport pathway. Here, we show that intracellular trafficking and proteasome activity combine to control PIN2 degradation during root gravitropism. Following gravi-stimulation, proteasome-dependent variations in PIN2 localization and degradation at the upper and lower sides of the root result in asymmetric distribution of PIN2. Ubiquitination of PIN2 occurs in a proteasome-dependent manner, indicating that the proteasome is involved in the control of PIN2 turnover. Stabilization of PIN2 affects its abundance and distribution, and leads to defects in auxin distribution and gravitropic responses. We describe the effects of auxin on PIN2 localization and protein levels, indicating that redistribution of auxin during the gravitropic response may be involved in the regulation of PIN2 protein. author: - first_name: Lindy full_name: Abas, Lindy last_name: Abas - first_name: René full_name: Benjamins, René last_name: Benjamins - first_name: Nenad full_name: Malenica, Nenad last_name: Malenica - first_name: Tomasz full_name: Paciorek, Tomasz last_name: Paciorek - first_name: Justyna full_name: Wiśniewska, Justyna last_name: Wiśniewska - first_name: Jeanette full_name: Moulinier-Anzola, Jeanette C last_name: Moulinier Anzola - first_name: Tobias full_name: Sieberer, Tobias last_name: Sieberer - first_name: Jirí full_name: Jirí Friml id: 4159519E-F248-11E8-B48F-1D18A9856A87 last_name: Friml orcid: 0000-0002-8302-7596 - first_name: Christian full_name: Luschnig, Christian last_name: Luschnig citation: ama: Abas L, Benjamins R, Malenica N, et al. Intracellular trafficking and proteolysis of the Arabidopsis auxin-efflux facilitator PIN2 are involved in root gravitropism. Nature Cell Biology. 2006;8(3):249-256. doi:10.1038/ncb1369 apa: Abas, L., Benjamins, R., Malenica, N., Paciorek, T., Wiśniewska, J., Moulinier Anzola, J., … Luschnig, C. (2006). Intracellular trafficking and proteolysis of the Arabidopsis auxin-efflux facilitator PIN2 are involved in root gravitropism. Nature Cell Biology. Nature Publishing Group. https://doi.org/10.1038/ncb1369 chicago: Abas, Lindy, René Benjamins, Nenad Malenica, Tomasz Paciorek, Justyna Wiśniewska, Jeanette Moulinier Anzola, Tobias Sieberer, Jiří Friml, and Christian Luschnig. “Intracellular Trafficking and Proteolysis of the Arabidopsis Auxin-Efflux Facilitator PIN2 Are Involved in Root Gravitropism.” Nature Cell Biology. Nature Publishing Group, 2006. https://doi.org/10.1038/ncb1369. ieee: L. Abas et al., “Intracellular trafficking and proteolysis of the Arabidopsis auxin-efflux facilitator PIN2 are involved in root gravitropism,” Nature Cell Biology, vol. 8, no. 3. Nature Publishing Group, pp. 249–256, 2006. ista: Abas L, Benjamins R, Malenica N, Paciorek T, Wiśniewska J, Moulinier Anzola J, Sieberer T, Friml J, Luschnig C. 2006. Intracellular trafficking and proteolysis of the Arabidopsis auxin-efflux facilitator PIN2 are involved in root gravitropism. Nature Cell Biology. 8(3), 249–256. mla: Abas, Lindy, et al. “Intracellular Trafficking and Proteolysis of the Arabidopsis Auxin-Efflux Facilitator PIN2 Are Involved in Root Gravitropism.” Nature Cell Biology, vol. 8, no. 3, Nature Publishing Group, 2006, pp. 249–56, doi:10.1038/ncb1369. short: L. Abas, R. Benjamins, N. Malenica, T. Paciorek, J. Wiśniewska, J. Moulinier Anzola, T. Sieberer, J. Friml, C. Luschnig, Nature Cell Biology 8 (2006) 249–256. date_created: 2018-12-11T12:00:50Z date_published: 2006-03-01T00:00:00Z date_updated: 2021-01-12T07:40:25Z day: '01' doi: 10.1038/ncb1369 extern: 1 intvolume: ' 8' issue: '3' month: '03' page: 249 - 256 publication: Nature Cell Biology publication_status: published publisher: Nature Publishing Group publist_id: '3694' quality_controlled: 0 status: public title: Intracellular trafficking and proteolysis of the Arabidopsis auxin-efflux facilitator PIN2 are involved in root gravitropism type: journal_article volume: 8 year: '2006' ... --- _id: '3006' abstract: - lang: eng text: 'Dividing plant cells perform a remarkable task of building a new cell wall within the cytoplasm in a few minutes. A long-standing paradigm claims that this primordial cell wall, known as the cell plate, is generated by delivery of newly synthesized material from Golgi apparatus-originated secretory vesicles. Here, we show that, in diverse plant species, cell surface material, including plasma membrane proteins, cell wall components, and exogenously applied endocytic tracers, is rapidly delivered to the forming cell plate. Importantly, this occurs even when de novo protein synthesis is blocked. In addition, cytokinesis-specific syntaxin KNOLLE as well as plasma membrane (PM) resident proteins localize to endosomes that fuse to initiate the cell plate. The rate of endocytosis is strongly enhanced during cell plate formation, and its genetic or pharmacological inhibition leads to cytokinesis defects. Our results reveal that endocytic delivery of cell surface material significantly contributes to cell plate formation during plant cytokinesis. ' author: - first_name: Pankaj full_name: Dhonukshe, Pankaj last_name: Dhonukshe - first_name: František full_name: Baluška, František last_name: Baluška - first_name: Markus full_name: Schlicht, Markus last_name: Schlicht - first_name: Andrej full_name: Hlavacka, Andrej last_name: Hlavacka - first_name: Jozef full_name: Šamaj, Jozef last_name: Šamaj - first_name: Jirí full_name: Jirí Friml id: 4159519E-F248-11E8-B48F-1D18A9856A87 last_name: Friml orcid: 0000-0002-8302-7596 - first_name: Theodorus full_name: Gadella, Theodorus W last_name: Gadella citation: ama: Dhonukshe P, Baluška F, Schlicht M, et al. Endocytosis of cell surface material mediates cell plate formation during plant cytokinesis. Developmental Cell. 2006;10(1):137-150. doi:10.1016/j.devcel.2005.11.015 apa: Dhonukshe, P., Baluška, F., Schlicht, M., Hlavacka, A., Šamaj, J., Friml, J., & Gadella, T. (2006). Endocytosis of cell surface material mediates cell plate formation during plant cytokinesis. Developmental Cell. Cell Press. https://doi.org/10.1016/j.devcel.2005.11.015 chicago: Dhonukshe, Pankaj, František Baluška, Markus Schlicht, Andrej Hlavacka, Jozef Šamaj, Jiří Friml, and Theodorus Gadella. “Endocytosis of Cell Surface Material Mediates Cell Plate Formation during Plant Cytokinesis.” Developmental Cell. Cell Press, 2006. https://doi.org/10.1016/j.devcel.2005.11.015. ieee: P. Dhonukshe et al., “Endocytosis of cell surface material mediates cell plate formation during plant cytokinesis,” Developmental Cell, vol. 10, no. 1. Cell Press, pp. 137–150, 2006. ista: Dhonukshe P, Baluška F, Schlicht M, Hlavacka A, Šamaj J, Friml J, Gadella T. 2006. Endocytosis of cell surface material mediates cell plate formation during plant cytokinesis. Developmental Cell. 10(1), 137–150. mla: Dhonukshe, Pankaj, et al. “Endocytosis of Cell Surface Material Mediates Cell Plate Formation during Plant Cytokinesis.” Developmental Cell, vol. 10, no. 1, Cell Press, 2006, pp. 137–50, doi:10.1016/j.devcel.2005.11.015. short: P. Dhonukshe, F. Baluška, M. Schlicht, A. Hlavacka, J. Šamaj, J. Friml, T. Gadella, Developmental Cell 10 (2006) 137–150. date_created: 2018-12-11T12:00:49Z date_published: 2006-01-01T00:00:00Z date_updated: 2021-01-12T07:40:24Z day: '01' doi: 10.1016/j.devcel.2005.11.015 extern: 1 intvolume: ' 10' issue: '1' month: '01' page: 137 - 150 publication: Developmental Cell publication_status: published publisher: Cell Press publist_id: '3696' quality_controlled: 0 status: public title: Endocytosis of cell surface material mediates cell plate formation during plant cytokinesis type: journal_article volume: 10 year: '2006' ... --- _id: '3011' abstract: - lang: eng text: Polar flow of the phytohormone auxin requires plasma membrane‐associated PIN proteins and underlies multiple developmental processes in plants. Here we address the importance of the polarity of subcellular PIN localization for the directionality of auxin transport in Arabidopsis thaliana. Expression of different PINs in the root epidermis revealed the importance of PIN polar positions for directional auxin flow and root gravitropic growth. Interfering with sequence-embedded polarity signals directly demonstrates that PIN polarity is a primary factor in determining the direction of auxin flow in meristematic tissues. This finding provides a crucial piece in the puzzle of how auxin flow can be redirected via rapid changes in PIN polarity. author: - first_name: Justyna full_name: Wiśniewska, Justyna last_name: Wiśniewska - first_name: Jian full_name: Xu, Jian last_name: Xu - first_name: Daniela full_name: Seifertová, Daniela last_name: Seifertová - first_name: Philip full_name: Brewer, Philip B last_name: Brewer - first_name: Kamil full_name: Růžička, Kamil last_name: Růžička - first_name: Ikram full_name: Blilou, Ikram last_name: Blilou - first_name: David full_name: Rouquié, David last_name: Rouquié - first_name: Eva full_name: Eva Benková id: 38F4F166-F248-11E8-B48F-1D18A9856A87 last_name: Benková orcid: 0000-0002-8510-9739 - first_name: Ben full_name: Scheres, Ben last_name: Scheres - first_name: Jirí full_name: Jirí Friml id: 4159519E-F248-11E8-B48F-1D18A9856A87 last_name: Friml orcid: 0000-0002-8302-7596 citation: ama: Wiśniewska J, Xu J, Seifertová D, et al. Polar PIN localization directs auxin flow in plants. Science. 2006;312(5775). doi:10.1126/science.1121356 apa: Wiśniewska, J., Xu, J., Seifertová, D., Brewer, P., Růžička, K., Blilou, I., … Friml, J. (2006). Polar PIN localization directs auxin flow in plants. Science. American Association for the Advancement of Science. https://doi.org/10.1126/science.1121356 chicago: Wiśniewska, Justyna, Jian Xu, Daniela Seifertová, Philip Brewer, Kamil Růžička, Ikram Blilou, David Rouquié, Eva Benková, Ben Scheres, and Jiří Friml. “Polar PIN Localization Directs Auxin Flow in Plants.” Science. American Association for the Advancement of Science, 2006. https://doi.org/10.1126/science.1121356. ieee: J. Wiśniewska et al., “Polar PIN localization directs auxin flow in plants,” Science, vol. 312, no. 5775. American Association for the Advancement of Science, 2006. ista: Wiśniewska J, Xu J, Seifertová D, Brewer P, Růžička K, Blilou I, Rouquié D, Benková E, Scheres B, Friml J. 2006. Polar PIN localization directs auxin flow in plants. Science. 312(5775). mla: Wiśniewska, Justyna, et al. “Polar PIN Localization Directs Auxin Flow in Plants.” Science, vol. 312, no. 5775, American Association for the Advancement of Science, 2006, doi:10.1126/science.1121356. short: J. Wiśniewska, J. Xu, D. Seifertová, P. Brewer, K. Růžička, I. Blilou, D. Rouquié, E. Benková, B. Scheres, J. Friml, Science 312 (2006). date_created: 2018-12-11T12:00:51Z date_published: 2006-05-12T00:00:00Z date_updated: 2021-01-12T07:40:27Z day: '12' doi: 10.1126/science.1121356 extern: 1 intvolume: ' 312' issue: '5775' month: '05' publication: Science publication_status: published publisher: American Association for the Advancement of Science publist_id: '3691' quality_controlled: 0 status: public title: Polar PIN localization directs auxin flow in plants type: journal_article volume: 312 year: '2006' ... --- _id: '3005' author: - first_name: Jirí full_name: Friml, Jirí id: 4159519E-F248-11E8-B48F-1D18A9856A87 last_name: Friml orcid: 0000-0002-8302-7596 - first_name: Philip full_name: Benfey, Philip last_name: Benfey - first_name: Eva full_name: Benková, Eva id: 38F4F166-F248-11E8-B48F-1D18A9856A87 last_name: Benková orcid: 0000-0002-8510-9739 - first_name: Malcolm full_name: Bennett, Malcolm last_name: Bennett - first_name: Thomas full_name: Berleth, Thomas last_name: Berleth - first_name: Niko full_name: Geldner, Niko last_name: Geldner - first_name: Markus full_name: Grebe, Markus last_name: Grebe - first_name: Marcus full_name: Heisler, Marcus last_name: Heisler - first_name: Jan full_name: Hejátko, Jan last_name: Hejátko - first_name: Gerd full_name: Jürgens, Gerd last_name: Jürgens - first_name: Thomas full_name: Laux, Thomas last_name: Laux - first_name: Keith full_name: Lindsey, Keith last_name: Lindsey - first_name: Wolfgang full_name: Lukowitz, Wolfgang last_name: Lukowitz - first_name: Christian full_name: Luschnig, Christian last_name: Luschnig - first_name: Remko full_name: Offringa, Remko last_name: Offringa - first_name: Ben full_name: Scheres, Ben last_name: Scheres - first_name: Ranjan full_name: Swarup, Ranjan last_name: Swarup - first_name: Ramón full_name: Torres Ruiz, Ramón last_name: Torres Ruiz - first_name: Dolf full_name: Weijers, Dolf last_name: Weijers - first_name: Eva full_name: Zažímalová, Eva last_name: Zažímalová citation: ama: 'Friml J, Benfey P, Benková E, et al. Apical-basal polarity: Why plant cells don’t stand on their heads. Trends in Plant Science. 2006;11(1):12-14. doi:10.1016/j.tplants.2005.11.010' apa: 'Friml, J., Benfey, P., Benková, E., Bennett, M., Berleth, T., Geldner, N., … Zažímalová, E. (2006). Apical-basal polarity: Why plant cells don’t stand on their heads. Trends in Plant Science. Cell Press. https://doi.org/10.1016/j.tplants.2005.11.010' chicago: 'Friml, Jiří, Philip Benfey, Eva Benková, Malcolm Bennett, Thomas Berleth, Niko Geldner, Markus Grebe, et al. “Apical-Basal Polarity: Why Plant Cells Don’t Stand on Their Heads.” Trends in Plant Science. Cell Press, 2006. https://doi.org/10.1016/j.tplants.2005.11.010.' ieee: 'J. Friml et al., “Apical-basal polarity: Why plant cells don’t stand on their heads,” Trends in Plant Science, vol. 11, no. 1. Cell Press, pp. 12–14, 2006.' ista: 'Friml J, Benfey P, Benková E, Bennett M, Berleth T, Geldner N, Grebe M, Heisler M, Hejátko J, Jürgens G, Laux T, Lindsey K, Lukowitz W, Luschnig C, Offringa R, Scheres B, Swarup R, Torres Ruiz R, Weijers D, Zažímalová E. 2006. Apical-basal polarity: Why plant cells don’t stand on their heads. Trends in Plant Science. 11(1), 12–14.' mla: 'Friml, Jiří, et al. “Apical-Basal Polarity: Why Plant Cells Don’t Stand on Their Heads.” Trends in Plant Science, vol. 11, no. 1, Cell Press, 2006, pp. 12–14, doi:10.1016/j.tplants.2005.11.010.' short: J. Friml, P. Benfey, E. Benková, M. Bennett, T. Berleth, N. Geldner, M. Grebe, M. Heisler, J. Hejátko, G. Jürgens, T. Laux, K. Lindsey, W. Lukowitz, C. Luschnig, R. Offringa, B. Scheres, R. Swarup, R. Torres Ruiz, D. Weijers, E. Zažímalová, Trends in Plant Science 11 (2006) 12–14. date_created: 2018-12-11T12:00:49Z date_published: 2006-01-01T00:00:00Z date_updated: 2021-01-12T07:40:24Z day: '01' doi: 10.1016/j.tplants.2005.11.010 extern: '1' intvolume: ' 11' issue: '1' language: - iso: eng month: '01' oa_version: None page: 12 - 14 publication: Trends in Plant Science publication_status: published publisher: Cell Press publist_id: '3697' status: public title: 'Apical-basal polarity: Why plant cells don''t stand on their heads' type: journal_article user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87 volume: 11 year: '2006' ... --- _id: '3008' abstract: - lang: eng text: Plants and some animals have a profound capacity to regenerate organs from adult tissues. Molecular mechanisms for regeneration have, however, been largely unexplored. Here we investigate a local regeneration response in Arabidopsis roots. Laser-induced wounding disrupts the flow of auxin-a cell-fate-instructive plant hormone-in root tips, and we demonstrate that resulting cell-fate changes require the PLETHORA, SHORTROOT, and SCARECROW transcription factors. These transcription factors regulate the expression and polar position of PIN auxin efflux-facilitating membrane proteins to reconstitute auxin transport in renewed root tips. Thus, a regeneration mechanism using embryonic root stem-cell patterning factors first responds to and subsequently stabilizes a new hormone distribution. author: - first_name: Jian full_name: Xu, Jian last_name: Xu - first_name: Hugo full_name: Hofhuis, Hugo last_name: Hofhuis - first_name: Renze full_name: Heidstra, Renze last_name: Heidstra - first_name: Michael full_name: Sauer, Michael last_name: Sauer - first_name: Jirí full_name: Jirí Friml id: 4159519E-F248-11E8-B48F-1D18A9856A87 last_name: Friml orcid: 0000-0002-8302-7596 - first_name: Ben full_name: Scheres, Ben last_name: Scheres citation: ama: Xu J, Hofhuis H, Heidstra R, Sauer M, Friml J, Scheres B. A molecular framework for plant regeneration. Science. 2006;311(5759):385-388. doi:10.1126/science.1121790 apa: Xu, J., Hofhuis, H., Heidstra, R., Sauer, M., Friml, J., & Scheres, B. (2006). A molecular framework for plant regeneration. Science. American Association for the Advancement of Science. https://doi.org/10.1126/science.1121790 chicago: Xu, Jian, Hugo Hofhuis, Renze Heidstra, Michael Sauer, Jiří Friml, and Ben Scheres. “A Molecular Framework for Plant Regeneration.” Science. American Association for the Advancement of Science, 2006. https://doi.org/10.1126/science.1121790. ieee: J. Xu, H. Hofhuis, R. Heidstra, M. Sauer, J. Friml, and B. Scheres, “A molecular framework for plant regeneration,” Science, vol. 311, no. 5759. American Association for the Advancement of Science, pp. 385–388, 2006. ista: Xu J, Hofhuis H, Heidstra R, Sauer M, Friml J, Scheres B. 2006. A molecular framework for plant regeneration. Science. 311(5759), 385–388. mla: Xu, Jian, et al. “A Molecular Framework for Plant Regeneration.” Science, vol. 311, no. 5759, American Association for the Advancement of Science, 2006, pp. 385–88, doi:10.1126/science.1121790. short: J. Xu, H. Hofhuis, R. Heidstra, M. Sauer, J. Friml, B. Scheres, Science 311 (2006) 385–388. date_created: 2018-12-11T12:00:50Z date_published: 2006-01-20T00:00:00Z date_updated: 2021-01-12T07:40:25Z day: '20' doi: 10.1126/science.1121790 extern: 1 intvolume: ' 311' issue: '5759' month: '01' page: 385 - 388 publication: Science publication_status: published publisher: American Association for the Advancement of Science publist_id: '3695' quality_controlled: 0 status: public title: A molecular framework for plant regeneration type: journal_article volume: 311 year: '2006' ... --- _id: '3009' author: - first_name: Tomasz full_name: Paciorek, Tomasz last_name: Paciorek - first_name: Jirí full_name: Friml, Jirí id: 4159519E-F248-11E8-B48F-1D18A9856A87 last_name: Friml orcid: 0000-0002-8302-7596 citation: ama: Paciorek T, Friml J. Auxin signaling. Journal of Cell Science. 