---
_id: '3584'
abstract:
- lang: eng
text: We develop fast algorithms for computing the linking number of a simplicial
complex within a filtration.We give experimental results in applying our work
toward the detection of non-trivial tangling in biomolecules, modeled as alpha
complexes.
author:
- first_name: Herbert
full_name: Edelsbrunner, Herbert
id: 3FB178DA-F248-11E8-B48F-1D18A9856A87
last_name: Edelsbrunner
orcid: 0000-0002-9823-6833
- first_name: Afra
full_name: Zomorodian, Afra
last_name: Zomorodian
citation:
ama: Edelsbrunner H, Zomorodian A. Computing linking numbers of a filtration. Homology,
Homotopy and Applications. 2003;5(2):19-37.
apa: Edelsbrunner, H., & Zomorodian, A. (2003). Computing linking numbers of
a filtration. Homology, Homotopy and Applications. International Press.
chicago: Edelsbrunner, Herbert, and Afra Zomorodian. “Computing Linking Numbers
of a Filtration.” Homology, Homotopy and Applications. International Press,
2003.
ieee: H. Edelsbrunner and A. Zomorodian, “Computing linking numbers of a filtration,”
Homology, Homotopy and Applications, vol. 5, no. 2. International Press,
pp. 19–37, 2003.
ista: Edelsbrunner H, Zomorodian A. 2003. Computing linking numbers of a filtration.
Homology, Homotopy and Applications. 5(2), 19–37.
mla: Edelsbrunner, Herbert, and Afra Zomorodian. “Computing Linking Numbers of a
Filtration.” Homology, Homotopy and Applications, vol. 5, no. 2, International
Press, 2003, pp. 19–37.
short: H. Edelsbrunner, A. Zomorodian, Homology, Homotopy and Applications 5 (2003)
19–37.
date_created: 2018-12-11T12:04:05Z
date_published: 2003-04-22T00:00:00Z
date_updated: 2021-01-12T07:44:28Z
day: '22'
extern: '1'
intvolume: ' 5'
issue: '2'
language:
- iso: eng
main_file_link:
- url: http://projecteuclid.org/euclid.hha/1088453320
month: '04'
oa_version: None
page: 19 - 37
publication: Homology, Homotopy and Applications
publication_status: published
publisher: International Press
publist_id: '2801'
quality_controlled: '1'
status: public
title: Computing linking numbers of a filtration
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 5
year: '2003'
...
---
_id: '3620'
abstract:
- lang: eng
text: 'Stable hybrid zones in which ecologically divergent taxa give rise to a range
of recombinants are natural laboratories in which the genetic basis of adaptation
and reproductive isolation can be unraveled. One such hybrid zone is formed by
the fire-bellied toads Bombina bombina and B. variegata (Anura: Discoglossidae).
Adaptations to permanent and ephemeral breeding habitats, respectively, have shaped
numerous phenotypic differences between the taxa. All of these are, in principle,
candidates for a genetic dissection via QTL mapping. We present here a linkage
map of 28 codominant and 10 dominant markers in the Bombina genome. In an F2 cross,
markers that were mainly microsatellites, SSCPs or allozymes were mapped to 20
linkage groups. Among the 40 isolated CA microsatellites, we noted a preponderance
of compound and frequently interleaved CA-TA repeats as well as a striking polarity
at the 5′ end of the repeats.'
author:
- first_name: Beate
full_name: Nürnberger, Beate
last_name: Nürnberger
- first_name: Sebastian
full_name: Hofman, Sebastian
last_name: Hofman
- first_name: Bqruni
full_name: Förg-Brey, Bqruni
last_name: Förg Brey
- first_name: Gabriele
full_name: Praetzel, Gabriele
last_name: Praetzel
- first_name: Alan
full_name: Maclean, Alan W
last_name: Maclean
- first_name: Jacek
full_name: Szymura, Jacek M
last_name: Szymura
- first_name: Catherine
full_name: Abbott, Catherine M
last_name: Abbott
- first_name: Nicholas H
full_name: Nicholas Barton
id: 4880FE40-F248-11E8-B48F-1D18A9856A87
last_name: Barton
orcid: 0000-0002-8548-5240
citation:
ama: 'Nürnberger B, Hofman S, Förg Brey B, et al. A linkage map for the hybridising
toads Bombina bombina and B. variegata (Anura: Discoglossidae). Heredity.
