---
_id: '6157'
abstract:
- lang: eng
text: In many animal species individuals aggregate to live in groups. A range of
experimental approaches in different animals, including studies of social feeding
in nematodes, maternal behavior in rats and sheep, and pair-bonding in voles,
are providing insights into the neural bases for these behaviors. These studies
are delineating multiple neural circuits and gene networks in the brain that interact
in ways that are as yet poorly understood to coordinate social behavior.
author:
- first_name: Mario
full_name: de Bono, Mario
id: 4E3FF80E-F248-11E8-B48F-1D18A9856A87
last_name: de Bono
orcid: 0000-0001-8347-0443
citation:
ama: de Bono M. Molecular approaches to aggregation behavior and social attachment.
Journal of Neurobiology. 2003;54(1):78-92. doi:10.1002/neu.10162
apa: de Bono, M. (2003). Molecular approaches to aggregation behavior and social
attachment. Journal of Neurobiology. Wiley. https://doi.org/10.1002/neu.10162
chicago: Bono, Mario de. “Molecular Approaches to Aggregation Behavior and Social
Attachment.” Journal of Neurobiology. Wiley, 2003. https://doi.org/10.1002/neu.10162.
ieee: M. de Bono, “Molecular approaches to aggregation behavior and social attachment,”
Journal of Neurobiology, vol. 54, no. 1. Wiley, pp. 78–92, 2003.
ista: de Bono M. 2003. Molecular approaches to aggregation behavior and social attachment.
Journal of Neurobiology. 54(1), 78–92.
mla: de Bono, Mario. “Molecular Approaches to Aggregation Behavior and Social Attachment.”
Journal of Neurobiology, vol. 54, no. 1, Wiley, 2003, pp. 78–92, doi:10.1002/neu.10162.
short: M. de Bono, Journal of Neurobiology 54 (2003) 78–92.
date_created: 2019-03-21T09:52:31Z
date_published: 2003-01-01T00:00:00Z
date_updated: 2021-01-12T08:06:26Z
day: '01'
doi: 10.1002/neu.10162
extern: '1'
external_id:
pmid:
- '12486699'
intvolume: ' 54'
issue: '1'
language:
- iso: eng
month: '01'
oa_version: None
page: 78-92
pmid: 1
publication: Journal of Neurobiology
publication_identifier:
issn:
- 0022-3034
- 1097-4695
publication_status: published
publisher: Wiley
quality_controlled: '1'
status: public
title: Molecular approaches to aggregation behavior and social attachment
type: journal_article
user_id: 3E5EF7F0-F248-11E8-B48F-1D18A9856A87
volume: 54
year: '2003'
...
---
_id: '847'
abstract:
- lang: eng
text: The accumulation of genome-wide information on single nucleotide polymorphisms
in humans provides an unprecedented opportunity to detect the evolutionary forces
responsible for heterogeneity of the level of genetic variability across loci.
Previous studies have shown that history of recombination events has produced
long haplotype blocks in the human genome, which contribute to this heterogeneity.
Other factors, however, such as natural selection or the heterogeneity of mutation
rates across loci, may also lead to heterogeneity of genetic variability. We compared
synonymous and non-synonymous variability within human genes with their divergence
from murine orthologs. We separately analyzed the non-synonymous variants predicted
to damage protein structure or function and the variants predicted to be functionally
benign. The predictions were based on comparative sequence analysis and, in some
cases, on the analysis of protein structure. A strong correlation between non-synonymous,
benign variability and non-synonymous human-mouse divergence suggests that selection
played an important role in shaping the pattern of variability in coding regions
of human genes. However, the lack of correlation between deleterious variability
and evolutionary divergence shows that a substantial proportion of the observed
non-synonymous single-nucleotide polymorphisms reduces fitness and never reaches
fixation. Evolutionary and medical implications of the impact of selection on
human polymorphisms are discussed.
acknowledgement: We are grateful to Alexey Kondrashov and Alison Wellman for the careful
reading of the manuscript and providing us with their valuable comments.
author:
- first_name: Shamil
full_name: Sunyaev, Shamil R
last_name: Sunyaev
- first_name: Fyodor
full_name: Fyodor Kondrashov
id: 44FDEF62-F248-11E8-B48F-1D18A9856A87
last_name: Kondrashov
orcid: 0000-0001-8243-4694
- first_name: Peer
full_name: Bork, Peer
last_name: Bork
- first_name: Vasily
full_name: Ramensky, Vasily
last_name: Ramensky
citation:
ama: Sunyaev S, Kondrashov F, Bork P, Ramensky V. Impact of selection, mutation
rate and genetic drift on human genetic variation. Human Molecular Genetics.
