---
_id: '4350'
abstract:
- lang: eng
text: 'The phylogeny of Crocodylia offers an unusual twist on the usual molecules
versus morphology story. The true gharial (Gavialis gangeticus) and the false
gharial (Tomistoma schlegelii), as their common names imply, have appeared in
all cladistic morphological analyses as distantly related species, convergent
upon a similar morphology. In contrast, all previous molecular studies have shown
them to be sister taxa. We present the first phylogenetic study of Crocodylia
using a nuclear gene. We cloned and sequenced the c-myc proto-oncogene from Alligator
mississippiensis to facilitate primer design and then sequenced an 1,100-base
pair fragment that includes both coding and noncoding regions and informative
indels for one species in each extant crocodylian genus and six avian outgroups.
Phylogenetic analyses using parsimony, maximum likelihood, and Bayesian inference
all strongly agreed on the same tree, which is identical to the tree found in
previous molecular analyses: Gavialis and Tomistoma are sister taxa and together
are the sister group of Crocodylidae. Kishino-Hasegawa tests rejected the morphological
tree in favor of the molecular tree. We excluded long-branch attraction and variation
in base composition among taxa as explanations for this topology. To explore the
causes of discrepancy between molecular and morphological estimates of crocodylian
phylogeny, we examined puzzling features of the morphological data using a priori
partitions of the data based on anatomical regions and investigated the effects
of different coding schemes for two obvious morphological similarities of the
two gharials.'
acknowledgement: "We thank Lou Densmore and Herb Dessauer for crocodylian tissue\r\nsamples.
Dave Swofford, Jim Wilgenbusch, and Kevin de Queiroz gave\r\nus much helpful advice.
Dave also allowed us to use an experimental\r\nversion of PAUP∗ with partitioned
likelihood, and Jim also provided\r\nprograms to make possible partitioned model
KH tests. Chris Brochu\r\nand Lou Densmore sent us preprints of their papers in
press, and Chris\r\nprovided an unpublished version of his morphological data set.
Allan\r\nBaker, Lou Densmore, and an anonymous reviewer provided useful\r\ncomments
on the manuscript. We especially wish to acknowledge Chris\r\nBrochu’s help; although
we remain in disagreement on many points,\r\nhis comments on several previous drafts
have greatly improved this\r\npaper."
article_processing_charge: No
article_type: original
author:
- first_name: John
full_name: Harshman, John
last_name: Harshman
- first_name: Christopher
full_name: Huddleston, Christopher
last_name: Huddleston
- first_name: Jonathan P
full_name: Bollback, Jonathan P
id: 2C6FA9CC-F248-11E8-B48F-1D18A9856A87
last_name: Bollback
orcid: 0000-0002-4624-4612
- first_name: Thomas
full_name: Parsons, Thomas
last_name: Parsons
- first_name: Michael
full_name: Braun, Michael
last_name: Braun
citation:
ama: 'Harshman J, Huddleston C, Bollback JP, Parsons T, Braun M. True and false
gharials: A nuclear gene phylogeny of crocodylia. Systematic Biology. 2003;52(3):386-402.
doi:10.1080/10635150390197028'
apa: 'Harshman, J., Huddleston, C., Bollback, J. P., Parsons, T., & Braun, M.
(2003). True and false gharials: A nuclear gene phylogeny of crocodylia. Systematic
Biology. Oxford University Press. https://doi.org/10.1080/10635150390197028'
chicago: 'Harshman, John, Christopher Huddleston, Jonathan P Bollback, Thomas Parsons,
and Michael Braun. “True and False Gharials: A Nuclear Gene Phylogeny of Crocodylia.”
Systematic Biology. Oxford University Press, 2003. https://doi.org/10.1080/10635150390197028.'
ieee: 'J. Harshman, C. Huddleston, J. P. Bollback, T. Parsons, and M. Braun, “True
and false gharials: A nuclear gene phylogeny of crocodylia,” Systematic Biology,
vol. 52, no. 3. Oxford University Press, pp. 386–402, 2003.'
ista: 'Harshman J, Huddleston C, Bollback JP, Parsons T, Braun M. 2003. True and
false gharials: A nuclear gene phylogeny of crocodylia. Systematic Biology. 52(3),
386–402.'
mla: 'Harshman, John, et al. “True and False Gharials: A Nuclear Gene Phylogeny
of Crocodylia.” Systematic Biology, vol. 52, no. 3, Oxford University Press,
2003, pp. 386–402, doi:10.1080/10635150390197028.'
short: J. Harshman, C. Huddleston, J.P. Bollback, T. Parsons, M. Braun, Systematic
Biology 52 (2003) 386–402.
date_created: 2018-12-11T12:08:24Z
date_published: 2003-06-01T00:00:00Z
date_updated: 2024-01-23T08:53:58Z
day: '01'
doi: 10.1080/10635150390197028
extern: '1'
external_id:
pmid:
- ' 12775527'
intvolume: ' 52'
issue: '3'
language:
- iso: eng
month: '06'
oa_version: None
page: 386 - 402
pmid: 1
publication: Systematic Biology
publication_identifier:
issn:
- '0039-7989 '
publication_status: published
publisher: Oxford University Press
publist_id: '1110'
quality_controlled: '1'
scopus_import: '1'
status: public
title: 'True and false gharials: A nuclear gene phylogeny of crocodylia'
type: journal_article
user_id: ea97e931-d5af-11eb-85d4-e6957dddbf17
volume: 52
year: '2003'
...
---
_id: '4348'
abstract:
- lang: eng
text: Many questions in evolutionary biology are best addressed by comparing traits
in different species. Often such studies involve mapping characters on phylogenetic
trees. Mapping characters on trees allows the nature, number, and timing of the
transformations to be identified. The parsimony method is the only method available
for mapping morphological characters on phylogenies. Although the parsimony method
often makes reasonable reconstructions of the history of a character, it has a
number of limitations. These limitations include the inability to consider more
than a single change along a branch on a tree and the uncoupling of evolutionary
time from amount of character change. We extended a method described by Nielsen
(2002, Syst. Biol. 51:729-739) to the mapping of morphological characters under
continuous-time Markov models and demonstrate here the utility of the method for
mapping characters on trees and for identifying character correlation.
acknowledgement: "We thank J. Kohn, D. Stern, and M. Hart for sending the alignments\r\nused
in this study. J.P.H. was supported by NSF grants DEB-0075406\r\nand MCB-0075404.
R.N. was supported by NSF grant DEB-0089487."
article_processing_charge: No
article_type: original
author:
- first_name: John
full_name: Huelsenbeck, John
last_name: Huelsenbeck
- first_name: Rasmus
full_name: Nielsen, Rasmus
last_name: Nielsen
- first_name: Jonathan P
full_name: Bollback, Jonathan P
id: 2C6FA9CC-F248-11E8-B48F-1D18A9856A87
last_name: Bollback
orcid: 0000-0002-4624-4612
citation:
ama: Huelsenbeck J, Nielsen R, Bollback JP. Stochastic mapping of morphological
characters. Systematic Biology. 2003;52(2):131-158. doi:10.1080/10635150390192780
apa: Huelsenbeck, J., Nielsen, R., & Bollback, J. P. (2003). Stochastic mapping
of morphological characters. Systematic Biology. Oxford University Press.
https://doi.org/10.1080/10635150390192780
chicago: Huelsenbeck, John, Rasmus Nielsen, and Jonathan P Bollback. “Stochastic
Mapping of Morphological Characters.” Systematic Biology. Oxford University
Press, 2003. https://doi.org/10.1080/10635150390192780.
ieee: J. Huelsenbeck, R. Nielsen, and J. P. Bollback, “Stochastic mapping of morphological
characters,” Systematic Biology, vol. 52, no. 2. Oxford University Press,
pp. 131–158, 2003.
ista: Huelsenbeck J, Nielsen R, Bollback JP. 2003. Stochastic mapping of morphological
characters. Systematic Biology. 52(2), 131–158.
mla: Huelsenbeck, John, et al. “Stochastic Mapping of Morphological Characters.”