2006;119(7):1199-1202. doi:10.1242/jcs.02910 apa: Paciorek, T., & Friml, J. (2006). Auxin signaling. Journal of Cell Science. Company of Biologists. https://doi.org/10.1242/jcs.02910 chicago: Paciorek, Tomasz, and Jiří Friml. “Auxin Signaling.” Journal of Cell Science. Company of Biologists, 2006. https://doi.org/10.1242/jcs.02910. ieee: T. Paciorek and J. Friml, “Auxin signaling,” Journal of Cell Science, vol. 119, no. 7. Company of Biologists, pp. 1199–1202, 2006. ista: Paciorek T, Friml J. 2006. Auxin signaling. Journal of Cell Science. 119(7), 1199–1202. mla: Paciorek, Tomasz, and Jiří Friml. “Auxin Signaling.” Journal of Cell Science, vol. 119, no. 7, Company of Biologists, 2006, pp. 1199–202, doi:10.1242/jcs.02910. short: T. Paciorek, J. Friml, Journal of Cell Science 119 (2006) 1199–1202. date_created: 2018-12-11T12:00:50Z date_published: 2006-01-01T00:00:00Z date_updated: 2021-01-12T07:40:25Z day: '01' doi: 10.1242/jcs.02910 extern: '1' external_id: pmid: - ' 16554435' intvolume: ' 119' issue: '7' language: - iso: eng main_file_link: - open_access: '1' url: https://www.ncbi.nlm.nih.gov/pubmed/16554435 month: '01' oa: 1 oa_version: Published Version page: 1199 - 1202 pmid: 1 publication: Journal of Cell Science publication_status: published publisher: Company of Biologists publist_id: '3693' quality_controlled: '1' status: public title: Auxin signaling type: journal_article user_id: 3E5EF7F0-F248-11E8-B48F-1D18A9856A87 volume: 119 year: '2006' ... --- _id: '3016' abstract: - lang: eng text: Plant development is characterized by a profound ability to regenerate and form tissues with new axes of polarity. An unsolved question concerns how the position within a tissue and cues from neighboring cells are integrated to specify the polarity of individual cells. The canalization hypothesis proposes a feedback effect of the phytohormone auxin on the directionality of intercellular auxin flow as a means to polarize tissues. Here we identify a cellular and molecular mechanism for canalization. Local auxin application, wounding, or auxin accumulation during de novo organ formation lead to rearrangements in the subcellular polar localization of PIN auxin transport components. This auxin effect on PIN polarity is cell-specific, does not depend on PIN transcription, and involves the Aux/IAA-ARF (indole-3-acetic acid-auxin response factor) signaling pathway. Our data suggest that auxin acts as polarizing cue, which links individual cell polarity with tissue and organ polarity through control of PIN polar targeting. This feedback regulation provides a conceptual framework for polarization during multiple regenerative and patterning processes in plants. article_processing_charge: No author: - first_name: Michael full_name: Sauer, Michael last_name: Sauer - first_name: Jozef full_name: Balla, Jozef last_name: Balla - first_name: Christian full_name: Luschnig, Christian last_name: Luschnig - first_name: Justyna full_name: Wiśniewska, Justyna last_name: Wiśniewska - first_name: Vilém full_name: Reinöhl, Vilém last_name: Reinöhl - first_name: Jirí full_name: Friml, Jirí id: 4159519E-F248-11E8-B48F-1D18A9856A87 last_name: Friml orcid: 0000-0002-8302-7596 - first_name: Eva full_name: Benková, Eva id: 38F4F166-F248-11E8-B48F-1D18A9856A87 last_name: Benková orcid: 0000-0002-8510-9739 citation: ama: Sauer M, Balla J, Luschnig C, et al. Canalization of auxin flow by Aux/IAA-ARF-dependent feedback regulation of PIN polarity. Genes and Development. 2006;20(20):2902-2911. doi:10.1101/gad.390806 apa: Sauer, M., Balla, J., Luschnig, C., Wiśniewska, J., Reinöhl, V., Friml, J., & Benková, E. (2006). Canalization of auxin flow by Aux/IAA-ARF-dependent feedback regulation of PIN polarity. Genes and Development. Cold Spring Harbor Laboratory Press. https://doi.org/10.1101/gad.390806 chicago: Sauer, Michael, Jozef Balla, Christian Luschnig, Justyna Wiśniewska, Vilém Reinöhl, Jiří Friml, and Eva Benková. “Canalization of Auxin Flow by Aux/IAA-ARF-Dependent Feedback Regulation of PIN Polarity.” Genes and Development. Cold Spring Harbor Laboratory Press, 2006. https://doi.org/10.1101/gad.390806. ieee: M. Sauer et al., “Canalization of auxin flow by Aux/IAA-ARF-dependent feedback regulation of PIN polarity,” Genes and Development, vol. 20, no. 20. Cold Spring Harbor Laboratory Press, pp. 2902–2911, 2006. ista: Sauer M, Balla J, Luschnig C, Wiśniewska J, Reinöhl V, Friml J, Benková E. 2006. Canalization of auxin flow by Aux/IAA-ARF-dependent feedback regulation of PIN polarity. Genes and Development. 20(20), 2902–2911. mla: Sauer, Michael, et al. “Canalization of Auxin Flow by Aux/IAA-ARF-Dependent Feedback Regulation of PIN Polarity.” Genes and Development, vol. 20, no. 20, Cold Spring Harbor Laboratory Press, 2006, pp. 2902–11, doi:10.1101/gad.390806. short: M. Sauer, J. Balla, C. Luschnig, J. Wiśniewska, V. Reinöhl, J. Friml, E. Benková, Genes and Development 20 (2006) 2902–2911. date_created: 2018-12-11T12:00:53Z date_published: 2006-10-15T00:00:00Z date_updated: 2021-11-16T07:53:09Z day: '15' doi: 10.1101/gad.390806 extern: '1' intvolume: ' 20' issue: '20' language: - iso: eng month: '10' oa_version: None page: 2902 - 2911 publication: Genes and Development publication_status: published publisher: Cold Spring Harbor Laboratory Press publist_id: '3686' related_material: link: - relation: erratum url: http://genesdev.cshlp.org/content/21/11/1431.short status: public title: Canalization of auxin flow by Aux/IAA-ARF-dependent feedback regulation of PIN polarity type: journal_article user_id: 8b945eb4-e2f2-11eb-945a-df72226e66a9 volume: 20 year: '2006' ... --- _id: '3017' abstract: - lang: eng text: The plant hormone auxin plays crucial roles in regulating plant growth development, including embryo and root patterning, organ formation, vascular tissue differentiation and growth responses to environmental stimuli. Asymmetric auxin distribution patterns have been observed within tissues, and these so-called auxin gradients change dynamically during different developmental processes. Most auxin is synthesized in the shoot and distributed directionally throughout the plant. This polar auxin transport is mediated by auxin influx and efflux facilitators, whose subcellular polar localizations guide the direction of auxin flow. The polar localization of PIN auxin efflux carriers changes in response to developmental and external cues in order to channel auxin flow in a regulated manner for organized growth. Auxin itself modulates the expression and subcellular localization of PIN proteins, contributing to a complex pattern of feedback regulation. Here we review the available information mainly from studies of a model plant, Arabidopsis thaliana, on the generation of auxin gradients, the regulation of polar auxin transport and further downstream cellular events. author: - first_name: Hirokazu full_name: Tanaka, Hirokazu last_name: Tanaka - first_name: Pankaj full_name: Dhonukshe, Pankaj last_name: Dhonukshe - first_name: Philip full_name: Brewer, Philip last_name: Brewer - first_name: Jirí full_name: Friml, Jirí id: 4159519E-F248-11E8-B48F-1D18A9856A87 last_name: Friml orcid: 0000-0002-8302-7596 citation: ama: 'Tanaka H, Dhonukshe P, Brewer P, Friml J. Spatiotemporal asymmetric auxin distribution: A means to coordinate plant development. Cellular and Molecular Life Sciences. 2006;63(23):2738-2754. doi:10.1007/s00018-006-6116-5' apa: 'Tanaka, H., Dhonukshe, P., Brewer, P., & Friml, J. (2006). Spatiotemporal asymmetric auxin distribution: A means to coordinate plant development. Cellular and Molecular Life Sciences. Birkhäuser. https://doi.org/10.1007/s00018-006-6116-5' chicago: 'Tanaka, Hirokazu, Pankaj Dhonukshe, Philip Brewer, and Jiří Friml. “Spatiotemporal Asymmetric Auxin Distribution: A Means to Coordinate Plant Development.” Cellular and Molecular Life Sciences. Birkhäuser, 2006. https://doi.org/10.1007/s00018-006-6116-5.' ieee: 'H. Tanaka, P. Dhonukshe, P. Brewer, and J. Friml, “Spatiotemporal asymmetric auxin distribution: A means to coordinate plant development,” Cellular and Molecular Life Sciences, vol. 63, no. 23. Birkhäuser, pp. 2738–2754, 2006.' ista: 'Tanaka H, Dhonukshe P, Brewer P, Friml J. 2006. Spatiotemporal asymmetric auxin distribution: A means to coordinate plant development. Cellular and Molecular Life Sciences. 63(23), 2738–2754.' mla: 'Tanaka, Hirokazu, et al. “Spatiotemporal Asymmetric Auxin Distribution: A Means to Coordinate Plant Development.” Cellular and Molecular Life Sciences, vol. 63, no. 23, Birkhäuser, 2006, pp. 2738–54, doi:10.1007/s00018-006-6116-5.' short: H. Tanaka, P. Dhonukshe, P. Brewer, J. Friml, Cellular and Molecular Life Sciences 63 (2006) 2738–2754. date_created: 2018-12-11T12:00:53Z date_published: 2006-12-01T00:00:00Z date_updated: 2021-01-12T07:40:29Z day: '01' doi: 10.1007/s00018-006-6116-5 extern: '1' intvolume: ' 63' issue: '23' language: - iso: eng month: '12' oa_version: None page: 2738 - 2754 publication: Cellular and Molecular Life Sciences publication_status: published publisher: Birkhäuser publist_id: '3685' quality_controlled: '1' status: public title: 'Spatiotemporal asymmetric auxin distribution: A means to coordinate plant development' type: journal_article user_id: 3E5EF7F0-F248-11E8-B48F-1D18A9856A87 volume: 63 year: '2006' ... --- _id: '3018' abstract: - lang: eng text: The directional flow of the plant hormone auxin mediates multiple developmental processes, including patterning and tropisms. Apical and basal plasma membrane localization of AUXIN-RESISTANT1 (AUX1) and PIN-FORMED1 (PIN1) auxin transport components underpins the directionality of intercellular auxin flow in Arabidopsis thaliana roots. Here, we examined the mechanism of polar trafficking of AUX1. Real-time live cell analysis along with subcellular markers revealed that AUX1 resides at the apical plasma membrane of protophloem cells and at highly dynamic subpopulations of Golgi apparatus and endosomes in all cell types. Plasma membrane and intracellular pools of AUX1 are interconnected by actin-dependent constitutive trafficking, which is not sensitive to the vesicle trafficking inhibitor brefeldin A. AUX1 subcellular dynamics are not influenced by the auxin influx inhibitor NOA but are blocked by the auxin efflux inhibitors TIBA and PBA. Furthermore, auxin transport inhibitors and interference with the sterol composition of membranes disrupt polar AUX1 distribution at the plasma membrane. Compared with PIN1 trafficking, AUX1 dynamics display different sensitivities to trafficking inhibitors and are independent of the endosomal trafficking regulator ARF GEF GNOM. Hence, AUX1 uses a novel trafficking pathway in plants that is distinct from PIN trafficking, providing an additional mechanism for the fine regulation of auxin transport. author: - first_name: Jürgen full_name: Kleine-Vehn, Jürgen last_name: Kleine Vehn - first_name: Pankaj full_name: Dhonukshe, Pankaj last_name: Dhonukshe - first_name: Ranjan full_name: Swarup, Ranjan last_name: Swarup - first_name: Malcolm full_name: Bennett, Malcolm last_name: Bennett - first_name: Jirí full_name: Jirí Friml id: 4159519E-F248-11E8-B48F-1D18A9856A87 last_name: Friml orcid: 0000-0002-8302-7596 citation: ama: Kleine Vehn J, Dhonukshe P, Swarup R, Bennett M, Friml J. Subcellular trafficking of the Arabidopsis auxin influx carrier AUX1 uses a novel pathway distinct from PIN1. Plant Cell. 2006;18(11):3171-3181. doi:10.1105/tpc.106.042770 apa: Kleine Vehn, J., Dhonukshe, P., Swarup, R., Bennett, M., & Friml, J. (2006). Subcellular trafficking of the Arabidopsis auxin influx carrier AUX1 uses a novel pathway distinct from PIN1. Plant Cell. American Society of Plant Biologists. https://doi.org/10.1105/tpc.106.042770 chicago: Kleine Vehn, Jürgen, Pankaj Dhonukshe, Ranjan Swarup, Malcolm Bennett, and Jiří Friml. “Subcellular Trafficking of the Arabidopsis Auxin Influx Carrier AUX1 Uses a Novel Pathway Distinct from PIN1.” Plant Cell. American Society of Plant Biologists, 2006. https://doi.org/10.1105/tpc.106.042770. ieee: J. Kleine Vehn, P. Dhonukshe, R. Swarup, M. Bennett, and J. Friml, “Subcellular trafficking of the Arabidopsis auxin influx carrier AUX1 uses a novel pathway distinct from PIN1,” Plant Cell, vol. 18, no. 11. American Society of Plant Biologists, pp. 3171–3181, 2006. ista: Kleine Vehn J, Dhonukshe P, Swarup R, Bennett M, Friml J. 2006. Subcellular trafficking of the Arabidopsis auxin influx carrier AUX1 uses a novel pathway distinct from PIN1. Plant Cell. 18(11), 3171–3181. mla: Kleine Vehn, Jürgen, et al. “Subcellular Trafficking of the Arabidopsis Auxin Influx Carrier AUX1 Uses a Novel Pathway Distinct from PIN1.” Plant Cell, vol. 18, no. 11, American Society of Plant Biologists, 2006, pp. 3171–81, doi:10.1105/tpc.106.042770. short: J. Kleine Vehn, P. Dhonukshe, R. Swarup, M. Bennett, J. Friml, Plant Cell 18 (2006) 3171–3181. date_created: 2018-12-11T12:00:53Z date_published: 2006-11-01T00:00:00Z date_updated: 2021-01-12T07:40:29Z day: '01' doi: 10.1105/tpc.106.042770 extern: 1 intvolume: ' 18' issue: '11' month: '11' page: 3171 - 3181 publication: Plant Cell publication_status: published publisher: American Society of Plant Biologists publist_id: '3684' quality_controlled: 0 status: public title: Subcellular trafficking of the Arabidopsis auxin influx carrier AUX1 uses a novel pathway distinct from PIN1 type: journal_article volume: 18 year: '2006' ... --- _id: '3020' abstract: - lang: eng text: High throughput microarray transcription analyses provide us with the expression profiles for large amounts of plant genes. However, their tissue and cellular resolution is limited. Thus, for detailed functional analysis, it is still necessary to examine the expression pattern of selected candidate genes at a cellular level. Here, we present an in situ mRNA hybridization method that is routinely used for the analysis of plant gene expression patterns. The protocol is optimized for whole mount mRNA localizations in Arabidopsis seedling tissues including embryos, roots, hypocotyls and young primary leaves. It can also be used for comparable tissues in other species. Part of the protocol can also be automated and performed by a liquid handling robot. Here we present a detailed protocol, recommended controls and troubleshooting, along with examples of several applications. The total time to carry out the entire procedure is ∼7 d, depending on the tissue used. author: - first_name: Jan full_name: Hejátko, Jan last_name: Hejátko - first_name: Ikram full_name: Blilou, Ikram last_name: Blilou - first_name: Philip full_name: Brewer, Philip B last_name: Brewer - first_name: Jirí full_name: Jirí Friml id: 4159519E-F248-11E8-B48F-1D18A9856A87 last_name: Friml orcid: 0000-0002-8302-7596 - first_name: Ben full_name: Scheres, Ben last_name: Scheres - first_name: Eva full_name: Eva Benková id: 38F4F166-F248-11E8-B48F-1D18A9856A87 last_name: Benková orcid: 0000-0002-8510-9739 citation: ama: Hejátko J, Blilou I, Brewer P, Friml J, Scheres B, Benková E. In situ hybridization technique for mRNA detection in whole mount Arabidopsis samples. Nature Protocols. 2006;1(4):1939-1946. doi:10.1038/nprot.2006.333 apa: Hejátko, J., Blilou, I., Brewer, P., Friml, J., Scheres, B., & Benková, E. (2006). In situ hybridization technique for mRNA detection in whole mount Arabidopsis samples. Nature Protocols. Nature Publishing Group. https://doi.org/10.1038/nprot.2006.333 chicago: Hejátko, Jan, Ikram Blilou, Philip Brewer, Jiří Friml, Ben Scheres, and Eva Benková. “In Situ Hybridization Technique for MRNA Detection in Whole Mount Arabidopsis Samples.” Nature Protocols. Nature Publishing Group, 2006. https://doi.org/10.1038/nprot.2006.333. ieee: J. Hejátko, I. Blilou, P. Brewer, J. Friml, B. Scheres, and E. Benková, “In situ hybridization technique for mRNA detection in whole mount Arabidopsis samples,” Nature Protocols, vol. 1, no. 4. Nature Publishing Group, pp. 1939–1946, 2006. ista: Hejátko J, Blilou I, Brewer P, Friml J, Scheres B, Benková E. 2006. In situ hybridization technique for mRNA detection in whole mount Arabidopsis samples. Nature Protocols. 1(4), 1939–1946. mla: Hejátko, Jan, et al. “In Situ Hybridization Technique for MRNA Detection in Whole Mount Arabidopsis Samples.” Nature Protocols, vol. 1, no. 4, Nature Publishing Group, 2006, pp. 1939–46, doi:10.1038/nprot.2006.333. short: J. Hejátko, I. Blilou, P. Brewer, J. Friml, B. Scheres, E. Benková, Nature Protocols 1 (2006) 1939–1946. date_created: 2018-12-11T12:00:54Z date_published: 2006-11-01T00:00:00Z date_updated: 2021-01-12T07:40:30Z day: '01' doi: 10.1038/nprot.2006.333 extern: 1 intvolume: ' 1' issue: '4' month: '11' page: 1939 - 1946 publication: Nature Protocols publication_status: published publisher: Nature Publishing Group publist_id: '3683' quality_controlled: 0 status: public title: In situ hybridization technique for mRNA detection in whole mount Arabidopsis samples type: journal_article volume: 1 year: '2006' ... --- _id: '3015' abstract: - lang: eng text: 'As the field of plant molecular biology is swiftly advancing, a need has been created for methods that allow rapid and reliable in situ localization of proteins in plant cells. Here we describe a whole-mount ''immunolocalization'' technique for various plant tissues, including roots, hypocotyls, cotyledons, young primary leaves and embryos of Arabidopsis thaliana and other species. The detailed protocol, recommended controls and troubleshooting are presented, along with examples of applications. The protocol consists of five main procedures: tissue fixation, tissue permeation, blocking, primary and secondary antibody incubation. Notably, the first procedure (tissue fixation) includes several steps (4-12) that are absolutely necessary for protein localization in hypocotyls, cotyledons and young primary leaves but should be omitted for other tissues. The protocol is usually done in 3 days, but could also be completed in 2 days.' author: - first_name: Michael full_name: Sauer, Michael last_name: Sauer - first_name: Tomasz full_name: Paciorek, Tomasz last_name: Paciorek - first_name: Eva full_name: Eva Benková id: 38F4F166-F248-11E8-B48F-1D18A9856A87 last_name: Benková orcid: 0000-0002-8510-9739 - first_name: Jirí full_name: Jirí Friml id: 4159519E-F248-11E8-B48F-1D18A9856A87 last_name: Friml orcid: 0000-0002-8302-7596 citation: ama: Sauer M, Paciorek T, Benková E, Friml J. Immunocytochemical techniques for whole mount in situ protein localization in plants. Nature Protocols. 