2003;12(24):3325-3330. doi:10.1093/hmg/ddg359
apa: Sunyaev, S., Kondrashov, F., Bork, P., & Ramensky, V. (2003). Impact of
selection, mutation rate and genetic drift on human genetic variation. Human
Molecular Genetics. Oxford University Press. https://doi.org/10.1093/hmg/ddg359
chicago: Sunyaev, Shamil, Fyodor Kondrashov, Peer Bork, and Vasily Ramensky. “Impact
of Selection, Mutation Rate and Genetic Drift on Human Genetic Variation.” Human
Molecular Genetics. Oxford University Press, 2003. https://doi.org/10.1093/hmg/ddg359.
ieee: S. Sunyaev, F. Kondrashov, P. Bork, and V. Ramensky, “Impact of selection,
mutation rate and genetic drift on human genetic variation,” Human Molecular
Genetics, vol. 12, no. 24. Oxford University Press, pp. 3325–3330, 2003.
ista: Sunyaev S, Kondrashov F, Bork P, Ramensky V. 2003. Impact of selection, mutation
rate and genetic drift on human genetic variation. Human Molecular Genetics. 12(24),
3325–3330.
mla: Sunyaev, Shamil, et al. “Impact of Selection, Mutation Rate and Genetic Drift
on Human Genetic Variation.” Human Molecular Genetics, vol. 12, no. 24,
Oxford University Press, 2003, pp. 3325–30, doi:10.1093/hmg/ddg359.
short: S. Sunyaev, F. Kondrashov, P. Bork, V. Ramensky, Human Molecular Genetics
12 (2003) 3325–3330.
date_created: 2018-12-11T11:48:49Z
date_published: 2003-12-15T00:00:00Z
date_updated: 2021-01-12T08:19:29Z
day: '15'
doi: 10.1093/hmg/ddg359
extern: 1
intvolume: ' 12'
issue: '24'
month: '12'
page: 3325 - 3330
publication: Human Molecular Genetics
publication_status: published
publisher: Oxford University Press
publist_id: '6803'
quality_controlled: 0
status: public
title: Impact of selection, mutation rate and genetic drift on human genetic variation
type: journal_article
volume: 12
year: '2003'
...
---
_id: '876'
abstract:
- lang: eng
text: Alternative splicing is thought to be a major source of functional diversity
in animal proteins. We analyzed the evolutionary conservation of proteins encoded
by alternatively spliced genes and predicted the ancestral state for 73 cases
of alternative splicing (25 insertions and 48 deletions). The amino acid sequences
of most of the inserts in proteins produced by alternative splicing are as conserved
as the surrounding sequences. Thus, alternative splicing often creates novel isoforms
by the insertion of new, functional protein sequences that probably originated
from noncoding sequences of introns.
acknowledgement: We thank Peer Bork, Mikhail Gelfand, Alexey Kondrashov, David Lipman
and Shamil Sunyaev for critical reading of the manuscript and useful suggestions
and the Koonin group members for helpful discussions.
author:
- first_name: Fyodor
full_name: Fyodor Kondrashov
id: 44FDEF62-F248-11E8-B48F-1D18A9856A87
last_name: Kondrashov
orcid: 0000-0001-8243-4694
- first_name: Eugene
full_name: Koonin, Eugene V
last_name: Koonin
citation:
ama: 'Kondrashov F, Koonin E. Evolution of alternative splicing: Deletions, insertions
and origin of functional parts of proteins from intron sequences. Trends in
Genetics. 2003;19(3):115-119. doi:10.1016/S0168-9525(02)00029-X'
apa: 'Kondrashov, F., & Koonin, E. (2003). Evolution of alternative splicing:
Deletions, insertions and origin of functional parts of proteins from intron sequences.
Trends in Genetics. Elsevier. https://doi.org/10.1016/S0168-9525(02)00029-X'
chicago: 'Kondrashov, Fyodor, and Eugene Koonin. “Evolution of Alternative Splicing:
Deletions, Insertions and Origin of Functional Parts of Proteins from Intron Sequences.”
Trends in Genetics. Elsevier, 2003. https://doi.org/10.1016/S0168-9525(02)00029-X.'
ieee: 'F. Kondrashov and E. Koonin, “Evolution of alternative splicing: Deletions,
insertions and origin of functional parts of proteins from intron sequences,”
Trends in Genetics, vol. 19, no. 3. Elsevier, pp. 115–119, 2003.'
ista: 'Kondrashov F, Koonin E. 2003. Evolution of alternative splicing: Deletions,
insertions and origin of functional parts of proteins from intron sequences. Trends
in Genetics. 19(3), 115–119.'
mla: 'Kondrashov, Fyodor, and Eugene Koonin. “Evolution of Alternative Splicing:
Deletions, Insertions and Origin of Functional Parts of Proteins from Intron Sequences.”
Trends in Genetics, vol. 19, no. 3, Elsevier, 2003, pp. 115–19, doi:10.1016/S0168-9525(02)00029-X.'
short: F. Kondrashov, E. Koonin, Trends in Genetics 19 (2003) 115–119.
date_created: 2018-12-11T11:48:58Z
date_published: 2003-01-01T00:00:00Z
date_updated: 2021-01-12T08:20:58Z
day: '01'
doi: 10.1016/S0168-9525(02)00029-X
extern: 1
intvolume: ' 19'
issue: '3'
month: '01'
page: 115 - 119
publication: Trends in Genetics
publication_status: published
publisher: Elsevier
publist_id: '6776'
quality_controlled: 0
status: public
title: 'Evolution of alternative splicing: Deletions, insertions and origin of functional
parts of proteins from intron sequences'
type: journal_article
volume: 19
year: '2003'
...