Systematic Biology, vol. 52, no. 2, Oxford University Press, 2003, pp.
131–58, doi:10.1080/10635150390192780.
short: J. Huelsenbeck, R. Nielsen, J.P. Bollback, Systematic Biology 52 (2003) 131–158.
date_created: 2018-12-11T12:08:24Z
date_published: 2003-04-01T00:00:00Z
date_updated: 2024-01-23T09:10:59Z
day: '01'
doi: 10.1080/10635150390192780
extern: '1'
external_id:
pmid:
- '12746144 '
intvolume: ' 52'
issue: '2'
language:
- iso: eng
month: '04'
oa_version: None
page: 131 - 158
pmid: 1
publication: Systematic Biology
publication_identifier:
issn:
- '0039-7989 '
publication_status: published
publisher: Oxford University Press
publist_id: '1111'
quality_controlled: '1'
scopus_import: '1'
status: public
title: Stochastic mapping of morphological characters
type: journal_article
user_id: ea97e931-d5af-11eb-85d4-e6957dddbf17
volume: 52
year: '2003'
...
---
_id: '4254'
abstract:
- lang: eng
text: Chromosomal rearrangements can promote reproductive isolation by reducing
recombination along a large section of the genome. We model the effects of the
genetic barrier to gene flow caused by a chromosomal rearrangement on the rate
of accumulation of postzygotic isolation genes in parapatry. We find that, if
reproductive isolation is produced by the accumulation in parapatry of sets of
alleles compatible within but incompatible across species, chromosomal rearrangements
are far more likely to favor it than classical genetic barriers without chromosomal
changes. New evidence of the role of chromosomal rearrangements in parapatric
speciation suggests that postzygotic isolation is often due to the accumulation
of such incompatibilities. The model makes testable qualitative predictions about
the genetic signature of speciation.
acknowledgement: "We thank A. Andrés, C. Bartolomé, J. Bertranpetit, F. Calafell,
B. Charlesworth, D. Charlesworth, F. Depaulis, S. Gavrilets, T. Johnson, P. Keightley,
M. Kirkpatrik, A. Kondrashov, H. Laayouni, X. Maside, M. Noor, D. Ortiz-Barrientos,\r\nL.
Rieseberg, and T. Vines for valuable discussion and criticism. The detailed comments
of B. Charlesworth, D. Charlesworth, and F. Depaulis greatly improved the original
manuscript. AN is particularly grateful to X. Maside, who was a patient guide through
the jungle of speciation. This work was supported by the NERC grant GR3/11635 (United
Kingdom). AN is funded by the Ramón y Cajal Program (Spain)."
article_processing_charge: No
article_type: original
author:
- first_name: Arcadio
full_name: Navarro, Arcadio
last_name: Navarro
- first_name: Nicholas H
full_name: Barton, Nicholas H
id: 4880FE40-F248-11E8-B48F-1D18A9856A87
last_name: Barton
orcid: 0000-0002-8548-5240
citation:
ama: 'Navarro A, Barton NH. Accumulating postzygotic isolation genes in parapatry:
a new twist on chromosomal speciation. Evolution; International Journal of
Organic Evolution. 2003;57(3):447-459. doi:10.1111/j.0014-3820.2003.tb01537.x'
apa: 'Navarro, A., & Barton, N. H. (2003). Accumulating postzygotic isolation
genes in parapatry: a new twist on chromosomal speciation. Evolution; International
Journal of Organic Evolution. Wiley-Blackwell. https://doi.org/10.1111/j.0014-3820.2003.tb01537.x'
chicago: 'Navarro, Arcadio, and Nicholas H Barton. “Accumulating Postzygotic Isolation
Genes in Parapatry: A New Twist on Chromosomal Speciation.” Evolution; International
Journal of Organic Evolution. Wiley-Blackwell, 2003. https://doi.org/10.1111/j.0014-3820.2003.tb01537.x.'
ieee: 'A. Navarro and N. H. Barton, “Accumulating postzygotic isolation genes in
parapatry: a new twist on chromosomal speciation,” Evolution; International
Journal of Organic Evolution, vol. 57, no. 3. Wiley-Blackwell, pp. 447–459,
2003.'
ista: 'Navarro A, Barton NH. 2003. Accumulating postzygotic isolation genes in parapatry:
a new twist on chromosomal speciation. Evolution; International Journal of Organic
Evolution. 57(3), 447–459.'
mla: 'Navarro, Arcadio, and Nicholas H. Barton. “Accumulating Postzygotic Isolation
Genes in Parapatry: A New Twist on Chromosomal Speciation.” Evolution; International
Journal of Organic Evolution, vol. 57, no. 3, Wiley-Blackwell, 2003, pp. 447–59,
doi:10.1111/j.0014-3820.2003.tb01537.x.'
short: A. Navarro, N.H. Barton, Evolution; International Journal of Organic Evolution
57 (2003) 447–459.
date_created: 2018-12-11T12:07:52Z
date_published: 2003-03-01T00:00:00Z
date_updated: 2024-01-23T10:21:57Z
day: '01'
doi: 10.1111/j.0014-3820.2003.tb01537.x
extern: '1'
external_id:
pmid:
- '12703935 '
intvolume: ' 57'
issue: '3'
language:
- iso: eng
month: '03'
oa_version: None
page: 447 - 459
pmid: 1
publication: Evolution; International Journal of Organic Evolution
publication_identifier:
issn:
- 0014-3820
publication_status: published
publisher: Wiley-Blackwell
publist_id: '1840'
quality_controlled: '1'
scopus_import: '1'
status: public
title: 'Accumulating postzygotic isolation genes in parapatry: a new twist on chromosomal
speciation'
type: journal_article
user_id: ea97e931-d5af-11eb-85d4-e6957dddbf17
volume: 57
year: '2003'
...
---
_id: '4257'
abstract:
- lang: eng
text: Variation within a species may be structured both geographically and by genetic
background. We review the effects of such structuring on neutral variants, using
a framework based on the coalescent process. Short-term effects of sex differences
and age structure can be averaged out using fast timescale approximations, allowing
a simple general treatment of effective population size and migration. We consider
the effects of geographic structure on variation within and between local populations,
first in general terms, and then for specific migration models. We discuss the
close parallels between geographic structure and stable types of genetic structure
caused by selection, including balancing selection and background selection. The
effects of departures from stability, such as selective sweeps and population
bottlenecks, are also described. Methods for distinguishing population history
from the effects of ongoing gene flow are discussed. We relate the theoretical
results to observed patterns of variation in natural populations.
article_processing_charge: No
article_type: original
author:
- first_name: Brian
full_name: Charlesworth, Brian
last_name: Charlesworth
- first_name: Deborah
full_name: Charlesworth, Deborah
last_name: Charlesworth
- first_name: Nicholas H
full_name: Barton, Nicholas H
id: 4880FE40-F248-11E8-B48F-1D18A9856A87
last_name: Barton
orcid: 0000-0002-8548-5240
citation:
ama: Charlesworth B, Charlesworth D, Barton NH. The effects of genetic and geographic
structure on neutral variation. Annual Review of Ecology and Systematics.