2006;1(1):98-103. doi:10.1038/nprot.2006.15 apa: Sauer, M., Paciorek, T., Benková, E., & Friml, J. (2006). Immunocytochemical techniques for whole mount in situ protein localization in plants. Nature Protocols. Nature Publishing Group. https://doi.org/10.1038/nprot.2006.15 chicago: Sauer, Michael, Tomasz Paciorek, Eva Benková, and Jiří Friml. “Immunocytochemical Techniques for Whole Mount in Situ Protein Localization in Plants.” Nature Protocols. Nature Publishing Group, 2006. https://doi.org/10.1038/nprot.2006.15. ieee: M. Sauer, T. Paciorek, E. Benková, and J. Friml, “Immunocytochemical techniques for whole mount in situ protein localization in plants,” Nature Protocols, vol. 1, no. 1. Nature Publishing Group, pp. 98–103, 2006. ista: Sauer M, Paciorek T, Benková E, Friml J. 2006. Immunocytochemical techniques for whole mount in situ protein localization in plants. Nature Protocols. 1(1), 98–103. mla: Sauer, Michael, et al. “Immunocytochemical Techniques for Whole Mount in Situ Protein Localization in Plants.” Nature Protocols, vol. 1, no. 1, Nature Publishing Group, 2006, pp. 98–103, doi:10.1038/nprot.2006.15. short: M. Sauer, T. Paciorek, E. Benková, J. Friml, Nature Protocols 1 (2006) 98–103. date_created: 2018-12-11T12:00:52Z date_published: 2006-06-01T00:00:00Z date_updated: 2021-01-12T07:40:28Z day: '01' doi: 10.1038/nprot.2006.15 extern: 1 intvolume: ' 1' issue: '1' month: '06' page: 98 - 103 publication: Nature Protocols publication_status: published publisher: Nature Publishing Group publist_id: '3688' quality_controlled: 0 status: public title: Immunocytochemical techniques for whole mount in situ protein localization in plants type: journal_article volume: 1 year: '2006' ... --- _id: '3013' abstract: - lang: eng text: 'There is a growing demand for methods that allow rapid and reliable in situ localization of proteins in plant cells. The immunocytochemistry protocol presented here can be used routinely to observe protein localization patterns in tissue sections of various plant species. This protocol is especially suitable for plant species with more-complex tissue architecture (such as maize, Zea mays), which makes it difficult to use an easier whole-mount procedure for protein localization. To facilitate the antibody-antigen reaction, it is necessary to include a wax-embedding and tissue-sectioning step. The protocol consists of the following procedures: chemical fixation of tissue, dehydration, wax embedding, sectioning, dewaxing, rehydration, blocking and antibody incubation. The detailed protocol, recommended controls and troubleshooting are presented here, along with examples of applications.' author: - first_name: Tomasz full_name: Paciorek, Tomasz last_name: Paciorek - first_name: Michael full_name: Sauer, Michael last_name: Sauer - first_name: Jozef full_name: Balla, Jozef last_name: Balla - first_name: Justyna full_name: Wiśniewska, Justyna last_name: Wiśniewska - first_name: Jirí full_name: Jirí Friml id: 4159519E-F248-11E8-B48F-1D18A9856A87 last_name: Friml orcid: 0000-0002-8302-7596 citation: ama: Paciorek T, Sauer M, Balla J, Wiśniewska J, Friml J. Immunocytochemical technique for protein localization in sections of plant tissues. Nature Protocols. 2006;1(1):104-107. doi:10.1038/nprot.2006.16 apa: Paciorek, T., Sauer, M., Balla, J., Wiśniewska, J., & Friml, J. (2006). Immunocytochemical technique for protein localization in sections of plant tissues. Nature Protocols. Nature Publishing Group. https://doi.org/10.1038/nprot.2006.16 chicago: Paciorek, Tomasz, Michael Sauer, Jozef Balla, Justyna Wiśniewska, and Jiří Friml. “Immunocytochemical Technique for Protein Localization in Sections of Plant Tissues.” Nature Protocols. Nature Publishing Group, 2006. https://doi.org/10.1038/nprot.2006.16. ieee: T. Paciorek, M. Sauer, J. Balla, J. Wiśniewska, and J. Friml, “Immunocytochemical technique for protein localization in sections of plant tissues,” Nature Protocols, vol. 1, no. 1. Nature Publishing Group, pp. 104–107, 2006. ista: Paciorek T, Sauer M, Balla J, Wiśniewska J, Friml J. 2006. Immunocytochemical technique for protein localization in sections of plant tissues. Nature Protocols. 1(1), 104–107. mla: Paciorek, Tomasz, et al. “Immunocytochemical Technique for Protein Localization in Sections of Plant Tissues.” Nature Protocols, vol. 1, no. 1, Nature Publishing Group, 2006, pp. 104–07, doi:10.1038/nprot.2006.16. short: T. Paciorek, M. Sauer, J. Balla, J. Wiśniewska, J. Friml, Nature Protocols 1 (2006) 104–107. date_created: 2018-12-11T12:00:52Z date_published: 2006-06-01T00:00:00Z date_updated: 2021-01-12T07:40:27Z day: '01' doi: 10.1038/nprot.2006.16 extern: 1 intvolume: ' 1' issue: '1' month: '06' page: 104 - 107 publication: Nature Protocols publication_status: published publisher: Nature Publishing Group publist_id: '3689' quality_controlled: 0 status: public title: Immunocytochemical technique for protein localization in sections of plant tissues type: journal_article volume: 1 year: '2006' ... --- _id: '3014' abstract: - lang: eng text: Plant biology is currently confronted with an overflow of expression profile data provided by high-throughput microarray transcription analyses. However, the tissue and cellular resolution of these techniques is limited. Thus, it is still necessary to examine the expression pattern of selected candidate genes at a cellular level. Here we present an in situ mRNA hybridization method that is routinely used in the analysis of gene expression patterns. The protocol is optimized for mRNA localizations in sectioned tissue of Arabidopsis seedlings including embryos, roots, hypocotyls, young primary leaves and flowers. The detailed protocol, recommended controls and troubleshooting are presented along with examples of application. The total time for the process is 10 days. author: - first_name: Philip full_name: Brewer, Philip B last_name: Brewer - first_name: Marcus full_name: Heisler, Marcus G last_name: Heisler - first_name: Jan full_name: Hejátko, Jan last_name: Hejátko - first_name: Jirí full_name: Jirí Friml id: 4159519E-F248-11E8-B48F-1D18A9856A87 last_name: Friml orcid: 0000-0002-8302-7596 - first_name: Eva full_name: Eva Benková id: 38F4F166-F248-11E8-B48F-1D18A9856A87 last_name: Benková orcid: 0000-0002-8510-9739 citation: ama: Brewer P, Heisler M, Hejátko J, Friml J, Benková E. In situ hybridization for mRNA detection in Arabidopsis tissue sections. Nature Protocols. 2006;1(3):1462-1467. doi:10.1038/nprot.2006.226 apa: Brewer, P., Heisler, M., Hejátko, J., Friml, J., & Benková, E. (2006). In situ hybridization for mRNA detection in Arabidopsis tissue sections. Nature Protocols. Nature Publishing Group. https://doi.org/10.1038/nprot.2006.226 chicago: Brewer, Philip, Marcus Heisler, Jan Hejátko, Jiří Friml, and Eva Benková. “In Situ Hybridization for MRNA Detection in Arabidopsis Tissue Sections.” Nature Protocols. Nature Publishing Group, 2006. https://doi.org/10.1038/nprot.2006.226. ieee: P. Brewer, M. Heisler, J. Hejátko, J. Friml, and E. Benková, “In situ hybridization for mRNA detection in Arabidopsis tissue sections,” Nature Protocols, vol. 1, no. 3. Nature Publishing Group, pp. 1462–1467, 2006. ista: Brewer P, Heisler M, Hejátko J, Friml J, Benková E. 2006. In situ hybridization for mRNA detection in Arabidopsis tissue sections. Nature Protocols. 1(3), 1462–1467. mla: Brewer, Philip, et al. “In Situ Hybridization for MRNA Detection in Arabidopsis Tissue Sections.” Nature Protocols, vol. 1, no. 3, Nature Publishing Group, 2006, pp. 1462–67, doi:10.1038/nprot.2006.226. short: P. Brewer, M. Heisler, J. Hejátko, J. Friml, E. Benková, Nature Protocols 1 (2006) 1462–1467. date_created: 2018-12-11T12:00:52Z date_published: 2006-08-01T00:00:00Z date_updated: 2021-01-12T07:40:28Z day: '01' doi: 10.1038/nprot.2006.226 extern: 1 intvolume: ' 1' issue: '3' month: '08' page: 1462 - 1467 publication: Nature Protocols publication_status: published publisher: Nature Publishing Group publist_id: '3687' quality_controlled: 0 status: public title: In situ hybridization for mRNA detection in Arabidopsis tissue sections type: journal_article volume: 1 year: '2006' ... --- _id: '3152' abstract: - lang: eng text: The basic concepts of the molecular machinery that mediates cell migration have been gleaned from cell culture systems. However, the three-dimensional environment within an organism presents migrating cells with a much greater challenge. They must move between and among other cells while interpreting multiple attractive and repulsive cues to choose their proper path. They must coordinate their cell adhesion with their surroundings and know when to start and stop moving. New insights into the control of these remaining mysteries have emerged from genetic dissection and live imaging of germ cell migration in Drosophila, zebrafish, and mouse embryos. In this review, we first describe germ cell migration in cellular and mechanistic detail in these different model systems. We then compare these systems to highlight the emerging principles. Finally, we contrast the migration of germ cells with that of immune and cancer cells to outline the conserved and different mechanisms. author: - first_name: Prabhat full_name: Kunwar, Prabhat S last_name: Kunwar - first_name: Daria E full_name: Daria Siekhaus id: 3D224B9E-F248-11E8-B48F-1D18A9856A87 last_name: Siekhaus orcid: 0000-0001-8323-8353 - first_name: Ruth full_name: Lehmann, Ruth last_name: Lehmann citation: ama: Kunwar P, Siekhaus DE, Lehmann R. In vivo migration A germ cell perspective. Annual Review of Cell and Developmental Biology. 2006;22:237-265. doi:10.1146/annurev.cellbio.22.010305.103337 apa: Kunwar, P., Siekhaus, D. E., & Lehmann, R. (2006). In vivo migration A germ cell perspective. Annual Review of Cell and Developmental Biology. Annual Reviews. https://doi.org/10.1146/annurev.cellbio.22.010305.103337 chicago: Kunwar, Prabhat, Daria E Siekhaus, and Ruth Lehmann. “In Vivo Migration A Germ Cell Perspective.” Annual Review of Cell and Developmental Biology. Annual Reviews, 2006. https://doi.org/10.1146/annurev.cellbio.22.010305.103337. ieee: P. Kunwar, D. E. Siekhaus, and R. Lehmann, “In vivo migration A germ cell perspective,” Annual Review of Cell and Developmental Biology, vol. 22. Annual Reviews, pp. 237–265, 2006. ista: Kunwar P, Siekhaus DE, Lehmann R. 2006. In vivo migration A germ cell perspective. Annual Review of Cell and Developmental Biology. 22, 237–265. mla: Kunwar, Prabhat, et al. “In Vivo Migration A Germ Cell Perspective.” Annual Review of Cell and Developmental Biology, vol. 22, Annual Reviews, 2006, pp. 237–65, doi:10.1146/annurev.cellbio.22.010305.103337. short: P. Kunwar, D.E. Siekhaus, R. Lehmann, Annual Review of Cell and Developmental Biology 22 (2006) 237–265. date_created: 2018-12-11T12:01:42Z date_published: 2006-06-14T00:00:00Z date_updated: 2021-01-12T07:41:25Z day: '14' doi: 10.1146/annurev.cellbio.22.010305.103337 extern: 1 intvolume: ' 22' month: '06' page: 237 - 265 publication: Annual Review of Cell and Developmental Biology publication_status: published publisher: Annual Reviews publist_id: '3543' quality_controlled: 0 status: public title: In vivo migration A germ cell perspective type: journal_article volume: 22 year: '2006' ... --- _id: '3189' abstract: - lang: eng text: This paper presents an algorithm capable of real-time separation of foreground from background in monocular video sequences. Automatic segmentation of layers from colour/contrast or from motion alone is known to be error-prone. Here motion, colour and contrast cues are probabilistically fused together with spatial and temporal priors to infer layers accurately and efficiently. Central to our algorithm is the fact that pixel velocities are not needed, thus removing the need for optical flow estimation, with its tendency to error and computational expense. Instead, an efficient motion vs non-motion classifier is trained to operate directly and jointly on intensity-change and contrast. Its output is then fused with colour information. The prior on segmentation is represented by a second order, temporal, Hidden Markov Model, together with a spatial MRF favouring coherence except where contrast is high. Finally, accurate layer segmentation and explicit occlusion detection are efficiently achieved by binary graph cut. The segmentation accuracy of the proposed algorithm is quantitatively evaluated with respect to existing ground-truth data and found to be comparable to the accuracy of a state of the art stereo segmentation algorithm. Fore-ground/background segmentation is demonstrated in the application of live background substitution and shown to generate convincingly good quality composite video. author: - first_name: Antonio full_name: Criminisi, Antonio last_name: Criminisi - first_name: Geoffrey full_name: Cross, Geoffrey last_name: Cross - first_name: Andrew full_name: Blake, Andrew last_name: Blake - first_name: Vladimir full_name: Vladimir Kolmogorov id: 3D50B0BA-F248-11E8-B48F-1D18A9856A87 last_name: Kolmogorov citation: ama: 'Criminisi A, Cross G, Blake A, Kolmogorov V. Bilayer segmentation of live video. In: Vol 1. IEEE; 2006:53-60. doi:10.1109/CVPR.2006.69' apa: 'Criminisi, A., Cross, G., Blake, A., & Kolmogorov, V. (2006). Bilayer segmentation of live video (Vol. 1, pp. 53–60). Presented at the CVPR: Computer Vision and Pattern Recognition, IEEE. https://doi.org/10.1109/CVPR.2006.69' chicago: Criminisi, Antonio, Geoffrey Cross, Andrew Blake, and Vladimir Kolmogorov. “Bilayer Segmentation of Live Video,” 1:53–60. IEEE, 2006. https://doi.org/10.1109/CVPR.2006.69. ieee: 'A. Criminisi, G. Cross, A. Blake, and V. Kolmogorov, “Bilayer segmentation of live video,” presented at the CVPR: Computer Vision and Pattern Recognition, 2006, vol. 1, pp. 53–60.' ista: 'Criminisi A, Cross G, Blake A, Kolmogorov V. 2006. Bilayer segmentation of live video. CVPR: Computer Vision and Pattern Recognition vol. 1, 53–60.' mla: Criminisi, Antonio, et al. Bilayer Segmentation of Live Video. Vol. 1, IEEE, 2006, pp. 53–60, doi:10.1109/CVPR.2006.69. short: A. Criminisi, G. Cross, A. Blake, V. Kolmogorov, in:, IEEE, 2006, pp. 53–60. conference: name: 'CVPR: Computer Vision and Pattern Recognition' date_created: 2018-12-11T12:01:54Z date_published: 2006-07-05T00:00:00Z date_updated: 2021-01-12T07:41:40Z day: '05' doi: 10.1109/CVPR.2006.69 extern: 1 intvolume: ' 1' main_file_link: - open_access: '0' url: http://research.microsoft.com/en-us/um/people/ablake/papers/ablake/criminisi_cvpr06.pdf month: '07' page: 53 - 60 publication_status: published publisher: IEEE publist_id: '3494' quality_controlled: 0 status: public title: Bilayer segmentation of live video type: conference volume: 1 year: '2006' ... --- _id: '3190' abstract: - lang: eng text: Algorithms for discrete energy minimization are of fundamental importance in computer vision. In this paper, we focus on the recent technique proposed by Wainwright et al. (Nov. 2005)- tree-reweighted max-product message passing (TRW). It was inspired by the problem of maximizing a lower bound on the energy. However, the algorithm is not guaranteed to increase this bound - it may actually go down. In addition, TRW does not always converge. We develop a modification of this algorithm which we call sequential tree-reweighted message passing. Its main property is that the bound is guaranteed not to decrease. We also give a weak tree agreement condition which characterizes local maxima of the bound with respect to TRW algorithms. We prove that our algorithm has a limit point that achieves weak tree agreement. Finally, we show that, our algorithm requires half as much memory as traditional message passing approaches. Experimental results demonstrate that on certain synthetic and real problems, our algorithm outperforms both the ordinary belief propagation and tree-reweighted algorithm in (M. J. Wainwright, et al., Nov. 2005). In addition, on stereo problems with Potts interactions, we obtain a lower energy than graph cuts. author: - first_name: Vladimir full_name: Vladimir Kolmogorov id: 3D50B0BA-F248-11E8-B48F-1D18A9856A87 last_name: Kolmogorov citation: ama: Kolmogorov V. Convergent tree reweighted message passing for energy minimization. IEEE Transactions on Pattern Analysis and Machine Intelligence. 2006;28(10):1568-1583. doi:10.1109/TPAMI.2006.200 apa: Kolmogorov, V. (2006). Convergent tree reweighted message passing for energy minimization. IEEE Transactions on Pattern Analysis and Machine Intelligence. IEEE. https://doi.org/10.1109/TPAMI.2006.200 chicago: Kolmogorov, Vladimir. “Convergent Tree Reweighted Message Passing for Energy Minimization.” IEEE Transactions on Pattern Analysis and Machine Intelligence. IEEE, 2006. https://doi.org/10.1109/TPAMI.2006.200. ieee: V. Kolmogorov, “Convergent tree reweighted message passing for energy minimization,” IEEE Transactions on Pattern Analysis and Machine Intelligence, vol. 28, no. 10. IEEE, pp. 1568–1583, 2006. ista: Kolmogorov V. 2006. Convergent tree reweighted message passing for energy minimization. IEEE Transactions on Pattern Analysis and Machine Intelligence. 