---
_id: '9495'
abstract:
- lang: eng
text: RNA interference is a conserved process in which double-stranded RNA is processed
into 21–25 nucleotide siRNAs that trigger posttranscriptional gene silencing.
In addition, plants display a phenomenon termed RNA-directed DNA methylation (RdDM)
in which DNA with sequence identity to silenced RNA is de novo methylated at its
cytosine residues. This methylation is not only at canonical CpG sites but also
at cytosines in CpNpG and asymmetric sequence contexts. In this report, we study
the role of the DRM and CMT3 DNA methyltransferase genes in the initiation and
maintenance of RdDM. Neither drm nor cmt3 mutants affected the maintenance of
preestablished RNA-directed CpG methylation. However, drm mutants showed a nearly
complete loss of asymmetric methylation and a partial loss of CpNpG methylation.
The remaining asymmetric and CpNpG methylation was dependent on the activity of
CMT3, showing that DRM and CMT3 act redundantly to maintain non-CpG methylation.
These DNA methyltransferases appear to act downstream of siRNAs, since drm1 drm2
cmt3 triple mutants show a lack of non-CpG methylation but elevated levels of
siRNAs. Finally, we demonstrate that DRM activity is required for the initial
establishment of RdDM in all sequence contexts including CpG, CpNpG, and asymmetric
sites.
article_processing_charge: No
article_type: original
author:
- first_name: Xiaofeng
full_name: Cao, Xiaofeng
last_name: Cao
- first_name: Werner
full_name: Aufsatz, Werner
last_name: Aufsatz
- first_name: Daniel
full_name: Zilberman, Daniel
id: 6973db13-dd5f-11ea-814e-b3e5455e9ed1
last_name: Zilberman
orcid: 0000-0002-0123-8649
- first_name: M.Florian
full_name: Mette, M.Florian
last_name: Mette
- first_name: Michael S.
full_name: Huang, Michael S.
last_name: Huang
- first_name: Marjori
full_name: Matzke, Marjori
last_name: Matzke
- first_name: Steven E.
full_name: Jacobsen, Steven E.
last_name: Jacobsen
citation:
ama: Cao X, Aufsatz W, Zilberman D, et al. Role of the DRM and CMT3 methyltransferases
in RNA-directed DNA methylation. Current Biology. 2003;13(24):2212-2217.
doi:10.1016/j.cub.2003.11.052
apa: Cao, X., Aufsatz, W., Zilberman, D., Mette, M. F., Huang, M. S., Matzke, M.,
& Jacobsen, S. E. (2003). Role of the DRM and CMT3 methyltransferases in RNA-directed
DNA methylation. Current Biology. Elsevier. https://doi.org/10.1016/j.cub.2003.11.052
chicago: Cao, Xiaofeng, Werner Aufsatz, Daniel Zilberman, M.Florian Mette, Michael
S. Huang, Marjori Matzke, and Steven E. Jacobsen. “Role of the DRM and CMT3 Methyltransferases
in RNA-Directed DNA Methylation.” Current Biology. Elsevier, 2003. https://doi.org/10.1016/j.cub.2003.11.052.
ieee: X. Cao et al., “Role of the DRM and CMT3 methyltransferases in RNA-directed
DNA methylation,” Current Biology, vol. 13, no. 24. Elsevier, pp. 2212–2217,
2003.
ista: Cao X, Aufsatz W, Zilberman D, Mette MF, Huang MS, Matzke M, Jacobsen SE.
2003. Role of the DRM and CMT3 methyltransferases in RNA-directed DNA methylation.
Current Biology. 13(24), 2212–2217.
mla: Cao, Xiaofeng, et al. “Role of the DRM and CMT3 Methyltransferases in RNA-Directed
DNA Methylation.” Current Biology, vol. 13, no. 24, Elsevier, 2003, pp.
2212–17, doi:10.1016/j.cub.2003.11.052.
short: X. Cao, W. Aufsatz, D. Zilberman, M.F. Mette, M.S. Huang, M. Matzke, S.E.
Jacobsen, Current Biology 13 (2003) 2212–2217.
date_created: 2021-06-07T10:43:02Z
date_published: 2003-12-16T00:00:00Z
date_updated: 2021-12-14T08:41:38Z
day: '16'
department:
- _id: DaZi
doi: 10.1016/j.cub.2003.11.052
extern: '1'
external_id:
pmid:
- '14680640'
intvolume: ' 13'
issue: '24'
language:
- iso: eng
main_file_link:
- open_access: '1'
url: https://doi.org/10.1016/j.cub.2003.11.052
month: '12'
oa: 1
oa_version: Published Version
page: 2212-2217
pmid: 1
publication: Current Biology
publication_identifier:
eissn:
- 1879-0445
issn:
- 0960-9822
publication_status: published
publisher: Elsevier
quality_controlled: '1'
scopus_import: '1'
status: public
title: Role of the DRM and CMT3 methyltransferases in RNA-directed DNA methylation
type: journal_article
user_id: 8b945eb4-e2f2-11eb-945a-df72226e66a9
volume: 13
year: '2003'
...