2003;34:99-125. doi:10.1146/annurev.ecolsys.34.011802.132359
apa: Charlesworth, B., Charlesworth, D., & Barton, N. H. (2003). The effects
of genetic and geographic structure on neutral variation. Annual Review of
Ecology and Systematics. Annual Reviews. https://doi.org/10.1146/annurev.ecolsys.34.011802.132359
chicago: Charlesworth, Brian, Deborah Charlesworth, and Nicholas H Barton. “The
Effects of Genetic and Geographic Structure on Neutral Variation.” Annual Review
of Ecology and Systematics. Annual Reviews, 2003. https://doi.org/10.1146/annurev.ecolsys.34.011802.132359.
ieee: B. Charlesworth, D. Charlesworth, and N. H. Barton, “The effects of genetic
and geographic structure on neutral variation,” Annual Review of Ecology and
Systematics, vol. 34. Annual Reviews, pp. 99–125, 2003.
ista: Charlesworth B, Charlesworth D, Barton NH. 2003. The effects of genetic and
geographic structure on neutral variation. Annual Review of Ecology and Systematics.
34, 99–125.
mla: Charlesworth, Brian, et al. “The Effects of Genetic and Geographic Structure
on Neutral Variation.” Annual Review of Ecology and Systematics, vol. 34,
Annual Reviews, 2003, pp. 99–125, doi:10.1146/annurev.ecolsys.34.011802.132359.
short: B. Charlesworth, D. Charlesworth, N.H. Barton, Annual Review of Ecology and
Systematics 34 (2003) 99–125.
date_created: 2018-12-11T12:07:53Z
date_published: 2003-11-01T00:00:00Z
date_updated: 2024-01-23T10:15:44Z
day: '01'
doi: 10.1146/annurev.ecolsys.34.011802.132359
extern: '1'
intvolume: ' 34'
language:
- iso: eng
month: '11'
oa_version: None
page: 99 - 125
publication: Annual Review of Ecology and Systematics
publication_identifier:
issn:
- 1543-592X
publication_status: published
publisher: Annual Reviews
publist_id: '1839'
quality_controlled: '1'
status: public
title: The effects of genetic and geographic structure on neutral variation
type: journal_article
user_id: ea97e931-d5af-11eb-85d4-e6957dddbf17
volume: 34
year: '2003'
...
---
_id: '4256'
abstract:
- lang: eng
text: Artificial Life models may shed new light on the long-standing challenge for
evolutionary biology of explaining the origins of complex organs. Real progress
on this issue, however, requires Artificial Life researchers to take seriously
the tools and insights from population genetics.
article_processing_charge: No
article_type: original
author:
- first_name: Nicholas H
full_name: Barton, Nicholas H
id: 4880FE40-F248-11E8-B48F-1D18A9856A87
last_name: Barton
orcid: 0000-0002-8548-5240
- first_name: Willem
full_name: Zuidema, Willem
last_name: Zuidema
citation:
ama: Barton NH, Zuidema W. The erratic path towards complexity. Current Biology.
2003;13(16):R649-R651. doi:10.1016/S0960-9822(03)00573-6
apa: Barton, N. H., & Zuidema, W. (2003). The erratic path towards complexity.
Current Biology. Cell Press. https://doi.org/10.1016/S0960-9822(03)00573-6
chicago: Barton, Nicholas H, and Willem Zuidema. “The Erratic Path towards Complexity.”
Current Biology. Cell Press, 2003. https://doi.org/10.1016/S0960-9822(03)00573-6.
ieee: N. H. Barton and W. Zuidema, “The erratic path towards complexity,” Current
Biology, vol. 13, no. 16. Cell Press, pp. R649–R651, 2003.
ista: Barton NH, Zuidema W. 2003. The erratic path towards complexity. Current Biology.
13(16), R649–R651.
mla: Barton, Nicholas H., and Willem Zuidema. “The Erratic Path towards Complexity.”
Current Biology, vol. 13, no. 16, Cell Press, 2003, pp. R649–51, doi:10.1016/S0960-9822(03)00573-6.
short: N.H. Barton, W. Zuidema, Current Biology 13 (2003) R649–R651.
date_created: 2018-12-11T12:07:53Z
date_published: 2003-08-19T00:00:00Z
date_updated: 2024-01-23T09:41:33Z
day: '19'
doi: 10.1016/S0960-9822(03)00573-6
extern: '1'
intvolume: ' 13'
issue: '16'
language:
- iso: eng
month: '08'
oa_version: Published Version
page: R649 - R651
publication: Current Biology
publication_identifier:
issn:
- 0960-9822
publication_status: published
publisher: Cell Press
publist_id: '1838'
quality_controlled: '1'
scopus_import: '1'
status: public
title: The erratic path towards complexity
type: journal_article
user_id: ea97e931-d5af-11eb-85d4-e6957dddbf17
volume: 13
year: '2003'
...
---
_id: '4255'
abstract:
- lang: eng
text: 'Humans and their closest evolutionary relatives, the chimpanzees, differ
in ∼1.24% of their genomic DNA sequences. The fraction of these changes accumulated
during the speciation processes that have separated the two lineages may be of
special relevance in understanding the basis of their differences. We analyzed
human and chimpanzee sequence data to search for the patterns of divergence and
polymorphism predicted by a theoretical model of speciation. According to the
model, positively selected changes should accumulate in chromosomes that present
fixed structural differences, such as inversions, between the two species. Protein
evolution was more than 2.2 times faster in chromosomes that had undergone structural
rearrangements compared with colinear chromosomes. Also, nucleotide variability
is slightly lower in rearranged chromosomes. These patterns of divergence and
polymorphism may be, at least in part, the molecular footprint of speciation events
in the human and chimpanzee lineages. '
article_processing_charge: No
article_type: original
author:
- first_name: Arcadio
full_name: Navarro, Arcadio
last_name: Navarro
- first_name: Nicholas H
full_name: Barton, Nicholas H
id: 4880FE40-F248-11E8-B48F-1D18A9856A87
last_name: Barton
orcid: 0000-0002-8548-5240
citation:
ama: Navarro A, Barton NH. Chromosomal speciation and molecular divergence -- Accelerated
evolution in rearranged chromosomes. Science. 2003;300(5617):321-324. doi:10.1126/science.1080600
apa: Navarro, A., & Barton, N. H. (2003). Chromosomal speciation and molecular
divergence -- Accelerated evolution in rearranged chromosomes. Science.
American Association for the Advancement of Science. https://doi.org/10.1126/science.1080600
chicago: Navarro, Arcadio, and Nicholas H Barton. “Chromosomal Speciation and Molecular
Divergence -- Accelerated Evolution in Rearranged Chromosomes.” Science.