28(10), 1568–1583. mla: Kolmogorov, Vladimir. “Convergent Tree Reweighted Message Passing for Energy Minimization.” IEEE Transactions on Pattern Analysis and Machine Intelligence, vol. 28, no. 10, IEEE, 2006, pp. 1568–83, doi:10.1109/TPAMI.2006.200. short: V. Kolmogorov, IEEE Transactions on Pattern Analysis and Machine Intelligence 28 (2006) 1568–1583. date_created: 2018-12-11T12:01:55Z date_published: 2006-08-21T00:00:00Z date_updated: 2021-01-12T07:41:41Z day: '21' doi: 10.1109/TPAMI.2006.200 extern: 1 intvolume: ' 28' issue: '10' main_file_link: - open_access: '0' url: http://research.microsoft.com/pubs/67371/trw_maxproduct_aistats05.pdf month: '08' page: 1568 - 1583 publication: IEEE Transactions on Pattern Analysis and Machine Intelligence publication_status: published publisher: IEEE publist_id: '3495' quality_controlled: 0 status: public title: Convergent tree reweighted message passing for energy minimization type: journal_article volume: 28 year: '2006' ... --- _id: '3188' abstract: - lang: eng text: 'We introduce the term cosegmentation which denotes the task of segmenting simultaneously the common parts of an image pair. A generative model for cosegmentation is presented. Inference in the model leads to minimizing an energy with an MRF term encoding spatial coherency and a global constraint which attempts to match the appearance histograms of the common parts. This energy has not been proposed previously and its optimization is challenging and NP-hard. For this problem a novel optimization scheme which we call trust region graph cuts is presented. We demonstrate that this framework has the potential to improve a wide range of research: Object driven image retrieval, video tracking and segmentation, and interactive image editing. The power of the framework lies in its generality, the common part can be a rigid/non-rigid object (or scene), observed from different viewpoints or even similar objects of the same class.' author: - first_name: Carsten full_name: Rother, Carsten last_name: Rother - first_name: Vladimir full_name: Vladimir Kolmogorov id: 3D50B0BA-F248-11E8-B48F-1D18A9856A87 last_name: Kolmogorov - first_name: Thomas full_name: Minka, Thomas P last_name: Minka - first_name: Andrew full_name: Blake, Andrew last_name: Blake citation: ama: 'Rother C, Kolmogorov V, Minka T, Blake A. Cosegmentation of image pairs by histogram matching - Incorporating a global constraint into MRFs. In: IEEE; 2006:993-1000. doi:10.1109/CVPR.2006.91' apa: 'Rother, C., Kolmogorov, V., Minka, T., & Blake, A. (2006). Cosegmentation of image pairs by histogram matching - Incorporating a global constraint into MRFs (pp. 993–1000). Presented at the CVPR: Computer Vision and Pattern Recognition, IEEE. https://doi.org/10.1109/CVPR.2006.91' chicago: Rother, Carsten, Vladimir Kolmogorov, Thomas Minka, and Andrew Blake. “Cosegmentation of Image Pairs by Histogram Matching - Incorporating a Global Constraint into MRFs,” 993–1000. IEEE, 2006. https://doi.org/10.1109/CVPR.2006.91. ieee: 'C. Rother, V. Kolmogorov, T. Minka, and A. Blake, “Cosegmentation of image pairs by histogram matching - Incorporating a global constraint into MRFs,” presented at the CVPR: Computer Vision and Pattern Recognition, 2006, pp. 993–1000.' ista: 'Rother C, Kolmogorov V, Minka T, Blake A. 2006. Cosegmentation of image pairs by histogram matching - Incorporating a global constraint into MRFs. CVPR: Computer Vision and Pattern Recognition, 993–1000.' mla: Rother, Carsten, et al. Cosegmentation of Image Pairs by Histogram Matching - Incorporating a Global Constraint into MRFs. IEEE, 2006, pp. 993–1000, doi:10.1109/CVPR.2006.91. short: C. Rother, V. Kolmogorov, T. Minka, A. Blake, in:, IEEE, 2006, pp. 993–1000. conference: name: 'CVPR: Computer Vision and Pattern Recognition' date_created: 2018-12-11T12:01:54Z date_published: 2006-07-05T00:00:00Z date_updated: 2021-01-12T07:41:40Z day: '05' doi: 10.1109/CVPR.2006.91 extern: 1 month: '07' page: 993 - 1000 publication_status: published publisher: IEEE publist_id: '3493' quality_controlled: 0 status: public title: Cosegmentation of image pairs by histogram matching - Incorporating a global constraint into MRFs type: conference year: '2006' ... --- _id: '3214' abstract: - lang: eng text: |- The Feistel-network is a popular structure underlying many block-ciphers where the cipher is constructed from many simpler rounds, each defined by some function which is derived from the secret key. Luby and Rackoff showed that the three-round Feistel-network – each round instantiated with a pseudorandom function secure against adaptive chosen plaintext attacks (CPA) – is a CPA secure pseudorandom permutation, thus giving some confidence in the soundness of using a Feistel-network to design block-ciphers. But the round functions used in actual block-ciphers are – for efficiency reasons – far from being pseudorandom. We investigate the security of the Feistel-network against CPA distinguishers when the only security guarantee we have for the round functions is that they are secure against non-adaptive chosen plaintext attacks (nCPA). We show that in the information-theoretic setting, four rounds with nCPA secure round functions are sufficient (and necessary) to get a CPA secure permutation. Unfortunately, this result does not translate into the more interesting pseudorandom setting. In fact, under the so-called Inverse Decisional Diffie-Hellman assumption the Feistel-network with four rounds, each instantiated with a nCPA secure pseudorandom function, is in general not a CPA secure pseudorandom permutation. acknowledgement: Most of this work was done while the K. Pietrzak was a PhD student at ETH where he was supported by the Swiss National Science Foundation, project No. 200020- 103847/1. Currently he is partially supported by the Commission of the European Communities through the IST program under contract IST-2002-507932 ECRYPT. alternative_title: - LNCS author: - first_name: Ueli full_name: Maurer, Ueli M last_name: Maurer - first_name: Yvonne full_name: Oswald, Yvonne A last_name: Oswald - first_name: Krzysztof Z full_name: Krzysztof Pietrzak id: 3E04A7AA-F248-11E8-B48F-1D18A9856A87 last_name: Pietrzak orcid: 0000-0002-9139-1654 - first_name: Johan full_name: Sjödin, Johan last_name: Sjödin citation: ama: 'Maurer U, Oswald Y, Pietrzak KZ, Sjödin J. Luby Rackoff ciphers from weak round functions . In: Vol 4004. Springer; 2006:391-408. doi:10.1007/11761679_24' apa: 'Maurer, U., Oswald, Y., Pietrzak, K. Z., & Sjödin, J. (2006). Luby Rackoff ciphers from weak round functions (Vol. 4004, pp. 391–408). Presented at the EUROCRYPT: Theory and Applications of Cryptographic Techniques, Springer. https://doi.org/10.1007/11761679_24' chicago: Maurer, Ueli, Yvonne Oswald, Krzysztof Z Pietrzak, and Johan Sjödin. “Luby Rackoff Ciphers from Weak Round Functions ,” 4004:391–408. Springer, 2006. https://doi.org/10.1007/11761679_24. ieee: 'U. Maurer, Y. Oswald, K. Z. Pietrzak, and J. Sjödin, “Luby Rackoff ciphers from weak round functions ,” presented at the EUROCRYPT: Theory and Applications of Cryptographic Techniques, 2006, vol. 4004, pp. 391–408.' ista: 'Maurer U, Oswald Y, Pietrzak KZ, Sjödin J. 2006. Luby Rackoff ciphers from weak round functions . EUROCRYPT: Theory and Applications of Cryptographic Techniques, LNCS, vol. 4004, 391–408.' mla: Maurer, Ueli, et al. Luby Rackoff Ciphers from Weak Round Functions . Vol. 4004, Springer, 2006, pp. 391–408, doi:10.1007/11761679_24. short: U. Maurer, Y. Oswald, K.Z. Pietrzak, J. Sjödin, in:, Springer, 2006, pp. 391–408. conference: name: 'EUROCRYPT: Theory and Applications of Cryptographic Techniques' date_created: 2018-12-11T12:02:03Z date_published: 2006-07-11T00:00:00Z date_updated: 2021-01-12T07:41:51Z day: '11' doi: 10.1007/11761679_24 extern: 1 intvolume: ' 4004' month: '07' page: 391 - 408 publication_status: published publisher: Springer publist_id: '3465' quality_controlled: 0 status: public title: 'Luby Rackoff ciphers from weak round functions ' type: conference volume: 4004 year: '2006' ... --- _id: '3215' abstract: - lang: eng text: 'Most cryptographic primitives such as encryption, authentication or secret sharing require randomness. Usually one assumes that perfect randomness is available, but those primitives might also be realized under weaker assumptions. In this work we continue the study of building secure cryptographic primitives from imperfect random sources initiated by Dodis and Spencer (FOCS’02). Their main result shows that there exists a (high-entropy) source of randomness allowing for perfect encryption of a bit, and yet from which one cannot extract even a single weakly random bit, separating encryption from extraction. Our main result separates encryption from 2-out-2 secret sharing (both in the information-theoretic and in the computational settings): any source which can be used to achieve one-bit encryption also can be used for 2-out-2 secret sharing of one bit, but the converse is false, even for high-entropy sources. Therefore, possibility of extraction strictly implies encryption, which in turn strictly implies 2-out-2 secret sharing.' acknowledgement: Supported in part by NSF career award CCR-0133806 and NSF grant CCR-0311095. Supported by the Swiss National Science Foundation, project No. 200020-103847/1. alternative_title: - LNCS author: - first_name: Yevgeniy full_name: Dodis, Yevgeniy last_name: Dodis - first_name: Krzysztof Z full_name: Krzysztof Pietrzak id: 3E04A7AA-F248-11E8-B48F-1D18A9856A87 last_name: Pietrzak orcid: 0000-0002-9139-1654 - first_name: Bartosz full_name: Przydatek, Bartosz last_name: Przydatek citation: ama: 'Dodis Y, Pietrzak KZ, Przydatek B. Separating sources for encryption and secret sharing. In: Vol 3876. Springer; 2006:601-616. doi:10.1007/11681878_31' apa: 'Dodis, Y., Pietrzak, K. Z., & Przydatek, B. (2006). Separating sources for encryption and secret sharing (Vol. 3876, pp. 601–616). Presented at the TCC: Theory of Cryptography Conference, Springer. https://doi.org/10.1007/11681878_31' chicago: Dodis, Yevgeniy, Krzysztof Z Pietrzak, and Bartosz Przydatek. “Separating Sources for Encryption and Secret Sharing,” 3876:601–16. Springer, 2006. https://doi.org/10.1007/11681878_31. ieee: 'Y. Dodis, K. Z. Pietrzak, and B. Przydatek, “Separating sources for encryption and secret sharing,” presented at the TCC: Theory of Cryptography Conference, 2006, vol. 3876, pp. 601–616.' ista: 'Dodis Y, Pietrzak KZ, Przydatek B. 2006. Separating sources for encryption and secret sharing. TCC: Theory of Cryptography Conference, LNCS, vol. 3876, 601–616.' mla: Dodis, Yevgeniy, et al. Separating Sources for Encryption and Secret Sharing. Vol. 3876, Springer, 2006, pp. 601–16, doi:10.1007/11681878_31. short: Y. Dodis, K.Z. Pietrzak, B. Przydatek, in:, Springer, 2006, pp. 601–616. conference: name: 'TCC: Theory of Cryptography Conference' date_created: 2018-12-11T12:02:04Z date_published: 2006-04-11T00:00:00Z date_updated: 2021-01-12T07:41:51Z day: '11' doi: 10.1007/11681878_31 extern: 1 intvolume: ' 3876' month: '04' page: 601 - 616 publication_status: published publisher: Springer publist_id: '3466' quality_controlled: 0 status: public title: Separating sources for encryption and secret sharing type: conference volume: 3876 year: '2006' ... --- _id: '3217' abstract: - lang: eng text: |- To prove that a secure key-agreement protocol exists one must at least show P ≠NP. Moreover any proof that the sequential composition of two non-adaptively secure pseudorandom functions is secure against at least two adaptive queries must falsify the decisional Diffie-Hellman assumption, a standard assumption from public-key cryptography. Hence proving any of this two seemingly unrelated statements would require a significant breakthrough. We show that at least one of the two statements is true. To our knowledge this gives the first positive cryptographic result (namely that composition implies some weak adaptive security) which holds in Minicrypt, but not in Cryptomania, i.e. under the assumption that one-way functions exist, but public-key cryptography does not. acknowledgement: Author was supported during the writing of this work by the Swiss National Science Foundation, project No. 200020-103847/1. Part of this work is supported by the Commission of the European Communities through the IST program under contract IST-2002-507932 alternative_title: - LNCS author: - first_name: Krzysztof Z full_name: Krzysztof Pietrzak id: 3E04A7AA-F248-11E8-B48F-1D18A9856A87 last_name: Pietrzak orcid: 0000-0002-9139-1654 citation: ama: 'Pietrzak KZ. Composition implies adaptive security in minicrypt. In: Vol 4004. Springer; 2006:328-338. doi:10.1007/11761679_20' apa: 'Pietrzak, K. Z. (2006). Composition implies adaptive security in minicrypt (Vol. 4004, pp. 328–338). Presented at the EUROCRYPT: Theory and Applications of Cryptographic Techniques, Springer. https://doi.org/10.1007/11761679_20' chicago: Pietrzak, Krzysztof Z. “Composition Implies Adaptive Security in Minicrypt,” 4004:328–38. Springer, 2006. https://doi.org/10.1007/11761679_20. ieee: 'K. Z. Pietrzak, “Composition implies adaptive security in minicrypt,” presented at the EUROCRYPT: Theory and Applications of Cryptographic Techniques, 2006, vol. 4004, pp. 328–338.' ista: 'Pietrzak KZ. 2006. Composition implies adaptive security in minicrypt. EUROCRYPT: Theory and Applications of Cryptographic Techniques, LNCS, vol. 4004, 328–338.' mla: Pietrzak, Krzysztof Z. Composition Implies Adaptive Security in Minicrypt. Vol. 4004, Springer, 2006, pp. 328–38, doi:10.1007/11761679_20. short: K.Z. Pietrzak, in:, Springer, 2006, pp. 328–338. conference: name: 'EUROCRYPT: Theory and Applications of Cryptographic Techniques' date_created: 2018-12-11T12:02:04Z date_published: 2006-07-11T00:00:00Z date_updated: 2021-01-12T07:41:52Z day: '11' doi: 10.1007/11761679_20 extern: 1 intvolume: ' 4004' month: '07' page: 328 - 338 publication_status: published publisher: Springer publist_id: '3464' quality_controlled: 0 status: public title: Composition implies adaptive security in minicrypt type: conference volume: 4004 year: '2006' ... --- _id: '3216' abstract: - lang: eng text: |- We prove a new upper bound on the advantage of any adversary for distinguishing the encrypted CBC-MAC (EMAC) based on random permutations from a random function. Our proof uses techniques recently introduced in [BPR05], which again were inspired by [DGH + 04]. The bound we prove is tight — in the sense that it matches the advantage of known attacks up to a constant factor — for a wide range of the parameters: let n denote the block-size, q the number of queries the adversary is allowed to make and ℓ an upper bound on the length (i.e. number of blocks) of the messages, then for ℓ ≤ 2 n/8 and q≥ł2 the advantage is in the order of q 2/2 n (and in particular independent of ℓ). This improves on the previous bound of q 2ℓΘ(1/ln ln ℓ)/2 n from [BPR05] and matches the trivial attack (which thus is basically optimal) where one simply asks random queries until a collision is found. acknowledgement: Part of this work is supported by the Commission of the European Communities through the IST program under contract IST-2002-507932 ECRYPT. alternative_title: - LNCS author: - first_name: Krzysztof Z full_name: Krzysztof Pietrzak id: 3E04A7AA-F248-11E8-B48F-1D18A9856A87 last_name: Pietrzak orcid: 0000-0002-9139-1654 citation: ama: 'Pietrzak KZ. A tight bound for EMAC. In: Vol 4052. Springer; 2006:168-179. doi:10.1007/11787006_15' apa: 'Pietrzak, K. Z. (2006). A tight bound for EMAC (Vol. 4052, pp. 168–179). Presented at the ICALP: Automata, Languages and Programming, Springer. https://doi.org/10.1007/11787006_15' chicago: Pietrzak, Krzysztof Z. “A Tight Bound for EMAC,” 4052:168–79. Springer, 2006. https://doi.org/10.1007/11787006_15. ieee: 'K. Z. Pietrzak, “A tight bound for EMAC,” presented at the ICALP: Automata, Languages and Programming, 2006, vol. 4052, pp. 168–179.' ista: 'Pietrzak KZ. 2006. A tight bound for EMAC. ICALP: Automata, Languages and Programming, LNCS, vol. 4052, 168–179.' mla: Pietrzak, Krzysztof Z. A Tight Bound for EMAC. Vol. 4052, Springer, 2006, pp. 168–79, doi:10.1007/11787006_15. short: K.Z. Pietrzak, in:, Springer, 2006, pp. 168–179. conference: name: 'ICALP: Automata, Languages and Programming' date_created: 2018-12-11T12:02:04Z date_published: 2006-07-28T00:00:00Z date_updated: 2021-01-12T07:41:52Z day: '28' doi: 10.1007/11787006_15 extern: 1 intvolume: ' 4052' month: '07' page: 168 - 179 publication_status: published publisher: Springer publist_id: '3463' quality_controlled: 0 status: public title: A tight bound for EMAC type: conference volume: 4052 year: '2006' ... --- _id: '3522' abstract: - lang: eng text: We observed sharp wave/ripples (SWR) during exploration within brief (< 2.4 s) interruptions of or during theta oscillations. CA1 network responses of SWRs occurring during exploration (eSWR) and SWRs detected in waking immobility or sleep were similar. However, neuronal activity during eSWR was location dependent, and eSWR-related firing was stronger inside the place field than outside. The eSPW-related firing increase was stronger than the baseline increase inside compared to outside, suggesting a “supralinear” summation of eSWR and place-selective inputs. Pairs of cells with similar place fields and/or correlated firing during exploration showed stronger coactivation during eSWRs and subsequent sleep-SWRs. Sequential activation of place cells was not required for the reactivation of waking co-firing patterns; cell pairs with symmetrical cross-correlations still showed reactivated waking co-firing patterns during sleep-SWRs. We suggest that place-selective firing during eSWRs facilitates initial associations between cells with similar place fields that enable place-related ensemble patterns to recur during subsequent sleep-SWRs. author: - first_name: Joseph full_name: Joseph O'Neill id: 426376DC-F248-11E8-B48F-1D18A9856A87 last_name: O'Neill - first_name: Timothy full_name: Senior,Timothy last_name: Senior - first_name: Jozsef L full_name: Jozsef Csicsvari id: 3FA14672-F248-11E8-B48F-1D18A9856A87 last_name: Csicsvari orcid: 0000-0002-5193-4036 citation: ama: O’Neill J, Senior T, Csicsvari JL. Place-selective firing of CA1 pyramidal cells during sharp wave/ripple network patterns in exploratory behavior. Neuron. 2006;49(1):143-155. doi:10.1016/j.neuron.2005.10.037 apa: O’Neill, J., Senior, T., & Csicsvari, J. L. (2006). Place-selective firing of CA1 pyramidal cells during sharp wave/ripple network patterns in exploratory behavior. Neuron. Elsevier. https://doi.org/10.1016/j.neuron.2005.10.037 chicago: O’Neill, Joseph, Timothy Senior, and Jozsef L Csicsvari. “Place-Selective Firing of CA1 Pyramidal Cells during Sharp Wave/Ripple Network Patterns in Exploratory Behavior.” Neuron. Elsevier, 2006. https://doi.org/10.1016/j.neuron.2005.10.037. ieee: J. O’Neill, T. Senior, and J. L. Csicsvari, “Place-selective firing of CA1 pyramidal cells during sharp wave/ripple network patterns in exploratory behavior,” Neuron, vol. 49, no. 1. Elsevier, pp. 143–155, 2006. ista: O’Neill J, Senior T, Csicsvari JL. 2006. Place-selective firing of CA1 pyramidal cells during sharp wave/ripple network patterns in exploratory behavior. Neuron. 