---
_id: '8519'
article_processing_charge: No
article_type: original
author:
- first_name: Vadim
full_name: Kaloshin, Vadim
id: FE553552-CDE8-11E9-B324-C0EBE5697425
last_name: Kaloshin
orcid: 0000-0002-6051-2628
citation:
ama: Kaloshin V. The existential Hilbert 16-th problem and an estimate for cyclicity
of elementary polycycles. Inventiones mathematicae. 2003;151(3):451-512.
doi:10.1007/s00222-002-0244-9
apa: Kaloshin, V. (2003). The existential Hilbert 16-th problem and an estimate
for cyclicity of elementary polycycles. Inventiones Mathematicae. Springer
Nature. https://doi.org/10.1007/s00222-002-0244-9
chicago: Kaloshin, Vadim. “The Existential Hilbert 16-Th Problem and an Estimate
for Cyclicity of Elementary Polycycles.” Inventiones Mathematicae. Springer
Nature, 2003. https://doi.org/10.1007/s00222-002-0244-9.
ieee: V. Kaloshin, “The existential Hilbert 16-th problem and an estimate for cyclicity
of elementary polycycles,” Inventiones mathematicae, vol. 151, no. 3. Springer
Nature, pp. 451–512, 2003.
ista: Kaloshin V. 2003. The existential Hilbert 16-th problem and an estimate for
cyclicity of elementary polycycles. Inventiones mathematicae. 151(3), 451–512.
mla: Kaloshin, Vadim. “The Existential Hilbert 16-Th Problem and an Estimate for
Cyclicity of Elementary Polycycles.” Inventiones Mathematicae, vol. 151,
no. 3, Springer Nature, 2003, pp. 451–512, doi:10.1007/s00222-002-0244-9.
short: V. Kaloshin, Inventiones Mathematicae 151 (2003) 451–512.
date_created: 2020-09-18T10:49:26Z
date_published: 2003-03-01T00:00:00Z
date_updated: 2021-01-12T08:19:50Z
day: '01'
doi: 10.1007/s00222-002-0244-9
extern: '1'
intvolume: ' 151'
issue: '3'
keyword:
- General Mathematics
language:
- iso: eng
month: '03'
oa_version: None
page: 451-512
publication: Inventiones mathematicae
publication_identifier:
issn:
- 0020-9910
- 1432-1297
publication_status: published
publisher: Springer Nature
quality_controlled: '1'
status: public
title: The existential Hilbert 16-th problem and an estimate for cyclicity of elementary
polycycles
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 151
year: '2003'
...
---
_id: '9455'
abstract:
- lang: eng
text: Proteins of the ARGONAUTE family are important in diverse posttranscriptional
RNA-mediated gene-silencing systems as well as in transcriptional gene silencing
in Drosophila and fission yeast and in programmed DNA elimination in Tetrahymena.
We cloned ARGONAUTE4 (AGO4) from a screen for mutants that suppress silencing
of the Arabidopsis SUPERMAN(SUP) gene. The ago4-1 mutant reactivated silentSUP
alleles and decreased CpNpG and asymmetric DNA methylation as well as histone
H3 lysine-9 methylation. In addition,ago4-1 blocked histone and DNA methylation
and the accumulation of 25-nucleotide small interfering RNAs (siRNAs) that correspond
to the retroelement AtSN1. These results suggest that AGO4 and long siRNAs direct
chromatin modifications, including histone methylation and non-CpG DNA methylation.
article_processing_charge: No
article_type: original
author:
- first_name: Daniel
full_name: Zilberman, Daniel
id: 6973db13-dd5f-11ea-814e-b3e5455e9ed1
last_name: Zilberman
orcid: 0000-0002-0123-8649
- first_name: ' Xiaofeng'
full_name: Cao, Xiaofeng
last_name: Cao
- first_name: Steven E.
full_name: Jacobsen, Steven E.
last_name: Jacobsen
citation:
ama: Zilberman D, Cao Xiaofeng, Jacobsen SE. ARGONAUTE4 control of locus-specific
siRNA accumulation and DNA and histone methylation. Science. 2003;299(5607):716-719.
doi:10.1126/science.1079695
apa: Zilberman, D., Cao, Xiaofeng, & Jacobsen, S. E. (2003). ARGONAUTE4 control
of locus-specific siRNA accumulation and DNA and histone methylation. Science.
American Association for the Advancement of Science. https://doi.org/10.1126/science.1079695
chicago: Zilberman, Daniel, Xiaofeng Cao, and Steven E. Jacobsen. “ARGONAUTE4 Control
of Locus-Specific SiRNA Accumulation and DNA and Histone Methylation.” Science.