American Association for the Advancement of Science, 2003. https://doi.org/10.1126/science.1080600 .
ieee: A. Navarro and N. H. Barton, “Chromosomal speciation and molecular divergence
-- Accelerated evolution in rearranged chromosomes,” Science, vol. 300,
no. 5617. American Association for the Advancement of Science, pp. 321–324, 2003.
ista: Navarro A, Barton NH. 2003. Chromosomal speciation and molecular divergence
-- Accelerated evolution in rearranged chromosomes. Science. 300(5617), 321–324.
mla: Navarro, Arcadio, and Nicholas H. Barton. “Chromosomal Speciation and Molecular
Divergence -- Accelerated Evolution in Rearranged Chromosomes.” Science,
vol. 300, no. 5617, American Association for the Advancement of Science, 2003,
pp. 321–24, doi:10.1126/science.1080600
.
short: A. Navarro, N.H. Barton, Science 300 (2003) 321–324.
date_created: 2018-12-11T12:07:53Z
date_published: 2003-04-11T00:00:00Z
date_updated: 2024-02-26T13:37:51Z
day: '11'
doi: '10.1126/science.1080600 '
extern: '1'
external_id:
pmid:
- ' 12690198'
intvolume: ' 300'
issue: '5617'
language:
- iso: eng
month: '04'
oa_version: None
page: 321 - 324
pmid: 1
publication: Science
publication_identifier:
issn:
- 0036-8075
publication_status: published
publisher: American Association for the Advancement of Science
publist_id: '1841'
quality_controlled: '1'
scopus_import: '1'
status: public
title: Chromosomal speciation and molecular divergence -- Accelerated evolution in
rearranged chromosomes
type: journal_article
user_id: ea97e931-d5af-11eb-85d4-e6957dddbf17
volume: 300
year: '2003'
...
---
_id: '4146'
abstract:
- lang: eng
text: During vertebrate gastrulation, highly coordinated cellular rearrangements
lead to the formation of the three germ layers, ectoderm, mesoderm and endoderm.
In zebrafish, silberblick (slb)/wnt11 regulates normal gastrulation movements
by activating a signalling pathway similar to the Frizzled-signalling pathway,
which establishes epithelial planar cell polarity (PCP) in Drosophila. However,
the cellular mechanisms by which slb/wnt11 functions during zebrafish gastrulation
are still unclear. Using high-resolution two-photon confocal imaging followed
by computer-assisted reconstruction and motion analysis, we have analysed the
movement and morphology of individual cells in three dimensions during the course
of gastrulation. We show that in slb-mutant embryos, hypoblast cells within the
forming germ ring have slower, less directed migratory movements at the onset
of gastrulation. These aberrant cell movements are accompanied by defects in the
orientation of cellular processes along the individual movement directions of
these cells. We conclude that slb/wnt11-mediated orientation of cellular processes
plays a role in facilitating and stabilising movements of hypoblast cells in the
germ ring, thereby pointing at a novel function of the slb/wnt11 signalling pathway
for the regulation of migratory cell movements at early stages of gastrulation.
acknowledgement: 'We thank Jennifer Geiger, Mathias Köppen, Christian Dahmann and
Marcos Gonzalez-Gaitan for helpful comments on earlier versions of this manuscript,Beate
Kilian for technical assistance, Ugur Yalcin, Katrin Anczok and Viktor Schnabel
for help with the image analysis, Vinzenz Link for programming Excel Macros and
Harald Brush-Janovjak for extensive reviews of the statistics part of this work.
We are grateful to Kurt Anderson and Jan Peychl for help with the confocal microscopy.
P.J.H., E.V. and D.R.S. are supported by NIH grant HD-18577, The W.M Keck Foundation
and the Developmental Studies Hybridoma Bank(DSHB), P.J.H. by The American Cancer
Society (grant # PF-01-110-01-CSM),M.L.C. and S.W.W. by the Wellcome Trust, M.T.
by an MRC Career Development Award, and F.U. and C.P.H. by an Emmy-Noether-Fellowship
from the DFG.'
article_processing_charge: No
article_type: original
author:
- first_name: Florian
full_name: Ulrich, Florian
last_name: Ulrich
- first_name: Miguel
full_name: Concha, Miguel
last_name: Concha
- first_name: Paul
full_name: Heid, Paul
last_name: Heid
- first_name: Ed
full_name: Voss, Ed
last_name: Voss
- first_name: Sabine
full_name: Witzel, Sabine
last_name: Witzel
- first_name: Henry
full_name: Roehl, Henry
last_name: Roehl
- first_name: Masazumi
full_name: Tada, Masazumi
last_name: Tada
- first_name: Stephen
full_name: Wilson, Stephen
last_name: Wilson
- first_name: Richard
full_name: Adams, Richard
last_name: Adams
- first_name: David
full_name: Soll, David
last_name: Soll
- first_name: Carl-Philipp J
full_name: Heisenberg, Carl-Philipp J
id: 39427864-F248-11E8-B48F-1D18A9856A87
last_name: Heisenberg
orcid: 0000-0002-0912-4566
citation:
ama: Ulrich F, Concha M, Heid P, et al. Slb/Wnt11 controls hypoblast cell migration
and morphogenesis at the onset of zebrafish gastrulation. Development.
2003;130(22):5375-5384. doi:10.1242/dev.00758
apa: Ulrich, F., Concha, M., Heid, P., Voss, E., Witzel, S., Roehl, H., … Heisenberg,
C.-P. J. (2003). Slb/Wnt11 controls hypoblast cell migration and morphogenesis
at the onset of zebrafish gastrulation. Development. Company of Biologists.
https://doi.org/10.1242/dev.00758
chicago: Ulrich, Florian, Miguel Concha, Paul Heid, Ed Voss, Sabine Witzel, Henry
Roehl, Masazumi Tada, et al. “Slb/Wnt11 Controls Hypoblast Cell Migration and
Morphogenesis at the Onset of Zebrafish Gastrulation.” Development. Company
of Biologists, 2003. https://doi.org/10.1242/dev.00758.
ieee: F. Ulrich et al., “Slb/Wnt11 controls hypoblast cell migration and
morphogenesis at the onset of zebrafish gastrulation,” Development, vol.
130, no. 22. Company of Biologists, pp. 5375–5384, 2003.
ista: Ulrich F, Concha M, Heid P, Voss E, Witzel S, Roehl H, Tada M, Wilson S, Adams
R, Soll D, Heisenberg C-PJ. 2003. Slb/Wnt11 controls hypoblast cell migration
and morphogenesis at the onset of zebrafish gastrulation. Development. 130(22),
5375–5384.
mla: Ulrich, Florian, et al. “Slb/Wnt11 Controls Hypoblast Cell Migration and Morphogenesis
at the Onset of Zebrafish Gastrulation.” Development, vol. 130, no. 22,
Company of Biologists, 2003, pp. 5375–84, doi:10.1242/dev.00758.
short: F. Ulrich, M. Concha, P. Heid, E. Voss, S. Witzel, H. Roehl, M. Tada, S.