49(1), 143–155. mla: O’Neill, Joseph, et al. “Place-Selective Firing of CA1 Pyramidal Cells during Sharp Wave/Ripple Network Patterns in Exploratory Behavior.” Neuron, vol. 49, no. 1, Elsevier, 2006, pp. 143–55, doi:10.1016/j.neuron.2005.10.037. short: J. O’Neill, T. Senior, J.L. Csicsvari, Neuron 49 (2006) 143–155. date_created: 2018-12-11T12:03:46Z date_published: 2006-01-05T00:00:00Z date_updated: 2021-01-12T07:44:03Z day: '05' doi: 10.1016/j.neuron.2005.10.037 extern: 1 intvolume: ' 49' issue: '1' month: '01' page: 143 - 155 publication: Neuron publication_status: published publisher: Elsevier publist_id: '2863' quality_controlled: 0 status: public title: Place-selective firing of CA1 pyramidal cells during sharp wave/ripple network patterns in exploratory behavior type: journal_article volume: 49 year: '2006' ... --- _id: '3607' abstract: - lang: eng text: We apply new analytical methods to understand the consequences of population bottlenecks for expected additive genetic variance. We analyze essentially all models for multilocus epistasis that have been numerically simulated to demonstrate increased additive variance. We conclude that for biologically plausible models, large increases in expected additive variance–attributable to epistasis rather than dominance–are unlikely. Naciri-Graven and Goudet (2003) found that as the number of epistatically interacting loci increases, additive variance tends to be inflated more after a bottleneck. We argue that this result reflects biologically unrealistic aspects of their models. Specifically, as the number of loci increases, higher-order epistatic interactions become increasingly important in these models, with an increasing fraction of the genetic variance becoming nonadditive, contrary to empirical observations. As shown by Barton and Turelli (2004), without dominance, conversion of nonadditive to additive variance depends only on the variance components and not on the number of loci per se. Numerical results indicating that more inbreeding is needed to produce maximal release of additive variance with more loci follow directly from our analytical results, which show that high levels of inbreeding (F > 0.5) are needed for significant conversion of higher-order components. We discuss alternative approaches to modeling multilocus epistasis and understanding its consequences. author: - first_name: Michael full_name: Turelli, Michael last_name: Turelli - first_name: Nicholas H full_name: Nicholas Barton id: 4880FE40-F248-11E8-B48F-1D18A9856A87 last_name: Barton orcid: 0000-0002-8548-5240 citation: ama: Turelli M, Barton NH. Will population bottlenecks and multilocus epistasis increase additive genetic variance? Evolution; International Journal of Organic Evolution. 2006;60(9):1763-1776. doi:10.1111/j.0014-3820.2006.tb00521.x apa: Turelli, M., & Barton, N. H. (2006). Will population bottlenecks and multilocus epistasis increase additive genetic variance? Evolution; International Journal of Organic Evolution. Wiley-Blackwell. https://doi.org/10.1111/j.0014-3820.2006.tb00521.x chicago: Turelli, Michael, and Nicholas H Barton. “Will Population Bottlenecks and Multilocus Epistasis Increase Additive Genetic Variance?” Evolution; International Journal of Organic Evolution. Wiley-Blackwell, 2006. https://doi.org/10.1111/j.0014-3820.2006.tb00521.x. ieee: M. Turelli and N. H. Barton, “Will population bottlenecks and multilocus epistasis increase additive genetic variance?,” Evolution; International Journal of Organic Evolution, vol. 60, no. 9. Wiley-Blackwell, pp. 1763–1776, 2006. ista: Turelli M, Barton NH. 2006. Will population bottlenecks and multilocus epistasis increase additive genetic variance? Evolution; International Journal of Organic Evolution. 60(9), 1763–1776. mla: Turelli, Michael, and Nicholas H. Barton. “Will Population Bottlenecks and Multilocus Epistasis Increase Additive Genetic Variance?” Evolution; International Journal of Organic Evolution, vol. 60, no. 9, Wiley-Blackwell, 2006, pp. 1763–76, doi:10.1111/j.0014-3820.2006.tb00521.x. short: M. Turelli, N.H. Barton, Evolution; International Journal of Organic Evolution 60 (2006) 1763–1776. date_created: 2018-12-11T12:04:13Z date_published: 2006-09-01T00:00:00Z date_updated: 2021-01-12T07:44:37Z day: '01' doi: 10.1111/j.0014-3820.2006.tb00521.x extern: 1 intvolume: ' 60' issue: '9' month: '09' page: 1763 - 1776 publication: Evolution; International Journal of Organic Evolution publication_status: published publisher: Wiley-Blackwell publist_id: '2776' quality_controlled: 0 status: public title: Will population bottlenecks and multilocus epistasis increase additive genetic variance? type: journal_article volume: 60 year: '2006' ... --- _id: '3683' abstract: - lang: eng text: Many algorithms to remove distortion from document images have be proposed in recent years, but so far there is no reliable method for comparing their performance. In this paper we propose a collection of methods to measure the quality of such restoration algorithms for document image which show a non-linear distortion due to perspective or page curl. For the result from these measurement to be meaningful, a common data set of ground truth is required. We therefore started with the buildup of a document image database that is meant to serve as a common data basis for all kinds of restoration from images of 3D-shaped document. The long term goal would be to establish this database and following extensions in the area of document image dewarping as an as fruitful and indispensable tool as e.g. the NIST database is for OCR, or the Caltech database is for object and face recognition. author: - first_name: Christoph full_name: Christoph Lampert id: 40C20FD2-F248-11E8-B48F-1D18A9856A87 last_name: Lampert orcid: 0000-0001-8622-7887 - first_name: Thomas full_name: Breuel,Thomas M last_name: Breuel citation: ama: 'Lampert C, Breuel T. Objective quality measurement for geometric document image restoration. In: Springer; 2006.' apa: 'Lampert, C., & Breuel, T. (2006). Objective quality measurement for geometric document image restoration. Presented at the DAS: Document Analysis Systems, Springer.' chicago: Lampert, Christoph, and Thomas Breuel. “Objective Quality Measurement for Geometric Document Image Restoration.” Springer, 2006. ieee: 'C. Lampert and T. Breuel, “Objective quality measurement for geometric document image restoration,” presented at the DAS: Document Analysis Systems, 2006.' ista: 'Lampert C, Breuel T. 2006. Objective quality measurement for geometric document image restoration. DAS: Document Analysis Systems.' mla: Lampert, Christoph, and Thomas Breuel. Objective Quality Measurement for Geometric Document Image Restoration. Springer, 2006. short: C. Lampert, T. Breuel, in:, Springer, 2006. conference: name: 'DAS: Document Analysis Systems' date_created: 2018-12-11T12:04:36Z date_published: 2006-03-16T00:00:00Z date_updated: 2021-01-12T07:45:07Z day: '16' extern: 1 main_file_link: - open_access: '0' url: http://pub.ist.ac.at/~chl/papers/lampert-das2006.pdf month: '03' publication_status: published publisher: Springer publist_id: '2692' quality_controlled: 0 status: public title: Objective quality measurement for geometric document image restoration type: conference year: '2006' ... --- _id: '3685' abstract: - lang: eng text: 'Video compression currently is dominated by engineering and fine-tuned heuristic methods. In this paper, we propose to instead apply the well-developed machinery of machine learning in order to support the optimization of existing video encoders and the creation of new ones. Exemplarily, we show how by machine learning we can improve one encoding step that is crucial for the performance of all current video standards: macroblock mode decision. By formulating the problem in a Bayesian setup, we show that macroblock mode decision can be reduced to a classification problem with a cost function for misclassification that is sample dependent. We demonstrate how to apply different machine learning techniques to obtain suitable classifiers and we show in detailed experiments that all of these perform better than the state-of-the-art heuristic method' author: - first_name: Christoph full_name: Christoph Lampert id: 40C20FD2-F248-11E8-B48F-1D18A9856A87 last_name: Lampert orcid: 0000-0001-8622-7887 citation: ama: 'Lampert C. Machine learning for video compression: Macroblock mode decision. In: IEEE; 2006:936-940. doi:10.1109/ICPR.2006.778' apa: 'Lampert, C. (2006). Machine learning for video compression: Macroblock mode decision (pp. 936–940). Presented at the ICPR: International Conference on Pattern Recognition, IEEE. https://doi.org/10.1109/ICPR.2006.778' chicago: 'Lampert, Christoph. “Machine Learning for Video Compression: Macroblock Mode Decision,” 936–40. IEEE, 2006. https://doi.org/10.1109/ICPR.2006.778.' ieee: 'C. Lampert, “Machine learning for video compression: Macroblock mode decision,” presented at the ICPR: International Conference on Pattern Recognition, 2006, pp. 936–940.' ista: 'Lampert C. 2006. Machine learning for video compression: Macroblock mode decision. ICPR: International Conference on Pattern Recognition, 936–940.' mla: 'Lampert, Christoph. Machine Learning for Video Compression: Macroblock Mode Decision. IEEE, 2006, pp. 936–40, doi:10.1109/ICPR.2006.778.' short: C. Lampert, in:, IEEE, 2006, pp. 936–940. conference: name: 'ICPR: International Conference on Pattern Recognition' date_created: 2018-12-11T12:04:37Z date_published: 2006-09-18T00:00:00Z date_updated: 2021-01-12T07:45:08Z day: '18' doi: 10.1109/ICPR.2006.778 extern: 1 month: '09' page: 936 - 940 publication_status: published publisher: IEEE publist_id: '2689' quality_controlled: 0 status: public title: 'Machine learning for video compression: Macroblock mode decision' type: conference year: '2006' ... --- _id: '3750' abstract: - lang: eng text: We applied a single-cell assay to characterize how transcription dynamics affects protein expression levels of a tetracycline-inducible gene expression system. Transcriptional activity of the tetracycline promoter in response to a steady level of inducer is steady in ΔacrAB efflux mutant but pulsating in wildtype Escherichia coli cells. We found that the expression level of the green fluorescent protein is several folds higher in ΔacrAB efflux mutant than in wildtype cells. author: - first_name: Thuc full_name: Le,Thuc T. last_name: Le - first_name: Calin C full_name: Calin Guet id: 47F8433E-F248-11E8-B48F-1D18A9856A87 last_name: Guet orcid: 0000-0001-6220-2052 - first_name: Philippe full_name: Cluzel,Philippe last_name: Cluzel citation: ama: Le T, Guet CC, Cluzel P. Protein expression enhancement in efflux-deleted mutant bacteria. Protein Expression and Purification. 2006;48(1):28-31. apa: Le, T., Guet, C. C., & Cluzel, P. (2006). Protein expression enhancement in efflux-deleted mutant bacteria. Protein Expression and Purification. Elsevier. chicago: Le, Thuc, Calin C Guet, and Philippe Cluzel. “Protein Expression Enhancement in Efflux-Deleted Mutant Bacteria.” Protein Expression and Purification. Elsevier, 2006. ieee: T. Le, C. C. Guet, and P. Cluzel, “Protein expression enhancement in efflux-deleted mutant bacteria,” Protein Expression and Purification, vol. 48, no. 1. Elsevier, pp. 28–31, 2006. ista: Le T, Guet CC, Cluzel P. 2006. Protein expression enhancement in efflux-deleted mutant bacteria. Protein Expression and Purification. 48(1), 28–31. mla: Le, Thuc, et al. “Protein Expression Enhancement in Efflux-Deleted Mutant Bacteria.” Protein Expression and Purification, vol. 48, no. 1, Elsevier, 2006, pp. 28–31. short: T. Le, C.C. Guet, P. Cluzel, Protein Expression and Purification 48 (2006) 28–31. date_created: 2018-12-11T12:04:58Z date_published: 2006-07-01T00:00:00Z date_updated: 2021-01-12T07:51:56Z day: '01' extern: 1 intvolume: ' 48' issue: '1' month: '07' page: 28 - 31 publication: Protein Expression and Purification publication_status: published publisher: Elsevier publist_id: '2478' quality_controlled: 0 status: public title: Protein expression enhancement in efflux-deleted mutant bacteria type: journal_article volume: 48 year: '2006' ... --- _id: '3767' abstract: - lang: eng text: Models of RNA secondary structure folding are widely used to study evolution in theory and simulation. However, systematic studies of the parameters involved are rare. In this paper, we study by simulation how RNA evolution is influenced by three different factors, namely the mutation rate, scaling of the fitness function, and distance measure. We found that for low mutation rates the qualitative evolutionary behavior is robust with respect to the scaling of the fitness function. For efficient mutation rates, which are close to the error threshold, scaling and distance measure have a strong influence on the evolutionary behavior. A global distance measure that takes sequence information additively into account lowers the error threshold. When using a local sequence-structure alignment for the distance, we observed a smoother evolution of the fitness over time. Finally, in addition to the well known error threshold, we identify another threshold of the mutation rate, called divergence threshold, where the qualitative transient behavior changes from a localized to an exploratory search. author: - first_name: Anne full_name: Anne Kupczok id: 2BB22BC2-F248-11E8-B48F-1D18A9856A87 last_name: Kupczok - first_name: Peter full_name: Dittrich,Peter last_name: Dittrich citation: ama: Kupczok A, Dittrich P. Determinants of simulated RNA evolution. Journal of Theoretical Biology. 2006;238(3):726-735. doi:10.1016/j.jtbi.2005.06.019 apa: Kupczok, A., & Dittrich, P. (2006). Determinants of simulated RNA evolution. Journal of Theoretical Biology. Elsevier. https://doi.org/10.1016/j.jtbi.2005.06.019 chicago: Kupczok, Anne, and Peter Dittrich. “Determinants of Simulated RNA Evolution.” Journal of Theoretical Biology. Elsevier, 2006. https://doi.org/10.1016/j.jtbi.2005.06.019. ieee: A. Kupczok and P. Dittrich, “Determinants of simulated RNA evolution.,” Journal of Theoretical Biology, vol. 238, no. 3. Elsevier, pp. 726–35, 2006. ista: Kupczok A, Dittrich P. 2006. Determinants of simulated RNA evolution. Journal of Theoretical Biology. 238(3), 726–35. mla: Kupczok, Anne, and Peter Dittrich. “Determinants of Simulated RNA Evolution.” Journal of Theoretical Biology, vol. 238, no. 3, Elsevier, 2006, pp. 726–35, doi:10.1016/j.jtbi.2005.06.019. short: A. Kupczok, P. Dittrich, Journal of Theoretical Biology 238 (2006) 726–35. date_created: 2018-12-11T12:05:03Z date_published: 2006-01-01T00:00:00Z date_updated: 2021-01-12T07:52:03Z day: '01' doi: 10.1016/j.jtbi.2005.06.019 extern: 1 intvolume: ' 238' issue: '3' month: '01' page: 726 - 35 publication: Journal of Theoretical Biology publication_status: published publisher: Elsevier publist_id: '2461' quality_controlled: 0 status: public title: Determinants of simulated RNA evolution. type: journal_article volume: 238 year: '2006' ... --- _id: '3813' abstract: - lang: eng text: Hyperpolarization-activated channels (Ih or HCN channels) are widely expressed in principal neurons in the central nervous system. However, Ih in inhibitory GABAergic interneurons is less well characterized. We examined the functional properties of Ih in fast-spiking basket cells (BCs) of the dentate gyrus, using hippocampal slices from 17- to 21-day-old rats. Bath application of the Ih channel blocker ZD 7288 at a concentration of 30 microm induced a hyperpolarization of 5.7 +/- 1.5 mV, an increase in input resistance and a correlated increase in apparent membrane time constant. ZD 7288 blocked a hyperpolarization-activated current in a concentration-dependent manner (IC50, 1.4 microm). The effects of ZD 7288 were mimicked by external Cs+. The reversal potential of Ih was -27.4 mV, corresponding to a Na+ to K+ permeability ratio (PNa/PK) of 0.36. The midpoint potential of the activation curve of Ih was -83.9 mV, and the activation time constant at -120 mV was 190 ms. Single-cell expression analysis using reverse transcription followed by quantitative polymerase chain reaction revealed that BCs coexpress HCN1 and HCN2 subunit mRNA, suggesting the formation of heteromeric HCN1/2 channels. ZD 7288 increased the current threshold for evoking antidromic action potentials by extracellular stimulation, consistent with the expression of Ih in BC axons. Finally, ZD 7288 decreased the frequency of miniature inhibitory postsynaptic currents (mIPSCs) in hippocampal granule cells, the main target cells of BCs, to 70 +/- 4% of the control value. In contrast, the amplitude of mIPSCs was unchanged, consistent with the presence of Ih in inhibitory terminals. In conclusion, our results suggest that Ih channels are expressed in the somatodendritic region, axon and presynaptic elements of fast-spiking BCs in the hippocampus. author: - first_name: Yexica full_name: Aponte, Yexica last_name: Aponte - first_name: Cheng full_name: Lien, Cheng-Chang last_name: Lien - first_name: Ellen full_name: Reisinger, Ellen last_name: Reisinger - first_name: Peter M full_name: Peter Jonas id: 353C1B58-F248-11E8-B48F-1D18A9856A87 last_name: Jonas orcid: 0000-0001-5001-4804 citation: ama: Aponte Y, Lien C, Reisinger E, Jonas PM. Hyperpolarization-activated cation channels in fast-spiking interneurons of rat hippocampus. Journal of Physiology. 2006;574(Pt 1):229-243. doi:10.1113/jphysiol.2005.104042 apa: Aponte, Y., Lien, C., Reisinger, E., & Jonas, P. M. (2006). Hyperpolarization-activated cation channels in fast-spiking interneurons of rat hippocampus. Journal of Physiology. Wiley-Blackwell. https://doi.org/10.1113/jphysiol.2005.104042 chicago: Aponte, Yexica, Cheng Lien, Ellen Reisinger, and Peter M Jonas. “Hyperpolarization-Activated Cation Channels in Fast-Spiking Interneurons of Rat Hippocampus.” Journal of Physiology. Wiley-Blackwell, 2006. https://doi.org/10.1113/jphysiol.2005.104042. ieee: Y. Aponte, C. Lien, E. Reisinger, and P. M. Jonas, “Hyperpolarization-activated cation channels in fast-spiking interneurons of rat hippocampus,” Journal of Physiology, vol. 574, no. Pt 1. Wiley-Blackwell, pp. 229–43, 2006. ista: Aponte Y, Lien C, Reisinger E, Jonas PM. 2006. Hyperpolarization-activated cation channels in fast-spiking interneurons of rat hippocampus. Journal of Physiology. 