2003;91(2):136-142. doi:10.1038/sj.hdy.6800291'
apa: 'Nürnberger, B., Hofman, S., Förg Brey, B., Praetzel, G., Maclean, A., Szymura,
J., … Barton, N. H. (2003). A linkage map for the hybridising toads Bombina bombina
and B. variegata (Anura: Discoglossidae). Heredity. Nature Publishing Group.
https://doi.org/10.1038/sj.hdy.6800291'
chicago: 'Nürnberger, Beate, Sebastian Hofman, Bqruni Förg Brey, Gabriele Praetzel,
Alan Maclean, Jacek Szymura, Catherine Abbott, and Nicholas H Barton. “A Linkage
Map for the Hybridising Toads Bombina Bombina and B. Variegata (Anura: Discoglossidae).”
Heredity. Nature Publishing Group, 2003. https://doi.org/10.1038/sj.hdy.6800291.'
ieee: 'B. Nürnberger et al., “A linkage map for the hybridising toads Bombina
bombina and B. variegata (Anura: Discoglossidae),” Heredity, vol. 91, no.
2. Nature Publishing Group, pp. 136–142, 2003.'
ista: 'Nürnberger B, Hofman S, Förg Brey B, Praetzel G, Maclean A, Szymura J, Abbott
C, Barton NH. 2003. A linkage map for the hybridising toads Bombina bombina and
B. variegata (Anura: Discoglossidae). Heredity. 91(2), 136–142.'
mla: 'Nürnberger, Beate, et al. “A Linkage Map for the Hybridising Toads Bombina
Bombina and B. Variegata (Anura: Discoglossidae).” Heredity, vol. 91, no.
2, Nature Publishing Group, 2003, pp. 136–42, doi:10.1038/sj.hdy.6800291.'
short: B. Nürnberger, S. Hofman, B. Förg Brey, G. Praetzel, A. Maclean, J. Szymura,
C. Abbott, N.H. Barton, Heredity 91 (2003) 136–142.
date_created: 2018-12-11T12:04:17Z
date_published: 2003-08-01T00:00:00Z
date_updated: 2021-01-12T07:44:43Z
day: '01'
doi: 10.1038/sj.hdy.6800291
extern: 1
intvolume: ' 91'
issue: '2'
month: '08'
page: 136 - 142
publication: Heredity
publication_status: published
publisher: Nature Publishing Group
publist_id: '2763'
quality_controlled: 0
status: public
title: 'A linkage map for the hybridising toads Bombina bombina and B. variegata (Anura:
Discoglossidae)'
type: journal_article
volume: 91
year: '2003'
...
---
_id: '3619'
abstract:
- lang: eng
text: What is the chance that some part of a stretch of genome will survive? In
a population of constant size, and with no selection, the probability of survival
of some part of a stretch of map length y<1 approaches View the MathML source
for View the MathML source. Thus, the whole genome is certain to be lost, but
the rate of loss is extremely slow. This solution extends to give the whole distribution
of surviving block sizes as a function of time. We show that the expected number
of blocks at time t is 1+yt and give expressions for the moments of the number
of blocks and the total amount of genome that survives for a given time. The solution
is based on a branching process and assumes complete interference between crossovers,
so that each descendant carries only a single block of ancestral material. We
consider cases where most individuals carry multiple blocks, either because there
are multiple crossovers in a long genetic map, or because enough time has passed
that most individuals in the population are related to each other. For species
such as ours, which have a long genetic map, the genome of any individual which
leaves descendants (∼80% of the population for a Poisson offspring number with
mean two) is likely to persist for an extremely long time, in the form of a few
short blocks of genome.