Wilson, R. Adams, D. Soll, C.-P.J. Heisenberg, Development 130 (2003) 5375–5384.
date_created: 2018-12-11T12:07:13Z
date_published: 2003-11-15T00:00:00Z
date_updated: 2024-02-27T10:14:21Z
day: '15'
doi: 10.1242/dev.00758
extern: '1'
external_id:
pmid:
- ' PMC1414802'
intvolume: ' 130'
issue: '22'
language:
- iso: eng
main_file_link:
- open_access: '1'
url: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1414802/
month: '11'
oa: 1
oa_version: None
page: 5375 - 5384
pmid: 1
publication: Development
publication_identifier:
issn:
- 1011-6370
publication_status: published
publisher: Company of Biologists
publist_id: '1975'
quality_controlled: '1'
scopus_import: '1'
status: public
title: Slb/Wnt11 controls hypoblast cell migration and morphogenesis at the onset
of zebrafish gastrulation
type: journal_article
user_id: ea97e931-d5af-11eb-85d4-e6957dddbf17
volume: 130
year: '2003'
...
---
_id: '4169'
abstract:
- lang: eng
text: 'Background: During vertebrate gastrulation, cell polarization and migration
are core components in the cellular rearrangements that lead to the formation
of the three germ layers, ectoderm, mesoderm, and endoderm. Previous studies have
implicated the Wnt/planar cell polarity (PCP) signaling pathway in controlling
cell morphology and movement during gastrulation. However, cell polarization and
directed cell migration are reduced but not completely abolished in the absence
of Wnt/PCP signals; this observation indicates that other signaling pathways must
be involved. Results: We show that Phosphoinositide 3-Kinases (PI3Ks) are required
at the onset of zebrafish gastrulation in mesendodermal cells for process formation
and cell polarization. Platelet Derived Growth Factor (PDGF) functions upstream
of PI3K, while Protein Kinase B (PKB), a downstream effector of PI3K activity,
localizes to the leading edge of migrating mesendodermal cells. In the absence
of PI3K activity, PKB localization and cell polarization are strongly reduced
in mesendodermal cells and are followed by slower but still highly coordinated
and directed movements of these cells. Conclusions: We have identified a novel
role of a signaling pathway comprised of PDGF, PI3K, and PKB in the control of
morphogenetic cell movements during gastrulation. Furthermore, our findings provide
insight into the relationship between cell polarization and directed cell migration
at the onset of zebrafish gastrulation.'
acknowledgement: 'We would like to thank Jennifer Geiger, Juan Hurl& Hannu Mansu-koski,
Florian Raible, Marino Zerial, Steve Wilson, and Kurt Anderson for critical reading
of earlier versions of this manuscript. We thank Erez Raz, Bart Vanhaesebroeck,
and Lukas Roth for sending us the pCS2-PH-GFP-nos, the p1IOCAAX, and the pCS2-actin-GFP
constructs, respectively. We are grateful to Marino Zerial and his lab for encouraging
us to start this work and providing us with the dnP13K construct and to Florian
Ulrich and Franziska Friedrich for help with the confocal microscope and artwork,
respectively. We thank Gunter Junghanns and Evelyn Lehmann for excellent fish care.
C.-P.H. is supported by an Emmy-Noother-Fellowship from the Deutsche Forschungsgemeinschaft. '
article_processing_charge: No
article_type: original
author:
- first_name: Juan
full_name: Montero, Juan
last_name: Montero
- first_name: Beate
full_name: Kilian, Beate
last_name: Kilian
- first_name: Joanne
full_name: Chan, Joanne
last_name: Chan
- first_name: Peter
full_name: Bayliss, Peter
last_name: Bayliss
- first_name: Carl-Philipp J
full_name: Heisenberg, Carl-Philipp J
id: 39427864-F248-11E8-B48F-1D18A9856A87
last_name: Heisenberg
orcid: 0000-0002-0912-4566
citation:
ama: Montero J, Kilian B, Chan J, Bayliss P, Heisenberg C-PJ. Phosphoinositide 3-kinase
is required for process outgrowth and cell polarization of gastrulating mesendodermal
cells. Current Biology. 2003;13(15):1279-1289. doi:10.1016/S0960-9822(03)00505-0
apa: Montero, J., Kilian, B., Chan, J., Bayliss, P., & Heisenberg, C.-P. J.
(2003). Phosphoinositide 3-kinase is required for process outgrowth and cell polarization
of gastrulating mesendodermal cells. Current Biology. Cell Press. https://doi.org/10.1016/S0960-9822(03)00505-0
chicago: Montero, Juan, Beate Kilian, Joanne Chan, Peter Bayliss, and Carl-Philipp
J Heisenberg. “Phosphoinositide 3-Kinase Is Required for Process Outgrowth and
Cell Polarization of Gastrulating Mesendodermal Cells.” Current Biology.
Cell Press, 2003. https://doi.org/10.1016/S0960-9822(03)00505-0.
ieee: J. Montero, B. Kilian, J. Chan, P. Bayliss, and C.-P. J. Heisenberg, “Phosphoinositide
3-kinase is required for process outgrowth and cell polarization of gastrulating
mesendodermal cells,” Current Biology, vol. 13, no. 15. Cell Press, pp.
1279–1289, 2003.
ista: Montero J, Kilian B, Chan J, Bayliss P, Heisenberg C-PJ. 2003. Phosphoinositide
3-kinase is required for process outgrowth and cell polarization of gastrulating
mesendodermal cells. Current Biology. 13(15), 1279–1289.
mla: Montero, Juan, et al. “Phosphoinositide 3-Kinase Is Required for Process Outgrowth
and Cell Polarization of Gastrulating Mesendodermal Cells.” Current Biology,
vol. 13, no. 15, Cell Press, 2003, pp. 1279–89, doi:10.1016/S0960-9822(03)00505-0.
short: J. Montero, B. Kilian, J. Chan, P. Bayliss, C.-P.J. Heisenberg, Current Biology
13 (2003) 1279–1289.
date_created: 2018-12-11T12:07:22Z
date_published: 2003-08-05T00:00:00Z
date_updated: 2024-02-27T10:03:37Z
day: '05'
doi: 10.1016/S0960-9822(03)00505-0
extern: '1'
external_id:
pmid:
- ' 12906787'
intvolume: ' 13'
issue: '15'
language:
- iso: eng
month: '08'
oa_version: None
page: 1279 - 1289
pmid: 1
publication: Current Biology
publication_identifier:
eissn:
- 1879-0445
issn:
- 0960-9822
publication_status: published
publisher: Cell Press
publist_id: '1950'
quality_controlled: '1'
scopus_import: '1'
status: public
title: Phosphoinositide 3-kinase is required for process outgrowth and cell polarization
of gastrulating mesendodermal cells
type: journal_article
user_id: ea97e931-d5af-11eb-85d4-e6957dddbf17
volume: 13
year: '2003'
...
---
_id: '4185'
abstract:
- lang: eng
text: Wnt genes play important roles in regulating patterning and morphogenesis
during vertebrate gastrulation. In zebrafish, slb/wnt11 is required for convergence
and extension movements, but not cell fate specification during gastrulation.