574(Pt 1), 229–43. mla: Aponte, Yexica, et al. “Hyperpolarization-Activated Cation Channels in Fast-Spiking Interneurons of Rat Hippocampus.” Journal of Physiology, vol. 574, no. Pt 1, Wiley-Blackwell, 2006, pp. 229–43, doi:10.1113/jphysiol.2005.104042. short: Y. Aponte, C. Lien, E. Reisinger, P.M. Jonas, Journal of Physiology 574 (2006) 229–43. date_created: 2018-12-11T12:05:19Z date_published: 2006-01-01T00:00:00Z date_updated: 2021-01-12T07:52:23Z day: '01' doi: 10.1113/jphysiol.2005.104042 extern: 1 intvolume: ' 574' issue: Pt 1 main_file_link: - open_access: '1' url: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1817792/ month: '01' oa: 1 page: 229 - 43 publication: Journal of Physiology publication_status: published publisher: Wiley-Blackwell publist_id: '2397' quality_controlled: 0 status: public title: Hyperpolarization-activated cation channels in fast-spiking interneurons of rat hippocampus type: journal_article volume: 574 year: '2006' ... --- _id: '3814' abstract: - lang: eng text: The axon terminals (mossy fibers) of hippocampal dentate granule cells form characteristic synaptic connections with large spines or excrescences of both hilar mossy cells and CA3 pyramidal neurons. Interneurons of the hilar region and area CA3 are also prominent targets of mossy fibers. The tracing of biocytin-filled mossy fibers and immunolabeling of target cells with interneuron markers has revealed that the majority of mossy fiber synapses project to gamma aminobutyric acid (GABA)-ergic inhibitory interneurons rather than to excitatory principal cells, although the functional implications of these quantitative differences are unclear. Following a brief description of the "classical" mossy fiber synapse on excrescences of CA3 pyramidal cells, the present review focuses on the contacts formed between granule cells and GABAergic interneurons, both normally and after synaptic reorganization. In response to deafferentation of mossy cell target cells, which include both granule cells and interneurons, mossy fibers "sprout" new axon collaterals that form a band of supragranular mossy fibers in the inner molecular layer of the dentate gyrus. Although most newly formed recurrent mossy fibers establish synapses with granule cells, there is an apparently convergent input of new mossy fibers onto GABA-immunoreactive interneuron dendrites that traverse the inner molecular layer. These mossy fiber-interneuron synapses in the dentate gyrus are observed in chronically epileptic rats and may be the structural correlate of the granule cell hyperinhibition observed in these animals in vivo. Together, the findings reviewed here establish mossy fiber synapses as an important component of inhibitory circuits in the hippocampus. author: - first_name: Michael full_name: Frotscher, Michael last_name: Frotscher - first_name: Peter M full_name: Peter Jonas id: 353C1B58-F248-11E8-B48F-1D18A9856A87 last_name: Jonas orcid: 0000-0001-5001-4804 - first_name: Robert full_name: Sloviter, Robert S last_name: Sloviter citation: ama: Frotscher M, Jonas PM, Sloviter R. Synapses formed by normal and abnormal hippocampal mossy fibers (Review). Cell and Tissue Research. 2006;326(2):361-367. doi:10.1007/s00441-006-0269-2 apa: Frotscher, M., Jonas, P. M., & Sloviter, R. (2006). Synapses formed by normal and abnormal hippocampal mossy fibers (Review). Cell and Tissue Research. Springer. https://doi.org/10.1007/s00441-006-0269-2 chicago: Frotscher, Michael, Peter M Jonas, and Robert Sloviter. “Synapses Formed by Normal and Abnormal Hippocampal Mossy Fibers (Review).” Cell and Tissue Research. Springer, 2006. https://doi.org/10.1007/s00441-006-0269-2. ieee: M. Frotscher, P. M. Jonas, and R. Sloviter, “Synapses formed by normal and abnormal hippocampal mossy fibers (Review),” Cell and Tissue Research, vol. 326, no. 2. Springer, pp. 361–7, 2006. ista: Frotscher M, Jonas PM, Sloviter R. 2006. Synapses formed by normal and abnormal hippocampal mossy fibers (Review). Cell and Tissue Research. 326(2), 361–7. mla: Frotscher, Michael, et al. “Synapses Formed by Normal and Abnormal Hippocampal Mossy Fibers (Review).” Cell and Tissue Research, vol. 326, no. 2, Springer, 2006, pp. 361–67, doi:10.1007/s00441-006-0269-2. short: M. Frotscher, P.M. Jonas, R. Sloviter, Cell and Tissue Research 326 (2006) 361–7. date_created: 2018-12-11T12:05:19Z date_published: 2006-01-01T00:00:00Z date_updated: 2019-04-26T07:22:35Z day: '01' doi: 10.1007/s00441-006-0269-2 extern: 1 intvolume: ' 326' issue: '2' month: '01' page: 361 - 7 publication: Cell and Tissue Research publication_status: published publisher: Springer publist_id: '2395' quality_controlled: 0 status: public title: Synapses formed by normal and abnormal hippocampal mossy fibers (Review) type: review volume: 326 year: '2006' ... --- _id: '3815' abstract: - lang: eng text: It is widely accepted that the hippocampus plays a major role in learning and memory. The mossy fiber synapse between granule cells in the dentate gyrus and pyramidal neurons in the CA3 region is a key component of the hippocampal trisynaptic circuit. Recent work, partially based on direct presynaptic patch-clamp recordings from hippocampal mossy fiber boutons, sheds light on the mechanisms of synaptic transmission and plasticity at mossy fiber synapses. A high Na(+) channel density in mossy fiber boutons leads to a large amplitude of the presynaptic action potential. Together with the fast gating of presynaptic Ca(2+) channels, this generates a large and brief presynaptic Ca(2+) influx, which can trigger transmitter release with high efficiency and temporal precision. The large number of release sites, the large size of the releasable pool of vesicles, and the huge extent of presynaptic plasticity confer unique strength to this synapse, suggesting a large impact onto the CA3 pyramidal cell network under specific behavioral conditions. The characteristic properties of the hippocampal mossy fiber synapse may be important for pattern separation and information storage in the dentate gyrus-CA3 cell network. author: - first_name: Josef full_name: Bischofberger, Josef last_name: Bischofberger - first_name: Dominique full_name: Engel, Dominique last_name: Engel - first_name: Michael full_name: Frotscher, Michael last_name: Frotscher - first_name: Peter M full_name: Peter Jonas id: 353C1B58-F248-11E8-B48F-1D18A9856A87 last_name: Jonas orcid: 0000-0001-5001-4804 citation: ama: 'Bischofberger J, Engel D, Frotscher M, Jonas PM. Timing and efficacy of transmitter release at mossy fiber synapses in the hippocampal network. Pflugers Archiv : European Journal of Physiology. 2006;453(3):361-372. doi:10.1007/s00424-006-0093-2' apa: 'Bischofberger, J., Engel, D., Frotscher, M., & Jonas, P. M. (2006). Timing and efficacy of transmitter release at mossy fiber synapses in the hippocampal network. Pflugers Archiv : European Journal of Physiology. Springer. https://doi.org/10.1007/s00424-006-0093-2' chicago: 'Bischofberger, Josef, Dominique Engel, Michael Frotscher, and Peter M Jonas. “Timing and Efficacy of Transmitter Release at Mossy Fiber Synapses in the Hippocampal Network.” Pflugers Archiv : European Journal of Physiology. Springer, 2006. https://doi.org/10.1007/s00424-006-0093-2.' ieee: 'J. Bischofberger, D. Engel, M. Frotscher, and P. M. Jonas, “Timing and efficacy of transmitter release at mossy fiber synapses in the hippocampal network,” Pflugers Archiv : European Journal of Physiology, vol. 453, no. 3. Springer, pp. 361–72, 2006.' ista: 'Bischofberger J, Engel D, Frotscher M, Jonas PM. 2006. Timing and efficacy of transmitter release at mossy fiber synapses in the hippocampal network. Pflugers Archiv : European Journal of Physiology. 453(3), 361–72.' mla: 'Bischofberger, Josef, et al. “Timing and Efficacy of Transmitter Release at Mossy Fiber Synapses in the Hippocampal Network.” Pflugers Archiv : European Journal of Physiology, vol. 453, no. 3, Springer, 2006, pp. 361–72, doi:10.1007/s00424-006-0093-2.' short: 'J. Bischofberger, D. Engel, M. Frotscher, P.M. Jonas, Pflugers Archiv : European Journal of Physiology 453 (2006) 361–72.' date_created: 2018-12-11T12:05:19Z date_published: 2006-01-01T00:00:00Z date_updated: 2021-01-12T07:52:24Z day: '01' doi: 10.1007/s00424-006-0093-2 extern: 1 intvolume: ' 453' issue: '3' month: '01' page: 361 - 72 publication: 'Pflugers Archiv : European Journal of Physiology' publication_status: published publisher: Springer publist_id: '2396' quality_controlled: 0 status: public title: Timing and efficacy of transmitter release at mossy fiber synapses in the hippocampal network type: journal_article volume: 453 year: '2006' ... --- _id: '3811' abstract: - lang: eng text: Networks of GABAergic neurons are key elements in the generation of gamma oscillations in the brain. Computational studies suggested that the emergence of coherent oscillations requires hyperpolarizing inhibition. Here, we show that GABA(A) receptor-mediated inhibition in mature interneurons of the hippocampal dentate gyrus is shunting rather than hyperpolarizing. Unexpectedly, when shunting inhibition is incorporated into a structured interneuron network model with fast and strong synapses, coherent oscillations emerge. In comparison to hyperpolarizing inhibition, networks with shunting inhibition show several advantages. First, oscillations are generated with smaller tonic excitatory drive. Second, network frequencies are tuned to the gamma band. Finally, robustness against heterogeneity in the excitatory drive is markedly improved. In single interneurons, shunting inhibition shortens the interspike interval for low levels of drive but prolongs it for high levels, leading to homogenization of neuronal firing rates. Thus, shunting inhibition may confer increased robustness to gamma oscillations in the brain. author: - first_name: Imre full_name: Vida, Imre last_name: Vida - first_name: Marlene full_name: Bartos, Marlene last_name: Bartos - first_name: Peter M full_name: Peter Jonas id: 353C1B58-F248-11E8-B48F-1D18A9856A87 last_name: Jonas orcid: 0000-0001-5001-4804 citation: ama: Vida I, Bartos M, Jonas PM. Shunting inhibition improves robustness of gamma oscillations in hippocampal interneuron networks by homogenizing firing rates. Neuron. 2006;49(1):107-117. doi:10.1016/j.neuron.2005.11.036 apa: Vida, I., Bartos, M., & Jonas, P. M. (2006). Shunting inhibition improves robustness of gamma oscillations in hippocampal interneuron networks by homogenizing firing rates. Neuron. Elsevier. https://doi.org/10.1016/j.neuron.2005.11.036 chicago: Vida, Imre, Marlene Bartos, and Peter M Jonas. “Shunting Inhibition Improves Robustness of Gamma Oscillations in Hippocampal Interneuron Networks by Homogenizing Firing Rates.” Neuron. Elsevier, 2006. https://doi.org/10.1016/j.neuron.2005.11.036. ieee: I. Vida, M. Bartos, and P. M. Jonas, “Shunting inhibition improves robustness of gamma oscillations in hippocampal interneuron networks by homogenizing firing rates,” Neuron, vol. 49, no. 1. Elsevier, pp. 107–17, 2006. ista: Vida I, Bartos M, Jonas PM. 2006. Shunting inhibition improves robustness of gamma oscillations in hippocampal interneuron networks by homogenizing firing rates. Neuron. 49(1), 107–17. mla: Vida, Imre, et al. “Shunting Inhibition Improves Robustness of Gamma Oscillations in Hippocampal Interneuron Networks by Homogenizing Firing Rates.” Neuron, vol. 49, no. 1, Elsevier, 2006, pp. 107–17, doi:10.1016/j.neuron.2005.11.036. short: I. Vida, M. Bartos, P.M. Jonas, Neuron 49 (2006) 107–17. date_created: 2018-12-11T12:05:18Z date_published: 2006-01-01T00:00:00Z date_updated: 2021-01-12T07:52:22Z day: '01' doi: 10.1016/j.neuron.2005.11.036 extern: 1 intvolume: ' 49' issue: '1' month: '01' page: 107 - 17 publication: Neuron publication_status: published publisher: Elsevier publist_id: '2398' quality_controlled: 0 status: public title: Shunting inhibition improves robustness of gamma oscillations in hippocampal interneuron networks by homogenizing firing rates type: journal_article volume: 49 year: '2006' ... --- _id: '3817' author: - first_name: Michael full_name: Frotscher, Michael last_name: Frotscher - first_name: Eckart full_name: Gundelfinger, Eckart last_name: Gundelfinger - first_name: Peter M full_name: Peter Jonas id: 353C1B58-F248-11E8-B48F-1D18A9856A87 last_name: Jonas orcid: 0000-0001-5001-4804 - first_name: Erwin full_name: Neher, Erwin last_name: Neher - first_name: Peter full_name: Seeburg, Peter last_name: Seeburg citation: ama: Frotscher M, Gundelfinger E, Jonas PM, Neher E, Seeburg P. The most important recent advances in synapse research from my point of view--and what remains to be done. Cell and Tissue Research. 2006;326(2):203-204. doi:10.1007/s00441-006-0325-y apa: Frotscher, M., Gundelfinger, E., Jonas, P. M., Neher, E., & Seeburg, P. (2006). The most important recent advances in synapse research from my point of view--and what remains to be done. Cell and Tissue Research. Springer. https://doi.org/10.1007/s00441-006-0325-y chicago: Frotscher, Michael, Eckart Gundelfinger, Peter M Jonas, Erwin Neher, and Peter Seeburg. “The Most Important Recent Advances in Synapse Research from My Point of View--and What Remains to Be Done.” Cell and Tissue Research. Springer, 2006. https://doi.org/10.1007/s00441-006-0325-y. ieee: M. Frotscher, E. Gundelfinger, P. M. Jonas, E. Neher, and P. Seeburg, “The most important recent advances in synapse research from my point of view--and what remains to be done,” Cell and Tissue Research, vol. 326, no. 2. Springer, pp. 203–4, 2006. ista: Frotscher M, Gundelfinger E, Jonas PM, Neher E, Seeburg P. 2006. The most important recent advances in synapse research from my point of view--and what remains to be done. Cell and Tissue Research. 326(2), 203–4. mla: Frotscher, Michael, et al. “The Most Important Recent Advances in Synapse Research from My Point of View--and What Remains to Be Done.” Cell and Tissue Research, vol. 326, no. 2, Springer, 2006, pp. 203–04, doi:10.1007/s00441-006-0325-y. short: M. Frotscher, E. Gundelfinger, P.M. Jonas, E. Neher, P. Seeburg, Cell and Tissue Research 326 (2006) 203–4. date_created: 2018-12-11T12:05:20Z date_published: 2006-01-01T00:00:00Z date_updated: 2021-01-12T07:52:24Z day: '01' doi: 10.1007/s00441-006-0325-y extern: 1 intvolume: ' 326' issue: '2' month: '01' page: 203 - 4 publication: Cell and Tissue Research publication_status: published publisher: Springer publist_id: '2394' quality_controlled: 0 status: public title: The most important recent advances in synapse research from my point of view--and what remains to be done type: journal_article volume: 326 year: '2006' ... --- _id: '3912' abstract: - lang: eng text: Invasive species often dramatically change native species communities by directly and indirectly out-competing native species. We studied the direct interference abilities of the invasive garden ant, Lasius neglectus VAN LOON, BOOMSMA & ANDRÁSFALVY, 1990, by performing one-to-one aggression tests of L. neglectus workers towards three native Lasius ant species that occur at the edge of a L. neglectus supercolony in Seva, Spain. Our results show that L. neglectus is highly aggressive against all three native Lasius species tested (L. grandis FOREL, 1909, L. emarginatus (OLIVIER, 1792), and L. cinereus SEIFERT, 1992), expressed as a higher attack rate of L. neglectus and behavioural dominance throughout the aggressive encounters. Attacks of L. neglectus were performed fastest and most frequent against L. grandis, and also the highest antennation frequencies were observed in encounters between these two species. This could be due to the largest difference in body size, or due to a greater overlap in ecological niche between L. neglectus and L. grandis compared to the other two native species. There was only weak support for L. neglectus workers from the periphery of the supercolony to be more aggressive relative to workers from the centre, even though the former encounter native ant species on a daily basis at the edge of the supercolony. author: - first_name: Sylvia full_name: Cremer, Sylvia id: 2F64EC8C-F248-11E8-B48F-1D18A9856A87 last_name: Cremer orcid: 0000-0002-2193-3868 - first_name: Line V full_name: Ugelvig, Line V id: 3DC97C8E-F248-11E8-B48F-1D18A9856A87 last_name: Ugelvig orcid: 0000-0003-1832-8883 - first_name: Suzanne full_name: Lommen, Suzanne last_name: Lommen - first_name: Klaus full_name: Petersen, Klaus last_name: Petersen - first_name: Jes full_name: Pedersen, Jes last_name: Pedersen citation: ama: 'Cremer S, Ugelvig LV, Lommen S, Petersen K, Pedersen J. Attack of the invasive garden ant: aggression behaviour of Lasius neglectus (Hymenoptera: Formicidae) against native Lasius species in Spain. Myrmecological News. 2006;9:13-19.' apa: 'Cremer, S., Ugelvig, L. V., Lommen, S., Petersen, K., & Pedersen, J. (2006). Attack of the invasive garden ant: aggression behaviour of Lasius neglectus (Hymenoptera: Formicidae) against native Lasius species in Spain. Myrmecological News. Österreichische Gesellschaft für Entomofaunistik.' chicago: 'Cremer, Sylvia, Line V Ugelvig, Suzanne Lommen, Klaus Petersen, and Jes Pedersen. “Attack of the Invasive Garden Ant: Aggression Behaviour of Lasius Neglectus (Hymenoptera: Formicidae) against Native Lasius Species in Spain.” Myrmecological News. Österreichische Gesellschaft für Entomofaunistik, 2006.' ieee: 'S. Cremer, L. V. Ugelvig, S. Lommen, K. Petersen, and J. Pedersen, “Attack of the invasive garden ant: aggression behaviour of Lasius neglectus (Hymenoptera: Formicidae) against native Lasius species in Spain,” Myrmecological News, vol. 9. Österreichische Gesellschaft für Entomofaunistik, pp. 13–19, 2006.' ista: 'Cremer S, Ugelvig LV, Lommen S, Petersen K, Pedersen J. 2006. Attack of the invasive garden ant: aggression behaviour of Lasius neglectus (Hymenoptera: Formicidae) against native Lasius species in Spain. Myrmecological News. 9, 13–19.' mla: 'Cremer, Sylvia, et al. “Attack of the Invasive Garden Ant: Aggression Behaviour of Lasius Neglectus (Hymenoptera: Formicidae) against Native Lasius Species in Spain.” Myrmecological News, vol. 9, Österreichische Gesellschaft für Entomofaunistik, 2006, pp. 13–19.' short: S. Cremer, L.V. Ugelvig, S. Lommen, K. Petersen, J. Pedersen, Myrmecological News 9 (2006) 13–19. date_created: 2018-12-11T12:05:51Z date_published: 2006-12-01T00:00:00Z date_updated: 2021-01-12T07:53:09Z day: '01' extern: '1' intvolume: ' 9' language: - iso: eng month: '12' oa_version: None page: 13 - 19 publication: Myrmecological News publication_status: published publisher: Österreichische Gesellschaft für Entomofaunistik publist_id: '2239' status: public title: 'Attack of the invasive garden ant: aggression behaviour of Lasius neglectus (Hymenoptera: Formicidae) against native Lasius species in Spain' type: journal_article user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87 volume: 9 year: '2006' ... --- _id: '3914' abstract: - lang: eng text: We compare the performances of established means of character selection for discriminant analysis in species distinction with a combination procedure for finding the optimal character combination (minimum classification error, minimum number of required characters), using morphometric data sets from the ant genera Cardiocondyla, Lasius and Tetramorium. The established methods are empirical character selection as well as forward selection, backward elimination and stepwise selection of discriminant analysis. The combination procedure is clearly superior to the established methods of character selection, and is widely applicable. author: - first_name: Karl full_name: Moder, Karl last_name: Moder - first_name: Birgit full_name: Schlick Steiner, Birgit last_name: Schlick Steiner - first_name: Florian full_name: Steiner, Florian last_name: Steiner - first_name: Sylvia full_name: Cremer, Sylvia id: 2F64EC8C-F248-11E8-B48F-1D18A9856A87 last_name: Cremer orcid: 0000-0002-2193-3868 - first_name: Erhard full_name: Christian, Erhard last_name: Christian - first_name: Bernhard full_name: Seifert, Bernhard last_name: Seifert citation: ama: 'Moder K, Schlick Steiner B, Steiner F, Cremer S, Christian E, Seifert B. Optimal species distinction by discriminant analysis: comparing established methods of character selection with a combination procedure using ant morphometrics as a case study. Journal of Zoological Systematics and Evolutionary Research. 