author:
- first_name: Stuart
full_name: Baird, Stuart J
last_name: Baird
- first_name: Nicholas H
full_name: Nicholas Barton
id: 4880FE40-F248-11E8-B48F-1D18A9856A87
last_name: Barton
orcid: 0000-0002-8548-5240
- first_name: Alison
full_name: Etheridge, Alison M
last_name: Etheridge
citation:
ama: Baird S, Barton NH, Etheridge A. The distribution of surviving blocks of an
ancestral genome. Theoretical Population Biology. 2003;64(4):451-471. doi:10.1016/S0040-5809(03)00098-4
apa: Baird, S., Barton, N. H., & Etheridge, A. (2003). The distribution of surviving
blocks of an ancestral genome. Theoretical Population Biology. Academic
Press. https://doi.org/10.1016/S0040-5809(03)00098-4
chicago: Baird, Stuart, Nicholas H Barton, and Alison Etheridge. “The Distribution
of Surviving Blocks of an Ancestral Genome.” Theoretical Population Biology.
Academic Press, 2003. https://doi.org/10.1016/S0040-5809(03)00098-4.
ieee: S. Baird, N. H. Barton, and A. Etheridge, “The distribution of surviving blocks
of an ancestral genome,” Theoretical Population Biology, vol. 64, no. 4.
Academic Press, pp. 451–471, 2003.
ista: Baird S, Barton NH, Etheridge A. 2003. The distribution of surviving blocks
of an ancestral genome. Theoretical Population Biology. 64(4), 451–471.
mla: Baird, Stuart, et al. “The Distribution of Surviving Blocks of an Ancestral
Genome.” Theoretical Population Biology, vol. 64, no. 4, Academic Press,
2003, pp. 451–71, doi:10.1016/S0040-5809(03)00098-4.
short: S. Baird, N.H. Barton, A. Etheridge, Theoretical Population Biology 64 (2003)
451–471.
date_created: 2018-12-11T12:04:17Z
date_published: 2003-12-01T00:00:00Z
date_updated: 2021-01-12T07:44:42Z
day: '01'
doi: 10.1016/S0040-5809(03)00098-4
extern: 1
intvolume: ' 64'
issue: '4'
month: '12'
page: 451 - 471
publication: Theoretical Population Biology
publication_status: published
publisher: Academic Press
publist_id: '2764'
quality_controlled: 0
status: public
title: The distribution of surviving blocks of an ancestral genome
type: journal_article
volume: 64
year: '2003'
...
---
_id: '3618'
abstract:
- lang: eng
text: There are several analyses in evolutionary ecology which assume that a family
of offspring has come from only two parents. Here, we present a simple test for
detecting when a batch involves two or more subfamilies. It is based on the fact
that the mixing of families generates associations amongst unlinked marker loci.
We also present simulations illustrating the power of our method for varying numbers
of loci, alleles per locus and genotyped individuals.
author:
- first_name: Timothy
full_name: Vines, Timothy H
last_name: Vines
- first_name: Nicholas H
full_name: Nicholas Barton
id: 4880FE40-F248-11E8-B48F-1D18A9856A87
last_name: Barton
orcid: 0000-0002-8548-5240
citation:
ama: Vines T, Barton NH. A new approach to detecting mixed families. Molecular
Ecology. 2003;12(7):1999-2002. doi:10.1046/j.1365-294X.2003.01867.x
apa: Vines, T., & Barton, N. H. (2003). A new approach to detecting mixed families.
Molecular Ecology. Wiley-Blackwell. https://doi.org/10.1046/j.1365-294X.2003.01867.x
chicago: Vines, Timothy, and Nicholas H Barton. “A New Approach to Detecting Mixed
Families.” Molecular Ecology. Wiley-Blackwell, 2003. https://doi.org/10.1046/j.1365-294X.2003.01867.x.
ieee: T. Vines and N. H. Barton, “A new approach to detecting mixed families,” Molecular
Ecology, vol. 12, no. 7. Wiley-Blackwell, pp. 1999–2002, 2003.
ista: Vines T, Barton NH. 2003. A new approach to detecting mixed families. Molecular
Ecology. 12(7), 1999–2002.
mla: Vines, Timothy, and Nicholas H. Barton. “A New Approach to Detecting Mixed
Families.” Molecular Ecology, vol. 12, no. 7, Wiley-Blackwell, 2003, pp.