To determine if other Wnt genes functionally interact with slb/wnt11, we analysed
the role of ppt/wnt5 during zebrafish gastrulation. ppt/wnt5 is maternally provided
and zygotically expressed at all stages during gastrulation. The analysis of ppt
mutant embryos reveals that Ppt/Wnt5 regulates cell elongation and convergent
extension movements in posterior regions of the gastrula, while its function in
more anterior regions is largely redundant to that of Slb/Wnt11. Frizzled-2 functions
downstream of ppt/wnt5, indicating that it might act as a receptor for Ppt/Wnt5
in this process. The characterisation of the role of Ppt/Wnt5 provides insight
into the functional diversity of Wnt genes in regulating vertebrate gastrulation
movements. (C) 2003 Elsevier Science Ireland Ltd. All rights reserved.
acknowledgement: We thank Michael Brand, Florian Raible, Gerlinde Reim, Tobias Langenberg,
Jennifer Geiger and Kate Poole for helpful comments on earlier versions of this
manuscript. We are grateful to Henry Roehl and Christiane Nüsslein Volhard for sending
us the ppt mutant stock. M.T. was supported by a Career Development Fellowship from
the MRC. B.K., H.M. and C.P.H. are supported by an Emmy Noether-Fellowship from
the DFG.
article_processing_charge: No
article_type: original
author:
- first_name: Beate
full_name: Kilian, Beate
last_name: Kilian
- first_name: Hannu
full_name: Mansukoski, Hannu
last_name: Mansukoski
- first_name: Filipa
full_name: Barbosa, Filipa
last_name: Barbosa
- first_name: Florian
full_name: Ulrich, Florian
last_name: Ulrich
- first_name: Masazumi
full_name: Tada, Masazumi
last_name: Tada
- first_name: Carl-Philipp J
full_name: Heisenberg, Carl-Philipp J
id: 39427864-F248-11E8-B48F-1D18A9856A87
last_name: Heisenberg
orcid: 0000-0002-0912-4566
citation:
ama: Kilian B, Mansukoski H, Barbosa F, Ulrich F, Tada M, Heisenberg C-PJ. The role
of Ppt/Wnt5 in regulating cell shape and movement during zebrafish gastrulation.
Mechanisms of Development. 2003;120(4):467-476. doi:10.1016/S0925-4773(03)00004-2
apa: Kilian, B., Mansukoski, H., Barbosa, F., Ulrich, F., Tada, M., & Heisenberg,
C.-P. J. (2003). The role of Ppt/Wnt5 in regulating cell shape and movement during
zebrafish gastrulation. Mechanisms of Development. Elsevier. https://doi.org/10.1016/S0925-4773(03)00004-2
chicago: Kilian, Beate, Hannu Mansukoski, Filipa Barbosa, Florian Ulrich, Masazumi
Tada, and Carl-Philipp J Heisenberg. “The Role of Ppt/Wnt5 in Regulating Cell
Shape and Movement during Zebrafish Gastrulation.” Mechanisms of Development.
Elsevier, 2003. https://doi.org/10.1016/S0925-4773(03)00004-2.
ieee: B. Kilian, H. Mansukoski, F. Barbosa, F. Ulrich, M. Tada, and C.-P. J. Heisenberg,
“The role of Ppt/Wnt5 in regulating cell shape and movement during zebrafish gastrulation,”
Mechanisms of Development, vol. 120, no. 4. Elsevier, pp. 467–476, 2003.
ista: Kilian B, Mansukoski H, Barbosa F, Ulrich F, Tada M, Heisenberg C-PJ. 2003.
The role of Ppt/Wnt5 in regulating cell shape and movement during zebrafish gastrulation.
Mechanisms of Development. 120(4), 467–476.
mla: Kilian, Beate, et al. “The Role of Ppt/Wnt5 in Regulating Cell Shape and Movement
during Zebrafish Gastrulation.” Mechanisms of Development, vol. 120, no.
4, Elsevier, 2003, pp. 467–76, doi:10.1016/S0925-4773(03)00004-2.
short: B. Kilian, H. Mansukoski, F. Barbosa, F. Ulrich, M. Tada, C.-P.J. Heisenberg,
Mechanisms of Development 120 (2003) 467–476.
date_created: 2018-12-11T12:07:27Z
date_published: 2003-04-01T00:00:00Z
date_updated: 2024-02-27T09:46:39Z
day: '01'
doi: 10.1016/S0925-4773(03)00004-2
extern: '1'
external_id:
pmid:
- '12676324 '
intvolume: ' 120'
issue: '4'
language:
- iso: eng
month: '04'
oa_version: None
page: 467 - 476
pmid: 1
publication: Mechanisms of Development
publication_identifier:
issn:
- 0925-4773
publication_status: published
publisher: Elsevier
publist_id: '1934'
quality_controlled: '1'
scopus_import: '1'
status: public
title: The role of Ppt/Wnt5 in regulating cell shape and movement during zebrafish
gastrulation
type: journal_article
user_id: ea97e931-d5af-11eb-85d4-e6957dddbf17
volume: 120
year: '2003'
...
---
_id: '3992'
abstract:
- lang: eng
text: Computing the volume occupied by individual atoms in macromolecular structures
has been the subject of research for several decades. This interest has grown
in the recent years, because weighted volumes are widely used in implicit solvent
models. Applications of the latter in molecular mechanics simulations require
that the derivatives of these weighted volumes be known. In this article, we give
a formula for the volume derivative of a molecule modeled as a space-filling diagram
made up of balls in motion. The formula is given in terms of the weights, radii,
and distances between the centers as well as the sizes of the facets of the power
diagram restricted to the space-filling diagram. Special attention is given to
the detection and treatment of singularities as well as discontinuities of the
derivative.
article_processing_charge: No
article_type: original
author:
- first_name: Herbert
full_name: Edelsbrunner, Herbert
id: 3FB178DA-F248-11E8-B48F-1D18A9856A87
last_name: Edelsbrunner
orcid: 0000-0002-9823-6833
- first_name: Patrice
full_name: Koehl, Patrice
last_name: Koehl
citation:
ama: Edelsbrunner H, Koehl P. The weighted-volume derivative of a space-filling
diagram. PNAS. 2003;100(5):2203-2208. doi:10.1073/pnas.0537830100
apa: Edelsbrunner, H., & Koehl, P. (2003). The weighted-volume derivative of
a space-filling diagram. PNAS. National Academy of Sciences. https://doi.org/10.1073/pnas.0537830100
chicago: Edelsbrunner, Herbert, and Patrice Koehl. “The Weighted-Volume Derivative
of a Space-Filling Diagram.” PNAS. National Academy of Sciences, 2003.
https://doi.org/10.1073/pnas.0537830100.
ieee: H. Edelsbrunner and P. Koehl, “The weighted-volume derivative of a space-filling
diagram,” PNAS, vol. 100, no. 5. National Academy of Sciences, pp. 2203–2208,
2003.
ista: Edelsbrunner H, Koehl P. 2003. The weighted-volume derivative of a space-filling
diagram. PNAS. 100(5), 2203–2208.
mla: Edelsbrunner, Herbert, and Patrice Koehl. “The Weighted-Volume Derivative of
a Space-Filling Diagram.” PNAS, vol. 100, no. 5, National Academy of Sciences,
2003, pp. 2203–08, doi:10.1073/pnas.0537830100.
short: H. Edelsbrunner, P. Koehl, PNAS 100 (2003) 2203–2208.
date_created: 2018-12-11T12:06:19Z
date_published: 2003-03-04T00:00:00Z
date_updated: 2024-02-27T12:31:59Z
day: '04'
doi: 10.1073/pnas.0537830100
extern: '1'
external_id:
pmid:
- '12601153'
intvolume: ' 100'
issue: '5'
language:
- iso: eng
main_file_link:
- open_access: '1'
url: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC151318/
month: '03'
oa: 1
oa_version: Published Version
page: 2203 - 2208
pmid: 1
publication: PNAS
publication_identifier:
issn:
- 0027-8424
publication_status: published
publisher: National Academy of Sciences
publist_id: '2133'
quality_controlled: '1'
scopus_import: '1'
status: public
title: The weighted-volume derivative of a space-filling diagram
type: journal_article
user_id: ea97e931-d5af-11eb-85d4-e6957dddbf17
volume: 100
year: '2003'
...