2006;45(1):82-87. doi:10.1111/j.1439-0469.2006.00372.x' apa: 'Moder, K., Schlick Steiner, B., Steiner, F., Cremer, S., Christian, E., & Seifert, B. (2006). Optimal species distinction by discriminant analysis: comparing established methods of character selection with a combination procedure using ant morphometrics as a case study. Journal of Zoological Systematics and Evolutionary Research. Wiley-Blackwell. https://doi.org/10.1111/j.1439-0469.2006.00372.x' chicago: 'Moder, Karl, Birgit Schlick Steiner, Florian Steiner, Sylvia Cremer, Erhard Christian, and Bernhard Seifert. “Optimal Species Distinction by Discriminant Analysis: Comparing Established Methods of Character Selection with a Combination Procedure Using Ant Morphometrics as a Case Study.” Journal of Zoological Systematics and Evolutionary Research. Wiley-Blackwell, 2006. https://doi.org/10.1111/j.1439-0469.2006.00372.x.' ieee: 'K. Moder, B. Schlick Steiner, F. Steiner, S. Cremer, E. Christian, and B. Seifert, “Optimal species distinction by discriminant analysis: comparing established methods of character selection with a combination procedure using ant morphometrics as a case study,” Journal of Zoological Systematics and Evolutionary Research, vol. 45, no. 1. Wiley-Blackwell, pp. 82–87, 2006.' ista: 'Moder K, Schlick Steiner B, Steiner F, Cremer S, Christian E, Seifert B. 2006. Optimal species distinction by discriminant analysis: comparing established methods of character selection with a combination procedure using ant morphometrics as a case study. Journal of Zoological Systematics and Evolutionary Research. 45(1), 82–87.' mla: 'Moder, Karl, et al. “Optimal Species Distinction by Discriminant Analysis: Comparing Established Methods of Character Selection with a Combination Procedure Using Ant Morphometrics as a Case Study.” Journal of Zoological Systematics and Evolutionary Research, vol. 45, no. 1, Wiley-Blackwell, 2006, pp. 82–87, doi:10.1111/j.1439-0469.2006.00372.x.' short: K. Moder, B. Schlick Steiner, F. Steiner, S. Cremer, E. Christian, B. Seifert, Journal of Zoological Systematics and Evolutionary Research 45 (2006) 82–87. date_created: 2018-12-11T12:05:52Z date_published: 2006-08-29T00:00:00Z date_updated: 2021-01-12T07:53:10Z day: '29' doi: 10.1111/j.1439-0469.2006.00372.x extern: '1' intvolume: ' 45' issue: '1' language: - iso: eng month: '08' oa_version: None page: 82 - 87 publication: Journal of Zoological Systematics and Evolutionary Research publication_status: published publisher: Wiley-Blackwell publist_id: '2241' status: public title: 'Optimal species distinction by discriminant analysis: comparing established methods of character selection with a combination procedure using ant morphometrics as a case study' type: journal_article user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87 volume: 45 year: '2006' ... --- _id: '3913' abstract: - lang: eng text: Many invasive ant species, such as the Argentine ant or the red imported fire ant, have huge colonies with thousands of mass-foraging workers, which quickly monopolise resources and therefore represent a considerable threat to the native ant fauna. Cardiocondyla obscurior and several other species of this myrmicine genus have similarly been transferred throughout the tropics by human activities. However, because their colonies are tiny and workers forage solitarily, Cardiocondyla are often not recognized as successful invaders. Here, we document that the life history of Cardiocondyla closely resembles that of the more conspicuous tramp species, with polygyny, intranidal mating, budding, worker sterility, low genetic variability, and possibly also unicoloniality. Given that introduced Cardiocondyla may locally reach a very high population density, the effects of these stealthy invaders on the native arthropod fauna should receive more attention. author: - first_name: Jürgen full_name: Heinze, Jürgen last_name: Heinze - first_name: Sylvia full_name: Cremer, Sylvia id: 2F64EC8C-F248-11E8-B48F-1D18A9856A87 last_name: Cremer orcid: 0000-0002-2193-3868 - first_name: Norbert full_name: Eckl, Norbert last_name: Eckl - first_name: Alexandra full_name: Schrempf, Alexandra last_name: Schrempf citation: ama: 'Heinze J, Cremer S, Eckl N, Schrempf A. Stealthy invaders: the biology of Cardiocondyla tramp ants. Insectes Sociaux. 2006;53(1):1-7. doi:10.1007/s00040-005-0847-4' apa: 'Heinze, J., Cremer, S., Eckl, N., & Schrempf, A. (2006). Stealthy invaders: the biology of Cardiocondyla tramp ants. Insectes Sociaux. Springer. https://doi.org/10.1007/s00040-005-0847-4' chicago: 'Heinze, Jürgen, Sylvia Cremer, Norbert Eckl, and Alexandra Schrempf. “Stealthy Invaders: The Biology of Cardiocondyla Tramp Ants.” Insectes Sociaux. Springer, 2006. https://doi.org/10.1007/s00040-005-0847-4.' ieee: 'J. Heinze, S. Cremer, N. Eckl, and A. Schrempf, “Stealthy invaders: the biology of Cardiocondyla tramp ants,” Insectes Sociaux, vol. 53, no. 1. Springer, pp. 1–7, 2006.' ista: 'Heinze J, Cremer S, Eckl N, Schrempf A. 2006. Stealthy invaders: the biology of Cardiocondyla tramp ants. Insectes Sociaux. 53(1), 1–7.' mla: 'Heinze, Jürgen, et al. “Stealthy Invaders: The Biology of Cardiocondyla Tramp Ants.” Insectes Sociaux, vol. 53, no. 1, Springer, 2006, pp. 1–7, doi:10.1007/s00040-005-0847-4.' short: J. Heinze, S. Cremer, N. Eckl, A. Schrempf, Insectes Sociaux 53 (2006) 1–7. date_created: 2018-12-11T12:05:51Z date_published: 2006-02-01T00:00:00Z date_updated: 2021-01-12T07:53:09Z day: '01' doi: 10.1007/s00040-005-0847-4 extern: '1' intvolume: ' 53' issue: '1' language: - iso: eng month: '02' oa_version: None page: 1 - 7 publication: Insectes Sociaux publication_status: published publisher: Springer publist_id: '2240' status: public title: 'Stealthy invaders: the biology of Cardiocondyla tramp ants' type: journal_article user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87 volume: 53 year: '2006' ... --- _id: '3932' abstract: - lang: eng text: 'OBJECTIVES: The EGFR is expressed in malignant ovarian tumor tissue, and tissue content of EGFR has been directly associated with poor prognosis in patients with ovarian cancer. The uPA system plays a role in pericellular proteolysis, cell migration, invasion, and is over-expressed in ovarian cancer. This study explored the effects of EGF on uPAR expression in the ovarian cancer cell line OVCAR-3. METHODS: We used OVCAR-3 cells and the following methods: cell migration assay, time-lapse video microscopy, real-time PCR, assays for cellular binding of 125I-uPA and cellular degradation of 125I-uPA:PAI-1 complex, biosynthetic labeling using 35S-methionin, Western blot, Northern blot, and ELISAs for uPA, PAI-1, and uPAR. RESULTS: EGF up-regulates both protein and mRNA not only for uPAR, but also for the ligand uPA and its inhibitor PAI-1. Cell surface uPAR, in control as well as EGF-stimulated cells, is present only in the intact, not the cleaved, form. Ligand binding experiments showed an increase of endogenously occupied uPAR, whereas non-occupied receptor sites were not increased. In addition, EGF treatment resulted in decreased degradation of radiolabeled uPA:PAI-1 complex. This suggests decreased internalization of uPAR, since the complex is internalized together with uPAR. Like EGF, colchicine, which inhibits endocytosis, increased cell surface expression of uPAR. In addition, we found an immediate increase of uPAR after exposing the cells to EGF and this was accompanied by a transient increase of cell migration. The increase of cell surface uPAR in response to EGF is accompanied by increased release of the soluble form of uPAR (suPAR) to the medium as well as by increased cell migration. Both uPAR and suPAR increased in cells treated with the endocytosis inhibitor colchicine even though cell migration was inhibited, suggesting that the mechanism of uPAR shedding is not related to cell migration. CONCLUSION: Increased cell surface uPAR in response to EGF stimulation results from mobilization of uPAR from detergent-resistant domains, increased expression of uPAR mRNA, and decreased internalization and degradation of uPAR. Both the anti-uPAR antibody R3, which inhibits binding of uPA, and the EGFR phosphorylation inhibitor Iressa inhibited cell migration in response to uPA as well as to EGF, suggesting that EGFR and uPAR are engaged in the same multiprotein assembly on the cell surface.' author: - first_name: Emir full_name: Henic, Emir last_name: Henic - first_name: Michael K full_name: Michael Sixt id: 41E9FBEA-F248-11E8-B48F-1D18A9856A87 last_name: Sixt orcid: 0000-0002-6620-9179 - first_name: Stefan full_name: Hansson, Stefan last_name: Hansson - first_name: Gunilla full_name: Høyer-Hansen, Gunilla last_name: Høyer Hansen - first_name: Bertil full_name: Casslén, Bertil last_name: Casslén citation: ama: Henic E, Sixt MK, Hansson S, Høyer Hansen G, Casslén B. EGF-stimulated migration in ovarian cancer cells is associated with decreased internalization, increased surface expression, and increased shedding of the urokinase plasminogen activator receptor. Gynecologic Oncology. 2006;101(1):28-39. doi:10.1016/j.ygyno.2005.09.038 apa: Henic, E., Sixt, M. K., Hansson, S., Høyer Hansen, G., & Casslén, B. (2006). EGF-stimulated migration in ovarian cancer cells is associated with decreased internalization, increased surface expression, and increased shedding of the urokinase plasminogen activator receptor. Gynecologic Oncology. Elsevier. https://doi.org/10.1016/j.ygyno.2005.09.038 chicago: Henic, Emir, Michael K Sixt, Stefan Hansson, Gunilla Høyer Hansen, and Bertil Casslén. “EGF-Stimulated Migration in Ovarian Cancer Cells Is Associated with Decreased Internalization, Increased Surface Expression, and Increased Shedding of the Urokinase Plasminogen Activator Receptor.” Gynecologic Oncology. Elsevier, 2006. https://doi.org/10.1016/j.ygyno.2005.09.038. ieee: E. Henic, M. K. Sixt, S. Hansson, G. Høyer Hansen, and B. Casslén, “EGF-stimulated migration in ovarian cancer cells is associated with decreased internalization, increased surface expression, and increased shedding of the urokinase plasminogen activator receptor,” Gynecologic Oncology, vol. 101, no. 1. Elsevier, pp. 28–39, 2006. ista: Henic E, Sixt MK, Hansson S, Høyer Hansen G, Casslén B. 2006. EGF-stimulated migration in ovarian cancer cells is associated with decreased internalization, increased surface expression, and increased shedding of the urokinase plasminogen activator receptor. Gynecologic Oncology. 101(1), 28–39. mla: Henic, Emir, et al. “EGF-Stimulated Migration in Ovarian Cancer Cells Is Associated with Decreased Internalization, Increased Surface Expression, and Increased Shedding of the Urokinase Plasminogen Activator Receptor.” Gynecologic Oncology, vol. 101, no. 1, Elsevier, 2006, pp. 28–39, doi:10.1016/j.ygyno.2005.09.038. short: E. Henic, M.K. Sixt, S. Hansson, G. Høyer Hansen, B. Casslén, Gynecologic Oncology 101 (2006) 28–39. date_created: 2018-12-11T12:05:57Z date_published: 2006-04-01T00:00:00Z date_updated: 2021-01-12T07:53:17Z day: '01' doi: 10.1016/j.ygyno.2005.09.038 extern: 1 intvolume: ' 101' issue: '1' month: '04' page: 28 - 39 publication: Gynecologic Oncology publication_status: published publisher: Elsevier publist_id: '2194' quality_controlled: 0 status: public title: EGF-stimulated migration in ovarian cancer cells is associated with decreased internalization, increased surface expression, and increased shedding of the urokinase plasminogen activator receptor type: journal_article volume: 101 year: '2006' ... --- _id: '3978' abstract: - lang: eng text: Evaluating the quality of experimentally determined protein structural models is an essential step toward identifying potential errors and guiding further structural refinement. Herein, we report the use of proton local density as a sensitive measure to assess the quality of nuclear magnetic resonance (NMR) structures. Using 256 high-resolution crystal structures with protons added and optimized, we show that the local density of different proton types display distinct distributions. These distributions can be characterized by statistical moments and are used to establish local density Z-scores for evaluating both global and local packing for individual protons. Analysis of 546 crystal structures at various resolutions shows that the local density Z-scores increase as the structural resolution decreases and correlate well with the ClashScore (Word et al. J Mol Biol 1999;285(4):1711-1733) generated by all atom contact analysis. Local density Z-scores for NMR structures exhibit a significantly wider range of values than for X-ray structures and demonstrate a combination of potentially problematic inflation and compression. Water-refined NMR structures show improved packing quality. Our analysis of a high-quality structural ensemble of ubiquitin refined against order parameters shows proton density distributions that correlate nearly perfectly with our standards derived from crystal structures, further validating our approach. We present an automated analysis and visualization tool for proton packing to evaluate the quality of NMR structures. author: - first_name: Yih full_name: Ban, Yih-En Andrew last_name: Ban - first_name: Johannes full_name: Rudolph, Johannes last_name: Rudolph - first_name: Pei full_name: Zhou, Pei last_name: Zhou - first_name: Herbert full_name: Herbert Edelsbrunner id: 3FB178DA-F248-11E8-B48F-1D18A9856A87 last_name: Edelsbrunner orcid: 0000-0002-9823-6833 citation: ama: 'Ban Y, Rudolph J, Zhou P, Edelsbrunner H. Evaluating the quality of NMR structures by local density of protons. Proteins: Structure, Function and Bioinformatics. 2006;62(4):852-864. doi:10.1002/prot.20811' apa: 'Ban, Y., Rudolph, J., Zhou, P., & Edelsbrunner, H. (2006). Evaluating the quality of NMR structures by local density of protons. Proteins: Structure, Function and Bioinformatics. Wiley-Blackwell. https://doi.org/10.1002/prot.20811' chicago: 'Ban, Yih, Johannes Rudolph, Pei Zhou, and Herbert Edelsbrunner. “Evaluating the Quality of NMR Structures by Local Density of Protons.” Proteins: Structure, Function and Bioinformatics. Wiley-Blackwell, 2006. https://doi.org/10.1002/prot.20811.' ieee: 'Y. Ban, J. Rudolph, P. Zhou, and H. Edelsbrunner, “Evaluating the quality of NMR structures by local density of protons,” Proteins: Structure, Function and Bioinformatics, vol. 62, no. 4. Wiley-Blackwell, pp. 852–864, 2006.' ista: 'Ban Y, Rudolph J, Zhou P, Edelsbrunner H. 2006. Evaluating the quality of NMR structures by local density of protons. Proteins: Structure, Function and Bioinformatics. 62(4), 852–864.' mla: 'Ban, Yih, et al. “Evaluating the Quality of NMR Structures by Local Density of Protons.” Proteins: Structure, Function and Bioinformatics, vol. 62, no. 4, Wiley-Blackwell, 2006, pp. 852–64, doi:10.1002/prot.20811.' short: 'Y. Ban, J. Rudolph, P. Zhou, H. Edelsbrunner, Proteins: Structure, Function and Bioinformatics 62 (2006) 852–864.' date_created: 2018-12-11T12:06:14Z date_published: 2006-03-01T00:00:00Z date_updated: 2021-01-12T07:53:36Z day: '01' doi: 10.1002/prot.20811 extern: 1 intvolume: ' 62' issue: '4' month: '03' page: 852 - 864 publication: 'Proteins: Structure, Function and Bioinformatics' publication_status: published publisher: Wiley-Blackwell publist_id: '2146' quality_controlled: 0 status: public title: Evaluating the quality of NMR structures by local density of protons type: journal_article volume: 62 year: '2006' ... --- _id: '3979' abstract: - lang: eng text: Protein-protein interactions, which form the basis for most cellular processes, result in the formation of protein interfaces. Believing that the local shape of proteins is crucial, we take a geometric approach and present a definition of an interface surface formed by two or more proteins as a subset of their Voronoi diagram. The definition deals with the difficult and important problem of specifying interface boundaries by invoking methods used in the alpha shape representation of molecules, the discrete flow on Delaunay simplices to define pockets and reconstruct surfaces, and the assessment of the importance of topological features. We present an algorithm to construct the surface and define a hierarchy that distinguishes core and peripheral regions. This hierarchy is shown to have correlation with hot-spots in protein-protein interactions. Finally, we study the geometric and topological properties of interface surfaces and show their high degree of contortion. author: - first_name: Yih full_name: Ban, Yih-En Andrew last_name: Ban - first_name: Herbert full_name: Herbert Edelsbrunner id: 3FB178DA-F248-11E8-B48F-1D18A9856A87 last_name: Edelsbrunner orcid: 0000-0002-9823-6833 - first_name: Johannes full_name: Rudolph, Johannes last_name: Rudolph citation: ama: Ban Y, Edelsbrunner H, Rudolph J. Interface surfaces for protein-protein complexes. Journal of the ACM. 2006;53(3):361-378. doi:10.1145/1147954.1147957 apa: Ban, Y., Edelsbrunner, H., & Rudolph, J. (2006). Interface surfaces for protein-protein complexes. Journal of the ACM. ACM. https://doi.org/10.1145/1147954.1147957 chicago: Ban, Yih, Herbert Edelsbrunner, and Johannes Rudolph. “Interface Surfaces for Protein-Protein Complexes.” Journal of the ACM. ACM, 2006. https://doi.org/10.1145/1147954.1147957. ieee: Y. Ban, H. Edelsbrunner, and J. Rudolph, “Interface surfaces for protein-protein complexes,” Journal of the ACM, vol. 53, no. 3. ACM, pp. 361–378, 2006. ista: Ban Y, Edelsbrunner H, Rudolph J. 2006. Interface surfaces for protein-protein complexes. Journal of the ACM. 53(3), 361–378. mla: Ban, Yih, et al. “Interface Surfaces for Protein-Protein Complexes.” Journal of the ACM, vol. 53, no. 3, ACM, 2006, pp. 361–78, doi:10.1145/1147954.1147957. short: Y. Ban, H. Edelsbrunner, J. Rudolph, Journal of the ACM 53 (2006) 361–378. date_created: 2018-12-11T12:06:14Z date_published: 2006-05-01T00:00:00Z date_updated: 2021-01-12T07:53:37Z day: '01' doi: 10.1145/1147954.1147957 extern: 1 intvolume: ' 53' issue: '3' month: '05' page: 361 - 378 publication: Journal of the ACM publication_status: published publisher: ACM publist_id: '2147' quality_controlled: 0 status: public title: Interface surfaces for protein-protein complexes type: journal_article volume: 53 year: '2006' ... --- _id: '3980' abstract: - lang: eng text: Given a smoothly embedded 2-manifold in R-3, we define the elevation of a point as the height difference to a canonically defined second point on the same manifold. Our definition is invariant under rigid motions and can be used to define features such as lines of discontinuous or continuous but non-smooth elevation. We give an algorithm for finding points of locally maximum elevation, which we suggest mark cavities and protrusions and are useful in matching shapes as for example in protein docking. author: - first_name: Pankaj full_name: Agarwal, Pankaj K last_name: Agarwal - first_name: Herbert full_name: Herbert Edelsbrunner id: 3FB178DA-F248-11E8-B48F-1D18A9856A87 last_name: Edelsbrunner orcid: 0000-0002-9823-6833 - first_name: John full_name: Harer, John last_name: Harer - first_name: Yusu full_name: Wang, Yusu last_name: Wang citation: ama: Agarwal P, Edelsbrunner H, Harer J, Wang Y. Extreme elevation on a 2-manifold. Discrete & Computational Geometry. 