American Association for the Advancement of Science, 2003. https://doi.org/10.1126/science.1079695.
ieee: D. Zilberman, Xiaofeng Cao, and S. E. Jacobsen, “ARGONAUTE4 control of locus-specific
siRNA accumulation and DNA and histone methylation,” Science, vol. 299,
no. 5607. American Association for the Advancement of Science, pp. 716–719, 2003.
ista: Zilberman D, Cao Xiaofeng, Jacobsen SE. 2003. ARGONAUTE4 control of locus-specific
siRNA accumulation and DNA and histone methylation. Science. 299(5607), 716–719.
mla: Zilberman, Daniel, et al. “ARGONAUTE4 Control of Locus-Specific SiRNA Accumulation
and DNA and Histone Methylation.” Science, vol. 299, no. 5607, American
Association for the Advancement of Science, 2003, pp. 716–19, doi:10.1126/science.1079695.
short: D. Zilberman, Xiaofeng Cao, S.E. Jacobsen, Science 299 (2003) 716–719.
date_created: 2021-06-04T11:26:26Z
date_published: 2003-01-31T00:00:00Z
date_updated: 2021-12-14T08:43:30Z
day: '31'
department:
- _id: DaZi
doi: 10.1126/science.1079695
extern: '1'
external_id:
pmid:
- '12522258'
intvolume: ' 299'
issue: '5607'
keyword:
- Multidisciplinary
language:
- iso: eng
month: '01'
oa_version: None
page: 716-719
pmid: 1
publication: Science
publication_identifier:
eissn:
- 1095-9203
issn:
- 0036-8075
publication_status: published
publisher: American Association for the Advancement of Science
quality_controlled: '1'
scopus_import: '1'
status: public
title: ARGONAUTE4 control of locus-specific siRNA accumulation and DNA and histone
methylation
type: journal_article
user_id: 8b945eb4-e2f2-11eb-945a-df72226e66a9
volume: 299
year: '2003'
...
---
_id: '4628'
abstract:
- lang: eng
text: 'Discounting the future means that the value, today, of a unit payoffis 1
if the payoffo ccurs today, a if it occurs tomorrow, a 2 if it occurs the day
after tomorrow, and so on, for some real-valued discount factor 0 < a <
1. Discounting (or inflation) is a key paradigm in economics and has been studied
in Markov decision processes as well as game theory. We submit that discounting
also has a natural place in systems engineering: for nonterminating systems, a
potential bug in the far-away future is less troubling than a potential bug today.
We therefore develop a systems theory with discounting. Our theory includes several
basic elements: discounted versions of system properties that correspond to the
ω-regular properties, fixpoint-based algorithms for checking discounted properties,
and a quantitative notion of bisimilarity for capturing the difference between
two states with respect to discounted properties. We present the theory in a general
form that applies to probabilistic systems as well as multicomponent systems (games),
but it readily specializes to classical transition systems. We show that discounting,
besides its natural practical appeal, has also several mathematical benefits.
First, the resulting theory is robust, in that small perturbations of a system
can cause only small changes in the properties of the system. Second, the theory
is computational, in that the values of discounted properties, as well as the
discounted bisimilarity distance between states, can be computed to any desired
degree of precision.'
acknowledgement: This research was supported in part by the NSF CAREER award CCR-0132780,
the DARPA grant F33615-C-98-3614, the NSF grants CCR-9988172, CCR-0234690 and CCR-0225610,
and the ONR grant N00014-02-1-0671.
alternative_title:
- LNCS
article_processing_charge: No
author:
- first_name: Luca
full_name: De Alfaro, Luca
last_name: De Alfaro
- first_name: Thomas A
full_name: Henzinger, Thomas A
id: 40876CD8-F248-11E8-B48F-1D18A9856A87
last_name: Henzinger
orcid: 0000−0002−2985−7724
- first_name: Ritankar
full_name: Majumdar, Ritankar
last_name: Majumdar
citation:
ama: 'De Alfaro L, Henzinger TA, Majumdar R. Discounting the future in systems theory.
In: Proceedings of the 30th International Colloquium on Automata, Languages
and Programming. Vol 2719. Springer; 2003:1022-1037. doi:10.1007/3-540-45061-0_79'
apa: 'De Alfaro, L., Henzinger, T. A., & Majumdar, R. (2003). Discounting the
future in systems theory. In Proceedings of the 30th International Colloquium
on Automata, Languages and Programming (Vol. 2719, pp. 1022–1037). Eindhoven,
The Netherlands: Springer. https://doi.org/10.1007/3-540-45061-0_79'
chicago: De Alfaro, Luca, Thomas A Henzinger, and Ritankar Majumdar. “Discounting
the Future in Systems Theory.” In Proceedings of the 30th International Colloquium
on Automata, Languages and Programming, 2719:1022–37. Springer, 2003. https://doi.org/10.1007/3-540-45061-0_79.
ieee: L. De Alfaro, T. A. Henzinger, and R. Majumdar, “Discounting the future in
systems theory,” in Proceedings of the 30th International Colloquium on Automata,
Languages and Programming, Eindhoven, The Netherlands, 2003, vol. 2719, pp.