---
_id: '3999'
abstract:
- lang: eng
text: We introduce relaxed scheduling as a paradigm for mesh maintenance and demonstrate
its applicability to triangulating a skin surface in R-3.
acknowledgement: NSF under grant CCR-00- 86013.
alternative_title:
- LNCS
article_processing_charge: No
author:
- first_name: Herbert
full_name: Edelsbrunner, Herbert
id: 3FB178DA-F248-11E8-B48F-1D18A9856A87
last_name: Edelsbrunner
orcid: 0000-0002-9823-6833
- first_name: Alper
full_name: Üngör, Alper
last_name: Üngör
citation:
ama: 'Edelsbrunner H, Üngör A. Relaxed scheduling in dynamic skin triangulation.
In: Proceedings of the Japanese Conference on Discrete and Computational Geometry
. Vol 2866. Springer; 2003:135-151. doi:10.1007/978-3-540-44400-8_14'
apa: 'Edelsbrunner, H., & Üngör, A. (2003). Relaxed scheduling in dynamic skin
triangulation. In Proceedings of the Japanese Conference on Discrete and Computational
Geometry (Vol. 2866, pp. 135–151). Tokyo, Japan: Springer. https://doi.org/10.1007/978-3-540-44400-8_14'
chicago: Edelsbrunner, Herbert, and Alper Üngör. “Relaxed Scheduling in Dynamic
Skin Triangulation.” In Proceedings of the Japanese Conference on Discrete
and Computational Geometry , 2866:135–51. Springer, 2003. https://doi.org/10.1007/978-3-540-44400-8_14.
ieee: H. Edelsbrunner and A. Üngör, “Relaxed scheduling in dynamic skin triangulation,”
in Proceedings of the Japanese Conference on Discrete and Computational Geometry
, Tokyo, Japan, 2003, vol. 2866, pp. 135–151.
ista: 'Edelsbrunner H, Üngör A. 2003. Relaxed scheduling in dynamic skin triangulation.
Proceedings of the Japanese Conference on Discrete and Computational Geometry
. JCDCG: Japanese Conference on Discrete and Computational Geometry, LNCS, vol.
2866, 135–151.'
mla: Edelsbrunner, Herbert, and Alper Üngör. “Relaxed Scheduling in Dynamic Skin
Triangulation.” Proceedings of the Japanese Conference on Discrete and Computational
Geometry , vol. 2866, Springer, 2003, pp. 135–51, doi:10.1007/978-3-540-44400-8_14.
short: H. Edelsbrunner, A. Üngör, in:, Proceedings of the Japanese Conference on
Discrete and Computational Geometry , Springer, 2003, pp. 135–151.
conference:
end_date: 2002-12-09
location: Tokyo, Japan
name: 'JCDCG: Japanese Conference on Discrete and Computational Geometry'
start_date: 2002-12-06
date_created: 2018-12-11T12:06:21Z
date_published: 2003-12-16T00:00:00Z
date_updated: 2024-02-27T11:07:15Z
day: '16'
doi: 10.1007/978-3-540-44400-8_14
extern: '1'
intvolume: ' 2866'
language:
- iso: eng
month: '12'
oa_version: None
page: 135 - 151
publication: 'Proceedings of the Japanese Conference on Discrete and Computational
Geometry '
publication_identifier:
isbn:
- '9783540207764'
publication_status: published
publisher: Springer
publist_id: '2127'
quality_controlled: '1'
scopus_import: '1'
status: public
title: Relaxed scheduling in dynamic skin triangulation
type: conference
user_id: ea97e931-d5af-11eb-85d4-e6957dddbf17
volume: 2866
year: '2003'
...
---
_id: '3997'
abstract:
- lang: eng
text: We combine topological and geometric methods to construct a multi-resolution
data structure for functions over two-dimensional domains. Starting with the Morse-Smale
complex, we construct a topological hierarchy by progressively canceling critical
points in pairs. Concurrently, we create a geometric hierarchy by adapting the
geometry to the changes in topology. The data structure supports mesh traversal
operations similarly to traditional multi-resolution representations.
acknowledgement: This work was performed under the auspices of the U. S. Department
of Energy by University of California Lawrence Livermore National Laboratory under
contract No. W-7405-Eng-48. H. Edelsbrunner is partially supported by the National
Science Foundation (NFS) under grants EIA-99-72879 and CCR-00-86013. B. Hamann is
supported by the NSF under contract ACI 9624034, through the LSSDSV program under
contract ACI 9982251, and through the NPACI; the National Institute of Mental Health
and the NSF under contract NIMH 2 P20 MH60975-06A2; the Lawrence Livermore National
Laboratory under ASCI ASAP Level-2 Memorandum Agreement B347878 and under Memorandum
Agreement B503159.
article_processing_charge: No
author:
- first_name: Peer
full_name: Bremer, Peer
last_name: Bremer
- first_name: Herbert
full_name: Edelsbrunner, Herbert
id: 3FB178DA-F248-11E8-B48F-1D18A9856A87
last_name: Edelsbrunner
orcid: 0000-0002-9823-6833
- first_name: Bernd
full_name: Hamann, Bernd
last_name: Hamann
- first_name: Valerio
full_name: Pascucci, Valerio
last_name: Pascucci
citation:
ama: 'Bremer P, Edelsbrunner H, Hamann B, Pascucci V. A multi-resolution data structure
for two-dimensional Morse-Smale functions. In: Proceedings of the 14th IEEE
Conference on Visualization . IEEE; 2003:139-146. doi:10.1109/VISUAL.2003.1250365'
apa: 'Bremer, P., Edelsbrunner, H., Hamann, B., & Pascucci, V. (2003). A multi-resolution
data structure for two-dimensional Morse-Smale functions. In Proceedings of
the 14th IEEE Conference on Visualization (pp. 139–146). Seattle, WA, USA
: IEEE. https://doi.org/10.1109/VISUAL.2003.1250365'
chicago: Bremer, Peer, Herbert Edelsbrunner, Bernd Hamann, and Valerio Pascucci.
“A Multi-Resolution Data Structure for Two-Dimensional Morse-Smale Functions.”