2006;36(4):553-572. doi:10.1007/s00454-006-1265-8 apa: Agarwal, P., Edelsbrunner, H., Harer, J., & Wang, Y. (2006). Extreme elevation on a 2-manifold. Discrete & Computational Geometry. Springer. https://doi.org/10.1007/s00454-006-1265-8 chicago: Agarwal, Pankaj, Herbert Edelsbrunner, John Harer, and Yusu Wang. “Extreme Elevation on a 2-Manifold.” Discrete & Computational Geometry. Springer, 2006. https://doi.org/10.1007/s00454-006-1265-8. ieee: P. Agarwal, H. Edelsbrunner, J. Harer, and Y. Wang, “Extreme elevation on a 2-manifold,” Discrete & Computational Geometry, vol. 36, no. 4. Springer, pp. 553–572, 2006. ista: Agarwal P, Edelsbrunner H, Harer J, Wang Y. 2006. Extreme elevation on a 2-manifold. Discrete & Computational Geometry. 36(4), 553–572. mla: Agarwal, Pankaj, et al. “Extreme Elevation on a 2-Manifold.” Discrete & Computational Geometry, vol. 36, no. 4, Springer, 2006, pp. 553–72, doi:10.1007/s00454-006-1265-8. short: P. Agarwal, H. Edelsbrunner, J. Harer, Y. Wang, Discrete & Computational Geometry 36 (2006) 553–572. date_created: 2018-12-11T12:06:15Z date_published: 2006-12-01T00:00:00Z date_updated: 2021-01-12T07:53:38Z day: '01' doi: 10.1007/s00454-006-1265-8 extern: 1 intvolume: ' 36' issue: '4' month: '12' page: 553 - 572 publication: Discrete & Computational Geometry publication_status: published publisher: Springer publist_id: '2148' quality_controlled: 0 status: public title: Extreme elevation on a 2-manifold type: journal_article volume: 36 year: '2006' ... --- _id: '4345' abstract: - lang: eng text: Der Artikel beschäftigt sich mit dem Konzept der Bibliothek 2.0 (bzw. Library 2.0). Er skizziert anhand einiger Beispiele die Entwicklung zum Web 2.0 und beschreibt, wie Web 2.0-Technologien und -Anwendungen in Bibliotheken eingesetzt werden. Im Mittelpunkt stehen Social-Tagging-Systeme, benutzerorientierte Erweiterungen von Bibliothekskatalogen und Dokumentenservern sowie der Einsatz von Weblogs an Bibliotheken. Ferner werden neue Anforderungen an Bibliothekare diskutiert. author: - first_name: Patrick full_name: Patrick Danowski id: 2EBD1598-F248-11E8-B48F-1D18A9856A87 last_name: Danowski orcid: 0000-0002-6026-4409 - first_name: Lambert full_name: Heller,Lambert last_name: Heller citation: ama: Danowski P, Heller L. Bibliothek 2.0 - Die Bibliothek der Zukunft? Bibliotheksdienst. 2006;40(11):1250-1271. doi:424 apa: Danowski, P., & Heller, L. (2006). Bibliothek 2.0 - Die Bibliothek der Zukunft? Bibliotheksdienst. Zentral- und Landesbibliothek Berlin. https://doi.org/424 chicago: Danowski, Patrick, and Lambert Heller. “Bibliothek 2.0 - Die Bibliothek Der Zukunft?” Bibliotheksdienst. Zentral- und Landesbibliothek Berlin, 2006. https://doi.org/424. ieee: P. Danowski and L. Heller, “Bibliothek 2.0 - Die Bibliothek der Zukunft?,” Bibliotheksdienst, vol. 40, no. 11. Zentral- und Landesbibliothek Berlin, pp. 1250–1271, 2006. ista: Danowski P, Heller L. 2006. Bibliothek 2.0 - Die Bibliothek der Zukunft? Bibliotheksdienst. 40(11), 1250–1271. mla: Danowski, Patrick, and Lambert Heller. “Bibliothek 2.0 - Die Bibliothek Der Zukunft?” Bibliotheksdienst, vol. 40, no. 11, Zentral- und Landesbibliothek Berlin, 2006, pp. 1250–71, doi:424. short: P. Danowski, L. Heller, Bibliotheksdienst 40 (2006) 1250–1271. date_created: 2018-12-11T12:08:23Z date_published: 2006-01-01T00:00:00Z date_updated: 2021-01-12T07:56:17Z day: '01' doi: '424' extern: 1 intvolume: ' 40' issue: '11' main_file_link: - open_access: '0' url: http://www.zlb.de/aktivitaeten/bd_neu/heftinhalte2006/DigitaleBib011106.pdf month: '01' page: 1250 - 1271 publication: Bibliotheksdienst publication_status: published publisher: Zentral- und Landesbibliothek Berlin publist_id: '1229' quality_controlled: 0 status: public title: Bibliothek 2.0 - Die Bibliothek der Zukunft? type: journal_article volume: 40 year: '2006' ... --- _id: '4352' abstract: - lang: eng text: 'Anopheles darlingi is the primary malaria vector in Latin America, and is especially important in Amazonian Brazil. Historically, control efforts have been focused on indoor house spraying using a variety of insecticides, but since the mid-1990s there has been a shift to patient treatment and focal insecticide fogging. Anopheles darlingi was believed to have been significantly reduced in a gold-mining community, Peixoto de Azevedo (in Mato Grosso State), in the early 1990s by insecticide use during a severe malaria epidemic. In contrast, although An. darlingi was eradicated from some districts of the city of Belem (the capital of Para State) in 1968 to reduce malaria, populations around the water protection area in the eastern district were treated only briefly. To investigate the population structure of An. darlingi including evidence for a population bottleneck in Peixoto, we analyzed eight microsatellite loci of 256 individuals from seven locations in Brazil: three in Amapa State, three in Para State, and one in Mato Grosso State. Allelic diversity and mean expected heterozygosity were high for all populations (mean number alleles/locus and H(E) were 13.5 and 0.834, respectively) and did not differ significantly between locations. Significant heterozygote deficits were associated with linkage disequilibrium, most likely due to either the Wahlund effect or selection. We found no evidence for a population bottleneck in Peixoto, possibly because the reduction was not extreme enough to be detected. Overall estimates of long-term N(e) varied from 92.4 individuals under the linkage disequilibrium model to infinity under the heterozygote excess model. Fixation indices and analysis of molecular variance demonstrated significant differentiation between locations north and south of the Amazon River, suggesting a degree of genetic isolation between them, attributed to isolation by distance.' author: - first_name: Jan full_name: Conn, Jan E last_name: Conn - first_name: Joseph full_name: Vineis, Joseph H last_name: Vineis - first_name: Jonathan P full_name: Jonathan Bollback id: 2C6FA9CC-F248-11E8-B48F-1D18A9856A87 last_name: Bollback orcid: 0000-0002-4624-4612 - first_name: David full_name: Onyabe, David Y last_name: Onyabe - first_name: Richard full_name: Wilkerson, Richard C last_name: Wilkerson - first_name: Marinete full_name: Povoa, Marinete M last_name: Povoa citation: ama: Conn J, Vineis J, Bollback JP, Onyabe D, Wilkerson R, Povoa M. Population structure of the malaria vector Anopheles darlingi in a malaria-endemic region of eastern Amazonian Brazil. The American Journal of Tropical Medicine and Hygiene. 2006;74(5):798-806. apa: Conn, J., Vineis, J., Bollback, J. P., Onyabe, D., Wilkerson, R., & Povoa, M. (2006). Population structure of the malaria vector Anopheles darlingi in a malaria-endemic region of eastern Amazonian Brazil. The American Journal of Tropical Medicine and Hygiene. American Society of Tropical Medicine and Hygiene. chicago: Conn, Jan, Joseph Vineis, Jonathan P Bollback, David Onyabe, Richard Wilkerson, and Marinete Povoa. “Population Structure of the Malaria Vector Anopheles Darlingi in a Malaria-Endemic Region of Eastern Amazonian Brazil.” The American Journal of Tropical Medicine and Hygiene. American Society of Tropical Medicine and Hygiene, 2006. ieee: J. Conn, J. Vineis, J. P. Bollback, D. Onyabe, R. Wilkerson, and M. Povoa, “Population structure of the malaria vector Anopheles darlingi in a malaria-endemic region of eastern Amazonian Brazil,” The American Journal of Tropical Medicine and Hygiene, vol. 74, no. 5. American Society of Tropical Medicine and Hygiene, pp. 798–806, 2006. ista: Conn J, Vineis J, Bollback JP, Onyabe D, Wilkerson R, Povoa M. 2006. Population structure of the malaria vector Anopheles darlingi in a malaria-endemic region of eastern Amazonian Brazil. The American Journal of Tropical Medicine and Hygiene. 74(5), 798–806. mla: Conn, Jan, et al. “Population Structure of the Malaria Vector Anopheles Darlingi in a Malaria-Endemic Region of Eastern Amazonian Brazil.” The American Journal of Tropical Medicine and Hygiene, vol. 74, no. 5, American Society of Tropical Medicine and Hygiene, 2006, pp. 798–806. short: J. Conn, J. Vineis, J.P. Bollback, D. Onyabe, R. Wilkerson, M. Povoa, The American Journal of Tropical Medicine and Hygiene 74 (2006) 798–806. date_created: 2018-12-11T12:08:25Z date_published: 2006-05-01T00:00:00Z date_updated: 2021-01-12T07:56:20Z day: '01' extern: 1 intvolume: ' 74' issue: '5' main_file_link: - open_access: '0' url: http://www.ajtmh.org/content/74/5/798.full month: '05' page: 798 - 806 publication: The American Journal of Tropical Medicine and Hygiene publication_status: published publisher: American Society of Tropical Medicine and Hygiene publist_id: '1108' quality_controlled: 0 status: public title: Population structure of the malaria vector Anopheles darlingi in a malaria-endemic region of eastern Amazonian Brazil type: journal_article volume: 74 year: '2006' ... --- _id: '4351' abstract: - lang: eng text: 'BACKGROUND: Character mapping on phylogenies has played an important, if not critical role, in our understanding of molecular, morphological, and behavioral evolution. Until very recently we have relied on parsimony to infer character changes. Parsimony has a number of serious limitations that are drawbacks to our understanding. Recent statistical methods have been developed that free us from these limitations enabling us to overcome the problems of parsimony by accommodating uncertainty in evolutionary time, ancestral states, and the phylogeny. RESULTS: SIMMAP has been developed to implement stochastic character mapping that is useful to both molecular evolutionists, systematists, and bioinformaticians. Researchers can address questions about positive selection, patterns of amino acid substitution, character association, and patterns of morphological evolution. CONCLUSION: Stochastic character mapping, as implemented in the SIMMAP software, enables users to address questions that require mapping characters onto phylogenies using a probabilistic approach that does not rely on parsimony. Analyses can be performed using a fully Bayesian approach that is not reliant on considering a single topology, set of substitution model parameters, or reconstruction of ancestral states. Uncertainty in these quantities is accommodated by using MCMC samples from their respective posterior distributions.' author: - first_name: Jonathan P full_name: Jonathan Bollback id: 2C6FA9CC-F248-11E8-B48F-1D18A9856A87 last_name: Bollback orcid: 0000-0002-4624-4612 citation: ama: 'Bollback JP. SIMMAP: stochastic character mapping of discrete traits on phylogenies. BMC Bioinformatics. 2006;7. doi:10.1186/1471-2105-7-88' apa: 'Bollback, J. P. (2006). SIMMAP: stochastic character mapping of discrete traits on phylogenies. BMC Bioinformatics. BioMed Central. https://doi.org/10.1186/1471-2105-7-88' chicago: 'Bollback, Jonathan P. “SIMMAP: Stochastic Character Mapping of Discrete Traits on Phylogenies.” BMC Bioinformatics. BioMed Central, 2006. https://doi.org/10.1186/1471-2105-7-88.' ieee: 'J. P. Bollback, “SIMMAP: stochastic character mapping of discrete traits on phylogenies,” BMC Bioinformatics, vol. 7. BioMed Central, 2006.' ista: 'Bollback JP. 2006. SIMMAP: stochastic character mapping of discrete traits on phylogenies. BMC Bioinformatics. 7.' mla: 'Bollback, Jonathan P. “SIMMAP: Stochastic Character Mapping of Discrete Traits on Phylogenies.” BMC Bioinformatics, vol. 7, BioMed Central, 2006, doi:10.1186/1471-2105-7-88.' short: J.P. Bollback, BMC Bioinformatics 7 (2006). date_created: 2018-12-11T12:08:25Z date_published: 2006-01-01T00:00:00Z date_updated: 2021-01-12T07:56:20Z day: '01' doi: 10.1186/1471-2105-7-88 extern: 1 intvolume: ' 7' license: https://creativecommons.org/licenses/by/4.0/ month: '01' publication: BMC Bioinformatics publication_status: published publisher: BioMed Central publist_id: '1109' quality_controlled: 0 status: public title: 'SIMMAP: stochastic character mapping of discrete traits on phylogenies' tmp: image: /images/cc_by.png legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0) short: CC BY (4.0) type: journal_article volume: 7 year: '2006' ... --- _id: '3180' abstract: - lang: eng text: 'One of the most exciting advances in early vision has been the development of efficient energy minimization algorithms. Many early vision tasks require labeling each pixel with some quantity such as depth or texture. While many such problems can be elegantly expressed in the language of Markov Random Fields (MRF''s), the resulting energy minimization problems were widely viewed as intractable. Recently, algorithms such as graph cuts and loopy belief propagation (LBP) have proven to be very powerful: for example, such methods form the basis for almost all the top-performing stereo methods. Unfortunately, most papers define their own energy function, which is minimized with a specific algorithm of their choice. As a result, the tradeoffs among different energy minimization algorithms are not well understood. In this paper we describe a set of energy minimization benchmarks, which we use to compare the solution quality and running time of several common energy minimization algorithms. We investigate three promising recent methods - graph cuts, LBP, and tree-reweighted message passing - as well as the well-known older iterated conditional modes (ICM) algorithm. Our benchmark problems are drawn from published energy functions used for stereo, image stitching and interactive segmentation. We also provide a general-purpose software interface that allows vision researchers to easily switch between optimization methods with minimal overhead. We expect that the availability of our benchmarks and interface will make it significantly easier for vision researchers to adopt the best method for their specific problems. Benchmarks, code, results and images are available at http://vision.middlebury.edu/MRF.' author: - first_name: Richard full_name: Szeliski, Richard S last_name: Szeliski - first_name: Ramin full_name: Zabih, Ramin last_name: Zabih - first_name: Daniel full_name: Scharstein, Daniel last_name: Scharstein - first_name: Olga full_name: Veksler, Olga last_name: Veksler - first_name: Vladimir full_name: Vladimir Kolmogorov id: 3D50B0BA-F248-11E8-B48F-1D18A9856A87 last_name: Kolmogorov - first_name: Aseem full_name: Agarwala, Aseem last_name: Agarwala - first_name: Marshall full_name: Tappen, Marshall F last_name: Tappen - first_name: Carsten full_name: Rother, Carsten last_name: Rother citation: ama: 'Szeliski R, Zabih R, Scharstein D, et al. A comparative study of energy minimization methods for Markov random fields. In: Vol 3952. Springer; 2006:16-29. doi:10.1007/11744047_2' apa: 'Szeliski, R., Zabih, R., Scharstein, D., Veksler, O., Kolmogorov, V., Agarwala, A., … Rother, C. (2006). A comparative study of energy minimization methods for Markov random fields (Vol. 3952, pp. 16–29). Presented at the ECCV: European Conference on Computer Vision, Springer. https://doi.org/10.1007/11744047_2' chicago: Szeliski, Richard, Ramin Zabih, Daniel Scharstein, Olga Veksler, Vladimir Kolmogorov, Aseem Agarwala, Marshall Tappen, and Carsten Rother. “A Comparative Study of Energy Minimization Methods for Markov Random Fields,” 3952:16–29. Springer, 2006. https://doi.org/10.1007/11744047_2. ieee: 'R. Szeliski et al., “A comparative study of energy minimization methods for Markov random fields,” presented at the ECCV: European Conference on Computer Vision, 2006, vol. 3952, pp. 16–29.' ista: 'Szeliski R, Zabih R, Scharstein D, Veksler O, Kolmogorov V, Agarwala A, Tappen M, Rother C. 2006. A comparative study of energy minimization methods for Markov random fields. ECCV: European Conference on Computer Vision vol. 3952, 16–29.' mla: Szeliski, Richard, et al. A Comparative Study of Energy Minimization Methods for Markov Random Fields. Vol. 3952, Springer, 2006, pp. 16–29, doi:10.1007/11744047_2. short: R. Szeliski, R. Zabih, D. Scharstein, O. Veksler, V. Kolmogorov, A. Agarwala, M. Tappen, C. Rother, in:, Springer, 2006, pp. 16–29. conference: name: 'ECCV: European Conference on Computer Vision' date_created: 2018-12-11T12:01:51Z date_published: 2006-05-03T00:00:00Z date_updated: 2021-01-12T07:41:37Z day: '03' doi: 10.1007/11744047_2 extern: 1 intvolume: ' 3952' main_file_link: - open_access: '0' url: http://research-srv.microsoft.com/pubs/67896/szsvkatr-eccv06.pdf month: '05' page: 16 - 29 publication_status: published publisher: Springer publist_id: '3499' quality_controlled: 0 status: public title: A comparative study of energy minimization methods for Markov random fields type: conference volume: 3952 year: '2006' ...