1022–1037.
ista: 'De Alfaro L, Henzinger TA, Majumdar R. 2003. Discounting the future in systems
theory. Proceedings of the 30th International Colloquium on Automata, Languages
and Programming. ICALP: Automata, Languages and Programming, LNCS, vol. 2719,
1022–1037.'
mla: De Alfaro, Luca, et al. “Discounting the Future in Systems Theory.” Proceedings
of the 30th International Colloquium on Automata, Languages and Programming,
vol. 2719, Springer, 2003, pp. 1022–37, doi:10.1007/3-540-45061-0_79.
short: L. De Alfaro, T.A. Henzinger, R. Majumdar, in:, Proceedings of the 30th International
Colloquium on Automata, Languages and Programming, Springer, 2003, pp. 1022–1037.
conference:
end_date: 2003-07-04
location: Eindhoven, The Netherlands
name: 'ICALP: Automata, Languages and Programming'
start_date: 2003-06-30
date_created: 2018-12-11T12:09:50Z
date_published: 2003-06-25T00:00:00Z
date_updated: 2023-07-26T13:07:31Z
day: '25'
doi: 10.1007/3-540-45061-0_79
extern: '1'
intvolume: ' 2719'
language:
- iso: eng
month: '06'
oa_version: None
page: 1022 - 1037
publication: Proceedings of the 30th International Colloquium on Automata, Languages
and Programming
publication_identifier:
isbn:
- '9783540404934'
publication_status: published
publisher: Springer
publist_id: '77'
quality_controlled: '1'
scopus_import: '1'
status: public
title: Discounting the future in systems theory
type: conference
user_id: ea97e931-d5af-11eb-85d4-e6957dddbf17
volume: 2719
year: '2003'
...
---
_id: '13436'
abstract:
- lang: eng
text: Cross-metathesis reactions of α,β-unsaturated sulfones and sulfoxides in the
presence of molybdenum and ruthenium pre-catalysts were tested. A selective metahesis
reaction was achieved between functionalized terminal olefins and vinyl sulfones
by using the ‘second generation’ ruthenium catalysts 1c–h while the highly active
Schrock catalyst 1b was found to be functional group incompatible with vinyl sulfones.
The cross-metathesis products were isolated in good yields with an excellent (E)-selectivity.
Both the molybdenum and ruthenium-based complexes were, however, incompatible
with α,β- and β,γ-unsaturated sulfoxides.
article_processing_charge: No
article_type: original
author:
- first_name: Anna
full_name: Michrowska, Anna
last_name: Michrowska
- first_name: Michał
full_name: Bieniek, Michał
last_name: Bieniek
- first_name: Mikhail
full_name: Kim, Mikhail
last_name: Kim
- first_name: Rafal
full_name: Klajn, Rafal
id: 8e84690e-1e48-11ed-a02b-a1e6fb8bb53b
last_name: Klajn
- first_name: Karol
full_name: Grela, Karol
last_name: Grela
citation:
ama: Michrowska A, Bieniek M, Kim M, Klajn R, Grela K. Cross-metathesis reaction
of vinyl sulfones and sulfoxides. Tetrahedron. 2003;59(25):4525-4531. doi:10.1016/s0040-4020(03)00682-3
apa: Michrowska, A., Bieniek, M., Kim, M., Klajn, R., & Grela, K. (2003). Cross-metathesis
reaction of vinyl sulfones and sulfoxides. Tetrahedron. Elsevier. https://doi.org/10.1016/s0040-4020(03)00682-3
chicago: Michrowska, Anna, Michał Bieniek, Mikhail Kim, Rafal Klajn, and Karol Grela.
“Cross-Metathesis Reaction of Vinyl Sulfones and Sulfoxides.” Tetrahedron.
Elsevier, 2003. https://doi.org/10.1016/s0040-4020(03)00682-3.
ieee: A. Michrowska, M. Bieniek, M. Kim, R. Klajn, and K. Grela, “Cross-metathesis
reaction of vinyl sulfones and sulfoxides,” Tetrahedron, vol. 59, no. 25.
Elsevier, pp. 4525–4531, 2003.
ista: Michrowska A, Bieniek M, Kim M, Klajn R, Grela K. 2003. Cross-metathesis reaction
of vinyl sulfones and sulfoxides. Tetrahedron. 59(25), 4525–4531.
mla: Michrowska, Anna, et al. “Cross-Metathesis Reaction of Vinyl Sulfones and Sulfoxides.”
Tetrahedron, vol. 59, no. 25, Elsevier, 2003, pp. 4525–31, doi:10.1016/s0040-4020(03)00682-3.
short: A. Michrowska, M. Bieniek, M. Kim, R. Klajn, K. Grela, Tetrahedron 59 (2003)
4525–4531.
date_created: 2023-08-01T10:39:34Z
date_published: 2003-06-16T00:00:00Z
date_updated: 2023-08-08T12:44:17Z
day: '16'
doi: 10.1016/s0040-4020(03)00682-3
extern: '1'
intvolume: ' 59'
issue: '25'
keyword:
- Organic Chemistry
- Drug Discovery
- Biochemistry
language:
- iso: eng
month: '06'
oa_version: None
page: 4525-4531
publication: Tetrahedron
publication_identifier:
eissn:
- 1464-5416
issn:
- 0040-4020
publication_status: published
publisher: Elsevier
quality_controlled: '1'
scopus_import: '1'
status: public
title: Cross-metathesis reaction of vinyl sulfones and sulfoxides
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 59
year: '2003'
...