In Proceedings of the 14th IEEE Conference on Visualization , 139–46. IEEE,
2003. https://doi.org/10.1109/VISUAL.2003.1250365.
ieee: P. Bremer, H. Edelsbrunner, B. Hamann, and V. Pascucci, “A multi-resolution
data structure for two-dimensional Morse-Smale functions,” in Proceedings of
the 14th IEEE Conference on Visualization , Seattle, WA, USA , 2003, pp. 139–146.
ista: 'Bremer P, Edelsbrunner H, Hamann B, Pascucci V. 2003. A multi-resolution
data structure for two-dimensional Morse-Smale functions. Proceedings of the 14th
IEEE Conference on Visualization . VIS: IEEE Visualization, 139–146.'
mla: Bremer, Peer, et al. “A Multi-Resolution Data Structure for Two-Dimensional
Morse-Smale Functions.” Proceedings of the 14th IEEE Conference on Visualization
, IEEE, 2003, pp. 139–46, doi:10.1109/VISUAL.2003.1250365.
short: P. Bremer, H. Edelsbrunner, B. Hamann, V. Pascucci, in:, Proceedings of the
14th IEEE Conference on Visualization , IEEE, 2003, pp. 139–146.
conference:
end_date: 2003-10-24
location: 'Seattle, WA, USA '
name: 'VIS: IEEE Visualization'
start_date: 2003-10-19
date_created: 2018-12-11T12:06:21Z
date_published: 2003-08-01T00:00:00Z
date_updated: 2024-02-27T11:12:50Z
day: '01'
doi: 10.1109/VISUAL.2003.1250365
extern: '1'
language:
- iso: eng
month: '08'
oa_version: None
page: 139 - 146
publication: 'Proceedings of the 14th IEEE Conference on Visualization '
publication_identifier:
isbn:
- '0780381203'
publication_status: published
publisher: IEEE
publist_id: '2131'
quality_controlled: '1'
scopus_import: '1'
status: public
title: A multi-resolution data structure for two-dimensional Morse-Smale functions
type: conference
user_id: ea97e931-d5af-11eb-85d4-e6957dddbf17
year: '2003'
...
---
_id: '4168'
abstract:
- lang: eng
text: Recent studies show that signaling through integrin receptors is required
for normal cell movements during Xenopus gastrulation. Integrins function in this
process by modulating the activity of cadherin adhesion molecules within tissues
undergoing convergence and extension movements.
article_processing_charge: No
article_type: original
author:
- first_name: Juan
full_name: Montero, Juan
last_name: Montero
- first_name: Carl-Philipp J
full_name: Heisenberg, Carl-Philipp J
id: 39427864-F248-11E8-B48F-1D18A9856A87
last_name: Heisenberg
orcid: 0000-0002-0912-4566
citation:
ama: Montero J, Heisenberg C-PJ. Adhesive crosstalk in gastrulation. Developmental
Cell. 2003;5(2):190-191. doi:10.1016/S1534-5807(03)00235-1
apa: Montero, J., & Heisenberg, C.-P. J. (2003). Adhesive crosstalk in gastrulation.
Developmental Cell. Cell Press. https://doi.org/10.1016/S1534-5807(03)00235-1
chicago: Montero, Juan, and Carl-Philipp J Heisenberg. “Adhesive Crosstalk in Gastrulation.”
Developmental Cell. Cell Press, 2003. https://doi.org/10.1016/S1534-5807(03)00235-1.
ieee: J. Montero and C.-P. J. Heisenberg, “Adhesive crosstalk in gastrulation,”
Developmental Cell, vol. 5, no. 2. Cell Press, pp. 190–191, 2003.
ista: Montero J, Heisenberg C-PJ. 2003. Adhesive crosstalk in gastrulation. Developmental
Cell. 5(2), 190–191.
mla: Montero, Juan, and Carl-Philipp J. Heisenberg. “Adhesive Crosstalk in Gastrulation.”
Developmental Cell, vol. 5, no. 2, Cell Press, 2003, pp. 190–91, doi:10.1016/S1534-5807(03)00235-1.
short: J. Montero, C.-P.J. Heisenberg, Developmental Cell 5 (2003) 190–191.
date_created: 2018-12-11T12:07:21Z
date_published: 2003-08-01T00:00:00Z
date_updated: 2024-02-27T09:54:53Z
day: '01'
doi: 10.1016/S1534-5807(03)00235-1
extern: '1'
external_id:
pmid:
- '12919669 '
intvolume: ' 5'
issue: '2'
language:
- iso: eng
month: '08'
oa_version: None
page: 190 - 191
pmid: 1
publication: Developmental Cell
publication_identifier:
eissn:
- 1878-1551
issn:
- 1534-5807
publication_status: published
publisher: Cell Press
publist_id: '1949'
quality_controlled: '1'
scopus_import: '1'
status: public
title: Adhesive crosstalk in gastrulation
type: journal_article
user_id: ea97e931-d5af-11eb-85d4-e6957dddbf17
volume: 5
year: '2003'
...
---
_id: '3991'
abstract:
- lang: eng
text: We give analytic inclusion-exclusion formulas for the area and perimeter derivatives
of a union of finitely many disks in the plane.
acknowledgement: Partially supported by NSF under grant DMS-98-73945 and CCR-00-86013.
alternative_title:
- LNCS
article_processing_charge: No
author:
- first_name: Ho
full_name: Cheng, Ho
last_name: Cheng
- first_name: Herbert
full_name: Edelsbrunner, Herbert
id: 3FB178DA-F248-11E8-B48F-1D18A9856A87
last_name: Edelsbrunner
orcid: 0000-0002-9823-6833
citation:
ama: 'Cheng H, Edelsbrunner H. Area and perimeter derivatives of a union of disks.
In: Computer Science in Perspective: Essays Dedicated to Thomas Ottmann.
Vol 2598. Springer; 2003:88-97. doi:10.1007/3-540-36477-3_7'
apa: 'Cheng, H., & Edelsbrunner, H. (2003). Area and perimeter derivatives of
a union of disks. In Computer Science in Perspective: Essays Dedicated to Thomas
Ottmann (Vol. 2598, pp. 88–97). Springer. https://doi.org/10.1007/3-540-36477-3_7'
chicago: 'Cheng, Ho, and Herbert Edelsbrunner. “Area and Perimeter Derivatives of
a Union of Disks.” In Computer Science in Perspective: Essays Dedicated to
Thomas Ottmann, 2598:88–97. Springer, 2003. https://doi.org/10.1007/3-540-36477-3_7.'
ieee: 'H. Cheng and H. Edelsbrunner, “Area and perimeter derivatives of a union
of disks,” in Computer Science in Perspective: Essays Dedicated to Thomas Ottmann,
vol. 2598, Springer, 2003, pp. 88–97.'
ista: 'Cheng H, Edelsbrunner H. 2003.Area and perimeter derivatives of a union of
disks. In: Computer Science in Perspective: Essays Dedicated to Thomas Ottmann.
LNCS, vol. 2598, 88–97.'
mla: 'Cheng, Ho, and Herbert Edelsbrunner. “Area and Perimeter Derivatives of a
Union of Disks.” Computer Science in Perspective: Essays Dedicated to Thomas
Ottmann, vol. 2598, Springer, 2003, pp. 88–97, doi:10.1007/3-540-36477-3_7.'
short: 'H. Cheng, H. Edelsbrunner, in:, Computer Science in Perspective: Essays
Dedicated to Thomas Ottmann, Springer, 2003, pp. 88–97.'
date_created: 2018-12-11T12:06:18Z
date_published: 2003-02-17T00:00:00Z
date_updated: 2024-02-27T12:15:02Z
day: '17'
doi: 10.1007/3-540-36477-3_7
extern: '1'
intvolume: ' 2598'
language:
- iso: eng
month: '02'
oa_version: None
page: 88 - 97
publication: 'Computer Science in Perspective: Essays Dedicated to Thomas Ottmann'
publication_identifier:
isbn:
- '9783540005797'
publication_status: published
publisher: Springer
publist_id: '2132'
quality_controlled: '1'
scopus_import: '1'
status: public
title: Area and perimeter derivatives of a union of disks
type: book_chapter
user_id: ea97e931-d5af-11eb-85d4-e6957dddbf17
volume: 2598
year: '2003'
...