1999–2002, doi:10.1046/j.1365-294X.2003.01867.x.
short: T. Vines, N.H. Barton, Molecular Ecology 12 (2003) 1999–2002.
date_created: 2018-12-11T12:04:16Z
date_published: 2003-07-01T00:00:00Z
date_updated: 2021-01-12T07:44:42Z
day: '01'
doi: 10.1046/j.1365-294X.2003.01867.x
extern: 1
intvolume: ' 12'
issue: '7'
month: '07'
page: 1999 - 2002
publication: Molecular Ecology
publication_status: published
publisher: Wiley-Blackwell
publist_id: '2765'
quality_controlled: 0
status: public
title: A new approach to detecting mixed families
type: journal_article
volume: 12
year: '2003'
...
---
_id: '3752'
abstract:
- lang: eng
text: We use the lac operon in Escherichia coli as a prototype system to illustrate
the current state, applicability, and limitations of modeling the dynamics of
cellular networks. We integrate three different levels of description (molecular,
cellular, and that of cell population) into a single model, which seems to capture
many experimental aspects of the system.
author:
- first_name: Jose
full_name: Vilar,Jose M
last_name: Vilar
- first_name: Calin C
full_name: Calin Guet
id: 47F8433E-F248-11E8-B48F-1D18A9856A87
last_name: Guet
orcid: 0000-0001-6220-2052
- first_name: Stanislas
full_name: Leibler, Stanislas
last_name: Leibler
citation:
ama: 'Vilar J, Guet CC, Leibler S. Modeling network dynamics: the lac operon, a
case study. Journal of Cell Biology. 2003;161(3):471-476. doi:10.1083/jcb.200301125'
apa: 'Vilar, J., Guet, C. C., & Leibler, S. (2003). Modeling network dynamics:
the lac operon, a case study. Journal of Cell Biology. Rockefeller University
Press. https://doi.org/10.1083/jcb.200301125'
chicago: 'Vilar, Jose, Calin C Guet, and Stanislas Leibler. “Modeling Network Dynamics:
The Lac Operon, a Case Study.” Journal of Cell Biology. Rockefeller University
Press, 2003. https://doi.org/10.1083/jcb.200301125.'
ieee: 'J. Vilar, C. C. Guet, and S. Leibler, “Modeling network dynamics: the lac
operon, a case study,” Journal of Cell Biology, vol. 161, no. 3. Rockefeller
University Press, pp. 471–476, 2003.'
ista: 'Vilar J, Guet CC, Leibler S. 2003. Modeling network dynamics: the lac operon,
a case study. Journal of Cell Biology. 161(3), 471–476.'
mla: 'Vilar, Jose, et al. “Modeling Network Dynamics: The Lac Operon, a Case Study.”
Journal of Cell Biology, vol. 161, no. 3, Rockefeller University Press,
2003, pp. 471–76, doi:10.1083/jcb.200301125.'
short: J. Vilar, C.C. Guet, S. Leibler, Journal of Cell Biology 161 (2003) 471–476.
date_created: 2018-12-11T12:04:58Z
date_published: 2003-01-12T00:00:00Z
date_updated: 2021-01-12T07:51:57Z
day: '12'
doi: 10.1083/jcb.200301125
extern: 1
intvolume: ' 161'
issue: '3'
main_file_link:
- open_access: '1'
url: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2172934/?tool=pubmed
month: '01'
oa: 1
page: 471 - 476
publication: Journal of Cell Biology
publication_status: published
publisher: Rockefeller University Press
publist_id: '2475'
quality_controlled: 0
status: public
title: 'Modeling network dynamics: the lac operon, a case study'
type: journal_article
volume: 161
year: '2003'
...