---
_id: '4561'
abstract:
- lang: eng
text: 'We present a formalism for specifying component interfaces that expose component
requirements on limited resources. The formalism permits an algorithmic check
if two or more components, when put together, exceed the available resources.
Moreover, the formalism can be used to compute the quantity of resources necessary
for satisfying the requirements of a collection of components. The formalism can
be instantiated in several ways. For example, several components may draw power
from the same source. Then, the formalism supports compatibility checks such as:
can two components, when put together, achieve their tasks without ever exceeding
the available amount of peak power? or, can they achieve their tasks by using
no more than the initially available amount of energy (i.e., power accumulated
over time)? The corresponding quantitative questions that our algorithms answer
are the following: what is the amount of peak power needed for two components
to be put together? what is the corresponding amount of initial energy? To solve
these questions, we model interfaces with resource requirements as games with
quantitative objectives. The games are played on state spaces where each state
is labeled by a number (representing, e.g., power consumption), and a play produces
an infinite path of labels. The objective may be, for example, to minimize the
largest label that occurs during a play. We illustrate our approach by modeling
compatibility questions for the components of robot control software, and of wireless
sensor networks.'
acknowledgement: This research was supported in part by the DARPA grant F33615-00-C-1693,
the MARCO grant 98-DT-660, the ONR grant N00014-02-1-0671, and the NSF grants CCR-0085949,
CCR-0132780, CCR-0234690, and CCR-9988172.
alternative_title:
- LNCS
article_processing_charge: No
author:
- first_name: Arindam
full_name: Chakrabarti, Arindam
last_name: Chakrabarti
- first_name: Luca
full_name: De Alfaro, Luca
last_name: De Alfaro
- first_name: Thomas A
full_name: Henzinger, Thomas A
id: 40876CD8-F248-11E8-B48F-1D18A9856A87
last_name: Henzinger
orcid: 0000−0002−2985−7724
- first_name: Mariëlle
full_name: Stoelinga, Mariëlle
last_name: Stoelinga
citation:
ama: 'Chakrabarti A, De Alfaro L, Henzinger TA, Stoelinga M. Resource interfaces.
In: Third International Conference on Embedded Software. Vol 2855. ACM;
2003:117-133. doi:10.1007/978-3-540-45212-6_9'
apa: 'Chakrabarti, A., De Alfaro, L., Henzinger, T. A., & Stoelinga, M. (2003).
Resource interfaces. In Third International Conference on Embedded Software
(Vol. 2855, pp. 117–133). Philadelphia, PA, USA: ACM. https://doi.org/10.1007/978-3-540-45212-6_9'
chicago: Chakrabarti, Arindam, Luca De Alfaro, Thomas A Henzinger, and Mariëlle
Stoelinga. “Resource Interfaces.” In Third International Conference on Embedded
Software, 2855:117–33. ACM, 2003. https://doi.org/10.1007/978-3-540-45212-6_9.
ieee: A. Chakrabarti, L. De Alfaro, T. A. Henzinger, and M. Stoelinga, “Resource
interfaces,” in Third International Conference on Embedded Software, Philadelphia,
PA, USA, 2003, vol. 2855, pp. 117–133.
ista: 'Chakrabarti A, De Alfaro L, Henzinger TA, Stoelinga M. 2003. Resource interfaces.
Third International Conference on Embedded Software. EMSOFT: Embedded Software
, LNCS, vol. 2855, 117–133.'
mla: Chakrabarti, Arindam, et al. “Resource Interfaces.” Third International
Conference on Embedded Software, vol. 2855, ACM, 2003, pp. 117–33, doi:10.1007/978-3-540-45212-6_9.
short: A. Chakrabarti, L. De Alfaro, T.A. Henzinger, M. Stoelinga, in:, Third International
Conference on Embedded Software, ACM, 2003, pp. 117–133.
conference:
end_date: 2003-10-15
location: Philadelphia, PA, USA
name: 'EMSOFT: Embedded Software '
start_date: 2003-10-13
date_created: 2018-12-11T12:09:29Z
date_published: 2003-09-29T00:00:00Z
date_updated: 2024-01-08T10:48:11Z
day: '29'
doi: 10.1007/978-3-540-45212-6_9
extern: '1'
intvolume: ' 2855'
language:
- iso: eng
month: '09'
oa_version: None
page: 117 - 133
publication: Third International Conference on Embedded Software
publication_identifier:
isbn:
- '9783540202233'
publication_status: published
publisher: ACM
publist_id: '148'
quality_controlled: '1'
scopus_import: '1'
status: public
title: Resource interfaces
type: conference
user_id: ea97e931-d5af-11eb-85d4-e6957dddbf17
volume: 2855
year: '2003'
...
---
_id: '4630'
abstract:
- lang: eng
text: We consider concurrent two-person games played in real time, in which the
players decide both which action to play, and when to play it. Such timed games
differ from untimed games in two essential ways. First, players can take each
other by surprise, because actions are played with delays that cannot be anticipated
by the opponent. Second, a player should not be able to win the game by preventing
time from diverging. We present a model of timed games that preserves the element
of surprise and accounts for time divergence in a way that treats both players
symmetrically and applies to all ω-regular winning conditions. We prove that the
ability to take each other by surprise adds extra power to the players. For the
case that the games are specified in the style of timed automata, we provide symbolic
algorithms for their solution with respect to all ω-regular winning conditions.
We also show that for these timed games, memory strategies are more powerful than
memoryless strategies already in the case of reachability objectives.
acknowledgement: Supported in part by the AFOSR MURI grant F49620-00-1-0327, the DARPA
grant F33615-C-98-3614, the MARCO grant 98-DT-660, -the ONR grant N00014-02-1-0671,
the NSF grants CCR-9988172, CCR-0225610, and CCR-0234690, the NSF CAREER award CCR-0132780,
and the MIUR grant MEFISTO.
alternative_title:
- LNCS
article_processing_charge: No
author:
- first_name: Luca
full_name: De Alfaro, Luca
last_name: De Alfaro
- first_name: Marco
full_name: Faella, Marco
last_name: Faella
- first_name: Thomas A
full_name: Henzinger, Thomas A
id: 40876CD8-F248-11E8-B48F-1D18A9856A87
last_name: Henzinger
orcid: 0000−0002−2985−7724
- first_name: Ritankar
full_name: Majumdar, Ritankar
last_name: Majumdar
- first_name: Mariëlle
full_name: Stoelinga, Mariëlle
last_name: Stoelinga
citation:
ama: 'De Alfaro L, Faella M, Henzinger TA, Majumdar R, Stoelinga M. The element
of surprise in timed games. In: Proceedings of the 14th International Conference
on Concurrency Theory. Vol 2761. Schloss Dagstuhl - Leibniz-Zentrum für Informatik;
2003:144-158. doi:10.1007/978-3-540-45187-7_9'
apa: 'De Alfaro, L., Faella, M., Henzinger, T. A., Majumdar, R., & Stoelinga,
M. (2003). The element of surprise in timed games. In Proceedings of the 14th
International Conference on Concurrency Theory (Vol. 2761, pp. 144–158). Marseille,
France: Schloss Dagstuhl - Leibniz-Zentrum für Informatik. https://doi.org/10.1007/978-3-540-45187-7_9'
chicago: De Alfaro, Luca, Marco Faella, Thomas A Henzinger, Ritankar Majumdar, and
Mariëlle Stoelinga. “The Element of Surprise in Timed Games.” In Proceedings
of the 14th International Conference on Concurrency Theory, 2761:144–58. Schloss
Dagstuhl - Leibniz-Zentrum für Informatik, 2003. https://doi.org/10.1007/978-3-540-45187-7_9.
ieee: L. De Alfaro, M. Faella, T. A. Henzinger, R. Majumdar, and M. Stoelinga, “The
element of surprise in timed games,” in Proceedings of the 14th International
Conference on Concurrency Theory, Marseille, France, 2003, vol. 2761, pp.
144–158.
ista: 'De Alfaro L, Faella M, Henzinger TA, Majumdar R, Stoelinga M. 2003. The element
of surprise in timed games. Proceedings of the 14th International Conference on
Concurrency Theory. CONCUR: Concurrency Theory, LNCS, vol. 2761, 144–158.'
mla: De Alfaro, Luca, et al. “The Element of Surprise in Timed Games.” Proceedings
of the 14th International Conference on Concurrency Theory, vol. 2761, Schloss
Dagstuhl - Leibniz-Zentrum für Informatik, 2003, pp. 144–58, doi:10.1007/978-3-540-45187-7_9.
short: L. De Alfaro, M. Faella, T.A. Henzinger, R. Majumdar, M. Stoelinga, in:,
Proceedings of the 14th International Conference on Concurrency Theory, Schloss
Dagstuhl - Leibniz-Zentrum für Informatik, 2003, pp. 144–158.
conference:
end_date: 2003-09-05
location: Marseille, France
name: 'CONCUR: Concurrency Theory'
start_date: 2003-09-03
date_created: 2018-12-11T12:09:51Z
date_published: 2003-08-21T00:00:00Z
date_updated: 2024-01-08T10:05:30Z
day: '21'
doi: 10.1007/978-3-540-45187-7_9
extern: '1'
intvolume: ' 2761'
language:
- iso: eng
month: '08'
oa_version: None
page: 144 - 158
publication: Proceedings of the 14th International Conference on Concurrency Theory
publication_identifier:
isbn:
- '9783540407539'
publication_status: published
publisher: Schloss Dagstuhl - Leibniz-Zentrum für Informatik
publist_id: '78'
quality_controlled: '1'
scopus_import: '1'
status: public
title: The element of surprise in timed games
type: conference
user_id: ea97e931-d5af-11eb-85d4-e6957dddbf17
volume: 2761
year: '2003'
...